GO:0048265

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Name response to pain
Categary Process
Go Slim No
Go Link GO:0048265
Unique Molecular Interactions 1901
Total Molecular Interactions 2894
Total Single Events 37762
Pain Genes Associated 39

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to pain. They are ordered first by their pain relevance and then by number of times they were reported for response to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT324068 Binding of GCH1 and SNRNP70 1 0.01 28.19 40.6
2 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
3 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36
4 INT166591 Binding of CALCA and DCLK3 4 0.30 0.69 12.18
5 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25
6 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
7 INT26824 Crh Positive_regulation of Localization of Penk 7 0.54 0.42 6.49
8 INT251170 Clu Positive_regulation of Trpv1 1 0.28 2.61 6.49
9 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 8 0.74 4.31 6.1
10 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
11 INT296275 Binding of Dlg4 and Kcnip3 1 0.39 3.58 5.6
12 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27
13 INT15842 Crh Positive_regulation of Localization of Pomc 15 0.73 5 5.05
14 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
15 INT102122 Binding of Calca and RT1-M4 7 0.29 5.83 4.94
16 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
17 INT29206 Crh Regulation of Localization of POMC 4 0.64 0.96 4.68
18 INT24742 Binding of Calca and Vip 1 0.37 0.18 4.68
19 INT351352 Binding of Trpv1 and Lpar1 1 0.21 5.86 4.62
20 INT180774 Gdnf Positive_regulation of Trpv1 1 0.33 2.43 4.37
21 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15
22 INT13969 Binding of Calca and Sst 3 0.32 0.6 4.02
23 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91
24 INT130625 Prkcg Regulation of Prkaca 1 0.23 1.32 3.87
25 INT122349 Ngf Regulation of Trpv1 3 0.64 1.55 3.79
26 INT136525 Binding of Prokr1 and Trpv1 1 0.39 2.9 3.76
27 INT141254 Ngf Regulation of Transcription of Trpv1 1 0.53 1.37 3.74
28 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
29 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63
30 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
31 INT158770 Binding of Trpv1 and Trpa1 5 0.34 2.07 3.5
32 INT24710 Binding of Calca and SUB1P1 1 0.01 2.09 3.48
33 INT195931 Binding of OPRM1 and Trpv1 1 0.07 0.87 3.43
34 INT276676 Prkcg Regulation of Nav1 1 0.30 0.82 3.29
35 INT108471 Binding of CALCA and PNOC 1 0.29 0.64 3.25
36 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
37 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
38 INT18793 Crh Regulation of Localization of Penk 1 0.59 0 3.2
39 INT34294 Penk Positive_regulation of Localization of Crh 1 0.16 0.43 3.19
40 INT29657 Binding of Calca and Calcb 1 0.26 0 3.16
41 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11
42 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 0.41 0.62 3.11
43 INT276679 Prkcg Positive_regulation of Positive_regulation of Nkx1-1 1 0.07 0.94 3.08
44 INT122776 Gdnf Positive_regulation of Gene_expression of Trpv1 2 0.67 2.13 3.06
45 INT106338 Positive_regulation of Tacr1 Positive_regulation of Localization of Abat 5 0.34 0 3.01
