GO:0048013

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Name ephrin receptor signaling pathway
Categary Process
Go Slim No
Go Link GO:0048013
Unique Molecular Interactions 489
Total Molecular Interactions 618
Total Single Events 6170
Pain Genes Associated 36

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for ephrin receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for ephrin receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT92738 Binding of Ephb1 and Tcas1 1 0.00 0.43 2.67
2 INT121742 Prkcg Positive_regulation of Ephb1 3 0.49 0.99 2.6
3 INT128044 Bdnf Positive_regulation of Ephb1 2 0.31 1.89 2.57
4 INT121746 Prkaca Positive_regulation of Ephb1 2 0.23 0.92 2.35
5 INT156623 Umod Regulation of Phosphorylation of Ephb1 1 0.05 0.33 2.27
6 INT344386 Efnb1 Positive_regulation of Phosphorylation of Ephb2 1 0.15 2.85 2.13
7 INT153533 NMS Regulation of Gene_expression of Ephb1 1 0.48 3.96 1.93
8 INT95405 Trib3 Positive_regulation of Phosphorylation of Ephb1 3 0.08 1.33 1.89
9 INT112517 Binding of Ephb1 and Prkaca 3 0.18 0.58 1.85
10 INT162992 Binding of Ephb1 and Ppm1e 1 0.03 0.25 1.77
11 INT142899 Chn1 Negative_regulation of Positive_regulation of NOS1 1 0.01 1.07 1.75
12 INT249483 Binding of Ephb1 and Efnb2 1 0.02 2.35 1.66
13 INT131575 Grin1 Negative_regulation of Positive_regulation of Ephb1 1 0.28 0.31 1.58
14 INT131574 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Creb1 1 0.41 0.33 1.58
15 INT158778 Ptges3l1 Regulation of Ephb1 1 0.06 0.09 1.53
16 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
17 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
18 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
19 INT256299 Binding of Efnb1 and Ephb1 1 0.02 1.22 1.42
20 INT249494 Binding of Ephb1 and Efnb1 1 0.01 1.34 1.4
21 INT261483 Binding of Ephb1 and Trpv1 1 0.39 1.37 1.37
22 INT95406 Trib3 Positive_regulation of Ephb1 2 0.08 0.96 1.29
23 INT154518 Binding of Ephb6 and Grin2b 1 0.21 0.24 1.28
24 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23
25 INT121729 Negative_regulation of Ngf Positive_regulation of Ephb1 1 0.24 0.69 1.22
26 INT256298 Binding of Creb1 and Ephb1 1 0.16 1.27 1.22
27 INT121724 Ngf Positive_regulation of Ephb1 1 0.40 0.68 1.21
28 INT334351 Bdnf Regulation of Positive_regulation of Ephb1 1 0.18 1.27 1.2
29 INT125284 FSCN1 Positive_regulation of Positive_regulation of EPHB2 1 0.04 0.4 1.14
30 INT249481 Positive_regulation of Binding of Ephb1 and Efnb2 1 0.03 1.36 1.12
31 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12
32 INT269190 Positive_regulation of Ephb1 Positive_regulation of Ceacam3 1 0.03 0.66 1.12
33 INT256294 Binding of Grin2b and Ephb1 1 0.28 1.11 1.08
34 INT156462 Creb1 Regulation of Ephb1 1 0.29 0 1.07
35 INT269192 Ephb1 Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
36 INT121727 Pik3cb Positive_regulation of Ephb1 1 0.49 0.6 1.06
37 INT346835 Gene_expression of Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.27 1.07 1.03
38 INT121743 Negative_regulation of Src Negative_regulation of Ephb1 1 0.27 0 1.02
39 INT240455 Ephb1 Positive_regulation of Positive_regulation of Prkaca 1 0.22 0.63 1.01
40 INT344389 Ephb2 Positive_regulation of Phosphorylation of Grin2b 1 0.16 1.46 0.98
41 INT121744 Src Positive_regulation of Positive_regulation of Ephb1 1 0.35 0 0.96
42 INT138072 Chn1 Positive_regulation of Oprl1 1 0.42 1.02 0.95
43 INT137921 VEGFA Positive_regulation of Ephb2 1 0.03 0 0.93
44 INT116930 OPRK1 Positive_regulation of Binding of PTK2 1 0.28 0.35 0.93
