GO:0048102

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Name autophagic cell death
Categary Process
Go Slim No
Go Link GO:0048102
Unique Molecular Interactions 52
Total Molecular Interactions 63
Total Single Events 438
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for autophagic cell death. They are ordered first by their pain relevance and then by number of times they were reported for autophagic cell death. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT166398 CDKN1B Regulation of Gene_expression of CDKN1A 1 0.46 0.83 0.61
2 INT166399 CDKN1A Regulation of Gene_expression of CDKN1B 1 0.46 0.83 0.61
3 INT275388 Binding of Lamp1 and Cxcr4 1 0.01 1.45 0.52
4 INT275387 Binding of Lamp1 and Ccr5 1 0.01 1.45 0.52
5 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
6 INT28688 Binding of Kng1 and Ctsl1 1 0.15 0 0.31
7 INT166391 IFI27 Regulation of Gene_expression of CDKN1B 1 0.33 0.41 0.31
8 INT220521 Ugt1a6b Positive_regulation of Cdkn1b 1 0.01 2.38 0.31
9 INT166397 CDKN1B Regulation of Gene_expression of IFI27 1 0.33 0.41 0.31
10 INT237380 Binding of Cdkn2d and Il12b 1 0.01 0.45 0.26
11 INT307009 MT1JP Positive_regulation of Gene_expression of LAMP1 1 0.03 0.58 0.26
12 INT322543 Binding of FOXO3 and Cdkn1b 1 0.08 0.84 0.19
13 INT302146 CDKN2A Regulation of CDKN1B 1 0.11 0.51 0.14
14 INT233858 CHKA Positive_regulation of Gene_expression of CDKN1B 1 0.10 0.17 0.09
15 INT220514 Ppara Positive_regulation of Gene_expression of Cdkn1b 1 0.08 1 0.08
16 INT285025 Bnip3 Positive_regulation of Bak1 1 0.11 0.78 0.07
17 INT285032 Bnip3 Positive_regulation of Bax 1 0.28 0.77 0.07
18 INT302150 MRPL28 Regulation of CDKN1B 1 0.09 0.26 0.06
19 INT204074 Tp53 Positive_regulation of Cdkn1b 1 0.00 0.59 0.06
20 INT302136 LAMTOR1 Regulation of CDKN1B 1 0.08 0.26 0.06
21 INT257879 Negative_regulation of Eif4e Positive_regulation of Cdkn1b 1 0.28 0.54 0.06
22 INT204079 HP Positive_regulation of Gene_expression of Cdkn1b 1 0.00 0.6 0.05
23 INT302133 IFI27 Regulation of CDKN1B 1 0.11 0.26 0.05
24 INT302130 CDKN1A Regulation of CDKN1B 1 0.04 0.26 0.05
25 INT302141 CDKN1C Regulation of CDKN1B 1 0.09 0.26 0.05
26 INT220512 Cav1 Regulation of Positive_regulation of Cdkn1b 1 0.06 0.85 0.03
27 INT325154 CDKN1B Negative_regulation of CCNE2 1 0.07 0.1 0
28 INT295045 Akt1 Positive_regulation of Protein_catabolism of Cdkn1b 1 0.09 2.06 0
29 INT215707 Cdkn2a Negative_regulation of Cdkn1b 1 0.01 0 0
30 INT322546 Negative_regulation of PTPN6 Positive_regulation of Gene_expression of Cdkn1b 1 0.03 0.07 0
31 INT246217 Cdkn1b Positive_regulation of VEGFA 1 0.03 1.13 0
32 INT325156 CDKN1B Negative_regulation of CDK2 1 0.49 0.11 0
33 INT322536 Negative_regulation of Ctsb Positive_regulation of Gene_expression of Cdkn1b 1 0.02 0.3 0
34 INT322547 FOXO3 Regulation of Transcription of Cdkn1b 1 0.12 0.32 0
35 INT215697 Lamtor1 Negative_regulation of Cdkn1b 1 0.02 0 0
36 INT276379 Binding of SKP2 and Cdkn1b 1 0.02 0.57 0
37 INT271985 Tsc1 Regulation of Cdkn1b 1 0.04 0.1 0
38 INT322548 FOXO3 Regulation of Cdkn1b 1 0.09 0.23 0
39 INT215682 Binding of Cdkn1b and Cdk6 1 0.03 0 0
40 INT322545 PTPN6 Positive_regulation of Gene_expression of Cdkn1b 1 0.03 0.07 0
41 INT322540 Positive_regulation of Plaur Regulation of Gene_expression of Cdkn1b 1 0.06 0 0
