GO:0048538

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Name thymus development
Categary Process
Go Slim No
Go Link GO:0048538
Unique Molecular Interactions 742
Total Molecular Interactions 966
Total Single Events 9353
Pain Genes Associated 46

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for thymus development. They are ordered first by their pain relevance and then by number of times they were reported for thymus development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT163266 Crh Negative_regulation of Tyr 1 0.01 0.45 1.98
2 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
3 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
4 INT61443 Binding of KNG1 and Tyr 1 0.00 0 1.46
5 INT104972 MITF Regulation of Transcription of TYR 1 0.20 0.35 1.45
6 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
7 INT42579 SOD1 Negative_regulation of POMC 1 0.16 0.43 1.27
8 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
9 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
10 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
11 INT163265 Sst Negative_regulation of Tyr 1 0.00 0.22 0.95
12 INT153685 Binding of Bcl2l11 and Gtpbp4 1 0.08 0.76 0.93
13 INT141276 Negative_regulation of Il18 Negative_regulation of Gene_expression of Hand2 1 0.25 0.8 0.92
14 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
15 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
16 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
17 INT158684 MAPK8 Positive_regulation of Gene_expression of BCL2L11 1 0.51 0.44 0.78
18 INT316544 BCL2L11 Regulation of INS 1 0.00 1.36 0.77
19 INT161951 Positive_regulation of TGFBR1 Positive_regulation of Gene_expression of Ngf 1 0.27 0.99 0.76
20 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
21 INT37439 Binding of Shbdp1 and Tyr 1 0.01 0 0.76
22 INT250959 Binding of HLA-B and SOD1 1 0.05 0.75 0.75
23 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
24 INT195778 Binding of APC and PROCR 7 0.19 3.78 0.73
25 INT46917 Binding of Tyr and Positive_regulation of Penk 1 0.02 0 0.73
26 INT46919 Binding of Tyr and Positive_regulation of Vom1r1 1 0.00 0 0.73
27 INT161950 TGFBR1 Negative_regulation of Localization of Ngf 1 0.23 1.01 0.72
28 INT101675 Bcl2l11 Regulation of Localization of Ggh 1 0.03 0 0.72
29 INT296097 Acsm3 Negative_regulation of SOD1 1 0.01 1.3 0.72
30 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
31 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69
32 INT99172 Pomc Positive_regulation of Tyr 1 0.35 0.17 0.69
33 INT102762 Binding of POMC and TYR 1 0.12 0.35 0.69
34 INT344387 Efnb2 Positive_regulation of Phosphorylation of Tyr 1 0.01 1.05 0.66
35 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
36 INT99170 Binding of Mc1r and Tyr 1 0.11 0.2 0.64
37 INT83804 Binding of EPHB3 and DRGX 1 0.00 0.62 0.62
38 INT70811 Penk Negative_regulation of Binding of Tyr 1 0.01 0 0.6
39 INT101087 NTF3 Positive_regulation of Gene_expression of IKZF1 1 0.04 0.3 0.55
40 INT160829 Tyr Regulation of RYBP 1 0.04 0.75 0.53
41 INT330544 Bcl2l11 Negative_regulation of Prkcg 1 0.03 0.38 0.52
42 INT330553 Bcl2l11 Negative_regulation of Camk2a 1 0.01 0.38 0.52
43 INT330541 Bcl2l11 Negative_regulation of Negative_regulation of Prkcg 1 0.03 0.38 0.52
