GO:0048167

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Name regulation of synaptic plasticity
Categary Process
Go Slim No
Go Link GO:0048167
Unique Molecular Interactions 1008
Total Molecular Interactions 1373
Total Single Events 14328
Pain Genes Associated 53

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of synaptic plasticity. They are ordered first by their pain relevance and then by number of times they were reported for regulation of synaptic plasticity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33
2 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 0.76 8.19 6.66
3 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25
4 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23
5 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65
6 INT251146 Binding of Grin1 and Dlg2 1 0.36 1.95 3.16
7 INT101408 Binding of Grin1 and Olr1469 1 0.03 0.86 3.1
8 INT101407 Binding of Grin1 and Spr 1 0.14 0.86 3.09
9 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
10 INT152699 Bdnf Positive_regulation of Ltp 5 0.05 1.22 2.95
11 INT156381 Binding of Grin1 and Dlg4 1 0.39 0.86 2.9
12 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79
13 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
14 INT351444 Grin1 Positive_regulation of Gria2 1 0.22 1.5 2.64
15 INT128044 Bdnf Positive_regulation of Ephb1 2 0.31 1.89 2.57
16 INT340117 Binding of Bdnf and Pain1 1 0.01 2.48 2.55
17 INT317528 Ppp1r9b Regulation of Grin1 1 0.18 0.2 2.48
18 INT14687 Binding of Penk and Ppt1 1 0.41 0 2.46
19 INT156799 Gria1 Regulation of Grm8 1 0.11 1.29 2.45
20 INT251147 Binding of Grin2b and Dlg2 1 0.33 2.75 2.43
21 INT317526 Binding of Hint1 and Gipc1 1 0.00 0.25 2.38
22 INT284088 Binding of BDNF and NTRK2 5 0.41 3.4 2.37
23 INT107578 Kitl Negative_regulation of Grin2b 1 0.12 2.05 2.36
24 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21
25 INT251145 Binding of Grin2a and Dlg2 1 0.31 2.3 2.11
26 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
27 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
28 INT272616 Positive_regulation of Binding of Grin1 and Grin2a 2 0.30 1.36 1.8
29 INT122964 FSCN1 Positive_regulation of Bdnf 1 0.01 1.14 1.79
30 INT136273 NGF Regulation of Gene_expression of BDNF 2 0.41 1.14 1.78
31 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75
32 INT139156 Binding of Gria1 and Gria2 1 0.23 0.64 1.72
33 INT145098 NGF Positive_regulation of BDNF 1 0.66 1.33 1.67
34 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
35 INT131575 Grin1 Negative_regulation of Positive_regulation of Ephb1 1 0.28 0.31 1.58
36 INT168608 Binding of Grin2b and Mmp9 1 0.22 0.41 1.57
37 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55
38 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
39 INT166360 Negative_regulation of Crhr1 Negative_regulation of Positive_regulation of Pomc 1 0.02 0.36 1.5
40 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48
41 INT220058 NGF Positive_regulation of Gene_expression of BDNF 1 0.12 1.31 1.48
42 INT220059 NGF Positive_regulation of Positive_regulation of BDNF 1 0.11 1.31 1.48
43 INT140329 Grin1 Negative_regulation of Ltp 1 0.04 0.64 1.46
44 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
45 INT180767 Bdnf Positive_regulation of Gene_expression of Calca 1 0.17 0 1.45
