GO:0048143

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Name astrocyte activation
Categary Process
Go Slim No
Go Link GO:0048143
Unique Molecular Interactions 422
Total Molecular Interactions 584
Total Single Events 3985
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for astrocyte activation. They are ordered first by their pain relevance and then by number of times they were reported for astrocyte activation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52
2 INT87891 Agt Regulation of Cck 1 0.28 0 1.97
3 INT169468 Binding of Egfr and Spink3 1 0.37 3.73 1.83
4 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78
5 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
6 INT10202 Agt Positive_regulation of Avp 3 0.70 0 1.69
7 INT162482 Binding of Agt and Vta1 1 0.23 0 1.27
8 INT108409 AGT Positive_regulation of AGTR2 2 0.31 1.49 1.11
9 INT2457 Agt Positive_regulation of Localization of Avp 5 0.59 0.2 1.09
10 INT286798 Binding of Il6st and Cntf 1 0.10 1.34 0.97
11 INT161455 Mmp7 Positive_regulation of Egfr 1 0.03 0.19 0.92
12 INT12050 Agt Positive_regulation of Localization of Oxt 1 0.29 0 0.91
13 INT34457 AGT Positive_regulation of POMC 1 0.01 0 0.91
14 INT169469 Binding of Egfr and Tgfa 1 0.19 1.87 0.91
15 INT61587 Agt Negative_regulation of REN 1 0.00 0.42 0.91
16 INT69424 Binding of Agt and Oprd1 1 0.14 0 0.84
17 INT140280 Negative_regulation of Binding of Adora2a and Grina 1 0.21 0.64 0.82
18 INT140281 Binding of Adora2a and Grina 1 0.19 0.64 0.82
19 INT34458 AGT Negative_regulation of PENK 1 0.00 0 0.81
20 INT322397 Egfr Positive_regulation of Adarb1 1 0.00 0.08 0.8
21 INT47143 Negative_regulation of Agt Positive_regulation of Avp 1 0.22 0 0.79
22 INT72017 Binding of Adora2a and Ptprg 2 0.07 0 0.77
23 INT76498 Binding of Tacr1 and Adora2a 1 0.09 0 0.77
24 INT76499 Binding of Insr and Adora2a 1 0.08 0 0.76
25 INT82040 Adora2a Positive_regulation of Phosphorylation of Ppp1r1b 1 0.11 0 0.75
26 INT39095 Negative_regulation of Agt Positive_regulation of Localization of Ren 1 0.38 0 0.73
27 INT82041 Positive_regulation of Adora2a Positive_regulation of Phosphorylation of Ppp1r1b 1 0.12 0 0.72
28 INT391 Binding of Agt and Ace 2 0.33 1.5 0.68
29 INT141063 Agt Regulation of Agtr1a 1 0.28 1.18 0.68
30 INT194857 Positive_regulation of Adora2a Positive_regulation of Gene_expression of Vegfa 1 0.23 0.74 0.67
31 INT47145 Penk Negative_regulation of Agt 1 0.06 0 0.66
32 INT162878 Agt Regulation of Ang 1 0.21 1.15 0.66
33 INT239501 Binding of Adora2a and Mtx1 1 0.24 0.95 0.64
34 INT113780 AGT Positive_regulation of Positive_regulation of Nfkb1 1 0.00 1.25 0.64
35 INT57421 Oprd1 Regulation of Agt 1 0.29 0 0.62
36 INT56116 Agt Positive_regulation of Lhb 1 0.15 0 0.58
37 INT56117 Agt Positive_regulation of Positive_regulation of CGA 1 0.00 0 0.56
38 INT215644 Binding of Drd2 and Adora2a 1 0.03 0.23 0.55
39 INT73367 Agt Negative_regulation of Localization of Calca 1 0.43 0.26 0.54
40 INT34459 AGT Negative_regulation of MBTPS1 1 0.01 0 0.54
41 INT291386 Cntf Regulation of Gene_expression of Gria2 1 0.11 0.13 0.53
42 INT132438 Binding of AGT and OXTR 1 0.08 1.03 0.53
43 INT256019 Agt Negative_regulation of Lnpep 1 0.23 1.76 0.53
44 INT8438 Cntf Regulation of TAC1 1 0.20 0.18 0.52
45 INT8439 Cntf Regulation of VIP 1 0.20 0.18 0.52
46 INT8440 Cntf Regulation of LIF 1 0.33 0.18 0.52
47 INT56744 CNTF Positive_regulation of Cck 1 0.08 0.09 0.51
