GO:0048008

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Name platelet-derived growth factor receptor signaling pathway
Categary Process
Go Slim No
Go Link GO:0048008
Unique Molecular Interactions 951
Total Molecular Interactions 1478
Total Single Events 10263
Pain Genes Associated 37

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for platelet-derived growth factor receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for platelet-derived growth factor receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
2 INT334532 Sema3a Negative_regulation of Gene_expression of Nrp1 1 0.19 7.58 2
3 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
4 INT141907 F2r Regulation of Plat 1 0.46 0 1.59
5 INT105112 Plat Positive_regulation of JUN 1 0.01 1.55 1.58
6 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
7 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
8 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
9 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 0.08 0.65 1.35
10 INT18659 Plat Regulation of ZC3H12D 1 0.02 0.1 1.29
11 INT271602 Binding of Pdgfa and Pdgfrl 1 0.02 0.86 1.25
12 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23
13 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
14 INT204558 Tens1 Negative_regulation of Pdgfc 1 0.01 0.25 1.2
15 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
16 INT146352 Binding of Rgs14 and Mors1 1 0.23 0.27 1.17
17 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12
18 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
19 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
20 INT105113 Plat Positive_regulation of NFKB1 1 0.03 1.06 1.06
21 INT121743 Negative_regulation of Src Negative_regulation of Ephb1 1 0.27 0 1.02
22 INT121744 Src Positive_regulation of Positive_regulation of Ephb1 1 0.35 0 0.96
23 INT161231 Positive_regulation of Htr1a Positive_regulation of Gene_expression of VEGFA 1 0.67 0.16 0.95
24 INT137922 VEGFA Positive_regulation of Oprm1 1 0.06 0 0.94
25 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
26 INT137921 VEGFA Positive_regulation of Ephb2 1 0.03 0 0.93
27 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
28 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
29 INT271601 Pdgfa Positive_regulation of Pdgfrl 1 0.03 0.83 0.91
30 INT249491 Efnb2 Positive_regulation of Phosphorylation of Src 1 0.01 0.5 0.87
31 INT116108 VEGFA Positive_regulation of SEC23IP 1 0.10 0.3 0.83
32 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
33 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83
34 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
35 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
36 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
37 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
38 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 0.06 0.29 0.74
39 INT259556 PLEK Negative_regulation of Gene_expression of VEGFA 1 0.46 2.15 0.73
40 INT259557 PLEK Negative_regulation of Positive_regulation of VEGFA 1 0.46 2.15 0.73
41 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
42 INT120018 VEGFA Positive_regulation of CCL3 1 0.01 1 0.7
43 INT120020 VEGFA Positive_regulation of CCL2 1 0.00 1 0.7
44 INT260832 Binding of NRP2 and Nrp1 1 0.00 2.32 0.7
45 INT120036 VEGFA Positive_regulation of Prap1 1 0.00 1 0.7