46 INT180804 Bdnf Positive_regulation of Gene_expression of Sorbs1 1 0.01 0 1.44
47 INT180768 Bdnf Regulation of Localization of Trpv1 1 0.13 1.21 1.43
48 INT246519 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.25 0.08 1.42
49 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
50 INT138099 Binding of Grin2a and Insrr 1 0.01 0.36 1.39
51 INT167528 Ppt1 Negative_regulation of Gene_expression of Tac4 1 0.06 0.49 1.39
52 INT167529 Ppt1 Negative_regulation of Gene_expression of Trpv1 1 0.26 0.49 1.38
53 INT60993 Ntf4 Negative_regulation of Positive_regulation of CRTAC1 1 0.00 0 1.37
54 INT326194 Bdnf Regulation of Slc12a5 1 0.05 0.85 1.35
55 INT151770 Binding of P2RX3 and Ngf 1 0.18 0.9 1.35
56 INT250934 Binding of BDNF and NGF 3 0.39 0.62 1.34
57 INT151771 Binding of P2RX3 and Calca 1 0.04 0.89 1.34
58 INT107104 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.42 1.86 1.34
59 INT356317 Crhr1 Regulation of Gene_expression of Cea 1 0.18 0.65 1.33
60 INT356326 Crhr1 Regulation of Gene_expression of Helt 1 0.01 0.65 1.32
61 INT180771 Calca Regulation of Positive_regulation of Bdnf 1 0.18 0 1.32
62 INT317519 Grin1 Positive_regulation of Negative_regulation of Oprm1 1 0.14 0 1.31
63 INT96708 Bdnf Positive_regulation of Localization of SST 1 0.01 0 1.3
64 INT18659 Plat Regulation of ZC3H12D 1 0.02 0.1 1.29
65 INT154518 Binding of Ephb6 and Grin2b 1 0.21 0.24 1.28
66 INT280480 Binding of Bdnf and Ngfr 5 0.25 3.14 1.27
67 INT159655 Binding of BDNF and INSRR 2 0.00 1.25 1.26
68 INT155663 Positive_regulation of P2rx4 Positive_regulation of Localization of Bdnf 1 0.42 0.84 1.25
69 INT352269 Binding of Jund and Adora1 1 0.15 1.2 1.25
70 INT251142 Binding of Dlg4 and Grin2a 3 0.30 0.5 1.24
71 INT50386 Bdnf Regulation of Npy 1 0.21 0.47 1.24
72 INT50385 Bdnf Positive_regulation of Pomc 1 0.22 0.47 1.23
73 INT112105 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2b 2 0.40 0.89 1.2
74 INT334351 Bdnf Regulation of Positive_regulation of Ephb1 1 0.18 1.27 1.2
75 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19
76 INT107579 Kitl Negative_regulation of Grin2a 1 0.10 1.02 1.18
77 INT148437 Binding of Bdnf and Ngf 2 0.32 1.9 1.17
78 INT148435 Binding of Bdnf and Gdnf 2 0.35 1.9 1.17
79 INT60990 Bdnf Negative_regulation of Th 1 0.15 0 1.17
80 INT215648 Binding of Adora1 and Gabrd 1 0.03 0.06 1.16
81 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
82 INT317553 Binding of Car2 and Grin1 1 0.07 0 1.14
83 INT332776 FSCN1 Positive_regulation of Grin1 1 0.02 0.21 1.12
84 INT209088 Binding of Ceacam3 and Crhr1 1 0.34 1.26 1.11
85 INT132683 Bdnf Positive_regulation of Phosphorylation of Grin2a 1 0.00 0.93 1.11
86 INT122268 Binding of Grin2b and Grm5 1 0.40 0.52 1.1
87 INT269191 Binding of Grin1 and Grin3a 2 0.32 1.05 1.09
88 INT269189 Binding of Grin2a and Grin3a 2 0.25 1.05 1.09
89 INT317561 Binding of Grin1 and Oprm1 1 0.14 0.09 1.08
90 INT256294 Binding of Grin2b and Ephb1 1 0.28 1.11 1.08
91 INT87320 Ngf Regulation of Gene_expression of Bdnf 2 0.38 0.97 1.06
92 INT269193 Prkcg Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
93 INT269192 Ephb1 Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
94 INT269198 Prkaca Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
95 INT291966 Pag1 Positive_regulation of Gene_expression of Grin2b 1 0.19 1.91 1.06
96 INT317531 Regulation of Binding of Grin1 and Mors1 1 0.08 0.06 1.05
