GO:0048156

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Name tau protein binding
Categary Function
Go Slim No
Go Link GO:0048156
Unique Molecular Interactions 175
Total Molecular Interactions 232
Total Single Events 2912
Pain Genes Associated 16

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for tau protein binding. They are ordered first by their pain relevance and then by number of times they were reported for tau protein binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT275850 Binding of NDUFAB1 and SNCA 1 0.00 3.78 3.16
2 INT130839 Gfap Positive_regulation of S100B 1 0.51 1.9 1.56
3 INT228681 Fkbp4 Negative_regulation of Trib3 1 0.00 0.57 1.2
4 INT297332 Apoe Negative_regulation of Gene_expression of Mpz 1 0.02 1.09 0.87
5 INT274785 S100B Positive_regulation of Ngf 1 0.05 0.61 0.8
6 INT208354 Binding of Apoe and Hdl1 12 0.13 8.37 0.77
7 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
8 INT152947 Dlg4 Regulation of Sgk1 1 0.09 0.18 0.76
9 INT152949 Homer1 Regulation of Sgk1 1 0.28 0.18 0.76
10 INT152867 HTR1A Negative_regulation of Localization of S100b 1 0.46 0 0.75
11 INT274786 Ngf Positive_regulation of Gene_expression of S100B 1 0.05 0.63 0.71
12 INT297344 Apoe Regulation of Binding of Alms1 1 0.08 1.1 0.61
13 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
14 INT261372 Gsk3b Regulation of Gene_expression of Ifi205 1 0.00 0.24 0.58
15 INT297331 Apoe Negative_regulation of Gene_expression of Il6 1 0.14 0.61 0.57
16 INT290594 BDNF Positive_regulation of Localization of S100B 1 0.08 0.6 0.57
17 INT254761 Igh-Dex Positive_regulation of Apoe 1 0.00 0.08 0.52
18 INT116862 Apoe Positive_regulation of Il10 1 0.30 0.69 0.5
19 INT116863 Apoe Negative_regulation of Hand1 1 0.37 0.69 0.5
20 INT254768 DNMT1 Positive_regulation of Gene_expression of Apoe 1 0.02 0.05 0.49
21 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
22 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46
23 INT191686 Igh-Dex Positive_regulation of Sgk1 1 0.04 1.79 0.46
24 INT319554 Sgk1 Regulation of Cdkn1a 1 0.26 0.09 0.45
25 INT142608 Apoe Regulation of Gene_expression of Il6 1 0.25 1.01 0.44
26 INT254760 Igh-Dex Positive_regulation of Gene_expression of Apoe 1 0.00 0 0.42
27 INT329085 Csf2 Positive_regulation of Apoe 1 0.00 1.23 0.42
28 INT326303 Binding of CRP and FKBP4 1 0.15 1.22 0.41
29 INT288545 Gsk3b Negative_regulation of gr 1 0.25 0.38 0.38
30 INT129769 Binding of LYZ and S100B 1 0.33 0.86 0.37
31 INT152453 Gsk3b Regulation of Nfkb1 1 0.02 1.68 0.36
32 INT66369 Pomc Regulation of Positive_regulation of Gsk3b 1 0.07 0 0.35
33 INT321366 Gsk3b Regulation of Gene_expression of CYP8B1 1 0.01 0.21 0.33
34 INT342810 Binding of Adarb1 and Gsk3b 1 0.00 0.36 0.3
35 INT328407 Nlrp1a Negative_regulation of Gene_expression of Snca 1 0.07 0.31 0.29
36 INT328410 Nlrp1a Negative_regulation of Snca 1 0.07 0.31 0.29
37 INT254759 Igh-Dex Positive_regulation of Localization of Apoe 1 0.00 0.32 0.28
38 INT254769 Binding of LDLR and Apoe 1 0.03 0 0.28
