GO:0048639

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Name positive regulation of developmental growth
Categary Process
Go Slim No
Go Link GO:0048639
Unique Molecular Interactions 364
Total Molecular Interactions 529
Total Single Events 4516
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of developmental growth. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of developmental growth. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
2 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
3 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
4 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34
5 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33
6 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
7 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
8 INT278948 LEP Positive_regulation of Gene_expression of PTGER2 1 0.09 4.04 2.69
9 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
10 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
11 INT147652 PLCB1 Negative_regulation of Positive_regulation of TRPV1 1 0.27 0.92 1.62
12 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
13 INT290542 Crh Positive_regulation of Insr 1 0.02 0.36 1.36
14 INT117311 HP Positive_regulation of Lep 1 0.00 1.78 1.01
15 INT278962 LEP Positive_regulation of CPOX 1 0.05 1.33 1
16 INT278940 LEP Positive_regulation of Gene_expression of IL8 1 0.34 1.68 0.96
17 INT114068 Agtr2 Regulation of Gene_expression of Insr 1 0.15 0.95 0.79
18 INT130948 Amt Regulation of Gene_expression of LEP 1 0.00 1.04 0.78
19 INT130949 Amt Regulation of LEP 1 0.00 1.04 0.77
20 INT76499 Binding of Insr and Adora2a 1 0.08 0 0.76
21 INT278958 LEP Positive_regulation of IL1B 1 0.33 1.91 0.74
22 INT214163 Binding of Lep and Nts 1 0.04 0.21 0.74
23 INT290544 Negative_regulation of Crh Positive_regulation of Insr 1 0.01 0.3 0.72
24 INT89009 Lep Positive_regulation of Cck 2 0.67 0.43 0.69
25 INT278956 LEP Regulation of Gene_expression of IL8 1 0.30 1.11 0.69
26 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
27 INT278951 LEP Regulation of Gene_expression of PTGER2 1 0.07 1.11 0.69
28 INT8980 Gal Regulation of PLCB1 1 0.18 0.13 0.68
29 INT278965 LEP Positive_regulation of Gene_expression of NOS2 2 0.29 2.12 0.66
30 INT290549 Gopc Positive_regulation of Positive_regulation of Insr 1 0.01 0.06 0.65
31 INT290545 Crh Positive_regulation of Positive_regulation of Insr 1 0.02 0.06 0.64
32 INT290550 Gopc Positive_regulation of Insr 1 0.01 0.06 0.64
33 INT290540 Positive_regulation of Crh Positive_regulation of Insr 1 0.02 0.06 0.64
34 INT46493 Binding of Insr and Oxt 1 0.14 0 0.62
35 INT323773 Binding of Il6 and Lep 1 0.29 3.54 0.6
36 INT276217 Pdk1 Positive_regulation of Positive_regulation of Insr 1 0.05 0.1 0.6
37 INT89010 Arc Positive_regulation of Insr 1 0.08 0.86 0.59
38 INT89012 DST Positive_regulation of Insr 1 0.01 0.86 0.59
39 INT349083 Binding of Lep and Rtn1 1 0.09 1.68 0.57
40 INT91339 Binding of Lep and Cck 1 0.28 0.34 0.56
41 INT113162 Lep Positive_regulation of Positive_regulation of Insrr 1 0.03 0 0.55
42 INT253834 Cck Regulation of Lep 1 0.19 0.23 0.55
43 INT204087 IL1B Positive_regulation of Gene_expression of LEP 1 0.09 2.6 0.54
44 INT214160 Binding of Lep and Mc4r 1 0.29 1.31 0.53
45 INT214143 Binding of Lep and Pomc 1 0.27 1.2 0.53