97 INT317534 Regulation of Binding of Camk2a and Grin1 1 0.20 0.06 1.05
98 INT256293 Binding of Grin2b and Insrr 1 0.01 1.06 1.05
99 INT269199 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.03 0.56 1.05
100 INT134534 Binding of Bdnf and Psds1 1 0.01 0 1.05
101 INT317535 Binding of Grin1 and Mors1 1 0.07 0.06 1.04
102 INT291964 Phex Regulation of Gene_expression of Grin2b 1 0.08 1.39 1.04
103 INT346835 Gene_expression of Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.27 1.07 1.03
104 INT160541 Binding of BDNF and PSIP1 4 0.49 1.94 1.02
105 INT224856 Binding of Bdnf and Eef2 1 0.14 0 1.02
106 INT269194 Ceacam3 Positive_regulation of Phosphorylation of Grin1 1 0.09 0.55 1.02
107 INT242642 Binding of BDNF and Ngfr 2 0.21 1.38 1.01
108 INT131889 gr Regulation of Gene_expression of Grin1 1 0.02 0 1.01
109 INT186161 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.11 1.05 1.01
110 INT353690 Binding of Grin2b and Ca2 1 0.14 1.17 1.01
111 INT317532 Grin1 Regulation of Negative_regulation of Oprm1 1 0.18 0.07 1
112 INT156510 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.03 0.98 0.98
113 INT344389 Ephb2 Positive_regulation of Phosphorylation of Grin2b 1 0.16 1.46 0.98
114 INT156508 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.22 0.98 0.98
115 INT353372 Dio1 Positive_regulation of Grin1 1 0.16 0 0.98
116 INT156380 Regulation of Binding of Grin1 and Dlg4 1 0.29 0.32 0.97
117 INT105668 Binding of AAVS1 and BDNF 1 0.08 0.94 0.95
118 INT354224 Bdnf Positive_regulation of Transcription of Accn3 1 0.09 1.04 0.95
119 INT258170 Binding of Adora1 and Ppap2a 1 0.05 0.26 0.94
120 INT338893 TNFSF14 Positive_regulation of Gene_expression of Gria1 1 0.07 0.59 0.94
121 INT132610 Bdnf Positive_regulation of Ntrk2 4 0.46 1.09 0.93
122 INT344381 Olfr360 Negative_regulation of Gene_expression of Grin2b 1 0.01 1.17 0.93
123 INT70802 Ngf Regulation of Ppt1 1 0.21 0.39 0.93
124 INT344390 Olfr360 Negative_regulation of Phosphorylation of Grin2b 1 0.01 1.17 0.93
125 INT215650 Binding of Adora1 and Drd1a 2 0.39 0.54 0.92
126 INT344388 Efnb1 Positive_regulation of Phosphorylation of Grin2b 1 0.40 1.45 0.92
127 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
128 INT251153 Dlg2 Positive_regulation of Gene_expression of Grin2a 1 0.40 0.6 0.92
129 INT251152 Dlg2 Positive_regulation of Localization of Grin2b 1 0.43 0.6 0.92
130 INT291962 Pag1 Negative_regulation of Gene_expression of Grin2b 1 0.17 1.56 0.92
131 INT72917 Binding of Crh and Crhr1 4 0.32 0.73 0.91
132 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
133 INT219037 Creb1 Positive_regulation of Transcription of Bdnf 2 0.43 1.07 0.9
134 INT281089 Binding of Gria1 and Ltp 1 0.25 0.6 0.9
135 INT108647 Binding of Grin2a and Camk1d 1 0.33 0.78 0.9
136 INT180772 Bdnf Regulation of Trpv1 1 0.11 0.29 0.9
137 INT180777 Bdnf Regulation of Gene_expression of Trpv1 1 0.18 0.29 0.9
138 INT108438 Grin2b Regulation of Pdyn 1 0.16 0.25 0.9
139 INT152700 Negative_regulation of Nfkb1 Negative_regulation of Bdnf 1 0.04 0.15 0.89
140 INT152701 Nfkb1 Negative_regulation of Bdnf 1 0.04 0.15 0.89
141 INT326663 Bdnf Regulation of Positive_regulation of Arc 1 0.16 1.46 0.88
142 INT152694 Negative_regulation of Nfkb1 Negative_regulation of Bdnf 1 0.24 0.15 0.88
143 INT48463 Bdnf Positive_regulation of Gene_expression of Sst 1 0.25 0 0.88
