GO:0048304

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Name positive regulation of isotype switching to IgG isotypes
Categary Process
Go Slim No
Go Link GO:0048304
Unique Molecular Interactions 885
Total Molecular Interactions 1181
Total Single Events 9025
Pain Genes Associated 18

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of isotype switching to IgG isotypes. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of isotype switching to IgG isotypes. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62
2 INT140935 Binding of Cd40lg and Cd40 1 0.30 6.34 5.61
3 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01
4 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22
5 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12
6 INT62450 Il2 Positive_regulation of Localization of Crh 1 0.43 0.59 2.64
7 INT299783 Binding of Cd28 and Cd80 7 0.14 6.49 2.49
8 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21
9 INT239037 Binding of Cd28 and Cd86 9 0.16 3.69 2.14
10 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
11 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
12 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
13 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
14 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
15 INT92057 Ifng Positive_regulation of Gene_expression of Ik 1 0.03 0.45 1.49
16 INT190772 Il4 Negative_regulation of Gene_expression of Ptger2 1 0.03 1.28 1.49
17 INT21536 Binding of Il2 and Il1 1 0.28 0 1.47
18 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45
19 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45
20 INT83626 Ifng Positive_regulation of Gene_expression of Cd59 1 0.33 2.19 1.41
21 INT190775 Gene_expression of Il4 Negative_regulation of Positive_regulation of FOSL1 1 0.39 2.42 1.4
22 INT160587 IFNG Positive_regulation of Gene_expression of OPRM1 1 0.18 0.54 1.35
23 INT160589 IL4 Positive_regulation of Gene_expression of OPRM1 1 0.13 0.54 1.35
24 INT86172 Pdyn Positive_regulation of Gene_expression of Il2 1 0.20 0 1.33
25 INT62448 Il2 Positive_regulation of Crh 1 0.59 0.36 1.3
26 INT89943 Binding of Oprm1 and Il2 1 0.03 0.53 1.28
27 INT34052 POMC Regulation of Gene_expression of IFNG 1 0.11 0 1.27
28 INT329956 Binding of IL2 and IL23R 1 0.33 4.58 1.21
29 INT142154 Trpv1 Positive_regulation of Gene_expression of Il2 1 0.22 0 1.21
30 INT88193 Binding of IL2 and IL4 1 0.13 1.7 1.2
31 INT142075 IL4 Negative_regulation of Binding of IDO1 1 0.02 2.07 1.19
32 INT190771 Gene_expression of Il4 Negative_regulation of Gene_expression of Mapk14 1 0.15 1.14 1.13
33 INT190770 Il4 Negative_regulation of Gene_expression of Mapk14 1 0.20 1.14 1.13
34 INT122889 Ifng Positive_regulation of Gene_expression of HLA-E 1 0.02 0.97 1.1
35 INT88614 Penk Negative_regulation of Il2 1 0.23 0 1.08
36 INT100678 IL4 Positive_regulation of STAT6 1 0.49 2.63 1.08
37 INT54501 beta-End6-31 Positive_regulation of Gene_expression of Il2 1 0.03 0 1.06
38 INT239038 Negative_regulation of Binding of Cd28 and Cd86 3 0.17 1.5 1.05
39 INT131853 CD40 Negative_regulation of Gene_expression of CD40LG 1 0.09 1.54 1.05
40 INT113235 Tacr1 Regulation of Gene_expression of Ifng 1 0.26 1 1.04
41 INT88875 Ifng Positive_regulation of Transcription of Nos2 1 0.02 0.27 1.03
42 INT174468 IL7 Positive_regulation of Gene_expression of IL4 1 0.40 1.88 1.02
43 INT88874 Ifng Regulation of Nos2 1 0.01 0.26 1.01
44 INT88879 Ifng Positive_regulation of Nfkb1 1 0.01 0.26 1.01