46 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
47 INT167355 VEGFA Regulation of RYBP 1 0.01 0.53 0.68
48 INT74728 Binding of Slc6a4 and Ptprj 1 0.01 0.48 0.68
49 INT124257 Plat Positive_regulation of Jun 5 0.12 3.33 0.67
50 INT168295 PROC Regulation of Gene_expression of VEGFA 2 0.00 1.6 0.67
51 INT194857 Positive_regulation of Adora2a Positive_regulation of Gene_expression of Vegfa 1 0.23 0.74 0.67
52 INT74729 Binding of Mpz and Ptprj 1 0.06 0.15 0.66
53 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
54 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 0.44 0.06 0.65
55 INT174860 VEGFA Positive_regulation of Localization of CCL2 1 0.21 1.68 0.63
56 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
57 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61
58 INT224731 Binding of VEGFA and Cia1 1 0.01 0.91 0.61
59 INT224733 Negative_regulation of Binding of VEGFA and Cia1 1 0.01 0.91 0.61
60 INT98629 VEGFA Positive_regulation of Gene_expression of EGR1 1 0.52 0.42 0.61
61 INT98628 VEGFA Positive_regulation of Transcription of EGR1 1 0.52 0.42 0.61
62 INT145661 Ptger2 Positive_regulation of Gene_expression of VEGFA 4 0.27 2.73 0.6
63 INT299286 VEGFA Positive_regulation of PI3 1 0.16 0.46 0.6
64 INT56700 Penk Regulation of FER 1 0.00 0 0.59
65 INT54942 Rb1 Regulation of Gab1 1 0.02 0.39 0.59
66 INT342624 VEGFA Negative_regulation of Mmp2 1 0.09 1.54 0.58
67 INT100225 Binding of Egf and Src 1 0.01 0.67 0.58
68 INT327339 Gtf3a Positive_regulation of VEGFA 1 0.00 2.34 0.58
69 INT304326 Ptger1 Positive_regulation of Gene_expression of VEGFA 1 0.19 1.37 0.57
70 INT342621 VEGFA Negative_regulation of Timp2 1 0.09 1.53 0.57
71 INT145718 Positive_regulation of Plat Positive_regulation of Bdnf 1 0.20 0 0.56
72 INT105111 Negative_regulation of Plat Positive_regulation of NFKB1 1 0.03 0.53 0.54
73 INT194918 Csf2 Positive_regulation of Gene_expression of VEGFA 1 0.02 0.85 0.52
74 INT194919 Kitl Positive_regulation of Gene_expression of VEGFA 1 0.01 0.85 0.52
75 INT160203 Prkcc Positive_regulation of Src 1 0.02 0 0.51
76 INT98737 Src Negative_regulation of Tk1 1 0.22 0.15 0.5
77 INT127430 VEGFA Negative_regulation of Gene_expression of TIMP1 1 0.43 0.6 0.5
78 INT98735 Src Negative_regulation of Egf 1 0.26 0.15 0.5
79 INT327332 VEGFA Positive_regulation of Gene_expression of Hgfac 1 0.00 2.02 0.49
80 INT288376 IL17A Regulation of VEGFA 1 0.00 1.16 0.49
81 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48
82 INT260858 IL6 Positive_regulation of Gene_expression of VEGFA 2 0.31 1.77 0.48
83 INT305547 VEGFA Positive_regulation of Gtf3a 2 0.00 1.83 0.48
84 INT260836 Il18 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.48
85 INT134048 Jak2 Regulation of Pik3cb 1 0.23 0.13 0.47
86 INT331928 Negative_regulation of Cpox Negative_regulation of VEGFA 1 0.01 0.97 0.47
87 INT134045 Jak2 Regulation of Stat3 1 0.26 0.13 0.47
88 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
89 INT173475 Bcar1 Regulation of Isl1 1 0.01 0 0.47
90 INT314053 VEGFA Positive_regulation of Gene_expression of Mmp2 1 0.02 0.2 0.47
91 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
92 INT260843 Il6 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47
93 INT260838 Il17a Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47
94 INT134050 Positive_regulation of Jak2 Regulation of Stat3 1 0.44 0.13 0.47