46 INT114070 Agtr2 Positive_regulation of Gene_expression of Insr 1 0.13 0.34 0.52
47 INT162890 Negative_regulation of Binding of LEP and Tnf 1 0.03 0.49 0.48
48 INT162889 Binding of LEP and Tnf 1 0.03 0.49 0.48
49 INT114065 Akt1 Regulation of Gene_expression of Insr 1 0.13 0.28 0.46
50 INT37599 Ace Regulation of Localization of Insr 1 0.18 0 0.46
51 INT132509 Binding of LEP and Cck 1 0.13 0.16 0.45
52 INT323880 Binding of BMI1 and LEP 1 0.02 3.97 0.41
53 INT83171 Cck Regulation of Lep 1 0.30 0.09 0.4
54 INT97395 Lep Positive_regulation of Stat3 1 0.67 0.42 0.4
55 INT114067 Ace Regulation of Insr 1 0.09 0.31 0.39
56 INT143747 Binding of IL6 and LEP 2 0.04 4.05 0.38
57 INT300488 Binding of CRP and LEP 1 0.46 2.03 0.37
58 INT226785 Angpt2 Positive_regulation of Localization of Lep 1 0.01 1.65 0.36
59 INT278966 MAPK14 Positive_regulation of Gene_expression of LEP 1 0.16 0.62 0.36
60 INT278949 JAK3 Positive_regulation of Gene_expression of LEP 1 0.42 0.63 0.36
61 INT336573 Ptpn2 Regulation of INSR 1 0.00 1.36 0.36
62 INT242403 INSR Positive_regulation of Gene_expression of Bdkrb1 1 0.45 0.88 0.35
63 INT323885 LEP Regulation of Gene_expression of NOS2 1 0.26 1.07 0.35
64 INT213484 Binding of Lep and Pik3c3 1 0.01 0 0.35
65 INT155166 Binding of C2 and C3 1 0.40 0 0.34
66 INT207184 Binding of Adipoq and Lep 1 0.25 2.45 0.33
67 INT323870 LEP Regulation of Gene_expression of MMP13 1 0.21 1.76 0.33
68 INT303993 Lep Positive_regulation of Gene_expression of IL2 1 0.15 0.24 0.33
69 INT105873 Ins1 Negative_regulation of Positive_regulation of Lep 1 0.27 0.67 0.31
70 INT278942 LEP Regulation of IL6 1 0.29 0.61 0.31
71 INT278939 LEP Regulation of IL8 1 0.13 0.61 0.31
72 INT213485 Lep Positive_regulation of Localization of Grin2a 1 0.19 0 0.31
73 INT296459 Binding of Dlg1 and Gria1 1 0.02 0.23 0.31
74 INT278969 LEP Regulation of PTGER2 1 0.03 0.6 0.31
75 INT105874 Lep Negative_regulation of Positive_regulation of Ins1 1 0.27 0.67 0.31
76 INT226989 Lias Regulation of Gene_expression of Lep 1 0.10 0.91 0.3
77 INT278961 IL6 Regulation of Gene_expression of LEP 1 0.29 0.89 0.3
78 INT303983 Lep Positive_regulation of CXCL10 1 0.06 0.31 0.29
79 INT333886 Binding of Lep and Positive_regulation of Gene_expression of Nos2 1 0.39 0.73 0.29
80 INT303998 Lep Positive_regulation of Localization of IL1RAPL1 1 0.04 0.31 0.29
81 INT333887 Binding of Lep and Positive_regulation of Gene_expression of Il1 1 0.17 0.73 0.29
82 INT303995 Lep Positive_regulation of PSME1 1 0.09 0.32 0.29
83 INT303984 Lep Positive_regulation of Gene_expression of IL8 1 0.06 0.85 0.28
84 INT100531 Cck Positive_regulation of Lep 1 0.70 0.15 0.26
85 INT228611 Binding of DNMT3B and LEP 1 0.04 0 0.25
86 INT218732 Lep Regulation of Gene_expression of Trh 1 0.19 0.18 0.25
87 INT274942 Binding of Dlg1 and Ephb6 1 0.05 0 0.25
88 INT41406 Binding of Insr and Thtpa 1 0.05 0 0.25
89 INT157957 Ppyr1 Negative_regulation of Phosphorylation of PLCB1 1 0.00 0.24 0.24
90 INT125748 Binding of LEP and Gh 1 0.00 0.52 0.24
91 INT118857 PLCB1 Regulation of Phosphorylation of SRC 1 0.01 0.15 0.24
92 INT238260 Positive_regulation of pma Negative_regulation of Transcription of C3 1 0.02 0.12 0.23
93 INT306795 Binding of LEP and SFTPD 1 0.08 1.13 0.23
94 INT303988 Lep Positive_regulation of Gene_expression of ISYNA1 1 0.06 0.55 0.23