45 INT21415 POMC Positive_regulation of Gene_expression of IL2 1 0.00 0.27 1
46 INT228496 Il4 Negative_regulation of Hand1 1 0.02 1.4 0.99
47 INT103928 Binding of Cd28 and Trav6-3 3 0.03 0.55 0.98
48 INT140934 Binding of Cd40 and Ean5 1 0.09 1.03 0.98
49 INT94493 Avp Positive_regulation of Gene_expression of Ifng 1 0.05 1.73 0.97
50 INT77142 Binding of IFNG and IL4 2 0.03 1.16 0.95
51 INT129214 RYBP Positive_regulation of Gene_expression of Il4 1 0.01 1.04 0.94
52 INT265210 Binding of Ctla4 and Cd28 2 0.16 1.45 0.93
53 INT94501 Il2 Positive_regulation of Gene_expression of Ifng 1 0.03 1.63 0.92
54 INT85879 Il12a Positive_regulation of Gene_expression of Ifng 1 0.20 0.89 0.92
55 INT133073 IL4 Positive_regulation of Phosphorylation of STAT6 1 0.39 0 0.9
56 INT91272 Ifng Positive_regulation of Localization of Il6 1 0.29 0 0.88
57 INT73492 PTGER2 Positive_regulation of Gene_expression of IL4 1 0.08 1.11 0.87
58 INT213977 Pax3 Negative_regulation of Gene_expression of Il2 1 0.00 0.25 0.86
59 INT213976 Calca Negative_regulation of Gene_expression of Il2 1 0.03 0.25 0.86
60 INT161306 POMC Negative_regulation of Transcription of IL2 1 0.24 0.27 0.85
61 INT161307 JUN Positive_regulation of IL2 1 0.14 0.25 0.84
62 INT120999 Binding of Oprm1 and Ifng 1 0.22 0.57 0.84
63 INT174509 Binding of CD4 and CD28 1 0.26 1.68 0.84
64 INT161305 NFKB1 Positive_regulation of IL2 1 0.25 0.25 0.83
65 INT94331 IFNG Positive_regulation of CXCL10 4 0.11 1.31 0.82
66 INT188567 IRF6 Positive_regulation of Gene_expression of CD28 1 0.05 1.28 0.82
67 INT12883 Binding of IL2 and POMC 1 0.01 0 0.81
68 INT53199 Positive_regulation of Cd4 Positive_regulation of Gene_expression of Il2 1 0.52 0.72 0.8
69 INT8411 IL2 Regulation of Gene_expression of Vip 1 0.00 0.27 0.8
70 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79
71 INT199495 Il4 Positive_regulation of Positive_regulation of Oprm1 1 0.00 0.98 0.78
72 INT199476 Il4 Positive_regulation of Transcription of Stat6 1 0.01 0.97 0.77
73 INT209882 IL4 Positive_regulation of Gene_expression of TNFRSF11A 1 0.11 1.82 0.76
74 INT81299 Ifng Positive_regulation of Gene_expression of Hmox1 1 0.52 0.75 0.76
75 INT150995 Sfpq Positive_regulation of Gene_expression of Il4 1 0.06 0.71 0.74
76 INT209035 Il2 Positive_regulation of Ccr1 1 0.00 0.38 0.73
77 INT21535 Binding of Il2 and Il1f5 1 0.13 0 0.73
78 INT209037 Il4 Positive_regulation of Csf2 1 0.03 0.38 0.73
79 INT209038 Il4 Positive_regulation of Ccr1 1 0.01 0.38 0.73
80 INT209058 Il4 Positive_regulation of Elf1 1 0.08 0.38 0.73
81 INT209052 Il2 Positive_regulation of Il17a 1 0.03 0.38 0.73
82 INT209034 Il4 Positive_regulation of Il17a 1 0.04 0.38 0.73
83 INT199488 Il4 Positive_regulation of Transcription of Oprm1 1 0.01 0.84 0.73
84 INT209053 Il2 Positive_regulation of Elf1 1 0.06 0.38 0.73
85 INT209064 Il4 Positive_regulation of Cxcl1 1 0.05 0.38 0.73
86 INT209036 Il2 Positive_regulation of Cxcl1 1 0.04 0.38 0.73
87 INT209051 Il2 Positive_regulation of Csf2 1 0.02 0.38 0.73
88 INT266769 IL2 Positive_regulation of Localization of IL4 1 0.00 1.03 0.72
89 INT266765 IL2 Positive_regulation of Localization of IL10 1 0.01 1.03 0.72
90 INT146460 IFNG Positive_regulation of Gene_expression of TNFRSF10D 1 0.03 1.46 0.72
91 INT151679 Ifng Negative_regulation of Oas1b 1 0.12 1.24 0.71
92 INT146461 IFNG Positive_regulation of NFKB1 1 0.01 1.44 0.71
93 INT151676 Ifng Negative_regulation of Art2a-ps 1 0.00 1.25 0.71