48 INT19296 AGT Positive_regulation of Localization of AVP 1 0.38 0 0.5
49 INT21315 AGT Positive_regulation of Npy 1 0.03 0.15 0.5
50 INT228448 PMAIP1 Negative_regulation of Cntf 1 0.00 0.07 0.49
51 INT56736 Cntf Positive_regulation of Chat 1 0.00 0.1 0.49
52 INT228447 Negative_regulation of PMAIP1 Negative_regulation of Cntf 1 0.00 0.07 0.49
53 INT56745 CNTF Positive_regulation of Chat 1 0.02 0.1 0.49
54 INT39078 Binding of Agt and Penk 1 0.24 0.42 0.48
55 INT47144 Negative_regulation of Creg2-ps1 Positive_regulation of Agt 1 0.01 0 0.48
56 INT47146 Creg2-ps1 Positive_regulation of Agt 1 0.01 0 0.48
57 INT39077 Agt Negative_regulation of Prss12 1 0.05 0.44 0.46
58 INT342633 ACE Regulation of Gene_expression of AGT 1 0.01 0.14 0.46
59 INT291384 Cntf Positive_regulation of Slc1a3 1 0.26 0.34 0.45
60 INT291387 Cntf Positive_regulation of Slc1a2 1 0.12 0.34 0.45
61 INT151958 Negative_regulation of Agt Positive_regulation of Agtrap 1 0.39 0 0.44
62 INT151959 Agt Positive_regulation of Agtrap 1 0.63 0 0.44
63 INT114341 Agt Positive_regulation of AGT 3 0.01 1.15 0.43
64 INT184543 Agt Positive_regulation of Ccl2 1 0.16 3.18 0.43
65 INT345288 AGT Positive_regulation of Localization of CCL2 1 0.01 1.5 0.43
66 INT36459 Binding of Agt and Positive_regulation of Localization of Avp 1 0.38 0.19 0.43
67 INT345291 AGT Positive_regulation of CCL2 1 0.01 1.39 0.43
68 INT291393 Cntf Regulation of GTS 1 0.05 0 0.42
69 INT89666 Binding of Adora2a and Drd2 1 0.54 0.4 0.42
70 INT242992 Binding of Agt and Ppara 1 0.20 1.44 0.42
71 INT36460 Binding of Agt and Avp 1 0.28 0.16 0.4
72 INT302871 Negative_regulation of Adora2a Positive_regulation of Phosphorylation of Th 1 0.26 0.12 0.4
73 INT275156 Agt Positive_regulation of Rac1 1 0.03 2.89 0.4
74 INT64384 Agt Negative_regulation of Son 1 0.26 0 0.39
75 INT185530 Binding of AGT and EDNRA 1 0.00 0.31 0.38
76 INT91720 Binding of BDNF and CNTF 1 0.09 1.71 0.38
77 INT39092 Agt Negative_regulation of Ren 1 0.39 0 0.37
78 INT53257 CALCRL Negative_regulation of Binding of Agt 1 0.00 0 0.36
79 INT44112 Agt Regulation of Penk 1 0.08 0 0.35
80 INT239503 Binding of Adora2a and Aes 1 0.24 0.85 0.35
81 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34
82 INT4638 Binding of Agt and Adarb1 3 0.01 0 0.34
83 INT352231 VEGFA Negative_regulation of Cntf 1 0.04 0.22 0.34
84 INT330122 Agt Positive_regulation of Gene_expression of Agtr1a 1 0.03 0.69 0.34
85 INT352230 VEGFA Negative_regulation of Gene_expression of Cntf 1 0.04 0.22 0.34
86 INT115162 Adora2a Regulation of Gene_expression of Jun 1 0.49 0.36 0.34
87 INT330119 Agt Positive_regulation of Gene_expression of Bdkrb1 1 0.37 0.63 0.34
88 INT324525 PGE Positive_regulation of Positive_regulation of Egfr 1 0.41 1.05 0.33
89 INT162157 Binding of SGCG and Agt 1 0.33 0.35 0.33
90 INT324522 PGE Positive_regulation of Phosphorylation of Egfr 1 0.56 1.04 0.33
91 INT324524 PGE Positive_regulation of Egfr 1 0.38 1.05 0.33
92 INT147436 Agt Positive_regulation of Gene_expression of Ros1 1 0.02 0.5 0.33
93 INT115161 Adora2a Regulation of Gene_expression of Cpe 1 0.04 0.36 0.33
94 INT242995 Agt Positive_regulation of Spp1 1 0.36 1.82 0.33
95 INT229363 Negative_regulation of Binding of Agt and Agtr1a 2 0.22 0.9 0.32
96 INT44127 Agt Negative_regulation of DSPP 1 0.02 0 0.32
97 INT56115 Agt Regulation of Lhb 1 0.16 0 0.32
98 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31
