GO:0048471

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Name perinuclear region of cytoplasm
Categary Component
Go Slim No
Go Link GO:0048471
Unique Molecular Interactions 4740
Total Molecular Interactions 6559
Total Single Events 56750
Pain Genes Associated 416

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for perinuclear region of cytoplasm. They are ordered first by their pain relevance and then by number of times they were reported for perinuclear region of cytoplasm. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73
2 INT251170 Clu Positive_regulation of Trpv1 1 0.28 2.61 6.49
3 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09
4 INT169218 Binding of EGFR and Coc 1 0.06 2.8 5.85
5 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
6 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
7 INT125407 Binding of OPRL1 and PTPRM 1 0.03 0.72 4.67
8 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
9 INT103724 Oprd1 Positive_regulation of Gtpbp4 3 0.30 0.91 4.18
10 INT130625 Prkcg Regulation of Prkaca 1 0.23 1.32 3.87
11 INT317517 Binding of Nos1 and Oprm1 1 0.17 0.22 3.85
12 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63
13 INT152035 Binding of HLA-A and MRAP 2 0.31 6.95 3.4
14 INT276676 Prkcg Regulation of Nav1 1 0.30 0.82 3.29
15 INT108472 Binding of NOS1 and PNOC 1 0.32 0.64 3.27
16 INT7190 Syt17 Positive_regulation of Ctsb 1 0.16 0 3.23
17 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
18 INT7193 Abl2 Positive_regulation of Ctsb 1 0.21 0 3.21
19 INT275850 Binding of NDUFAB1 and SNCA 1 0.00 3.78 3.16
20 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
21 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12
22 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 0.41 0.62 3.11
23 INT276679 Prkcg Positive_regulation of Positive_regulation of Nkx1-1 1 0.07 0.94 3.08
24 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
25 INT298456 Prkaca Positive_regulation of Phosphorylation of Adarb1 1 0.00 1.86 2.85
26 INT351349 Prkcg Positive_regulation of Binding of Lpar1 1 0.15 2 2.82
27 INT91350 Binding of Pla2g4a and RYBP 1 0.00 1.15 2.65
28 INT150457 Binding of Sort1 and Prss12 3 0.21 1.36 2.64
29 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 0.38 0.86 2.63
30 INT251150 Binding of Nos1 and Dlg2 1 0.30 1.98 2.62
31 INT121742 Prkcg Positive_regulation of Ephb1 3 0.49 0.99 2.6
32 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 1 0.06 0.5 2.6
33 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52
34 INT107812 Nppa Positive_regulation of Localization of Sst 1 0.48 0.54 2.51
35 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
36 INT121746 Prkaca Positive_regulation of Ephb1 2 0.23 0.92 2.35
37 INT321474 Binding of Slc6a2 and Ubqln1 1 0.00 0.8 2.27
38 INT321477 Binding of Ubqln1 and Flvcr2 1 0.00 0.81 2.26
39 INT7195 Negative_regulation of Syt17 Positive_regulation of Ctsb 1 0.10 0 2.25
40 INT251164 Binding of Clu and Trpv1 1 0.19 0.44 2.23
41 INT240131 Binding of Crp and Nppb 7 0.07 11.53 2.12
42 INT281084 Prkaca Positive_regulation of Mapk1 2 0.25 0 2.06
43 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
44 INT121216 Prkca Regulation of Positive_regulation of Oprd1 1 0.02 0.32 2.02
45 INT144115 Positive_regulation of Grm5 Positive_regulation of Prkcg 1 0.41 0 2.01
46 INT163266 Crh Negative_regulation of Tyr 1 0.01 0.45 1.98
47 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
48 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
49 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
50 INT283050 Binding of Gad2 and Trpm8 1 0.23 2.02 1.93
51 INT104855 Prkaca Regulation of TRPV1 3 0.06 1.52 1.92
52 INT165200 Binding of CTLA4 and Crp 1 0.09 1.64 1.91
