GO:0047696

From wiki-pain
Jump to: navigation, search
Name beta-adrenergic receptor kinase activity
Categary Function
Go Slim No
Go Link GO:0047696
Unique Molecular Interactions 53
Total Molecular Interactions 54
Total Single Events 418
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for beta-adrenergic receptor kinase activity. They are ordered first by their pain relevance and then by number of times they were reported for beta-adrenergic receptor kinase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 0.39 1.04 1.45
2 INT169801 Binding of Adrbk1 and Rapgef3 1 0.34 1.04 1.43
3 INT166301 Adrbk1 Positive_regulation of Localization of Trpv1 1 0.45 1.17 1.2
4 INT169802 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Rapgef3 1 0.44 0.75 1.19
5 INT146496 Snta1 Positive_regulation of Gene_expression of Adrbk1 1 0.13 0.73 1.05
6 INT146495 Snta1 Positive_regulation of Adrbk1 1 0.14 0.68 0.85
7 INT124384 ADRBK1 Negative_regulation of MC1R 1 0.40 0.42 0.77
8 INT104110 Negative_regulation of Adrbk2 Negative_regulation of Oprm1 1 0.00 0 0.71
9 INT104102 Negative_regulation of Adrbk2 Negative_regulation of Oprl1 1 0.06 0 0.7
10 INT140235 ADRBK1 Positive_regulation of Binding of MC1R 1 0.46 0.31 0.68
11 INT140237 Gene_expression of ADRBK1 Positive_regulation of Gene_expression of MC1R 1 0.46 0.31 0.68
12 INT166300 Adrbk1 Positive_regulation of Negative_regulation of Gpbar1 1 0.39 0.63 0.58
13 INT106394 MAPK3 Positive_regulation of ADRBK1 1 0.48 0.06 0.53
14 INT106392 ADRBK1 Regulation of Negative_regulation of OPRL1 1 0.27 0.06 0.52
15 INT151222 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Adrbk1 1 0.00 0.13 0.51
16 INT151223 Negative_regulation of SIGMAR1 Negative_regulation of Adrbk1 1 0.00 0.13 0.51
17 INT81331 ADRBK1 Regulation of OPRK1 1 0.03 0.09 0.48
18 INT106395 DYT10 Positive_regulation of ADRBK2 1 0.44 0 0.42
19 INT156122 Phosphorylation of Src Positive_regulation of Adrbk1 1 0.01 0 0.37
20 INT265145 Calm2 Negative_regulation of Phosphorylation of Adrbk1 1 0.05 0.07 0.35
21 INT102974 Binding of ADRBK2 and Rbm39 1 0.00 0 0.31
22 INT106397 Positive_regulation of OPRL1 Positive_regulation of ADRBK1 1 0.46 0.09 0.31
23 INT102976 Binding of ADRBK1 and Rbm39 1 0.00 0 0.31
24 INT265138 Adrbk1 Positive_regulation of Localization of Chrm1 1 0.07 0 0.31
25 INT116680 Binding of ADRBK1 and Oxtr 1 0.18 0.14 0.3
26 INT102953 OPRK1 Positive_regulation of Localization of ADRBK2 1 0.13 0 0.3
27 INT102955 OPRK1 Positive_regulation of Localization of ADRBK1 1 0.13 0 0.3
28 INT83568 Adrbk2 Regulation of Oprk1 1 0.02 0 0.29
29 INT224087 Adrbk1 Negative_regulation of Adora2a 1 0.10 0.13 0.22
30 INT224094 Adrbk1 Regulation of Negative_regulation of Adora2a 1 0.06 0 0.17
31 INT224092 Adrbk1 Regulation of Grk5 1 0.08 0 0.16
