GO:0048240

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Name sperm capacitation
Categary Process
Go Slim No
Go Link GO:0048240
Unique Molecular Interactions 273
Total Molecular Interactions 338
Total Single Events 2281
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for sperm capacitation. They are ordered first by their pain relevance and then by number of times they were reported for sperm capacitation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
2 INT130625 Prkcg Regulation of Prkaca 1 0.23 1.32 3.87
3 INT143946 Binding of Pebp1 and Mastl 1 0.00 2.04 3.82
4 INT298456 Prkaca Positive_regulation of Phosphorylation of Adarb1 1 0.00 1.86 2.85
5 INT121746 Prkaca Positive_regulation of Ephb1 2 0.23 0.92 2.35
6 INT281084 Prkaca Positive_regulation of Mapk1 2 0.25 0 2.06
7 INT26221 Calca Regulation of Gt(pU21)50Imeg 1 0.01 0 2.02
8 INT213968 Binding of Calca and Mthfd1 1 0.05 0.16 1.99
9 INT104855 Prkaca Regulation of TRPV1 3 0.06 1.52 1.92
10 INT112514 Binding of Prkaca and Trib3 1 0.03 1.18 1.9
11 INT186432 Prkaca Regulation of Creb1 1 0.14 0.45 1.9
12 INT112517 Binding of Ephb1 and Prkaca 3 0.18 0.58 1.85
13 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82
14 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75
15 INT139433 Binding of Prkaca and Prkca 1 0.37 0.13 1.67
16 INT122286 Prkaca Negative_regulation of Negative_regulation of Calca 1 0.12 0.54 1.63
17 INT195930 OPRM1 Regulation of Prkaca 1 0.01 0 1.59
18 INT8734 Pebp1 Positive_regulation of Oprd1 1 0.01 0 1.54
19 INT121741 Prkaca Negative_regulation of Positive_regulation of Creb1 1 0.10 0.2 1.49
20 INT276686 Calca Regulation of Nav1 1 0.26 0.74 1.45
21 INT84434 Calca Negative_regulation of Negative_regulation of Hrh1 1 0.06 0.19 1.44
22 INT78974 Binding of Prkcg and Prkaca 2 0.31 0.35 1.4
23 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38
24 INT124926 Negative_regulation of Prkaca Negative_regulation of Localization of Pag1 1 0.00 0.61 1.3
25 INT22501 Binding of Calca and Pth 1 0.21 0.07 1.28
26 INT195929 Binding of OPRM1 and Prkaca 1 0.02 0.33 1.27
27 INT141244 Fos Regulation of Prkaca 1 0.18 0.07 1.24
28 INT195926 Prkaca Positive_regulation of Trpv1 1 0.10 0.44 1.24
29 INT75229 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.44 0 1.22
30 INT151454 Binding of Calca and Insrr 1 0.02 0.31 1.22
31 INT76163 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.02 0.08 1.22
32 INT141245 Prkaca Regulation of Gene_expression of Th 1 0.15 0.17 1.17
33 INT85780 Prkaca Regulation of Prkcg 1 0.29 0.47 1.17
34 INT338053 F2r Positive_regulation of Localization of Calca 1 0.06 0.47 1.15
35 INT141979 Calca Negative_regulation of Gene_expression of Il1b 1 0.40 0.62 1.13
36 INT130627 Gnas Regulation of Prkaca 1 0.00 0 1.13
37 INT282065 Binding of Calca and Ngf 1 0.14 0.85 1.11
38 INT269200 Prkaca Positive_regulation of Phosphorylation of Ceacam3 1 0.03 0.65 1.09
39 INT352468 Calca Positive_regulation of Prkaca 1 0.11 0.8 1.08
40 INT96906 Plxna3 Regulation of Regulation of Prkaca 1 0.17 0.71 1.08
41 INT269198 Prkaca Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
