GO:0048536

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Name spleen development
Categary Process
Go Slim No
Go Link GO:0048536
Unique Molecular Interactions 571
Total Molecular Interactions 776
Total Single Events 6984
Pain Genes Associated 31

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for spleen development. They are ordered first by their pain relevance and then by number of times they were reported for spleen development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT139190 Binding of Fadd and Fas 4 0.38 2.65 1.71
2 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
3 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
4 INT89878 Pdyn Positive_regulation of Gene_expression of Nkx2-5 1 0.35 0 1.29
5 INT274948 Binding of Dh and Ltp 1 0.11 0.55 1.23
6 INT139191 Binding of Fas and RFFL 1 0.00 0.61 1.22
7 INT281373 Tcf21 Regulation of Fig4 1 0.03 0.67 1.2
8 INT281379 Tcf21 Regulation of FSCN1 1 0.01 0.66 1.19
9 INT139188 Binding of Daxx and Fas 1 0.03 0.55 1.14
10 INT91813 Binding of FAS and FASLG 4 0.23 9.89 0.99
11 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
12 INT316128 TCF21 Negative_regulation of Gene_expression of HLA-DRA 1 0.07 0.13 0.99
13 INT152490 Slc40a1 Negative_regulation of Faah 1 0.01 0.73 0.98
14 INT133617 Fas Positive_regulation of Fadd 1 0.48 0.07 0.96
15 INT22726 Positive_regulation of Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
16 INT22725 Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
17 INT153685 Binding of Bcl2l11 and Gtpbp4 1 0.08 0.76 0.93
18 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
19 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
20 INT130769 FASLG Negative_regulation of Binding of FAS 1 0.10 0.66 0.86
21 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
22 INT117341 ADAM17 Positive_regulation of EGFR 1 0.16 3.56 0.82
23 INT158684 MAPK8 Positive_regulation of Gene_expression of BCL2L11 1 0.51 0.44 0.78
24 INT102162 Binding of TNF and Adam17 1 0.14 0.88 0.78
25 INT316544 BCL2L11 Regulation of INS 1 0.00 1.36 0.77
26 INT102159 Binding of Adam17 and Mmp2 1 0.18 0.87 0.77
27 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
28 INT228499 Binding of FAS and Fasl 1 0.15 2.75 0.73
29 INT101675 Bcl2l11 Regulation of Localization of Ggh 1 0.03 0 0.72
30 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
31 INT104301 Adam17 Regulation of Negative_regulation of Sell 1 0.39 0.58 0.69
32 INT303691 KNG1 Positive_regulation of AHR 1 0.03 0.98 0.69
33 INT303689 Regulation of KNG1 Positive_regulation of AHR 1 0.03 0.99 0.69
34 INT81631 Selenbp2 Negative_regulation of Fas 1 0.03 0.77 0.67
35 INT81630 Selenbp2 Negative_regulation of Positive_regulation of Fas 1 0.03 0.77 0.67
36 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
37 INT89877 Pdyn Positive_regulation of Nkx2-5 1 0.11 0 0.64
38 INT115592 IRF6 Positive_regulation of Gene_expression of FAS 1 0.34 0.34 0.62
39 INT139192 RFFL Positive_regulation of Fas 1 0.00 0.3 0.61
40 INT224419 Binding of NFKB2 and TNFRSF11B 1 0.11 1.37 0.6
41 INT224420 Regulation of Binding of NFKB2 and TNFRSF11B 1 0.13 1.39 0.6
42 INT208372 Il13 Positive_regulation of Ahr 1 0.21 1.22 0.59
43 INT80030 Binding of FAS and TNF 3 0.27 2.54 0.56
44 INT222246 Binding of Ccr2 and Tcf21 1 0.29 0.67 0.55
45 INT160780 Cps1 Positive_regulation of Positive_regulation of FAS 1 0.01 1 0.55
46 INT222249 Positive_regulation of Binding of Ccr2 and Tcf21 1 0.39 0.67 0.55
47 INT147575 Binding of Ahr and Cyp1a1 2 0.15 0.15 0.54
48 INT281124 Tcf21 Positive_regulation of Binding of Ddc 1 0.04 1.21 0.54
49 INT281129 Tcf21 Positive_regulation of Binding of Cd4 1 0.04 1.21 0.54
50 INT281152 Tcf21 Positive_regulation of Binding of ITIH4 1 0.03 1.21 0.54
51 INT55445 Positive_regulation of Ahr Regulation of Mme 1 0.23 0 0.53
52 INT281131 Tcf21 Positive_regulation of Rent1 1 0.00 1.19 0.53
53 INT147576 Positive_regulation of Ahr Positive_regulation of Gene_expression of Scrg1 1 0.00 0.17 0.52
54 INT330544 Bcl2l11 Negative_regulation of Prkcg 1 0.03 0.38 0.52
55 INT330553 Bcl2l11 Negative_regulation of Camk2a 1 0.01 0.38 0.52
56 INT330541 Bcl2l11 Negative_regulation of Negative_regulation of Prkcg 1 0.03 0.38 0.52
57 INT330545 Bcl2l11 Negative_regulation of Trib3 1 0.00 0.38 0.52
58 INT191947 NFKB2 Positive_regulation of Gene_expression of NOS2 1 0.08 1.51 0.52
59 INT162500 AHR Regulation of CYP1A1 3 0.19 0.18 0.51
60 INT281374 Tcf21 Positive_regulation of Gene_expression of Sds 1 0.03 0 0.51
61 INT162503 AHR Regulation of CYP1A2 3 0.61 0.18 0.5
62 INT292873 Binding of Fas and Fasl 5 0.26 15.74 0.49
63 INT162499 Binding of AHR and NEUROD1 3 0.25 0.19 0.49
64 INT158599 Tlr3 Positive_regulation of Binding of Fas 1 0.55 0.86 0.48
65 INT302839 MIR15A Negative_regulation of Bcl2 1 0.15 1.41 0.47
66 INT191950 NFKB2 Regulation of Gene_expression of NOS2 1 0.08 1 0.47
67 INT238639 Cd86 Negative_regulation of Negative_regulation of Bcl2 1 0.01 0.97 0.46
68 INT112772 Binding of Bcl2 and SGSM3 1 0.02 0.69 0.45
69 INT115914 AHR Regulation of Gene_expression of PPIG 1 0.25 0.36 0.44
70 INT115916 AHR Regulation of Gene_expression of SLC45A2 1 0.64 0.36 0.44
71 INT116609 Lnpep Negative_regulation of Bcl2 1 0.05 0.62 0.43
72 INT116606 Lnpep Regulation of Gene_expression of Bcl2 1 0.07 0.62 0.43
73 INT115915 AHR Regulation of Gene_expression of CYP2B6 1 0.06 0.36 0.43
74 INT116607 Lnpep Negative_regulation of Gene_expression of Bcl2 1 0.10 0.62 0.43
75 INT309143 Dlat Positive_regulation of Bcl2 1 0.06 1.04 0.42
76 INT309152 Dlat Positive_regulation of Gene_expression of Bcl2 1 0.04 1.05 0.42
77 INT330519 Binding of CD8A and DICER1 1 0.08 0.99 0.38
78 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
79 INT355018 Binding of FAS and Faslg 1 0.12 1.34 0.37
80 INT60817 Binding of Sstr1 and Bcl2l11 1 0.06 0 0.37
81 INT155062 Csf2 Positive_regulation of Transcription of Bcl2 1 0.31 2.91 0.36
82 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35
83 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34
84 INT155060 Stat3 Negative_regulation of Bcl2 1 0.21 3.7 0.33
85 INT344748 NFKB2 Regulation of Gene_expression of GAD1 1 0.07 0.87 0.33
86 INT222976 NFKBIB Negative_regulation of NFKB2 1 0.01 1.58 0.32
87 INT222251 Negative_regulation of Binding of Cxcl10 and Tcf21 1 0.23 0.34 0.32
88 INT222247 Binding of Cxcl10 and Tcf21 1 0.20 0.34 0.32
89 INT104932 AHR Positive_regulation of CYP1A1 1 0.43 0.83 0.31
90 INT191949 NFKB2 Positive_regulation of NOS2 1 0.05 1.16 0.31
91 INT332972 Fas Positive_regulation of Ppara 1 0.17 0.52 0.31
92 INT80029 Binding of FAS and Positive_regulation of NFKB1 1 0.34 0.92 0.3
93 INT224422 Regulation of Binding of NFKB2 and TNFSF11 1 0.13 0.69 0.3
