GO:0048484

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Name enteric nervous system development
Categary Process
Go Slim No
Go Link GO:0048484
Unique Molecular Interactions 304
Total Molecular Interactions 412
Total Single Events 2524
Pain Genes Associated 16

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for enteric nervous system development. They are ordered first by their pain relevance and then by number of times they were reported for enteric nervous system development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
2 INT180774 Gdnf Positive_regulation of Trpv1 1 0.33 2.43 4.37
3 INT122776 Gdnf Positive_regulation of Gene_expression of Trpv1 2 0.67 2.13 3.06
4 INT106560 Binding of Ntf3 and Ntrk2 3 0.14 2.47 2.84
5 INT103330 Ngf Positive_regulation of Gdnf 2 0.28 1.27 2.45
6 INT122775 Gdnf Regulation of Gene_expression of Trpv1 4 0.59 2.72 2.42
7 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
8 INT108129 GDNF Regulation of Gene_expression of GRHL3 1 0.21 0.39 1.71
9 INT180812 Gdnf Positive_regulation of Gene_expression of Sorbs1 1 0.02 0.83 1.61
10 INT180811 Gdnf Positive_regulation of Regulation of Sorbs1 1 0.01 0.83 1.61
11 INT333150 Tlx2 Regulation of asa 1 0.04 2.17 1.55
12 INT170654 Binding of Ntf3 and Ngf 1 0.38 1.66 1.54
13 INT180791 Negative_regulation of Gdnf Regulation of Calca 1 0.17 0 1.47
14 INT180790 Gdnf Regulation of Localization of Trpv1 1 0.15 1.21 1.43
15 INT83197 Binding of Ntrk1 and Gdnf 1 0.01 1.05 1.36
16 INT180802 Gdnf Positive_regulation of Sorbs1 1 0.02 0.98 1.34
17 INT180764 Calca Regulation of Positive_regulation of Gdnf 1 0.21 0 1.32
18 INT242605 Gdnf Positive_regulation of Trpv1 1 0.26 0.17 1.3
19 INT96707 Ntf3 Positive_regulation of Localization of SST 1 0.01 0 1.3
20 INT242623 Binding of Ntf3 and Ntrk3 5 0.22 1.31 1.29
21 INT148435 Binding of Bdnf and Gdnf 2 0.35 1.9 1.17
22 INT180814 Binding of Ret and Gdnf 1 0.01 1.31 1.17
23 INT242625 Gdnf Positive_regulation of Pax3 1 0.01 0.34 1.15
24 INT142413 Oprm1 Positive_regulation of Gdnf 1 0.19 0.29 1.09
25 INT180770 Gdnf Positive_regulation of Zbtb38 1 0.00 0.27 0.99
26 INT147504 Binding of Ncam1 and Gdnf 1 0.31 0.87 0.98
27 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97
28 INT180780 Ngf Regulation of Gdnf 1 0.22 0.28 0.96
29 INT180803 Sorbs1 Regulation of Gdnf 1 0.01 0.28 0.95
30 INT180787 Calca Regulation of Gdnf 1 0.18 0.28 0.95
31 INT147507 Binding of Ret and Gtf3a 1 0.03 0.81 0.92
32 INT147505 Binding of Ret and Gdnf 1 0.27 0.81 0.92
33 INT137092 Ntf3 Negative_regulation of Gene_expression of Gal 1 0.47 1.01 0.9
34 INT242621 Gdnf Positive_regulation of Gene_expression of Scn11a 1 0.05 0.12 0.88
35 INT128701 Ednra Regulation of EDNRB 1 0.17 0.58 0.84
36 INT108128 GDNF Regulation of Localization of GRHL3 1 0.24 0.18 0.83
37 INT103331 Ngf Positive_regulation of Gdnf 1 0.01 0.57 0.8
38 INT220056 Binding of NTF3 and NTRK1 1 0.07 1.12 0.78
39 INT220063 Binding of NTF3 and NTRK2 1 0.09 1.13 0.78
40 INT103334 Gdnf Regulation of Gene_expression of TRPV1 1 0.02 0.53 0.77
41 INT103333 Gdnf Regulation of TRPV1 1 0.02 0.53 0.77
42 INT170658 Binding of Ntf3 and Csf2 1 0.33 0.8 0.74
43 INT180773 Calca Regulation of Binding of Gdnf 1 0.18 0.15 0.72