44 INT330545 Bcl2l11 Negative_regulation of Trib3 1 0.00 0.38 0.52
45 INT302644 ARSA Positive_regulation of Gene_expression of TGFBR1 1 0.04 0.29 0.51
46 INT302647 ARSA Positive_regulation of TGFBR1 1 0.03 0.29 0.51
47 INT274625 OPN1MW Positive_regulation of SOD1 1 0.19 0.29 0.5
48 INT108692 NTF3 Regulation of Gene_expression of IKZF1 1 0.69 0.7 0.49
49 INT31531 Mif-ps1 Regulation of TYR 1 0.11 0 0.49
50 INT182150 Binding of APC and DCPS 1 0.02 1.14 0.48
51 INT114297 Apc Negative_regulation of Gene_expression of Fcer2a 1 0.03 0.96 0.48
52 INT302839 MIR15A Negative_regulation of Bcl2 1 0.15 1.41 0.47
53 INT338426 Binding of Hand1 and Hand2 2 0.06 2 0.46
54 INT275549 Il10 Positive_regulation of Localization of Hand2 1 0.01 1.3 0.46
55 INT168699 Binding of Nedd4 and Tyr 1 0.02 0.45 0.46
56 INT275550 Hand1 Positive_regulation of Localization of Hand2 1 0.00 1.29 0.46
57 INT238639 Cd86 Negative_regulation of Negative_regulation of Bcl2 1 0.01 0.97 0.46
58 INT112772 Binding of Bcl2 and SGSM3 1 0.02 0.69 0.45
59 INT241914 SOD1 Positive_regulation of Ros1 1 0.00 0.76 0.44
60 INT116609 Lnpep Negative_regulation of Bcl2 1 0.05 0.62 0.43
61 INT116606 Lnpep Regulation of Gene_expression of Bcl2 1 0.07 0.62 0.43
62 INT116607 Lnpep Negative_regulation of Gene_expression of Bcl2 1 0.10 0.62 0.43
63 INT309143 Dlat Positive_regulation of Bcl2 1 0.06 1.04 0.42
64 INT309152 Dlat Positive_regulation of Gene_expression of Bcl2 1 0.04 1.05 0.42
65 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
66 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
67 INT10825 Binding of PDYN and Tyr 1 0.01 0 0.39
68 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
69 INT250956 Positive_regulation of Binding of HLA-B and SOD1 1 0.07 0.38 0.38
70 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
71 INT60817 Binding of Sstr1 and Bcl2l11 1 0.06 0 0.37
72 INT84887 APC Negative_regulation of Gene_expression of PPARD 1 0.36 0.55 0.37
73 INT35685 TYR Regulation of Oxt 1 0.14 0.32 0.36
74 INT155062 Csf2 Positive_regulation of Transcription of Bcl2 1 0.31 2.91 0.36
75 INT99171 Negative_regulation of Pomc Positive_regulation of Tyr 1 0.22 0.08 0.35
76 INT305853 Polk Regulation of Gene_expression of Hand2 1 0.12 0.93 0.35
77 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35
78 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
79 INT300751 Binding of IGHE and Hand2 1 0.04 0 0.34
80 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34
81 INT155060 Stat3 Negative_regulation of Bcl2 1 0.21 3.7 0.33
82 INT266806 Hand2 Regulation of Gene_expression of IL10 1 0.00 1.23 0.32
83 INT241139 Ighg1 Positive_regulation of Hand2 1 0.06 0.65 0.32
84 INT181435 Binding of Ccr2 and Hand2 1 0.17 1.81 0.32
85 INT280926 Hoxa3 Positive_regulation of Gene_expression of Ccl2 1 0.53 2.61 0.32
86 INT195665 APC Negative_regulation of F8 1 0.04 1.53 0.32
87 INT181433 Hand2 Regulation of Gene_expression of Ccl2 1 0.12 0.68 0.32
88 INT242164 Wnt2 Positive_regulation of Localization of Apc 1 0.13 1.53 0.32
89 INT266804 Hand2 Regulation of Gene_expression of IL13 1 0.00 1.23 0.32
90 INT266805 Hand2 Regulation of Gene_expression of IL4 1 0.00 1.23 0.32
91 INT195664 APC Negative_regulation of F5 1 0.08 1.51 0.31
92 INT253073 Il4 Positive_regulation of Hand2 1 0.10 0.59 0.31