94 INT242398 Cyp19a1 Positive_regulation of Bcl2 1 0.00 1.28 0.3
95 INT281127 Tcf21 Positive_regulation of Gene_expression of Cxcr4 1 0.08 0.42 0.3
96 INT224418 Binding of NFKB2 and TNFSF11 1 0.11 0.68 0.3
97 INT80031 FAS Positive_regulation of Positive_regulation of NFKB1 1 0.50 0.93 0.3
98 INT109067 Pdyn Positive_regulation of Gene_expression of NKX2-5 1 0.01 0 0.29
99 INT239336 Nr1h2 Positive_regulation of Gene_expression of Fas 1 0.07 0.84 0.29
100 INT228500 Fadd Positive_regulation of FAS 1 0.14 1.12 0.28
101 INT218928 Cyp3a23/3a1 Regulation of Transcription of Bcl2 1 0.00 0.56 0.28
102 INT260837 NRP2 Negative_regulation of Negative_regulation of Bcl2 1 0.00 0.9 0.28
103 INT172905 Binding of Bad and Bcl2 3 0.08 6.46 0.27
104 INT93352 Ifng Positive_regulation of Positive_regulation of Fas 1 0.26 0.17 0.27
105 INT237927 BCL2 Positive_regulation of BAX 2 0.24 2.22 0.26
106 INT237928 BCL2 Positive_regulation of FAS 1 0.02 1.41 0.26
107 INT272157 Gh1 Negative_regulation of Bcl2 1 0.23 1.2 0.26
108 INT272158 Gh1 Regulation of Bcl2 1 0.15 1.2 0.26
109 INT237925 BCL2 Positive_regulation of Protein_catabolism of PARP1 1 0.02 1.42 0.26
110 INT235013 Binding of DSG1 and Adam17 1 0.07 1.34 0.26
111 INT234980 Positive_regulation of Egfr Positive_regulation of Adam17 1 0.09 1.33 0.26
112 INT149713 Binding of Casp3 and Fas 1 0.40 1.09 0.25
113 INT260840 NRP2 Positive_regulation of Gene_expression of Bcl2 1 0.00 0.85 0.24
114 INT279959 Tnfrsf1b Negative_regulation of Ahr 1 0.10 0.98 0.24
115 INT171049 Binding of FAS and Positive_regulation of Gene_expression of CASP3 1 0.04 1.41 0.24
116 INT221416 Binding of IL1B and Positive_regulation of NFKB2 1 0.02 0.88 0.23
117 INT179186 Fcer2a Regulation of Positive_regulation of Ahr 1 0.05 1.23 0.23
118 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23
119 INT88023 Tnf Negative_regulation of Gene_expression of Fas 1 0.29 0.74 0.22
120 INT88025 Ifng Negative_regulation of Gene_expression of Fas 1 0.32 0.74 0.22
121 INT148533 Binding of Alb and Fas 1 0.23 0.08 0.21
122 INT343849 Binding of FAS and TLR4 1 0.04 0.32 0.21
123 INT269994 Binding of Nfkb2 and Tpx2 1 0.04 0.51 0.21
124 INT330051 Mapk8 Positive_regulation of Bcl2l11 1 0.13 0.46 0.21
125 INT269995 Positive_regulation of Binding of Nfkb2 and Tpx2 1 0.05 0.51 0.21
126 INT304104 Il13 Positive_regulation of Positive_regulation of AHR 1 0.14 2.6 0.19
127 INT188921 Binding of Pc and Ahr 1 0.12 0 0.19
128 INT188920 Pc Positive_regulation of Ahr 1 0.14 0 0.18
129 INT176133 AKT1 Regulation of BCL2 2 0.12 1.84 0.17
130 INT229223 Binding of AGT and FAS 1 0.08 0.91 0.17
131 INT285026 Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
132 INT285022 Regulation of Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
133 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17
134 INT155233 TXNIP Regulation of BCL2 1 0.23 0.15 0.17
135 INT285024 Bcl2 Regulation of Bak1 1 0.09 0.71 0.17
136 INT229245 Positive_regulation of Binding of FAS and Tnf 1 0.25 0.92 0.17
137 INT229203 Binding of Bcl2 and Cyp2c11 1 0.36 1.2 0.17
138 INT155068 Csf2 Negative_regulation of Bcl2 1 0.12 1.88 0.17
139 INT229246 Binding of FAS and Tnf 1 0.19 0.91 0.17
140 INT229224 Positive_regulation of Binding of AGT and FAS 1 0.09 0.92 0.17
141 INT175328 FASLG Positive_regulation of FAS 1 0.01 0.9 0.17
142 INT347445 CD99 Positive_regulation of BCL2 1 0.17 0.95 0.16
143 INT91811 Binding of FAS and TP53 1 0.21 1.1 0.16
144 INT332968 Hoxb4 Positive_regulation of Ppara 1 0.02 0.25 0.16
145 INT171871 Binding of FAS and Sumo1 1 0.02 1.43 0.16
146 INT134196 Ahr Regulation of Transcription of Cyp1a1 1 0.11 0.14 0.16
147 INT134202 Ahr Regulation of AHR 1 0.18 0.13 0.16
148 INT292750 Akt1 Positive_regulation of Bcl2 1 0.01 1.67 0.15
149 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15
150 INT333241 Cxcl12 Regulation of Bcl2l11 1 0.18 1.11 0.15
151 INT153785 AHR Regulation of UGT1A3 1 0.69 0.07 0.14
152 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
153 INT36376 Binding of AHR and FUT4 1 0.01 0.9 0.14
154 INT304094 Binding of AHR and SNRNP70 1 0.00 2.64 0.14
155 INT350711 Ifnb1 Negative_regulation of Gene_expression of DICER1 1 0.03 0.15 0.14
156 INT95104 TGFBR2 Positive_regulation of BCL2 1 0.08 0.61 0.14
157 INT309139 Edc4 Positive_regulation of Bcl2 1 0.03 0.12 0.13
158 INT332966 Binding of Fas and Ppara 1 0.15 0.25 0.13
159 INT148594 Binding of BCL2 and CD34 1 0.39 1.17 0.13
160 INT353897 Negative_regulation of Prkcg Negative_regulation of Localization of Bcl2l11 1 0.08 0.4 0.13
161 INT309142 Edc4 Regulation of Bcl2 1 0.02 0.12 0.13
162 INT246016 Negative_regulation of Timp1 Negative_regulation of Gene_expression of Bcl2 1 0.03 1.07 0.13
163 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
164 INT348542 BCL2 Negative_regulation of NLRP1 1 0.07 2.02 0.13
165 INT338419 Il13 Regulation of Positive_regulation of Ahr 1 0.04 0.54 0.13
166 INT246017 Timp1 Negative_regulation of Gene_expression of Bcl2 1 0.03 1.07 0.13
167 INT172899 Binding of Bcl2 and Bcl2l1 3 0.02 5.54 0.12
168 INT178101 EDN1 Negative_regulation of Phosphorylation of BCL2 1 0.03 1 0.12
169 INT305194 Bcl2 Positive_regulation of Epo 1 0.06 0.29 0.12
170 INT91455 IL1B Positive_regulation of Phosphorylation of NFKB2 1 0.05 0.47 0.12
171 INT318993 Hand1 Positive_regulation of Gene_expression of Fas 1 0.03 0.76 0.12
172 INT36373 Binding of AHR and INSL3 1 0.00 0.5 0.12
173 INT318995 IFN1@ Positive_regulation of Gene_expression of Fas 1 0.23 0.76 0.12
174 INT91458 IL1B Positive_regulation of Positive_regulation of NFKB2 1 0.08 0.47 0.12
175 INT273063 Negative_regulation of Fas Negative_regulation of Positive_regulation of Bcl2 1 0.01 0.72 0.11
176 INT259629 Binding of Adam17 and Timp3 1 0.01 0.19 0.11
177 INT336632 Ecm1 Regulation of Regulation of Ahr 1 0.03 0.61 0.11
178 INT143648 Negative_regulation of Mapk8 Negative_regulation of Gene_expression of Fas 1 0.39 0.21 0.11
179 INT221684 Binding of Bcl2 and FRTS 1 0.01 1.19 0.11
180 INT325222 Il13 Regulation of Ahr 1 0.21 0.58 0.11
181 INT299015 Binding of FAS and Il18 1 0.38 0.83 0.11
182 INT265888 BCL2 Regulation of Gene_expression of BAD 1 0.04 1.08 0.1
183 INT265890 BCL2 Regulation of Gene_expression of BAX 1 0.04 1.08 0.1
184 INT208938 Positive_regulation of Tacr1 Positive_regulation of Nkx2-5 1 0.17 0 0.1
185 INT227061 Binding of Ahr and Alb 1 0.23 0.08 0.1
186 INT333242 Bcl2l11 Positive_regulation of Gene_expression of Cxcl12 1 0.18 1.48 0.1
187 INT134201 Positive_regulation of Binding of AHR and Cyp1a1 1 0.21 0.07 0.1
188 INT134200 Binding of AHR and Cyp1a1 1 0.16 0.07 0.1
189 INT239643 Binding of BCL2 and BCL2L11 3 0.16 2.26 0.09
190 INT282094 Apoa2 Negative_regulation of BCL2 1 0.06 1.15 0.09
191 INT275183 Bad Positive_regulation of Gene_expression of Bcl2 1 0.08 0.63 0.09
192 INT265887 IGF1 Negative_regulation of BCL2 1 0.09 1.02 0.09
193 INT277091 VEGFA Positive_regulation of Fas 1 0.03 1.72 0.09
194 INT294637 Bcl2a1a Positive_regulation of Gene_expression of Bcl2 1 0.15 0.97 0.09
195 INT204300 Bcl2 Negative_regulation of Positive_regulation of Bak1 1 0.02 1.13 0.09
196 INT263450 NFKB2 Positive_regulation of Protein_catabolism of NFKBIA 1 0.17 0.17 0.09
197 INT137252 BCL2L11 Regulation of NCAM1 1 0.20 0.99 0.08
198 INT303124 Binding of Fas and Tnfrsf10b 1 0.09 1.03 0.08
199 INT333251 Binding of Bcl2l11 and Cxcl12 1 0.14 1.74 0.08
200 INT137254 BCL2L11 Regulation of VIM 1 0.17 0.99 0.08

Single Events

The table below shows the top 100 pain related interactions that have been reported for spleen development. They are ordered first by their pain relevance and then by number of times they were reported in spleen development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
2 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
3 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
4 INT70614 Gene_expression of FAS 118 0.75 112.33 19.01
5 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
6 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
7 INT77620 Gene_expression of Fas 146 0.78 72.4 16.61
8 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36
9 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
10 INT81629 Positive_regulation of Fas 58 0.70 59.63 12.94
11 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
12 INT88020 Positive_regulation of Fas 32 0.70 19.78 9.97
13 INT215353 Gene_expression of Tcf21 16 0.59 9.71 9.49
14 INT80036 Positive_regulation of FAS 42 0.67 42.22 9.4
15 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
16 INT80034 Positive_regulation of Gene_expression of FAS 32 0.67 30.34 8.51
17 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
18 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
19 INT65803 Gene_expression of Dh 10 0.32 1.24 8.07
20 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
21 INT90603 Positive_regulation of Ahr 103 0.69 58.65 7.73
22 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
23 INT14166 Positive_regulation of Ahr 32 0.61 20.78 7.47
24 INT88014 Positive_regulation of Gene_expression of Fas 29 0.50 14.84 7.47
25 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
26 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
27 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
28 INT130875 Gene_expression of ADAM17 13 0.78 15.46 6.41
29 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7
30 INT80033 Binding of FAS 37 0.48 41.19 5.67
31 INT113516 Negative_regulation of Fas 16 0.51 8.37 5.32
32 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22
33 INT59723 Binding of Slc40a1 5 0.35 1.31 5.17
34 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07
35 INT54002 Negative_regulation of Dh 6 0.20 3.05 5.06
36 INT72834 Negative_regulation of Tcf21 10 0.58 5.8 4.84
37 INT113517 Binding of Fas 16 0.37 15.86 4.62
38 INT91463 Positive_regulation of NFKB2 19 0.40 17.7 4.6
39 INT149197 Negative_regulation of NFKB2 14 0.25 10.55 4.46
40 INT104299 Negative_regulation of Adam17 18 0.47 12.03 4.39
41 INT89963 Regulation of Fas 15 0.59 8.25 4.32
42 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3
43 INT81628 Positive_regulation of Gene_expression of Fas 32 0.67 38.13 4.23
44 INT14165 Negative_regulation of Ahr 14 0.51 8.35 4.17
45 INT115889 Binding of Fas 27 0.36 28.87 4.08
46 INT22566 Positive_regulation of Tcf21 8 0.65 3.06 3.75
47 INT105882 Phosphorylation of Bcl2 11 0.59 8.15 3.73
48 INT115921 Positive_regulation of AHR 22 0.49 12.03 3.53
49 INT89966 Negative_regulation of Fas 26 0.58 24.83 3.5
50 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4
51 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19
52 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16
53 INT147572 Gene_expression of Ahr 73 0.75 38.99 3.15
54 INT47207 Negative_regulation of Ahr 25 0.52 16.11 3.02
55 INT105884 Binding of Bcl2 19 0.35 15.67 3
56 INT281367 Regulation of Gene_expression of Tcf21 1 0.09 1.39 2.89
57 INT102157 Gene_expression of Adam17 3 0.58 4.17 2.86
58 INT44661 Regulation of Ahr 15 0.45 12.69 2.79
59 INT49653 Gene_expression of NFKB2 12 0.61 9.51 2.73
60 INT190280 Gene_expression of DICER1 12 0.65 9.54 2.67
61 INT281369 Negative_regulation of Gene_expression of Tcf21 1 0.08 1.4 2.44
62 INT96876 Gene_expression of AHR 20 0.77 10.43 2.39
63 INT147349 Localization of Bcl2 13 0.65 7.83 2.31
64 INT88017 Regulation of Fas 12 0.62 8.27 2.29
65 INT142677 Negative_regulation of Positive_regulation of Bcl2 4 0.36 3.09 2.24
66 INT77621 Regulation of Gene_expression of Fas 10 0.56 7.62 2.08
67 INT98132 Regulation of FAS 16 0.42 20.57 2.06
68 INT102176 Transcription of FAS 3 0.60 3.22 2.05
69 INT86671 Negative_regulation of Positive_regulation of Bcl2 6 0.57 3.83 2.03
70 INT90004 Gene_expression of TCF21 4 0.65 2.48 2.02
71 INT243689 Regulation of NFKB2 1 0.35 2.72 1.97
72 INT228129 Negative_regulation of Bcl2l11 10 0.58 11.08 1.93
73 INT107905 Gene_expression of BCL2L11 9 0.75 7.58 1.92
74 INT113515 Positive_regulation of Positive_regulation of Fas 4 0.69 0.95 1.92
75 INT153684 Negative_regulation of Bcl2l11 3 0.31 1.19 1.89
76 INT101108 Localization of Bcl2 16 0.72 11.68 1.86
77 INT105883 Positive_regulation of Phosphorylation of Bcl2 8 0.32 5.67 1.86
78 INT121784 Regulation of Gene_expression of Fas 7 0.38 5.68 1.86
79 INT117346 Positive_regulation of ADAM17 5 0.50 6.69 1.86
80 INT97750 Positive_regulation of Positive_regulation of FAS 4 0.49 4.9 1.8
81 INT96877 Transcription of AHR 7 0.62 3.25 1.77
82 INT134197 Regulation of AHR 11 0.44 4.82 1.76
83 INT130874 Negative_regulation of Gene_expression of ADAM17 3 0.43 5.03 1.76
84 INT59722 Negative_regulation of Slc40a1 3 0.11 0.56 1.73
85 INT14167 Negative_regulation of Positive_regulation of Ahr 5 0.51 1.54 1.71
86 INT316162 Localization of TCF21 1 0.18 0.28 1.71
87 INT221433 Binding of NFKB2 6 0.11 4.74 1.7
88 INT60815 Binding of Bcl2l11 2 0.27 0.95 1.67
89 INT101958 Positive_regulation of Transcription of Bcl2 4 0.50 2.22 1.65
90 INT137513 Negative_regulation of Positive_regulation of BCL2 6 0.35 5.3 1.62
91 INT132882 Gene_expression of Slc40a1 4 0.17 1.35 1.6
92 INT89865 Gene_expression of Nkx2-5 14 0.75 2.99 1.58
93 INT130332 Gene_expression of Adam17 14 0.50 4.84 1.56
94 INT36389 Binding of AHR 18 0.45 7.22 1.46
95 INT90604 Positive_regulation of Positive_regulation of Ahr 8 0.45 3.52 1.45
96 INT89965 Transcription of Fas 5 0.71 5.28 1.45