45 INT80718 Trpv3 Negative_regulation of Chn1 1 0.01 0.7 0.92
46 INT341371 CRX Positive_regulation of Gene_expression of Ephb1 1 0.02 0.99 0.9
47 INT121745 Tacr1 Negative_regulation of Positive_regulation of Ephb1 1 0.04 0 0.87
48 INT134993 P2rx6 Regulation of Ephb1 1 0.20 1.27 0.87
49 INT249491 Efnb2 Positive_regulation of Phosphorylation of Src 1 0.01 0.5 0.87
50 INT196578 Ephb1 Positive_regulation of Phosphorylation of Mapk9 1 0.13 0.5 0.85
51 INT261480 Negative_regulation of Trib3 Positive_regulation of Ephb1 1 0.04 0.8 0.84
52 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
53 INT261479 Fig4 Positive_regulation of Ephb1 1 0.07 0.79 0.83
54 INT334358 Rvm Positive_regulation of Ephb1 1 0.17 0.98 0.82
55 INT334359 Negative_regulation of Rvm Positive_regulation of Ephb1 1 0.16 0.99 0.82
56 INT128042 Bdnf Positive_regulation of Phosphorylation of Ephb1 1 0.22 0.2 0.8
57 INT240456 Ephb1 Regulation of Prkcg 1 0.19 0.51 0.79
58 INT117971 Cd8a Negative_regulation of Positive_regulation of Ephb1 1 0.02 0.98 0.79
59 INT240454 Ephb1 Regulation of Prkaca 1 0.14 0.51 0.79
60 INT162995 Positive_regulation of Binding of Ephb1 and Ppm1e 1 0.04 0.06 0.74
61 INT328625 NPL Regulation of Phosphorylation of Ephb1 1 0.04 0.42 0.7
62 INT154989 Phax Positive_regulation of Positive_regulation of Ephb1 1 0.22 0.92 0.69
63 INT344387 Efnb2 Positive_regulation of Phosphorylation of Tyr 1 0.01 1.05 0.66
64 INT112515 Binding of Ephb1 and Trib3 1 0.06 0.41 0.65
65 INT111936 Binding of PIK3CA and PTK2 1 0.19 0.67 0.65
66 INT111937 Binding of PIK3CG and PTK2 1 0.08 0.67 0.64
67 INT83804 Binding of EPHB3 and DRGX 1 0.00 0.62 0.62
68 INT128817 Ephb1 Negative_regulation of Gene_expression of Nos2 1 0.16 0.37 0.61
69 INT128814 Ephb1 Negative_regulation of Gene_expression of Il1b 1 0.02 0.37 0.61
70 INT261482 Pik3cb Positive_regulation of Phosphorylation of Ephb1 1 0.23 0.67 0.58
71 INT261485 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Ephb1 1 0.05 0.12 0.56
72 INT261478 Positive_regulation of Ephb1 Regulation of Gene_expression of Egr1 1 0.10 0.23 0.55
73 INT312746 Ephb1 Positive_regulation of Localization of Ltp 1 0.05 0.07 0.55
74 INT256296 Efnb1 Positive_regulation of Ephb1 1 0.03 0.66 0.54
75 INT249497 Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.02 0.51 0.54
76 INT132372 Lgals1 Positive_regulation of Ephb1 1 0.37 0.25 0.54
77 INT249499 Ephb1 Positive_regulation of Efnb2 1 0.04 0.95 0.54
78 INT249479 Binding of Ephb1 and Grin2b 1 0.29 0.37 0.54
79 INT274935 Ltp Positive_regulation of Localization of Ephb6 1 0.33 0 0.52
80 INT249536 Binding of EPHA1 and Efnb2 1 0.02 0.28 0.52
81 INT120383 PRKCD Positive_regulation of Localization of EPHB2 1 0.29 0.42 0.52
82 INT193554 Ntrk2 Positive_regulation of Positive_regulation of Ephb1 1 0.01 0.73 0.52
83 INT274938 Ltp Positive_regulation of Localization of Ephb2 1 0.25 0 0.52
84 INT104960 Ephb1 Regulation of Positive_regulation of Mapk14 1 0.15 0.42 0.5
85 INT104961 Mapk14 Regulation of Positive_regulation of Ephb1 1 0.15 0.42 0.5
86 INT153534 Binding of Ephb1 and NMS 1 0.29 1.13 0.5
87 INT108329 EGF Positive_regulation of Phosphorylation of EPHB2 4 0.48 3.96 0.48
88 INT116932 PTK2 Negative_regulation of Positive_regulation of MAPK8 1 0.35 0.17 0.48
89 INT116935 Positive_regulation of OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.47
90 INT116939 OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.46
91 INT249486 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Grin2b 1 0.33 0.4 0.46