46 INT37162 Binding of Calca and Cckar 1 0.04 0.55 3.01
47 INT113234 Binding of Pax3 and Tacr1 3 0.12 1.54 2.93
48 INT100835 Binding of Calca and Akap12 1 0.07 0.41 2.92
49 INT166592 Binding of CALCA and RAMP1 2 0.35 0.33 2.91
50 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
51 INT194409 Binding of CALCA and IGKV1D-8 1 0.15 0 2.84
52 INT351349 Prkcg Positive_regulation of Binding of Lpar1 1 0.15 2 2.82
53 INT169134 Binding of Calca and Trpa1 1 0.37 3.37 2.79
54 INT31513 Crh Regulation of POMC 3 0.29 5.06 2.78
55 INT140347 Binding of ATP1A2 and Cacna1a 1 0.11 2.88 2.73
56 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
57 INT220061 Binding of TRPV1 and TRPA1 1 0.15 1.7 2.69
58 INT182564 Binding of Ptger2 and Trpv1 1 0.18 1.77 2.67
59 INT62450 Il2 Positive_regulation of Localization of Crh 1 0.43 0.59 2.64
60 INT53648 Acot1 Positive_regulation of Localization of Calca 2 0.23 0 2.61
61 INT121742 Prkcg Positive_regulation of Ephb1 3 0.49 0.99 2.6
62 INT29446 Crh Positive_regulation of Localization of POMC 8 0.38 1.87 2.58
63 INT210696 Trpv1 Regulation of Slc12a2 1 0.25 1.97 2.58
64 INT57624 Calca Regulation of Positive_regulation of Trh 1 0.50 0 2.53
65 INT48526 Binding of Calca and Penk 1 0.24 1.03 2.51
66 INT327940 Crh Positive_regulation of Gene_expression of F2rl1 1 0.44 5.57 2.5
67 INT21520 Crh Regulation of Pomc 3 0.22 0.4 2.45
68 INT122775 Gdnf Regulation of Gene_expression of Trpv1 4 0.59 2.72 2.42
69 INT136129 Calca Positive_regulation of ATP8A2 1 0.38 0.89 2.4
70 INT74840 Binding of Cacna1a and Cacna1a 5 0.00 4.24 2.36
71 INT29716 Crh Negative_regulation of Localization of Gnrh1 5 0.44 0 2.35
72 INT107165 Binding of Gabrg1 and Trpv1 2 0.01 0.16 2.34
73 INT13967 Calca Positive_regulation of Sst 1 0.45 0 2.3
74 INT152900 TRPV1 Regulation of Gene_expression of CALCA 1 0.69 0.73 2.29
75 INT152901 TRPV1 Regulation of Localization of CALCA 1 0.44 0.73 2.29
76 INT321474 Binding of Slc6a2 and Ubqln1 1 0.00 0.8 2.27
77 INT228454 Ngf Positive_regulation of Phosphorylation of Trpv1 1 0.39 2.97 2.26
78 INT96652 F2rl1 Positive_regulation of Tac1 1 0.47 2.62 2.25
79 INT251164 Binding of Clu and Trpv1 1 0.19 0.44 2.23
80 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
81 INT140659 Phax Positive_regulation of Trpv1 3 0.49 0.68 2.18
82 INT18791 Crh Regulation of Penk 2 0.49 0 2.15
83 INT135035 Binding of Hk1 and Tac1 1 0.35 0.18 2.14
84 INT79470 Mgat4a Regulation of Localization of Calca 1 0.08 1.72 2.1
85 INT89733 Binding of Calca and Nrm 1 0.31 0.71 2.09
86 INT296277 Binding of Car2 and Kcnip3 5 0.18 1.09 2.06
87 INT30954 Crh Negative_regulation of LH 5 0.46 1.4 2.06
88 INT167530 Phax Regulation of Gene_expression of Trpv1 1 0.16 0.86 2.05
89 INT63873 SRPX Positive_regulation of Localization of Calca 1 0.02 0.49 2.04
90 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
91 INT26221 Calca Regulation of Gt(pU21)50Imeg 1 0.01 0 2.02
92 INT117821 Binding of Tacr1 and Cd4 1 0.34 0.86 2.02
93 INT144115 Positive_regulation of Grm5 Positive_regulation of Prkcg 1 0.41 0 2.01
94 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
95 INT213968 Binding of Calca and Mthfd1 1 0.05 0.16 1.99
96 INT163266 Crh Negative_regulation of Tyr 1 0.01 0.45 1.98