32 INT102975 ADRBK1 Regulation of Localization of Rbm39 1 0.00 0 0.15
33 INT102973 ADRBK2 Regulation of Localization of Rbm39 1 0.00 0 0.15
34 INT102954 Binding of ADRBK1 and OPRK1 1 0.11 0 0.14
35 INT224125 Adrbk2 Positive_regulation of Phosphorylation of Adora3 1 0.04 0 0.13
36 INT72849 RT1-EC2 Positive_regulation of Adrbk1 1 0.01 0.33 0.1
37 INT72848 RT1-EC2 Positive_regulation of Adrbk2 1 0.00 0.33 0.1
38 INT72847 Adrbk2 Positive_regulation of Adrbk1 1 0.02 0.33 0.1
39 INT223039 Gene_expression of TFPI Positive_regulation of Gene_expression of ADRBK1 1 0.11 0 0.07
40 INT223043 Gene_expression of TFPI Positive_regulation of Gene_expression of ADRBK2 1 0.12 0 0.07
41 INT223041 Binding of ADRBK1 and TFPI 1 0.08 0 0.03
42 INT223038 Binding of ADRBK2 and TFPI 1 0.09 0 0.03
43 INT223037 SLURP1 Positive_regulation of Gene_expression of ADRBK1 1 0.02 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for beta-adrenergic receptor kinase activity. They are ordered first by their pain relevance and then by number of times they were reported in beta-adrenergic receptor kinase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT50778 Gene_expression of Adrbk1 24 0.77 11.61 20.73
2 INT54708 Gene_expression of Adrbk1 22 0.75 1.06 20.62
3 INT112930 Negative_regulation of Adrbk1 17 0.58 15.04 20.41
4 INT143098 Negative_regulation of Gene_expression of Adrbk1 9 0.58 8.51 11.37
5 INT54706 Regulation of Adrbk1 11 0.62 0.89 10.69
6 INT54707 Positive_regulation of Adrbk1 14 0.67 0.51 9.51
7 INT81345 Gene_expression of ADRBK1 21 0.70 2.89 7.9
8 INT98856 Negative_regulation of Gene_expression of Adrbk1 5 0.56 0.43 7.29
9 INT50779 Positive_regulation of Gene_expression of Adrbk1 9 0.56 2.79 7.23
10 INT54713 Gene_expression of Adrbk2 12 0.65 0.08 5.92
11 INT100741 Positive_regulation of ADRBK1 10 0.64 1.01 3.95
12 INT80891 Gene_expression of ADRBK2 6 0.65 0.63 3.83
13 INT102968 Positive_regulation of ADRBK2 7 0.56 0.59 3.24
14 INT54709 Positive_regulation of Gene_expression of Adrbk1 6 0.49 0.18 3.12
15 INT105840 Regulation of Gene_expression of Adrbk1 2 0.44 0.16 3.09
16 INT102969 Positive_regulation of Gene_expression of ADRBK1 7 0.46 1.21 2.87
17 INT99592 Regulation of Adrbk1 3 0.61 1.46 2.84
18 INT110503 Negative_regulation of ADRBK1 4 0.53 0.71 2.69
19 INT94978 Negative_regulation of Adrbk1 6 0.38 0.13 2.47
20 INT72842 Phosphorylation of Adrbk1 5 0.47 0.58 2.16
21 INT146491 Binding of Adrbk1 3 0.48 1.58 2.09
22 INT102971 Localization of ADRBK2 4 0.63 0.45 1.85
23 INT102970 Localization of ADRBK1 4 0.66 0.45 1.85
24 INT73870 Positive_regulation of Regulation of Adrbk1 1 0.47 0.17 1.66
25 INT83563 Positive_regulation of Gene_expression of Adrbk2 2 0.58 0 1.57
26 INT54711 Regulation of Adrbk2 1 0.59 0 1.57
27 INT104106 Localization of Adrbk2 3 0.19 0.35 1.53
28 INT94965 Transcription of Adrbk1 2 0.22 0.13 1.52