92 INT95404 Map3k1 Positive_regulation of Phosphorylation of Ephb1 1 0.12 0.16 0.46
93 INT95408 Map3k1 Positive_regulation of Ephb1 1 0.12 0.16 0.46
94 INT273235 Binding of Cdk5 and Cdk5r1 1 0.24 6.06 0.46
95 INT116928 PTK2 Positive_regulation of JUN 1 0.20 0.15 0.46
96 INT117776 Binding of Ptk2 and Regulation of Phosphorylation of Ddr1 1 0.10 0.17 0.46
97 INT149006 RPL7AP5 Negative_regulation of Phosphorylation of Ephb1 1 0.00 0.22 0.45
98 INT127392 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Grin1 1 0.08 0.71 0.45
99 INT127393 Negative_regulation of Ephb1 Negative_regulation of Positive_regulation of Nfkb1 1 0.10 0.7 0.45
100 INT127394 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Grin2a 1 0.01 0.71 0.45
101 INT127391 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Elk1 1 0.08 0.71 0.45
102 INT127395 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Tacr1 1 0.07 0.71 0.45
103 INT127390 Negative_regulation of Ephb1 Negative_regulation of Phosphorylation of Elk1 1 0.08 0.7 0.44
104 INT149005 RPL7AP5 Negative_regulation of Ephb1 1 0.00 0.21 0.44
105 INT278950 MAPK8 Negative_regulation of Localization of EPHB2 1 0.25 0.47 0.43
106 INT265647 Binding of Ephb1 and Mapk1 1 0.00 1.48 0.43
107 INT278964 MAPK14 Negative_regulation of Localization of EPHB2 1 0.15 0.47 0.43
108 INT95403 Ephb1 Regulation of Positive_regulation of Trib3 1 0.07 0.19 0.41
109 INT300652 Ephb6 Regulation of Gene_expression of Cxcl10 1 0.01 0.59 0.41
110 INT118285 Binding of EFNA1 and HLA-B 1 0.03 0.29 0.37
111 INT304501 Binding of Ephb1 and Mapk1 1 0.18 0.69 0.36
112 INT274936 Ephb2 Regulation of Gene_expression of Fos 1 0.15 0 0.36
113 INT274941 Ephb2 Regulation of Phosphorylation of Mapk1 1 0.19 0 0.36
114 INT224284 BDNF Positive_regulation of Ephb1 1 0.36 0.22 0.36
115 INT274937 Ephb2 Regulation of Phosphorylation of Creb1 1 0.21 0 0.36
116 INT274933 Ephb2 Regulation of Phosphorylation of Camk2a 1 0.29 0 0.36
117 INT270220 Negative_regulation of Ephb1 Negative_regulation of Positive_regulation of Pla2g4a 1 0.13 1 0.36
118 INT309151 Dlat Positive_regulation of Positive_regulation of Ephb1 1 0.02 0.57 0.33
119 INT342882 Positive_regulation of Ephb1 Regulation of Gene_expression of Pdyn 1 0.01 0.36 0.33
120 INT249490 Phosphorylation of Ephb2 Positive_regulation of Src 1 0.17 0.15 0.33
121 INT309128 Edc4 Positive_regulation of Positive_regulation of Ephb1 1 0.01 0.58 0.33
122 INT339645 Binding of Cdk5r1 and Ebi3 1 0.01 0.78 0.31
123 INT249480 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Src 1 0.22 0.23 0.31
124 INT341777 SLC6A4 Regulation of EPHB1 1 0.02 0.96 0.3
125 INT135014 Binding of Ephb1 and Cabin1 1 0.09 0.32 0.3
126 INT298996 Il18 Positive_regulation of Gene_expression of Cdk5r1 1 0.03 1.65 0.29
127 INT295360 Ntn1 Positive_regulation of Ptk2 1 0.09 0.51 0.29
128 INT299011 Il18 Positive_regulation of Transcription of Cdk5r1 1 0.03 1.65 0.29
129 INT218936 Dusp1 Negative_regulation of Ephb1 2 0.03 0.89 0.28
130 INT247949 Cdk5r1 Positive_regulation of Cdk5 1 0.26 1.12 0.28
131 INT218934 Cyp3a23/3a1 Negative_regulation of Ephb1 1 0.01 0.95 0.28
132 INT309121 Positive_regulation of Gsdmc Positive_regulation of Positive_regulation of Ephb1 1 0.01 0.76 0.28
133 INT132373 Ephb1 Positive_regulation of Positive_regulation of Nfkb1 1 0.18 0.12 0.28
134 INT132364 Ephb1 Positive_regulation of Nfkb1 1 0.07 0.11 0.27
135 INT309134 Edc4 Positive_regulation of Ephb1 1 0.01 0.54 0.27