95 INT147444 PDGFA Positive_regulation of Gene_expression of Ros1 2 0.00 0.95 0.46
96 INT276218 Binding of Akt1 and Pten 1 0.26 0.08 0.46
97 INT224698 Il17a Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46
98 INT224699 Il18 Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46
99 INT224451 Il1 Positive_regulation of Gene_expression of VEGFA 1 0.10 1.08 0.45
100 INT224434 TNF Positive_regulation of VEGFA 1 0.10 2.04 0.44
101 INT311587 CXCL10 Regulation of Gene_expression of VEGFA 1 0.23 0.45 0.43
102 INT353109 Binding of VEGFA and Aes 1 0.02 3.93 0.43
103 INT311589 EGF Regulation of Gene_expression of VEGFA 1 0.18 0.51 0.43
104 INT54945 Gab1 Regulation of Positive_regulation of Ltp 1 0.01 0.29 0.42
105 INT254350 FASLG Negative_regulation of Gene_expression of VEGFA 1 0.06 0.92 0.42
106 INT54946 Gab1 Regulation of Ltp 1 0.01 0.29 0.42
107 INT153720 Binding of VEGFA and Pscs 1 0.32 3.12 0.41
108 INT132730 Plat Positive_regulation of Il6 1 0.08 0.76 0.41
109 INT132729 Plat Positive_regulation of Il1b 1 0.09 0.76 0.41
110 INT295709 PTGER2 Regulation of VEGFA 1 0.01 1.61 0.41
111 INT124260 Plat Positive_regulation of Mapk1 1 0.14 0.81 0.41
112 INT237414 Binding of Jak2 and Bace1 1 0.20 0.77 0.39
113 INT304319 Ptger1 Positive_regulation of Gene_expression of Vegfa 1 0.37 1.19 0.39
114 INT285205 Binding of VEGFA and SLEB1 1 0.05 5.12 0.38
115 INT328828 Binding of Jak2 and Jak1 1 0.24 0 0.38
116 INT328827 Binding of Jak2 and Il6st 1 0.05 0 0.38
117 INT328820 Binding of Il6 and Jak2 1 0.09 0 0.38
118 INT342623 Binding of VEGFA and Col18a1 1 0.02 1.15 0.37
119 INT342606 Binding of MMP14 and VEGFA 1 0.08 1.16 0.37
120 INT277353 VEGFA Regulation of Mtor 1 0.02 1.11 0.37
121 INT156122 Phosphorylation of Src Positive_regulation of Adrbk1 1 0.01 0 0.37
122 INT277355 VEGFA Regulation of Trerf1 1 0.08 1.17 0.37
123 INT263380 Binding of Src and Abl1 1 0.21 0 0.37
124 INT277354 Gene_expression of VEGFA Regulation of Mtor 1 0.02 1.1 0.37
125 INT277352 Gene_expression of VEGFA Regulation of Trerf1 1 0.08 1.16 0.37
126 INT329449 IL17A Regulation of Gene_expression of Vegfa 1 0.28 0.63 0.36
127 INT263434 Src Regulation of Abl1 1 0.02 0.29 0.35
128 INT203395 Edn1 Positive_regulation of Vegfa 1 0.06 1.59 0.35
129 INT263382 Src Regulation of Trib3 1 0.00 0.29 0.35
130 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34
131 INT352231 VEGFA Negative_regulation of Cntf 1 0.04 0.22 0.34
132 INT352230 VEGFA Negative_regulation of Gene_expression of Cntf 1 0.04 0.22 0.34
133 INT173476 Th Regulation of Gene_expression of Bcar1 1 0.10 0 0.34
134 INT352232 VEGFA Negative_regulation of Vegfa 1 0.02 0.21 0.34
135 INT23882 Npy Positive_regulation of Bcar1 1 0.34 0.67 0.34
136 INT249490 Phosphorylation of Ephb2 Positive_regulation of Src 1 0.17 0.15 0.33
137 INT110691 Lta Positive_regulation of Gene_expression of VEGFA 1 0.24 0.48 0.33
138 INT295717 VEGFA Regulation of MMP9 1 0.01 0.98 0.33
139 INT184084 Jak2 Positive_regulation of Stat1 1 0.33 0.3 0.33
140 INT93896 Plat Positive_regulation of Gtf3a 1 0.00 0.51 0.32
141 INT329448 IL17A Positive_regulation of Gene_expression of Vegfa 1 0.45 0.59 0.32
142 INT243622 Twist1 Regulation of Jak2 1 0.30 0.2 0.32
143 INT124259 Negative_regulation of Plat Positive_regulation of Jun 4 0.11 1.74 0.31
144 INT142286 Binding of PLG and Plat 2 0.52 0.7 0.31
