GO:0048018

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Name receptor agonist activity
Categary Function
Go Slim No
Go Link GO:0048018
Unique Molecular Interactions 30
Total Molecular Interactions 35
Total Single Events 270
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for receptor agonist activity. They are ordered first by their pain relevance and then by number of times they were reported for receptor agonist activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT182200 Binding of CXCR5 and CXCL13 1 0.37 2.89 2.07
2 INT182207 Binding of CXCR2 and CXCL13 1 0.42 1.26 0.95
3 INT182210 Binding of CXCR4 and CXCL13 1 0.32 1.25 0.95
4 INT182189 Binding of CXCL1 and CXCL13 1 0.14 1.24 0.93
5 INT182209 Binding of CXCL12 and CXCL13 1 0.30 1.24 0.93
6 INT182196 Binding of IL8 and CXCL13 1 0.27 1.24 0.93
7 INT182204 Binding of CXCL5 and CXCL13 1 0.30 1.24 0.93
8 INT325807 CXCL13 Positive_regulation of CISH 1 0.16 3.65 0.89
9 INT236832 CSF2 Regulation of CXCL13 1 0.09 0.34 0.45
10 INT228055 WNT1 Positive_regulation of CTNND2 1 0.54 1.75 0.42
11 INT340609 Bdnf Regulation of Gene_expression of Wnt3a 1 0.53 0.31 0.36
12 INT236955 Binding of Cxcr5 and Cxcl13 1 0.28 2.26 0.34
13 INT257735 GAS6 Positive_regulation of Gene_expression of SAGE1 1 0.04 0.98 0.31
14 INT237082 Binding of Cxcl9 and Cxcl13 1 0.22 1.51 0.26
15 INT276301 Binding of CCL21 and CXCL13 1 0.04 1.85 0.18
16 INT340608 Binding of Creb1 and Wnt3a 1 0.30 0.24 0.14
17 INT287884 WNT5A Positive_regulation of THEMIS 1 0.00 0.08 0.13
18 INT287887 WNT1 Positive_regulation of Localization of BMP4 1 0.04 1.13 0.1
19 INT287879 Binding of WNT5A and FZD5 1 0.06 1.16 0.08
20 INT287877 WNT1 Positive_regulation of Localization of WISP1 1 0.03 0.56 0.05
21 INT287889 WNT1 Positive_regulation of KRT20 1 0.00 0.56 0.05
22 INT343744 mn Negative_regulation of Regulation of Wnt7a 1 0.01 0.1 0
23 INT251072 Wnt3a Positive_regulation of Axin2 1 0.23 0.29 0
24 INT326893 Binding of Tcf4 and Wnt3a 1 0.13 0 0
25 INT268521 Binding of WNT1 and MIR221 1 0.02 1.36 0
26 INT326896 Wnt3a Positive_regulation of Transcription of PLD2 1 0.24 0.06 0
27 INT251070 Wnt3a Positive_regulation of Cldn3 1 0.30 0.29 0
28 INT326894 Wnt3a Positive_regulation of Transcription of Pld1 1 0.24 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for receptor agonist activity. They are ordered first by their pain relevance and then by number of times they were reported in receptor agonist activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT182240 Gene_expression of CXCL13 25 0.59 22.77 11.96
2 INT340600 Gene_expression of Wnt3a 1 0.68 2.14 9.14
3 INT236839 Positive_regulation of CXCL13 14 0.44 19.27 5.81
4 INT181347 Gene_expression of Cxcl13 9 0.63 9.08 3.75
5 INT340603 Regulation of Gene_expression of Wnt3a 1 0.54 0.49 3.75
6 INT340595 Positive_regulation of Gene_expression of Wnt3a 1 0.61 0.86 3.11
7 INT236842 Positive_regulation of Gene_expression of CXCL13 6 0.32 3.91 2.55
8 INT182238 Binding of CXCL13 5 0.33 5.32 2.37
9 INT220178 Positive_regulation of Cxcl13 5 0.42 5.98 2.21
10 INT55090 Positive_regulation of Wnt7a 13 0.37 2.25 2.2