97 INT130260 Gene_expression of Nfkb2 7 0.60 3.85 1.43
98 INT54805 Regulation of Ahr 7 0.22 4.14 1.41
99 INT222228 Positive_regulation of Gene_expression of Tcf21 4 0.38 0.84 1.39
100 INT188404 Positive_regulation of Binding of Fas 3 0.15 5.22 1.37
101 INT110485 Binding of Tcf21 2 0.36 0.76 1.37
102 INT130773 Regulation of Gene_expression of FAS 5 0.37 6.87 1.32
103 INT78861 Negative_regulation of Transcription of Adam17 2 0.29 1.4 1.32
104 INT3816 Gene_expression of Ahr 13 0.65 7.51 1.31
105 INT78859 Transcription of Adam17 2 0.47 1.39 1.31
106 INT101107 Positive_regulation of Localization of Bcl2 3 0.48 3.13 1.28
107 INT82345 Regulation of Slc40a1 2 0.23 0.33 1.28
108 INT228128 Gene_expression of Bcl2l11 31 0.67 18.31 1.25
109 INT107904 Positive_regulation of Gene_expression of BCL2L11 3 0.53 2.22 1.24
110 INT29693 Binding of Ahr 11 0.31 13.27 1.23
111 INT115108 Negative_regulation of Gene_expression of FAS 9 0.57 9.16 1.23
112 INT316154 Positive_regulation of TCF21 4 0.17 1.22 1.23
113 INT139183 Regulation of Binding of Fas 3 0.43 2.5 1.23
114 INT234893 Positive_regulation of Adam17 4 0.38 3.78 1.22
115 INT303667 Regulation of BCL2L11 3 0.16 1.03 1.21
116 INT330526 Positive_regulation of Gene_expression of DICER1 5 0.30 3.34 1.18
117 INT89967 Negative_regulation of Gene_expression of Fas 19 0.58 19.28 1.1
118 INT97695 Positive_regulation of Dh 3 0.33 1.44 1.1
119 INT172855 Binding of Bcl2 37 0.32 23.41 1.09
120 INT70021 Localization of BCL2 23 0.74 21.6 1.09
121 INT332771 Phosphorylation of Tcf21 1 0.09 0.21 1.07
122 INT332772 Positive_regulation of Phosphorylation of Tcf21 1 0.06 0.21 1.07
123 INT161716 Localization of Nkx2-5 2 0.74 2.17 1.02
124 INT132435 Negative_regulation of ADAM17 2 0.50 3.75 1.02
125 INT109075 Positive_regulation of Transcription of NKX2-5 1 0.67 0 1.02
126 INT109074 Transcription of NKX2-5 1 0.69 0 1.01
127 INT45079 Binding of Ahr 21 0.44 10.07 1
128 INT161369 Protein_catabolism of FAS 1 0.86 1.23 1
129 INT121785 Regulation of Transcription of Fas 1 0.23 0.73 0.96
130 INT228130 Positive_regulation of Bcl2l11 14 0.49 10 0.9
131 INT112694 Negative_regulation of Positive_regulation of Fas 5 0.42 4.3 0.89
132 INT102677 Negative_regulation of TCF21 2 0.41 0.22 0.89
133 INT94546 Transcription of Fas 13 0.56 6.99 0.88
134 INT151115 Regulation of Regulation of Bcl2 4 0.21 4.12 0.88
135 INT130772 Positive_regulation of Transcription of FAS 1 0.24 0.67 0.87
136 INT312362 Gene_expression of PBX1 1 0.56 4.48 0.87
137 INT92117 Phosphorylation of BCL2 26 0.80 9.93 0.86
138 INT109062 Gene_expression of NKX2-5 7 0.75 3.31 0.82
139 INT312364 Positive_regulation of PBX1 1 0.43 4.69 0.81
140 INT202683 Localization of FAS 6 0.73 5.86 0.8
141 INT95667 Positive_regulation of Nfkb2 3 0.22 3.95 0.8
142 INT70019 Binding of BCL2 25 0.47 17.55 0.79
143 INT143482 Negative_regulation of Gene_expression of Fas 20 0.41 8.3 0.79
144 INT109404 Transcription of BCL2 6 0.69 4.49 0.77
145 INT191952 Negative_regulation of Positive_regulation of NFKB2 4 0.11 3.31 0.76
146 INT124844 Regulation of Positive_regulation of Bcl2 3 0.43 2.55 0.75
147 INT155392 Negative_regulation of Negative_regulation of Bcl2 3 0.21 1.64 0.74
148 INT105947 Binding of Dh 3 0.35 0.79 0.72
149 INT134444 Positive_regulation of Binding of Bcl2 3 0.47 2.67 0.72
150 INT120494 Protein_catabolism of Fas 3 0.88 0.91 0.69