42 INT269199 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.03 0.56 1.05
43 INT130167 Trpv1 Regulation of Localization of Calca 2 0.38 0.69 1.03
44 INT240453 Prkcg Positive_regulation of Positive_regulation of Prkaca 1 0.23 0.63 1.01
45 INT240455 Ephb1 Positive_regulation of Positive_regulation of Prkaca 1 0.22 0.63 1.01
46 INT186161 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.11 1.05 1.01
47 INT298298 Calca Negative_regulation of Gene_expression of Runx1 1 0.19 0.33 1
48 INT320021 Prkaca Regulation of Positive_regulation of Kcnma1 1 0.00 0.54 1
49 INT298274 Gene_expression of Runx1 Negative_regulation of Calca 1 0.19 0.33 1
50 INT276864 Positive_regulation of Gpr65 Positive_regulation of Prkaca 1 0.16 0.74 0.97
51 INT42482 Binding of Cpe and Pebp1 1 0.02 0 0.95
52 INT252877 Prkaca Positive_regulation of Regulation of Grip2 1 0.01 0.22 0.94
53 INT331109 Tpnr1 Regulation of Gene_expression of Calca 1 0.06 0.97 0.94
54 INT252878 Prkaca Regulation of Regulation of Grip2 1 0.01 0.22 0.94
55 INT252880 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Tacr1 1 0.02 0.29 0.92
56 INT195927 Binding of Prkaca and Trpv1 1 0.07 0.28 0.92
57 INT252876 Positive_regulation of Prkaca Regulation of Gene_expression of Tacr1 1 0.01 0.28 0.89
58 INT196834 Prkaca Positive_regulation of Phosphorylation of Ppp1r1b 2 0.15 0 0.87
59 INT151779 Calca Positive_regulation of Transcription of P2rx7 1 0.02 0.54 0.87
60 INT112914 Ppp1r1b Negative_regulation of Prkaca 3 0.22 0.13 0.86
61 INT213976 Calca Negative_regulation of Gene_expression of Il2 1 0.03 0.25 0.86
62 INT351323 Nts Regulation of Localization of Calca 1 0.01 0.6 0.85
63 INT185937 NOS2 Regulation of Prkaca 1 0.03 1.08 0.82
64 INT78972 Prkaca Regulation of Ina 1 0.11 0.09 0.82
65 INT103178 Mastl Positive_regulation of Localization of Calca 1 0.13 0.36 0.81
66 INT213972 Calca Regulation of Mthfd1 1 0.05 0.19 0.8
67 INT40610 Binding of Prkaca and Oprl1 1 0.02 0.09 0.8
68 INT131646 Ngf Positive_regulation of Localization of Calca 1 0.21 0.35 0.8
69 INT186439 Prkaca Regulation of Phosphorylation of Creb1 1 0.06 0.08 0.79
70 INT240454 Ephb1 Regulation of Prkaca 1 0.14 0.51 0.79
71 INT91239 Prkaca Regulation of Negative_regulation of Oprm1 1 0.43 0 0.76
72 INT69692 Helt Regulation of Prkaca 1 0.00 0.33 0.76
73 INT262563 Negative_regulation of Pax3 Regulation of Calca 1 0.01 0.75 0.76
74 INT262569 Pax3 Regulation of Calca 1 0.00 0.75 0.76
75 INT262578 Prkaca Positive_regulation of Localization of Calca 1 0.03 0.71 0.75
76 INT196799 Prkaca Positive_regulation of Phosphorylation of Trh 1 0.02 0 0.74
77 INT147278 Negative_regulation of Calca Positive_regulation of Th 1 0.41 0.76 0.74
78 INT147277 Calca Positive_regulation of Th 1 0.48 0.76 0.74
79 INT142507 Binding of Calca and Ramp1 1 0.31 0.48 0.73
80 INT244025 Prkaca Regulation of Phosphorylation of Gabrg1 1 0.08 0.18 0.72
81 INT351350 Prkaca Regulation of Lpar1 1 0.04 0.58 0.72
82 INT338057 Positive_regulation of F2r Positive_regulation of Localization of Calca 1 0.05 0.28 0.71
83 INT148449 Gene_expression of Inhbe Positive_regulation of Prkaca 1 0.05 0.68 0.71
84 INT161297 Ppp1r1b Negative_regulation of Prkaca 1 0.10 0.16 0.7
