GO:0048608

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Name reproductive structure development
Categary Process
Go Slim No
Go Link GO:0048608
Unique Molecular Interactions 94
Total Molecular Interactions 133
Total Single Events 900
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for reproductive structure development. They are ordered first by their pain relevance and then by number of times they were reported for reproductive structure development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT281373 Tcf21 Regulation of Fig4 1 0.03 0.67 1.2
2 INT228681 Fkbp4 Negative_regulation of Trib3 1 0.00 0.57 1.2
3 INT281379 Tcf21 Regulation of FSCN1 1 0.01 0.66 1.19
4 INT316128 TCF21 Negative_regulation of Gene_expression of HLA-DRA 1 0.07 0.13 0.99
5 INT22726 Positive_regulation of Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
6 INT22725 Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
7 INT183176 Binding of FGFR2 and NUDT6 1 0.05 1.07 0.84
8 INT208372 Il13 Positive_regulation of Ahr 1 0.21 1.22 0.59
9 INT222246 Binding of Ccr2 and Tcf21 1 0.29 0.67 0.55
10 INT222249 Positive_regulation of Binding of Ccr2 and Tcf21 1 0.39 0.67 0.55
11 INT147575 Binding of Ahr and Cyp1a1 2 0.15 0.15 0.54
12 INT281124 Tcf21 Positive_regulation of Binding of Ddc 1 0.04 1.21 0.54
13 INT281129 Tcf21 Positive_regulation of Binding of Cd4 1 0.04 1.21 0.54
14 INT281152 Tcf21 Positive_regulation of Binding of ITIH4 1 0.03 1.21 0.54
15 INT55445 Positive_regulation of Ahr Regulation of Mme 1 0.23 0 0.53
16 INT281131 Tcf21 Positive_regulation of Rent1 1 0.00 1.19 0.53
17 INT147576 Positive_regulation of Ahr Positive_regulation of Gene_expression of Scrg1 1 0.00 0.17 0.52
18 INT281374 Tcf21 Positive_regulation of Gene_expression of Sds 1 0.03 0 0.51
19 INT222251 Negative_regulation of Binding of Cxcl10 and Tcf21 1 0.23 0.34 0.32
20 INT222247 Binding of Cxcl10 and Tcf21 1 0.20 0.34 0.32
21 INT296459 Binding of Dlg1 and Gria1 1 0.02 0.23 0.31
22 INT281127 Tcf21 Positive_regulation of Gene_expression of Cxcr4 1 0.08 0.42 0.3
23 INT274942 Binding of Dlg1 and Ephb6 1 0.05 0 0.25
24 INT279959 Tnfrsf1b Negative_regulation of Ahr 1 0.10 0.98 0.24
25 INT179186 Fcer2a Regulation of Positive_regulation of Ahr 1 0.05 1.23 0.23
26 INT20310 Binding of Hnf1a and Positive_regulation of Transcription of Cyp2e1 1 0.02 0 0.21
27 INT132680 HNF1A Positive_regulation of Gene_expression of UGT1A6 1 0.30 0.08 0.21
28 INT132679 HNF1A Regulation of Gene_expression of UGT1A6 1 0.16 0.08 0.21
29 INT188921 Binding of Pc and Ahr 1 0.12 0 0.19
30 INT188920 Pc Positive_regulation of Ahr 1 0.14 0 0.18
31 INT256985 Binding of Dlg1 and Cd81 1 0.39 0.2 0.17
32 INT134196 Ahr Regulation of Transcription of Cyp1a1 1 0.11 0.14 0.16
33 INT134202 Ahr Regulation of AHR 1 0.18 0.13 0.16
34 INT338419 Il13 Regulation of Positive_regulation of Ahr 1 0.04 0.54 0.13
35 INT336632 Ecm1 Regulation of Regulation of Ahr 1 0.03 0.61 0.11
36 INT325222 Il13 Regulation of Ahr 1 0.21 0.58 0.11
37 INT227061 Binding of Ahr and Alb 1 0.23 0.08 0.1
38 INT178434 Il6 Positive_regulation of Ar 1 0.01 0.93 0.08
39 INT343792 Binding of TCF21 and CORO7 1 0.01 0.51 0.07
40 INT303561 Binding of Fgf7 and Fgfr2 1 0.42 0.88 0.07
41 INT303560 Binding of Fgfr2 and Fgf22 1 0.41 0.89 0.07
42 INT303562 Binding of Fgf10 and Fgfr2 1 0.40 0.88 0.07
43 INT22568 Cyp1a1 Positive_regulation of Tcf21 1 0.04 0 0.06
44 INT22567 Cyp1a2 Positive_regulation of Tcf21 1 0.04 0 0.06
45 INT346752 Binding of Dlg1 and Gria1 1 0.02 0 0.06
46 INT250855 Binding of Fgfr2 and Fgf8 1 0.12 0.3 0.05
47 INT285388 Ahr Positive_regulation of Gene_expression of Cyp27b1 1 0.01 0.14 0.04
48 INT178441 Binding of Ar and Sra1 1 0.00 0.45 0.04
49 INT285386 Ahr Positive_regulation of Binding of Cyp27b1 1 0.01 0.14 0.04
50 INT178439 Binding of Ar and Src 1 0.01 0.44 0.04
51 INT178428 Regulation of Il6 Positive_regulation of Ar 1 0.01 0.47 0.04
52 INT279632 Positive_regulation of Binding of Ar and Nr4a1 1 0.01 0.86 0.03
53 INT303558 Binding of Fgfr2 and Dysf 1 0.01 0.44 0.03
54 INT197296 Ahr Regulation of Bhlha15 1 0.48 0.47 0.03
55 INT279634 Binding of Ar and Nr4a1 1 0.01 0.85 0.03
56 INT339404 Binding of Ar and Tymp 1 0.10 0.06 0
57 INT343744 mn Negative_regulation of Regulation of Wnt7a 1 0.01 0.1 0
58 INT284095 HNF1A Positive_regulation of TIMP3 1 0.38 2.3 0
59 INT284092 HNF1A Positive_regulation of FGD2 1 0.15 1.16 0
60 INT339403 Negative_regulation of Binding of Ar and Tymp 1 0.12 0 0
61 INT263726 Binding of Dlg1 and Dlg4 1 0.04 0 0
62 INT333842 Hnf1a Positive_regulation of Mir194-1 1 0.02 0.18 0
63 INT256988 Binding of Dlg1 and Rpe 1 0.06 0 0
64 INT340275 NFATC1 Positive_regulation of Binding of Ahr 1 0.10 0.51 0
65 INT263737 Binding of Dlg1 and Neto1 1 0.07 0 0
66 INT183091 Binding of FGF2 and FGFR2 1 0.03 0.79 0
67 INT284098 HNF1A Positive_regulation of SLC2A1 1 0.36 1.16 0
68 INT189127 Mch Positive_regulation of Ahr 1 0.18 0.29 0
69 INT197304 Ahr Regulation of Hes1 1 0.06 0.17 0
70 INT197295 Positive_regulation of Binding of Ahr and Cyp1a1 1 0.20 0 0
71 INT202675 Fgf10 Positive_regulation of Fgfr2 1 0.45 0.07 0
72 INT256981 Binding of Dlg1 and Slc9a3r1 1 0.22 0 0
73 INT279635 Ar Regulation of Abpe 1 0.01 1.55 0
74 INT198110 Ar Positive_regulation of Gene_expression of Aqp9 1 0.13 0 0
75 INT279633 Binding of Ar and Abpe 1 0.01 0.99 0
76 INT353194 ARNTL Regulation of Localization of Ahr 1 0.27 0.32 0
77 INT183089 Positive_regulation of Binding of FGF2 and FGFR2 1 0.04 0.4 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for reproductive structure development. They are ordered first by their pain relevance and then by number of times they were reported in reproductive structure development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT215353 Gene_expression of Tcf21 16 0.59 9.71 9.49
2 INT90603 Positive_regulation of Ahr 103 0.69 58.65 7.73
3 INT14166 Positive_regulation of Ahr 32 0.61 20.78 7.47
4 INT72834 Negative_regulation of Tcf21 10 0.58 5.8 4.84
5 INT14165 Negative_regulation of Ahr 14 0.51 8.35 4.17
6 INT22566 Positive_regulation of Tcf21 8 0.65 3.06 3.75
7 INT147572 Gene_expression of Ahr 73 0.75 38.99 3.15
8 INT47207 Negative_regulation of Ahr 25 0.52 16.11 3.02
9 INT281367 Regulation of Gene_expression of Tcf21 1 0.09 1.39 2.89
10 INT44661 Regulation of Ahr 15 0.45 12.69 2.79
11 INT281369 Negative_regulation of Gene_expression of Tcf21 1 0.08 1.4 2.44
12 INT228675 Binding of Fkbp4 1 0.01 1.14 2.28
13 INT55090 Positive_regulation of Wnt7a 13 0.37 2.25 2.2
14 INT90004 Gene_expression of TCF21 4 0.65 2.48 2.02
15 INT14167 Negative_regulation of Positive_regulation of Ahr 5 0.51 1.54 1.71
16 INT316162 Localization of TCF21 1 0.18 0.28 1.71
17 INT10598 Gene_expression of Ar 10 0.64 3.44 1.61
18 INT15969 Negative_regulation of Ar 11 0.43 2.77 1.59
19 INT90604 Positive_regulation of Positive_regulation of Ahr 8 0.45 3.52 1.45
20 INT54805 Regulation of Ahr 7 0.22 4.14 1.41
21 INT222228 Positive_regulation of Gene_expression of Tcf21 4 0.38 0.84 1.39
22 INT110485 Binding of Tcf21 2 0.36 0.76 1.37
23 INT68500 Regulation of Ar 6 0.27 4.16 1.32
24 INT3816 Gene_expression of Ahr 13 0.65 7.51 1.31
25 INT29693 Binding of Ahr 11 0.31 13.27 1.23
26 INT316154 Positive_regulation of TCF21 4 0.17 1.22 1.23
27 INT76890 Gene_expression of FGFR2 42 0.65 13.91 1.08
28 INT332771 Phosphorylation of Tcf21 1 0.09 0.21 1.07
29 INT332772 Positive_regulation of Phosphorylation of Tcf21 1 0.06 0.21 1.07
30 INT209218 Gene_expression of Dlg1 3 0.54 0.42 1.03
31 INT127647 Regulation of Wnt7a 3 0.07 1.28 1.01
32 INT45079 Binding of Ahr 21 0.44 10.07 1
33 INT24809 Positive_regulation of Fkbp4 3 0.40 1.57 1
34 INT102677 Negative_regulation of TCF21 2 0.41 0.22 0.89
35 INT183182 Negative_regulation of FGFR2 2 0.29 1.25 0.84
36 INT156529 Positive_regulation of Gene_expression of Ar 1 0.05 0.09 0.8
37 INT208367 Regulation of Localization of Ahr 1 0.30 1.6 0.67
38 INT208371 Localization of Ahr 2 0.50 1.9 0.66
39 INT28958 Negative_regulation of Wnt7a 3 0.45 0.49 0.65
40 INT158136 Binding of FGFR2 9 0.26 4.5 0.63
41 INT114942 Negative_regulation of Positive_regulation of Ahr 5 0.55 2.65 0.62
42 INT17493 Binding of Ar 14 0.48 3.62 0.6
43 INT281366 Regulation of Tcf21 1 0.09 0.23 0.59
44 INT49343 Positive_regulation of Ar 8 0.42 4.38 0.58
45 INT127648 Gene_expression of Wnt7a 2 0.13 1.11 0.56
46 INT316161 Negative_regulation of Gene_expression of TCF21 1 0.10 0.11 0.56
47 INT147571 Regulation of Binding of Ahr 1 0.26 0.15 0.54
48 INT163993 Gene_expression of Hnf1a 2 0.65 1.38 0.49
49 INT146778 Negative_regulation of Fgfr2 1 0.32 0.66 0.48
50 INT222229 Localization of Tcf21 1 0.57 0.45 0.45
51 INT94035 Transcription of Ahr 1 0.53 0.53 0.43
52 INT202626 Negative_regulation of Fgfr2 2 0.41 2.48 0.42
53 INT279958 Regulation of Regulation of Ahr 1 0.29 1.32 0.37
54 INT197286 Positive_regulation of Gene_expression of Ahr 10 0.67 9.78 0.36
55 INT17492 Negative_regulation of Binding of Ar 3 0.59 0.76 0.28
56 INT153731 Positive_regulation of Gene_expression of Ahr 2 0.32 2 0.28
57 INT319280 Positive_regulation of Dlg1 1 0.45 0.42 0.28
58 INT55443 Positive_regulation of Positive_regulation of Ahr 1 0.40 0 0.26
59 INT123520 Gene_expression of Ar 12 0.32 6.98 0.25
60 INT279628 Negative_regulation of Ar 5 0.04 6.1 0.25
61 INT176080 Gene_expression of Fgfr2 4 0.68 2.34 0.24
62 INT209224 Binding of Dlg1 3 0.13 0.22 0.23
63 INT112378 Negative_regulation of Regulation of Ar 1 0.43 0.19 0.23
64 INT223739 Binding of Fgfr2 3 0.30 0.94 0.22
65 INT20301 Positive_regulation of Binding of Hnf1a 1 0.02 0 0.21
66 INT199771 Localization of Ahr 8 0.70 4.86 0.2
67 INT20302 Binding of Hnf1a 1 0.02 0 0.2
68 INT55089 Positive_regulation of Positive_regulation of Wnt7a 2 0.27 0.06 0.16
69 INT134193 Regulation of Regulation of Ahr 1 0.12 0.14 0.16
70 INT289312 Phosphorylation of Ahr 1 0.03 0.86 0.15
71 INT49346 Transcription of Ar 3 0.63 0.8 0.14
72 INT123527 Negative_regulation of Gene_expression of Ar 2 0.10 0 0.14