145 INT316884 Positive_regulation of Binding of Cr2 and Bcr 1 0.06 0.86 0.31
146 INT249480 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Src 1 0.22 0.23 0.31
147 INT54943 Gab1 Regulation of Rb1 1 0.02 0.2 0.31
148 INT316881 Positive_regulation of Binding of Cd19 and Bcr 1 0.08 0.86 0.31
149 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 0.39 5.18 0.3
150 INT316885 Binding of Cr2 and Bcr 1 0.06 0.85 0.3
151 INT316888 Binding of Cd19 and Bcr 1 0.08 0.85 0.3
152 INT225021 PDGFB Positive_regulation of Ccl21 1 0.10 0.07 0.3
153 INT210953 Binding of VEGFA and Csf2 1 0.00 0.47 0.3
154 INT281797 Positive_regulation of Chrna4 Positive_regulation of Gene_expression of VEGFA 1 0.01 0.43 0.3
155 INT333398 CFD Negative_regulation of Gene_expression of Pdgfa 1 0.02 0.64 0.3
156 INT225026 PDGFB Positive_regulation of Gene_expression of Ccl21 1 0.10 0.07 0.3
157 INT235957 Binding of Mog and Bcr 1 0.02 1.13 0.29
158 INT235962 Binding of Bcr and Trav6-3 1 0.00 1.12 0.29
159 INT202313 Gene_expression of PDGFB Positive_regulation of Positive_regulation of Pdgfrb 1 0.14 1 0.29
160 INT163903 Binding of EFNB1 and Src 1 0.03 0.56 0.29
161 INT266800 Dlst Positive_regulation of Localization of VEGFA 1 0.02 0.88 0.29
162 INT355038 NRP1 Negative_regulation of CKAP4 1 0.02 1.23 0.29
163 INT202314 Gene_expression of PDGFB Positive_regulation of Phosphorylation of Pdgfrb 1 0.14 1 0.29
164 INT254353 Binding of VEGFA and MMRN1 1 0.00 0.81 0.28
165 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27
166 INT320794 Binding of VEGFA and Flt4 4 0.08 3.04 0.27
167 INT103156 Tnf Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.94 0.27
168 INT287699 TNF Regulation of Binding of VEGFA 1 0.02 0.46 0.27
169 INT318551 Binding of VEGFA and Adamts1 1 0.13 1.13 0.27
170 INT285238 EGF Positive_regulation of VEGFA 1 0.01 1.55 0.27
171 INT355734 Pdgfb Regulation of Bdnf 1 0.22 1.5 0.27
172 INT224457 TNF Positive_regulation of Pdgfa 1 0.34 1.22 0.27
173 INT249493 Binding of Grin2b and Src 1 0.17 0.15 0.26
174 INT248318 RETN Regulation of VEGFA 1 0.00 0.43 0.26
175 INT109538 Lox Negative_regulation of Transcription of VEGFA 1 0.30 0.69 0.26
176 INT260423 IFNA1 Positive_regulation of Gene_expression of VEGFA 1 0.01 1.28 0.26
177 INT239570 Binding of PDGFC and AIS 1 0.04 0.9 0.26
178 INT254359 IL1B Positive_regulation of Localization of VEGFA 1 0.01 0.87 0.26
179 INT103152 TNF Positive_regulation of Positive_regulation of VEGFA 1 0.09 0.93 0.26
180 INT126886 Protein_catabolism of SP1 Negative_regulation of Gene_expression of VEGFA 1 0.03 0.49 0.26
181 INT126887 Protein_catabolism of SP4 Negative_regulation of Gene_expression of VEGFA 1 0.15 0.49 0.26
182 INT266803 Dlst Positive_regulation of VEGFA 1 0.01 0.96 0.25
183 INT109539 Lox Negative_regulation of VEGFA 1 0.40 0.68 0.25
184 INT348755 Plat Regulation of Gene_expression of Cldn5 1 0.10 0.45 0.25
185 INT145660 Zfp329 Positive_regulation of Gene_expression of VEGFA 1 0.00 0.51 0.25
186 INT241401 VEGFA Positive_regulation of Gene_expression of Gopc 1 0.11 0.85 0.25
187 INT332242 Binding of Egf and Pdgfa 1 0.07 0.97 0.25
188 INT256227 Binding of EDN1 and VEGFA 1 0.18 2.92 0.25
189 INT98631 Negative_regulation of VEGFA Positive_regulation of EGR1 1 0.44 0.18 0.24
190 INT235972 Negative_regulation of Binding of APC and Bcr 1 0.01 1.15 0.24
