GO:0048596

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Name embryonic camera-type eye morphogenesis
Categary Process
Go Slim No
Go Link GO:0048596
Unique Molecular Interactions 294
Total Molecular Interactions 428
Total Single Events 4450
Pain Genes Associated 23

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for embryonic camera-type eye morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported for embryonic camera-type eye morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT200322 Binding of Rest and Sp3 1 0.39 2.93 3.98
2 INT124547 Trib3 Regulation of Regulation of Th 1 0.02 0.79 2.64
3 INT63939 Vta1 Positive_regulation of Th 1 0.14 0 1.61
4 INT40887 Penk Regulation of Th 1 0.04 0 1.53
5 INT157540 Binding of SP1 and YY1 1 0.41 2.55 1.42
6 INT106070 Positive_regulation of Oprl1 Positive_regulation of TH 1 0.13 0.15 1.36
7 INT60989 Ngf Regulation of Th 1 0.17 0 1.34
8 INT98833 Th Regulation of Gene_expression of Drd2 1 0.19 0.64 1.27
9 INT98832 Th Regulation of Dbh 1 0.32 0.53 1.2
10 INT90644 Slc6a3 Positive_regulation of Th 1 0.51 0 1.2
11 INT141245 Prkaca Regulation of Gene_expression of Th 1 0.15 0.17 1.17
12 INT141246 Trib3 Regulation of Gene_expression of Th 1 0.02 0.17 1.17
13 INT60990 Bdnf Negative_regulation of Th 1 0.15 0 1.17
14 INT106069 TH Positive_regulation of Th 1 0.07 0.16 1.14
15 INT88446 Uncx Positive_regulation of Th 1 0.13 0 1.1
16 INT44838 Pitpnm1 Negative_regulation of Th 1 0.02 0 1.09
17 INT31547 Binding of Th and Vip 1 0.31 0 1.08
18 INT134970 Positive_regulation of Binding of OPRK1 and SP1 1 0.00 0 1.05
19 INT134969 Binding of OPRK1 and SP1 1 0.00 0 1.04
20 INT221 Chd7 Negative_regulation of Th 1 0.02 0 1.04
21 INT41175 Adra2a Regulation of Th 1 0.59 0 1.04
22 INT200323 Binding of Oprm1 and Sp3 1 0.39 0 0.99
23 INT31548 Binding of Th and Dbh 1 0.35 0 0.98
24 INT165941 Bmp7 Positive_regulation of Penk 1 0.28 0.43 0.95
25 INT165942 Bmp7 Positive_regulation of Transcription of Pomc 1 0.29 0.43 0.95
26 INT165940 Bmp7 Positive_regulation of Pomc 1 0.29 0.43 0.95
27 INT6975 Zeb1 Positive_regulation of St8sia1 1 0.03 0.17 0.91
28 INT77254 Binding of gr and Sp1 1 0.04 0.4 0.9
29 INT103611 Mdk Negative_regulation of Phosphorylation of Sp1 1 0.01 0.28 0.88
30 INT184916 Binding of da and Th 1 0.09 1.22 0.87
31 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
32 INT122687 Binding of Galr2 and Th 1 0.13 0.07 0.83
33 INT122688 Binding of Galr1 and Th 1 0.14 0.07 0.83
34 INT122686 Binding of Galr3 and Th 1 0.14 0.07 0.83
35 INT63940 Negative_regulation of Vta1 Positive_regulation of Th 1 0.13 0 0.81
36 INT184918 da Positive_regulation of Negative_regulation of Th 1 0.14 0.14 0.77
37 INT147278 Negative_regulation of Calca Positive_regulation of Th 1 0.41 0.76 0.74
38 INT147277 Calca Positive_regulation of Th 1 0.48 0.76 0.74
39 INT157539 Binding of SP1 and Regulation of Gene_expression of OPRM1 1 0.36 1.2 0.72
40 INT98956 Positive_regulation of Binding of NR5A2 and SP1 1 0.00 0 0.7
41 INT98951 Positive_regulation of Binding of NR5A2 and SP3 1 0.00 0 0.7
42 INT144367 Gdnf Negative_regulation of Positive_regulation of Th 1 0.11 0.77 0.7
43 INT207542 Sp1 Regulation of Oprm1 1 0.15 0.06 0.7
44 INT98957 Binding of NR5A2 and SP3 1 0.00 0 0.7
45 INT207540 Tfap2a Regulation of Oprm1 1 0.13 0.06 0.7