85 INT262571 Phosphorylation of Trpv1 Positive_regulation of Localization of Calca 1 0.17 0.71 0.7
86 INT186162 Phosphorylation of Prkaca Positive_regulation of Phosphorylation of Prkcg 1 0.04 0.22 0.7
87 INT48032 Binding of Avp and Pebp1 1 0.00 0 0.68
88 INT48031 Binding of Oxt and Pebp1 1 0.01 0 0.68
89 INT169217 Binding of Pebp1 and Coc 1 0.00 0.22 0.67
90 INT109717 Calca Negative_regulation of Mpo 1 0.16 0.8 0.67
91 INT262576 Binding of Calca and Trpv1 1 0.13 1.05 0.66
92 INT150754 GTS Negative_regulation of Gene_expression of Prkaca 1 0.32 0.08 0.65
93 INT221847 Binding of Calca and Ntrk1 1 0.03 0.9 0.65
94 INT235881 Prkaca Positive_regulation of Creb1 2 0.10 0.16 0.64
95 INT104858 Prkaca Negative_regulation of Negative_regulation of TRPV1 2 0.10 0.41 0.64
96 INT112513 Binding of Prkaca and Prkce 1 0.04 0.4 0.64
97 INT102863 Prkaca Regulation of Srgn 1 0.50 0.05 0.64
98 INT145637 Calca Positive_regulation of P2rx3 1 0.33 0.7 0.64
99 INT151783 Regulation of Binding of Calca and P2rx1 1 0.42 0.51 0.64
100 INT151778 Binding of Calca and P2rx1 1 0.35 0.5 0.64
101 INT65256 Pebp1 Regulation of Gene_expression of Basp1 1 0.00 0.05 0.64
102 INT281081 Prkaca Positive_regulation of Gene_expression of Adcy1 1 0.12 0 0.63
103 INT196877 Trpv1 Positive_regulation of Localization of Calca 1 0.11 0.41 0.62
104 INT324065 Ptger2 Positive_regulation of Prkaca 2 0.24 0.63 0.61
105 INT151780 Calca Positive_regulation of Camkk2 1 0.01 0.48 0.61
106 INT281086 Prkaca Positive_regulation of Mdk 1 0.08 0 0.61
107 INT244055 Prkaca Regulation of Gabrg1 1 0.08 0 0.58
108 INT102864 Prkaca Regulation of Twist1 1 0.48 0.05 0.58
109 INT356320 ORF61 Positive_regulation of Positive_regulation of Prkaca 1 0.01 0.05 0.57
110 INT296472 Camk2a Positive_regulation of Prkaca 1 0.09 0.32 0.57
111 INT116369 Binding of Calca and Atp8a2 1 0.02 0.38 0.56
112 INT261485 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Ephb1 1 0.05 0.12 0.56
113 INT103184 Prkaca Positive_regulation of Phosphorylation of CRTC1 1 0.01 0.57 0.55
114 INT296293 Prkaca Regulation of Positive_regulation of Creb1 1 0.16 0.62 0.55
115 INT296291 Prkaca Regulation of Localization of Calm3 1 0.09 0.62 0.55
116 INT296273 Prkaca Regulation of Localization of Camk4 1 0.16 0.62 0.55
117 INT89059 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Trpv1 1 0.07 0.16 0.54
118 INT87559 Vip Positive_regulation of Prkaca 1 0.28 0 0.52
119 INT87557 Crh Positive_regulation of Prkaca 1 0.27 0 0.52
120 INT338045 F2r Regulation of Localization of Calca 1 0.03 0.05 0.52
121 INT196830 Arpp21 Regulation of Prkaca 1 0.01 0 0.52
122 INT303720 Prkaca Regulation of Bdkrb1 1 0.02 0.33 0.52
123 INT89058 Prkaca Regulation of Phosphorylation of Trpv1 1 0.04 0.35 0.51
124 INT196824 Ppp1r1b Regulation of Prkaca 1 0.10 0 0.51
125 INT342689 Ptger4 Positive_regulation of Prkaca 1 0.03 0.24 0.51
126 INT87558 Calca Positive_regulation of Prkaca 1 0.35 0 0.51
127 INT262565 Prkaca Regulation of Negative_regulation of Trpv1 1 0.05 0.21 0.5
128 INT243998 Binding of Prkaca and Dnm1 1 0.11 0.24 0.49
129 INT244037 Positive_regulation of Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