191 INT98630 VEGFA Positive_regulation of EGR1 1 0.52 0.18 0.24
192 INT235973 Binding of APC and Bcr 1 0.01 1.14 0.24
193 INT273055 Plat Positive_regulation of Gene_expression of Nos2 1 0.01 1.34 0.23
194 INT304323 VEGFA Positive_regulation of Gene_expression of Ptger2 1 0.27 0.16 0.23
195 INT118840 VEGFA Regulation of Positive_regulation of Mb 1 0.05 0.36 0.23
196 INT163403 VEGFA Positive_regulation of MMP2 1 0.52 0.13 0.23
197 INT323436 VEGFA Regulation of Kdr 1 0.03 0.77 0.23
198 INT304321 Ptger4 Positive_regulation of Gene_expression of VEGFA 1 0.27 0.59 0.23
199 INT304324 VEGFA Positive_regulation of Gene_expression of Ptger4 1 0.27 0.16 0.23
200 INT245866 Binding of VEGFA and Fgf1 1 0.07 0.52 0.22

Single Events

The table below shows the top 100 pain related interactions that have been reported for platelet-derived growth factor receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in platelet-derived growth factor receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
2 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
3 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
4 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53
5 INT101992 Localization of VEGFA 413 0.81 258.23 36.15
6 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52
7 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1
8 INT48692 Binding of VEGFA 345 0.48 210.3 21.31
9 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14
10 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03
11 INT96775 Gene_expression of Pdgfa 42 0.54 29.78 15.46
12 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89
13 INT82929 Gene_expression of Plat 58 0.78 26.96 13.85
14 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18
15 INT89842 Phosphorylation of Src 34 0.69 9.57 13.08
16 INT151168 Gene_expression of Pten 60 0.78 35.63 10.54
17 INT15449 Positive_regulation of Plat 32 0.69 12.76 9.71
18 INT65390 Positive_regulation of Plat 30 0.70 23.31 9.31
19 INT89845 Positive_regulation of Src 19 0.44 7.5 9.01
20 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39
21 INT10513 Gene_expression of Plat 44 0.76 19.49 7.17
22 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9
23 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63
24 INT124488 Positive_regulation of Gene_expression of Plat 14 0.70 5.46 6.52
25 INT17262 Negative_regulation of Plat 17 0.59 15.14 6.36
26 INT38595 Localization of BCAR1 8 0.73 2.9 6.25
27 INT111545 Phosphorylation of VEGFA 50 0.76 22.19 5.88
28 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78
29 INT124825 Transcription of Plat 8 0.70 3.15 5.68
30 INT100222 Binding of Src 9 0.26 5.41 5.37
31 INT96778 Positive_regulation of Pdgfa 22 0.46 12.7 5.31
32 INT107247 Regulation of Plat 10 0.44 7.21 5.14
33 INT89844 Positive_regulation of Phosphorylation of Src 10 0.43 4.71 4.95
34 INT100220 Negative_regulation of Src 13 0.41 6.37 4.93
35 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9
36 INT104668 Negative_regulation of Plat 27 0.49 17.18 4.83
37 INT99690 Negative_regulation of Positive_regulation of VEGFA 30 0.58 14.56 4.79
38 INT113161 Gene_expression of Jak2 50 0.77 42.52 4.76
39 INT1807 Negative_regulation of Bcar1 9 0.38 4.04 4.59
40 INT74531 Regulation of PDGFB 14 0.26 7.57 4.38
41 INT103153 Positive_regulation of Transcription of VEGFA 34 0.69 22.16 4.22