94 INT27034 HERPUD1 Regulation of Gene_expression of IL2 1 0.38 0 0.71
95 INT116020 Positive_regulation of Binding of Il4 and Mavs 1 0.02 0.08 0.7
96 INT116021 Binding of Il4 and Mavs 1 0.02 0.08 0.7
97 INT116019 Negative_regulation of Binding of Il4 and Mavs 1 0.02 0.08 0.7
98 INT151681 Il2 Negative_regulation of Art2a-ps 1 0.00 1.23 0.7
99 INT99818 IFNG Positive_regulation of Gene_expression of APP 1 0.04 0.82 0.7
100 INT151678 Il2 Negative_regulation of Oas1b 1 0.13 1.23 0.7
101 INT172143 IL4 Positive_regulation of Protein_catabolism of TNF 2 0.11 1.7 0.69
102 INT325267 Il33 Positive_regulation of Gene_expression of Il4 1 0.16 1.59 0.69
103 INT209859 IL4 Positive_regulation of PPARA 1 0.22 1.66 0.69
104 INT172132 IL4 Positive_regulation of Protein_catabolism of IL1B 2 0.02 1.69 0.68
105 INT190177 Gene_expression of IL13 Regulation of Gene_expression of IL4 1 0.04 0.05 0.68
106 INT54502 Pomc Positive_regulation of Gene_expression of Il2 1 0.16 0 0.68
107 INT129921 IL4 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.38 0.68
108 INT190171 Gene_expression of IL4 Regulation of Gene_expression of IL13 1 0.04 0.05 0.68
109 INT190164 Gene_expression of IL4 Regulation of MMP12 1 0.11 0.05 0.68
110 INT184120 Il4 Positive_regulation of Stat6 3 0.09 2.39 0.67
111 INT230336 IL4 Regulation of IL5 2 0.04 0.82 0.67
112 INT56308 POMC Negative_regulation of Gene_expression of Il2 1 0.01 0.1 0.67
113 INT231533 IL4 Positive_regulation of LRP5 1 0.00 0.87 0.67
114 INT82382 Penk Positive_regulation of Gene_expression of Il2 1 0.10 0 0.66
115 INT209854 IL4 Positive_regulation of Gene_expression of CD36 1 0.51 1.2 0.65
116 INT103868 IFNG Positive_regulation of Hmox1 1 0.09 0.83 0.65
117 INT72504 IgG Negative_regulation of Il2 1 0.37 0 0.65
118 INT243639 Twist1 Negative_regulation of Gene_expression of Il2 1 0.24 1.28 0.65
119 INT142076 IL4 Negative_regulation of Gene_expression of IFNG 1 0.01 1.58 0.64
120 INT86171 Oprl1 Positive_regulation of Gene_expression of Il2 1 0.30 0 0.64
121 INT172139 IL4 Negative_regulation of IL1B 1 0.02 0.85 0.63
122 INT94075 ARSA Negative_regulation of Gene_expression of IL4 1 0.28 0.26 0.62
123 INT56235 Ifng Positive_regulation of Gene_expression of RT1-EC2 1 0.23 0.33 0.62
124 INT190170 IL4 Regulation of Gene_expression of IL13 1 0.04 0 0.62
125 INT190175 IL13 Regulation of Gene_expression of IL4 1 0.04 0 0.62
126 INT92998 Positive_regulation of SFTPA1 Positive_regulation of Localization of CD40 1 0.15 0.34 0.61
127 INT154530 Positive_regulation of Ifng Negative_regulation of Il10 1 0.33 0.63 0.61
128 INT154533 Ifng Negative_regulation of Il4 1 0.11 0.62 0.6
129 INT190180 IL4 Regulation of MMP12 1 0.11 0 0.6
130 INT154531 Ifng Negative_regulation of Il10 1 0.30 0.61 0.6
131 INT13238 POMC Regulation of Gene_expression of IL2 1 0.09 0.26 0.59
132 INT151460 Olr1745 Positive_regulation of Il4 1 0.04 0.83 0.59
133 INT60375 Il2 Regulation of Localization of Penk 1 0.03 0 0.59
134 INT56451 Ifng Positive_regulation of Tnf 1 0.00 1.92 0.59
135 INT87024 Positive_regulation of ZAK Positive_regulation of Localization of IFNG 2 0.05 0.81 0.58
136 INT74656 YY1 Positive_regulation of Localization of IL2 1 0.07 0.09 0.58
137 INT62034 POMC Regulation of Positive_regulation of IL4 1 0.44 0 0.58
138 INT60374 Il2 Positive_regulation of Pomc 1 0.07 0 0.58
139 INT60372 Il2 Positive_regulation of Localization of Pomc 1 0.08 0 0.58
140 INT60373 Il2 Positive_regulation of Localization of Penk 1 0.52 0 0.58