46 INT98958 Binding of NR5A2 and SP1 1 0.00 0 0.7
47 INT135207 Gmeb1 Regulation of Gene_expression of Tfap2a 1 0.07 0.48 0.69
48 INT135206 Ighen Regulation of Gene_expression of Tfap2a 1 0.06 0.48 0.69
49 INT135202 Tfap2a Regulation of Gene_expression of Ighen 1 0.06 0.48 0.69
50 INT135213 Tfap2a Regulation of Gene_expression of Nfkb1 1 0.02 0.48 0.69
51 INT135211 Nfkb1 Regulation of Gene_expression of Tfap2a 1 0.02 0.48 0.69
52 INT135204 Tfap2a Regulation of Gene_expression of Gmeb1 1 0.10 0.48 0.69
53 INT207543 Tfap2a Regulation of Qsox1 1 0.04 0.06 0.67
54 INT207547 Sp1 Regulation of Qsox1 1 0.05 0.06 0.67
55 INT231533 IL4 Positive_regulation of LRP5 1 0.00 0.87 0.67
56 INT149899 Ihh Positive_regulation of Mmp7 1 0.04 1.69 0.65
57 INT313435 Syp Regulation of Th 1 0.43 1.6 0.64
58 INT7958 LOC686180 Positive_regulation of Gene_expression of Th 1 0.02 0 0.64
59 INT123416 Gene_expression of Sp1 Positive_regulation of Oprm1 1 0.60 0 0.63
60 INT98955 Positive_regulation of Binding of SP3 and CFHR4 1 0.00 0 0.62
61 INT98953 Positive_regulation of Binding of SP1 and CFHR4 1 0.00 0 0.62
62 INT98954 Binding of SP1 and CFHR4 1 0.00 0 0.61
63 INT98952 Binding of SP3 and CFHR4 1 0.00 0 0.61
64 INT200348 Sp3 Negative_regulation of Gene_expression of Oprm1 1 0.48 0.4 0.55
65 INT228852 Th Positive_regulation of Vta1 1 0.04 0 0.53
66 INT228851 Th Positive_regulation of Mtf2 1 0.02 0 0.52
67 INT184922 Negative_regulation of Th Negative_regulation of da 1 0.12 0.18 0.52
68 INT244028 Positive_regulation of Binding of Cacnb3 and Tfap2a 1 0.01 0.24 0.49
69 INT244037 Positive_regulation of Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
70 INT244000 Positive_regulation of Binding of Tfap2a and Dnm1 1 0.04 0.24 0.49
71 INT244035 Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
72 INT243997 Binding of Tfap2a and Dnm1 1 0.03 0.24 0.49
73 INT244060 Binding of Cacnb3 and Tfap2a 1 0.00 0.24 0.49
74 INT7957 Calca Positive_regulation of Gene_expression of Th 1 0.39 0 0.47
75 INT149894 Ihh Positive_regulation of Localization of Mmp14 1 0.04 2.06 0.47
76 INT249021 Gabrg1 Negative_regulation of Th 1 0.08 0.06 0.44
77 INT121837 Sct Positive_regulation of Th 1 0.23 0.06 0.43
78 INT139487 Oprm1 Positive_regulation of Th 1 0.26 0.1 0.42
79 INT147280 Binding of Pecam1 and Th 1 0.29 0.41 0.41
80 INT302871 Negative_regulation of Adora2a Positive_regulation of Phosphorylation of Th 1 0.26 0.12 0.4
81 INT7625 Man2a2 Regulation of Th 1 0.01 0.07 0.4
82 INT89332 Binding of SP1 and SP3 1 0.30 0.76 0.39
83 INT278944 ZEB1 Negative_regulation of IL1B 1 0.00 1.09 0.39
84 INT31794 Hps6 Positive_regulation of Th 1 0.03 0 0.38
85 INT200313 Sp3 Regulation of Oprm1 1 0.10 0.07 0.38
86 INT200301 Sp3 Regulation of Rorb 1 0.00 0.07 0.38
87 INT278960 ZEB1 Negative_regulation of MMP3 1 0.00 1.05 0.38
88 INT278943 ZEB1 Negative_regulation of Gene_expression of MMP3 1 0.00 1.05 0.38
89 INT113040 IHH Regulation of Gene_expression of INS 1 0.12 0.37 0.37
90 INT167558 Gene_expression of Sp1 Positive_regulation of Oprm1 1 0.03 0.07 0.36
91 INT167551 Binding of MECP2 and SP3 1 0.01 0.06 0.35
92 INT200333 Binding of Rest and Sp1 1 0.24 0.07 0.35
93 INT200316 Sp1 Regulation of Gene_expression of Rest 1 0.31 0 0.35
94 INT301054 Tfap2a Regulation of Gene_expression of Faslg 1 0.00 1.23 0.34
95 INT173476 Th Regulation of Gene_expression of Bcar1 1 0.10 0 0.34
96 INT34855 Negative_regulation of Maoa Negative_regulation of Th 1 0.17 0 0.34
97 INT173478 Th Regulation of Localization of Ins1 1 0.13 0 0.34
98 INT149897 Ihh Positive_regulation of Mmp14 1 0.03 0.93 0.33
99 INT285565 Positive_regulation of Zeb1 Negative_regulation of IL2 1 0.02 0.62 0.33
100 INT149896 Ihh Regulation of Gene_expression of Col1a1 1 0.06 0.89 0.33
101 INT149895 Ihh Regulation of Localization of Mmp7 1 0.03 0.98 0.33
102 INT285563 Zeb1 Negative_regulation of IL2 1 0.01 0.62 0.33
103 INT149902 Ihh Positive_regulation of SGCG 1 0.45 0.76 0.32
104 INT153019 nct Positive_regulation of Transcription of Th 1 0.19 0.61 0.32
105 INT153020 nct Positive_regulation of Gene_expression of Th 1 0.19 0.61 0.32
106 INT253576 Binding of Lpl and Sp3 1 0.22 0.85 0.32
107 INT290614 Binding of Th and RLS 1 0.21 3.26 0.31
108 INT90643 Negative_regulation of Slc6a3 Positive_regulation of Th 1 0.47 0 0.3
109 INT200351 Sp1 Positive_regulation of Gene_expression of Rest 1 0.34 0.07 0.3
110 INT55404 Binding of ENG and Th 1 0.02 0 0.3
111 INT314484 TH Positive_regulation of RLS 1 0.01 1.66 0.29
112 INT78484 Binding of DBH and TH 1 0.09 0 0.28
113 INT149898 Ihh Regulation of Localization of Mmp14 1 0.03 1.29 0.27
114 INT96788 Binding of SP3 and NR2F2 1 0.24 0.27 0.27
115 INT96789 Binding of SP1 and NR2F2 1 0.24 0.27 0.27
116 INT96787 SP1 Positive_regulation of GDF15 1 0.08 0.27 0.27
117 INT96790 SP3 Positive_regulation of GDF15 1 0.20 0.26 0.27
118 INT125515 SP1 Regulation of GDF15 1 0.14 0.47 0.26
119 INT169837 Sp1 Positive_regulation of Gene_expression of Kcnq3 1 0.04 0.08 0.26
120 INT126886 Protein_catabolism of SP1 Negative_regulation of Gene_expression of VEGFA 1 0.03 0.49 0.26
121 INT169836 Sp1 Positive_regulation of Gene_expression of Kcnq2 1 0.05 0.08 0.26
122 INT118461 Bmp7 Positive_regulation of Th 1 0.31 0.06 0.25
123 INT260739 Mapk14 Regulation of Positive_regulation of Sp1 1 0.01 1.06 0.25
124 INT200309 Positive_regulation of Binding of Rest and Sp3 1 0.41 0.88 0.24
125 INT329432 Binding of CCR6 and TH 1 0.00 0.47 0.23
126 INT329431 Binding of CCL20 and TH 1 0.00 0.47 0.23
127 INT210798 Ihh Positive_regulation of Itgbl1 1 0.34 0 0.23
128 INT253568 Negative_regulation of Binding of Lpl and Sp3 1 0.19 0.37 0.22
129 INT335888 Lrp5 Negative_regulation of Gene_expression of Tph1 1 0.22 0.15 0.21
130 INT189196 RASGRP1 Positive_regulation of SP1 1 0.05 0.63 0.21
131 INT115142 TGM7 Positive_regulation of Gene_expression of CITED2 1 0.02 0.45 0.2
132 INT61987 Th Regulation of Penk 1 0.46 0 0.2
133 INT136462 Negative_regulation of Ptgs1 Negative_regulation of Gene_expression of Sp1 1 0.01 0.65 0.19
134 INT281477 Binding of Pten and Th 1 0.28 0.4 0.19
135 INT349504 Ptpn2 Negative_regulation of Th 1 0.23 2 0.19
136 INT251665 LRP5 Negative_regulation of Ache 1 0.31 0.39 0.19
137 INT210795 Ihh Negative_regulation of Itgb1 1 0.30 0 0.17
138 INT313453 Siglec1 Regulation of Th 1 0.02 0.61 0.17
139 INT317322 Snca Regulation of Positive_regulation of Th 1 0.01 0.23 0.17
140 INT88450 Uncx Regulation of Gene_expression of Th 1 0.06 0 0.17
141 INT210782 Ihh Negative_regulation of Itgbl1 1 0.31 0 0.16
142 INT349503 Ptpn2 Negative_regulation of Gene_expression of Th 1 0.23 0.7 0.16
143 INT210804 Ihh Negative_regulation of Timp4 1 0.32 0 0.16
144 INT213551 Proc Regulation of Bmp7 1 0.00 0.15 0.14
145 INT88410 BMP7 Negative_regulation of CDK2 1 0.35 0 0.14
146 INT253564 Binding of Lpl and Sp1 1 0.13 0.9 0.14
147 INT261456 Sftpd Positive_regulation of Gene_expression of Th 1 0.10 0.77 0.13
148 INT313441 Th Regulation of Siglec1 1 0.02 0.22 0.13
149 INT223535 Binding of HAND1 and Pax6 1 0.33 0.92 0.13
150 INT200328 Sp3 Positive_regulation of Gene_expression of Oprm1 1 0.38 0 0.13
151 INT313439 Syp Negative_regulation of Th 1 0.30 0.14 0.13
152 INT223526 Binding of Pax6 and Tcf3 1 0.33 0.92 0.13
153 INT197317 Nr4a2 Regulation of Gene_expression of Th 1 0.03 0.07 0.12
154 INT200315 Binding of Sp1 and Sp3 1 0.29 0 0.12
155 INT68802 Sp1 Regulation of Gene_expression of Pebp1 1 0.24 0 0.12
156 INT253572 Binding of Csnk2a2 and Sp1 1 0.17 0 0.11
157 INT200320 Binding of Sp3 and Negative_regulation of Gene_expression of Oprm1 1 0.35 0.4 0.1
158 INT210992 Binding of KCNMA1 and SP3 1 0.00 0.17 0.1
159 INT210989 Binding of FSCN1 and SP3 1 0.00 0.17 0.1
160 INT313454 Negative_regulation of Syp Negative_regulation of Th 1 0.30 0.14 0.1
161 INT171163 Creb1 Regulation of Sp1 1 0.03 0.62 0.1
162 INT194822 Negative_regulation of MAPK1 Negative_regulation of Binding of Sp1 1 0.04 0.05 0.1
163 INT210988 Binding of SP3 and PKDREJ 1 0.01 0.17 0.1
164 INT210994 Binding of SEA and SP3 1 0.00 0.17 0.1
165 INT165161 Ihh Positive_regulation of Sostdc1 1 0.58 0.07 0.09
166 INT165160 Regulation of Ihh Positive_regulation of Sostdc1 1 0.23 0.07 0.09
167 INT253571 Positive_regulation of Binding of Lpl and Sp1 1 0.17 0.42 0.09
168 INT165158 Positive_regulation of Ihh Positive_regulation of Sostdc1 1 0.42 0.07 0.09
169 INT253579 Negative_regulation of Binding of Lpl and Sp1 1 0.15 0.42 0.09
170 INT129624 Bmp7 Positive_regulation of Gene_expression of Id2 1 0.26 0.31 0.08
171 INT210788 Ihh Negative_regulation of Coro1a 1 0.02 0 0.08
172 INT313442 Th Regulation of Phosphorylation of Syp 1 0.32 0 0.08
173 INT129623 Bmp7 Positive_regulation of Gene_expression of Id3 1 0.37 0.31 0.08
174 INT129625 Id2 Positive_regulation of Gene_expression of Bmp7 1 0.24 0.31 0.08
175 INT129622 Id3 Positive_regulation of Gene_expression of Bmp7 1 0.25 0.31 0.08
176 INT313459 Gene_expression of Syp Negative_regulation of Th 1 0.30 0.49 0.08
177 INT313437 Th Regulation of Phosphorylation of Siglec1 1 0.04 0 0.08
178 INT210790 Ihh Negative_regulation of Cdkn1c 1 0.30 0 0.08
179 INT313509 Binding of ALOX5 and SP1 1 0.07 1.51 0.08
180 INT210787 Ihh Negative_regulation of Nr3c1 1 0.33 0 0.08
181 INT129627 Bmp7 Positive_regulation of Id2 1 0.24 0.25 0.07
182 INT129626 Bmp7 Positive_regulation of Id3 1 0.25 0.25 0.07
183 INT125208 Pou4f1 Negative_regulation of Gene_expression of Th 1 0.28 0.67 0.07
184 INT125209 Pou4f1 Positive_regulation of Gene_expression of Th 1 0.33 0.67 0.07
185 INT253570 Binding of Csnk2a2 and Sp3 1 0.16 0.2 0.07
186 INT253577 Csnk2a2 Positive_regulation of Phosphorylation of Sp1 1 0.17 0.37 0.06
187 INT313450 Th Regulation of Syp 1 0.32 0.6 0.06
188 INT201973 Bmp7 Positive_regulation of ap 1 0.00 0.18 0.06
189 INT118462 BMP7 Regulation of Bmp7 1 0.19 0 0.06
190 INT242618 Binding of Slc18a3 and Th 1 0.13 0.26 0.05
191 INT233850 Zeb1 Positive_regulation of Itk 1 0.04 0.58 0.04
192 INT233848 Zeb1 Positive_regulation of Snai1 1 0.07 0.58 0.04
193 INT233853 Zeb1 Positive_regulation of Snai2 1 0.09 0.58 0.04
194 INT295718 Binding of PTGER2 and Positive_regulation of Positive_regulation of SP1 1 0.02 0.58 0.04
195 INT233851 Twist1 Positive_regulation of Zeb1 1 0.06 0.58 0.04
196 INT254433 Binding of Lrp5 and Sost 2 0.39 1.51 0.03
197 INT313433 53T Regulation of Th 1 0.00 0 0.03
198 INT287234 PDLIM7 Positive_regulation of Gene_expression of BMP7 1 0.14 0.12 0.03
199 INT253574 Sp3 Positive_regulation of Lpl 1 0.22 0 0.03
200 INT167565 Binding of ERG and LRP5 1 0.02 0.94 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported for embryonic camera-type eye morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported in embryonic camera-type eye morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT4740 Gene_expression of Th 298 0.78 61.27 154.03
2 INT218 Positive_regulation of Th 245 0.70 40.5 120.1
3 INT7327 Regulation of Th 164 0.62 29.67 110.14
4 INT217 Negative_regulation of Th 134 0.59 26.83 62.63
5 INT350 Localization of Th 79 0.80 10.26 41.17
6 INT30817 Gene_expression of Th 142 0.76 33.56 38.12
7 INT7326 Transcription of Th 83 0.72 13.5 35.33
8 INT6558 Positive_regulation of Gene_expression of Th 56 0.70 9.64 30.89
9 INT7956 Regulation of Gene_expression of Th 44 0.61 8.26 29.31
10 INT4781 Gene_expression of TH 68 0.73 26.92 24.01
11 INT26719 Negative_regulation of Gene_expression of Th 38 0.58 11.87 22.78
12 INT13643 Phosphorylation of Th 20 0.82 1.9 20.97
13 INT24240 Positive_regulation of Th 60 0.70 9.92 20.18
14 INT219 Negative_regulation of Th 55 0.59 20.88 17.09
15 INT24241 Phosphorylation of Th 35 0.81 8.69 16.06
16 INT13716 Positive_regulation of TH 33 0.68 19.11 16
17 INT41558 Localization of Sp1 9 0.48 0.56 14.9
18 INT109264 Positive_regulation of Transcription of Th 17 0.50 4.73 14.33
19 INT24082 Negative_regulation of Sp1 13 0.40 1.19 13.11
20 INT31368 Positive_regulation of Positive_regulation of Th 19 0.51 2.2 12.68
21 INT141 Binding of Th 21 0.48 3.53 11.04
22 INT78567 Positive_regulation of Gene_expression of Th 25 0.68 5.32 10.75
23 INT48496 Regulation of Transcription of Th 16 0.54 2.29 10.02
24 INT109265 Transcription of Th 18 0.68 4.5 8.21
25 INT26643 Negative_regulation of Positive_regulation of Th 12 0.59 1.26 7.74
26 INT7624 Positive_regulation of Regulation of Th 7 0.50 2.41 7
27 INT122896 Negative_regulation of TH 23 0.57 9.27 6.88
28 INT109266 Negative_regulation of Transcription of Th 9 0.42 2.5 6.85
29 INT66987 Regulation of Th 23 0.61 7.86 6.8
30 INT3506 Localization of TH 12 0.81 0.78 6.66
31 INT48555 Binding of SP1 30 0.46 11.38 6.53
32 INT7569 Positive_regulation of Transcription of Th 19 0.70 2.6 6.17
33 INT41604 Negative_regulation of Localization of Sp1 2 0.30 0.32 5.86
34 INT30317 Regulation of TH 14 0.43 7.27 5.38
35 INT7623 Regulation of Regulation of Th 11 0.44 1.31 5.16
36 INT24236 Positive_regulation of Phosphorylation of Th 12 0.61 3.68 4.87
37 INT37151 Localization of Th 13 0.57 3.11 4.82
38 INT40620 Regulation of Positive_regulation of Th 9 0.45 2.45 4.69
39 INT198736 Binding of Sp3 23 0.40 4.77 4.42
40 INT30165 Positive_regulation of Phosphorylation of Th 8 0.56 0.75 4.22
41 INT123411 Gene_expression of Sp1 15 0.69 4.2 3.79
42 INT77823 Negative_regulation of Negative_regulation of Th 9 0.59 1.56 3.79
43 INT40368 Positive_regulation of LRP5 5 0.49 3.19 3.51
44 INT141148 Gene_expression of BMP7 24 0.71 14.34 3.44
45 INT30166 Regulation of Phosphorylation of Th 4 0.50 0.52 3.33
46 INT100295 Gene_expression of Bmp7 27 0.78 14.34 3.3
47 INT41559 Positive_regulation of Sp1 7 0.45 2.65 3.24
48 INT102901 Regulation of Gene_expression of Th 12 0.60 2.42 3.22
49 INT123409 Binding of Sp1 20 0.39 3.18 3.15
50 INT4782 Positive_regulation of Gene_expression of TH 12 0.47 7.36 2.95
51 INT103607 Binding of Sp1 7 0.42 1.26 2.92
52 INT113041 Gene_expression of IHH 9 0.78 5.83 2.87
53 INT93213 Phosphorylation of Sp1 5 0.67 0.93 2.84
54 INT89336 Binding of SP3 6 0.47 1.75 2.63
55 INT106066 Negative_regulation of Positive_regulation of TH 1 0.18 0.22 2.6
56 INT106068 Positive_regulation of Positive_regulation of TH 1 0.21 0.22 2.59
57 INT24902 Gene_expression of SP1 17 0.71 8.11 2.58
58 INT4704 Positive_regulation of Negative_regulation of Th 4 0.50 0.06 2.56
59 INT23998 Positive_regulation of Sp1 4 0.40 0.51 2.56
60 INT13644 Negative_regulation of Phosphorylation of Th 2 0.43 0.06 2.51
61 INT184914 Negative_regulation of Gene_expression of Th 15 0.43 9.17 2.46
62 INT103609 Transcription of Sp1 1 0.11 0.97 2.42
63 INT15210 Negative_regulation of Transcription of Th 9 0.59 0.47 2.37
64 INT15209 Negative_regulation of Regulation of Th 6 0.51 1.64 2.16
65 INT103608 Negative_regulation of Binding of Sp1 4 0.35 0.69 2.1
66 INT41495 Regulation of Sp1 7 0.42 2.96 2.05
67 INT41557 Gene_expression of Sp1 5 0.68 1.17 2.04
68 INT1834 Positive_regulation of Binding of Th 1 0.46 0 1.91
69 INT314510 Protein_catabolism of TH 1 0.10 3.28 1.86
70 INT3505 Binding of TH 5 0.39 2.6 1.8
71 INT24906 Negative_regulation of SP1 8 0.40 4.48 1.77
72 INT145545 Transcription of TH 3 0.67 1.48 1.64
73 INT41605 Positive_regulation of Localization of Sp1 1 0.05 0 1.58
74 INT136459 Gene_expression of Sp3 6 0.64 1.97 1.47
75 INT207521 Gene_expression of Tfap2a 7 0.48 1.89 1.45
76 INT165538 Binding of Bmp7 5 0.37 1.87 1.39
77 INT287241 Positive_regulation of BMP7 10 0.43 2.68 1.38
78 INT123414 Transcription of Sp1 5 0.48 2.2 1.38
79 INT94692 Positive_regulation of Gene_expression of Sp1 3 0.17 0.39 1.28
80 INT24000 Regulation of Sp1 2 0.22 1.25 1.27
81 INT97869 Negative_regulation of Positive_regulation of Th 3 0.25 0.79 1.23
82 INT48554 Positive_regulation of SP1 12 0.49 3.64 1.2
83 INT108519 Binding of Lrp6 8 0.44 1.47 1.19
84 INT140983 Gene_expression of Ihh 7 0.78 2.06 1.15
85 INT26760 Negative_regulation of Localization of Th 2 0.40 0.09 1.14
86 INT93216 Negative_regulation of Phosphorylation of Sp1 2 0.14 0.4 1.13
87 INT50267 Negative_regulation of Negative_regulation of Th 3 0.42 1.57 1.12
88 INT89670 Negative_regulation of Binding of Th 2 0.43 0.28 1.12
89 INT84511 Positive_regulation of Tfap2a 3 0.27 0.72 1.04
90 INT123408 Positive_regulation of Gene_expression of Sp1 2 0.62 0.9 0.96
91 INT208792 Negative_regulation of Gene_expression of TH 6 0.35 1.11 0.94
92 INT243974 Binding of Tfap2a 7 0.18 1.36 0.93
93 INT123407 Negative_regulation of Binding of Sp1 6 0.47 0.72 0.93
94 INT136458 Negative_regulation of Sp3 3 0.39 1.53 0.93
95 INT200272 Localization of Sp1 3 0.57 0.06 0.93
96 INT198953 Regulation of Regulation of Th 1 0.01 0.1 0.93
97 INT24242 Negative_regulation of Phosphorylation of Th 3 0.38 1.44 0.9
98 INT208789 Negative_regulation of Localization of TH 2 0.25 0 0.89
99 INT50266 Regulation of Negative_regulation of Th 1 0.42 0.94 0.88
100 INT285477 Positive_regulation of Zeb1 2 0.17 0.86 0.86
101 INT53309 Regulation of Localization of Th 1 0.39 0 0.84
102 INT221796 Positive_regulation of Gene_expression of Tfap2a 2 0.10 1.19 0.83
103 INT123410 Negative_regulation of Gene_expression of Sp1 3 0.38 1.01 0.82
104 INT72334 Negative_regulation of LRP5 7 0.35 1.71 0.81
105 INT141150 Localization of BMP7 4 0.56 2.84 0.76
106 INT40369 Gene_expression of LRP5 8 0.55 5.63 0.74
107 INT207535 Transcription of Tfap2a 3 0.31 0.98 0.74
108 INT135197 Gene_expression of Tfap2a 1 0.45 0.48 0.69
109 INT231558 Regulation of LRP5 2 0.24 1.02 0.68
110 INT98967 Localization of SP1 2 0.60 0.15 0.66
111 INT24905 Negative_regulation of Gene_expression of SP1 4 0.39 2.05 0.65
112 INT122934 Negative_regulation of Regulation of TH 1 0.03 0.56 0.63
113 INT100294 Positive_regulation of Gene_expression of Bmp7 8 0.46 5.41 0.61
114 INT113042 Localization of IHH 1 0.70 0.77 0.61
115 INT207529 Localization of Tfap2a 2 0.34 0.13 0.6
116 INT89126 Regulation of BMP7 7 0.45 2.5 0.58
117 INT13929 Protein_catabolism of Th 3 1.00 0 0.58
118 INT126899 Regulation of SP1 5 0.43 2.53 0.57
119 INT40367 Positive_regulation of Gene_expression of LRP5 1 0.09 0 0.57
120 INT140984 Regulation of Ihh 5 0.54 2.81 0.56
121 INT243970 Phosphorylation of Tfap2a 2 0.25 0.56 0.56
122 INT314505 Positive_regulation of Protein_catabolism of TH 1 0.05 1.07 0.56
123 INT314499 Negative_regulation of Protein_catabolism of TH 1 0.04 1.06 0.54
124 INT165537 Negative_regulation of Bmp7 2 0.43 0.55 0.52
125 INT159214 Positive_regulation of Gene_expression of BMP7 6 0.46 2.16 0.51
126 INT89334 Negative_regulation of Binding of SP1 2 0.47 1.05 0.5
127 INT129620 Regulation of Gene_expression of Bmp7 3 0.42 3.2 0.47
128 INT200264 Localization of Sp3 1 0.62 0 0.47
129 INT253558 Negative_regulation of Binding of Sp3 1 0.39 1.09 0.46
130 INT6808 Localization of Zeb1 2 0.18 0 0.45
131 INT111304 Regulation of Gene_expression of TH 2 0.17 0.57 0.44
132 INT126896 Positive_regulation of Protein_catabolism of SP1 1 0.13 0.99 0.44
133 INT133315 Gene_expression of ZEB1 4 0.59 2.93 0.42
134 INT98969 Regulation of Binding of SP3 1 0.26 0 0.41
135 INT118460 Binding of Bmp7 3 0.46 1.3 0.4
136 INT90640 Positive_regulation of Negative_regulation of Th 2 0.40 0.58 0.39
137 INT89333 Negative_regulation of SP3 1 0.38 0.77 0.39
138 INT89335 Negative_regulation of Binding of SP3 1 0.38 0.77 0.39
139 INT126895 Protein_catabolism of SP1 3 0.96 3.59 0.38
140 INT314511 Positive_regulation of Binding of TH 1 0.04 0.68 0.38
141 INT98963 Positive_regulation of Binding of SP1 1 0.43 0 0.37
142 INT98960 Positive_regulation of Binding of SP3 1 0.67 0 0.37
143 INT166959 Positive_regulation of Positive_regulation of SP1 3 0.46 2.23 0.35
144 INT200265 Regulation of Sp3 2 0.37 0.25 0.34
145 INT349488 Positive_regulation of Localization of Th 1 0.30 0.96 0.34
146 INT166716 Negative_regulation of Ihh 3 0.43 0.67 0.33
147 INT285492 Transcription of Zeb1 1 0.17 0.61 0.33
148 INT285469 Positive_regulation of Transcription of Zeb1 1 0.12 0.61 0.33