42 INT156097 Negative_regulation of Localization of VEGFA 70 0.58 34.96 4.17
43 INT3405 Gene_expression of BCAR1 14 0.71 8.89 4.02
44 INT153410 Negative_regulation of Jak2 5 0.59 10.71 3.98
45 INT96776 Positive_regulation of Gene_expression of Pdgfa 8 0.40 7.79 3.93
46 INT118835 Positive_regulation of Vegfa 18 0.59 11.2 3.91
47 INT276198 Positive_regulation of Pten 1 0.52 5.02 3.88
48 INT146350 Phosphorylation of Rgs14 1 0.80 0.79 3.77
49 INT122327 Regulation of Src 6 0.59 0.59 3.6
50 INT151171 Positive_regulation of Pten 20 0.55 13.3 3.54
51 INT70897 Positive_regulation of Gene_expression of PDGFB 15 0.57 13.04 3.52
52 INT96777 Localization of Pdgfa 12 0.79 5.86 3.52
53 INT70895 Localization of PDGFB 20 0.52 8.98 3.4
54 INT208291 Negative_regulation of Pten 2 0.44 5.42 3.36
55 INT22375 Localization of PDGFA 21 0.75 15.46 3.25
56 INT99687 Negative_regulation of Transcription of VEGFA 17 0.43 10.3 3.25
57 INT3403 Positive_regulation of BCAR1 18 0.63 18.95 3.23
58 INT111547 Negative_regulation of Phosphorylation of VEGFA 13 0.42 5.08 3.22
59 INT70885 Gene_expression of Pdgfb 48 0.67 42.27 3.19
60 INT10517 Localization of Plat 16 0.47 8.44 3.11
61 INT91173 Gene_expression of Pdgfrb 33 0.65 32.55 3.09
62 INT38594 Positive_regulation of Localization of BCAR1 3 0.63 0.44 3.07
63 INT137609 Localization of Vegfa 22 0.78 14.67 3.01
64 INT124489 Regulation of Gene_expression of Plat 5 0.45 0.48 2.87
65 INT271599 Phosphorylation of Pdgfa 1 0.11 2.55 2.81
66 INT184477 Negative_regulation of Pten 27 0.59 15.61 2.8
67 INT119383 Gene_expression of Pten 11 0.59 10.33 2.73
68 INT10512 Positive_regulation of Gene_expression of Plat 8 0.46 1.4 2.69
69 INT43719 Positive_regulation of Vegfa 21 0.69 5.15 2.64
70 INT172963 Negative_regulation of Pdgfa 11 0.21 12.94 2.64
71 INT87340 Negative_regulation of BCAR1 8 0.38 6.96 2.63
72 INT113160 Negative_regulation of Jak2 26 0.58 20.3 2.57
73 INT9374 Regulation of Plat 19 0.61 6.04 2.55
74 INT74527 Positive_regulation of PDGFB 14 0.38 13.31 2.54
75 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5
76 INT4435 Gene_expression of PIK3C2A 20 0.77 14.43 2.48
77 INT137908 Phosphorylation of Pdgfrb 14 0.81 8.44 2.45
78 INT61378 Positive_regulation of Bcar1 13 0.45 2.84 2.45
79 INT223080 Binding of Pdgfa 8 0.18 7.21 2.44
80 INT113164 Regulation of Regulation of VEGFA 6 0.36 5.96 2.43
81 INT124826 Positive_regulation of Transcription of Plat 3 0.68 0.33 2.38
82 INT184063 Positive_regulation of Jak2 17 0.69 10.97 2.37
83 INT123528 Negative_regulation of Gene_expression of Vegfa 10 0.57 7.08 2.31
84 INT29402 Gene_expression of Src 16 0.74 4.57 2.29
85 INT43723 Regulation of Vegfa 9 0.34 4.96 2.28
86 INT240113 Gene_expression of Nrp1 11 0.30 10.88 2.24
87 INT10514 Negative_regulation of Gene_expression of Plat 8 0.47 6.22 2.24
88 INT163545 Gene_expression of PDGFRB 39 0.78 25.5 2.2
89 INT224615 Negative_regulation of Gene_expression of Pten 7 0.59 2.99 2.09
90 INT276201 Phosphorylation of Pten 1 0.61 1.31 2.08
91 INT155234 Gene_expression of TXNIP 48 0.77 24.4 2.05
92 INT105247 Positive_regulation of Gene_expression of Vegfa 12 0.67 12.07 2.05
93 INT136818 Positive_regulation of Phosphorylation of VEGFA 4 0.46 0.81 2.02
94 INT107448 Positive_regulation of Jak2 8 0.50 5.33 1.98
95 INT204139 Positive_regulation of Gene_expression of BCAR1 1 0.23 0.9 1.96