11 INT141833 Gene_expression of WNT1 14 0.75 10.57 2.1
12 INT264881 Localization of CXCL13 4 0.42 9.52 1.85
13 INT340596 Negative_regulation of Gene_expression of Wnt3a 1 0.51 0.38 1.4
14 INT141834 Negative_regulation of Gene_expression of WNT1 3 0.57 1.31 1.2
15 INT150074 Gene_expression of WNT5A 8 0.75 6.3 1.17
16 INT236945 Positive_regulation of Gene_expression of Cxcl13 3 0.38 3.98 1.11
17 INT257763 Positive_regulation of Gene_expression of GAS6 1 0.32 3.4 1.02
18 INT127647 Regulation of Wnt7a 3 0.07 1.28 1.01
19 INT340604 Regulation of Wnt3a 1 0.24 0 0.95
20 INT236947 Transcription of Cxcl13 2 0.43 1.74 0.84
21 INT236841 Negative_regulation of Gene_expression of CXCL13 3 0.27 2.17 0.83
22 INT141835 Negative_regulation of WNT1 2 0.41 1.02 0.83
23 INT182227 Transcription of CXCL13 2 0.60 2.07 0.81
24 INT257762 Positive_regulation of GAS6 1 0.32 2.7 0.81
25 INT257759 Gene_expression of GAS6 1 0.36 2.61 0.78
26 INT181338 Regulation of Cxcl13 1 0.10 0.52 0.69
27 INT28958 Negative_regulation of Wnt7a 3 0.45 0.49 0.65
28 INT325809 Positive_regulation of Positive_regulation of CXCL13 1 0.28 1.19 0.64
29 INT150075 Positive_regulation of Gene_expression of WNT5A 2 0.67 2.53 0.59
30 INT127648 Gene_expression of Wnt7a 2 0.13 1.11 0.56
31 INT236944 Positive_regulation of Transcription of Cxcl13 1 0.38 1.13 0.49
32 INT340598 Binding of Wnt3a 1 0.33 0.15 0.46
33 INT228057 Positive_regulation of WNT1 1 0.49 1.8 0.44
34 INT340606 Positive_regulation of Wnt3a 1 0.61 0.49 0.4
35 INT319417 Positive_regulation of Localization of CXCL13 1 0.23 3.84 0.36
36 INT216379 Positive_regulation of Gene_expression of WNT1 5 0.30 3.1 0.34
37 INT236843 Negative_regulation of CXCL13 1 0.27 0.24 0.29
38 INT51514 Positive_regulation of Wnt3a 3 0.04 3.32 0.28
39 INT319429 Positive_regulation of Transcription of CXCL13 1 0.23 1.19 0.26
40 INT325808 Regulation of Gene_expression of CXCL13 1 0.25 0.95 0.21
41 INT236954 Binding of Cxcl13 1 0.29 1.13 0.17
42 INT55089 Positive_regulation of Positive_regulation of Wnt7a 2 0.27 0.06 0.16
43 INT51512 Negative_regulation of Positive_regulation of Wnt3a 1 0.04 1.3 0.13
44 INT51513 Positive_regulation of Positive_regulation of Wnt3a 1 0.04 1.31 0.13
45 INT282594 Localization of WNT5A 2 0.18 0.89 0.1
46 INT214463 Binding of Wnt3a 2 0.26 0.23 0.08
47 INT290078 Regulation of WNT5A 1 0.07 2.3 0.07
48 INT159426 Positive_regulation of Gene_expression of Wnt7a 1 0.10 0.51 0.05
49 INT287956 Regulation of WNT1 2 0.26 2.38 0.04
50 INT287936 Regulation of Gene_expression of WNT1 1 0.20 1.06 0.04
51 INT214465 Localization of Wnt3a 2 0.52 0.29 0
52 INT251053 Gene_expression of Wnt3a 2 0.47 0.5 0
53 INT326853 Positive_regulation of Gene_expression of Wnt3a 1 0.36 0.2 0
54 INT266460 Positive_regulation of Binding of Wnt7a 1 0.04 0.06 0
55 INT251054 Regulation of Localization of Wnt3a 1 0.27 0.07 0
56 INT266459 Binding of Wnt7a 1 0.03 0.06 0
57 INT251066 Regulation of Gene_expression of Wnt3a 1 0.31 0.07 0
58 INT343743 Negative_regulation of Regulation of Wnt7a 1 0.04 0.1 0
59 INT326843 Negative_regulation of Gene_expression of Wnt3a 1 0.22 0.29 0
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