97 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
98 INT262558 Phax Positive_regulation of Trpv1 1 0.01 1.26 1.92
99 INT93293 Ngf Regulation of Trpv1 2 0.28 0.71 1.9
100 INT186435 Prkcg Regulation of Creb1 1 0.44 0.45 1.9
101 INT161079 Mcs18 Negative_regulation of Trpv1 1 0.40 0.82 1.9
102 INT24942 Calca Regulation of TAC1 1 0.13 0.7 1.89
103 INT166945 Ngf Positive_regulation of Trpv1 1 0.01 0.47 1.88
104 INT338691 Binding of Trpv1 and Aff3 1 0.24 1.21 1.88
105 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
106 INT355251 Cacna1a Regulation of Gene_expression of Gabrg1 1 0.01 0.06 1.86
107 INT355249 Cacna1a Regulation of Gene_expression of Ltp 1 0.04 0.06 1.86
108 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
109 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82
110 INT276669 Negative_regulation of Prkcg Regulation of Nav1 1 0.21 0.68 1.82
111 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
112 INT29715 Crh Negative_regulation of Localization of LH 5 0.43 0 1.78
113 INT115048 Kcnip3 Regulation of Gene_expression of Pdyn 2 0.27 0.71 1.78
114 INT23392 Gal Regulation of Trpv1 1 0.05 0.33 1.77
115 INT276863 Gpr65 Regulation of Trpv1 1 0.25 1.78 1.75
116 INT24934 Calca Regulation of Nka1 3 0.05 0.43 1.73
117 INT182565 Ptger2 Regulation of Trpv1 1 0.25 1.34 1.73
118 INT68709 Positive_regulation of Crh Regulation of Npr1 1 0.03 0 1.71
119 INT148090 Binding of CALCA and NCOR2 1 0.00 0.65 1.71
120 INT134363 Prkcg Regulation of ADCY2 1 0.00 0.14 1.7
121 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7
122 INT68710 Crh Regulation of Npr1 1 0.03 0 1.7
123 INT341372 CRX Positive_regulation of Gene_expression of Crh 1 0.04 1.81 1.7
124 INT56134 CALCA Positive_regulation of POMC 2 0.71 0.72 1.68
125 INT102447 Binding of CALCA and CALCRL 2 0.26 0.33 1.67
126 INT324067 Regulation of Binding of GCH1 and SNRNP70 1 0.01 0.95 1.67
127 INT276672 Binding of Prkcg and Nav1 1 0.16 0.18 1.67
128 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
129 INT276680 Binding of Prkcg and Nkx1-1 1 0.05 0.18 1.66
130 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66
131 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
132 INT236491 GCH1 Regulation of Pain1 1 0.01 0.89 1.65
133 INT144213 Nppa Positive_regulation of Localization of Calca 1 0.71 2.8 1.65
134 INT23889 Calca Positive_regulation of Localization of Tacr1 1 0.11 0.45 1.65
135 INT24157 Binding of CALCA and SFTPA1 2 0.07 0.96 1.64
136 INT169441 TAC1 Positive_regulation of Tac1 1 0.01 1.7 1.64
137 INT147258 Binding of Tac1 and Penk 1 0.35 0 1.64
138 INT122286 Prkaca Negative_regulation of Negative_regulation of Calca 1 0.12 0.54 1.63
139 INT160578 Binding of CALCA and TAC1 1 0.07 0.91 1.61
140 INT94270 Pomc Regulation of Transcription of Crh 1 0.17 0.67 1.6
141 INT276670 Binding of Trpv1 and Nkx1-1 1 0.07 0.68 1.6
142 INT151020 Binding of Pdyn and Crh 1 0.14 0.42 1.59
143 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
144 INT355254 Ltp Regulation of Cacna1a 1 0.04 0 1.58
145 INT148935 Ramp1 Regulation of Calca 1 0.27 0.69 1.56
146 INT208980 Binding of Ca2 and Trpv1 4 0.32 0.67 1.55
147 INT74843 Binding of Cacna1a and Ea2 3 0.13 3.29 1.55
148 INT276671 Prkcg Positive_regulation of Nav1 1 0.23 0.21 1.55