93 INT300742 Stat6 Regulation of Hand2 1 0.01 0.06 0.3
94 INT300752 GATA3 Regulation of Hand2 1 0.01 0.06 0.3
95 INT63122 Binding of APC and Man2a2 1 0.01 0.15 0.3
96 INT242398 Cyp19a1 Positive_regulation of Bcl2 1 0.00 1.28 0.3
97 INT93988 Rab8a Regulation of Hand2 1 0.09 0.78 0.3
98 INT181442 Ccl2 Positive_regulation of Localization of Hand2 1 0.26 0.63 0.29
99 INT185076 Bpifa2 Positive_regulation of Hand2 1 0.16 0.36 0.28
100 INT278209 Ciita Regulation of Hand2 1 0.36 1.53 0.28
101 INT218928 Cyp3a23/3a1 Regulation of Transcription of Bcl2 1 0.00 0.56 0.28
102 INT194821 MAPK1 Regulation of Hand2 1 0.03 1.27 0.28
103 INT260837 NRP2 Negative_regulation of Negative_regulation of Bcl2 1 0.00 0.9 0.28
104 INT289954 Binding of APC and CD28 1 0.03 0.38 0.28
105 INT278216 Ciita Regulation of Gene_expression of Hand2 1 0.36 1.53 0.28
106 INT172905 Binding of Bad and Bcl2 3 0.08 6.46 0.27
107 INT246442 Hand2 Positive_regulation of Gene_expression of Cd79a 1 0.03 0.78 0.27
108 INT350813 Binding of Apc and Crp 1 0.18 1.12 0.27
109 INT71640 Binding of HLA-A and TYR 1 0.16 0.36 0.27
110 INT305849 Polk Positive_regulation of Gene_expression of Hand2 1 0.08 0.76 0.27
111 INT237927 BCL2 Positive_regulation of BAX 2 0.24 2.22 0.26
112 INT237928 BCL2 Positive_regulation of FAS 1 0.02 1.41 0.26
113 INT272157 Gh1 Negative_regulation of Bcl2 1 0.23 1.2 0.26
114 INT272158 Gh1 Regulation of Bcl2 1 0.15 1.2 0.26
115 INT311918 Insrr Negative_regulation of Tgfbr1 1 0.00 0.87 0.26
116 INT237925 BCL2 Positive_regulation of Protein_catabolism of PARP1 1 0.02 1.42 0.26
117 INT311902 Acvrl1 Negative_regulation of Tgfbr1 1 0.13 0.87 0.26
118 INT226537 Hand2 Positive_regulation of IL22 1 0.02 0.86 0.26
119 INT297547 Pou3f3 Regulation of Psen1 1 0.00 0.41 0.25
120 INT86634 POMC Positive_regulation of TYR 2 0.42 0 0.24
121 INT235976 Binding of APC and Trav6-3 2 0.01 2.62 0.24
122 INT235974 Negative_regulation of Binding of APC and Trav6-3 1 0.00 1.15 0.24
123 INT260840 NRP2 Positive_regulation of Gene_expression of Bcl2 1 0.00 0.85 0.24
124 INT235972 Negative_regulation of Binding of APC and Bcr 1 0.01 1.15 0.24
125 INT235973 Binding of APC and Bcr 1 0.01 1.14 0.24
126 INT109408 Negative_regulation of APC Negative_regulation of Positive_regulation of RASGRP1 1 0.06 0.73 0.23
127 INT311911 Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23
128 INT250783 APC Negative_regulation of SERPINE1 1 0.06 0.86 0.23
129 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23
130 INT250782 APC Negative_regulation of F2 1 0.00 0.86 0.23
131 INT316111 APC Negative_regulation of SAE1 1 0.04 1.21 0.22
132 INT195663 APC Negative_regulation of Gene_expression of IL6 1 0.16 1.18 0.22
133 INT64382 Positive_regulation of Binding of YY1 and Tyr 1 0.11 0 0.21
134 INT353285 Prdx2 Regulation of Gene_expression of Col1a2 1 0.02 0.73 0.21
135 INT330051 Mapk8 Positive_regulation of Bcl2l11 1 0.13 0.46 0.21
136 INT64383 Binding of YY1 and Tyr 1 0.09 0 0.21
137 INT195212 Binding of CCR4 and Hand2 1 0.03 0.46 0.21
138 INT226511 Gene_expression of Il25 Positive_regulation of Gene_expression of Hand2 1 0.01 0.95 0.2
139 INT297545 Pou3f3 Regulation of Hes1 1 0.05 0.41 0.2
140 INT226514 BTPs Negative_regulation of Gene_expression of Hand2 1 0.03 0.22 0.2
141 INT316110 Binding of APC and SAE1 1 0.03 1.16 0.2
142 INT76865 Lmo4 Positive_regulation of Sds 1 0.02 0.38 0.2
143 INT338767 Positive_regulation of Binding of Hand1 and Hand2 1 0.07 0.5 0.2
144 INT115142 TGM7 Positive_regulation of Gene_expression of CITED2 1 0.02 0.45 0.2
145 INT226510 BTPs Negative_regulation of Hand2 1 0.03 0.22 0.2
146 INT175464 Hand2 Positive_regulation of Gene_expression of Sftpd 1 0.19 1.05 0.2
147 INT76866 Negative_regulation of Lmo4 Positive_regulation of Sds 1 0.02 0.38 0.2
148 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
149 INT28562 SOD1 Negative_regulation of Pacs1 1 0.03 2.63 0.19
150 INT228737 Rae1 Negative_regulation of Hand2 1 0.08 1.07 0.19
151 INT148835 asa Negative_regulation of Tyr 1 0.33 0.58 0.18
152 INT251492 Binding of HSPD1 and SOD1 1 0.02 1.45 0.18
153 INT250949 Binding of KIR3DL2 and SOD1 1 0.24 0.55 0.18
154 INT266046 Cstb Regulation of Gene_expression of Adrm1 1 0.00 0.7 0.18
155 INT316748 IL18 Positive_regulation of Regulation of Hand2 1 0.14 1.11 0.18
156 INT329843 Il4 Regulation of Hand2 1 0.04 0.87 0.18
157 INT306425 Positive_regulation of Binding of TBX1 and VCF 1 0.02 1.15 0.18
158 INT176133 AKT1 Regulation of BCL2 2 0.12 1.84 0.17
159 INT181457 Binding of CCL16 and Hand2 1 0.04 0.92 0.17
160 INT285026 Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
161 INT285022 Regulation of Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
162 INT306426 Binding of TBX1 and VCF 1 0.01 1.09 0.17
163 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17
164 INT155233 TXNIP Regulation of BCL2 1 0.23 0.15 0.17
165 INT285024 Bcl2 Regulation of Bak1 1 0.09 0.71 0.17
166 INT334106 APC Negative_regulation of NFKB1 1 0.25 1.37 0.17
167 INT229203 Binding of Bcl2 and Cyp2c11 1 0.36 1.2 0.17
168 INT155068 Csf2 Negative_regulation of Bcl2 1 0.12 1.88 0.17
169 INT162273 KITLG Negative_regulation of Gene_expression of Tyr 1 0.13 0.3 0.17
170 INT334108 APC Negative_regulation of TNF 1 0.13 1.36 0.17
171 INT168700 Positive_regulation of Binding of Nedd4 and Tyr 1 0.03 0.19 0.17
172 INT148836 asa Negative_regulation of Gene_expression of Tyr 1 0.43 0.52 0.16
173 INT347445 CD99 Positive_regulation of BCL2 1 0.17 0.95 0.16
174 INT194829 Gata3 Positive_regulation of IL13 1 0.01 0.12 0.15
175 INT294766 Cerk Regulation of Gene_expression of Hand2 1 0.13 0.32 0.15
176 INT292750 Akt1 Positive_regulation of Bcl2 1 0.01 1.67 0.15
177 INT194835 Gata3 Positive_regulation of IL5 1 0.01 0.12 0.15
178 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15
179 INT333241 Cxcl12 Regulation of Bcl2l11 1 0.18 1.11 0.15
180 INT194833 Binding of IL5 and Gata3 1 0.01 0.12 0.15
181 INT194827 Binding of IL13 and Gata3 1 0.01 0.12 0.15
182 INT347012 Hand2 Positive_regulation of Il4 1 0.01 0 0.14
183 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
184 INT68736 Binding of HLA-B and Tyr 1 0.01 0.23 0.14
185 INT306268 CRKL Positive_regulation of RASGRP1 1 0.02 0.54 0.14
186 INT95104 TGFBR2 Positive_regulation of BCL2 1 0.08 0.61 0.14
187 INT347015 Hand2 Regulation of Cd86 1 0.06 0 0.14
188 INT306272 CRKL Positive_regulation of JUN 1 0.05 0.54 0.14
189 INT294764 Binding of Hand2 and Cerk 1 0.17 0.31 0.14
190 INT252575 Rpe Negative_regulation of SOD1 1 0.03 2.39 0.14
191 INT235546 Stat6 Positive_regulation of Positive_regulation of Hand2 1 0.02 0.9 0.14
192 INT94763 PSEN2 Regulation of Positive_regulation of App 1 0.11 0.72 0.14
193 INT112304 Binding of Oprm1 and Tyr 1 0.01 0 0.14
194 INT347018 Cd80 Regulation of Hand2 1 0.03 0.05 0.13
195 INT309139 Edc4 Positive_regulation of Bcl2 1 0.03 0.12 0.13
196 INT131603 POMC Regulation of TYR 1 0.52 0 0.13
197 INT148594 Binding of BCL2 and CD34 1 0.39 1.17 0.13
198 INT289956 Binding of APC and ICAM1 1 0.04 0.5 0.13
199 INT242163 Wnt2 Positive_regulation of Regulation of Apc 1 0.13 0.71 0.13
200 INT353897 Negative_regulation of Prkcg Negative_regulation of Localization of Bcl2l11 1 0.08 0.4 0.13

Single Events

The table below shows the top 100 pain related interactions that have been reported for thymus development. They are ordered first by their pain relevance and then by number of times they were reported in thymus development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
2 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05
3 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
4 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
5 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22
6 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
7 INT112017 Regulation of Hand2 77 0.36 62.23 18.04
8 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
9 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
10 INT173505 Localization of Hand2 63 0.57 45.32 13.66
11 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
12 INT31990 Positive_regulation of SOD1 124 0.69 67.79 12.52
13 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4
14 INT222660 Phosphorylation of Tyr 2 0.06 5.31 12.33
15 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
16 INT2260 Gene_expression of Tyr 30 0.49 7.05 11.31
17 INT132586 Negative_regulation of Hand2 40 0.30 26.58 9.28
18 INT93045 Negative_regulation of Gene_expression of Hand2 31 0.43 25.26 9.24
19 INT43811 Positive_regulation of Tyr 14 0.45 2.52 8.86
20 INT13010 Gene_expression of TYR 38 0.65 14.81 8.84
21 INT57057 Gene_expression of APC 131 0.78 122.24 8.7
22 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
23 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
24 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
25 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
26 INT18185 Gene_expression of Tyr 32 0.76 12.52 8.17
27 INT5481 Binding of TYR 26 0.47 1.3 7.95
28 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
29 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
30 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
31 INT16631 Negative_regulation of APC 46 0.57 30.53 7.11
32 INT93046 Positive_regulation of Gene_expression of Hand2 27 0.47 24.54 7.01
33 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91
34 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
35 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
36 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02
37 INT103918 Phosphorylation of Tyr 12 0.47 10.12 5.96
38 INT128406 Gene_expression of Pax1 11 0.60 7.18 5.91
39 INT8157 Binding of Tyr 14 0.09 0.64 5.89
40 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
41 INT49025 Positive_regulation of TYR 14 0.69 7.15 5.84
42 INT60724 Gene_expression of Psen2 30 0.72 27 5.79
43 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7
44 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22
45 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22
46 INT57064 Positive_regulation of APC 72 0.66 48.5 5.08
47 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07
48 INT94466 Regulation of Gene_expression of Hand2 14 0.28 7.97 4.46
49 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3
50 INT32446 Localization of Tyr 11 0.68 1.31 4.25
51 INT116011 Positive_regulation of Gata3 5 0.31 3.17 4.21
52 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
53 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12
54 INT156131 Binding of Hand2 14 0.25 10.35 3.99
55 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91
56 INT63121 Binding of APC 29 0.41 23.02 3.8
57 INT105882 Phosphorylation of Bcl2 11 0.59 8.15 3.73
58 INT31528 Regulation of TYR 6 0.44 0.83 3.63
59 INT212563 Gene_expression of Adrm1 26 0.13 11.46 3.58
60 INT117836 Gene_expression of EPHB3 13 0.29 0.62 3.44
61 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4
62 INT59447 Negative_regulation of Tyr 12 0.56 4.57 3.32
63 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
64 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19
65 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16
66 INT75484 Gene_expression of Tgfbr1 21 0.64 13.36 3.15
67 INT91761 Gene_expression of PSEN2 38 0.75 22.93 3.03
68 INT105884 Binding of Bcl2 19 0.35 15.67 3
69 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
70 INT37435 Negative_regulation of Tyr 6 0.14 0.96 2.94
71 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
72 INT32787 Positive_regulation of Gene_expression of Tyr 5 0.38 0.37 2.77
73 INT49020 Negative_regulation of TYR 11 0.58 1.97 2.68
74 INT202419 Positive_regulation of Gene_expression of Gata3 6 0.52 5.47 2.6
75 INT31989 Binding of SOD1 43 0.47 19.38 2.55
76 INT163544 Binding of Psen1 40 0.36 15.28 2.42
77 INT221762 Regulation of Gene_expression of Adrm1 4 0.07 4.45 2.42
78 INT61441 Negative_regulation of Gene_expression of Tyr 3 0.10 0.69 2.4
79 INT147349 Localization of Bcl2 13 0.65 7.83 2.31
80 INT85630 Positive_regulation of Tyr 11 0.56 3.07 2.31
81 INT142677 Negative_regulation of Positive_regulation of Bcl2 4 0.36 3.09 2.24
82 INT17688 Positive_regulation of IKZF1 5 0.50 0.48 2.11
83 INT108250 Regulation of Prdx2 5 0.25 2.02 2.08
84 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
85 INT86671 Negative_regulation of Positive_regulation of Bcl2 6 0.57 3.83 2.03
86 INT60723 Localization of Psen2 5 0.68 2.11 2.02
87 INT96764 Positive_regulation of Gene_expression of SOD1 36 0.61 16.55 1.99
88 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
89 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
90 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
91 INT228129 Negative_regulation of Bcl2l11 10 0.58 11.08 1.93
92 INT129239 Positive_regulation of Positive_regulation of Hand2 5 0.43 2.81 1.93
93 INT107905 Gene_expression of BCL2L11 9 0.75 7.58 1.92
94 INT153684 Negative_regulation of Bcl2l11 3 0.31 1.19 1.89
95 INT101108 Localization of Bcl2 16 0.72 11.68 1.86
96 INT105883 Positive_regulation of Phosphorylation of Bcl2 8 0.32 5.67 1.86
97 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