136 INT316929 Pde5a Regulation of Ephb1 1 0.03 0.17 0.27
137 INT132370 Mapk8 Positive_regulation of Ephb1 1 0.15 0.12 0.27
138 INT309133 Dlat Positive_regulation of Ephb1 1 0.02 0.54 0.27
139 INT274940 Ephb2 Negative_regulation of Gene_expression of Fos 1 0.15 0.07 0.27
140 INT179928 Binding of Ephb1 and Mapk8 1 0.11 0.91 0.26
141 INT149947 Ephb1 Positive_regulation of Prkcg 1 0.27 0.07 0.26
142 INT274939 Binding of Dlg4 and Ephb6 1 0.12 0 0.25
143 INT274942 Binding of Dlg1 and Ephb6 1 0.05 0 0.25
144 INT149948 Ephb1 Negative_regulation of Phosphorylation of Map2 1 0.37 0.07 0.25
145 INT273232 Negative_regulation of Binding of Cdk5 and Cdk5r1 1 0.28 3.16 0.23
146 INT283858 Binding of PTK2 and APOA5 1 0.00 0.67 0.21
147 INT157692 Cck Positive_regulation of Ephb1 1 0.26 0 0.21
148 INT326831 Cdk5r2 Positive_regulation of Binding of Cdk5r1 1 0.01 0.95 0.21
149 INT178086 Binding of EDNRA and PTK2 1 0.07 0.82 0.2
150 INT269446 Binding of EPHA3 and HHIP 1 0.01 0 0.2
151 INT221955 Binding of ELAVL1 and CDK5R1 1 0.01 0.93 0.19
152 INT221956 CDK5R1 Regulation of Positive_regulation of CDK5 1 0.21 0.62 0.19
153 INT338898 Binding of PECAM1 and PTPN11 1 0.04 0.38 0.19
154 INT222025 Gpx3 Regulation of EPHB2 1 0.01 1.41 0.18
155 INT289251 Ptpn11 Regulation of Il6 1 0.09 0.86 0.18
156 INT178092 EDN3 Positive_regulation of PTK2 1 0.01 1.02 0.17
157 INT333299 Zic2 Regulation of Transcription of Ephb1 1 0.50 0.09 0.17
158 INT108663 Lrpap1 Negative_regulation of Positive_regulation of Ephb1 1 0.11 0.28 0.17
159 INT108667 ras Negative_regulation of Positive_regulation of Ephb1 1 0.02 0.28 0.17
160 INT178073 EDN1 Positive_regulation of PTK2 1 0.03 1.02 0.17
161 INT261477 Egf Positive_regulation of Positive_regulation of Ephb1 1 0.37 0.21 0.17
162 INT164791 Cdk5r1 Positive_regulation of Cdk5 1 0.30 0.25 0.17
163 INT164790 Cdk5r1 Positive_regulation of Trib3 1 0.02 0.25 0.17
164 INT299001 Il18 Positive_regulation of Cdk5r1 1 0.03 0.36 0.17
165 INT222877 Chrm2 Negative_regulation of EPHB2 1 0.05 0.66 0.17
166 INT291354 CXCL12 Positive_regulation of EPHB2 1 0.42 2.02 0.16
167 INT193546 Il1b Positive_regulation of Ephb1 1 0.12 0.35 0.16
168 INT194667 EPHB6 Positive_regulation of MAPK1 1 0.12 0.54 0.16
169 INT179931 Ephb1 Regulation of Gene_expression of Mmp9 1 0.04 0.48 0.15
170 INT193550 Ephb1 Positive_regulation of Gene_expression of Bdnf 1 0.29 0.3 0.14
171 INT147727 Phosphorylation of PTK2 Regulation of Positive_regulation of RAC1 1 0.34 0.32 0.14
172 INT287890 THEMIS Regulation of Gene_expression of EPHB2 1 0.00 0.87 0.14
173 INT287883 FOS Regulation of Gene_expression of EPHB2 1 0.01 0.87 0.14
174 INT147726 Phosphorylation of PTK2 Regulation of Positive_regulation of PIK3CA 1 0.09 0.32 0.14
175 INT193553 Mtpn Positive_regulation of Ephb1 1 0.04 0.34 0.13
176 INT326249 Prkcg Positive_regulation of EPHB2 1 0.06 0.63 0.13
177 INT326252 EPHB2 Positive_regulation of ras 1 0.03 0.62 0.13
178 INT291349 CXCR4 Positive_regulation of EPHB2 1 0.42 1.87 0.13
179 INT108330 EGF Negative_regulation of EPHB2 1 0.41 1.15 0.13
180 INT193548 Gdnf Positive_regulation of Ephb1 1 0.40 0.34 0.13
181 INT214958 Ss18 Regulation of Rims1 1 0.15 0 0.12
182 INT332687 Ros1 Positive_regulation of Crk 1 0.17 0.77 0.12
183 INT249495 Binding of Grin2b and Efnb2 1 0.02 0.05 0.11
184 INT221958 CDK5R1 Positive_regulation of Positive_regulation of CDK5 1 0.36 0.38 0.1
185 INT327405 Lox Positive_regulation of Ptk2 1 0.42 1.3 0.1
186 INT128696 Il1a Positive_regulation of Phosphorylation of Ephb1 1 0.26 0.82 0.1