39 INT325530 Positive_regulation of Gsk3b Negative_regulation of Gene_expression of Wnt2 1 0.03 0.63 0.28
40 INT312894 Binding of Gsk3b and Positive_regulation of Gene_expression of Hdac6 1 0.08 1.3 0.27
41 INT297338 Apoe Regulation of Gnb5 1 0.06 1.12 0.27
42 INT254772 DNMT1 Positive_regulation of Apoe 1 0.02 0 0.25
43 INT78293 Binding of Apoe and Ldlr 1 0.20 0.25 0.24
44 INT78295 Binding of Ptpra and Apoe 1 0.42 0.25 0.24
45 INT297334 Gnb5 Regulation of Apoe 1 0.09 0.83 0.24
46 INT78294 Negative_regulation of Binding of Ptpra and Apoe 1 0.48 0.25 0.24
47 INT254773 PPARA Positive_regulation of Gene_expression of Apoe 1 0.01 0.07 0.24
48 INT78292 Negative_regulation of Binding of Apoe and Ldlr 1 0.23 0.25 0.24
49 INT254774 DNMT1 Positive_regulation of Localization of Apoe 1 0.01 0.31 0.23
50 INT270433 PLAT Positive_regulation of Positive_regulation of Gsk3b 1 0.04 0.5 0.21
51 INT134494 Binding of APOE and Alb 1 0.11 0.45 0.2
52 INT261401 Binding of Gsk3b and ADHD1 1 0.00 1.62 0.18
53 INT317322 Snca Regulation of Positive_regulation of Th 1 0.01 0.23 0.17
54 INT208360 Binding of Abca1 and Apoe 1 0.15 0.74 0.17
55 INT197499 Binding of Apoe and Tfrc 1 0.14 1.54 0.17
56 INT122528 Apoe Regulation of Eno2 1 0.05 0.29 0.16
57 INT122529 Apoe Regulation of S100B 1 0.18 0.29 0.16
58 INT297345 Apoe Negative_regulation of Csf2 1 0.17 0.66 0.16
59 INT297333 Apoe Negative_regulation of Positive_regulation of Tlr4 1 0.10 1.02 0.14
60 INT297343 Binding of Apoe and Tlr4 1 0.09 0.94 0.14
61 INT96590 Mog Regulation of S100B 1 0.32 0.97 0.13
62 INT297339 Tlr4 Negative_regulation of Gene_expression of Apoe 1 0.10 0.73 0.13
63 INT261381 Nsdhl Regulation of Gene_expression of S100b 1 0.06 0.82 0.13
64 INT330800 Binding of S100A1 and S100B 1 0.32 0.5 0.13
65 INT312893 Gsk3b Positive_regulation of Hdac6 1 0.07 0.65 0.13
66 INT263320 Gsk3b Regulation of Uts2r 1 0.02 0.68 0.13
67 INT263318 Akt1 Regulation of Gsk3b 1 0.02 0.75 0.13
68 INT96589 Mbp Regulation of S100B 1 0.34 0.97 0.13
69 INT354327 Gsk3b Positive_regulation of Gene_expression of Ide 1 0.17 0.33 0.13
70 INT268634 Ptpn2 Positive_regulation of Positive_regulation of Gsk3b 1 0.02 1.08 0.11
71 INT289768 Akt1 Regulation of Phosphorylation of Gsk3b 1 0.04 0.45 0.11
72 INT158141 Binding of HOXD13 and SNCA 1 0.54 0.41 0.11
73 INT268626 Mpz Positive_regulation of Positive_regulation of Gsk3b 1 0.29 1.08 0.11
74 INT208361 Positive_regulation of Binding of Apoe and Hdl1 1 0.12 1.22 0.1
75 INT32546 Gsk3b Negative_regulation of Localization of Gnrh1 1 0.05 0 0.1
76 INT32547 Gsk3b Negative_regulation of Localization of LH 1 0.04 0 0.1
77 INT328413 Binding of Snca and Nlrp1a 1 0.06 0.75 0.1
78 INT297346 Apoe Negative_regulation of Localization of TNF 1 0.48 0.26 0.1
79 INT137395 Binding of CD99 and S100B 1 0.17 1.04 0.09
80 INT83270 Snca Regulation of Napepld 1 0.14 0 0.09
81 INT205135 Binding of APOE and APP 1 0.05 0.35 0.08
82 INT268627 Ptpn2 Positive_regulation of Gsk3b 1 0.02 1.7 0.08
83 INT316112 Binding of S100B and SAE1 1 0.05 1.5 0.08
84 INT300641 Binding of APOE and CRP 1 0.41 0.81 0.07