149 INT196032 Positive_regulation of Gene_expression of Bmp7 10 0.17 1.31 0.31
150 INT277462 Regulation of Positive_regulation of Th 2 0.09 0.23 0.31
151 INT196024 Gene_expression of Bmp7 20 0.26 1.88 0.3
152 INT136460 Negative_regulation of Sp1 2 0.30 0.99 0.3
153 INT200276 Positive_regulation of Sp3 1 0.42 0.17 0.28
154 INT297804 Regulation of Lrp5 6 0.60 2.31 0.27
155 INT335875 Regulation of Lrp6 1 0.57 0.43 0.27
156 INT93215 Positive_regulation of Phosphorylation of Sp1 1 0.11 0.09 0.27
157 INT254427 Binding of Lrp5 10 0.48 5.43 0.26
158 INT149893 Positive_regulation of Gene_expression of Ihh 1 0.69 0.62 0.26
159 INT149892 Gene_expression of Ihh 1 0.77 0.61 0.26
160 INT40588 Regulation of Negative_regulation of Th 1 0.16 0.26 0.26
161 INT334543 Negative_regulation of Positive_regulation of LRP5 1 0.23 1.81 0.25
162 INT253556 Phosphorylation of Sp1 6 0.44 2.93 0.24
163 INT200251 Phosphorylation of Sp3 2 0.67 0.42 0.24
164 INT343976 Negative_regulation of Negative_regulation of TH 1 0.23 0.19 0.23
165 INT173655 Binding of LRP5 10 0.39 3.06 0.22
166 INT237448 Negative_regulation of Binding of TH 1 0.30 0.29 0.22
167 INT218762 Localization of ZEB1 2 0.65 0.09 0.2
168 INT136457 Negative_regulation of Negative_regulation of Sp1 1 0.30 0.65 0.2
169 INT115160 Gene_expression of CITED2 1 0.04 0.45 0.2
170 INT115153 Positive_regulation of Gene_expression of CITED2 1 0.02 0.45 0.2
171 INT253542 Positive_regulation of Phosphorylation of Sp1 1 0.27 1.16 0.2
172 INT218763 Regulation of ZEB1 1 0.39 0.32 0.2
173 INT149888 Localization of Ihh 1 0.75 0.77 0.2
174 INT136452 Negative_regulation of Negative_regulation of Sp3 1 0.28 0.65 0.2
175 INT140716 Negative_regulation of Protein_catabolism of Th 1 0.59 0 0.19
176 INT140717 Positive_regulation of Protein_catabolism of Th 1 0.47 0 0.19
177 INT254429 Negative_regulation of Lrp5 4 0.57 1.95 0.18
178 INT162939 Binding of Tfap2a 1 0.26 0.34 0.17
179 INT162940 Negative_regulation of Tfap2a 1 0.32 0.34 0.17
180 INT339267 Negative_regulation of BMP7 1 0.43 0.55 0.17
181 INT335861 Localization of Lrp6 1 0.69 0.54 0.17
182 INT162941 Negative_regulation of Binding of Tfap2a 1 0.32 0.34 0.17
183 INT185254 Gene_expression of Pax6 14 0.72 1.77 0.16
184 INT66986 Binding of Th 6 0.45 1.43 0.16
185 INT136454 Positive_regulation of Gene_expression of Sp3 1 0.33 0.44 0.16
186 INT178673 Positive_regulation of Gene_expression of SP1 1 0.08 0.14 0.16
187 INT118459 Regulation of Bmp7 3 0.43 0.25 0.15
188 INT201968 Positive_regulation of Bmp7 2 0.43 1.11 0.14
189 INT278241 Regulation of IHH 2 0.31 1.16 0.14
190 INT200261 Positive_regulation of Transcription of Sp3 1 0.42 0 0.13
191 INT200280 Transcription of Sp3 1 0.57 0 0.13
192 INT313420 Positive_regulation of Positive_regulation of Th 1 0.33 0.35 0.12
193 INT200268 Positive_regulation of Binding of Sp3 2 0.39 0.8 0.1
194 INT173632 Transcription of SP1 7 0.41 1.42 0.09
195 INT218760 Negative_regulation of ZEB1 4 0.38 1.38 0.09
196 INT322523 Regulation of Transcription of SP1 1 0.11 0.15 0.09
197 INT253546 Positive_regulation of Phosphorylation of Sp3 1 0.29 0.42 0.09
198 INT211005 Gene_expression of SP3 1 0.03 0.58 0.09
199 INT210805 Negative_regulation of IHH 2 0.42 0.74 0.08
200 INT355332 Localization of Bmp7 1 0.09 1.92 0.08
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