53 INT112514 Binding of Prkaca and Trib3 1 0.03 1.18 1.9
54 INT186435 Prkcg Regulation of Creb1 1 0.44 0.45 1.9
55 INT186432 Prkaca Regulation of Creb1 1 0.14 0.45 1.9
56 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88
57 INT112517 Binding of Ephb1 and Prkaca 3 0.18 0.58 1.85
58 INT349658 Nos2 Regulation of Gene_expression of Nos1 1 0.63 2.86 1.84
59 INT169468 Binding of Egfr and Spink3 1 0.37 3.73 1.83
60 INT276669 Negative_regulation of Prkcg Regulation of Nav1 1 0.21 0.68 1.82
61 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
62 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
63 INT305741 Binding of Kcnk2 and Sort1 1 0.54 1.01 1.8
64 INT150456 Binding of Sort1 and Nts 3 0.45 0.64 1.79
65 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75
66 INT142899 Chn1 Negative_regulation of Positive_regulation of NOS1 1 0.01 1.07 1.75
67 INT167765 Prkca Positive_regulation of Sigmar1 1 0.41 0.63 1.74
68 INT165183 Ifnb1 Positive_regulation of P2rx4 1 0.04 1.73 1.73
69 INT346217 Braf Positive_regulation of Phosphorylation of Map2k1 1 0.22 3.23 1.72
70 INT139190 Binding of Fadd and Fas 4 0.38 2.65 1.71
71 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
72 INT134363 Prkcg Regulation of ADCY2 1 0.00 0.14 1.7
73 INT157459 Binding of CX3CR1 and CX3CL1 1 0.32 2.12 1.7
74 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
75 INT276672 Binding of Prkcg and Nav1 1 0.16 0.18 1.67
76 INT139433 Binding of Prkaca and Prkca 1 0.37 0.13 1.67
77 INT276680 Binding of Prkcg and Nkx1-1 1 0.05 0.18 1.66
78 INT122428 Binding of Ighm and Prkci 1 0.00 0 1.66
79 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
80 INT144213 Nppa Positive_regulation of Localization of Calca 1 0.71 2.8 1.65
81 INT103725 Negative_regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.17 0.38 1.65
82 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
83 INT103726 Regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.10 0.38 1.64
84 INT122286 Prkaca Negative_regulation of Negative_regulation of Calca 1 0.12 0.54 1.63
85 INT135516 PRKCA Negative_regulation of Phosphorylation of OPRM1 1 0.12 0 1.62
86 INT168612 Negative_regulation of Nos1 Negative_regulation of Positive_regulation of Mmp9 1 0.23 0.45 1.62
87 INT247281 GLC1N Negative_regulation of HRAS 1 0.02 1.98 1.62
88 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
89 INT168607 Negative_regulation of Nos1 Negative_regulation of Mmp9 1 0.23 0.45 1.61
90 INT195930 OPRM1 Regulation of Prkaca 1 0.01 0 1.59
91 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
92 INT342993 PHEX Regulation of Protein_catabolism of SFTPA1 1 0.00 2.84 1.58
93 INT118515 Positive_regulation of PRKCA Positive_regulation of Phosphorylation of TRPV1 1 0.27 0.56 1.58
94 INT54601 Binding of Mtor and Ache 1 0.20 0.8 1.58
95 INT107815 Gene_expression of Sst Positive_regulation of Localization of Nppa 1 0.52 0.27 1.57
96 INT12327 Igh-Dex Positive_regulation of Plec 1 0.03 0.73 1.57
97 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57
98 INT130839 Gfap Positive_regulation of S100B 1 0.51 1.9 1.56
99 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56
100 INT276671 Prkcg Positive_regulation of Nav1 1 0.23 0.21 1.55
101 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
102 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
103 INT121747 Prkcg Negative_regulation of Positive_regulation of Creb1 1 0.16 0.2 1.5
104 INT166676 Binding of PRKCA and UGT1A6 1 0.30 0 1.5
105 INT3573 Tf Negative_regulation of Localization of Gh1 1 0.36 0 1.49
106 INT121741 Prkaca Negative_regulation of Positive_regulation of Creb1 1 0.10 0.2 1.49
107 INT44504 Mt1a Positive_regulation of Prl 1 0.37 0 1.48