44 INT180783 Binding of Gdnf and Man2a2 1 0.00 0.52 0.71
45 INT180775 Binding of Gdnf and Gfra1 1 0.06 0.52 0.71
46 INT102121 Gdnf Regulation of Gene_expression of Cnr1 1 0.45 0.42 0.71
47 INT144367 Gdnf Negative_regulation of Positive_regulation of Th 1 0.11 0.77 0.7
48 INT278827 Binding of EDN1 and EDNRB 3 0.17 2.7 0.67
49 INT69205 Ntf3 Positive_regulation of Penk 1 0.06 0.06 0.66
50 INT153921 Positive_regulation of Adra2a Regulation of Ednrb 1 0.01 0 0.66
51 INT338390 Thim Regulation of Gene_expression of Ret 1 0.02 0.43 0.65
52 INT114845 RET Regulation of Gene_expression of Lgals1 1 0.02 0.84 0.65
53 INT122777 Gdnf Negative_regulation of Gene_expression of Trpv1 1 0.36 0.8 0.62
54 INT122774 Gdnf Negative_regulation of Positive_regulation of Trpv1 1 0.32 0.78 0.61
55 INT79747 Ntf3 Regulation of Positive_regulation of Ntrk1 1 0.35 0 0.6
56 INT79740 Ntf3 Regulation of Positive_regulation of Ntrk2 1 0.28 0 0.6
57 INT280895 Runx1 Positive_regulation of Gene_expression of Ret 2 0.33 0.2 0.58
58 INT242584 Gdnf Regulation of Gene_expression of Qrfp 1 0.00 0.09 0.58
59 INT91267 Gdnf Negative_regulation of Gdnf 1 0.05 0.81 0.58
60 INT98034 Binding of Ret and Trpv1 1 0.43 0.42 0.58
61 INT242602 Binding of Ntf3 and Ntrk1 1 0.10 0.14 0.57
62 INT101087 NTF3 Positive_regulation of Gene_expression of IKZF1 1 0.04 0.3 0.55
63 INT278824 Positive_regulation of Binding of EDNRA and EDNRB 1 0.12 1.65 0.53
64 INT242613 Binding of Gfra2 and Ret 1 0.02 0 0.52
65 INT130157 Pomc Regulation of Gene_expression of Ednrb 1 0.14 0 0.52
66 INT79746 Ntf3 Positive_regulation of Gene_expression of Sst 1 0.42 0 0.52
67 INT242598 Binding of Gdnf and Gfra2 4 0.16 0.38 0.51
68 INT333168 Tlx2 Negative_regulation of Gene_expression of Vcam1 1 0.14 0.71 0.51
69 INT242614 Binding of Gdnf and Gfra1 1 0.03 0 0.51
70 INT356279 Gdnf Regulation of Positive_regulation of Mapk1 1 0.03 0.76 0.5
71 INT98117 Gdnf Regulation of SCN11A 1 0.05 0.39 0.5
72 INT242597 Gene_expression of Gdnf Negative_regulation of Trpv1 1 0.27 0.08 0.5
73 INT98116 Gdnf Regulation of SCN10A 1 0.03 0.39 0.5
74 INT278825 Positive_regulation of Binding of EDN1 and EDNRB 3 0.16 1.24 0.49
75 INT242638 Binding of BDNF and Gdnf 1 0.29 0 0.49
76 INT108692 NTF3 Regulation of Gene_expression of IKZF1 1 0.69 0.7 0.49
77 INT242600 Binding of Gdnf and Gopc 1 0.06 0 0.49
78 INT165582 Binding of Bdnf and Gdnf 1 0.36 0.47 0.49
79 INT242604 Gdnf Regulation of Gene_expression of Trpv1 1 0.17 0.36 0.48
80 INT333156 Tlx2 Regulation of Gene_expression of Icam1 1 0.06 0.59 0.48
81 INT96709 Ntf3 Regulation of Localization of SST 1 0.01 0 0.46
82 INT242628 Binding of Gfra1 and Ret 1 0.03 0 0.46
83 INT242615 Ret Positive_regulation of Gene_expression of Gfra1 1 0.04 0 0.46
84 INT242596 Binding of Ntrk1 and Ret 1 0.12 0 0.46
85 INT98119 Gdnf Regulation of SCN10A 1 0.01 0.34 0.45
86 INT96710 Ntf3 Regulation of BDNF 1 0.02 0 0.45
87 INT98118 Gdnf Regulation of SCN11A 1 0.01 0.34 0.45
88 INT104459 Gdnf Regulation of Ngf 1 0.26 0.56 0.45
89 INT170656 Ntf3 Positive_regulation of Csf2 1 0.35 1.46 0.44
90 INT127074 Gdnf Regulation of Gene_expression of Jun 1 0.10 0.28 0.43
91 INT170657 Ntf3 Regulation of Csf2 1 0.31 0.46 0.43
92 INT127072 Gdnf Regulation of Gene_expression of Fos 1 0.38 0.28 0.43