144 INT152695 Nfkb1 Negative_regulation of Bdnf 1 0.24 0.15 0.88
145 INT261783 Bdnf Regulation of Gene_expression of Slc12a5 1 0.09 0 0.87
146 INT52195 Sigmar1 Positive_regulation of Positive_regulation of Grin1 1 0.15 0 0.87
147 INT337899 Positive_regulation of MC3R Positive_regulation of Gene_expression of Bdnf 1 0.31 0 0.87
148 INT215596 Bdnf Positive_regulation of Negative_regulation of Slc12a5 1 0.14 0.76 0.86
149 INT326664 Bdnf Positive_regulation of Arc 1 0.27 1.07 0.86
150 INT326661 Bdnf Positive_regulation of Gene_expression of Arc 1 0.27 1.96 0.86
151 INT215646 Binding of Adora1 and P2rx2 1 0.13 0.51 0.85
152 INT270218 P2rx3 Positive_regulation of Pla2g4a 1 0.34 0.63 0.85
153 INT261786 Bdnf Negative_regulation of Slc12a5 1 0.14 0.05 0.85
154 INT304575 Creb1 Regulation of Gene_expression of Bdnf 1 0.04 1 0.84
155 INT256045 Binding of BDNF and Ntrk1 3 0.34 0.65 0.83
156 INT69084 Binding of Adrb1 and Positive_regulation of Positive_regulation of Pdpk1 1 0.02 0.08 0.83
157 INT127545 Gria1 Positive_regulation of Gene_expression of Gnptab 1 0.00 0.7 0.83
158 INT212290 Binding of Grin2a and Grin2b 2 0.20 1.36 0.82
159 INT140280 Negative_regulation of Binding of Adora2a and Grina 1 0.21 0.64 0.82
160 INT98479 Lif Regulation of Gene_expression of Grin1 1 0.04 0.35 0.82
161 INT340113 Comt Regulation of Bdnf 1 0.21 0.74 0.82
162 INT140281 Binding of Adora2a and Grina 1 0.19 0.64 0.82
163 INT271193 Creb1 Regulation of Bdnf 1 0.15 0.28 0.81
164 INT128042 Bdnf Positive_regulation of Phosphorylation of Ephb1 1 0.22 0.2 0.8
165 INT100559 Binding of Grin1 and LOC502940 1 0.13 0.61 0.8
166 INT180782 Bdnf Positive_regulation of Calca 1 0.16 0.77 0.8
167 INT54800 Grin1 Regulation of Gene_expression of Gh 1 0.01 0 0.79
168 INT60102 Adora1 Regulation of Localization of Calca 1 0.46 0 0.79
169 INT128041 Bdnf Positive_regulation of Trib3 1 0.10 0.29 0.79
170 INT214876 Ap3d1 Negative_regulation of Gria1 1 0.00 0.4 0.78
171 INT224280 Bdnf Positive_regulation of Creb1 3 0.30 0.62 0.77
172 INT72017 Binding of Adora2a and Ptprg 2 0.07 0 0.77
173 INT224281 Bdnf Regulation of Gene_expression of Gap43 1 0.36 0.4 0.77
174 INT110130 NR3C1 Regulation of ADORA1 1 0.04 0.73 0.77
175 INT76498 Binding of Tacr1 and Adora2a 1 0.09 0 0.77
176 INT232621 Binding of Gria1 and Psd 1 0.10 0.29 0.77
177 INT224283 Bdnf Regulation of Gene_expression of Calca 1 0.19 0.35 0.76
178 INT144547 Binding of Mecp2 and Sin3a 1 0.40 0.87 0.76
179 INT76499 Binding of Insr and Adora2a 1 0.08 0 0.76
180 INT82040 Adora2a Positive_regulation of Phosphorylation of Ppp1r1b 1 0.11 0 0.75
181 INT102086 TRNAI1 Negative_regulation of Positive_regulation of P2rx3 1 0.00 0.47 0.74
182 INT4915 Binding of Tac2 and Gipc1 1 0.01 0 0.74
183 INT311525 Binding of Gria1 and Ltp 1 0.00 0.1 0.73
184 INT296285 Binding of Car1 and Grin2b 1 0.14 0.32 0.72
185 INT82041 Positive_regulation of Adora2a Positive_regulation of Phosphorylation of Ppp1r1b 1 0.12 0 0.72
186 INT186160 Negative_regulation of Grin2b Negative_regulation of Grin1 1 0.37 0.5 0.72
187 INT317547 Src Positive_regulation of Positive_regulation of Grin1 1 0.17 0 0.72
188 INT296292 Binding of Car1 and Grin2a 1 0.14 0.32 0.72
189 INT290548 Positive_regulation of Crhr1 Positive_regulation of Etf1 1 0.01 0.38 0.72
190 INT296289 Grin2a Regulation of Negative_regulation of Kcnip3 1 0.30 0.3 0.72