98 INT111070 Negative_regulation of Gene_expression of Psen1 17 0.42 9.47 1.77
99 INT183276 Negative_regulation of Adrm1 10 0.04 7.25 1.74
100 INT3818 Regulation of Apc 13 0.39 12.52 1.68
101 INT60815 Binding of Bcl2l11 2 0.27 0.95 1.67
102 INT300417 Localization of Tyr 5 0.11 0.26 1.65
103 INT101958 Positive_regulation of Transcription of Bcl2 4 0.50 2.22 1.65
104 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
105 INT71780 Phosphorylation of TYR 12 0.34 17.21 1.62
106 INT137513 Negative_regulation of Positive_regulation of BCL2 6 0.35 5.3 1.62
107 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
108 INT101090 Gene_expression of IKZF1 6 0.77 2.98 1.58
109 INT27293 Regulation of SOD1 21 0.53 15.73 1.55
110 INT282434 Regulation of Gene_expression of Psen1 9 0.50 2.85 1.52
111 INT100672 Transcription of Hand2 9 0.42 2.84 1.47
112 INT250114 Gene_expression of Hoxa3 36 0.77 23.04 1.46
113 INT116014 Transcription of Gata3 4 0.63 2.24 1.46
114 INT78646 Regulation of Psen2 4 0.20 1.78 1.42
115 INT116015 Regulation of Gata3 3 0.22 1.41 1.42
116 INT116008 Binding of Gata3 2 0.34 1.37 1.41
117 INT220177 Binding of Apc 21 0.37 15.34 1.37
118 INT108249 Negative_regulation of Prdx2 3 0.32 1.85 1.36
119 INT181509 Negative_regulation of Psen1 17 0.57 11.53 1.35
120 INT110434 Positive_regulation of Gene_expression of Apc 20 0.50 11.37 1.3
121 INT101107 Positive_regulation of Localization of Bcl2 3 0.48 3.13 1.28
122 INT116016 Positive_regulation of Positive_regulation of Gata3 2 0.21 0.5 1.28
123 INT228128 Gene_expression of Bcl2l11 31 0.67 18.31 1.25
124 INT107904 Positive_regulation of Gene_expression of BCL2L11 3 0.53 2.22 1.24
125 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
126 INT175452 Negative_regulation of Positive_regulation of Hand2 4 0.21 3.78 1.21
127 INT303667 Regulation of BCL2L11 3 0.16 1.03 1.21
128 INT83805 Binding of EPHB3 1 0.00 1.15 1.19
129 INT310164 Negative_regulation of Gene_expression of Tgfbr1 9 0.40 6.11 1.17
130 INT102073 Regulation of Gene_expression of APC 5 0.45 6.09 1.15
131 INT93506 Negative_regulation of Gene_expression of Tyr 2 0.57 1.61 1.15
132 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
133 INT103919 Negative_regulation of Phosphorylation of Tyr 2 0.32 2.01 1.12
134 INT102074 Positive_regulation of Gene_expression of APC 20 0.50 13.66 1.1
135 INT172855 Binding of Bcl2 37 0.32 23.41 1.09
136 INT70021 Localization of BCL2 23 0.74 21.6 1.09
137 INT293195 Positive_regulation of Phosphorylation of Tyr 1 0.01 0.76 1.08
138 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
139 INT159543 Localization of SOD1 29 0.75 8.62 1.06
140 INT2293 Localization of TYR 3 0.61 0.16 1.06
141 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
142 INT179583 Gene_expression of Lmo4 5 0.41 1.97 1.03
143 INT129398 Negative_regulation of Gene_expression of SOD1 22 0.43 7.11 1.02
144 INT78645 Negative_regulation of Gene_expression of Psen2 1 0.14 0.13 1.01
145 INT49021 Transcription of TYR 2 0.68 0.58 0.99
146 INT235516 Positive_regulation of Localization of Hand2 4 0.36 3.04 0.97
147 INT24266 Negative_regulation of IKZF1 6 0.37 1.55 0.96
148 INT226419 Negative_regulation of Localization of Hand2 4 0.30 3.17 0.96
149 INT108243 Positive_regulation of Prdx2 3 0.34 0.85 0.95