99 INT254122 Adora2a Regulation of Aliq1 1 0.01 0.85 0.3
100 INT200631 AGT Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
101 INT288911 AGT Positive_regulation of CYBB 3 0.07 2.96 0.28
102 INT291383 Fig4 Regulation of Gene_expression of Cntf 1 0.10 0 0.28
103 INT116853 Chdh Regulation of Positive_regulation of Agt 1 0.11 0.19 0.28
104 INT63988 Cntf Regulation of Positive_regulation of Sds 1 0.22 0 0.28
105 INT45541 Agt Positive_regulation of Lnpep 1 0.03 0 0.27
106 INT45545 Agt Positive_regulation of Oxt 1 0.23 0 0.27
107 INT126550 Agt Positive_regulation of Gene_expression of Nsfl1c 1 0.39 1.07 0.26
108 INT234980 Positive_regulation of Egfr Positive_regulation of Adam17 1 0.09 1.33 0.26
109 INT242991 Agt Positive_regulation of Gene_expression of Spp1 1 0.21 0.66 0.26
110 INT9528 Agt Positive_regulation of Localization of Pomc 2 0.50 0.14 0.25
111 INT342456 AGT Positive_regulation of Gene_expression of CCL2 1 0.07 0.63 0.25
112 INT126547 Agt Positive_regulation of Nfkb1 1 0.46 0.99 0.25
113 INT88555 Adora2a Negative_regulation of Vegfc 1 0.00 0.17 0.25
114 INT126548 Negative_regulation of Agt Positive_regulation of Nfkb1 1 0.29 0.99 0.25
115 INT297258 Binding of Agt and Agtr2 1 0.23 0.7 0.25
116 INT126553 Agt Positive_regulation of Nfkb1 1 0.06 0.99 0.25
117 INT256028 Binding of Agt and Lnpep 1 0.19 1.16 0.24
118 INT41588 Binding of AGT and Lhb 1 0.00 0 0.24
119 INT41589 Binding of AGT and Prl 1 0.00 0 0.24
120 INT126551 Agt Positive_regulation of Gene_expression of Ptgs1 1 0.25 0.92 0.24
121 INT126552 Agt Positive_regulation of Gene_expression of Ptgs2 1 0.32 0.92 0.24
122 INT191492 Binding of AGT and NLRP3 1 0.01 0.35 0.23
123 INT126549 Agt Positive_regulation of Ptgs2 1 0.32 0.9 0.23
124 INT289998 CNTF Negative_regulation of Casp3 1 0.04 0.99 0.22
125 INT289981 Cntf Negative_regulation of Casp3 1 0.02 1.01 0.22
126 INT224130 Positive_regulation of Adora2a Positive_regulation of ADCY1 1 0.01 0.11 0.22
127 INT224087 Adrbk1 Negative_regulation of Adora2a 1 0.10 0.13 0.22
128 INT289999 Binding of CNTF and Casp3 1 0.04 0.99 0.22
129 INT72015 Binding of Adora2a and Gnai2 1 0.01 0 0.21
130 INT222566 Agt Positive_regulation of Localization of Prl 1 0.08 0.23 0.21
131 INT229360 Agt Positive_regulation of Agtr1a 2 0.48 1.26 0.2
132 INT275159 Agt Positive_regulation of Phosphorylation of Stat3 1 0.04 1.44 0.2
133 INT274094 EDN1 Positive_regulation of AGT 1 0.16 0.95 0.2
134 INT249993 Binding of Agt and Igkv4-55 1 0.02 0.49 0.2
135 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19
136 INT184540 Agt Regulation of Gene_expression of Ccl2 1 0.08 1.66 0.18
137 INT41978 Binding of Agt and Htr1a 1 0.41 0.54 0.18
138 INT229223 Binding of AGT and FAS 1 0.08 0.91 0.17
139 INT36568 AGT Positive_regulation of FBF1 1 0.39 0.5 0.17
140 INT224094 Adrbk1 Regulation of Negative_regulation of Adora2a 1 0.06 0 0.17
141 INT233904 NLRP3 Positive_regulation of AGT 1 0.06 0.81 0.17
142 INT229224 Positive_regulation of Binding of AGT and FAS 1 0.09 0.92 0.17
143 INT36567 Negative_regulation of AGT Positive_regulation of FBF1 1 0.36 0.5 0.17
144 INT111863 Negative_regulation of Binding of AGT and LNPEP 1 0.09 0 0.16
145 INT112132 Gast Positive_regulation of Positive_regulation of Egfr 1 0.33 0.13 0.16
146 INT111861 Binding of AGT and LNPEP 1 0.07 0 0.16
147 INT21509 Agt Regulation of Edn1 1 0.53 0 0.15
148 INT72817 Agt Negative_regulation of Avp 1 0.07 0.34 0.14