187 INT221959 Binding of CDK5 and CDK5R1 1 0.28 0.53 0.1
188 INT201748 Car2 Positive_regulation of Cdk5r1 1 0.00 0.67 0.09
189 INT224021 PIK3CG Negative_regulation of EPHB2 1 0.03 0.5 0.09
190 INT178089 Binding of EDNRA and Positive_regulation of PTK2 1 0.09 0.74 0.09
191 INT224020 MAPK1 Negative_regulation of EPHB2 1 0.08 0.56 0.09
192 INT194728 Binding of EPHB6 and Positive_regulation of MAPK1 1 0.12 0.26 0.08
193 INT221258 Negative_regulation of Binding of VDAC1 and Crk 1 0.00 0.22 0.08
194 INT249126 Binding of Ephb1 and Mtor 1 0.02 0 0.08
195 INT310564 Positive_regulation of Ephb1 Regulation of Stat3 1 0.03 0.17 0.08
196 INT109864 Negative_regulation of ras Positive_regulation of Ephb1 1 0.01 0.37 0.08
197 INT355582 VEGFA Regulation of Positive_regulation of PTK2 1 0.05 1.46 0.08
198 INT221255 Binding of VDAC1 and Crk 1 0.00 0.22 0.08
199 INT109865 ras Positive_regulation of Ephb1 1 0.01 0.37 0.08
200 INT212078 Eno2 Regulation of Localization of EPHB6 1 0.03 0.52 0.07

Single Events

The table below shows the top 100 pain related interactions that have been reported for ephrin receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in ephrin receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14
2 INT63934 Phosphorylation of Ephb1 377 0.82 150.52 188.66
3 INT48923 Gene_expression of Ephb1 211 0.77 106.23 109.9
4 INT63936 Positive_regulation of Phosphorylation of Ephb1 131 0.70 49.38 73.16
5 INT84495 Positive_regulation of Positive_regulation of Ephb1 85 0.70 46.12 54.11
6 INT48920 Negative_regulation of Ephb1 107 0.57 43.6 51.02
7 INT48929 Regulation of Ephb1 71 0.62 24.42 42.11
8 INT63933 Negative_regulation of Positive_regulation of Ephb1 53 0.58 22.83 33.43
9 INT63935 Positive_regulation of Gene_expression of Ephb1 52 0.61 24.3 33.05
10 INT84494 Negative_regulation of Phosphorylation of Ephb1 44 0.59 22.34 28.68
11 INT123035 Gene_expression of Ephb1 38 0.78 28.84 27.32
12 INT109379 Regulation of Phosphorylation of Ephb1 22 0.59 12.58 18.84
13 INT92733 Negative_regulation of Ephb1 19 0.51 8.56 17.72
14 INT256282 Gene_expression of Efnb2 3 0.76 17.61 16.41
15 INT128921 Negative_regulation of Gene_expression of Ephb1 18 0.49 9.54 14.93
16 INT84496 Regulation of Positive_regulation of Ephb1 18 0.61 10.16 13.92
17 INT135909 Positive_regulation of Ephb1 11 0.70 8.94 11.78
18 INT150285 Positive_regulation of Efnb1 6 0.29 10.22 11.44
19 INT87650 Positive_regulation of EPHB2 49 0.67 22.77 8.25
20 INT108336 Phosphorylation of EPHB2 41 0.80 22.25 8.21
21 INT127853 Localization of Ephb1 20 0.74 5.47 7.96
22 INT147715 Regulation of Gene_expression of Ephb1 6 0.62 5.26 7.49
23 INT157430 Gene_expression of Ephb6 18 0.70 8.13 7.14
24 INT92734 Binding of Ephb1 5 0.37 3.86 7.02
25 INT125143 Gene_expression of EPHB2 40 0.71 13.27 6.97
26 INT150287 Positive_regulation of Ephb2 5 0.33 5.54 6.9
27 INT48922 Regulation of Gene_expression of Ephb1 14 0.50 5.73 6.47
28 INT60161 Gene_expression of EPHA3 43 0.75 3.66 6.25
29 INT181053 Regulation of Ephb1 6 0.45 6.17 5.77
30 INT145188 Gene_expression of Efnb1 4 0.32 6.07 5.74
31 INT83597 Phosphorylation of Ptk2 20 0.82 3.24 5.7
32 INT134468 Gene_expression of Cdk5r1 26 0.48 27.09 5.2
33 INT126847 Binding of Ephb1 15 0.46 6.47 5.17
34 INT108342 Negative_regulation of EPHB2 18 0.57 9.48 4.46
35 INT87345 Phosphorylation of PTK2 110 0.82 59.39 4.28
36 INT109219 Negative_regulation of Cdk5r1 5 0.43 1.22 4.25
37 INT346828 Regulation of Efnb2 1 0.61 8.57 3.81
38 INT138070 Gene_expression of Chn1 1 0.56 4.05 3.79