130 INT244021 Positive_regulation of Binding of Cacnb3 and Prkaca 1 0.02 0.24 0.49
131 INT243999 Positive_regulation of Binding of Prkaca and Dnm1 1 0.14 0.24 0.49
132 INT244036 Binding of Cacnb3 and Prkaca 1 0.01 0.24 0.49
133 INT244035 Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
134 INT342693 Binding of Prkaca and Gopc 1 0.01 0.23 0.48
135 INT147279 Binding of Calca and Pecam1 1 0.33 0.4 0.47
136 INT296451 Prkaca Regulation of Phosphorylation of Rbm39 1 0.00 0.27 0.47
137 INT320223 Tg(CAG-EGFP)D4Nagy Positive_regulation of Localization of Calca 1 0.08 0.08 0.46
138 INT235404 Positive_regulation of RTCA Positive_regulation of Positive_regulation of Prkaca 1 0.00 0.22 0.45
139 INT153994 Regulation of Prkaca Regulation of TRPV1 1 0.02 0.46 0.44
140 INT151781 Calca Positive_regulation of Gene_expression of P2rx1 1 0.50 0.07 0.44
141 INT78975 Positive_regulation of Prkaca Regulation of Ina 1 0.09 0 0.43
142 INT326458 Runx1 Negative_regulation of Gene_expression of Calca 1 0.18 0.05 0.43
143 INT102862 Prkaca Regulation of Phosphorylation of Twist1 1 0.19 0.1 0.42
144 INT196821 Phosphorylation of Ppp1r1b Positive_regulation of Prkaca 1 0.09 0 0.41
145 INT78971 Positive_regulation of Prkaca Positive_regulation of Ina 1 0.09 0.09 0.41
146 INT17059 Binding of DLD and Oxt 1 0.03 0.22 0.41
147 INT196797 Trh Negative_regulation of Prkaca 1 0.01 0 0.41
148 INT196828 Prkaca Positive_regulation of Ppp2ca 1 0.20 0 0.4
149 INT50624 Binding of Pebp1 and Opcml 2 0.13 0 0.38
150 INT150290 Grk1 Positive_regulation of Localization of Calca 1 0.10 0.53 0.38
151 INT235880 Binding of Mtap2 and Prkaca 1 0.07 0.41 0.38
152 INT356284 Ptger2 Positive_regulation of Prkaca 1 0.00 0.39 0.37
153 INT113289 TRPV1 Regulation of Phosphorylation of Prkaca 1 0.02 0.1 0.37
154 INT85778 Rb1 Regulation of Prkaca 1 0.00 0.38 0.36
155 INT235861 Binding of Prkaca and Akap5 1 0.20 0 0.35
156 INT306692 Prkaca Regulation of Positive_regulation of Nav1 1 0.13 0.06 0.35
157 INT215173 Prkaca Positive_regulation of Positive_regulation of Ptger2 1 0.06 0 0.33
158 INT112917 Nts Negative_regulation of Negative_regulation of Prkaca 1 0.20 0 0.33
159 INT104856 Prkaca Positive_regulation of Phosphorylation of TRPV1 1 0.11 0.23 0.33
160 INT112918 Phospho1 Negative_regulation of Prkaca 1 0.01 0 0.33
161 INT104857 Prkaca Negative_regulation of Localization of TRPV1 1 0.10 0.23 0.33
162 INT126852 Prkaca Positive_regulation of Creb1 1 0.27 0.09 0.32
163 INT235877 Prkaca Regulation of Transcription of Slc6a4 1 0.06 0.13 0.31
164 INT156632 Prkaca Regulation of Scn10a 1 0.13 0.67 0.3
165 INT196825 Prkaca Positive_regulation of Phosphorylation of Ppp2ca 1 0.20 0 0.29
166 INT196831 Positive_regulation of Prkaca Positive_regulation of Ppp2ca 1 0.20 0 0.29
167 INT196814 Negative_regulation of Prkaca Positive_regulation of Ppp2ca 1 0.17 0 0.29
168 INT168513 Prkaca Positive_regulation of Phosphorylation of Trpv1 1 0.22 0.11 0.29
169 INT122312 Prkaca Regulation of Kcnk3 1 0.13 0.28 0.28
170 INT283732 Prkaca Positive_regulation of Creb1 1 0.03 0 0.28
171 INT196695 Prkaca Positive_regulation of CFTR 1 0.46 0.13 0.27
172 INT241969 Grm8 Positive_regulation of Prkaca 1 0.05 0.35 0.27