95 INT323883 BMI1 Regulation of LEP 1 0.02 2.39 0.23
96 INT89158 Grpr Positive_regulation of Localization of Insr 1 0.02 0 0.23
97 INT102937 Gnrh1 Positive_regulation of Gene_expression of Lep 1 0.50 0 0.22
98 INT110653 Lep Regulation of Localization of Cck 1 0.06 0.22 0.22
99 INT269180 LEP Positive_regulation of Localization of TNF 1 0.01 0.99 0.21
100 INT323873 LEP Regulation of Gene_expression of TIMP2 1 0.31 0.63 0.21
101 INT207185 Binding of Bmi1 and Lep 1 0.01 1.7 0.21
102 INT222482 Lep Positive_regulation of Localization of Gh1 1 0.02 1.02 0.2
103 INT304001 Lep Negative_regulation of ICAM3 1 0.07 0.35 0.2
104 INT333889 Lep Regulation of Col7a1 1 0.04 0.41 0.2
105 INT303979 Lep Positive_regulation of ITGB2 1 0.11 0.35 0.2
106 INT256576 Lep Regulation of Localization of Ins1 1 0.57 2.08 0.2
107 INT303991 Lep Negative_regulation of SELL 1 0.04 0.35 0.2
108 INT217661 LEP Positive_regulation of INS 2 0.25 1.85 0.19
109 INT327814 Rab8a Regulation of Regulation of Lep 1 0.01 0.15 0.19
110 INT327813 Rab8a Regulation of Lep 1 0.01 0.15 0.19
111 INT303964 Lep Positive_regulation of Icam1 1 0.24 0.35 0.19
112 INT333888 Lep Regulation of Localization of GAG 1 0.68 0.38 0.19
113 INT181082 Binding of C3 and C3ar1 1 0.03 1.31 0.19
114 INT279507 Serping1 Negative_regulation of Gene_expression of C3 1 0.03 1.12 0.19
115 INT279500 Serping1 Negative_regulation of Transcription of C3 1 0.03 1.12 0.19
116 INT214170 Binding of DST and Lep 1 0.02 0.17 0.18
117 INT303981 Lep Positive_regulation of Localization of CXCL1 1 0.02 0.34 0.18
118 INT226988 Lias Positive_regulation of Localization of Lep 1 0.08 0.3 0.17
119 INT303967 Lep Positive_regulation of Gene_expression of Icam1 1 0.24 0.58 0.16
120 INT344590 Binding of IFN1@ and C3 1 0.32 0.3 0.16
121 INT303980 Lep Positive_regulation of Transcription of IL2 1 0.10 0.24 0.16
122 INT217667 LEP Negative_regulation of Localization of INS 1 0.15 1.18 0.14
123 INT217664 LEP Negative_regulation of INS 1 0.15 1.18 0.14
124 INT323877 LEP Positive_regulation of SOAT1 1 0.20 1.26 0.14
125 INT139975 Binding of LEP and Prl 1 0.02 0.49 0.13
126 INT59808 Binding of AGT and PLCB1 1 0.02 0 0.13
127 INT328060 LEP Positive_regulation of FAAH 1 0.06 0.7 0.13
128 INT346714 LEP Regulation of GALP 1 0.06 0.08 0.13
129 INT59809 AGT Positive_regulation of PLCB1 1 0.03 0 0.13
130 INT59807 ADRA1D Positive_regulation of PLCB1 1 0.33 0 0.13
131 INT81179 LEP Regulation of Localization of GH1 1 0.11 0.91 0.12
132 INT214141 Binding of Lep and Lepr 1 0.32 0.82 0.12
133 INT150532 LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12
134 INT150533 Positive_regulation of LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12
135 INT164746 Binding of LEP and Adipoq 1 0.07 0.69 0.12
136 INT323871 LEP Regulation of Gene_expression of IGF1 1 0.14 1.19 0.11
137 INT270746 INS Regulation of LEP 1 0.07 0.72 0.11
138 INT294742 Lep Positive_regulation of Localization of Icam1 1 0.15 0.48 0.11
139 INT163817 Lep Positive_regulation of Phosphorylation of Akt1 1 0.33 0.31 0.11
140 INT220905 Cfb Positive_regulation of C3 1 0.06 0.91 0.11
141 INT222472 Lep Positive_regulation of Localization of Cartpt 1 0.05 0 0.11
142 INT303989 Lep Positive_regulation of IL12A 1 0.05 0.39 0.11
143 INT303966 Lep Regulation of Il1 2 0.09 0.41 0.1