29 INT80886 Positive_regulation of Gene_expression of ADRBK2 4 0.55 0.28 1.39
30 INT94972 Transcription of ADRBK2 1 0.52 0.13 1.37
31 INT54712 Positive_regulation of Adrbk2 3 0.66 0.34 1.35
32 INT151216 Positive_regulation of Adrbk1 2 0.46 0.9 1.3
33 INT94967 Localization of Adrbk1 2 0.26 0.33 1.21
34 INT80879 Positive_regulation of Phosphorylation of ADRBK2 1 0.37 0.12 1.19
35 INT112931 Negative_regulation of Localization of Adrbk1 1 0.37 0 1.13
36 INT112932 Localization of Adrbk1 1 0.69 0 1.12
37 INT106404 Positive_regulation of Positive_regulation of ADRBK1 2 0.41 0.31 1.08
38 INT98849 Binding of Adrbk1 3 0.36 0.18 1.04
39 INT98855 Negative_regulation of Binding of Adrbk1 2 0.41 0.18 1.04
40 INT83566 Negative_regulation of Adrbk2 2 0.23 0 1.03
41 INT146492 Positive_regulation of Negative_regulation of Adrbk1 1 0.50 0.74 1
42 INT111883 Negative_regulation of Transcription of Adrbk1 1 0.33 0 0.93
43 INT111887 Transcription of Adrbk1 1 0.56 0 0.92
44 INT110509 Regulation of ADRBK2 2 0.24 0.22 0.76
45 INT110508 Positive_regulation of Positive_regulation of ADRBK2 2 0.41 0.22 0.76
46 INT110507 Negative_regulation of ADRBK2 1 0.35 0.22 0.76
47 INT110511 Regulation of ADRBK1 1 0.22 0.22 0.76
48 INT110505 Positive_regulation of Negative_regulation of ADRBK1 1 0.38 0.22 0.76
49 INT104103 Positive_regulation of Localization of Adrbk2 1 0.08 0 0.69
50 INT54710 Regulation of Regulation of Adrbk1 1 0.37 0 0.69
51 INT224102 Negative_regulation of Localization of Adrbk1 1 0.19 0.44 0.61
52 INT80889 Phosphorylation of ADRBK2 1 0.49 0.06 0.59
53 INT137480 Positive_regulation of Positive_regulation of Adrbk1 1 0.44 0.06 0.55
54 INT126960 Phosphorylation of ADRBK1 2 0.66 0.06 0.52
55 INT116677 Binding of ADRBK1 6 0.44 0.65 0.5
56 INT224110 Positive_regulation of Phosphorylation of Adrbk1 2 0.28 0 0.45
57 INT86728 Negative_regulation of Positive_regulation of Adrbk1 1 0.38 0 0.45
58 INT223052 Binding of ADRBK2 5 0.20 0 0.34
59 INT83561 Negative_regulation of Negative_regulation of Adrbk2 1 0.23 0 0.34
60 INT116676 Negative_regulation of Binding of ADRBK1 2 0.53 0.33 0.23
61 INT224104 Regulation of Phosphorylation of Adrbk1 1 0.14 0.07 0.17
62 INT223054 Regulation of Gene_expression of ADRBK2 1 0.24 0 0.16
63 INT224123 Transcription of Adrbk2 1 0.24 0 0.15
64 INT181222 Phosphorylation of Adrbk1 1 0.16 0 0.14
65 INT72844 Phosphorylation of Adrbk2 1 0.16 0.33 0.12
66 INT223056 Regulation of Gene_expression of ADRBK1 1 0.22 0 0.12
67 INT223047 Regulation of Binding of ADRBK2 1 0.24 0 0.04
68 INT223046 Positive_regulation of Localization of ADRBK1 1 0.24 0 0
69 INT223058 Positive_regulation of Localization of ADRBK2 1 0.27 0 0
70 INT181220 Negative_regulation of Binding of Adrbk1 1 0.11 0 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox