GO:0048488

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Name synaptic vesicle endocytosis
Categary Process
Go Slim No
Go Link GO:0048488
Unique Molecular Interactions 89
Total Molecular Interactions 107
Total Single Events 1009
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for synaptic vesicle endocytosis. They are ordered first by their pain relevance and then by number of times they were reported for synaptic vesicle endocytosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT275850 Binding of NDUFAB1 and SNCA 1 0.00 3.78 3.16
2 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
3 INT214370 Slc6a3 Regulation of Amph 1 0.14 0.44 0.82
4 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
5 INT191332 AMPH Positive_regulation of Mapk1 1 0.76 0 0.66
6 INT191330 AMPH Positive_regulation of Vta1 1 0.07 0 0.66
7 INT191331 AMPH Positive_regulation of Gene_expression of Vta1 1 0.07 0 0.66
8 INT149321 Amph Positive_regulation of Trib3 1 0.16 0 0.54
9 INT273235 Binding of Cdk5 and Cdk5r1 1 0.24 6.06 0.46
10 INT324802 Binding of Cd24a and Siglecg 1 0.03 1.34 0.4
11 INT273234 Negative_regulation of Cdk5 Positive_regulation of Ptprs 1 0.14 1.26 0.34
12 INT214377 Akt1 Regulation of Amph 1 0.15 0 0.33
13 INT214371 Amph Positive_regulation of Ubqln1 1 0.01 0 0.3
14 INT214373 Negative_regulation of Amph Positive_regulation of Ubqln1 1 0.01 0 0.3
15 INT328407 Nlrp1a Negative_regulation of Gene_expression of Snca 1 0.07 0.31 0.29
16 INT328410 Nlrp1a Negative_regulation of Snca 1 0.07 0.31 0.29
17 INT298995 Il18 Positive_regulation of Gene_expression of Cdk5 1 0.12 1.65 0.29
18 INT299008 Il18 Positive_regulation of Transcription of Cdk5 1 0.12 1.65 0.29
19 INT247949 Cdk5r1 Positive_regulation of Cdk5 1 0.26 1.12 0.28
20 INT149322 Amph Positive_regulation of Akt1 1 0.39 0 0.27
21 INT337113 Ppp1r1b Negative_regulation of Phosphorylation of Cdk5 1 0.11 0.28 0.27
22 INT273232 Negative_regulation of Binding of Cdk5 and Cdk5r1 1 0.28 3.16 0.23
23 INT190045 Binding of Ebp and Scrib 1 0.10 0.79 0.22
24 INT273237 Cdk5 Positive_regulation of Protein_catabolism of Grin2b 1 0.45 1.31 0.22
25 INT214367 Amph Positive_regulation of Localization of Ubqln1 1 0.01 0 0.21
26 INT326834 Cdk5r2 Positive_regulation of Cdk5 1 0.02 0.96 0.21
27 INT324824 Positive_regulation of Binding of Cd24a and Siglecg 1 0.03 0.68 0.2
28 INT64964 Binding of Alb and Cd24 1 0.02 0.2 0.2
29 INT221956 CDK5R1 Regulation of Positive_regulation of CDK5 1 0.21 0.62 0.19
30 INT324822 Binding of Cd24a and Hsp90aa1 1 0.10 0.71 0.19
31 INT324797 Binding of Cd24a and Hmgb1 1 0.19 0.66 0.19
32 INT317322 Snca Regulation of Positive_regulation of Th 1 0.01 0.23 0.17
33 INT298998 Il18 Positive_regulation of Cdk5 1 0.11 0.36 0.17
34 INT164791 Cdk5r1 Positive_regulation of Cdk5 1 0.30 0.25 0.17
35 INT57175 D230030E09Rik Negative_regulation of Amph 1 0.05 0 0.17
36 INT214375 Amph Regulation of Ubqln1 1 0.00 0 0.16
37 INT273233 Negative_regulation of Cdk5 Negative_regulation of Positive_regulation of Ltp 1 0.20 0.39 0.13
38 INT337676 Binding of TIMP1 and Scrib 1 0.01 1.24 0.13
39 INT273239 Cdk5 Positive_regulation of Positive_regulation of GRIN1 1 0.51 0.37 0.12
40 INT253328 Binding of IL8 and Scrib 1 0.04 0.79 0.12
41 INT158141 Binding of HOXD13 and SNCA 1 0.54 0.41 0.11
42 INT221958 CDK5R1 Positive_regulation of Positive_regulation of CDK5 1 0.36 0.38 0.1
43 INT64966 Binding of AGFG1 and Cd24 1 0.00 0.1 0.1
44 INT328413 Binding of Snca and Nlrp1a 1 0.06 0.75 0.1
45 INT273236 Cdk5 Positive_regulation of Car2 1 0.13 0.45 0.1
46 INT221959 Binding of CDK5 and CDK5R1 1 0.28 0.53 0.1
47 INT201751 Car2 Positive_regulation of Cdk5 1 0.00 0.67 0.09
48 INT221954 Binding of CDK5 and CDK5R2 1 0.02 0.36 0.09
49 INT83270 Snca Regulation of Napepld 1 0.14 0 0.09
50 INT247948 Positive_regulation of Cdk5r1 Positive_regulation of Cdk5 1 0.26 0.16 0.07
51 INT332329 Binding of Cdk5 and P2rx3 1 0.22 0.05 0.05
52 INT332331 Binding of Cdk5 and Rbm39 1 0.00 0.05 0.05
53 INT326830 Cdk5r1 Positive_regulation of Positive_regulation of Cdk5 1 0.09 0.16 0.04
54 INT221639 Fyn Positive_regulation of Phosphorylation of Cdk5 1 0.14 0.28 0.03
55 INT221661 Sema3a Positive_regulation of Phosphorylation of Cdk5 1 0.19 0.28 0.03
56 INT332330 Cdk5 Negative_regulation of Pirt 1 0.00 0 0.03
57 INT219352 CDK5 Negative_regulation of PAK1 1 0.22 0.72 0.03
58 INT221613 Binding of Cdk5 and Fyn 1 0.10 0.29 0.03
59 INT221617 Fyn Positive_regulation of Cdk5 1 0.13 0.28 0.03
60 INT337677 Scrib Positive_regulation of Gene_expression of MMP9 1 0.03 1.12 0
61 INT307804 Ace Positive_regulation of Gene_expression of Scrib 1 0.21 2.43 0
62 INT317313 Atp13a2 Negative_regulation of Snca 1 0.13 0.59 0
63 INT326162 Binding of ABHD2 and Scrib 1 0.00 1.07 0
64 INT289301 Binding of CD59 and Cd24a 1 0.02 1.06 0
65 INT201734 Binding of Akt1 and Cdk5 1 0.01 0.31 0
66 INT201738 Positive_regulation of Binding of Akt1 and Cdk5 1 0.01 0.31 0
67 INT337680 Binding of TP53 and Scrib 1 0.03 1.6 0
68 INT317315 Gene_expression of Snca Negative_regulation of Psmb10 1 0.00 0.52 0
69 INT317320 Binding of Snca and Atp13a2 1 0.08 0.58 0
70 INT274623 Binding of TRIP10 and Amph 1 0.17 0 0
71 INT337678 Scrib Positive_regulation of MMP7 1 0.03 1.11 0
72 INT337681 Scrib Positive_regulation of MMP9 1 0.01 1.12 0
73 INT326165 Binding of ABHD12 and Scrib 1 0.00 1.01 0
74 INT326164 Binding of S100A2 and Scrib 1 0.01 1.16 0
75 INT337679 Binding of MSI1 and Scrib 1 0.00 1.61 0
76 INT274622 Binding of CLIP1 and Amph 1 0.40 0 0
77 INT201731 Negative_regulation of Binding of Akt1 and Cdk5 1 0.01 0.31 0
78 INT268446 Cdk5 Positive_regulation of Cdk5r1 1 0.02 0.58 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for synaptic vesicle endocytosis. They are ordered first by their pain relevance and then by number of times they were reported in synaptic vesicle endocytosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT123593 Gene_expression of Snca 58 0.78 35.76 12.87
2 INT109223 Negative_regulation of Cdk5 14 0.59 3.27 12.73
3 INT127123 Positive_regulation of Snca 35 0.70 14.76 10.1
4 INT101602 Positive_regulation of Cdk5 15 0.70 4.1 8.96
5 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45
6 INT157580 Phosphorylation of Cdk5 4 0.77 0.73 8.33
7 INT127556 Positive_regulation of Cdk5 35 0.70 19.6 5.95
8 INT101604 Regulation of Cdk5 10 0.61 2.2 5.53
9 INT123594 Negative_regulation of Snca 19 0.59 4.43 4.59
10 INT127122 Positive_regulation of Gene_expression of Snca 11 0.69 15.36 4.56
11 INT148495 Regulation of Cdk5 6 0.58 5.42 3.95
12 INT119412 Gene_expression of Snca 15 0.66 11.27 3.39
13 INT111482 Gene_expression of Cd24a 23 0.72 13.74 3.37
14 INT110245 Gene_expression of SNCA 11 0.77 8.29 3.36
15 INT123595 Regulation of Snca 7 0.62 4.3 3.06
16 INT52256 Negative_regulation of Amph 3 0.38 0.42 2.94
17 INT32675 Regulation of Amph 3 0.39 0.45 2.9
18 INT134795 Positive_regulation of Scrib 30 0.22 36.91 2.81
19 INT93918 Localization of Amph 2 0.62 0.89 2.73
20 INT145328 Negative_regulation of Scrib 25 0.16 26.79 2.66
21 INT196733 Gene_expression of Cdk5 25 0.76 18.25 2.64
22 INT138789 Gene_expression of Cdk5 6 0.76 5.19 2.62
23 INT69147 Localization of AMPH 4 0.61 0 2.44
24 INT32676 Positive_regulation of Amph 4 0.50 0.38 2.36
25 INT148494 Binding of Cdk5 6 0.40 5.97 2.31
26 INT112905 Phosphorylation of Cdk5 15 0.82 2.78 2.3
27 INT52253 Gene_expression of Amph 4 0.49 0.36 2.2
28 INT157579 Binding of Cdk5 3 0.35 0.47 2.13
29 INT127124 Regulation of Gene_expression of Snca 2 0.62 0.17 2.03
30 INT127125 Localization of Snca 6 0.81 8.24 1.88
31 INT148492 Positive_regulation of Binding of Cdk5 1 0.47 0.51 1.86
32 INT158710 Negative_regulation of Binding of Cdk5 1 0.40 0 1.84
33 INT148266 Positive_regulation of SNCA 5 0.67 3.17 1.74
34 INT214351 Regulation of Localization of Amph 1 0.30 0 1.56
35 INT201271 Phosphorylation of Snca 3 0.82 4.22 1.45
36 INT108325 Gene_expression of Scrib 26 0.39 48.33 1.39
37 INT124247 Negative_regulation of Gene_expression of Snca 12 0.59 3.87 1.39
38 INT109222 Positive_regulation of Negative_regulation of Cdk5 2 0.50 0.23 1.39
39 INT158709 Negative_regulation of Phosphorylation of Cdk5 1 0.40 0 1.39
40 INT62130 Positive_regulation of AMPH 3 0.43 0.09 1.35
41 INT10699 Binding of Amph 2 0.31 0.15 1.35
42 INT110244 Positive_regulation of Gene_expression of SNCA 5 0.69 4.66 1.19
43 INT151753 Transcription of Snca 6 0.69 1.99 1.11
44 INT292945 Positive_regulation of Positive_regulation of Snca 4 0.69 2.42 1.05
45 INT273221 Positive_regulation of Negative_regulation of Cdk5 8 0.49 9.89 1.03
46 INT286344 Positive_regulation of Gene_expression of Snca 1 0.41 2.84 1.03
47 INT190031 Binding of Scrib 19 0.36 21.9 1.01
48 INT203893 Positive_regulation of Gene_expression of Cdk5 2 0.49 7.12 0.92
49 INT151752 Positive_regulation of Transcription of Snca 2 0.50 0.99 0.92
50 INT138788 Positive_regulation of Gene_expression of Cdk5 1 0.49 0.44 0.91
51 INT124246 Binding of Snca 10 0.37 6.53 0.9
52 INT127452 Positive_regulation of CDK5 5 0.32 1.88 0.87
53 INT203892 Positive_regulation of Positive_regulation of Cdk5 4 0.49 4.02 0.85
54 INT69148 Positive_regulation of Localization of AMPH 1 0.40 0 0.84
55 INT69149 Positive_regulation of Positive_regulation of AMPH 1 0.43 0 0.82
56 INT219358 Gene_expression of CDK5 9 0.58 5.65 0.81
57 INT138787 Positive_regulation of Positive_regulation of Cdk5 1 0.49 0.38 0.81
58 INT340843 Binding of Cd24a 1 0.02 0.24 0.8
59 INT109954 Regulation of Amph 2 0.22 1.54 0.68
60 INT196790 Localization of Cdk5 6 0.74 2.6 0.67
61 INT266863 Gene_expression of Amph 1 0.49 1.03 0.6
62 INT127557 Positive_regulation of Phosphorylation of Cdk5 2 0.50 0.43 0.56
63 INT109953 Negative_regulation of Amph 1 0.36 0.06 0.54
64 INT340842 Regulation of Gene_expression of Cd24a 1 0.42 0.08 0.53
65 INT64961 Binding of Cd24 4 0.15 0.64 0.5
66 INT326696 Regulation of Cd24a 2 0.44 0 0.48
67 INT32678 Negative_regulation of Regulation of Amph 1 0.37 0 0.47
68 INT214067 Regulation of Scrib 11 0.20 12.48 0.45
69 INT148264 Transcription of SNCA 1 0.40 0.25 0.42
70 INT343972 Negative_regulation of Binding of SNCA 1 0.36 0.2 0.39
71 INT190017 Localization of Scrib 6 0.10 7 0.38
72 INT273218 Negative_regulation of Negative_regulation of Cdk5 1 0.42 3.06 0.37
73 INT108326 Positive_regulation of Gene_expression of Scrib 5 0.26 9.02 0.36
74 INT221973 Negative_regulation of CDK5 4 0.57 2.26 0.36
75 INT169628 Binding of SNCA 4 0.47 3.53 0.36
76 INT214361 Negative_regulation of Gene_expression of Amph 1 0.28 0.09 0.35
77 INT267831 Negative_regulation of Positive_regulation of Scrib 1 0.04 1.56 0.31
78 INT343973 Localization of SNCA 1 0.63 0.07 0.3
79 INT326820 Negative_regulation of Positive_regulation of Cdk5 1 0.36 1.27 0.28
80 INT298972 Transcription of Cdk5 1 0.15 1.63 0.28
81 INT191326 Regulation of AMPH 1 0.19 0 0.27
82 INT164788 Regulation of Gene_expression of Cdk5 1 0.27 0.31 0.24
83 INT142052 Binding of Snca 4 0.47 1.02 0.22
84 INT266867 Localization of Amph 1 0.54 0.34 0.21
85 INT214363 Negative_regulation of Localization of Amph 1 0.28 0.17 0.21
86 INT292944 Regulation of Positive_regulation of Snca 1 0.45 0.36 0.21