149 INT347071 Negative_regulation of REN Negative_regulation of Positive_regulation of AGT 1 0.35 0.44 0.14
150 INT34430 AGT Positive_regulation of Localization of POMC 1 0.30 0.31 0.14
151 INT170817 CMA1 Positive_regulation of Gene_expression of AGT 1 0.19 1.41 0.14
152 INT224129 Binding of DRD2 and Adora2a 1 0.03 0.19 0.14
153 INT344946 AGT Regulation of Negative_regulation of ACE 1 0.21 0.61 0.14
154 INT293115 Agt Regulation of Positive_regulation of Crh 1 0.16 0.37 0.14
155 INT293117 Agt Regulation of Gene_expression of Aqp2 1 0.23 0.36 0.14
156 INT293123 Agtr1a Regulation of Negative_regulation of Agt 1 0.14 0.25 0.14
157 INT178446 Binding of Egfr and ras 1 0.04 0.13 0.13
158 INT178431 Positive_regulation of Binding of Egfr and ras 1 0.05 0.13 0.13
159 INT254855 Agt Positive_regulation of Tgfb1 1 0.03 0.18 0.13
160 INT33749 Crh Positive_regulation of Localization of Agt 1 0.31 0 0.13
161 INT59808 Binding of AGT and PLCB1 1 0.02 0 0.13
162 INT59809 AGT Positive_regulation of PLCB1 1 0.03 0 0.13
163 INT59810 ADRA1D Positive_regulation of AGT 1 0.01 0 0.13
164 INT351974 Agt Positive_regulation of Gene_expression of Stk11 1 0.51 11.1 0.12
165 INT107226 Agt Positive_regulation of AFF1 1 0.01 0 0.12
166 INT44974 Agt Positive_regulation of Gene_expression of Ptger2 1 0.02 0.42 0.12
167 INT33750 Apoa2 Regulation of Agt 1 0.07 0 0.12
168 INT182496 AGT Positive_regulation of Phosphorylation of STAT3 1 0.03 0.79 0.12
169 INT345290 AGT Positive_regulation of NOX1 1 0.00 1.11 0.12
170 INT229359 Agt Positive_regulation of Binding of Agtr1a 1 0.25 0.9 0.12
171 INT171390 Src Positive_regulation of Phosphorylation of Egfr 1 0.13 0 0.11
172 INT119157 Agt Positive_regulation of Positive_regulation of Agtr2 1 0.06 0 0.11
173 INT171385 Ppp1cc Positive_regulation of Phosphorylation of Egfr 1 0.15 0 0.11
174 INT352497 AGT Positive_regulation of Binding of CRS 1 0.14 0.87 0.11
175 INT222503 Agt Positive_regulation of Localization of Gh1 1 0.02 0.23 0.11
176 INT300306 Agt Positive_regulation of Mapk14 1 0.14 1.51 0.11
177 INT256023 Lnpep Regulation of Gene_expression of Agt 1 0.18 0.14 0.1
178 INT46502 Agt Positive_regulation of Odc1 1 0.18 0 0.1
179 INT334893 ACE Negative_regulation of Gene_expression of AGT 1 0.03 1.41 0.1
180 INT356272 Egf Negative_regulation of Gene_expression of Egfr 1 0.15 0.2 0.1
181 INT148102 AGT Positive_regulation of Gene_expression of STK24 1 0.37 0.96 0.1
182 INT10906 Agt Regulation of Localization of Nppb 1 0.10 0.19 0.1
183 INT171164 Agt Regulation of Positive_regulation of Rorb 1 0.02 0.64 0.1
184 INT256029 Lnpep Regulation of Agt 1 0.18 0.14 0.1
185 INT349860 Binding of Cntf and Lifr 1 0.39 0.22 0.1
186 INT258018 Binding of AGT and RASGRP1 1 0.00 1.59 0.1
187 INT257870 Agt Positive_regulation of Akt1 2 0.18 1.5 0.09
188 INT231273 Binding of Egfr and Nrg1 1 0.12 0 0.09
189 INT256018 Agt Positive_regulation of Oxt 1 0.12 0.31 0.09
190 INT254641 CGA Positive_regulation of AGT 1 0.17 1.51 0.08
191 INT355021 Cntf Positive_regulation of SOAT1 1 0.02 0.7 0.08
192 INT354753 Ren Regulation of Agt 1 0.14 0.98 0.08
193 INT355022 Cntf Positive_regulation of JAK1 1 0.00 0.69 0.08
194 INT267969 Binding of AGT and TRPV1 1 0.00 0.44 0.08
195 INT355009 Cntf Positive_regulation of Il6st 1 0.02 0.69 0.08
196 INT267970 Negative_regulation of Binding of AGT and TRPV1 1 0.00 0.44 0.08