39 INT117773 Positive_regulation of Phosphorylation of Ptk2 9 0.69 0.89 3.71
40 INT346826 Positive_regulation of Gene_expression of Efnb2 1 0.46 3.88 3.71
41 INT117836 Gene_expression of EPHB3 13 0.29 0.62 3.44
42 INT137907 Phosphorylation of Ephb2 2 0.61 2.78 2.96
43 INT346829 Negative_regulation of Efnb2 1 0.42 5.08 2.94
44 INT108338 Positive_regulation of Phosphorylation of EPHB2 13 0.67 5.42 2.92
45 INT145187 Gene_expression of Efnb2 4 0.22 3.43 2.92
46 INT138068 Positive_regulation of Chn1 2 0.50 2.45 2.87
47 INT138067 Regulation of Chn1 2 0.20 2.43 2.82
48 INT256286 Negative_regulation of Gene_expression of Ephb1 1 0.43 3.36 2.78
49 INT157429 Negative_regulation of Ephb6 3 0.35 2.17 2.77
50 INT201632 Positive_regulation of Cdk5r1 20 0.40 21.6 2.75
51 INT150286 Gene_expression of Ephb2 3 0.39 2.57 2.74
52 INT269377 Positive_regulation of EPHA3 22 0.18 0.97 2.55
53 INT150288 Positive_regulation of Gene_expression of Efnb1 2 0.21 2.73 2.53
54 INT193319 Positive_regulation of Efnb2 2 0.49 2.1 2.47
55 INT346831 Regulation of Gene_expression of Efnb2 1 0.44 2.83 2.47
56 INT101603 Positive_regulation of Cdk5r1 4 0.56 1.12 2.35
57 INT346834 Phosphorylation of Efnb2 1 0.62 1.54 2.19
58 INT183159 Gene_expression of Epha1 3 0.25 3.15 2.17
59 INT116077 Positive_regulation of Positive_regulation of EPHB2 4 0.67 2.32 2.13
60 INT154517 Localization of Ephb6 4 0.67 0.51 1.92
61 INT154516 Binding of Ephb6 2 0.33 0.24 1.92
62 INT150284 Negative_regulation of Positive_regulation of Efnb1 1 0.18 1.53 1.86
63 INT83596 Gene_expression of Ptk2 6 0.76 2.22 1.84
64 INT154515 Localization of Ephb2 2 0.73 0.17 1.77
65 INT145184 Positive_regulation of Gene_expression of Efnb2 3 0.20 1.94 1.69
66 INT101599 Gene_expression of Cdk5r1 5 0.63 1.27 1.68
67 INT116110 Positive_regulation of PTK2 20 0.66 10.53 1.64
68 INT98788 Negative_regulation of EPHB1 11 0.37 3.65 1.64
69 INT158773 Positive_regulation of Localization of Ephb1 1 0.34 0.08 1.64
70 INT206471 Positive_regulation of Ptk2 34 0.51 25.75 1.61
71 INT117717 Negative_regulation of Regulation of Ephb1 3 0.41 0.61 1.61
72 INT142898 Positive_regulation of Regulation of Chn1 1 0.25 1.02 1.57
73 INT118286 Binding of EFNA1 3 0.21 4.95 1.55
74 INT147713 Localization of Ephb1 1 0.70 0 1.54
75 INT111946 Positive_regulation of Phosphorylation of PTK2 8 0.66 11.5 1.53
76 INT135907 Negative_regulation of Positive_regulation of Ephb1 1 0.38 0.42 1.51
77 INT135908 Regulation of Negative_regulation of Ephb1 1 0.24 0.4 1.49
78 INT101601 Regulation of Cdk5r1 3 0.50 1.2 1.46
79 INT111162 Negative_regulation of EFNA1 2 0.03 2.78 1.45
80 INT135906 Positive_regulation of Positive_regulation of Ephb1 1 0.44 0.38 1.45
81 INT212466 Regulation of EPHB1 7 0.37 5.72 1.42
82 INT224501 Positive_regulation of Gene_expression of EPHB2 9 0.49 4.29 1.39
83 INT131115 Regulation of Phosphorylation of Ptk2 2 0.61 0.3 1.34
84 INT114969 Gene_expression of CDK5R1 3 0.75 11.24 1.33
85 INT168312 Positive_regulation of Gene_expression of EPHA3 8 0.49 0.97 1.32
86 INT145183 Negative_regulation of Gene_expression of Efnb2 2 0.17 1.51 1.31
87 INT109924 Localization of EPHB2 6 0.73 2.07 1.28
88 INT138069 Negative_regulation of Gene_expression of Chn1 1 0.31 1.38 1.28
89 INT117719 Transcription of Ephb1 2 0.44 0.06 1.25
90 INT344370 Phosphorylation of Ephb6 1 0.31 1.67 1.25
91 INT119827 Gene_expression of PTPN11 31 0.75 24.21 1.22
92 INT138071 Regulation of Gene_expression of Chn1 1 0.20 1.31 1.2