93 INT127077 Gdnf Positive_regulation of Gene_expression of IER3 1 0.02 0.26 0.42
94 INT127079 Gene_expression of Gdnf Positive_regulation of Gene_expression of IER3 1 0.02 0.26 0.42
95 INT80824 NGF Positive_regulation of NTF3 1 0.47 0.26 0.42
96 INT139654 Ntf3 Regulation of Gene_expression of Grin1 1 0.56 0.11 0.41
97 INT148436 Binding of Gdnf and Ngf 1 0.35 1.14 0.4
98 INT148438 Binding of Bdnf and Ntf3 1 0.33 1.14 0.4
99 INT242607 Negative_regulation of Ntrk1 Positive_regulation of Ret 1 0.16 0 0.39
100 INT78627 Gdnf Negative_regulation of Negative_regulation of P2rx3 1 0.00 0.42 0.38
101 INT73537 Ntf3 Positive_regulation of Ngfr 1 0.21 0.1 0.38
102 INT140869 Binding of Gdnf and Trib3 1 0.04 0.15 0.37
103 INT137625 Ntf3 Positive_regulation of Atp7b 1 0.04 0 0.36
104 INT152315 Ifng Regulation of Ednrb 1 0.19 0.22 0.36
105 INT223470 Ret Regulation of Ntrk1 1 0.21 0 0.36
106 INT152313 Il18 Regulation of Ednrb 1 0.30 0.22 0.36
107 INT201068 Binding of Edn1 and Ednrb 2 0.18 1.23 0.35
108 INT137438 Ntf3 Regulation of Sema3a 1 0.06 0.82 0.35
109 INT148240 Binding of Kit and Ret 1 0.24 0.44 0.35
110 INT137439 Ntf3 Negative_regulation of Sema3a 1 0.02 0.77 0.34
111 INT201484 Negative_regulation of Prkcg Negative_regulation of Positive_regulation of Ednrb 1 0.34 0.96 0.32
112 INT333154 Tlx2 Regulation of Gene_expression of asa 1 0.07 0.18 0.32
113 INT333163 asa Regulation of Gene_expression of Tlx2 1 0.07 0.18 0.32
114 INT333166 Tlx2 Positive_regulation of Gene_expression of Nos3 1 0.08 0.18 0.32
115 INT333155 Tlx2 Regulation of Gene_expression of Nos3 1 0.08 0.18 0.32
116 INT333152 Tlx2 Positive_regulation of Nos3 1 0.08 0.18 0.32
117 INT333167 Tlx2 Regulation of Nos3 1 0.08 0.18 0.32
118 INT284137 EDNRB Regulation of EDNRA 1 0.07 0.09 0.3
119 INT144210 Bdnf Regulation of Ntf3 1 0.20 0.78 0.3
120 INT356278 Gdnf Positive_regulation of Mapk1 1 0.05 0.17 0.3
121 INT356282 Gdnf Positive_regulation of Trib3 1 0.00 0.17 0.3
122 INT245563 Negative_regulation of Runx1 Regulation of Ret 1 0.39 0.76 0.29
123 INT245556 Runx1 Regulation of Ret 1 0.56 0.76 0.29
124 INT333159 Tlx2 Negative_regulation of Gene_expression of Thbd 1 0.12 0.53 0.28
125 INT180788 Gdnf Regulation of Trpv1 1 0.13 0.2 0.28
126 INT166605 Binding of BDNF and Ntf3 1 0.16 0.46 0.28
127 INT166610 Binding of BDNF and Ntf3 1 0.03 0.46 0.28
128 INT56056 Binding of Ntf3 and Tfg 1 0.04 0.49 0.25
129 INT56058 Negative_regulation of Binding of Ntf3 and Tfg 1 0.05 0.5 0.25
130 INT146217 Binding of NTF3 and Ngf 1 0.08 0.11 0.24
131 INT146212 Binding of Ngf and Ntf3 1 0.00 0.11 0.24
132 INT284139 EDNRB Positive_regulation of Gene_expression of EDNRA 1 0.12 0.45 0.22
133 INT277434 Cd5 Regulation of Gdnf 1 0.01 0 0.21
134 INT333171 Tlx2 Positive_regulation of Blnk 1 0.03 0.37 0.19
135 INT242632 Ret Positive_regulation of Gene_expression of Trpa1 1 0.33 0.09 0.18
136 INT108662 Ntf3 Positive_regulation of Trpv1 1 0.17 0.28 0.17
137 INT264276 Binding of Ednrb and P2rx1 1 0.00 0.17 0.16
138 INT243524 Positive_regulation of Binding of NTF3 and SOX10 1 0.01 0.54 0.14
139 INT243525 Binding of NTF3 and SOX10 1 0.01 0.54 0.14
140 INT89940 Ednrb Positive_regulation of Positive_regulation of TNF 1 0.01 0.09 0.14
141 INT326385 Mtdh Regulation of Gdnf 1 0.00 0.41 0.14