197 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
198 INT300304 Positive_regulation of Mapk14 Positive_regulation of Agt 1 0.14 1.5 0.08
199 INT254639 CGA Positive_regulation of Gene_expression of AGT 1 0.18 1.51 0.08
200 INT171165 Agt Positive_regulation of Positive_regulation of Nfkb1 1 0.23 1.09 0.08

Single Events

The table below shows the top 100 pain related interactions that have been reported for astrocyte activation. They are ordered first by their pain relevance and then by number of times they were reported in astrocyte activation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT385 Gene_expression of Agt 182 0.78 63.62 37.91
2 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08
3 INT1159 Negative_regulation of Agt 133 0.59 40.14 31.67
4 INT1158 Regulation of Agt 106 0.61 29.4 30.29
5 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73
6 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91
7 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92
8 INT2066 Localization of Agt 56 0.80 9.95 16.25
9 INT15042 Gene_expression of Adora2a 37 0.77 3.77 14.24
10 INT108063 Gene_expression of Adora2a 29 0.78 13.11 13.78
11 INT3962 Regulation of AGT 50 0.62 20.96 13.01
12 INT50227 Positive_regulation of Adora2a 32 0.50 5.17 12.75
13 INT4199 Binding of Agt 76 0.48 21.06 12.66
14 INT398 Localization of AGT 45 0.78 16.97 11.54
15 INT72784 Positive_regulation of Adora2a 26 0.70 16.52 11.47
16 INT8065 Binding of AGT 54 0.48 20.54 10.85
17 INT386 Positive_regulation of Gene_expression of Agt 37 0.70 15.92 8.73
18 INT8423 Gene_expression of Cntf 29 0.69 11.69 8.4
19 INT23209 Binding of Adora2a 17 0.38 2.04 8.35
20 INT54755 Negative_regulation of Adora2a 17 0.58 2.7 7.75
21 INT113705 Gene_expression of Egfr 228 0.78 149.05 7.59
22 INT16359 Positive_regulation of Gene_expression of AGT 30 0.49 28.27 6.14
23 INT5762 Negative_regulation of Gene_expression of Agt 18 0.57 6.09 5.84
24 INT112124 Positive_regulation of Egfr 71 0.70 47.82 5.61
25 INT83014 Binding of Adora2a 13 0.48 5.57 5.33
26 INT89664 Negative_regulation of Adora2a 11 0.59 7.81 5.07
27 INT51468 Regulation of Adora2a 8 0.48 1.5 4.84
28 INT3332 Protein_catabolism of AGT 23 0.87 3.17 4.39
29 INT103914 Phosphorylation of Egfr 35 0.82 16.98 4.31
30 INT50228 Positive_regulation of Positive_regulation of Adora2a 8 0.39 0.1 4
31 INT120715 Positive_regulation of Egfr 15 0.68 5.53 3.77
32 INT119506 Negative_regulation of Egfr 32 0.55 23.75 3.67
33 INT101701 Regulation of Adora2a 8 0.45 2.3 3.63
34 INT81458 Positive_regulation of Cntf 11 0.47 4.18 3.18
35 INT124954 Gene_expression of Egfr 26 0.75 15.08 3.12
36 INT120562 Negative_regulation of Egfr 108 0.59 79.38 3.11
37 INT17857 Negative_regulation of Gene_expression of AGT 25 0.46 21.16 2.45
38 INT148071 Gene_expression of Agt 42 0.74 44.9 2.43
39 INT4270 Negative_regulation of Negative_regulation of Agt 10 0.43 1.08 2.43
40 INT254118 Negative_regulation of Gene_expression of Adora2a 3 0.42 2.54 2.43
41 INT183167 Positive_regulation of Gene_expression of Adora2a 4 0.70 2.37 2.31
42 INT27988 Negative_regulation of Positive_regulation of AGT 11 0.42 5.71 2.27
43 INT10201 Positive_regulation of Localization of Agt 8 0.50 0.97 2.21
44 INT103917 Positive_regulation of Phosphorylation of Egfr 12 0.68 7.23 2.18
45 INT228442 Localization of Cntf 8 0.63 4.2 2.12
46 INT286801 Positive_regulation of Gene_expression of Cntf 4 0.62 3.01 2.12