141 INT172144 IL4 Negative_regulation of Transcription of PLA2G4A 1 0.02 0.82 0.58
142 INT172133 IL4 Negative_regulation of Gene_expression of HMOX2 1 0.00 0.81 0.58
143 INT92999 Binding of CD40 and VCAM1 1 0.39 0.33 0.57
144 INT39210 TF Positive_regulation of Gene_expression of IL2 1 0.17 0.07 0.57
145 INT228497 Il4 Regulation of Ncoa5 1 0.01 1.24 0.57
146 INT184243 Mthfd1 Negative_regulation of Gene_expression of Il4 1 0.02 0.88 0.56
147 INT141362 EP300 Negative_regulation of Transcription of IL2 1 0.17 0 0.56
148 INT144598 Hrh2 Positive_regulation of IL2 1 0.01 0.08 0.56
149 INT190702 CD40 Positive_regulation of Gene_expression of F3 1 0.00 1.4 0.55
150 INT254280 Il4 Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.79 0.54
151 INT137162 IFNG Positive_regulation of Gene_expression of CXCL9 1 0.45 0.62 0.54
152 INT226360 IL18 Positive_regulation of Gene_expression of IL4 1 0.05 2.66 0.54
153 INT88024 Ifng Positive_regulation of Gene_expression of Faslg 2 0.50 1.19 0.53
154 INT351332 Positive_regulation of Il4 Positive_regulation of Gene_expression of Il10 1 0.09 1.78 0.53
155 INT328058 IL4 Positive_regulation of FAAH 1 0.29 4.29 0.53
156 INT249600 IFNA1 Positive_regulation of Gene_expression of Cd40 1 0.49 1.13 0.52
157 INT184088 Epo Positive_regulation of Il2 1 0.07 0.26 0.52
158 INT274170 Il13 Regulation of Il4 3 0.09 2.75 0.51
159 INT138928 Ifng Positive_regulation of Transcription of Cxcl9 1 0.31 0.65 0.51
160 INT254356 Binding of IFNG and IL1B 1 0.00 1.87 0.51
161 INT143504 IFNG Positive_regulation of Gene_expression of Aif1 1 0.04 1.26 0.51
162 INT131371 MAPK3 Positive_regulation of Il4 1 0.02 0.37 0.51
163 INT131364 Bcar3 Positive_regulation of Il4 1 0.00 0.37 0.51
164 INT131370 MAPK3 Positive_regulation of Gene_expression of Il4 1 0.02 0.37 0.51
165 INT103937 Cps1 Negative_regulation of Gene_expression of Cd28 1 0.03 0.19 0.51
166 INT184132 Il2 Positive_regulation of Stat5a 1 0.09 0.26 0.51
167 INT131369 MAPK1 Positive_regulation of Il4 1 0.01 0.37 0.51
168 INT299785 CTLA4 Negative_regulation of Binding of CD28 2 0.17 1.8 0.5
169 INT70925 Binding of Ifng and Il4 2 0.14 0.9 0.5
170 INT349636 IL17A Positive_regulation of Gene_expression of IL4 1 0.06 1.28 0.5
171 INT32597 Pomc Regulation of Gene_expression of Il2 1 0.29 0 0.49
172 INT184099 Il4 Positive_regulation of Stat4 1 0.13 0.28 0.49
173 INT138927 Ifng Positive_regulation of Gene_expression of Stat1 1 0.29 0.7 0.49
174 INT300551 TBX21 Regulation of Hand1 2 0.10 0.44 0.48
175 INT300956 Il4 Negative_regulation of IL8 1 0.02 0.37 0.48
176 INT142155 Ifng Positive_regulation of Il5 1 0.08 0 0.48
177 INT300960 Il4 Negative_regulation of IL1B 1 0.03 0.37 0.48
178 INT300957 Binding of IL13 and Il4 1 0.01 0.58 0.48
179 INT300959 Il4 Negative_regulation of TNF 1 0.03 0.37 0.48
180 INT300955 Il4 Negative_regulation of Il6 1 0.03 0.37 0.48
181 INT185067 Bpifa2 Positive_regulation of Il4 1 0.20 0.84 0.48
182 INT132792 IL4 Positive_regulation of IL6 4 0.28 1.81 0.47
183 INT196634 IFNG Negative_regulation of DNAH8 1 0.03 1.49 0.47
184 INT149121 Binding of CD80 and Cd28 2 0.04 0.95 0.46
185 INT323905 Positive_regulation of CNDP1 Positive_regulation of IL4 1 0.00 0.9 0.46
186 INT296114 Il4 Regulation of Gene_expression of Arg1 1 0.00 0.65 0.46
187 INT323904 CNDP1 Positive_regulation of IL4 1 0.00 0.9 0.46
188 INT72087 IL4 Positive_regulation of POMC 1 0.16 0 0.46
189 INT306732 Il17a Positive_regulation of Gene_expression of Il2 1 0.09 1.07 0.46