93 INT87343 Negative_regulation of Phosphorylation of PTK2 34 0.59 18.38 1.19
94 INT166274 Gene_expression of EPHB1 14 0.55 8.2 1.19
95 INT83805 Binding of EPHB3 1 0.00 1.15 1.19
96 INT87346 Binding of PTK2 6 0.37 4.03 1.18
97 INT108334 Negative_regulation of Phosphorylation of EPHB2 4 0.57 2.27 1.16
98 INT138783 Positive_regulation of Gene_expression of Cdk5r1 2 0.38 0.68 1.15
99 INT203890 Positive_regulation of Gene_expression of Cdk5r1 9 0.40 9.13 1.11
100 INT346832 Negative_regulation of Gene_expression of Efnb2 1 0.42 0.75 1.09
101 INT87342 Regulation of Phosphorylation of PTK2 3 0.59 5.7 1.05
102 INT240461 Regulation of Negative_regulation of Ephb1 4 0.37 1.66 0.96
103 INT109221 Positive_regulation of Negative_regulation of Cdk5r1 1 0.37 0.15 0.95
104 INT346827 Binding of Efnb2 1 0.37 1.56 0.91
105 INT87344 Gene_expression of PTK2 90 0.78 59.03 0.87
106 INT131113 Negative_regulation of Ptk2 3 0.58 0.17 0.85
107 INT249508 Phosphorylation of Efnb2 1 0.04 0.5 0.84
108 INT147716 Negative_regulation of Localization of Ephb1 1 0.51 0 0.84
109 INT269642 Binding of EPHA3 4 0.10 0.22 0.8
110 INT77663 Positive_regulation of CDK5R1 3 0.67 0.43 0.79
111 INT134207 Gene_expression of Ptk2 56 0.73 31.97 0.78
112 INT109912 Positive_regulation of Localization of EPHB2 2 0.49 0.56 0.77
113 INT87341 Regulation of Gene_expression of PTK2 2 0.62 8.34 0.77
114 INT97782 Protein_catabolism of Ephb1 5 0.86 1.27 0.76
115 INT273220 Positive_regulation of Positive_regulation of Cdk5r1 4 0.40 5.3 0.75
116 INT42722 Negative_regulation of Ptpn11 1 0.21 0 0.71
117 INT249511 Binding of Efnb1 1 0.01 0.67 0.7
118 INT119836 Positive_regulation of Gene_expression of PTPN11 5 0.67 3.44 0.69
119 INT274918 Negative_regulation of Gene_expression of Ephb6 1 0.38 0 0.69
120 INT111161 Positive_regulation of EFNA1 6 0.40 4.62 0.68
121 INT134472 Binding of Cdk5r1 4 0.26 4.25 0.65
122 INT70056 Gene_expression of Chn1 3 0.32 0.47 0.63
123 INT77662 Regulation of CDK5R1 2 0.60 1.93 0.63
124 INT249518 Binding of Efnb2 1 0.02 0.59 0.63
125 INT127854 Regulation of Localization of Ephb1 1 0.25 0.69 0.62
126 INT221978 Regulation of Gene_expression of CDK5R1 1 0.59 5.08 0.61
127 INT249507 Regulation of Binding of Ephb1 1 0.38 0.58 0.55
128 INT278982 Regulation of EPHB2 6 0.44 1.97 0.53
129 INT273230 Negative_regulation of Cdk5r1 1 0.25 4.48 0.53
130 INT346830 Localization of Efnb2 1 0.69 0.47 0.53
131 INT134208 Negative_regulation of Ptk2 19 0.58 23.59 0.52
132 INT125139 Regulation of Gene_expression of EPHB2 3 0.44 1.07 0.52
133 INT274916 Negative_regulation of Localization of Ephb2 1 0.29 0 0.52
134 INT51236 Binding of Chn1 1 0.00 0 0.52
135 INT224498 Regulation of Positive_regulation of EPHB2 1 0.26 0.46 0.52
136 INT274915 Negative_regulation of Localization of Ephb6 1 0.38 0 0.51
137 INT126849 Positive_regulation of Binding of Ephb1 3 0.49 0.24 0.5
138 INT120403 Regulation of Phosphorylation of EPHB2 2 0.60 1.92 0.5
139 INT249517 Positive_regulation of Phosphorylation of Efnb2 1 0.03 0.31 0.5
140 INT333283 Positive_regulation of Gene_expression of Ephb1 3 0.32 1.17 0.47
141 INT117772 Binding of Ptk2 1 0.37 0.17 0.46
142 INT346833 Negative_regulation of Binding of Efnb2 1 0.42 0.6 0.45
143 INT201636 Protein_catabolism of Cdk5r1 3 0.18 2.79 0.44
144 INT274928 Negative_regulation of Binding of Ephb1 1 0.40 0 0.44
145 INT269613 Negative_regulation of Binding of EPHA3 2 0.11 0.27 0.43
146 INT119826 Positive_regulation of PTPN11 2 0.45 2.67 0.43
147 INT241304 Regulation of Transcription of PTPN11 3 0.43 4.49 0.41