47 INT12005 Negative_regulation of Localization of Agt 6 0.57 1.49 2.06
48 INT57939 Negative_regulation of Gene_expression of Adora2a 4 0.36 0.15 2.02
49 INT79915 Positive_regulation of Agt 27 0.56 12.97 1.96
50 INT12801 Negative_regulation of Regulation of Agt 4 0.43 1.2 1.96
51 INT72785 Positive_regulation of Positive_regulation of Adora2a 2 0.10 1.34 1.96
52 INT43944 Negative_regulation of Positive_regulation of Agt 4 0.42 1.44 1.93
53 INT288630 Gene_expression of Cntf 6 0.75 3.99 1.89
54 INT194847 Negative_regulation of Positive_regulation of Adora2a 3 0.32 4.52 1.88
55 INT112131 Positive_regulation of Positive_regulation of Egfr 10 0.49 9.95 1.85
56 INT120563 Positive_regulation of Gene_expression of Egfr 56 0.70 46.19 1.82
57 INT15980 Positive_regulation of Positive_regulation of Agt 6 0.50 2.99 1.76
58 INT124953 Negative_regulation of Gene_expression of Egfr 6 0.42 1.97 1.75
59 INT8422 Binding of Cntf 8 0.37 4.54 1.72
60 INT3152 Transcription of Agt 7 0.72 5.09 1.68
61 INT68582 Localization of CNTF 4 0.73 2.02 1.68
62 INT8421 Regulation of Cntf 6 0.44 1.46 1.67
63 INT76496 Localization of Adora2a 3 0.48 0.3 1.54
64 INT34768 Negative_regulation of Negative_regulation of AGT 10 0.25 2.79 1.42
65 INT8067 Negative_regulation of Binding of AGT 12 0.25 10.33 1.39
66 INT239215 Binding of Agt 9 0.38 6.75 1.35
67 INT11306 Regulation of Gene_expression of Agt 7 0.45 3.29 1.31
68 INT11241 Transcription of AGT 4 0.52 1.83 1.27
69 INT19319 Negative_regulation of Binding of Agt 9 0.42 3.42 1.24
70 INT79916 Negative_regulation of Agt 14 0.47 6 1.22
71 INT47644 Positive_regulation of Localization of AGT 4 0.45 1.24 1.2
72 INT91595 Regulation of Gene_expression of Adora2a 1 0.52 0 1.19
73 INT28594 Positive_regulation of Transcription of Agt 2 0.47 1.3 1.15
74 INT115621 Positive_regulation of Binding of AGT 1 0.02 0 1.15
75 INT164400 Positive_regulation of CNTF 3 0.49 1.66 0.96
76 INT52090 Transcription of Adora2a 3 0.41 0.33 0.96
77 INT72006 Positive_regulation of Negative_regulation of Adora2a 2 0.40 0.26 0.94
78 INT144415 Regulation of Positive_regulation of Egfr 2 0.27 0.42 0.86
79 INT352587 Transcription of CNTF 1 0.30 5.18 0.84
80 INT230806 Positive_regulation of Gene_expression of Agt 11 0.55 16.08 0.83
81 INT144416 Regulation of Egfr 5 0.57 4.97 0.83
82 INT171361 Regulation of Egfr 16 0.62 8.36 0.81
83 INT144414 Positive_regulation of Positive_regulation of Egfr 1 0.49 0.65 0.8
84 INT286804 Negative_regulation of Gene_expression of Cntf 2 0.38 0.71 0.79
85 INT131286 Binding of Egfr 26 0.44 13.58 0.78
86 INT120603 Negative_regulation of Cntf 6 0.35 3.57 0.78
87 INT302869 Phosphorylation of Adora2a 1 0.49 0.25 0.78
88 INT302868 Positive_regulation of Phosphorylation of Adora2a 1 0.41 0.25 0.78
89 INT80147 Negative_regulation of Binding of Adora2a 2 0.43 0.15 0.77
90 INT21943 Positive_regulation of Positive_regulation of AGT 6 0.46 3.29 0.75
91 INT34715 Regulation of Regulation of AGT 2 0.37 0.96 0.75
92 INT89663 Localization of Adora2a 1 0.74 0.74 0.75
93 INT194852 Protein_catabolism of Adora2a 1 0.56 0.6 0.75
94 INT148074 Regulation of Agt 9 0.49 5.42 0.7
95 INT38735 Protein_catabolism of Agt 7 0.99 2.79 0.7
96 INT160461 Phosphorylation of Agt 1 0.31 0.4 0.7
97 INT160463 Positive_regulation of Phosphorylation of Agt 1 0.19 0.41 0.7
98 INT224109 Phosphorylation of Adora2a 1 0.52 0.07 0.69
99 INT34769 Regulation of Gene_expression of AGT 3 0.19 1.39 0.67