142 INT193551 Mtpn Positive_regulation of Gene_expression of Gdnf 1 0.02 0.34 0.13
143 INT347868 Ntf3 Negative_regulation of Negative_regulation of Chat 1 0.03 0.22 0.13
144 INT193552 Gdnf Positive_regulation of Gene_expression of Mtpn 1 0.02 0.34 0.13
145 INT89939 Ednrb Regulation of Gene_expression of TNF 1 0.00 0.09 0.13
146 INT277433 Wibg Positive_regulation of Gdnf 1 0.01 0.6 0.13
147 INT277430 Wibg Positive_regulation of Gene_expression of Gdnf 1 0.01 0.6 0.13
148 INT193548 Gdnf Positive_regulation of Ephb1 1 0.40 0.34 0.13
149 INT141281 ARTN Regulation of Gdnf 1 0.48 0.32 0.12
150 INT227701 Tlx2 Positive_regulation of Regulation of SSRP1 1 0.00 0.69 0.12
151 INT141279 Nrtn Regulation of Gdnf 1 0.14 0.32 0.12
152 INT141280 PSPN Regulation of Gdnf 1 0.48 0.32 0.12
153 INT96518 Regulation of Gdnf Positive_regulation of Ret 1 0.00 0.23 0.11
154 INT334871 Binding of Mpz and Sox10 1 0.13 0 0.11
155 INT258527 Binding of BRAF and RET 1 0.21 1.49 0.11
156 INT334862 Positive_regulation of Binding of Mpz and Sox10 1 0.17 0 0.11
157 INT213554 Gdnf Regulation of Bdnf 1 0.13 0.14 0.1
158 INT213550 Bdnf Regulation of Gdnf 1 0.13 0.14 0.1
159 INT284140 Binding of EDNRB and PAH 1 0.08 0.1 0.1
160 INT96519 Gdnf Positive_regulation of Ret 1 0.00 0.22 0.1
161 INT242627 Ngf Positive_regulation of Gene_expression of Ret 1 0.32 0.1 0.1
162 INT258522 Binding of DDR1 and RET 1 0.03 1.05 0.1
163 INT273791 Ntf3 Positive_regulation of Nfasc 1 0.01 0.18 0.09
164 INT356275 Gdnf Positive_regulation of Phosphorylation of Mapk1 1 0.05 0.21 0.09
165 INT242594 Binding of Gdnf and Ret 1 0.21 0 0.08
166 INT178072 Gene_expression of EDNRB Positive_regulation of EDN3 1 0.05 1.11 0.08
167 INT181584 Binding of EDNRB and Edn1 1 0.46 0.85 0.08
168 INT137632 Rasa1 Regulation of Ednrb 1 0.05 0 0.08
169 INT178100 Gene_expression of EDNRB Positive_regulation of EDN1 1 0.17 1.11 0.08
170 INT326381 Binding of Gdnf and Pcdhb16 1 0.00 0.3 0.08
171 INT326382 Binding of Gdnf and Ncam1 1 0.01 0.3 0.08
172 INT277431 Positive_regulation of Grm3 Positive_regulation of Gene_expression of Gdnf 1 0.18 0 0.07
173 INT178093 EDN3 Positive_regulation of Gene_expression of EDNRB 1 0.05 1.01 0.07
174 INT192907 Edn1 Positive_regulation of Ednrb 1 0.10 0.35 0.07
175 INT178096 EDN1 Positive_regulation of Gene_expression of EDNRB 1 0.17 1.01 0.07
176 INT277432 Ptpn2 Positive_regulation of Gdnf 1 0.29 1.41 0.06
177 INT242636 Ret Positive_regulation of Gene_expression of Slc18a3 1 0.20 0 0.06
178 INT81151 NTF4 Regulation of Ntf3 1 0.02 0 0.06
179 INT137870 Binding of Artn and Ret 1 0.25 0.16 0.05
180 INT112282 Ntf3 Regulation of Igf1 1 0.07 0.14 0.05
181 INT112280 Ntf3 Regulation of Cntf 1 0.11 0.13 0.05
182 INT306513 EDN3 Positive_regulation of EDNRB 1 0.14 0.98 0.04
183 INT306514 EDN1 Positive_regulation of EDNRB 1 0.11 0.98 0.04
184 INT79985 Gdnf Negative_regulation of Negative_regulation of GAD1 1 0.04 0.46 0.04
185 INT79986 Gdnf Negative_regulation of Gene_expression of GAD1 1 0.03 0.46 0.04
186 INT246450 Lta Positive_regulation of Ednrb 1 0.00 0 0.04
187 INT242601 Gdnf Positive_regulation of Chat 1 0.29 0.15 0.03
188 INT334867 Binding of C4b and Sox10 1 0.04 0 0.03
189 INT256228 EDNRB Positive_regulation of EDN1 1 0.26 0.62 0.03
190 INT277429 Ptpn2 Regulation of Gdnf 1 0.34 0.47 0.03
191 INT239225 Binding of Edn1 and Ednrb 1 0.02 0.36 0.03
192 INT334872 Positive_regulation of Binding of C4b and Sox10 1 0.04 0 0.03
193 INT199159 Binding of RET and Pheo 1 0.04 1.42 0.03
194 INT277427 Ptpn2 Positive_regulation of Gene_expression of Gdnf 1 0.32 0.47 0.03
195 INT239228 Regulation of Binding of Edn1 and Ednrb 1 0.02 0.37 0.03
196 INT334864 Positive_regulation of Binding of Nfatc1 and Sox10 1 0.04 0 0.03
197 INT334873 Binding of Nfatc1 and Sox10 1 0.02 0 0.03
198 INT239224 Positive_regulation of Binding of Edn1 and Ednrb 1 0.02 0.37 0.03
199 INT277428 Positive_regulation of Ptpn2 Positive_regulation of Gdnf 1 0.29 0.47 0.03
200 INT115368 Binding of GDNF and RAPGEF5 1 0.32 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for enteric nervous system development. They are ordered first by their pain relevance and then by number of times they were reported in enteric nervous system development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16258 Gene_expression of Ntf3 121 0.78 53.93 59.03
2 INT74389 Gene_expression of Gdnf 131 0.78 58.52 57.06
3 INT48890 Gene_expression of Gdnf 91 0.77 28.62 31.49
4 INT79979 Gene_expression of Ret 94 0.75 19.21 25.51
5 INT77793 Positive_regulation of Gdnf 54 0.70 23.76 25.08
6 INT69203 Positive_regulation of Ntf3 43 0.66 19.16 16.49
7 INT97871 Gene_expression of Ntf3 47 0.78 25.9 15.94
8 INT102897 Positive_regulation of Gene_expression of Gdnf 34 0.69 11.13 13.28
9 INT75224 Positive_regulation of Gene_expression of Ntf3 23 0.69 11.79 13.08
10 INT16256 Regulation of Ntf3 15 0.49 9.75 13.07
11 INT16255 Negative_regulation of Ntf3 21 0.51 12.92 11.93
12 INT79981 Positive_regulation of Gene_expression of Gdnf 27 0.70 12.49 10.77
13 INT82950 Positive_regulation of Gdnf 36 0.51 11.72 10.5
14 INT85844 Regulation of Gdnf 18 0.50 11.08 10.43
15 INT55014 Positive_regulation of Ednrb 31 0.70 16.61 9.68
16 INT21952 Gene_expression of GDNF 42 0.78 20.32 9.62
17 INT98111 Negative_regulation of Gdnf 12 0.59 10.85 9.29
18 INT64849 Gene_expression of Ret 24 0.75 14.36 9.1
19 INT77795 Localization of Gdnf 26 0.81 6.29 8.55
20 INT77794 Binding of Gdnf 15 0.48 8.38 8.22
21 INT71689 Localization of Ntf3 23 0.73 11.1 7.91
22 INT92003 Positive_regulation of Transcription of Gdnf 10 0.66 5.54 7.84
23 INT97870 Positive_regulation of Gene_expression of Ntf3 19 0.70 9.56 7.8
24 INT87546 Transcription of Gdnf 15 0.71 7.49 7.76
25 INT92001 Regulation of Gene_expression of Gdnf 12 0.62 6.62 6.65
26 INT78178 Gene_expression of Ednrb 21 0.75 7.1 6.37
27 INT92662 Negative_regulation of Gene_expression of Ntf3 9 0.57 7.44 6.22
28 INT87548 Negative_regulation of Gene_expression of Gdnf 9 0.54 5.67 5.94
29 INT119523 Gene_expression of EDNRB 32 0.75 26.47 5.75
30 INT115087 Negative_regulation of Gdnf 10 0.51 5.78 5.73
31 INT16257 Regulation of Gene_expression of Ntf3 8 0.43 4 5.63
32 INT126505 Positive_regulation of Ntf3 26 0.70 9.17 4.92
33 INT78626 Regulation of Gdnf 7 0.45 3.3 4.64
34 INT29519 Gene_expression of Ednrb 8 0.66 1.99 4.55
35 INT92133 Negative_regulation of Ednrb 8 0.42 1.7 4.44
36 INT152312 Positive_regulation of Ednrb 7 0.49 1.46 4.04
37 INT75996 Transcription of Ntf3 13 0.67 4.03 3.88