85 INT297330 Apoe Positive_regulation of Gene_expression of Nos2 1 0.26 0.34 0.07
86 INT268630 Mpz Positive_regulation of Regulation of Gsk3b 1 0.18 0.57 0.07
87 INT354328 Gsk3b Regulation of Gs 1 0.16 0.84 0.07
88 INT354329 Gsk3b Regulation of Gene_expression of Gs 1 0.16 0.84 0.07
89 INT308665 Binding of Apoe and Gopc 1 0.02 0.49 0.07
90 INT308663 Apoe Regulation of Car2 1 0.02 0.44 0.07
91 INT50078 Binding of APOE and NPPA 1 0.30 0.42 0.07
92 INT326067 APOA1 Positive_regulation of Localization of APOE 1 0.61 4.22 0.07
93 INT221235 Akt1 Negative_regulation of Gsk3b 1 0.06 0.14 0.06
94 INT193966 AKT1 Negative_regulation of Gsk3b 1 0.05 0.75 0.05
95 INT193969 AKT1 Negative_regulation of Phosphorylation of Gsk3b 1 0.05 0.75 0.05
96 INT181814 Gsk3b Regulation of Gata4 1 0.06 0.37 0.05
97 INT251468 Binding of APOE and DBT 1 0.03 1.18 0.05
98 INT193964 Mapk1 Negative_regulation of Gsk3b 1 0.00 0.74 0.05
99 INT208356 Hdl1 Positive_regulation of Apoe 1 0.12 1.25 0.04
100 INT316109 TEAD1 Regulation of S100B 1 0.00 1.16 0.04
101 INT235551 Gene_expression of Hras1 Negative_regulation of Positive_regulation of Apoe 1 0.03 0.57 0.04
102 INT208357 Hdl1 Positive_regulation of Localization of Apoe 1 0.12 1.26 0.04
103 INT208350 Positive_regulation of Hdl1 Positive_regulation of Apoe 1 0.12 1.27 0.04
104 INT290181 Binding of APOE and PLTP 1 0.17 1.61 0.04
105 INT290810 Gsk3b Regulation of Arntl 1 0.15 0 0.04
106 INT204247 S100B Regulation of CD68 1 0.03 1.05 0.04
107 INT303092 Gsk3b Positive_regulation of NEUROG2 1 0.01 0.16 0.03
108 INT194483 Binding of Apoe and Chol1 1 0.24 0.51 0.03
109 INT290808 Gsk3b Positive_regulation of Arntl 1 0.25 0.17 0.03
110 INT234981 Binding of Dsg3 and Negative_regulation of Gsk3b 1 0.07 0.3 0.03
111 INT244656 Binding of S100B and SLC4A1 1 0.14 1.72 0.03
112 INT303083 Rorb Regulation of Gsk3b 1 0.00 0.52 0.03
113 INT208352 Apoe Regulation of Localization of Em 1 0.04 1.15 0.03
114 INT194481 Binding of Apoe and Apob 1 0.07 0.51 0.03
115 INT308658 Binding of Apoa2 and Apoe 1 0.17 0.15 0.03
116 INT268629 Mpz Regulation of Phosphorylation of Gsk3b 1 0.26 1.05 0.03
117 INT303079 Gsk3b Positive_regulation of Cebpg 1 0.08 0.16 0.03
118 INT265906 IGF1 Regulation of Gsk3b 1 0.25 1.31 0.03
119 INT337811 Gene_expression of Gsk3b Positive_regulation of Phosphorylation of Akt1 1 0.37 0.37 0.03
120 INT341487 Binding of APOE and TLR2 1 0.00 0.3 0
121 INT290811 Binding of Mgst1 and Gsk3b 1 0.05 0 0
122 INT290807 Positive_regulation of Akt1 Positive_regulation of Phosphorylation of Gsk3b 1 0.14 0 0
123 INT326065 APOE Positive_regulation of LCAT 1 0.53 0.84 0
124 INT209987 Binding of APOE and LDLR 1 0.24 0 0
125 INT317313 Atp13a2 Negative_regulation of Snca 1 0.13 0.59 0
126 INT268628 Mpz Positive_regulation of Phosphorylation of Gsk3b 1 0.25 0.43 0
127 INT180294 Positive_regulation of Binding of CPB1 and S100B 1 0.09 0 0
128 INT208349 Regulation of Binding of Apoc3 and Apoe 1 0.01 0.38 0
129 INT249185 Binding of S100B and Positive_regulation of CYBB 1 0.11 0 0
130 INT249195 Binding of CA2 and S100B 1 0.07 0 0