190 INT99790 Ifng Positive_regulation of Cxcr2 1 0.12 0.28 0.46
191 INT175788 Il2 Positive_regulation of Localization of Avp 1 0.03 0.41 0.46
192 INT306731 Il22 Positive_regulation of Gene_expression of Il2 1 0.12 1.07 0.46
193 INT323907 ACCS Positive_regulation of IL4 1 0.04 0.9 0.45
194 INT126337 Pax3 Positive_regulation of Gene_expression of Ifng 1 0.05 0.56 0.44
195 INT279360 ADA Negative_regulation of Gene_expression of IFNG 1 0.06 0.51 0.44
196 INT126340 Pax3 Regulation of Gene_expression of Ifng 1 0.03 0.56 0.44
197 INT352972 IL4 Negative_regulation of Gene_expression of IL8 1 0.07 1.01 0.43
198 INT188565 IRF6 Regulation of Gene_expression of CD28 1 0.03 0.7 0.43
199 INT126338 Insrr Regulation of Gene_expression of Ifng 1 0.00 0.56 0.43
200 INT189154 MTNR1B Positive_regulation of Gene_expression of IFNG 1 0.01 0.06 0.43

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of isotype switching to IgG isotypes. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of isotype switching to IgG isotypes. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69
2 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12
3 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57
4 INT48244 Gene_expression of Il4 172 0.76 132.38 73.42
5 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92
6 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14
7 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6
8 INT11807 Gene_expression of Il2 266 0.78 112 64.97
9 INT12345 Gene_expression of Il2 142 0.78 59.17 51.21
10 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67
11 INT10763 Localization of IL2 157 0.80 81.11 33.21
12 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7
13 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4
14 INT54302 Positive_regulation of Gene_expression of Il4 126 0.68 86.18 30.75
15 INT9993 Positive_regulation of Gene_expression of IL2 131 0.69 46.27 30.04
16 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96
17 INT56224 Negative_regulation of Gene_expression of Ifng 40 0.58 23.34 25.08
18 INT43486 Positive_regulation of Ifng 52 0.69 32.71 24.77
19 INT8518 Localization of Ifng 53 0.81 36.68 24.13
20 INT50039 Positive_regulation of Il4 48 0.55 34.8 23.34
21 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05
22 INT96156 Gene_expression of Cd40 144 0.77 56.95 21.7
23 INT11804 Positive_regulation of Gene_expression of Il2 70 0.70 33 21.63
24 INT15796 Regulation of IL2 66 0.61 25.43 20.62
25 INT20379 Localization of Il4 85 0.73 51.22 20.55
26 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39
27 INT25222 Positive_regulation of Gene_expression of Ifng 32 0.50 24.18 19.58
28 INT11803 Positive_regulation of Il2 62 0.70 31.44 18.93
29 INT19509 Localization of Ifng 55 0.78 28.25 18.67
30 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65
31 INT35086 Positive_regulation of Gene_expression of Ifng 40 0.69 22.55 18.35
32 INT80755 Gene_expression of CD40 88 0.75 53.68 17.86
33 INT24209 Negative_regulation of Ifng 37 0.57 16.52 17.15
34 INT21532 Negative_regulation of Gene_expression of Il2 47 0.59 20.43 16.96
35 INT10000 Regulation of Gene_expression of IL2 56 0.45 15.33 16.2
36 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89
37 INT10360 Positive_regulation of Ifng 33 0.68 21.73 15.19
38 INT69303 Positive_regulation of Gene_expression of Il4 27 0.68 20.01 14.8
39 INT22098 Positive_regulation of Il2 27 0.69 14.77 14.1
40 INT133156 Binding of Cd40 77 0.48 45.92 13.77