100 INT70418 Negative_regulation of CNTF 1 0.58 0.62 0.63
101 INT215637 Regulation of Regulation of Adora2a 1 0.14 0.16 0.61
102 INT141458 Regulation of Gene_expression of Adora2a 2 0.45 0.67 0.57
103 INT320644 Binding of Egfr 7 0.34 5.9 0.56
104 INT215639 Positive_regulation of Binding of Adora2a 1 0.24 0.24 0.55
105 INT40021 Regulation of Binding of Agt 4 0.59 1.53 0.53
106 INT32618 Regulation of Positive_regulation of Agt 2 0.43 0.42 0.52
107 INT286805 Positive_regulation of Localization of Cntf 1 0.40 1.3 0.52
108 INT224106 Regulation of Negative_regulation of Adora2a 1 0.17 0.26 0.51
109 INT47645 Negative_regulation of Localization of AGT 2 0.11 1.09 0.49
110 INT228441 Negative_regulation of Localization of Cntf 1 0.19 0.07 0.49
111 INT224107 Negative_regulation of Negative_regulation of Adora2a 1 0.28 0.32 0.48
112 INT103916 Negative_regulation of Phosphorylation of Egfr 12 0.59 7.03 0.47
113 INT142943 Phosphorylation of Egfr 5 0.81 1.56 0.45
114 INT142942 Positive_regulation of Phosphorylation of Egfr 4 0.68 1.52 0.45
115 INT99588 Positive_regulation of Binding of Agt 2 0.69 0.23 0.45
116 INT72143 Regulation of Binding of Adora2a 1 0.17 0 0.45
117 INT14039 Regulation of Regulation of Agt 1 0.30 0 0.44
118 INT169355 Localization of Egfr 6 0.75 3.24 0.43
119 INT33017 Negative_regulation of Protein_catabolism of AGT 3 0.37 0 0.42
120 INT102385 Regulation of Transcription of Adora2a 1 0.21 0.09 0.4
121 INT102387 Negative_regulation of Transcription of Adora2a 1 0.09 0.24 0.37
122 INT185350 Negative_regulation of Gene_expression of Egfr 24 0.59 13.21 0.35
123 INT95605 Regulation of Binding of AGT 3 0.44 0.2 0.34
124 INT27928 Phosphorylation of AGT 1 0.52 0.15 0.34
125 INT81457 Positive_regulation of Regulation of Cntf 1 0.47 0.09 0.34
126 INT27929 Negative_regulation of Phosphorylation of AGT 1 0.27 0.15 0.34
127 INT164399 Gene_expression of CNTF 5 0.65 1.73 0.33
128 INT4636 Positive_regulation of Regulation of Agt 4 0.50 1.3 0.3
129 INT43398 Regulation of Localization of Agt 1 0.28 0 0.3
130 INT221765 Positive_regulation of Gene_expression of Adora2a 2 0.49 0.2 0.27
131 INT3331 Positive_regulation of Protein_catabolism of AGT 1 0.33 0 0.27
132 INT224108 Positive_regulation of Localization of Adora2a 1 0.32 0.14 0.27
133 INT224114 Regulation of Localization of Adora2a 1 0.29 0.14 0.27
134 INT164617 Protein_catabolism of Agt 2 0.79 5.3 0.25
135 INT239213 Localization of Agt 6 0.64 3.26 0.22
136 INT289992 Phosphorylation of Cntf 1 0.30 1 0.22
137 INT224117 Negative_regulation of Positive_regulation of Adora2a 1 0.27 0.11 0.22
138 INT224105 Regulation of Phosphorylation of Adora2a 1 0.17 0 0.21
139 INT289982 Phosphorylation of CNTF 1 0.79 0.99 0.21
140 INT230802 Positive_regulation of Positive_regulation of Agt 2 0.40 0.41 0.2
141 INT1770 Positive_regulation of Negative_regulation of Agt 2 0.49 1.09 0.17
142 INT256015 Negative_regulation of Regulation of Agt 1 0.18 0.16 0.17
143 INT79914 Positive_regulation of Negative_regulation of Agt 1 0.50 0.19 0.17
144 INT185352 Regulation of Gene_expression of Egfr 5 0.62 2.33 0.16
145 INT171378 Negative_regulation of Binding of Egfr 3 0.43 1.48 0.16
146 INT224115 Positive_regulation of Phosphorylation of Adora2a 1 0.32 0 0.16
147 INT171365 Negative_regulation of Regulation of Egfr 1 0.33 0.06 0.16
148 INT224103 Negative_regulation of Phosphorylation of Adora2a 1 0.27 0 0.16