131 INT268635 Mpz Positive_regulation of Gsk3b 1 0.17 0.43 0
132 INT90283 Binding of APOE and Il1a 1 0.01 0 0
133 INT290809 Binding of Arntl and Gsk3b 1 0.20 0 0
134 INT180672 Sgk1 Regulation of Ecm1 1 0.03 0 0
135 INT201080 Binding of APOE and HLA-C 1 0.41 0.31 0
136 INT180295 Binding of CPB1 and S100B 1 0.08 0 0
137 INT353802 Binding of APOE and Apob 1 0.05 0.83 0
138 INT208355 Binding of Apoc3 and Apoe 1 0.01 0.76 0
139 INT180302 Positive_regulation of Binding of S100B and Tg(EGFR)0Jlj 1 0.05 0 0
140 INT249180 Binding of NCF2 and S100B 1 0.05 0 0
141 INT198933 Binding of Apoe and App 1 0.33 0.19 0
142 INT180303 Binding of S100B and Tg(EGFR)0Jlj 1 0.03 0 0
143 INT317315 Gene_expression of Snca Negative_regulation of Psmb10 1 0.00 0.52 0
144 INT317320 Binding of Snca and Atp13a2 1 0.08 0.58 0
145 INT353801 Binding of APOE and Cd320 1 0.22 0.83 0
146 INT235486 S100B Positive_regulation of Binding of CA2 1 0.13 0.08 0
147 INT235077 Akt1 Positive_regulation of Phosphorylation of Gsk3b 1 0.07 0.53 0
148 INT283718 Binding of Id2 and Aatf 1 0.03 0.19 0
149 INT250152 Binding of APOE and UBE4B 1 0.21 1.2 0
150 INT326059 APOA1 Positive_regulation of Gene_expression of APOE 1 0.61 0.38 0
151 INT249155 Binding of CYBA and S100B 1 0.06 0 0
152 INT281610 Positive_regulation of Akt1 Positive_regulation of Gsk3b 1 0.02 0.12 0
153 INT353804 Binding of APOE and Ldlr 1 0.16 0.84 0
154 INT326057 APOA1 Regulation of Localization of APOE 1 0.54 1.36 0
155 INT249174 Binding of AKT1 and S100B 1 0.02 0 0
156 INT230713 Binding of Prkcd and Gsk3b 1 0.34 0 0
157 INT201082 Binding of APOE and HLA-B 1 0.54 1.54 0
158 INT268632 Mpz Regulation of Gsk3b 1 0.22 0 0
159 INT249194 S100B Positive_regulation of CYBA 1 0.06 0 0
160 INT290806 Gene_expression of Akt1 Positive_regulation of Phosphorylation of Gsk3b 1 0.14 0 0
161 INT284093 VWF Negative_regulation of APOE 1 0.40 2.32 0
162 INT303004 Adm Positive_regulation of Gsk3b 1 0.04 0.97 0
163 INT263319 Binding of Gsk3b and Uts2r 1 0.01 0 0
164 INT312769 Binding of Apoe and Pon1 1 0.04 0.86 0
165 INT353803 Binding of APOE and Hdl1 1 0.01 0.83 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for tau protein binding. They are ordered first by their pain relevance and then by number of times they were reported in tau protein binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26
2 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4
3 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51
4 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35
5 INT123593 Gene_expression of Snca 58 0.78 35.76 12.87
6 INT127123 Positive_regulation of Snca 35 0.70 14.76 10.1
7 INT135372 Positive_regulation of Gsk3b 72 0.70 50.03 9.28
8 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17
9 INT197493 Localization of Apoe 61 0.79 27.48 7.06
10 INT142264 Positive_regulation of Apoe 47 0.50 26.35 6.94
11 INT117299 Localization of S100b 19 0.78 1.58 6.8
12 INT182351 Positive_regulation of Gene_expression of Apoe 38 0.50 19.78 6.72
13 INT23465 Gene_expression of S100b 31 0.76 15.09 6.2