38 INT88008 Positive_regulation of Gene_expression of GDNF 14 0.70 8.9 3.61
39 INT242569 Positive_regulation of Ret 17 0.55 3.61 3.54
40 INT78625 Regulation of Gene_expression of Gdnf 7 0.37 2.5 3.47
41 INT84222 Regulation of Ednrb 4 0.45 2.24 3.25
42 INT101239 Gene_expression of NTF3 9 0.76 5.91 2.97
43 INT209744 Transcription of Gdnf 5 0.67 1.36 2.84
44 INT128774 Regulation of Gene_expression of Ednrb 3 0.46 1 2.56
45 INT38631 Positive_regulation of Ret 8 0.39 3.23 2.52
46 INT115474 Positive_regulation of Tlx2 5 0.70 4.03 2.44
47 INT63333 Gene_expression of RET 24 0.76 30.09 2.41
48 INT144366 Negative_regulation of Positive_regulation of Gdnf 4 0.41 1.43 2.41
49 INT37057 Gene_expression of Tlx2 12 0.76 7.98 2.38
50 INT242548 Regulation of Gene_expression of Ret 7 0.49 1.2 2.33
51 INT98650 Positive_regulation of Localization of Gdnf 4 0.68 0.94 2.27
52 INT139648 Localization of Ntf3 7 0.66 3.73 2.22
53 INT50392 Regulation of Ret 6 0.54 3.51 2.22
54 INT242551 Negative_regulation of Gene_expression of Ret 5 0.41 1.01 2.21
55 INT78177 Negative_regulation of Gene_expression of Ednrb 4 0.41 1.04 2.16
56 INT98652 Positive_regulation of Localization of Ntf3 2 0.40 1.42 2.15
57 INT88006 Positive_regulation of GDNF 5 0.45 2.55 2.14
58 INT102896 Binding of Ret 8 0.35 1.55 2.03
59 INT180801 Regulation of Binding of Gdnf 1 0.20 1.31 2.03
60 INT209745 Positive_regulation of Transcription of Gdnf 4 0.58 0.97 1.91
61 INT56054 Negative_regulation of Ntf3 7 0.59 2.75 1.86
62 INT178130 Binding of EDNRB 12 0.36 6.18 1.84
63 INT280889 Gene_expression of Sox10 19 0.72 3.45 1.78
64 INT105200 Binding of Ntf3 6 0.31 2.46 1.67
65 INT201475 Negative_regulation of Positive_regulation of Ednrb 6 0.42 3.74 1.66
66 INT93182 Binding of Gdnf 7 0.35 1.96 1.64
67 INT167145 Regulation of Gene_expression of Ntf3 6 0.54 3.4 1.64
68 INT98651 Regulation of Positive_regulation of Gdnf 3 0.44 0.97 1.58
69 INT21951 Negative_regulation of Gene_expression of GDNF 5 0.43 2.82 1.57
70 INT242572 Positive_regulation of Gene_expression of Ret 6 0.40 0.29 1.56
71 INT126504 Regulation of Ntf3 5 0.39 4.3 1.54
72 INT139514 Localization of EDNRB 7 0.73 4.63 1.52
73 INT114298 Positive_regulation of Gene_expression of Ednrb 4 0.36 0.79 1.42
74 INT87547 Negative_regulation of Transcription of Gdnf 1 0.58 1.24 1.4
75 INT60772 Negative_regulation of Ednrb 8 0.41 4.56 1.39
76 INT108130 Localization of GDNF 3 0.74 1.36 1.38
77 INT98653 Negative_regulation of Localization of Gdnf 1 0.57 0.31 1.35
78 INT44746 Localization of Ret 3 0.48 1.23 1.28
79 INT81368 Binding of Ntf3 5 0.34 2.09 1.23
80 INT223448 Localization of Ret 2 0.60 0.58 1.23
81 INT180795 Positive_regulation of Positive_regulation of Gdnf 2 0.29 0.1 1.07
82 INT109396 Negative_regulation of RET 12 0.42 14.92 1.06
83 INT108985 Negative_regulation of Regulation of Gdnf 1 0.43 1.11 1.04
84 INT133842 Binding of SOX10 3 0.38 5.79 1.02
85 INT71690 Negative_regulation of Negative_regulation of Ntf3 2 0.36 1.3 1.01
86 INT51382 Binding of Tlx2 3 0.37 1.03 0.99
87 INT208932 Regulation of Ret 6 0.49 1.49 0.97
88 INT78181 Negative_regulation of EDNRB 6 0.57 4.46 0.95
89 INT2425 Negative_regulation of Ret 3 0.58 1.77 0.94
90 INT75994 Positive_regulation of Transcription of Ntf3 2 0.07 0.62 0.94