144 INT303990 Binding of Lep and Positive_regulation of Gene_expression of LPL 1 0.03 0.35 0.1
145 INT323879 LEP Regulation of SOAT1 1 0.15 1.15 0.1
146 INT204086 TNF Positive_regulation of Gene_expression of LEP 1 0.48 0.74 0.1
147 INT304000 Lep Negative_regulation of Positive_regulation of CASP8 1 0.04 0.25 0.1
148 INT123864 Lep Positive_regulation of Positive_regulation of Cck 1 0.45 0.1 0.09
149 INT242324 Lep Regulation of Gene_expression of Ucp1 1 0.58 1.47 0.09
150 INT142418 Lep Positive_regulation of Gene_expression of Ghrl 1 0.48 1.66 0.09
151 INT306794 Binding of LEP and COPD 1 0.15 3.94 0.09
152 INT213482 Lep Positive_regulation of Mapk1 1 0.06 0.08 0.09
153 INT300486 LEP Positive_regulation of ROS1 1 0.15 0.91 0.09
154 INT349660 Binding of INSR and PYCARD 1 0.01 0 0.09
155 INT323868 LEP Regulation of Transcription of COL1A2 1 0.10 0.98 0.09
156 INT214752 EDNRA Positive_regulation of PLCB1 1 0.02 0 0.08
157 INT45452 Binding of C2 and C3 1 0.34 0.08 0.08
158 INT325059 Insr Positive_regulation of Ang 1 0.02 1.4 0.08
159 INT115258 Insr Positive_regulation of Phosphorylation of Irs1 1 0.19 0.26 0.08
160 INT222545 Lep Negative_regulation of Nmb 1 0.04 0.52 0.08
161 INT123866 Lep Negative_regulation of Olfr544 1 0.00 0.09 0.08
162 INT303999 Lep Positive_regulation of Gene_expression of ITGA2 1 0.06 0.29 0.08
163 INT332287 LEP Positive_regulation of Phosphorylation of IRS1 1 0.20 1.48 0.08
164 INT323881 BMI1 Regulation of Gene_expression of LEP 1 0.03 1.09 0.08
165 INT323876 LEP Regulation of COL1A2 1 0.10 0.86 0.08
166 INT115933 U Regulation of PLCB1 1 0.00 0.3 0.08
167 INT268325 Lep Positive_regulation of Ptgs2 1 0.09 0.39 0.08
168 INT303970 Lep Positive_regulation of Gene_expression of Itga2 1 0.09 0.29 0.08
169 INT294743 Lep Positive_regulation of Transcription of Il6 1 0.18 0.42 0.07
170 INT294740 Lep Positive_regulation of Transcription of Ccl2 1 0.08 0.42 0.07
171 INT323872 LEP Positive_regulation of Gene_expression of IGF1 1 0.35 0.77 0.07
172 INT303997 IL1RL1 Positive_regulation of Lep 1 0.01 0.2 0.07
173 INT17920 Penk Positive_regulation of Insr 1 0.05 0.14 0.06
174 INT214153 Lep Regulation of Transcription of Nucb2 1 0.35 0.15 0.06
175 INT253377 Lep Negative_regulation of Phosphorylation of Prkaa2 1 0.24 1.24 0.06
176 INT323878 Binding of LEP and MMP13 1 0.17 0.77 0.05
177 INT267152 Binding of LEP and DDX12P 1 0.00 0.69 0.05
178 INT184123 Socs3 Positive_regulation of Protein_catabolism of Insr 1 0.03 0.41 0.05
179 INT267157 LEP Positive_regulation of ADIPOQ 1 0.10 0.51 0.05
180 INT325060 Binding of Insr and Hand1 1 0.00 0.16 0.05
181 INT345965 Binding of Lep and al44 1 0.01 1.43 0.05
182 INT314135 Negative_regulation of Nos2 Positive_regulation of Lep 1 0.52 0.44 0.05
183 INT327821 GPRC6A Regulation of Gene_expression of Lep 1 0.00 0.5 0.05
184 INT327822 INCENP Regulation of Gene_expression of Lep 1 0.00 0.5 0.05
185 INT267153 Binding of LEP and SUGT1 1 0.02 0.69 0.05
186 INT184085 Socs1 Positive_regulation of Protein_catabolism of Insr 1 0.04 0.41 0.05
187 INT253376 Lep Regulation of Mtor 1 0.17 0.08 0.04
188 INT303986 Lep Positive_regulation of Gene_expression of TNF 1 0.49 0.29 0.04
189 INT332684 Binding of Edn1 and Lep 1 0.09 1.11 0.04
190 INT253363 Lep Regulation of Prkaa2 1 0.15 0.08 0.04