14 INT63042 Binding of Apoe 59 0.48 31.23 5.88
15 INT124370 Positive_regulation of Gene_expression of Gsk3b 47 0.67 24.56 5.4
16 INT135374 Binding of Gsk3b 46 0.48 24.36 4.75
17 INT55758 Positive_regulation of Apoe 15 0.70 11.71 4.69
18 INT17742 Localization of S100B 44 0.80 17.14 4.65
19 INT123594 Negative_regulation of Snca 19 0.59 4.43 4.59
20 INT127122 Positive_regulation of Gene_expression of Snca 11 0.69 15.36 4.56
21 INT168151 Gene_expression of Sgk1 10 0.76 5.58 4.35
22 INT66366 Positive_regulation of Gsk3b 15 0.68 6.56 4.27
23 INT167284 Phosphorylation of Gsk3b 88 0.82 36.03 4.21
24 INT116642 Negative_regulation of Gsk3b 13 0.57 7.16 3.83
25 INT15033 Gene_expression of Apoe 18 0.78 14.97 3.75
26 INT104624 Negative_regulation of Apoe 26 0.59 19.25 3.71
27 INT135373 Regulation of Gsk3b 35 0.62 18.11 3.53
28 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52
29 INT191667 Positive_regulation of Sgk1 6 0.68 4.59 3.45
30 INT119412 Gene_expression of Snca 15 0.66 11.27 3.39
31 INT110245 Gene_expression of SNCA 11 0.77 8.29 3.36
32 INT72141 Binding of Apoe 11 0.37 10.91 3.27
33 INT97710 Localization of Apoe 1 0.79 7.18 3.2
34 INT82168 Positive_regulation of S100b 20 0.68 9.72 3.08
35 INT66367 Gene_expression of Gsk3b 16 0.45 9.75 3.07
36 INT123595 Regulation of Snca 7 0.62 4.3 3.06
37 INT131929 Positive_regulation of Gene_expression of S100B 25 0.67 12.61 2.83
38 INT50080 Binding of APOE 38 0.45 29.61 2.67
39 INT23775 Regulation of S100B 24 0.62 16.75 2.57
40 INT152865 Positive_regulation of Localization of S100b 3 0.68 0 2.53
41 INT97713 Negative_regulation of Apoe 4 0.59 4.57 2.52
42 INT228675 Binding of Fkbp4 1 0.01 1.14 2.28
43 INT208344 Positive_regulation of Localization of Apoe 22 0.48 9.6 2.27
44 INT142265 Regulation of Apoe 20 0.60 9.52 2.23
45 INT84060 Regulation of Apoe 4 0.62 3.33 2.05
46 INT233660 Transcription of Sgk1 3 0.70 0.51 2.03
47 INT127124 Regulation of Gene_expression of Snca 2 0.62 0.17 2.03
48 INT127125 Localization of Snca 6 0.81 8.24 1.88
49 INT204018 Localization of Gsk3b 27 0.71 13.67 1.87
50 INT58563 Negative_regulation of S100B 13 0.51 11.75 1.77
51 INT148266 Positive_regulation of SNCA 5 0.67 3.17 1.74
52 INT152864 Regulation of Localization of S100b 2 0.52 0 1.66
53 INT96814 Negative_regulation of APOE 13 0.59 10.64 1.61
54 INT125767 Positive_regulation of Gene_expression of S100b 6 0.49 4.08 1.52
55 INT201271 Phosphorylation of Snca 3 0.82 4.22 1.45
56 INT180712 Gene_expression of Sgk1 2 0.47 1.52 1.41
57 INT217388 Negative_regulation of Gene_expression of Apoe 11 0.59 6.07 1.4
58 INT124247 Negative_regulation of Gene_expression of Snca 12 0.59 3.87 1.39
59 INT97716 Transcription of Apoe 3 0.53 2.61 1.36
60 INT51064 Regulation of Gene_expression of S100B 13 0.60 5.02 1.34
61 INT125766 Regulation of S100b 7 0.38 4.31 1.33
62 INT233665 Positive_regulation of Transcription of Sgk1 2 0.49 0.3 1.29
63 INT97715 Regulation of Gene_expression of Apoe 3 0.62 1.98 1.23
64 INT113336 Positive_regulation of Gene_expression of Apoe 3 0.70 1.79 1.23