149 INT13968 Calca Negative_regulation of Positive_regulation of Sst 1 0.34 0 1.55
150 INT73016 PDYN Regulation of TAC1 1 0.29 0.34 1.54
151 INT284785 Gch1 Regulation of Bh4p 1 0.00 1.48 1.54
152 INT209087 Crh Positive_regulation of Ceacam3 1 0.24 1.45 1.54
153 INT13970 Positive_regulation of Calca Positive_regulation of Sst 1 0.37 0 1.53
154 INT13965 Calca Positive_regulation of Positive_regulation of Sst 1 0.37 0 1.53
155 INT121747 Prkcg Negative_regulation of Positive_regulation of Creb1 1 0.16 0.2 1.5
156 INT42000 Trpv1 Positive_regulation of Cck 1 0.04 0 1.49
157 INT41999 Trpv1 Positive_regulation of Vip 1 0.04 0 1.49
158 INT96784 Binding of CALCA and Calca 3 0.23 0.27 1.47
159 INT59547 Avp Positive_regulation of Crh 2 0.14 1.13 1.47
160 INT161870 OPRM1 Positive_regulation of Prkcg 1 0.01 0.12 1.47
161 INT161865 Mors1 Positive_regulation of Prkcg 1 0.00 0.12 1.47
162 INT180791 Negative_regulation of Gdnf Regulation of Calca 1 0.17 0 1.47
163 INT180767 Bdnf Positive_regulation of Gene_expression of Calca 1 0.17 0 1.45
164 INT276681 Calca Regulation of Nav1 1 0.07 0.74 1.45
165 INT276686 Calca Regulation of Nav1 1 0.26 0.74 1.45
166 INT121226 Ngf Regulation of Gene_expression of Trpv1 2 0.62 0.7 1.44
167 INT153581 Binding of Oprm1 and Prkcg 1 0.00 0 1.44
168 INT180789 Ngf Regulation of Localization of Trpv1 1 0.28 1.22 1.44
169 INT84434 Calca Negative_regulation of Negative_regulation of Hrh1 1 0.06 0.19 1.44
170 INT95325 HTR1B Negative_regulation of Calca 1 0.47 0.69 1.43
171 INT180768 Bdnf Regulation of Localization of Trpv1 1 0.13 1.21 1.43
172 INT180790 Gdnf Regulation of Localization of Trpv1 1 0.15 1.21 1.43
173 INT172203 Binding of Comt and Maoa 1 0.31 0.98 1.43
174 INT202910 Uchl1 Positive_regulation of Gene_expression of Tacr1 1 0.05 1.65 1.42
175 INT134760 Ghrl Regulation of Transcription of Calca 1 0.24 2.71 1.42
176 INT329451 Binding of Oprd1 and Tacr1 1 0.05 0.23 1.41
177 INT128913 Binding of COMT and PENK 1 0.30 0.07 1.41
178 INT78974 Binding of Prkcg and Prkaca 2 0.31 0.35 1.4
179 INT144122 Binding of Calca and P2rx6 1 0.10 0 1.4
180 INT169163 Binding of Calca and Ctbs 1 0.00 0.51 1.4
181 INT199494 Crh Positive_regulation of Localization of Pdyn 1 0.02 0.43 1.4
182 INT154685 Syt17 Positive_regulation of Trpa1 1 0.32 0.71 1.4
183 INT71543 IFNA1 Negative_regulation of Positive_regulation of TAC1 1 0.20 0.19 1.4
184 INT144123 Binding of P2rx6 and Trpv1 1 0.11 0 1.4
185 INT329452 Binding of Tac1 and Oprd1 1 0.01 0.23 1.4
186 INT51213 Vip Regulation of Localization of Calca 1 0.38 0 1.39
187 INT128914 COMT Regulation of OPRM1 1 0.39 0.07 1.39
188 INT8719 Npy Negative_regulation of Localization of Calca 1 0.06 0.26 1.39
189 INT355250 Ltp Regulation of Positive_regulation of Cacna1a 1 0.04 0 1.39
190 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38
191 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38
192 INT51160 Binding of TAC1 and Tacr1 2 0.28 0.55 1.38
193 INT167529 Ppt1 Negative_regulation of Gene_expression of Trpv1 1 0.26 0.49 1.38
194 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
195 INT182558 Binding of Ptgir and Trpv1 1 0.16 1.12 1.37
196 INT276673 Nkx1-1 Regulation of Trpv1 1 0.05 0.16 1.37
197 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