108 INT136844 Binding of Prkca and Nrgn 1 0.33 0 1.47
109 INT161870 OPRM1 Positive_regulation of Prkcg 1 0.01 0.12 1.47
110 INT161865 Mors1 Positive_regulation of Prkcg 1 0.00 0.12 1.47
111 INT107813 Sst Negative_regulation of Localization of Nppa 1 0.44 0.2 1.46
112 INT61443 Binding of KNG1 and Tyr 1 0.00 0 1.46
113 INT104972 MITF Regulation of Transcription of TYR 1 0.20 0.35 1.45
114 INT21425 Binding of Pomc and Gtpbp4 1 0.01 0.1 1.45
115 INT150392 Binding of MEFV and PSTPIP1 2 0.51 10.49 1.44
116 INT153581 Binding of Oprm1 and Prkcg 1 0.00 0 1.44
117 INT221242 Ros1 Positive_regulation of Prkca 1 0.02 0.39 1.44
118 INT78974 Binding of Prkcg and Prkaca 2 0.31 0.35 1.4
119 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38
120 INT157460 CX3CL1 Regulation of Gene_expression of COL1A1 1 0.11 1.57 1.37
121 INT122430 Negative_regulation of Binding of Ighm and Prkci 1 0.00 0 1.36
122 INT158079 Binding of Esr1 and Gper 1 0.31 0.97 1.35
123 INT222182 Binding of ESR1 and HLA-DRB2 1 0.00 3.1 1.35
124 INT31772 Ednra Positive_regulation of Nppa 1 0.05 0.13 1.33
125 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
126 INT131888 gr Positive_regulation of Gene_expression of Prkcg 1 0.00 0 1.32
127 INT265213 Binding of Ctla4 and Cd86 2 0.13 1.93 1.31
128 INT120929 Prkcg Regulation of Gene_expression of Fos 2 0.50 0.34 1.31
129 INT150890 Binding of Esr1 and Esr2 2 0.52 2.06 1.31
130 INT131886 Creb1 Positive_regulation of Gene_expression of Prkcg 1 0.03 0 1.31
131 INT169297 TRPV1 Positive_regulation of EGFR 1 0.64 0.37 1.3
132 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
133 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
134 INT124926 Negative_regulation of Prkaca Negative_regulation of Localization of Pag1 1 0.00 0.61 1.3
135 INT135830 Gch1 Regulation of Nos2 1 0.65 0 1.29
136 INT31771 Penk Positive_regulation of Nppa 1 0.22 0.13 1.28
137 INT154203 Binding of Pick1 and Grm7 1 0.41 1.64 1.28
138 INT169289 CNR1 Positive_regulation of EGFR 1 0.62 0.36 1.28
139 INT195929 Binding of OPRM1 and Prkaca 1 0.02 0.33 1.27
140 INT31773 Pdyn Positive_regulation of Nppa 1 0.12 0.13 1.27
141 INT64077 Trpv1 Positive_regulation of Kcnma1 1 0.00 0.37 1.27
142 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
143 INT155663 Positive_regulation of P2rx4 Positive_regulation of Localization of Bdnf 1 0.42 0.84 1.25
144 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
145 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
146 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
147 INT132465 Ltf Positive_regulation of Nos1 1 0.35 0.05 1.24
148 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
149 INT141244 Fos Regulation of Prkaca 1 0.18 0.07 1.24
150 INT195926 Prkaca Positive_regulation of Trpv1 1 0.10 0.44 1.24
151 INT139191 Binding of Fas and RFFL 1 0.00 0.61 1.22
152 INT75229 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.44 0 1.22
153 INT76163 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.02 0.08 1.22
154 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
155 INT7186 Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
156 INT166388 Binding of Gnb2l1 and Mapk1 1 0.49 0.49 1.21
157 INT7184 Negative_regulation of Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
158 INT21424 Binding of Penk and Gtpbp4 1 0.02 0.16 1.2
159 INT228681 Fkbp4 Negative_regulation of Trib3 1 0.00 0.57 1.2
160 INT298454 Prkcg Positive_regulation of Phosphorylation of Adarb1 1 0.00 0.41 1.19
161 INT321475 Slc6a2 Positive_regulation of Ubqln1 1 0.00 0.38 1.19
162 INT120205 Binding of App and Ern1 1 0.05 2.55 1.18
163 INT150835 Gper Positive_regulation of Localization of Prkce 1 0.15 0.62 1.18