148 INT326821 Positive_regulation of Protein_catabolism of Cdk5r1 1 0.13 1.9 0.41
149 INT235660 Gene_expression of EPHA2 27 0.75 23.46 0.4
150 INT271521 Phosphorylation of Ptk2 10 0.59 11.45 0.39
151 INT60976 Positive_regulation of Gene_expression of CHN1 1 0.14 3.91 0.39
152 INT16932 Localization of EPHA3 3 0.73 0.15 0.38
153 INT193542 Regulation of Regulation of Ephb1 2 0.25 0.79 0.38
154 INT181575 Phosphorylation of Crk 1 0.61 1.78 0.36
155 INT235655 Positive_regulation of Gene_expression of EPHA2 14 0.67 13.48 0.35
156 INT146933 Positive_regulation of Ephb6 8 0.05 3.22 0.35
157 INT60977 Localization of CHN1 2 0.57 1.9 0.35
158 INT274927 Negative_regulation of Ephb2 1 0.29 0 0.35
159 INT249513 Positive_regulation of Positive_regulation of Ephb2 1 0.33 0.15 0.34
160 INT249528 Phosphorylation of Ephb2 1 0.41 0.15 0.33
161 INT181580 Gene_expression of Crk 1 0.75 1.2 0.33
162 INT235658 Positive_regulation of EPHA2 4 0.67 3.42 0.32
163 INT145190 Positive_regulation of Efnb2 2 0.20 0.18 0.32
164 INT278976 Negative_regulation of Gene_expression of EPHB2 1 0.41 0.51 0.32
165 INT145185 Binding of Ephb2 2 0.28 0.31 0.31
166 INT247937 Localization of Cdk5r1 3 0.41 1.21 0.3
167 INT83594 Negative_regulation of Phosphorylation of Ptk2 5 0.42 1.62 0.29
168 INT249515 Regulation of Phosphorylation of Efnb2 1 0.01 0.2 0.29
169 INT179917 Negative_regulation of Negative_regulation of Ephb1 2 0.25 1.17 0.28
170 INT131265 Positive_regulation of Gene_expression of EPHB3 2 0.19 0 0.28
171 INT111164 Positive_regulation of Efna1 1 0.02 0.83 0.28
172 INT298974 Transcription of Cdk5r1 1 0.04 1.64 0.28
173 INT163893 Positive_regulation of Phosphorylation of EPHB1 1 0.49 0.43 0.27
174 INT163892 Phosphorylation of EPHB1 1 0.80 0.42 0.27
175 INT271522 Negative_regulation of Phosphorylation of Ptk2 3 0.19 2.09 0.26
176 INT273216 Negative_regulation of Gene_expression of Cdk5r1 1 0.25 1.73 0.25
177 INT109932 Protein_catabolism of EPHB2 3 0.86 0.14 0.24
178 INT109923 Positive_regulation of Protein_catabolism of EPHB2 1 0.49 0.14 0.24
179 INT119080 Negative_regulation of PTK2 15 0.56 8.88 0.23
180 INT22405 Positive_regulation of Crk 2 0.09 0.64 0.23
181 INT316046 Gene_expression of Ephb2 1 0.47 0.57 0.23
182 INT87338 Regulation of PTK2 10 0.62 4.75 0.21
183 INT308522 Positive_regulation of Positive_regulation of Ptk2 2 0.22 2.37 0.21
184 INT274731 Binding of EPHB1 3 0.22 0.76 0.2
185 INT241302 Transcription of PTPN11 3 0.67 2.81 0.2
186 INT352913 Regulation of EPHA2 1 0.05 0.74 0.2
187 INT326823 Positive_regulation of Localization of Cdk5r1 1 0.09 0.9 0.2
188 INT60978 Gene_expression of CHN1 2 0.24 2.1 0.19
189 INT292483 Negative_regulation of Positive_regulation of PTK2 2 0.41 3.51 0.18
190 INT134469 Positive_regulation of Binding of Cdk5r1 1 0.35 0.4 0.18
191 INT289228 Localization of Ptpn11 1 0.15 0.87 0.18
192 INT283561 Regulation of Gene_expression of Ptk2 5 0.42 1.1 0.17
193 INT260053 Transcription of Ephb6 2 0.04 0.62 0.17
194 INT181029 Transcription of Ephb1 2 0.51 0.51 0.17
195 INT183168 Regulation of Gene_expression of Epha1 2 0.03 0.08 0.16
196 INT23890 Binding of CDK5R1 2 0.36 0.23 0.16
197 INT183171 Positive_regulation of Gene_expression of Epha1 1 0.04 0.08 0.16
198 INT147730 Regulation of Positive_regulation of PTK2 1 0.35 0.33 0.15
199 INT83595 Negative_regulation of Gene_expression of Ptk2 1 0.23 1.62 0.14
200 INT131114 Positive_regulation of Gene_expression of Ptk2 1 0.49 0.27 0.14
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