42 INT322537 Ctsb Regulation of Gene_expression of Cdkn1b 1 0.01 0.1 0
43 INT354115 MIR222 Regulation of Gene_expression of CDKN1B 1 0.07 0.98 0
44 INT276336 Skp2 Regulation of Cdkn1b 1 0.00 0.57 0
45 INT322538 Plaur Regulation of Cdkn1b 1 0.14 0.19 0
46 INT276335 Binding of Cdkn1b and Skp2 1 0.00 0.57 0
47 INT215692 Stmn1 Negative_regulation of Cdkn1b 1 0.00 0 0
48 INT201756 CDKN1B Positive_regulation of Localization of Ccnd1 1 0.04 0 0
49 INT215694 Cdkn2b Negative_regulation of Cdkn1b 1 0.01 0 0
50 INT220519 Ugt1a6b Positive_regulation of Negative_regulation of Cdkn1b 1 0.01 0.24 0
51 INT322539 Ctsb Regulation of Cdkn1b 1 0.03 0.19 0
52 INT220523 Ugt1a6b Positive_regulation of Gene_expression of Cdkn1b 1 0.01 0.24 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for autophagic cell death. They are ordered first by their pain relevance and then by number of times they were reported in autophagic cell death. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT99549 Gene_expression of CDKN1B 30 0.75 17 5.15
2 INT99548 Positive_regulation of Gene_expression of CDKN1B 12 0.67 6.79 2.5
3 INT111038 Gene_expression of Cdkn1b 23 0.75 25.35 2.22
4 INT99547 Positive_regulation of CDKN1B 18 0.67 8.42 1.96
5 INT98782 Gene_expression of Cdkn1b 70 0.75 36.43 1.9
6 INT96746 Gene_expression of Lamp1 2 0.03 1.82 1.81
7 INT137505 Positive_regulation of Cdkn1b 18 0.67 10.55 1.54
8 INT160009 Transcription of CDKN1B 2 0.67 1.43 1.29
9 INT114220 Negative_regulation of Gene_expression of Cdkn1b 4 0.33 4.11 1.23
10 INT160008 Positive_regulation of Transcription of CDKN1B 1 0.49 0.98 1.1
11 INT111036 Positive_regulation of Cdkn1b 16 0.45 9 1.06
12 INT111037 Positive_regulation of Gene_expression of Cdkn1b 5 0.39 11.17 1.06
13 INT160012 Regulation of Gene_expression of CDKN1B 2 0.44 1.17 1.04
14 INT6534 Negative_regulation of Ctsl1 3 0.54 0.11 0.94
15 INT220498 Negative_regulation of Gene_expression of Cdkn1b 9 0.21 7.48 0.8
16 INT224579 Gene_expression of Cdkn2d 6 0.41 4.23 0.68
17 INT241621 Regulation of Cdkn1b 2 0.06 0.36 0.62
18 INT113850 Negative_regulation of Cdkn1b 4 0.42 3.45 0.6
19 INT28687 Gene_expression of Ctsl1 4 0.61 0.48 0.57
20 INT98786 Positive_regulation of Gene_expression of Cdkn1b 21 0.67 8.7 0.56
21 INT120358 Positive_regulation of Positive_regulation of CDKN1B 2 0.49 1.26 0.55
22 INT51843 Localization of Ctsl1 3 0.62 0.54 0.54
23 INT163828 Localization of Cdkn1b 4 0.66 5.2 0.48
24 INT137504 Positive_regulation of Positive_regulation of Cdkn1b 2 0.45 1.71 0.45
25 INT6533 Binding of Ctsl1 2 0.34 0 0.45
26 INT163829 Positive_regulation of Localization of Cdkn1b 2 0.17 0.96 0.45
27 INT348083 Positive_regulation of Ctsl1 1 0.08 0.21 0.4
28 INT99614 Gene_expression of LAMP1 7 0.75 4.57 0.39
29 INT204065 Regulation of Gene_expression of Cdkn1b 1 0.06 3.49 0.34
30 INT129153 Phosphorylation of CDKN1B 2 0.61 1.41 0.33
31 INT6536 Negative_regulation of Binding of Ctsl1 1 0.39 0 0.3
32 INT285014 Gene_expression of Bnip3 4 0.61 10.38 0.29
33 INT179043 Negative_regulation of Cdkn1b 7 0.36 5.99 0.22
34 INT36060 Protein_catabolism of Ctsl1 2 0.83 0.15 0.22
35 INT233869 Binding of CDKN1B 2 0.47 0.46 0.22
36 INT124178 Regulation of Ctsl1 1 0.23 0.19 0.22