91 INT139515 Positive_regulation of EDNRB 15 0.67 10.35 0.93
92 INT243533 Positive_regulation of SOX10 1 0.35 3.93 0.92
93 INT92002 Transcription of Ret 3 0.43 1.58 0.9
94 INT83461 Binding of RET 8 0.47 9.7 0.87
95 INT92623 Regulation of Positive_regulation of Ntf3 2 0.09 1 0.83
96 INT133841 Gene_expression of SOX10 18 0.67 9.96 0.8
97 INT178127 Positive_regulation of Gene_expression of EDNRB 7 0.51 5.24 0.78
98 INT121947 Negative_regulation of Positive_regulation of Gdnf 1 0.20 0.07 0.76
99 INT79784 Positive_regulation of RET 15 0.57 17.43 0.71
100 INT114842 Localization of RET 3 0.71 5.98 0.71
101 INT66940 Regulation of RET 7 0.52 5.61 0.69
102 INT236094 Localization of Gdnf 4 0.70 2.51 0.68
103 INT96704 Negative_regulation of Positive_regulation of Ntf3 2 0.37 0 0.68
104 INT209746 Regulation of Positive_regulation of Gdnf 2 0.37 0.11 0.68
105 INT139513 Negative_regulation of Localization of EDNRB 2 0.41 0 0.62
106 INT241673 Phosphorylation of GDNF 2 0.79 1.06 0.61
107 INT249452 Localization of NTF3 4 0.48 1.21 0.6
108 INT80825 Binding of NTF3 3 0.37 0.42 0.6
109 INT114299 Transcription of Ednrb 2 0.19 0.32 0.59
110 INT85138 Binding of GDNF 6 0.37 2.01 0.58
111 INT98112 Positive_regulation of Negative_regulation of Gdnf 1 0.05 0.44 0.57
112 INT91993 Regulation of Gene_expression of Ret 3 0.42 2.42 0.55
113 INT170652 Positive_regulation of Regulation of Ntf3 1 0.43 0.99 0.51
114 INT108693 Transcription of NTF3 1 0.67 0.71 0.5
115 INT245546 Negative_regulation of Positive_regulation of Ret 2 0.34 0.89 0.49
116 INT115138 Localization of Tlx2 2 0.66 2.14 0.49
117 INT243538 Regulation of SOX10 1 0.31 3.27 0.48
118 INT230623 Negative_regulation of SOX10 2 0.36 0.46 0.46
119 INT127069 Regulation of Localization of Gdnf 1 0.34 0.46 0.46
120 INT201478 Regulation of Positive_regulation of Ednrb 1 0.35 0.68 0.44
121 INT181152 Regulation of Tlx2 2 0.07 2.66 0.43
122 INT166599 Negative_regulation of Gene_expression of Ntf3 2 0.47 2.72 0.43
123 INT140868 Positive_regulation of Gene_expression of Ret 1 0.50 0.32 0.42
124 INT98649 Regulation of Regulation of Ntf3 1 0.06 0.15 0.41
125 INT131106 Positive_regulation of Positive_regulation of Ednrb 1 0.15 0.91 0.4
126 INT148433 Negative_regulation of Binding of Gdnf 1 0.41 1.14 0.4
127 INT148434 Negative_regulation of Binding of Ntf3 1 0.39 1.14 0.4
128 INT166598 Phosphorylation of Ntf3 2 0.56 0.55 0.36
129 INT324117 Positive_regulation of NTF3 1 0.21 0 0.36
130 INT201476 Positive_regulation of Negative_regulation of Ednrb 1 0.49 0.62 0.36
131 INT245522 Positive_regulation of Localization of Ntf3 1 0.29 0.88 0.34
132 INT88012 Regulation of Gene_expression of GDNF 2 0.43 0.48 0.31
133 INT350971 Negative_regulation of Binding of EDNRB 1 0.13 0.86 0.29
134 INT242536 Negative_regulation of Gene_expression of Gdnf 1 0.30 0.06 0.28
135 INT108694 Positive_regulation of Gene_expression of NTF3 1 0.46 0.37 0.27
136 INT222027 Negative_regulation of Transcription of Ntf3 1 0.29 0.41 0.27
137 INT333146 Positive_regulation of Gene_expression of Tlx2 1 0.16 0.12 0.27
138 INT139512 Positive_regulation of Localization of EDNRB 3 0.37 0.69 0.26
139 INT242520 Negative_regulation of Ret 1 0.35 2.49 0.26
140 INT167146 Transcription of Ntf3 2 0.69 0.52 0.21