96 INT137906 Positive_regulation of Phosphorylation of Pdgfrb 6 0.50 2.55 1.94
97 INT144020 Positive_regulation of Pdgfrb 30 0.69 24.8 1.92
98 INT122195 Regulation of Localization of VEGFA 13 0.57 10.61 1.92
99 INT52618 Positive_regulation of Pdgfc 3 0.33 0.82 1.9
100 INT249530 Positive_regulation of Positive_regulation of Src 3 0.28 1.32 1.9
101 INT99416 Negative_regulation of Bcar1 1 0.34 0.64 1.84
102 INT113676 Gene_expression of NRP1 22 0.72 10.81 1.71
103 INT118833 Positive_regulation of Gene_expression of Vegfa 11 0.65 8.14 1.7
104 INT23881 Gene_expression of Bcar1 8 0.52 2.48 1.69
105 INT12442 Localization of Vegfa 11 0.73 4.85 1.68
106 INT276171 Positive_regulation of Gene_expression of Pten 3 0.52 7.24 1.64
107 INT25445 Binding of Plat 7 0.41 12.75 1.63
108 INT126276 Regulation of Rgs14 1 0.39 0.71 1.63
109 INT105248 Negative_regulation of Vegfa 8 0.47 6.19 1.61
110 INT124824 Negative_regulation of Transcription of Plat 1 0.43 0.48 1.54
111 INT151169 Positive_regulation of Gene_expression of Pten 15 0.45 12.88 1.53
112 INT153409 Negative_regulation of Negative_regulation of Jak2 2 0.34 1.01 1.52
113 INT89116 Regulation of Positive_regulation of VEGFA 8 0.43 6.62 1.5
114 INT74528 Negative_regulation of PDGFB 11 0.40 10.34 1.48
115 INT74530 Transcription of PDGFB 7 0.65 4.56 1.47
116 INT235954 Gene_expression of Bcr 1 0.13 6.77 1.47
117 INT138699 Gene_expression of Pdgfc 5 0.30 3.32 1.46
118 INT228249 Binding of Pten 7 0.48 3.26 1.45
119 INT281470 Regulation of Gene_expression of Pten 4 0.39 1.13 1.42
120 INT276196 Positive_regulation of Phosphorylation of Pten 1 0.38 0.19 1.41
121 INT153515 Localization of Plat 10 0.77 4.21 1.4
122 INT109536 Negative_regulation of Vegfa 15 0.46 10.35 1.39
123 INT134041 Phosphorylation of Jak2 6 0.75 3.71 1.37
124 INT276181 Negative_regulation of Gene_expression of Pten 1 0.44 2.48 1.37
125 INT44529 Positive_regulation of Pdgfb 11 0.43 7.98 1.36
126 INT3404 Binding of BCAR1 10 0.33 7.97 1.33
127 INT239575 Regulation of PDGFC 1 0.07 4.93 1.3
128 INT95116 Negative_regulation of PDGFA 24 0.57 19.56 1.29
129 INT144019 Negative_regulation of Pdgfrb 21 0.58 14.93 1.26
130 INT192349 Negative_regulation of Gene_expression of PDGFB 5 0.31 2.64 1.25
131 INT153514 Positive_regulation of Localization of Plat 2 0.62 0.55 1.23
132 INT146351 Positive_regulation of Phosphorylation of Rgs14 1 0.45 0.27 1.23
133 INT171057 Gene_expression of PDGFC 7 0.15 5.84 1.22
134 INT61094 Gene_expression of Pdgfc 3 0.09 1.97 1.21
135 INT190014 Regulation of Pten 8 0.62 6.03 1.2
136 INT137607 Positive_regulation of Localization of Vegfa 7 0.49 3.72 1.18
137 INT188376 Negative_regulation of Gene_expression of Vegfa 5 0.30 5.29 1.18
138 INT116206 Transcription of Plat 3 0.67 1.52 1.18
139 INT70886 Positive_regulation of Gene_expression of Pdgfb 13 0.45 12.57 1.17
140 INT199315 Binding of Plat 8 0.34 7.02 1.14
141 INT210392 Regulation of PDGFA 10 0.36 11.41 1.12
142 INT249522 Positive_regulation of Binding of Src 1 0.22 0.68 1.12
143 INT124167 Regulation of Positive_regulation of Src 2 0.13 0.47 1.1
144 INT183820 Regulation of BCAR1 4 0.39 3.27 1.06
145 INT205912 Negative_regulation of Gene_expression of Jak2 8 0.42 5.1 1.04
146 INT116207 Positive_regulation of Transcription of Plat 1 0.49 0.66 1.02
147 INT1940 Localization of PIK3C2A 8 0.78 7.28 1.01
148 INT112717 Negative_regulation of Binding of VEGFA 21 0.56 11.07 0.99