173 INT352931 Prkaca Regulation of TP53 1 0.13 1.01 0.26
174 INT352930 Prkaca Regulation of Phosphorylation of TP53 1 0.13 1.02 0.26
175 INT241965 Prkaca Negative_regulation of Grm8 1 0.03 0.36 0.26
176 INT149356 Prkaca Negative_regulation of Raf1 1 0.10 0.08 0.25
177 INT241970 Acpt Positive_regulation of Positive_regulation of Prkaca 1 0.05 0.36 0.24
178 INT71254 MMD Negative_regulation of Prkaca 1 0.00 0 0.24
179 INT356098 Prkca Regulation of Prkaca 1 0.01 0.11 0.24
180 INT291448 Prkaca Regulation of Gene_expression of Kcnn2 1 0.04 0 0.23
181 INT291447 Bdnf Positive_regulation of Prkaca 1 0.04 0 0.23
182 INT272753 Positive_regulation of Prkaca Positive_regulation of EGFR 1 0.01 0 0.23
183 INT276046 Negative_regulation of Prkaca Positive_regulation of Phosphorylation of Ppp1r1b 1 0.15 0.11 0.23
184 INT196823 Adcy5 Positive_regulation of Prkaca 1 0.13 0 0.22
185 INT231036 Negative_regulation of Prkaca Negative_regulation of Positive_regulation of Sec22b 1 0.01 0 0.22
186 INT112920 Nts Positive_regulation of Phosphorylation of Prkaca 1 0.24 0 0.21
187 INT110384 Binding of Prkaca and Akap11 1 0.08 0.31 0.2
188 INT244054 Prkaca Regulation of Neurod1 1 0.02 0.06 0.19
189 INT215167 Phosphorylation of Prkaca Positive_regulation of P2rx2 1 0.06 0.13 0.18
190 INT106334 Olr1254 Positive_regulation of Prkaca 1 0.01 0 0.18
191 INT250052 Prkaca Regulation of Gria2 1 0.05 0 0.17
192 INT110385 Binding of Prkaca and Trpv1 1 0.14 0.28 0.17
193 INT219597 Prkaca Positive_regulation of Pde4d 1 0.29 0 0.15
194 INT329985 Positive_regulation of Prkaca Positive_regulation of Positive_regulation of Mapk14 1 0.15 0.87 0.15
195 INT245552 Runx1 Negative_regulation of Calca 1 0.33 0.65 0.15
196 INT350069 Prkaca Positive_regulation of Hmox1 1 0.05 0.2 0.15
197 INT145055 Pebp1 Negative_regulation of Localization of Nr1i3 1 0.14 0.33 0.14
198 INT244051 Ppp1ca Regulation of Prkaca 1 0.00 0.18 0.14
199 INT190747 Adcyap1 Regulation of Positive_regulation of Prkaca 1 0.05 0 0.14
200 INT244017 Prkaca Positive_regulation of Phosphorylation of Gabrg1 1 0.09 0.17 0.13

Single Events

The table below shows the top 100 pain related interactions that have been reported for sperm capacitation. They are ordered first by their pain relevance and then by number of times they were reported in sperm capacitation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5008 Localization of Calca 204 0.81 80.35 125.16
2 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75
3 INT52651 Positive_regulation of Prkaca 136 0.67 40.82 99.16
4 INT15898 Positive_regulation of Prkaca 199 0.70 50.89 87.54
5 INT49111 Negative_regulation of Prkaca 102 0.59 27.44 71.77
6 INT53964 Negative_regulation of Prkaca 131 0.58 38.76 69.52
7 INT97674 Positive_regulation of Localization of Calca 70 0.69 27.71 51.79
8 INT66383 Phosphorylation of Prkaca 143 0.80 30.85 43.38
9 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17
10 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45
11 INT89055 Phosphorylation of Prkaca 60 0.61 13.41 32.49
12 INT22499 Regulation of Calca 42 0.62 17.32 28.02
13 INT66381 Regulation of Prkaca 40 0.62 13.38 27.96