164 INT141245 Prkaca Regulation of Gene_expression of Th 1 0.15 0.17 1.17
165 INT85780 Prkaca Regulation of Prkcg 1 0.29 0.47 1.17
166 INT131887 Nr3c1 Regulation of Gene_expression of Prkcg 1 0.01 0 1.17
167 INT189017 Binding of Pax3 and Lmna 1 0.14 0.42 1.16
168 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
169 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
170 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
171 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
172 INT139188 Binding of Daxx and Fas 1 0.03 0.55 1.14
173 INT321473 Binding of Slc6a3 and Ubqln1 1 0.00 0.41 1.13
174 INT289659 Tnfrsf1b Negative_regulation of Mcpt3 1 0.02 0.82 1.13
175 INT130627 Gnas Regulation of Prkaca 1 0.00 0 1.13
176 INT69504 Binding of Nos1 and Gatm 1 0.05 0 1.13
177 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
178 INT130471 Prkcg Regulation of Regulation of Fos 1 0.45 0.27 1.12
179 INT142572 D5Pas1 Negative_regulation of Nos1 2 0.02 0.14 1.11
180 INT62381 ADCY10 Positive_regulation of Localization of IGHG3 1 0.04 0.36 1.11
181 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
182 INT62380 ADCY10 Positive_regulation of IGHG3 1 0.03 0.36 1.11
183 INT317527 Binding of Hint1 and Nos1 1 0.27 0.1 1.11
184 INT64259 Binding of Gtpbp4 and Ptprg 1 0.06 0 1.1
185 INT317512 Binding of Oprm1 and Prkca 1 0.07 0.13 1.1
186 INT308173 Binding of DRG1 and Tnfrsf1b 1 0.01 1.64 1.1
187 INT193328 Grid1 Regulation of Positive_regulation of Prkcg 1 0.00 0.1 1.1
188 INT323175 PRKCA Positive_regulation of Akt1 1 0.02 0 1.1
189 INT167426 Tlr4 Positive_regulation of Localization of Gpt 1 0.25 1.26 1.1
190 INT269200 Prkaca Positive_regulation of Phosphorylation of Ceacam3 1 0.03 0.65 1.09
191 INT130656 Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
192 INT130657 Negative_regulation of Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
193 INT14197 Pde2a Positive_regulation of Localization of Gh1 2 0.04 0 1.08
194 INT305734 Binding of Sort1 and Trpv1 1 0.01 0.5 1.08
195 INT352468 Calca Positive_regulation of Prkaca 1 0.11 0.8 1.08
196 INT96906 Plxna3 Regulation of Regulation of Prkaca 1 0.17 0.71 1.08
197 INT296458 Binding of Gria2 and Pick1 3 0.24 1.86 1.07
198 INT168529 APP Regulation of FSIP1 2 0.65 2.26 1.07
199 INT96905 Plxna3 Regulation of Regulation of Prkce 1 0.18 0.71 1.07
200 INT81582 Plec Positive_regulation of st 1 0.02 0 1.07

Single Events

The table below shows the top 100 pain related interactions that have been reported for perinuclear region of cytoplasm. They are ordered first by their pain relevance and then by number of times they were reported in perinuclear region of cytoplasm. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41
2 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08
3 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47
4 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07
5 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87
6 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91
7 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57
8 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85
9 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71
10 INT47243 Gene_expression of Prkcg 195 0.78 58.05 108.44
11 INT49171 Gene_expression of Nos1 241 0.78 140.7 104.76
12 INT52651 Positive_regulation of Prkaca 136 0.67 40.82 99.16
13 INT65500 Gene_expression of App 605 0.78 429.94 98.31
14 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71
15 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43
16 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32
17 INT12763 Phosphorylation of Prkcg 167 0.82 38.91 89.63
18 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66