73 INT294583 Negative_regulation of Gene_expression of Ahr 2 0.38 1.01 0.14
74 INT134194 Regulation of Gene_expression of Ahr 1 0.12 0.17 0.14
75 INT249107 Positive_regulation of HNF1A 1 0.49 0.2 0.13
76 INT99718 Positive_regulation of Gene_expression of FGFR2 9 0.49 4.47 0.12
77 INT243079 Regulation of Ar 3 0.08 1.22 0.12
78 INT197287 Regulation of Gene_expression of Ahr 5 0.45 1 0.11
79 INT162432 Positive_regulation of Ar 3 0.23 2.34 0.11
80 INT289311 Negative_regulation of Gene_expression of Ahr 1 0.02 1 0.09
81 INT162428 Localization of Ar 4 0.37 2.4 0.07
82 INT195858 Transcription of Ahr 2 0.69 1.33 0.07
83 INT195859 Positive_regulation of Transcription of Ahr 2 0.48 0.73 0.07
84 INT199780 Positive_regulation of Localization of Ahr 2 0.45 1.03 0.07
85 INT197288 Regulation of Positive_regulation of Ahr 1 0.59 0.45 0.07
86 INT162430 Negative_regulation of Positive_regulation of Ar 1 0.21 1.52 0.07
87 INT256975 Binding of Dlg1 7 0.36 0 0.06
88 INT243082 Binding of Ar 2 0.11 1.81 0.06
89 INT340266 Negative_regulation of Binding of Ahr 1 0.16 1.33 0.06
90 INT303546 Binding of Fgfr2 1 0.46 0.74 0.06
91 INT159426 Positive_regulation of Gene_expression of Wnt7a 1 0.10 0.51 0.05
92 INT294584 Negative_regulation of Negative_regulation of Ahr 1 0.38 0.56 0.04
93 INT213363 Regulation of Gene_expression of Ar 2 0.11 1.63 0.03
94 INT303525 Localization of Fgfr2 1 0.72 0.28 0.03
95 INT303547 Positive_regulation of Negative_regulation of Fgfr2 1 0.48 1.07 0.03
96 INT207729 Regulation of FGFR2 4 0.22 2.35 0
97 INT238985 Positive_regulation of FGFR2 3 0.49 1.19 0
98 INT123526 Positive_regulation of Gene_expression of Ar 2 0.11 1.29 0
99 INT205576 Positive_regulation of Hnf1a 2 0.49 1.1 0
100 INT99716 Transcription of FGFR2 2 0.34 0.22 0
101 INT305351 Positive_regulation of Regulation of FGFR2 2 0.37 0.97 0
102 INT99715 Regulation of Gene_expression of FGFR2 2 0.22 0.19 0
103 INT303555 Negative_regulation of Gene_expression of FGFR2 2 0.41 0.31 0
104 INT256961 Regulation of Gene_expression of Dlg1 1 0.33 0 0
105 INT202623 Negative_regulation of Gene_expression of Fgfr2 1 0.32 0 0
106 INT319036 Gene_expression of Fgfr2 1 0.48 0.08 0
107 INT182748 Positive_regulation of Transcription of Ar 1 0.46 0.43 0
108 INT240923 Regulation of Hnf1a 1 0.19 0.48 0
109 INT256978 Positive_regulation of Dlg1 1 0.34 0 0
110 INT266460 Positive_regulation of Binding of Wnt7a 1 0.04 0.06 0
111 INT287660 Negative_regulation of Negative_regulation of Ar 1 0.03 0.07 0
112 INT256952 Localization of Dlg1 1 0.55 0 0
113 INT335677 Regulation of Localization of Ar 1 0.00 0 0
114 INT146803 Negative_regulation of Gene_expression of Ar 1 0.16 0.08 0
115 INT266459 Binding of Wnt7a 1 0.03 0.06 0
116 INT293401 Regulation of Gene_expression of Ar 1 0.06 0.07 0
117 INT99717 Positive_regulation of Transcription of FGFR2 1 0.10 0.08 0
118 INT183117 Positive_regulation of Binding of FGFR2 1 0.09 0.81 0
119 INT256974 Gene_expression of Dlg1 1 0.50 0.08 0
120 INT343743 Negative_regulation of Regulation of Wnt7a 1 0.04 0.1 0
121 INT123516 Phosphorylation of Ar 1 0.19 0.07 0
122 INT205577 Positive_regulation of Gene_expression of Hnf1a 1 0.49 1.1 0
123 INT303524 Positive_regulation of Fgfr2 1 0.66 0.22 0
124 INT263679 Transcription of Dlg1 1 0.12 0.07 0
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