GO:0048069

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Name eye pigmentation
Categary Process
Go Slim No
Go Link GO:0048069
Unique Molecular Interactions 21
Total Molecular Interactions 25
Total Single Events 189
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for eye pigmentation. They are ordered first by their pain relevance and then by number of times they were reported for eye pigmentation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT278690 LEF1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83
2 INT278697 LEF1 Negative_regulation of STAT6 1 0.00 0.44 0.78
3 INT266108 Binding of COMT and HPS1 1 0.23 1.21 0.74
4 INT32662 Hps1 Negative_regulation of Localization of CGB 1 0.00 0 0.46
5 INT266101 Binding of HPS1 and SH2B2 1 0.17 0.67 0.16
6 INT266105 SH2B2 Positive_regulation of Gene_expression of HPS1 1 0.24 0.62 0.03
7 INT289101 Binding of KCNA1 and LEF1 1 0.00 2.58 0.03
8 INT337402 LEF1 Positive_regulation of E2F1 1 0.11 0 0
9 INT186958 Hps1 Positive_regulation of Tmed4 1 0.01 0.38 0
10 INT186955 Binding of Atp6v1e1 and Hps1 1 0.01 0.07 0
11 INT183648 Binding of Lef1 and Ctnnd2 1 0.07 1.05 0
12 INT337415 Negative_regulation of MIR203 Positive_regulation of Positive_regulation of LEF1 1 0.03 0.25 0
13 INT337405 MIR203 Regulation of LEF1 1 0.02 0.31 0
14 INT337411 Negative_regulation of MIR203 Positive_regulation of Gene_expression of LEF1 1 0.04 0.25 0
15 INT289102 KCNA1 Negative_regulation of Gene_expression of LEF1 1 0.00 0.44 0
16 INT289098 KCNA1 Regulation of LEF1 1 0.00 0.67 0
17 INT337417 MIR203 Negative_regulation of LEF1 1 0.04 0.57 0
18 INT220822 Binding of Myc and LEF1 1 0.26 0.08 0
19 INT220766 Binding of MAX and LEF1 1 0.40 0.08 0
20 INT186956 Binding of Des and Hps1 1 0.02 0.12 0
21 INT289100 KCNA1 Regulation of Gene_expression of LEF1 1 0.00 0.68 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for eye pigmentation. They are ordered first by their pain relevance and then by number of times they were reported in eye pigmentation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT148892 Binding of HPS1 13 0.37 19.21 3.35
2 INT47503 Gene_expression of HPS1 12 0.58 7.96 2.7
3 INT178291 Gene_expression of Hps1 26 0.67 8.2 2.52
4 INT266121 Transcription of HPS1 1 0.50 7.79 2.19
5 INT278715 Gene_expression of LEF1 10 0.33 5.43 1.54
6 INT278727 Negative_regulation of Gene_expression of LEF1 3 0.11 1.59 1.47
7 INT152951 Negative_regulation of LEF1 5 0.41 3.22 1.31
8 INT32660 Regulation of Hps1 8 0.16 2.3 1.21
9 INT24020 Positive_regulation of HPS1 6 0.44 6.14 1.08
10 INT24019 Negative_regulation of HPS1 7 0.37 7.94 1.04
11 INT167588 Localization of HPS1 3 0.65 1.24 0.9
12 INT278710 Phosphorylation of LEF1 1 0.05 0.76 0.82
13 INT178293 Positive_regulation of Gene_expression of Hps1 4 0.19 1.79 0.73
14 INT222005 Regulation of HPS1 2 0.33 3.3 0.6
15 INT178286 Positive_regulation of Hps1 9 0.61 3.86 0.5
16 INT86133 Binding of Hps1 7 0.48 1.7 0.33
17 INT111230 Transcription of LEF1 3 0.30 1.72 0.33
18 INT32661 Localization of Hps1 2 0.12 0 0.33
19 INT148891 Positive_regulation of Binding of HPS1 1 0.07 0.37 0.22
20 INT220802 Binding of LEF1 7 0.36 3.86 0.04
21 INT289116 Positive_regulation of Localization of LEF1 2 0.22 1.19 0.04
22 INT289110 Localization of LEF1 2 0.32 1.19 0.04
23 INT289127 Positive_regulation of LEF1 2 0.22 0.76 0
24 INT337456 Positive_regulation of Binding of LEF1 1 0.22 0 0
25 INT234916 Gene_expression of Lef1 1 0.04 0.25 0
26 INT289129 Positive_regulation of Gene_expression of LEF1 1 0.13 0.76 0
27 INT344889 Regulation of Gene_expression of Hps1 1 0.09 0 0
28 INT344886 Negative_regulation of Gene_expression of Hps1 1 0.06 0 0
29 INT344888 Transcription of Hps1 1 0.08 0 0
30 INT337461 Positive_regulation of Transcription of LEF1 1 0.22 0.26 0
31 INT289108 Negative_regulation of Transcription of LEF1 1 0.11 0.32 0
32 INT240607 Negative_regulation of Hps1 1 0.06 0.15 0
33 INT220775 Binding of Lef1 1 0.20 0.06 0
34 INT289124 Negative_regulation of Positive_regulation of LEF1 1 0.11 0.34 0
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