65 INT110244 Positive_regulation of Gene_expression of SNCA 5 0.69 4.66 1.19
66 INT167283 Negative_regulation of Phosphorylation of Gsk3b 12 0.59 7.94 1.16
67 INT134036 Regulation of Gsk3b 4 0.60 1.42 1.15
68 INT139236 Regulation of Sgk1 2 0.37 0.84 1.14
69 INT32545 Localization of Gsk3b 9 0.07 2.88 1.11
70 INT151753 Transcription of Snca 6 0.69 1.99 1.11
71 INT208536 Positive_regulation of Positive_regulation of Gsk3b 6 0.30 4.83 1.11
72 INT233633 Negative_regulation of Positive_regulation of Sgk1 1 0.37 0.11 1.08
73 INT161706 Negative_regulation of Gene_expression of S100B 8 0.43 2.69 1.06
74 INT292945 Positive_regulation of Positive_regulation of Snca 4 0.69 2.42 1.05
75 INT217390 Negative_regulation of Positive_regulation of Apoe 3 0.37 1.95 1.05
76 INT286344 Positive_regulation of Gene_expression of Snca 1 0.41 2.84 1.03
77 INT233644 Negative_regulation of Sgk1 1 0.38 0.11 1.02
78 INT24809 Positive_regulation of Fkbp4 3 0.40 1.57 1
79 INT116646 Regulation of Negative_regulation of Gsk3b 2 0.44 0.39 0.99
80 INT51066 Binding of S100B 24 0.48 13.5 0.97
81 INT97714 Negative_regulation of Localization of Apoe 1 0.58 1.83 0.97
82 INT151752 Positive_regulation of Transcription of Snca 2 0.50 0.99 0.92
83 INT144543 Localization of Sgk1 1 0.71 0.96 0.91
84 INT124246 Binding of Snca 10 0.37 6.53 0.9
85 INT261360 Binding of Gsk3b 5 0.36 2.85 0.9
86 INT117444 Regulation of Sgk1 4 0.60 1.35 0.87
87 INT167285 Positive_regulation of Phosphorylation of Gsk3b 17 0.50 5.92 0.82
88 INT156945 Positive_regulation of Negative_regulation of Gsk3b 6 0.38 4.58 0.82
89 INT66365 Positive_regulation of Gene_expression of Gsk3b 2 0.07 0.95 0.81
90 INT142597 Regulation of Binding of Apoe 1 0.34 2.21 0.8
91 INT180300 Positive_regulation of Positive_regulation of S100B 3 0.50 2.07 0.79
92 INT128447 Positive_regulation of Localization of S100B 2 0.67 0.9 0.79
93 INT116644 Phosphorylation of Gsk3b 4 0.61 0.68 0.78
94 INT233632 Regulation of Transcription of Sgk1 1 0.39 0.22 0.78
95 INT204002 Negative_regulation of Gene_expression of Gsk3b 15 0.55 8.57 0.77
96 INT152863 Negative_regulation of Localization of S100b 1 0.42 0 0.75
97 INT147008 Negative_regulation of Gene_expression of S100b 2 0.27 0.55 0.74
98 INT197495 Negative_regulation of Localization of Apoe 6 0.43 2.19 0.73
99 INT44612 Positive_regulation of APOE 16 0.67 5.73 0.72
100 INT247255 Positive_regulation of Gene_expression of Sgk1 1 0.30 0.84 0.72
101 INT270428 Negative_regulation of Binding of APOE 2 0.41 1.16 0.7
102 INT113335 Regulation of Transcription of Apoe 1 0.27 0.51 0.7
103 INT242137 Negative_regulation of Positive_regulation of Gsk3b 7 0.39 2.99 0.67
104 INT175580 Localization of APOE 10 0.76 18.84 0.65
105 INT312882 Negative_regulation of Hdac6 1 0.52 1.86 0.63
106 INT97708 Regulation of Localization of Apoe 1 0.61 2.06 0.62
107 INT204006 Negative_regulation of Localization of Gsk3b 6 0.40 1.66 0.6
108 INT144545 Positive_regulation of Sgk1 1 0.44 0.62 0.59
109 INT230679 Positive_regulation of Binding of Gsk3b 3 0.42 1.42 0.58
110 INT113334 Positive_regulation of Positive_regulation of Apoe 1 0.50 0.6 0.56