87 INT219375 Localization of CDK5 4 0.52 2.8 0.19
88 INT267829 Regulation of Gene_expression of Scrib 2 0.20 5.89 0.19
89 INT267830 Regulation of Negative_regulation of Scrib 1 0.04 0.95 0.19
90 INT221974 Phosphorylation of CDK5 1 0.56 0.99 0.19
91 INT257418 Negative_regulation of Transcription of Snca 1 0.43 0.93 0.19
92 INT273226 Negative_regulation of Gene_expression of Cdk5 2 0.42 0.79 0.17
93 INT166361 Phosphorylation of SNCA 1 0.70 0.72 0.17
94 INT157582 Regulation of Phosphorylation of Cdk5 1 0.26 0.25 0.16
95 INT157084 Localization of Snca 1 0.51 0.17 0.16
96 INT221972 Regulation of CDK5 1 0.42 1.87 0.16
97 INT343974 Negative_regulation of Gene_expression of SNCA 1 0.31 0.09 0.16
98 INT319289 Protein_catabolism of Snca 1 0.35 0.93 0.15
99 INT286343 Negative_regulation of Gene_expression of Snca 1 0.26 0.65 0.15
100 INT253320 Positive_regulation of Positive_regulation of Scrib 1 0.05 0.4 0.14
101 INT266865 Negative_regulation of Regulation of Amph 1 0.31 0.56 0.12
102 INT326822 Negative_regulation of Phosphorylation of Cdk5 1 0.36 0.43 0.12
103 INT341559 Positive_regulation of Gene_expression of CDK5 1 0.23 0.25 0.11
104 INT288642 Negative_regulation of Positive_regulation of Snca 1 0.07 0.93 0.09
105 INT254742 Gene_expression of Cd24 1 0.11 0.46 0.09
106 INT253323 Negative_regulation of Binding of Scrib 1 0.05 0.82 0.09
107 INT201655 Negative_regulation of Binding of Cdk5 1 0.06 0.9 0.09
108 INT254732 Localization of Cd24 1 0.12 0.46 0.09
109 INT355318 Positive_regulation of Gene_expression of Cd24a 1 0.47 1.17 0.09
110 INT341567 Negative_regulation of Gene_expression of CDK5 1 0.27 0.24 0.07
111 INT254740 Negative_regulation of Cd24 1 0.07 0.08 0.07
112 INT296753 Protein_catabolism of Scrib 1 0.05 0.73 0.07
113 INT219355 Binding of CDK5 3 0.35 2.02 0.06
114 INT322866 Binding of AMPH 1 0.05 0.09 0.06
115 INT292946 Positive_regulation of Localization of Snca 1 0.50 0.52 0.06
116 INT326709 Negative_regulation of Gene_expression of Cd24a 3 0.40 0.86 0
117 INT299068 Gene_expression of AMPH 3 0.65 0.08 0
118 INT200854 Transcription of Cd24a 2 0.66 0.4 0
119 INT313331 Transcription of AMPH 1 0.13 0 0
120 INT317275 Positive_regulation of Binding of Snca 1 0.37 0.53 0
121 INT190036 Positive_regulation of Localization of Scrib 1 0.04 0.83 0
122 INT355323 Negative_regulation of Cd24a 1 0.40 0.08 0
123 INT274549 Positive_regulation of Amph 1 0.49 0 0
124 INT307791 Negative_regulation of Gene_expression of Scrib 1 0.19 2.55 0
125 INT268444 Regulation of Positive_regulation of Cdk5 1 0.08 0.66 0
126 INT299067 Negative_regulation of Gene_expression of AMPH 1 0.41 0 0
127 INT343971 Positive_regulation of Positive_regulation of SNCA 1 0.42 0.35 0
128 INT274551 Binding of Amph 1 0.36 0 0
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