37 INT179889 Negative_regulation of CDKN1B 4 0.57 1.71 0.21
38 INT306296 Regulation of CDKN1B 1 0.19 0.46 0.21
39 INT147190 Positive_regulation of Lamp1 1 0.35 0.34 0.19
40 INT179044 Regulation of Cdkn1b 4 0.22 2.64 0.18
41 INT201689 Protein_catabolism of CDKN1B 3 0.96 0.7 0.16
42 INT285018 Positive_regulation of Bnip3 1 0.34 1.67 0.15
43 INT257863 Positive_regulation of Protein_catabolism of Cdkn1b 1 0.45 0.43 0.14
44 INT257865 Negative_regulation of Protein_catabolism of Cdkn1b 1 0.42 0.43 0.14
45 INT257858 Protein_catabolism of Cdkn1b 1 0.64 0.43 0.14
46 INT348081 Positive_regulation of Gene_expression of Ctsl1 1 0.06 0.24 0.14
47 INT179034 Binding of Cdkn1b 7 0.31 5.12 0.12
48 INT36061 Negative_regulation of Protein_catabolism of Ctsl1 1 0.12 0.08 0.1
49 INT220494 Negative_regulation of Positive_regulation of Cdkn1b 1 0.14 0.35 0.1
50 INT233868 Localization of CDKN1B 2 0.73 0.37 0.09
51 INT147189 Positive_regulation of Positive_regulation of Lamp1 1 0.26 0.11 0.08
52 INT233871 Negative_regulation of Protein_catabolism of CDKN1B 1 0.57 0.27 0.08
53 INT200611 Positive_regulation of Gene_expression of LAMP1 2 0.49 0.74 0.07
54 INT285002 Negative_regulation of Gene_expression of Bnip3 1 0.37 0.75 0.07
55 INT285010 Positive_regulation of Positive_regulation of Bnip3 1 0.32 0.77 0.07
56 INT285020 Binding of Bnip3 1 0.22 0.71 0.07
57 INT179033 Negative_regulation of Regulation of Cdkn1b 1 0.36 1.34 0.05
58 INT180694 Regulation of Localization of Ctsl1 1 0.16 0 0.05
59 INT220489 Regulation of Gene_expression of Cdkn1b 1 0.20 1.57 0.04
60 INT307030 Localization of LAMP1 4 0.42 0.57 0.03
61 INT123524 Phosphorylation of Cdkn1b 4 0.29 2.29 0
62 INT200610 Regulation of Gene_expression of LAMP1 2 0.44 0.45 0
63 INT276307 Protein_catabolism of Cdkn1b 2 0.45 2.57 0
64 INT248390 Negative_regulation of Gene_expression of Cdkn2d 2 0.31 0.8 0
65 INT295040 Positive_regulation of Protein_catabolism of Cdkn1b 1 0.21 1 0
66 INT200612 Regulation of LAMP1 1 0.12 0.18 0
67 INT325178 Regulation of Positive_regulation of CDKN1B 1 0.44 0.05 0
68 INT325180 Negative_regulation of Gene_expression of CDKN1B 1 0.57 0.25 0
69 INT322505 Transcription of Cdkn1b 1 0.26 1.02 0
70 INT307025 Positive_regulation of Localization of LAMP1 1 0.12 0.1 0
71 INT322508 Regulation of Localization of Cdkn1b 1 0.10 0.4 0
72 INT204070 Negative_regulation of Positive_regulation of Cdkn1b 1 0.05 0.47 0
73 INT246216 Localization of Cdkn1b 1 0.42 0.22 0
74 INT200613 Negative_regulation of Gene_expression of LAMP1 1 0.41 0 0
75 INT322519 Negative_regulation of Transcription of Cdkn1b 1 0.16 0.07 0
76 INT322517 Positive_regulation of Transcription of Cdkn1b 1 0.17 0.64 0
77 INT246212 Positive_regulation of Positive_regulation of Cdkn1b 1 0.39 1.12 0
78 INT276316 Positive_regulation of Negative_regulation of Cdkn1b 1 0.07 0.56 0
79 INT248389 Negative_regulation of Cdkn2d 1 0.04 1.75 0
80 INT248391 Positive_regulation of Gene_expression of Cdkn2d 1 0.05 0.85 0
81 INT246215 Positive_regulation of Localization of Cdkn1b 1 0.28 0.22 0
82 INT322506 Negative_regulation of Phosphorylation of Cdkn1b 1 0.16 0.07 0
83 INT296001 Positive_regulation of Gene_expression of Bnip3 1 0.55 2.47 0
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