111 INT208537 Regulation of Gene_expression of Gsk3b 4 0.36 2.15 0.52
112 INT197322 Protein_catabolism of Apoe 6 0.71 3.52 0.51
113 INT217370 Phosphorylation of Apoe 2 0.63 1.8 0.49
114 INT279363 Binding of FKBP4 1 0.05 0.22 0.49
115 INT191670 Positive_regulation of Gene_expression of Sgk1 1 0.33 2.42 0.46
116 INT96816 Regulation of APOE 8 0.45 6.62 0.44
117 INT319552 Regulation of Gene_expression of Sgk1 1 0.60 0 0.44
118 INT288540 Negative_regulation of Binding of Gsk3b 4 0.53 2.12 0.43
119 INT208552 Negative_regulation of Negative_regulation of Gsk3b 3 0.31 1.8 0.43
120 INT235064 Regulation of Positive_regulation of Gsk3b 3 0.41 1.5 0.42
121 INT148264 Transcription of SNCA 1 0.40 0.25 0.42
122 INT125765 Negative_regulation of Positive_regulation of S100b 2 0.42 0.06 0.4
123 INT97712 Negative_regulation of Transcription of Apoe 1 0.43 1.05 0.4
124 INT204012 Regulation of Negative_regulation of Gsk3b 4 0.42 4.51 0.39
125 INT343972 Negative_regulation of Binding of SNCA 1 0.36 0.2 0.39
126 INT208538 Regulation of Phosphorylation of Gsk3b 3 0.49 4.49 0.38
127 INT169628 Binding of SNCA 4 0.47 3.53 0.36
128 INT66364 Regulation of Positive_regulation of Gsk3b 1 0.07 0 0.35
129 INT156723 Regulation of Localization of S100B 2 0.44 2.61 0.34
130 INT131542 Negative_regulation of Gene_expression of APOE 6 0.40 3.92 0.33
131 INT343973 Localization of SNCA 1 0.63 0.07 0.3
132 INT311128 Positive_regulation of Regulation of Apoe 1 0.30 0.3 0.3
133 INT175687 Transcription of Apoe 4 0.72 2.12 0.29
134 INT96815 Regulation of Gene_expression of APOE 2 0.62 1.1 0.29
135 INT312879 Regulation of Hdac6 1 0.55 0.76 0.29
136 INT268620 Regulation of Localization of Gsk3b 3 0.35 2.12 0.28
137 INT161705 Positive_regulation of Negative_regulation of S100B 1 0.50 0.56 0.28
138 INT97711 Positive_regulation of Transcription of Apoe 1 0.46 1.06 0.27
139 INT254756 Regulation of Positive_regulation of Apoe 1 0.20 0.22 0.26
140 INT312887 Gene_expression of Hdac6 1 0.60 1.28 0.25
141 INT345254 Positive_regulation of Localization of Gsk3b 2 0.01 0.91 0.24
142 INT312883 Regulation of Regulation of Hdac6 1 0.40 0.38 0.24
143 INT204021 Transcription of Gsk3b 8 0.57 2.75 0.23
144 INT165392 Positive_regulation of Regulation of S100B 2 0.50 0.56 0.23
145 INT142052 Binding of Snca 4 0.47 1.02 0.22
146 INT268621 Positive_regulation of Localization of Gsk3b 4 0.40 1.54 0.22
147 INT116647 Positive_regulation of Phosphorylation of Gsk3b 1 0.37 0.18 0.22
148 INT323964 Negative_regulation of Binding of Apoe 1 0.39 0.35 0.22
149 INT198892 Regulation of Binding of Apoe 6 0.45 2.94 0.21
150 INT292944 Regulation of Positive_regulation of Snca 1 0.45 0.36 0.21
151 INT93077 Negative_regulation of Localization of S100B 3 0.57 0.58 0.2
152 INT193810 Phosphorylation of APOE 2 0.27 1.13 0.2
153 INT257418 Negative_regulation of Transcription of Snca 1 0.43 0.93 0.19
154 INT51065 Transcription of S100B 3 0.60 0.83 0.17
155 INT166361 Phosphorylation of SNCA 1 0.70 0.72 0.17
156 INT254754 Regulation of Localization of Apoe 1 0.20 0.39 0.17