151 INT139180 Regulation of Positive_regulation of Fas 2 0.43 2.19 0.69
152 INT208367 Regulation of Localization of Ahr 1 0.30 1.6 0.67
153 INT208371 Localization of Ahr 2 0.50 1.9 0.66
154 INT94548 Localization of Fas 9 0.77 5.15 0.65
155 INT188403 Positive_regulation of Positive_regulation of Fas 3 0.46 4.47 0.63
156 INT89861 Negative_regulation of Nkx2-5 3 0.19 0.12 0.63
157 INT114942 Negative_regulation of Positive_regulation of Ahr 5 0.55 2.65 0.62
158 INT191951 Negative_regulation of Gene_expression of NFKB2 2 0.24 1.34 0.62
159 INT281366 Regulation of Tcf21 1 0.09 0.23 0.59
160 INT64096 Negative_regulation of AHR 5 0.37 1.2 0.58
161 INT211808 Localization of NFKB2 4 0.19 4.17 0.58
162 INT70025 Positive_regulation of Positive_regulation of BCL2 3 0.27 0.96 0.58
163 INT223462 Binding of Hoxb4 1 0.01 0.08 0.58
164 INT296583 Gene_expression of Fgf10 3 0.59 2.64 0.57
165 INT178128 Negative_regulation of Phosphorylation of BCL2 7 0.27 3.94 0.56
166 INT296594 Regulation of Fgf10 1 0.15 1.53 0.56
167 INT89869 Negative_regulation of Gene_expression of Nkx2-5 1 0.41 0 0.56
168 INT316161 Negative_regulation of Gene_expression of TCF21 1 0.10 0.11 0.56
169 INT138678 Transcription of ADAM17 1 0.69 4.9 0.56
170 INT139181 Positive_regulation of Regulation of Fas 1 0.45 0.25 0.56
171 INT155090 Regulation of Positive_regulation of BCL2 3 0.26 1.78 0.54
172 INT147571 Regulation of Binding of Ahr 1 0.26 0.15 0.54
173 INT104935 Localization of AHR 6 0.74 2.54 0.53
174 INT310908 Positive_regulation of Bcl2l11 2 0.38 2.38 0.53
175 INT221432 Positive_regulation of Binding of NFKB2 2 0.12 1.59 0.53
176 INT186728 Negative_regulation of Positive_regulation of AHR 1 0.08 1.61 0.52
177 INT144696 Regulation of Transcription of Bcl2 5 0.44 2.96 0.51
178 INT138676 Localization of ADAM17 4 0.73 4.91 0.5
179 INT303674 Positive_regulation of Regulation of BCL2L11 1 0.02 0.28 0.5
180 INT134445 Positive_regulation of Positive_regulation of Bcl2 3 0.47 2.43 0.49
181 INT125381 Regulation of Dh 3 0.29 1.07 0.49
182 INT305390 Negative_regulation of NKX2-5 2 0.37 2.24 0.49
183 INT100822 Localization of Fas 8 0.74 6.13 0.48
184 INT158829 Negative_regulation of FAS 5 0.41 4.12 0.48
185 INT221676 Protein_catabolism of Bcl2 4 0.24 2.77 0.48
186 INT218903 Gene_expression of Bcl2l11 10 0.42 5.19 0.45
187 INT204052 Transcription of Bcl2 5 0.51 3.25 0.45
188 INT222229 Localization of Tcf21 1 0.57 0.45 0.45
189 INT140295 Protein_catabolism of BCL2 4 0.64 5.7 0.44
190 INT220424 Positive_regulation of Negative_regulation of Bcl2 2 0.14 1.81 0.44
191 INT94035 Transcription of Ahr 1 0.53 0.53 0.43
192 INT263327 Positive_regulation of Positive_regulation of NFKB2 2 0.08 2.95 0.42
193 INT272502 Transcription of DICER1 3 0.08 2.14 0.39
194 INT251556 Localization of Adam17 2 0.38 2 0.39
195 INT343811 Positive_regulation of Transcription of DICER1 1 0.06 2.06 0.39
196 INT228126 Positive_regulation of Gene_expression of Bcl2l11 9 0.50 6.49 0.37
197 INT155724 Negative_regulation of Transcription of Bcl2 6 0.53 2.35 0.37
198 INT279958 Regulation of Regulation of Ahr 1 0.29 1.32 0.37
199 INT197286 Positive_regulation of Gene_expression of Ahr 10 0.67 9.78 0.36
200 INT135804 Positive_regulation of Negative_regulation of Fas 2 0.56 1.24 0.36
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