198 INT261483 Binding of Ephb1 and Trpv1 1 0.39 1.37 1.37
199 INT279165 Calca Regulation of Gene_expression of Fdft1 1 0.02 0.41 1.37
200 INT180810 Gopc Positive_regulation of Calca 1 0.02 0.28 1.36

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to pain. They are ordered first by their pain relevance and then by number of times they were reported in response to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 2008 0.81 518.3 1408.65
2 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84
3 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59
4 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08
5 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04
6 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42
7 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42
8 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38
9 INT2649 Regulation of Calca 433 0.62 146.05 330.95
10 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41
11 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59
12 INT1562 Localization of Crh 499 0.81 126.74 236.68
13 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45
14 INT626 Localization of CALCA 289 0.81 125.39 221.15
15 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92
16 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47
17 INT438 Gene_expression of Crh 376 0.78 159.11 169.17
18 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57
19 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2
20 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47
21 INT2541 Binding of Calca 200 0.48 67.14 134.62
22 INT60126 Regulation of Trpv1 186 0.62 85.53 133.4
23 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14
24 INT5008 Localization of Calca 204 0.81 80.35 125.16
25 INT4824 Positive_regulation of Tacr1 169 0.70 66.1 123.46
26 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75
27 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75
28 INT47243 Gene_expression of Prkcg 195 0.78 58.05 108.44
29 INT4936 Localization of Tacr1 125 0.80 35.7 107.7
30 INT4742 Gene_expression of Tac1 177 0.78 69.99 102.66
31 INT1898 Regulation of Crh 220 0.62 61.33 102.64
32 INT89054 Positive_regulation of Gene_expression of Trpv1 156 0.70 90.78 102.03
33 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61
34 INT38731 Localization of Trpv1 138 0.81 52.73 90.49
35 INT12763 Phosphorylation of Prkcg 167 0.82 38.91 89.63
36 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03
37 INT4857 Regulation of Tacr1 115 0.62 39.01 84.52
38 INT4830 Binding of Trpv1 158 0.48 45.11 84.2
39 INT123584 Gene_expression of Trpa1 176 0.78 83 78.65
40 INT25363 Negative_regulation of Trpv1 144 0.59 64.78 75.7
41 INT98621 Regulation of Trpv1 121 0.62 79.24 75.23
42 INT12536 Localization of Prkcg 101 0.80 36.37 73.81
43 INT117601 Positive_regulation of Trpa1 174 0.70 72.41 71.9
44 INT87686 Positive_regulation of Gene_expression of Trpv1 101 0.70 72.41 69.15
45 INT7344 Gene_expression of TAC1 132 0.75 35.48 68.26
46 INT39777 Regulation of Prkcg 90 0.62 31.52 68.17
47 INT96622 Localization of Trpv1 110 0.81 59.82 63.25
48 INT6761 Binding of CALCA 100 0.48 26.71 62.05
49 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3
50 INT109431 Gene_expression of Trpa1 123 0.78 51.84 59.98