149 INT289348 Positive_regulation of Positive_regulation of Cntf 1 0.20 0.19 0.15
150 INT144682 Negative_regulation of Regulation of Egfr 1 0.43 0.41 0.15
151 INT299514 Localization of Egfr 2 0.37 0.38 0.14
152 INT256004 Negative_regulation of Gene_expression of Agt 2 0.34 8.07 0.13
153 INT239214 Positive_regulation of Localization of Agt 2 0.55 1.89 0.13
154 INT119156 Positive_regulation of Protein_catabolism of Agt 1 0.49 0 0.13
155 INT214619 Positive_regulation of Negative_regulation of AGT 1 0.04 0.98 0.13
156 INT233419 Negative_regulation of Positive_regulation of Egfr 2 0.40 0.97 0.12
157 INT256008 Regulation of Gene_expression of Agt 4 0.36 5.03 0.11
158 INT219647 Negative_regulation of Negative_regulation of Egfr 1 0.19 0.13 0.1
159 INT50849 Negative_regulation of Regulation of AGT 2 0.42 1.26 0.08
160 INT88135 Negative_regulation of Transcription of Agt 1 0.34 0.16 0.08
161 INT226648 Negative_regulation of Positive_regulation of Egfr 1 0.10 0 0.08
162 INT288915 Regulation of Positive_regulation of AGT 1 0.41 0.82 0.08
163 INT211211 Positive_regulation of Negative_regulation of Egfr 1 0.50 1.36 0.08
164 INT144614 Binding of CNTF 2 0.36 1.44 0.07
165 INT241728 Regulation of Transcription of Adora2a 1 0.42 0.27 0.07
166 INT349815 Regulation of Cntf 1 0.26 0.21 0.07
167 INT241725 Transcription of Adora2a 1 0.67 0.27 0.07
168 INT299512 Regulation of Localization of Egfr 1 0.13 0.11 0.06
169 INT205021 Positive_regulation of Gene_expression of Egfr 3 0.64 4.15 0.05
170 INT279191 Regulation of Negative_regulation of Egfr 2 0.45 1.44 0.05
171 INT185349 Transcription of Egfr 8 0.72 4.01 0.04
172 INT354748 Negative_regulation of Protein_catabolism of Agt 1 0.43 0.58 0.04
173 INT230800 Positive_regulation of Regulation of Agt 1 0.40 1.1 0.04
174 INT185347 Negative_regulation of Transcription of Egfr 1 0.59 1.1 0.04
175 INT351640 Positive_regulation of Protein_catabolism of Agt 1 0.40 0.85 0.03
176 INT333025 Negative_regulation of Positive_regulation of Agt 3 0.34 0.74 0
177 INT226657 Negative_regulation of Negative_regulation of Egfr 2 0.43 1.39 0
178 INT27724 Regulation of Negative_regulation of Agt 2 0.35 0.32 0
179 INT241004 Transcription of Agt 2 0.42 7.14 0
180 INT231270 Positive_regulation of Localization of Egfr 1 0.15 0 0
181 INT226635 Negative_regulation of Protein_catabolism of Egfr 1 0.10 0.48 0
182 INT333008 Regulation of Localization of Agt 1 0.10 0 0
183 INT226703 Protein_catabolism of Egfr 1 0.22 0.61 0
184 INT226650 Positive_regulation of Protein_catabolism of Egfr 1 0.16 0.47 0
185 INT164401 Regulation of Gene_expression of CNTF 1 0.52 0.47 0
186 INT307800 Negative_regulation of Transcription of Agt 1 0.25 4.61 0
187 INT279188 Regulation of Localization of Egfr 1 0.45 0.76 0
188 INT230797 Regulation of Negative_regulation of Agt 1 0.36 0.68 0
189 INT164398 Regulation of CNTF 1 0.26 0.77 0
190 INT279189 Regulation of Positive_regulation of Egfr 1 0.45 0.96 0
191 INT301988 Positive_regulation of Binding of Egfr 1 0.18 0.42 0
192 INT120602 Positive_regulation of Negative_regulation of Cntf 1 0.27 0 0
193 INT351641 Negative_regulation of Protein_catabolism of Agt 1 0.34 0.8 0
194 INT333023 Negative_regulation of Localization of Agt 1 0.09 0 0
195 INT351642 Negative_regulation of Binding of Agt 1 0.34 0.88 0
196 INT144616 Positive_regulation of Binding of CNTF 1 0.49 0.53 0
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