157 INT319544 Localization of Sgk1 1 0.73 0.34 0.16
158 INT157084 Localization of Snca 1 0.51 0.17 0.16
159 INT254755 Positive_regulation of Transcription of Apoe 1 0.16 0.41 0.16
160 INT343974 Negative_regulation of Gene_expression of SNCA 1 0.31 0.09 0.16
161 INT319289 Protein_catabolism of Snca 1 0.35 0.93 0.15
162 INT312881 Positive_regulation of Hdac6 1 0.45 0.67 0.15
163 INT286343 Negative_regulation of Gene_expression of Snca 1 0.26 0.65 0.15
164 INT96772 Positive_regulation of Gene_expression of APOE 5 0.66 5.44 0.14
165 INT198894 Regulation of Gene_expression of Apoe 2 0.44 0.56 0.14
166 INT104623 Regulation of Negative_regulation of Apoe 2 0.45 0.73 0.12
167 INT268617 Negative_regulation of Regulation of Gsk3b 3 0.28 1.84 0.11
168 INT326081 Negative_regulation of Localization of APOE 1 0.56 2.23 0.11
169 INT147009 Regulation of Gene_expression of S100b 2 0.07 0.34 0.1
170 INT309869 Regulation of Binding of Gsk3b 1 0.12 0.66 0.1
171 INT312871 Positive_regulation of Transcription of Gsk3b 2 0.29 0.15 0.09
172 INT117441 Negative_regulation of Regulation of Sgk1 1 0.43 0.19 0.09
173 INT300643 Positive_regulation of Binding of APOE 1 0.44 0.8 0.09
174 INT288642 Negative_regulation of Positive_regulation of Snca 1 0.07 0.93 0.09
175 INT44609 Negative_regulation of Positive_regulation of APOE 1 0.16 0.9 0.09
176 INT234926 Protein_catabolism of Gsk3b 2 0.58 1.33 0.08
177 INT82169 Negative_regulation of S100b 2 0.31 0.69 0.08
178 INT234906 Positive_regulation of Protein_catabolism of Gsk3b 2 0.33 1.33 0.08
179 INT205147 Regulation of Phosphorylation of APOE 1 0.06 0.34 0.07
180 INT97709 Positive_regulation of Localization of Apoe 1 0.68 1.02 0.07
181 INT292946 Positive_regulation of Localization of Snca 1 0.50 0.52 0.06
182 INT208336 Positive_regulation of Binding of Apoe 1 0.48 0.7 0.05
183 INT208333 Positive_regulation of Positive_regulation of Apoe 1 0.48 0.65 0.05
184 INT312877 Positive_regulation of Negative_regulation of Hdac6 1 0.45 0 0.05
185 INT180298 Regulation of Positive_regulation of S100B 3 0.39 1.09 0.04
186 INT336062 Regulation of Localization of Gsk3b 1 0.03 0.48 0.04
187 INT312888 Phosphorylation of Hdac6 1 0.73 0 0.03
188 INT326070 Regulation of Localization of APOE 1 0.58 1.21 0.03
189 INT191285 Positive_regulation of Localization of APOE 3 0.66 3.06 0
190 INT268625 Regulation of Transcription of Gsk3b 2 0.15 0 0
191 INT326073 Transcription of APOE 2 0.51 1.94 0
192 INT50081 Positive_regulation of Positive_regulation of APOE 2 0.49 0.18 0
193 INT283691 Binding of Aatf 2 0.03 0.19 0
194 INT312873 Negative_regulation of Gene_expression of Hdac6 1 0.38 0 0
195 INT200568 Negative_regulation of Regulation of S100b 1 0.01 1.03 0
196 INT312885 Binding of Hdac6 1 0.43 0 0
197 INT283704 Phosphorylation of Aatf 1 0.05 0.19 0
198 INT312874 Regulation of Phosphorylation of Hdac6 1 0.40 0 0
199 INT235488 Negative_regulation of Transcription of S100B 1 0.37 0.09 0
200 INT317275 Positive_regulation of Binding of Snca 1 0.37 0.53 0
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