41 INT4931 Localization of IFNG 53 0.78 33.25 13.65
42 INT171134 Gene_expression of CD28 67 0.65 32.55 13.61
43 INT87235 Negative_regulation of Il4 54 0.48 31.51 13.15
44 INT7532 Negative_regulation of Gene_expression of Ifng 33 0.59 18.56 13.14
45 INT20381 Localization of Il2 71 0.77 34.23 13.03
46 INT51014 Transcription of IL2 42 0.71 21.56 12.7
47 INT32595 Positive_regulation of Gene_expression of Il2 30 0.70 6.55 12.56
48 INT5057 Negative_regulation of Gene_expression of IFNG 23 0.58 8.33 12.3
49 INT69158 Localization of IL4 48 0.71 31.3 11.98
50 INT9160 Negative_regulation of Ifng 31 0.58 16.37 11.84
51 INT55886 Negative_regulation of Gene_expression of Il4 47 0.57 26.04 11.42
52 INT14334 Negative_regulation of Il2 31 0.58 18.63 11.08
53 INT19944 Negative_regulation of IFNG 39 0.58 22.35 10.91
54 INT12344 Negative_regulation of Gene_expression of Il2 28 0.59 15.53 10.23
55 INT73504 Binding of CD28 35 0.45 15.99 10.04
56 INT49884 Negative_regulation of Gene_expression of Il4 18 0.55 14.06 8.9
57 INT79693 Regulation of Il4 30 0.51 21.96 8.6
58 INT22383 Binding of IL2 59 0.48 39.06 8.56
59 INT70303 Negative_regulation of Il4 19 0.52 12.9 8.54
60 INT61628 Negative_regulation of Gene_expression of IL4 31 0.55 20.96 8.18
61 INT32596 Regulation of Gene_expression of Il2 13 0.61 6.85 7.83
62 INT94125 Gene_expression of Cd28 38 0.67 21.73 7.75
63 INT50040 Localization of Il4 15 0.67 8.26 7.69
64 INT62452 Regulation of Il2 14 0.61 12.11 7.64
65 INT51741 Regulation of Gene_expression of Il4 23 0.36 12.7 7.39
66 INT70814 Negative_regulation of Il2 40 0.56 13.36 7.22
67 INT5326 Regulation of Ifng 12 0.55 4.56 7.19
68 INT93003 Binding of CD40 28 0.47 20.25 7.13
69 INT76120 Gene_expression of Ptprc 102 0.59 30.42 7.02
70 INT25385 Positive_regulation of Localization of Il2 17 0.45 9.53 6.45
71 INT74154 Transcription of Ifng 14 0.67 10.33 6.21
72 INT58484 Regulation of Il4 12 0.45 8.67 6.09
73 INT67397 Transcription of Il4 15 0.54 11.36 6.06
74 INT15803 Regulation of IFNG 21 0.44 12.57 5.98
75 INT5186 Regulation of Ifng 11 0.45 8.78 5.9
76 INT12066 Localization of Il2 16 0.75 3.06 5.7
77 INT142607 Positive_regulation of Gene_expression of Cd40 41 0.62 13.85 5.51
78 INT56299 Transcription of IL4 15 0.64 10.2 5.44
79 INT77146 Binding of IL4 23 0.36 13.69 5.39
80 INT171562 Regulation of IL4 19 0.36 12.12 5.33
81 INT11805 Regulation of Gene_expression of Il2 19 0.62 6.62 5.2
82 INT67228 Regulation of Gene_expression of Il4 11 0.50 6.67 5.2
83 INT59320 Transcription of Il2 32 0.69 6.39 4.95
84 INT58459 Negative_regulation of Localization of IL2 13 0.41 6.46 4.88
85 INT62132 Regulation of Gene_expression of Ifng 12 0.62 1.28 4.77
86 INT101594 Positive_regulation of Cd40 36 0.69 16.14 4.56
87 INT116902 Positive_regulation of CD28 17 0.47 13.56 4.27
88 INT56594 Positive_regulation of Localization of Il4 17 0.48 10.17 4.15
89 INT64473 Regulation of Gene_expression of IL4 17 0.58 6.61 3.96
90 INT29138 Positive_regulation of Localization of IL2 25 0.50 10.06 3.89
91 INT62497 Binding of Il4 7 0.26 4.19 3.88
92 INT34054 Regulation of Gene_expression of IFNG 8 0.42 3.69 3.76
93 INT92200 Negative_regulation of Localization of Il4 10 0.51 5.66 3.65
94 INT140932 Binding of Cd40 1 0.44 4.19 3.6
95 INT70919 Binding of Il4 19 0.36 6.58 3.59
96 INT69155 Positive_regulation of Localization of IL4 13 0.40 10.18 3.56
97 INT118615 Negative_regulation of IL4 20 0.41 13.79 3.49
98 INT97438 Transcription of Il4 17 0.67 9.17 3.4
