GO:0048294

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Name negative regulation of isotype switching to IgE isotypes
Categary Process
Go Slim No
Go Link GO:0048294
Unique Molecular Interactions 25
Total Molecular Interactions 29
Total Single Events 341
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of isotype switching to IgE isotypes. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of isotype switching to IgE isotypes. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT292634 IL4 Positive_regulation of Gene_expression of FOXP3 1 0.10 0.42 0.43
2 INT286965 Binding of STAT3 and FOXP3 1 0.27 1.84 0.19
3 INT296081 Binding of FOXP3 and Gtf3a 1 0.00 1.16 0.16
4 INT296030 Binding of NFKB1 and FOXP3 1 0.17 1.18 0.16
5 INT296082 Binding of Rel and FOXP3 1 0.35 1.14 0.15
6 INT286969 IL2 Regulation of Gene_expression of FOXP3 1 0.04 1.05 0.1
7 INT350700 Binding of Bcl6 and thd 1 0.00 0.21 0.08
8 INT296039 Binding of FOXP3 and IL17RB 1 0.01 0.63 0.08
9 INT296034 FOXP3 Negative_regulation of Gene_expression of IL7R 1 0.10 0.63 0.08
10 INT350692 Binding of Bcl6 and Hand1 1 0.02 0.16 0.08
11 INT350720 Binding of Bcl6 and TBX21 1 0.07 0.22 0.08
12 INT350708 Foxp3 Regulation of Socs1 1 0.08 0.21 0.07
13 INT286967 Positive_regulation of STAT3 Regulation of Gene_expression of FOXP3 1 0.35 0.44 0.04
14 INT350704 Foxp3 Negative_regulation of Gene_expression of Mir142 1 0.02 0.13 0.04
15 INT350696 Mir31 Regulation of Gene_expression of Foxp3 1 0.04 0 0.03
16 INT350707 Uts2r Negative_regulation of Gene_expression of Foxp3 1 0.03 0 0
17 INT256385 Foxp3 Positive_regulation of Cd4 1 0.32 0.15 0
18 INT207266 INS Negative_regulation of BCL6 1 0.29 0.08 0
19 INT322470 Binding of Bcl6 and Hif1a 1 0.06 0.52 0
20 INT305632 Binding of BCL6 and MME 1 0.00 1.37 0
21 INT268508 MIR221 Positive_regulation of BCL6 1 0.03 1.36 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of isotype switching to IgE isotypes. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of isotype switching to IgE isotypes. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT155944 Gene_expression of Foxp3 66 0.66 24.37 9.12
2 INT169015 Gene_expression of FOXP3 50 0.60 33.18 8.4
3 INT188344 Positive_regulation of Gene_expression of Foxp3 10 0.36 5.97 2.56
4 INT221431 Negative_regulation of FOXP3 8 0.40 9.92 1.98
5 INT126457 Gene_expression of BCL6 34 0.66 22.45 1.75
6 INT221426 Positive_regulation of Gene_expression of FOXP3 9 0.48 5.98 1.72
7 INT167872 Negative_regulation of Gene_expression of Foxp3 8 0.50 4.14 1.46
8 INT229562 Negative_regulation of Foxp3 6 0.36 3.7 1.14
9 INT221427 Positive_regulation of FOXP3 6 0.45 2.74 0.83
10 INT157492 Transcription of Foxp3 4 0.61 1.69 0.81
11 INT150251 Transcription of FOXP3 7 0.61 0.43 0.76
12 INT221428 Negative_regulation of Negative_regulation of FOXP3 1 0.35 1.97 0.7
13 INT297286 Positive_regulation of Foxp3 7 0.58 3.05 0.63
14 INT236711 Gene_expression of Bcl6 15 0.30 12.98 0.58
15 INT157490 Regulation of Gene_expression of Foxp3 5 0.37 2.4 0.47
16 INT188345 Regulation of Foxp3 3 0.18 1.59 0.42
17 INT207299 Binding of BCL6 6 0.30 3.5 0.41
18 INT260115 Regulation of FOXP3 3 0.29 0.75 0.34
19 INT121388 Positive_regulation of BCL6 2 0.28 2.71 0.32
20 INT260120 Regulation of Gene_expression of FOXP3 4 0.31 2.74 0.29
21 INT235466 Localization of BCL6 3 0.27 5 0.29
22 INT144881 Positive_regulation of Gene_expression of BCL6 5 0.43 1.6 0.18
23 INT188346 Binding of Foxp3 1 0.27 0.4 0.18
24 INT276372 Negative_regulation of Gene_expression of FOXP3 2 0.38 1.49 0.16
25 INT150253 Positive_regulation of Transcription of FOXP3 2 0.39 0 0.15
26 INT335788 Localization of FOXP3 1 0.34 0.42 0.15
27 INT236693 Positive_regulation of Gene_expression of Bcl6 3 0.15 2.06 0.14
28 INT258953 Negative_regulation of Gene_expression of Bcl6 1 0.19 1.53 0.14
29 INT335812 Regulation of Transcription of FOXP3 1 0.21 0.34 0.14
30 INT286970 Binding of FOXP3 1 0.24 1.04 0.13
31 INT276923 Localization of Foxp3 1 0.38 0.52 0.12
32 INT258955 Localization of Bcl6 1 0.23 0.83 0.11
33 INT286971 Positive_regulation of Positive_regulation of FOXP3 1 0.32 0.57 0.09
34 INT350635 Transcription of Bcl6 1 0.09 0.16 0.08
35 INT350649 Negative_regulation of Transcription of Bcl6 1 0.06 0.16 0.08
36 INT296074 Regulation of Positive_regulation of FOXP3 1 0.18 0.28 0.06
37 INT260113 Positive_regulation of Regulation of FOXP3 1 0.32 0.15 0.04
38 INT207276 Transcription of BCL6 3 0.45 0.64 0.03
39 INT333755 Negative_regulation of Positive_regulation of Foxp3 1 0.49 0.18 0.03
40 INT144882 Negative_regulation of Gene_expression of BCL6 2 0.26 0.93 0
41 INT322454 Positive_regulation of Bcl6 2 0.10 1.6 0
42 INT157493 Positive_regulation of Transcription of Foxp3 1 0.59 0.06 0
43 INT207269 Regulation of BCL6 1 0.38 0.1 0
44 INT277796 Binding of Bcl6 1 0.17 1.33 0
45 INT347438 Regulation of Gene_expression of BCL6 1 0.07 0.7 0
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