191 INT296290 Binding of Car1 and Grin1 1 0.11 0.32 0.72
192 INT296282 Grin2b Regulation of Negative_regulation of Kcnip3 1 0.30 0.3 0.72
193 INT180765 Calca Regulation of Binding of Bdnf 1 0.15 0.15 0.72
194 INT296295 Binding of Grin1 and Grin2b 1 0.16 0.31 0.71
195 INT296298 Grin2b Regulation of Negative_regulation of Hmmr 1 0.03 0.29 0.71
196 INT281241 Positive_regulation of P2RX7 Negative_regulation of Gene_expression of P2rx3 1 0.03 0.79 0.71
197 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
198 INT190984 Binding of Scn2a1 and Gria1 1 0.03 0.08 0.71
199 INT296288 Grin2a Regulation of Negative_regulation of Hmmr 1 0.03 0.29 0.71
200 INT51433 Gria1 Positive_regulation of Eif3g 1 0.03 0 0.7

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of synaptic plasticity. They are ordered first by their pain relevance and then by number of times they were reported in regulation of synaptic plasticity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1
2 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82
3 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61
4 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24
5 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38
6 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68
7 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01
8 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48
9 INT67682 Localization of Bdnf 204 0.81 72.36 88.92
10 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12
11 INT92518 Gene_expression of Grin2b 131 0.78 65.52 80.91
12 INT29708 Gene_expression of Gria1 177 0.78 56.36 77.37
13 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42
14 INT47690 Regulation of Bdnf 118 0.62 53.02 64.5
15 INT90911 Positive_regulation of Phosphorylation of Grin1 62 0.70 27.45 59.26
16 INT7340 Regulation of Grin1 87 0.62 30.37 57.93
17 INT8071 Positive_regulation of Gria1 102 0.70 26.61 53.37
18 INT47680 Regulation of Gene_expression of Bdnf 92 0.62 41.61 53.24
19 INT4957 Negative_regulation of Grin1 87 0.59 24.51 53.21
20 INT66040 Positive_regulation of Bdnf 114 0.69 67.67 51.81
21 INT49520 Gene_expression of P2rx3 121 0.78 61.15 49.24
22 INT51627 Gene_expression of Grin2a 82 0.76 25.09 47.6
23 INT57021 Positive_regulation of Gene_expression of Grin1 62 0.70 24.77 47.31
24 INT47683 Negative_regulation of Bdnf 92 0.59 47.53 43.55
25 INT94029 Positive_regulation of Grin2b 58 0.70 24.2 42.52
26 INT16261 Transcription of Bdnf 101 0.72 49.41 40.64
27 INT92517 Gene_expression of Grin1 105 0.78 29.53 39.43
28 INT92515 Gene_expression of Grin2a 84 0.76 26.68 38.37
29 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14
30 INT11246 Binding of Grin1 65 0.48 14.53 36.93
31 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08
32 INT130479 Phosphorylation of Grin2b 28 0.77 34.82 34.97
33 INT52194 Positive_regulation of Grin1 83 0.69 25.09 34.76
34 INT40160 Positive_regulation of Adora1 74 0.70 26.36 33.03
35 INT57024 Regulation of Gene_expression of Grin1 32 0.62 9.77 32.6
36 INT93451 Positive_regulation of Gene_expression of Grin2b 43 0.70 29.09 31.89
37 INT114173 Phosphorylation of Gria1 27 0.82 33.73 31.24
38 INT49001 Regulation of Gria1 51 0.56 18.28 31.22
39 INT106554 Positive_regulation of Gene_expression of Bdnf 73 0.70 42.58 30.77