141 INT55013 Localization of Ednrb 2 0.16 0.98 0.18
142 INT216383 Negative_regulation of NTF3 1 0.23 0.2 0.18
143 INT274098 Regulation of EDNRB 1 0.33 2.41 0.18
144 INT88007 Regulation of GDNF 2 0.34 0.82 0.16
145 INT243532 Positive_regulation of Gene_expression of SOX10 1 0.55 0.86 0.15
146 INT243529 Regulation of Gene_expression of SOX10 1 0.31 1.27 0.15
147 INT242342 Regulation of Ednrb 1 0.09 2.03 0.15
148 INT256229 Protein_catabolism of EDNRB 3 0.64 0.96 0.14
149 INT305524 Positive_regulation of Sox10 2 0.39 0.36 0.14
150 INT280888 Localization of Sox10 1 0.69 0.06 0.13
151 INT277419 Positive_regulation of Positive_regulation of Gdnf 1 0.47 0 0.12
152 INT153553 Positive_regulation of Gene_expression of RET 1 0.67 1.38 0.12
153 INT88013 Transcription of GDNF 2 0.40 0.22 0.11
154 INT126506 Positive_regulation of Positive_regulation of Ntf3 2 0.47 0.32 0.11
155 INT305529 Negative_regulation of Positive_regulation of Sox10 1 0.33 0.36 0.11
156 INT88011 Positive_regulation of Transcription of GDNF 1 0.35 0.22 0.11
157 INT181153 Regulation of Positive_regulation of Tlx2 1 0.07 0.91 0.1
158 INT280891 Transcription of Sox10 2 0.64 0.28 0.08
159 INT242576 Positive_regulation of Regulation of Ret 1 0.35 0.09 0.08
160 INT277418 Regulation of Binding of Gdnf 1 0.42 0 0.08
161 INT347981 Positive_regulation of Phosphorylation of Gdnf 1 0.11 0.79 0.07
162 INT153554 Positive_regulation of Binding of RET 1 0.45 0.83 0.07
163 INT347993 Regulation of Phosphorylation of Gdnf 1 0.10 0.87 0.07
164 INT347980 Phosphorylation of Gdnf 1 0.19 0.79 0.07
165 INT324892 Binding of Ednrb 1 0.06 0.32 0.06
166 INT208455 Protein_catabolism of Ntf3 1 0.23 0.75 0.06
167 INT208456 Positive_regulation of Protein_catabolism of Ntf3 1 0.16 0.75 0.06
168 INT199153 Phosphorylation of RET 1 0.44 1.73 0.04
169 INT292130 Negative_regulation of Gene_expression of RET 1 0.12 1.37 0.04
170 INT242574 Positive_regulation of Positive_regulation of Ret 1 0.40 0.12 0.04
171 INT222030 Negative_regulation of Localization of Ntf3 1 0.25 0.18 0.04
172 INT356267 Binding of Ret 1 0.08 0 0.03
173 INT264273 Localization of Ednrb 1 0.01 0 0.03
174 INT244785 Localization of Foxd3 1 0.27 0 0.03
175 INT280886 Regulation of Sox10 2 0.42 0.15 0
176 INT167144 Regulation of Positive_regulation of Ntf3 2 0.45 0.06 0
177 INT280890 Positive_regulation of Gene_expression of Sox10 2 0.46 0.35 0
178 INT326698 Regulation of Gene_expression of Sox10 1 0.35 0.06 0
179 INT243531 Localization of SOX10 1 0.52 0.31 0
180 INT273282 Negative_regulation of Gene_expression of Tlx2 1 0.19 0.52 0
181 INT161357 Transcription of SOX10 1 0.25 0.17 0
182 INT244772 Gene_expression of Foxd3 1 0.62 0 0
183 INT244753 Negative_regulation of Foxd3 1 0.34 0 0
184 INT284148 Positive_regulation of Positive_regulation of EDNRB 1 0.29 0.54 0
185 INT338104 Transcription of RET 1 0.54 0.59 0
186 INT156925 Positive_regulation of Positive_regulation of Ntf3 1 0.44 0 0
187 INT326714 Negative_regulation of Sox10 1 0.34 0.68 0
188 INT244745 Positive_regulation of Foxd3 1 0.56 0 0
189 INT331205 Protein_catabolism of Gdnf 1 0.03 0.57 0
190 INT242580 Regulation of Positive_regulation of Ret 1 0.36 0.69 0
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