19 INT15898 Positive_regulation of Prkaca 199 0.70 50.89 87.54
20 INT5617 Localization of Nppa 266 0.81 83.51 83.89
21 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53
22 INT12536 Localization of Prkcg 101 0.80 36.37 73.81
23 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4
24 INT49111 Negative_regulation of Prkaca 102 0.59 27.44 71.77
25 INT53964 Negative_regulation of Prkaca 131 0.58 38.76 69.52
26 INT39777 Regulation of Prkcg 90 0.62 31.52 68.17
27 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34
28 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64
29 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42
30 INT79093 Positive_regulation of Nos1 101 0.70 46.89 59.61
31 INT49170 Negative_regulation of Nos1 116 0.59 60.66 58.87
32 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97
33 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
34 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15
35 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67
36 INT5623 Positive_regulation of Nppa 174 0.70 69.96 52.33
37 INT64110 Positive_regulation of Gene_expression of Nos1 68 0.70 58.11 51.64
38 INT49028 Positive_regulation of Nos1 102 0.70 34.73 51.05
39 INT48718 Positive_regulation of PRKCA 109 0.69 36.16 46.49
40 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81
41 INT66383 Phosphorylation of Prkaca 143 0.80 30.85 43.38
42 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65
43 INT9298 Positive_regulation of Gtpbp4 64 0.69 12.29 41.97
44 INT57442 Phosphorylation of Prkca 98 0.70 31.58 41.04
45 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94
46 INT64558 Negative_regulation of Nos1 88 0.58 26.76 36.78
47 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69
48 INT48959 Positive_regulation of Positive_regulation of Prkcg 52 0.70 16.47 36.49
49 INT5620 Positive_regulation of Localization of Nppa 105 0.70 30.23 36.45
50 INT30169 Negative_regulation of Pde4a 107 0.58 81 36.23
51 INT79060 Gene_expression of NOS2 116 0.78 69.25 34.84
52 INT12765 Positive_regulation of Phosphorylation of Prkcg 59 0.66 20.16 34.67
53 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89
54 INT12537 Positive_regulation of Localization of Prkcg 36 0.70 14.57 33.81
55 INT51698 Positive_regulation of Gene_expression of Prkcg 44 0.68 14.02 32.9
56 INT89055 Phosphorylation of Prkaca 60 0.61 13.41 32.49
57 INT92837 Negative_regulation of Gene_expression of Nos2 116 0.59 59.67 31.82
58 INT29743 Negative_regulation of App 91 0.59 65.56 31.26
59 INT56809 Binding of Tlr4 184 0.48 106.02 31.18
60 INT64164 Regulation of Prkca 34 0.62 10.44 30.99
61 INT1079 Positive_regulation of Ache 104 0.70 23.52 30.28
62 INT6196 Regulation of Nppa 83 0.62 30.31 30.18
63 INT9133 Negative_regulation of Positive_regulation of Prkcg 37 0.59 10.95 30.06
64 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72
65 INT72252 Gene_expression of Kcnma1 63 0.64 20.47 29.56
66 INT47712 Positive_regulation of App 135 0.69 101.38 28.94
67 INT52712 Negative_regulation of PRKCA 64 0.57 23.11 28.43
68 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
69 INT88046 Gene_expression of Ccr2 38 0.76 33.76 28.07
70 INT66381 Regulation of Prkaca 40 0.62 13.38 27.96
71 INT37296 Binding of Esr1 117 0.43 62.51 27.33
72 INT2569 Gene_expression of Ache 120 0.78 26.29 26.89
73 INT49850 Negative_regulation of PDE4A 105 0.58 76.91 26.59
74 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4
75 INT20462 Binding of ESR1 210 0.44 102.7 26.34
76 INT276 Regulation of Ache 83 0.62 16.75 25.99
77 INT8205 Negative_regulation of Nppa 77 0.59 26.43 25.72
78 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69