14 INT96904 Regulation of Prkaca 33 0.44 10.86 24.51
15 INT89805 Gene_expression of Prkaca 45 0.77 11.03 20.77
16 INT35998 Positive_regulation of Gene_expression of Calca 31 0.70 16.16 16.98
17 INT77619 Gene_expression of Prkaca 43 0.75 8.55 14.13
18 INT26217 Binding of Calca 22 0.48 5.22 12.57
19 INT78970 Positive_regulation of Positive_regulation of Prkaca 14 0.47 3.06 11.49
20 INT101203 Negative_regulation of Gene_expression of Calca 12 0.59 7.06 10.72
21 INT66382 Positive_regulation of Phosphorylation of Prkaca 33 0.49 7.05 9.69
22 INT40609 Binding of Prkaca 23 0.36 3.42 9.19
23 INT103251 Negative_regulation of Localization of Calca 13 0.43 9.36 8.86
24 INT71478 Positive_regulation of Positive_regulation of Prkaca 21 0.37 5.14 8.85
25 INT142526 Positive_regulation of Gene_expression of Prkaca 12 0.46 2.48 8.05
26 INT124264 Regulation of Localization of Calca 10 0.33 1.39 7.14
27 INT89052 Positive_regulation of Phosphorylation of Prkaca 13 0.37 2.92 7.05
28 INT68466 Negative_regulation of Positive_regulation of Prkaca 6 0.57 2.29 6.83
29 INT33781 Binding of Pebp1 11 0.44 1.76 6.61
30 INT1280 Negative_regulation of Pebp1 7 0.28 2.12 6.45
31 INT85777 Regulation of Negative_regulation of Prkaca 7 0.46 1.85 5.76
32 INT86982 Transcription of Calca 9 0.69 2.98 5.74
33 INT71477 Negative_regulation of Positive_regulation of Prkaca 10 0.37 1.69 5.57
34 INT17056 Gene_expression of DLD 37 0.57 13.15 5.47
35 INT71244 Binding of Prkaca 8 0.30 2.64 4.96
36 INT54987 Regulation of Gene_expression of Calca 6 0.62 3.44 4.59
37 INT108354 Negative_regulation of Phosphorylation of Prkaca 18 0.41 6.24 4.37
38 INT120742 Negative_regulation of Gene_expression of Prkaca 6 0.24 3.76 3.86
39 INT116623 Localization of Prkaca 15 0.73 2.89 3.59
40 INT21572 Gene_expression of Pebp1 9 0.71 2.52 3.3
41 INT78969 Regulation of Positive_regulation of Prkaca 5 0.37 1.38 3.29
42 INT12796 Binding of DLD 20 0.36 6.71 3.02
43 INT57354 Positive_regulation of Positive_regulation of Calca 3 0.60 1.42 2.78
44 INT7142 Positive_regulation of DLD 22 0.60 7.69 2.76
45 INT53447 Negative_regulation of DLD 17 0.54 12.9 2.48
46 INT93341 Localization of Prkaca 7 0.59 2.04 2.28
47 INT103179 Regulation of Phosphorylation of Prkaca 6 0.45 0.79 2.15
48 INT54986 Negative_regulation of Positive_regulation of Calca 2 0.43 0.93 2.02
49 INT169874 Positive_regulation of Gene_expression of Prkaca 11 0.38 1.64 2.01
50 INT13707 Positive_regulation of Pebp1 3 0.41 0.24 1.88
51 INT186427 Negative_regulation of Negative_regulation of Prkaca 2 0.11 0.48 1.73
52 INT1347 Localization of Pebp1 2 0.48 0.17 1.69
53 INT241566 Negative_regulation of Negative_regulation of Calca 1 0.03 0.72 1.63
54 INT108352 Regulation of Phosphorylation of Prkaca 8 0.59 0.68 1.53
55 INT13705 Regulation of Pebp1 2 0.26 0.85 1.3
56 INT155346 Negative_regulation of Negative_regulation of Prkaca 4 0.21 1.34 1.23
57 INT220732 Protein_catabolism of Prkaca 3 0.11 0.61 1.02
58 INT240463 Negative_regulation of Phosphorylation of Prkaca 2 0.23 0.59 0.99
59 INT61613 Regulation of DLD 6 0.34 2.96 0.92
60 INT54985 Positive_regulation of Regulation of Calca 2 0.47 0.33 0.86