150 INT91771 Positive_regulation of Gene_expression of PSEN1 13 0.49 8.93 0.93
151 INT228130 Positive_regulation of Bcl2l11 14 0.49 10 0.9
152 INT242134 Localization of Apc 8 0.74 4.83 0.88
153 INT51728 Binding of Tyr 6 0.42 0.85 0.88
154 INT151115 Regulation of Regulation of Bcl2 4 0.21 4.12 0.88
155 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
156 INT265313 Positive_regulation of Tgfbr1 8 0.66 2.95 0.87
157 INT59006 Protein_catabolism of Tyr 1 0.30 0 0.87
158 INT312362 Gene_expression of PBX1 1 0.56 4.48 0.87
159 INT92117 Phosphorylation of BCL2 26 0.80 9.93 0.86
160 INT112014 Negative_regulation of Regulation of Hand2 3 0.34 2.07 0.86
161 INT78647 Positive_regulation of Localization of Psen2 1 0.16 0.14 0.83
162 INT258932 Positive_regulation of TBX1 3 0.39 2.73 0.82
163 INT312364 Positive_regulation of PBX1 1 0.43 4.69 0.81
164 INT237406 Positive_regulation of Binding of Psen1 1 0.29 0 0.8
165 INT70019 Binding of BCL2 25 0.47 17.55 0.79
166 INT101091 Regulation of IKZF1 3 0.09 0.3 0.79
167 INT94756 Positive_regulation of PSEN2 8 0.49 4.59 0.77
168 INT109404 Transcription of BCL2 6 0.69 4.49 0.77
169 INT286313 Transcription of Psen1 9 0.70 2.26 0.76
170 INT193849 Positive_regulation of Gene_expression of Psen2 5 0.44 4.92 0.76
171 INT161947 Positive_regulation of TGFBR1 2 0.52 1.6 0.76
172 INT259113 Gene_expression of LMO4 1 0.78 71.49 0.76
173 INT124844 Regulation of Positive_regulation of Bcl2 3 0.43 2.55 0.75
174 INT155392 Negative_regulation of Negative_regulation of Bcl2 3 0.21 1.64 0.74
175 INT78649 Binding of Psen2 7 0.36 5.9 0.73
176 INT148282 Positive_regulation of Gene_expression of TYR 3 0.56 0.6 0.73
177 INT78648 Regulation of Binding of Psen2 1 0.14 0.2 0.73
178 INT134444 Positive_regulation of Binding of Bcl2 3 0.47 2.67 0.72
179 INT86408 Negative_regulation of Positive_regulation of Tyr 1 0.01 0.18 0.72
180 INT28561 Regulation of Gene_expression of SOD1 9 0.61 2.83 0.71
181 INT116012 Regulation of Positive_regulation of Gata3 1 0.20 0.07 0.71
182 INT57062 Regulation of APC 24 0.58 14.3 0.7
183 INT116006 Positive_regulation of Transcription of Gata3 1 0.21 0.07 0.7
184 INT116010 Positive_regulation of Binding of Gata3 1 0.31 0.07 0.7
185 INT80674 Negative_regulation of Gene_expression of APC 16 0.59 18.14 0.69
186 INT19787 Regulation of Tyr 1 0.30 0.46 0.68
187 INT271488 Negative_regulation of Negative_regulation of Hand2 3 0.18 2.36 0.67
188 INT53214 Regulation of Tyr 3 0.05 0.8 0.66
189 INT78183 Negative_regulation of Adrm1 8 0.09 3.4 0.65
190 INT99390 Regulation of Ctnnb1 4 0.62 3.12 0.64
191 INT193672 Gene_expression of Prdx2 3 0.50 2.75 0.64
192 INT202416 Negative_regulation of Gata3 2 0.32 1.17 0.64
193 INT32447 Regulation of Localization of Tyr 1 0.26 0.24 0.64
194 INT264709 Gene_expression of Hes1 24 0.76 7.04 0.63
195 INT91765 Positive_regulation of Gene_expression of PSEN2 8 0.49 4.57 0.63
196 INT212562 Positive_regulation of Adrm1 16 0.10 5.08 0.62
197 INT18483 Protein_catabolism of Tyr 4 0.97 0.58 0.6
198 INT290660 Negative_regulation of Gene_expression of Gata3 1 0.25 1.52 0.6
199 INT70025 Positive_regulation of Positive_regulation of BCL2 3 0.27 0.96 0.58
200 INT132588 Positive_regulation of Negative_regulation of Hand2 1 0.03 0.47 0.58
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