99 INT188355 Binding of Cd28 25 0.34 8.29 3.38
100 INT93915 Positive_regulation of Gene_expression of CD40 14 0.44 12.45 3.35
101 INT87027 Positive_regulation of Localization of IFNG 12 0.67 5.78 3.35
102 INT142606 Regulation of Gene_expression of Cd40 13 0.56 6.15 3.27
103 INT93913 Positive_regulation of CD40 21 0.58 23.47 3.1
104 INT240544 Gene_expression of TBX21 12 0.75 5.96 2.97
105 INT140929 Gene_expression of Cd40 9 0.72 8.76 2.88
106 INT11815 Regulation of Il2 16 0.59 4.81 2.83
107 INT67078 Binding of Ifng 7 0.48 4.84 2.73
108 INT15197 Regulation of Gene_expression of Ifng 8 0.34 2.66 2.69
109 INT174527 Negative_regulation of CD28 13 0.35 5.06 2.65
110 INT22831 Negative_regulation of Positive_regulation of IL2 7 0.55 1.7 2.62
111 INT111145 Negative_regulation of Positive_regulation of Ifng 7 0.41 2.21 2.61
112 INT96151 Negative_regulation of Gene_expression of Cd40 20 0.58 6.06 2.58
113 INT91669 Negative_regulation of Localization of IFNG 5 0.57 4.1 2.58
114 INT187454 Binding of Ptprc 34 0.38 9.66 2.54
115 INT16964 Binding of IFNG 27 0.48 14.31 2.45
116 INT141367 Negative_regulation of Transcription of IL2 9 0.32 2.07 2.43
117 INT73980 Transcription of Ifng 12 0.72 5.42 2.4
118 INT248297 Negative_regulation of Cd40 14 0.58 8.96 2.34
119 INT70918 Positive_regulation of Localization of Ifng 5 0.45 2.79 2.33
120 INT157049 Regulation of Localization of Il4 2 0.25 1.46 2.33
121 INT25382 Binding of Il2 16 0.37 11.69 2.32
122 INT72531 Binding of Il2 2 0.48 0.18 2.32
123 INT67437 Negative_regulation of Localization of Ifng 7 0.47 2.23 2.28
124 INT144652 Negative_regulation of Binding of CD28 6 0.55 3.09 2.28
125 INT20289 Regulation of Localization of IL2 7 0.26 1.23 2.24
126 INT92119 Negative_regulation of Positive_regulation of Il4 3 0.14 1.88 2.2
127 INT112784 Positive_regulation of Positive_regulation of IFNG 11 0.49 7.84 2.18
128 INT140818 Positive_regulation of Positive_regulation of Ifng 2 0.47 4.2 2.06
129 INT111530 Positive_regulation of Regulation of Ifng 1 0.41 0.32 2.01
130 INT11136 Positive_regulation of Localization of Ifng 4 0.49 3.13 1.89
131 INT52789 Regulation of Localization of Il2 9 0.30 1.9 1.88
132 INT174511 Positive_regulation of Gene_expression of CD28 7 0.41 4.31 1.83
133 INT61627 Transcription of IFNG 6 0.69 4.28 1.83
134 INT199591 Protein_catabolism of IL2 2 0.05 1.2 1.81
135 INT97108 Phosphorylation of IL2 5 0.73 2.47 1.7
136 INT76417 Positive_regulation of Positive_regulation of Il4 3 0.09 0.34 1.7
137 INT157050 Regulation of Localization of Il2 1 0.06 0 1.67
138 INT97434 Positive_regulation of Positive_regulation of Il4 8 0.40 3.51 1.66
139 INT174478 Negative_regulation of Localization of IL4 6 0.34 3.56 1.65
140 INT87236 Regulation of Negative_regulation of Il2 3 0.24 0.75 1.62
141 INT206528 Negative_regulation of Gene_expression of Ptprc 8 0.34 3.91 1.61
142 INT113716 Positive_regulation of Transcription of Ifng 1 0.53 2.56 1.61
143 INT88746 Positive_regulation of Transcription of IL2 7 0.51 2.14 1.6
144 INT22329 Gene_expression of Ptprc 36 0.66 15.84 1.59
145 INT100694 Negative_regulation of Positive_regulation of IL4 5 0.34 3.27 1.58
146 INT184241 Regulation of Localization of Il4 4 0.15 3.89 1.58
147 INT118400 Positive_regulation of Transcription of Il4 2 0.35 1.78 1.53
148 INT171133 Localization of CD28 8 0.71 3.42 1.48
149 INT128478 Positive_regulation of Ptprc 26 0.44 8.1 1.45
150 INT93001 Localization of CD40 4 0.78 1.97 1.45
151 INT152190 Positive_regulation of Phosphorylation of IL2 1 0.23 0.2 1.41