61 INT97673 Protein_catabolism of Calca 1 0.50 0.15 0.82
62 INT48909 Localization of DLD 9 0.63 3.37 0.75
63 INT135102 Positive_regulation of Localization of Prkaca 3 0.17 1.21 0.75
64 INT93340 Negative_regulation of Localization of Prkaca 1 0.10 0 0.68
65 INT353152 Localization of PRKACA 1 0.01 1.15 0.66
66 INT150753 Negative_regulation of Gene_expression of Prkaca 1 0.41 0.08 0.65
67 INT72911 Positive_regulation of Negative_regulation of Calca 1 0.43 0.07 0.63
68 INT55594 Negative_regulation of Positive_regulation of DLD 1 0.02 0.62 0.53
69 INT164148 Negative_regulation of Localization of Prkaca 4 0.28 0.28 0.41
70 INT161281 Negative_regulation of Positive_regulation of Pebp1 1 0.07 0 0.41
71 INT71245 Negative_regulation of Binding of Prkaca 2 0.21 0.06 0.4
72 INT18646 Transcription of Pebp1 1 0.50 0.39 0.4
73 INT104989 Positive_regulation of Negative_regulation of Prkaca 2 0.33 0.81 0.37
74 INT242545 Regulation of Regulation of Calca 1 0.15 0 0.36
75 INT66380 Regulation of Negative_regulation of Prkaca 2 0.41 0 0.28
76 INT185926 Regulation of Positive_regulation of Prkaca 5 0.26 0.27 0.25
77 INT59964 Localization of Pcsk4 3 0.59 2.25 0.23
78 INT48785 Gene_expression of PRKACA 1 0.35 0 0.23
79 INT272697 Transcription of Prkaca 2 0.06 0.32 0.22
80 INT136870 Negative_regulation of Pebp1 1 0.33 0.1 0.19
81 INT136867 Localization of Pebp1 1 0.57 0.06 0.19
82 INT139482 Regulation of Gene_expression of Prkaca 3 0.56 0.2 0.18
83 INT128120 Transcription of DLD 1 0.67 0 0.18
84 INT43708 Negative_regulation of Binding of DLD 1 0.35 0.17 0.17
85 INT275321 Negative_regulation of Transcription of Prkaca 1 0.02 0.32 0.15
86 INT136864 Gene_expression of Pebp1 3 0.59 0.43 0.14
87 INT50051 Regulation of Pcsk4 2 0.24 1.07 0.13
88 INT145052 Regulation of Pebp1 1 0.23 0.23 0.13
89 INT173980 Positive_regulation of Gene_expression of Pebp1 1 0.17 0 0.12
90 INT68801 Regulation of Gene_expression of Pebp1 1 0.41 0 0.12
91 INT83129 Protein_catabolism of DLD 1 0.02 0 0.12
92 INT89806 Transcription of Prkaca 2 0.29 0.07 0.09
93 INT137756 Regulation of Negative_regulation of DLD 1 0.02 0.09 0.09
94 INT244341 Regulation of Binding of DLD 1 0.30 0.19 0.06
95 INT136874 Positive_regulation of Pebp1 2 0.38 0.19 0.05
96 INT89802 Positive_regulation of Transcription of Prkaca 1 0.21 0.07 0.05
97 INT287842 Negative_regulation of Regulation of Prkaca 1 0.11 0 0.04
98 INT275364 Positive_regulation of Localization of Prkaca 1 0.28 0.72 0.03
99 INT59962 Gene_expression of Pcsk4 2 0.49 3 0
100 INT114739 Positive_regulation of Negative_regulation of Prkaca 2 0.41 2.03 0
101 INT187586 Regulation of Gene_expression of Pebp1 1 0.03 0.2 0
102 INT149110 Regulation of Negative_regulation of Calca 1 0.18 0.08 0
103 INT217416 Positive_regulation of Positive_regulation of DLD 1 0.42 0.19 0
104 INT108353 Positive_regulation of Regulation of Prkaca 1 0.45 0.08 0
105 INT221520 Negative_regulation of Gene_expression of DLD 1 0.04 0.27 0
106 INT276018 Regulation of Gene_expression of Prkaca 1 0.25 0 0
107 INT350901 Positive_regulation of Pcsk4 1 0.08 1.59 0
108 INT59963 Transcription of Pcsk4 1 0.39 0 0
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