149 INT2991 Regulation of PIK3C2A 6 0.60 4.46 0.99
150 INT126672 Binding of Bcar1 7 0.20 2.67 0.98
151 INT126279 Gene_expression of Rgs14 1 0.67 0.34 0.98
152 INT96774 Positive_regulation of Localization of Pdgfa 3 0.69 1.21 0.95
153 INT204136 Regulation of Gene_expression of BCAR1 2 0.21 0.62 0.93
154 INT100221 Negative_regulation of Phosphorylation of Src 2 0.24 0.74 0.93
155 INT169336 Binding of Jak2 2 0.42 1.31 0.93
156 INT134040 Regulation of Jak2 3 0.41 1.07 0.92
157 INT46485 Positive_regulation of Pdgfc 3 0.18 2.74 0.92
158 INT188317 Positive_regulation of Gene_expression of PDGFA 15 0.46 12.7 0.91
159 INT271598 Negative_regulation of Phosphorylation of Pdgfa 1 0.05 0.77 0.88
160 INT184027 Phosphorylation of Jak2 6 0.82 2.58 0.87
161 INT271597 Regulation of Gene_expression of Pdgfa 1 0.05 0.81 0.87
162 INT17807 Positive_regulation of PDGFC 4 0.06 3.28 0.86
163 INT134037 Positive_regulation of Phosphorylation of Jak2 1 0.46 0.25 0.86
164 INT149291 Negative_regulation of NRP1 5 0.40 2.64 0.84
165 INT276177 Regulation of Gene_expression of Pten 1 0.34 1.51 0.84
166 INT211488 Regulation of Binding of VEGFA 5 0.43 3.72 0.83
167 INT119102 Gene_expression of PDGFRA 13 0.75 11.99 0.81
168 INT173082 Positive_regulation of Binding of VEGFA 20 0.48 11.16 0.79
169 INT171096 Transcription of PDGFA 5 0.47 4.42 0.79
170 INT54940 Positive_regulation of Gab1 1 0.04 0.48 0.79
171 INT237408 Positive_regulation of Positive_regulation of Jak2 1 0.28 1.56 0.79
172 INT239574 Binding of PDGFC 1 0.04 3.29 0.79
173 INT149298 Protein_catabolism of NRP1 2 0.82 1.52 0.77
174 INT249506 Regulation of Phosphorylation of Src 1 0.13 0.48 0.77
175 INT95118 Negative_regulation of Gene_expression of PDGFA 4 0.54 5.03 0.76
176 INT11709 Positive_regulation of Gene_expression of PIK3C2A 2 0.49 1.88 0.74
177 INT207285 Positive_regulation of Gene_expression of TXNIP 1 0.69 9.53 0.73
178 INT164756 Negative_regulation of PDGFRB 32 0.57 21.69 0.72
179 INT143445 Protein_catabolism of VEGFA 12 0.85 4.14 0.72
180 INT12443 Regulation of Localization of Vegfa 2 0.20 0 0.72
181 INT139205 Binding of NRP1 27 0.45 4.34 0.71
182 INT202307 Regulation of Gene_expression of PDGFB 2 0.26 1.24 0.71
183 INT3536 Positive_regulation of Nrp1 2 0.19 0.93 0.7
184 INT265800 Localization of NRP1 14 0.75 3.66 0.69
185 INT196155 Binding of Nrp1 5 0.16 2.38 0.69
186 INT171364 Localization of Pdgfrb 6 0.37 4.98 0.68
187 INT91172 Positive_regulation of Gene_expression of Pdgfrb 4 0.38 2.83 0.68
188 INT276199 Binding of Pten 2 0.30 0.4 0.67
189 INT171380 Positive_regulation of Localization of Pdgfrb 1 0.21 0.48 0.66
190 INT260823 Positive_regulation of Gene_expression of Nrp1 3 0.19 2.14 0.65
191 INT340625 Protein_catabolism of Vegfa 1 0.05 1.61 0.64
192 INT210390 Binding of PDGFA 12 0.36 6.78 0.63
193 INT174868 Regulation of Negative_regulation of VEGFA 4 0.43 4.51 0.63
194 INT276179 Regulation of Pten 1 0.46 0.81 0.63
195 INT74529 Binding of PDGFB 13 0.36 7.41 0.62
196 INT285478 Negative_regulation of Rgs14 1 0.27 1.25 0.6
197 INT277699 Gene_expression of Pdgfb 5 0.20 4.84 0.59
198 INT54939 Regulation of Gab1 1 0.04 0.39 0.59
199 INT235996 Negative_regulation of Gene_expression of Src 3 0.09 1.29 0.58
200 INT174873 Regulation of Transcription of VEGFA 8 0.43 3.71 0.55
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