79 INT86789 Gene_expression of P2rx4 46 0.77 30.66 25.68
80 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62
81 INT61953 Transcription of Nos2 101 0.72 46.64 25.49
82 INT5622 Gene_expression of Nppa 101 0.78 49.46 25.31
83 INT74688 Regulation of Nos1 55 0.62 22.16 25.3
84 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11
85 INT48766 Regulation of NOS1 73 0.61 37.01 24.59
86 INT96904 Regulation of Prkaca 33 0.44 10.86 24.51
87 INT64076 Positive_regulation of Kcnma1 47 0.40 11.52 24.19
88 INT89854 Regulation of Nos2 49 0.61 42.58 24.1
89 INT4809 Gene_expression of PTGDS 103 0.76 52.94 24.01
90 INT70503 Regulation of Gene_expression of Nos2 71 0.62 44 24.01
91 INT79061 Positive_regulation of NOS2 92 0.65 58.89 23.96
92 INT16431 Localization of Lnpep 62 0.70 6.28 23.94
93 INT44954 Gene_expression of APP 191 0.78 105.86 23.9
94 INT49172 Regulation of Nos1 43 0.52 27.53 23.66
95 INT110427 Gene_expression of Spp1 199 0.78 176.11 23.31
96 INT100026 Gene_expression of Tnfrsf1b 73 0.72 43.26 23.23
97 INT134651 Binding of TLR4 89 0.48 66.96 23.19
98 INT49196 Gene_expression of SELE 105 0.78 107.29 22.92
99 INT82461 Gene_expression of Gad2 40 0.78 19.12 22.79
100 INT87607 Positive_regulation of Prkcc 25 0.69 6.06 22.78
101 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52
102 INT78057 Localization of Tlr4 140 0.77 67.75 21.72
103 INT70504 Regulation of Gene_expression of NOS1 30 0.51 21.72 21.72
104 INT74059 Positive_regulation of Gene_expression of Nos1 55 0.70 11.5 21.39
105 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37
106 INT112427 Positive_regulation of P2rx4 27 0.68 26.29 21.31
107 INT117527 Binding of Prkca 25 0.48 6.43 21.05
108 INT11625 Localization of App 98 0.78 55.46 20.86
109 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78
110 INT89805 Gene_expression of Prkaca 45 0.77 11.03 20.77
111 INT79805 Phosphorylation of PRKCA 57 0.81 23.33 20.41
112 INT66281 Transcription of Nos2 81 0.71 39.49 20.37
113 INT102545 Gene_expression of Ccr2 42 0.78 61.43 19.81
114 INT16794 Binding of App 103 0.48 64.87 19.79
115 INT157463 Gene_expression of CX3CL1 55 0.62 69.05 19.75
116 INT65502 Regulation of App 77 0.62 52.05 19.44
117 INT49487 Gene_expression of Sele 65 0.76 68.11 19.41
118 INT70614 Gene_expression of FAS 118 0.75 112.33 19.01
119 INT113399 Positive_regulation of Pla2g4a 36 0.67 33.83 18.78
120 INT636 Binding of MRAP 54 0.48 40.36 18.77
121 INT30197 Positive_regulation of Ubqln1 26 0.08 2.07 18.28
122 INT187513 Positive_regulation of Pla2g4a 5 0.62 34.09 18.22
123 INT61257 Gene_expression of Sele 79 0.77 70.97 17.78
124 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52
125 INT5618 Regulation of Localization of Nppa 36 0.62 13.42 17.46
126 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33
127 INT17237 Regulation of Esr1 74 0.43 49.09 17.25
128 INT195831 Phosphorylation of Pla2g4a 15 0.74 34.43 17.14
129 INT12922 Gene_expression of Atp9a 115 0.75 50.95 17.01
130 INT65211 Binding of Prkcg 38 0.48 14.75 16.92
131 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79
132 INT61949 Regulation of Nos2 74 0.58 34.08 16.7
133 INT23657 Positive_regulation of APP 64 0.70 39.76 16.68
134 INT52358 Gene_expression of Cx3cr1 25 0.78 18.48 16.65
135 INT77620 Gene_expression of Fas 146 0.78 72.4 16.61
136 INT151434 Positive_regulation of Ccr2 26 0.68 18.34 16.34
137 INT77433 Regulation of Gene_expression of Nos2 49 0.62 35.07 16.33
138 INT19071 Localization of Ache 66 0.81 5.1 16.27
139 INT74545 Negative_regulation of Gene_expression of Prkcg 22 0.42 7.77 16.26
140 INT9525 Regulation of Positive_regulation of Prkcg 20 0.62 7.82 16.18
141 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