51 INT5016 Negative_regulation of Crh 129 0.59 36.74 59.28
52 INT5017 Negative_regulation of Tacr1 76 0.58 17 57.07
53 INT4241 Regulation of CALCA 87 0.62 28.19 55.29
54 INT5509 Positive_regulation of Localization of Crh 91 0.70 30.65 53.92
55 INT4891 Transcription of Calca 81 0.72 35.27 53.75
56 INT8700 Positive_regulation of Positive_regulation of Calca 56 0.67 21.69 53.66
57 INT97674 Positive_regulation of Localization of Calca 70 0.69 27.71 51.79
58 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34
59 INT8690 Localization of Tac1 71 0.80 22.98 50.75
60 INT4985 Positive_regulation of Tac1 81 0.69 35.79 50.67
61 INT109430 Positive_regulation of Trpa1 119 0.70 44 49.14
62 INT66331 Gene_expression of Cacna1a 101 0.78 49.58 46.32
63 INT8713 Regulation of Tac1 56 0.60 25.29 45.94
64 INT4776 Localization of TAC1 82 0.78 16.89 45.21
65 INT14853 Negative_regulation of Tac1 80 0.59 30.87 45.06
66 INT98498 Binding of Trpv1 75 0.48 33.67 44.4
67 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8
68 INT5502 Positive_regulation of Gene_expression of Crh 69 0.70 43.06 42.23
69 INT4850 Binding of Tac1 57 0.47 14.25 42.17
70 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17
71 INT122953 Gene_expression of COMT 65 0.77 25.84 40.49
72 INT26698 Positive_regulation of Cacna1a 37 0.67 26.33 39.1
73 INT4925 Binding of Tacr1 57 0.48 17.39 38.38
74 INT65125 Gene_expression of Tacr1 81 0.77 23.9 38.35
75 INT58062 Negative_regulation of Gene_expression of Trpv1 66 0.59 22.34 38.02
76 INT80075 Regulation of Gene_expression of Trpv1 55 0.62 32.42 36.88
77 INT48959 Positive_regulation of Positive_regulation of Prkcg 52 0.70 16.47 36.49
78 INT8837 Positive_regulation of TAC1 59 0.67 21.94 35.97
79 INT76531 Transcription of Trpv1 62 0.72 23.69 34.77
80 INT4892 Positive_regulation of Gene_expression of Tacr1 56 0.69 25.64 34.69
81 INT12765 Positive_regulation of Phosphorylation of Prkcg 59 0.66 20.16 34.67
82 INT96624 Positive_regulation of Positive_regulation of Trpv1 62 0.70 20.5 34.28
83 INT12537 Positive_regulation of Localization of Prkcg 36 0.70 14.57 33.81
84 INT8784 Negative_regulation of Positive_regulation of Calca 40 0.59 14.67 33.49
85 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45
86 INT51698 Positive_regulation of Gene_expression of Prkcg 44 0.68 14.02 32.9
87 INT4727 Regulation of TAC1 60 0.47 6.74 32.83
88 INT22239 Negative_regulation of TAC1 52 0.57 12.96 31.41
89 INT5507 Regulation of Localization of Crh 57 0.61 8.43 30.26
90 INT9133 Negative_regulation of Positive_regulation of Prkcg 37 0.59 10.95 30.06
91 INT5514 Negative_regulation of Localization of Crh 64 0.58 8.12 29.29
92 INT23463 Positive_regulation of Gene_expression of CALCA 47 0.70 18.14 28.76
93 INT16879 Binding of Crh 72 0.48 21.65 28.43
94 INT149387 Negative_regulation of Trpa1 55 0.59 21.91 28.31
95 INT1166 Negative_regulation of Dbh 56 0.59 12.54 28.26
96 INT22499 Regulation of Calca 42 0.62 17.32 28.02
97 INT21379 Transcription of Crh 65 0.72 15.64 27.92
98 INT8881 Regulation of Gene_expression of Tacr1 38 0.61 17.49 27.19
99 INT127499 Positive_regulation of TRPA1 72 0.70 21.7 26.86
100 INT101120 Gene_expression of Comt 63 0.77 34.75 26.13
101 INT11773 Gene_expression of Tac1 56 0.77 10 25.72