40 INT106540 Negative_regulation of Phosphorylation of Grin1 15 0.58 9.32 29.13
41 INT102206 Regulation of Bdnf 37 0.62 28.54 28.78
42 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54
43 INT67620 Negative_regulation of Gene_expression of Bdnf 53 0.59 22.45 28.5
44 INT48853 Positive_regulation of BDNF 82 0.69 43.92 27.99
45 INT14575 Positive_regulation of Ppt1 60 0.70 9.97 27.4
46 INT80470 Negative_regulation of Gene_expression of Grin1 33 0.59 10.22 27.15
47 INT47685 Positive_regulation of Positive_regulation of Bdnf 32 0.70 20.05 27.03
48 INT97 Negative_regulation of Adrb1 102 0.59 32.44 26.9
49 INT56053 Negative_regulation of Bdnf 77 0.58 64.4 26.83
50 INT107577 Negative_regulation of Grin2b 32 0.59 12.35 24.88
51 INT96557 Binding of Bdnf 46 0.47 21.74 24.26
52 INT76249 Gene_expression of Gria1 67 0.75 15.07 22.78
53 INT113925 Localization of Bdnf 59 0.79 24.03 22.76
54 INT4890 Gene_expression of Ppt1 51 0.77 8.93 21.83
55 INT49623 Negative_regulation of Gria1 39 0.59 12.4 21.59
56 INT4894 Transcription of Ppt1 34 0.67 5.93 21.06
57 INT129987 Phosphorylation of Gria1 63 0.80 20.65 21.02
58 INT102281 Positive_regulation of Gene_expression of Grin2b 27 0.70 10.38 20.84
59 INT102203 Transcription of Bdnf 35 0.71 18.26 20.59
60 INT91916 Gene_expression of P2rx3 51 0.78 21.2 19.05
61 INT90612 Positive_regulation of Grin2a 33 0.65 15.11 18.84
62 INT103469 Positive_regulation of Gene_expression of BDNF 59 0.67 24.39 18.36
63 INT50420 Transcription of Grin1 30 0.71 13.21 18.28
64 INT29709 Positive_regulation of Gene_expression of Gria1 36 0.69 9.43 17.83
65 INT106556 Negative_regulation of Gene_expression of Bdnf 42 0.59 34.71 17.64
66 INT63928 Negative_regulation of Grin1 51 0.56 11.81 17.57
67 INT102903 Regulation of Gene_expression of Bdnf 35 0.62 20.1 17.42
68 INT78233 Positive_regulation of P2rx3 36 0.56 21.49 17.25
69 INT16624 Localization of Grin1 38 0.79 8.46 17.15
70 INT93037 Regulation of Grin2b 26 0.57 11.9 16.92
71 INT92514 Regulation of Grin2b 22 0.50 11.07 16.92
72 INT88356 Negative_regulation of Positive_regulation of Grin1 16 0.58 4.72 16.58
73 INT96299 Positive_regulation of Localization of Bdnf 35 0.70 15.67 16.09
74 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
75 INT9750 Positive_regulation of Rara 39 0.66 12.44 15.83
76 INT9751 Localization of Crhr1 26 0.78 10.47 15.69
77 INT69652 Regulation of P2rx3 26 0.61 17.17 15.4
78 INT25872 Positive_regulation of Adora1 19 0.69 4.9 15.01
79 INT114172 Positive_regulation of Phosphorylation of Gria1 8 0.63 15.73 14.99
80 INT163479 Binding of Bdnf 36 0.48 25.77 14.83
81 INT14647 Positive_regulation of Grin2a 26 0.67 4.69 14.8
82 INT8794 Negative_regulation of Ppt1 35 0.57 6.44 14.52
83 INT95 Positive_regulation of Adrb1 34 0.62 11.95 14.41
84 INT61864 Regulation of Gene_expression of Gria1 24 0.62 13.27 14.3
85 INT15042 Gene_expression of Adora2a 37 0.77 3.77 14.24
86 INT92513 Regulation of Grin1 26 0.59 9.12 13.94
87 INT108063 Gene_expression of Adora2a 29 0.78 13.11 13.78
88 INT7342 Positive_regulation of Positive_regulation of Grin1 18 0.50 9.22 13.76
89 INT49538 Binding of Gria1 22 0.47 2.66 13.35
90 INT100655 Regulation of BDNF 51 0.60 21.49 13.14
91 INT47692 Negative_regulation of Positive_regulation of Bdnf 18 0.59 9.64 13.14
92 INT103996 Negative_regulation of Phosphorylation of Grin2b 11 0.58 7.81 12.85