152 INT56228 Positive_regulation of Positive_regulation of Ifng 2 0.43 2.83 1.4
153 INT87029 Positive_regulation of Positive_regulation of IL2 8 0.50 8.17 1.36
154 INT94126 Positive_regulation of Cd28 9 0.50 4.23 1.33
155 INT188691 Negative_regulation of Binding of Cd40 3 0.42 2.49 1.31
156 INT90771 Positive_regulation of Ptprc 20 0.48 8.43 1.27
157 INT11137 Negative_regulation of Localization of Ifng 3 0.38 2.45 1.26
158 INT19923 Regulation of Localization of Ifng 3 0.22 1.1 1.25
159 INT72099 Positive_regulation of Positive_regulation of IL4 4 0.43 0.71 1.24
160 INT147976 Regulation of Positive_regulation of Il4 2 0.32 2.25 1.23
161 INT109243 Regulation of Positive_regulation of IFNG 1 0.45 1.27 1.23
162 INT206515 Regulation of Gene_expression of Ptprc 6 0.39 3.4 1.22
163 INT174557 Negative_regulation of Gene_expression of Cd28 7 0.43 4.42 1.2
164 INT236091 Positive_regulation of Transcription of Il2 2 0.44 2.78 1.19
165 INT111536 Positive_regulation of Negative_regulation of Ifng 1 0.41 0.35 1.18
166 INT59319 Negative_regulation of Positive_regulation of Il4 6 0.57 3.48 1.17
167 INT97261 Negative_regulation of Regulation of IL2 2 0.26 1.04 1.17
168 INT189836 Regulation of Cd40 10 0.40 3.02 1.1
169 INT112004 Positive_regulation of Negative_regulation of IL2 3 0.50 1.56 1.08
170 INT174550 Negative_regulation of Cd28 7 0.33 4.7 1.06
171 INT22830 Negative_regulation of Binding of IL2 4 0.55 4.8 1.06
172 INT122884 Positive_regulation of Transcription of Ifng 1 0.39 1.08 1.03
173 INT138543 Negative_regulation of Cd28 3 0.11 2.1 1.01
174 INT140930 Positive_regulation of Gene_expression of Cd40 4 0.64 3.26 0.99
175 INT147464 Binding of Ptprc 13 0.36 15.18 0.98
176 INT85869 Transcription of Il2 5 0.23 2.49 0.95
177 INT240542 Positive_regulation of TBX21 3 0.45 2.11 0.89
178 INT70817 Negative_regulation of Transcription of Il2 5 0.40 0.25 0.87
179 INT120447 Negative_regulation of Localization of Il2 9 0.56 1.74 0.86
180 INT103303 Negative_regulation of Transcription of Ifng 6 0.43 2.7 0.83
181 INT43488 Regulation of Positive_regulation of Ifng 1 0.42 0.71 0.83
182 INT147634 Regulation of Cd28 2 0.44 3.23 0.82
183 INT64635 Binding of Ifng 2 0.36 0.57 0.81
184 INT230516 Negative_regulation of Localization of Il2 5 0.15 2.64 0.79
185 INT19279 Negative_regulation of Negative_regulation of IL2 3 0.43 1.62 0.79
186 INT240543 Negative_regulation of TBX21 1 0.42 2.26 0.79
187 INT170603 Negative_regulation of Gene_expression of CD40 5 0.32 2.18 0.78
188 INT177965 Negative_regulation of Transcription of IL4 3 0.25 2.11 0.78
189 INT11138 Regulation of Localization of Ifng 2 0.56 0.8 0.77
190 INT70815 Negative_regulation of Positive_regulation of Il2 4 0.40 1.37 0.76
191 INT73240 Negative_regulation of Transcription of IFNG 1 0.41 0.92 0.76
192 INT149698 Negative_regulation of Binding of Cd28 2 0.15 1.21 0.75
193 INT149697 Binding of Cd28 2 0.12 1.16 0.74
194 INT91274 Negative_regulation of Positive_regulation of Il2 2 0.42 1.12 0.74
195 INT72096 Regulation of Positive_regulation of IL4 2 0.20 0.51 0.72
196 INT279357 Regulation of Binding of CD28 1 0.18 0.3 0.72
197 INT5211 Localization of Cd40 6 0.78 1.75 0.71
198 INT188586 Negative_regulation of Gene_expression of CD28 6 0.34 1.9 0.69
199 INT116009 Regulation of Negative_regulation of Ifng 1 0.44 0.09 0.67
200 INT265207 Positive_regulation of Gene_expression of Cd28 3 0.43 1.47 0.66
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