102 INT112036 Phosphorylation of Trpv1 51 0.82 18.59 25.6
103 INT8779 Binding of TAC1 50 0.47 11.19 25.57
104 INT79979 Gene_expression of Ret 94 0.75 19.21 25.51
105 INT103320 Positive_regulation of Positive_regulation of Trpv1 44 0.70 27.73 25.28
106 INT41487 Negative_regulation of Cacna1a 16 0.57 9.42 25.2
107 INT92105 Transcription of Trpv1 47 0.71 27.47 25.01
108 INT127500 Gene_expression of TRPA1 79 0.78 24.58 23.3
109 INT125190 Regulation of Gene_expression of Trpv1 38 0.62 32.57 23.2
110 INT87607 Positive_regulation of Prkcc 25 0.69 6.06 22.78
111 INT89056 Phosphorylation of Trpv1 46 0.82 13.52 22.16
112 INT3382 Positive_regulation of Dbh 33 0.70 11.64 21.67
113 INT8358 Negative_regulation of Localization of CALCA 25 0.59 11.79 21.51
114 INT5503 Negative_regulation of Gene_expression of Crh 38 0.59 16.82 21.34
115 INT110638 Negative_regulation of COMT 43 0.59 21.03 21.05
116 INT440 Regulation of Gene_expression of Crh 44 0.62 17.71 20.73
117 INT519 Negative_regulation of Comt 52 0.59 17.65 20.39
118 INT41494 Negative_regulation of Gene_expression of Tacr1 25 0.58 11.73 19.91
119 INT14436 Gene_expression of Dbh 42 0.72 9.9 19.85
120 INT96511 Negative_regulation of Positive_regulation of Trpv1 35 0.59 10.95 19.79
121 INT135629 Binding of COMT 33 0.48 16.68 19.37
122 INT2960 Regulation of Dbh 32 0.47 10.32 18.94
123 INT90937 Negative_regulation of Gene_expression of Trpv1 34 0.59 22.74 18.12
124 INT12360 Regulation of Tac1 31 0.61 5.9 18
125 INT150934 Gene_expression of GCH1 17 0.78 14.54 17.53
126 INT31136 Binding of Cacna1a 28 0.45 30.76 17.35
127 INT134596 Regulation of Trpa1 32 0.62 18.78 17.02
128 INT35998 Positive_regulation of Gene_expression of Calca 31 0.70 16.16 16.98
129 INT65211 Binding of Prkcg 38 0.48 14.75 16.92
130 INT15202 Regulation of Tacr1 26 0.60 9.65 16.48
131 INT4073 Localization of Dbh 28 0.81 6.06 16.37
132 INT74545 Negative_regulation of Gene_expression of Prkcg 22 0.42 7.77 16.26
133 INT6150 Positive_regulation of Negative_regulation of Calca 20 0.68 4.06 16.26
134 INT9525 Regulation of Positive_regulation of Prkcg 20 0.62 7.82 16.18
135 INT79887 Gene_expression of Prkcc 20 0.78 12.59 14.73
136 INT11980 Positive_regulation of Tac1 27 0.69 6.17 14.5
137 INT63854 Regulation of Gene_expression of Prkcg 27 0.56 9.41 14.15
138 INT51158 Positive_regulation of Tacr1 33 0.70 15.22 13.91
139 INT97848 Positive_regulation of Localization of Trpv1 18 0.50 7.66 13.36
140 INT101119 Negative_regulation of Comt 19 0.58 8.77 13.09
141 INT101494 Regulation of Positive_regulation of Trpv1 18 0.62 6.57 12.9
142 INT65109 Negative_regulation of Transcription of Calca 16 0.59 8.63 12.84
143 INT49041 Transcription of Tacr1 25 0.72 12.52 12.8
144 INT26217 Binding of Calca 22 0.48 5.22 12.57
145 INT30101 Regulation of Cacna1a 25 0.45 14.38 12.43
146 INT120432 Regulation of Trpa1 22 0.61 9.65 12.36
147 INT47847 Negative_regulation of Localization of Prkcg 11 0.58 4.02 12.36
148 INT11244 Transcription of CALCA 21 0.69 3.61 12.27
149 INT17619 Regulation of COMT 12 0.45 8.46 12.22
150 INT520 Binding of Comt 24 0.48 8.98 12.21
151 INT15136 Regulation of Positive_regulation of Calca 12 0.62 3.02 12.16
152 INT145515 Positive_regulation of Localization of Trpv1 23 0.50 10.12 12.08