93 INT119089 Regulation of Phosphorylation of Grin1 17 0.61 3.1 12.82
94 INT50227 Positive_regulation of Adora2a 32 0.50 5.17 12.75
95 INT109223 Negative_regulation of Cdk5 14 0.59 3.27 12.73
96 INT103997 Phosphorylation of Grin2a 17 0.64 10.75 12.67
97 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55
98 INT100799 Negative_regulation of Grin2a 27 0.57 7.33 12.2
99 INT112103 Binding of Grin1 28 0.48 4.21 12.08
100 INT111948 Positive_regulation of Gria1 23 0.61 7.55 12.03
101 INT56048 Positive_regulation of Transcription of Bdnf 24 0.70 8.33 11.83
102 INT51625 Regulation of Gene_expression of Grin2a 12 0.60 3.28 11.6
103 INT72784 Positive_regulation of Adora2a 26 0.70 16.52 11.47
104 INT104039 Positive_regulation of Crhr1 15 0.70 8.34 10.99
105 INT130475 Positive_regulation of Phosphorylation of Grin2b 8 0.47 11.52 10.96
106 INT78579 Negative_regulation of P2rx3 23 0.59 10.13 10.78
107 INT19155 Binding of Adora1 25 0.47 6.41 10.72
108 INT72579 Localization of BDNF 56 0.80 14.84 10.65
109 INT51626 Transcription of Grin2a 16 0.68 1.65 10.5
110 INT93036 Negative_regulation of Grin2a 23 0.50 7.1 10.32
111 INT64193 Regulation of Grin2a 19 0.54 2.98 10.31
112 INT8072 Localization of Gria1 17 0.75 2.62 10.04
113 INT59 Regulation of Adrb1 25 0.42 8.32 9.78
114 INT15449 Positive_regulation of Plat 32 0.69 12.76 9.71
115 INT96298 Negative_regulation of Gria1 25 0.57 10.61 9.7
116 INT103474 Regulation of Gene_expression of BDNF 40 0.60 12.14 9.65
117 INT80006 Regulation of Gene_expression of Grin2b 8 0.57 3.75 9.62
118 INT29988 Gene_expression of Mecp2 27 0.78 5.45 9.47
119 INT78769 Regulation of Grin2a 16 0.58 5.22 9.28
120 INT136012 Regulation of Transcription of Bdnf 6 0.45 2.76 9.2
121 INT114406 Gene_expression of Adora1 28 0.72 6.83 9.13
122 INT101602 Positive_regulation of Cdk5 15 0.70 4.1 8.96
123 INT7572 Regulation of Crhr1 8 0.45 5.6 8.93
124 INT121987 Phosphorylation of Grin1 11 0.80 4.73 8.88
125 INT78578 Localization of P2rx3 21 0.78 9.55 8.86
126 INT108931 Negative_regulation of BDNF 38 0.59 19.61 8.84
127 INT96 Binding of Adrb1 18 0.48 2.8 8.52
128 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
129 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45
130 INT24651 Positive_regulation of Transcription of Ppt1 12 0.47 2.88 8.42
131 INT23209 Binding of Adora2a 17 0.38 2.04 8.35
132 INT157580 Phosphorylation of Cdk5 4 0.77 0.73 8.33
133 INT75998 Transcription of BDNF 61 0.69 11.03 8.27
134 INT112104 Binding of Grin2b 21 0.44 6.78 8.16
135 INT117642 Regulation of Gene_expression of Grin1 18 0.53 7.09 8.08
136 INT9350 Regulation of ADORA1 9 0.12 1.53 7.79
137 INT54755 Negative_regulation of Adora2a 17 0.58 2.7 7.75
138 INT135113 Localization of Grin1 18 0.73 3.73 7.69
139 INT7570 Transcription of Crhr1 7 0.66 6.6 7.6
140 INT101699 Regulation of Adora1 14 0.61 3.7 7.59
141 INT74326 Gene_expression of Crhr1 25 0.66 9.7 7.48
142 INT80161 Positive_regulation of Crhr1 13 0.67 9.66 7.33
143 INT110705 Positive_regulation of Positive_regulation of Grin1 11 0.69 4.7 7.33
144 INT102080 Positive_regulation of P2rx3 20 0.67 6.91 7.3
145 INT102207 Positive_regulation of Transcription of Bdnf 13 0.69 5.49 7.18
146 INT10513 Gene_expression of Plat 44 0.76 19.49 7.17
147 INT57023 Negative_regulation of Gene_expression of Gria1 20 0.58 6.92 7.17
148 INT40159 Negative_regulation of Adora1 13 0.51 3.51 7.13