142 INT9750 Positive_regulation of Rara 39 0.66 12.44 15.83
143 INT79458 Localization of Prkca 30 0.81 11.13 15.78
144 INT1752 Negative_regulation of Ache 109 0.59 42.05 15.73
145 INT114025 Transcription of Nos1 20 0.70 16.48 15.63
146 INT92354 Localization of ESR1 77 0.75 33.04 15.51
147 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49
148 INT61172 Gene_expression of PRKCA 34 0.77 8.89 15.47
149 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36
150 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15
151 INT74098 Negative_regulation of Gene_expression of Nos1 36 0.59 16.25 14.82
152 INT64112 Regulation of Gene_expression of Nos1 22 0.62 21.45 14.76
153 INT107585 Gene_expression of CCR2 35 0.71 26.44 14.75
154 INT79887 Gene_expression of Prkcc 20 0.78 12.59 14.73
155 INT54052 Gene_expression of App 33 0.78 25.08 14.7
156 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6
157 INT121162 Gene_expression of Cx3cl1 22 0.78 11.56 14.59
158 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46
159 INT63854 Regulation of Gene_expression of Prkcg 27 0.56 9.41 14.15
160 INT77619 Gene_expression of Prkaca 43 0.75 8.55 14.13
161 INT1873 Gene_expression of MRAP 51 0.76 31.75 13.92
162 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78
163 INT52714 Regulation of PRKCA 28 0.61 7.73 13.66
164 INT3623 Negative_regulation of CTSB 49 0.55 27.39 13.52
165 INT21421 Regulation of Gtpbp4 15 0.30 2.7 13.49
166 INT76469 Positive_regulation of Gene_expression of Prkca 18 0.46 7.9 13.36
167 INT12325 Gene_expression of Plec 47 0.72 11.92 13.35
168 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32
169 INT2038 Localization of Esr1 104 0.79 40.12 13.27
170 INT16033 Gene_expression of Ogfr 27 0.73 4.15 13.05
171 INT46619 Gene_expression of CSF1 80 0.73 36.63 12.94
172 INT81629 Positive_regulation of Fas 58 0.70 59.63 12.94
173 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9
174 INT14764 Negative_regulation of Localization of Nppa 28 0.59 11.29 12.82
175 INT90909 Negative_regulation of Gene_expression of NOS1 44 0.55 23.83 12.47
176 INT29745 Binding of APP 47 0.48 26.49 12.4
177 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39
178 INT107916 Protein_catabolism of App 114 1.00 66.71 12.38
179 INT47847 Negative_regulation of Localization of Prkcg 11 0.58 4.02 12.36
180 INT222660 Phosphorylation of Tyr 2 0.06 5.31 12.33
181 INT9083 Gene_expression of Nppb 74 0.78 70.96 12.19
182 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18
183 INT184844 Gene_expression of Snap25 130 0.78 14.32 12.13
184 INT10847 Gene_expression of LAMC2 39 0.75 27 12.09
185 INT148207 Gene_expression of CTLA4 53 0.77 29.13 12.07
186 INT93620 Positive_regulation of Gene_expression of Fasl 51 0.66 59.45 12.04
187 INT122053 Positive_regulation of P2rx4 16 0.69 13.02 11.98
188 INT11121 Positive_regulation of NPPA 64 0.70 34.09 11.96
189 INT92686 Gene_expression of Ctgf 51 0.77 34.4 11.93
190 INT9084 Positive_regulation of Nppb 74 0.70 69.77 11.85
191 INT86698 Gene_expression of Cav1 38 0.78 16.37 11.75
192 INT97381 Negative_regulation of Positive_regulation of Nos2 34 0.59 16.66 11.6
193 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55
194 INT78970 Positive_regulation of Positive_regulation of Prkaca 14 0.47 3.06 11.49
195 INT65501 Regulation of Gene_expression of App 56 0.62 32.51 11.48
196 INT72221 Localization of PRKCA 17 0.81 1.23 11.47
197 INT95369 Positive_regulation of Gene_expression of NOS2 36 0.55 25.09 11.37
198 INT37541 Gene_expression of SPP1 113 0.77 68.54 11.35
199 INT270238 Localization of Pla2g4a 1 0.72 17.99 11.35
200 INT176607 Gene_expression of Cx3cl1 27 0.75 19.51 11.32
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