153 INT6151 Negative_regulation of Negative_regulation of Calca 14 0.58 4.86 11.81
154 INT48691 Negative_regulation of Tacr1 20 0.59 4.96 11.25
155 INT4723 Transcription of Tac1 26 0.71 8.33 11.18
156 INT75765 Positive_regulation of Gene_expression of Cacna1a 17 0.70 17.51 10.91
157 INT5779 Positive_regulation of Transcription of Calca 15 0.62 5.61 10.86
158 INT8589 Positive_regulation of Positive_regulation of Tacr1 14 0.69 7.85 10.86
159 INT23519 Positive_regulation of Localization of Tacr1 12 0.41 3.84 10.82
160 INT101203 Negative_regulation of Gene_expression of Calca 12 0.59 7.06 10.72
161 INT112037 Negative_regulation of Positive_regulation of Trpv1 19 0.59 8.9 10.55
162 INT48806 Negative_regulation of Binding of Tac1 11 0.56 0.83 10.52
163 INT18088 Binding of Tspo 26 0.48 9.12 10.2
164 INT139443 Positive_regulation of GCH1 9 0.69 8.2 10.14
165 INT79248 Regulation of Negative_regulation of Prkcg 13 0.44 3.44 9.78
166 INT134597 Binding of Trpa1 21 0.48 9.41 9.74
167 INT55014 Positive_regulation of Ednrb 31 0.70 16.61 9.68
168 INT183000 Transcription of KCNIP3 4 0.62 12.89 9.59
169 INT47845 Regulation of Localization of Prkcg 16 0.62 3.1 9.42
170 INT89053 Positive_regulation of Phosphorylation of Trpv1 16 0.70 8.89 9.39
171 INT71565 Negative_regulation of Prkcc 11 0.54 4.16 9.31
172 INT144736 Negative_regulation of Gene_expression of COMT 13 0.58 6.47 9.28
173 INT64849 Gene_expression of Ret 24 0.75 14.36 9.1
174 INT122952 Positive_regulation of COMT 13 0.50 8.1 8.89
175 INT103251 Negative_regulation of Localization of Calca 13 0.43 9.36 8.86
176 INT12358 Regulation of Gene_expression of Tac1 17 0.60 3.34 8.84
177 INT146346 Negative_regulation of Gene_expression of Trpa1 15 0.59 11.76 8.83
178 INT182995 Gene_expression of KCNIP3 19 0.69 13.28 8.81
179 INT23331 Positive_regulation of Localization of Tac1 10 0.54 4.63 8.76
180 INT146241 Positive_regulation of Gene_expression of Trpa1 23 0.69 8.07 8.74
181 INT4984 Positive_regulation of Positive_regulation of Tac1 11 0.50 5.34 8.73
182 INT76814 Positive_regulation of Gene_expression of Tacr1 13 0.69 6.11 8.42
183 INT8761 Negative_regulation of Binding of Calca 12 0.43 3.59 8.32
184 INT4940 Negative_regulation of Localization of Tacr1 8 0.37 4.29 8.25
185 INT22700 Positive_regulation of Gene_expression of Tac1 13 0.69 6.89 8.2
186 INT130502 Negative_regulation of Trpa1 17 0.59 5.75 8.06
187 INT48877 Binding of Tacr1 16 0.43 5.26 8.04
188 INT5401 Gene_expression of DBH 17 0.78 1.92 8.01
189 INT5498 Positive_regulation of Positive_regulation of Crh 19 0.70 9.82 7.97
190 INT47546 Binding of Dbh 11 0.44 5.69 7.84
191 INT44537 Positive_regulation of Comt 7 0.69 2.62 7.78
192 INT51206 Regulation of Gene_expression of Tac1 13 0.45 5.92 7.74
193 INT182976 Negative_regulation of KCNIP3 2 0.51 8.49 7.67
194 INT14548 Localization of Tac1 13 0.78 1.43 7.48
195 INT152347 Binding of GCH1 8 0.37 6.13 7.36
196 INT25220 Positive_regulation of Binding of Calca 7 0.69 3.78 7.34
197 INT134379 Binding of Trpa1 13 0.48 7.16 7.27
198 INT101121 Regulation of Comt 19 0.53 10.66 7.22
199 INT124264 Regulation of Localization of Calca 10 0.33 1.39 7.14
200 INT79247 Negative_regulation of Negative_regulation of Prkcg 11 0.42 1.78 7.13
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