149 INT5774 Regulation of Ppt1 22 0.60 4.97 7.1
150 INT76197 Positive_regulation of ADORA1 7 0.59 5.06 7
151 INT132860 Binding of BDNF 33 0.47 14.7 6.99
152 INT11652 Gene_expression of Rara 30 0.58 24.96 6.98
153 INT9167 Binding of Adora1 6 0.40 0.53 6.9
154 INT139149 Binding of Gria1 22 0.37 5.71 6.88
155 INT76255 Gene_expression of ADORA1 11 0.78 2.51 6.85
156 INT78232 Binding of P2rx3 25 0.41 6.26 6.78
157 INT120298 Negative_regulation of Phosphorylation of Gria1 6 0.57 8.99 6.68
158 INT87939 Gene_expression of P2RX3 23 0.75 6.15 6.62
159 INT9753 Positive_regulation of Localization of Crhr1 8 0.49 1.72 6.55
160 INT100926 Positive_regulation of Gene_expression of Grin2a 11 0.63 3.24 6.41
161 INT17262 Negative_regulation of Plat 17 0.59 15.14 6.36
162 INT85655 Gene_expression of Crhr1 17 0.68 9.34 6.31
163 INT103477 Negative_regulation of Gene_expression of BDNF 23 0.52 10.63 6.26
164 INT144539 Phosphorylation of Mecp2 3 0.82 6.18 6.2
165 INT100658 Negative_regulation of Positive_regulation of Grin2b 7 0.41 1.39 6.17
166 INT91065 Regulation of Transcription of Bdnf 13 0.62 12.48 6.13
167 INT135359 Positive_regulation of Mecp2 4 0.70 4.35 6.05
168 INT74593 Transcription of Grin2b 10 0.66 1.21 5.98
169 INT127556 Positive_regulation of Cdk5 35 0.70 19.6 5.95
170 INT94927 Transcription of Gria1 12 0.69 3.14 5.94
171 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
172 INT4888 Positive_regulation of Gene_expression of Ppt1 9 0.54 2.78 5.83
173 INT95475 Positive_regulation of P2RX3 13 0.67 6.28 5.82
174 INT60724 Gene_expression of Psen2 30 0.72 27 5.79
175 INT130472 Negative_regulation of Phosphorylation of Grin2b 4 0.40 4.4 5.78
176 INT67693 Binding of Grin2a 9 0.38 1.74 5.68
177 INT56047 Negative_regulation of Transcription of Bdnf 16 0.59 8.02 5.67
178 INT101604 Regulation of Cdk5 10 0.61 2.2 5.53
179 INT55353 Negative_regulation of Positive_regulation of Ppt1 9 0.57 0.31 5.37
180 INT135473 Negative_regulation of Gene_expression of Grin1 14 0.47 5.47 5.36
181 INT83014 Binding of Adora2a 13 0.48 5.57 5.33
182 INT127353 Regulation of Phosphorylation of Grin2b 5 0.45 1.6 5.29
183 INT130478 Localization of Grin2b 11 0.75 2.49 5.28
184 INT208108 Localization of Grin2a 19 0.70 1.5 5.22
185 INT110666 Phosphorylation of Bdnf 12 0.69 5.67 5.21
186 INT92541 Localization of Grin2b 11 0.75 2.85 5.14
187 INT19549 Binding of Grin2a 12 0.45 1.24 5.09
188 INT67681 Negative_regulation of Localization of Bdnf 12 0.50 4.37 5.07
189 INT89664 Negative_regulation of Adora2a 11 0.59 7.81 5.07
190 INT135474 Negative_regulation of Gene_expression of Grin2a 7 0.39 6.94 4.89
191 INT51468 Regulation of Adora2a 8 0.48 1.5 4.84
192 INT111947 Positive_regulation of Gene_expression of Grin2a 7 0.68 1.75 4.84
193 INT18245 Negative_regulation of Localization of Crhr1 4 0.17 0.28 4.81
194 INT7568 Negative_regulation of Crhr1 8 0.43 4.63 4.77
195 INT79505 Binding of Grin2b 9 0.36 1.43 4.61
196 INT91917 Negative_regulation of P2rx3 11 0.59 6.56 4.51
197 INT93035 Negative_regulation of Transcription of Grin1 6 0.41 2.29 4.39
198 INT111404 Regulation of Positive_regulation of Grin1 5 0.56 2.49 4.31
199 INT170348 Regulation of Gene_expression of Grin2b 8 0.60 2.29 4.25
200 INT113926 Positive_regulation of Localization of Bdnf 7 0.56 3.15 4.25
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