191 INT222534 Gnrh1 Positive_regulation of Localization of Lep 1 0.07 0 0.04
192 INT342170 Insr Regulation of Localization of Cd320 1 0.08 0.92 0.04
193 INT303996 Lep Positive_regulation of Gene_expression of IL12A 1 0.08 0.29 0.04
194 INT303965 Lep Positive_regulation of Gene_expression of Il6 1 0.07 0.29 0.04
195 INT225800 Binding of Insr and Enpp1 1 0.05 0.67 0.04
196 INT249046 Binding of LEP and ARID1B 1 0.01 1.3 0.03
197 INT231438 LEP Positive_regulation of Negative_regulation of NOS3 1 0.09 0.32 0.03
198 INT253374 Lep Positive_regulation of Phosphorylation of Eif4ebp1 1 0.04 0.16 0.03
199 INT253375 Lep Positive_regulation of Phosphorylation of Rps6kb1 1 0.41 0.16 0.03
200 INT253414 Lep Negative_regulation of BCL2A1 1 0.16 0 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of developmental growth. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of developmental growth. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
2 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5
3 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59
4 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31
5 INT8691 Localization of Insr 85 0.80 9.27 30.32
6 INT5300 Regulation of Insr 54 0.60 11.33 29.26
7 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12
8 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76
9 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22
10 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77
11 INT75908 Regulation of LEP 77 0.60 60.16 15.19
12 INT14768 Negative_regulation of Positive_regulation of Insr 16 0.56 5.51 13.59
13 INT73641 Regulation of Lep 45 0.62 26.2 12.59
14 INT110988 Gene_expression of Insr 58 0.42 42.12 12.18
15 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17
16 INT82079 Positive_regulation of Lep 79 0.70 40 11.07
17 INT101481 Positive_regulation of Lep 81 0.69 62.59 9.95
18 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38
19 INT82082 Localization of Lep 63 0.81 26.41 8.56
20 INT75907 Binding of LEP 53 0.46 46.65 8.44
21 INT178198 Gene_expression of C3 62 0.78 39.5 7.69
22 INT1120 Gene_expression of C3 33 0.67 22.86 7.56
23 INT30920 Positive_regulation of Gene_expression of Insr 14 0.66 2.91 7.32
24 INT36405 Positive_regulation of Insr 26 0.66 24.5 7.24
25 INT24622 Positive_regulation of Localization of Insr 15 0.69 0.32 6.85
26 INT32611 Phosphorylation of Insr 13 0.80 4.18 5.77
27 INT146594 Negative_regulation of Gene_expression of LEP 25 0.42 18.88 5.71
28 INT101482 Negative_regulation of Lep 53 0.54 33.59 5.65
29 INT14769 Positive_regulation of Positive_regulation of Insr 10 0.43 2.66 5.55
30 INT65356 Localization of LEP 46 0.79 41.17 5.43
31 INT91338 Binding of Lep 31 0.48 26.86 5.39
32 INT102935 Regulation of Lep 31 0.60 18.47 5.24
33 INT114058 Negative_regulation of Gene_expression of Insr 13 0.31 9.23 4.97
34 INT10115 Gene_expression of INSR 31 0.75 11.98 4.86
35 INT51392 Negative_regulation of Insr 18 0.27 14.75 4.84
36 INT24620 Negative_regulation of Gene_expression of Insr 14 0.39 6.98 4.61
37 INT97391 Binding of Lep 18 0.48 8.97 4.47
38 INT51084 Binding of Insr 13 0.30 4.25 4.23
39 INT83035 Binding of INSR 16 0.47 9.29 4.11
40 INT163581 Localization of Lep 27 0.79 18.99 4.08
41 INT179542 Positive_regulation of C3 27 0.52 19.39 3.83
42 INT119606 Regulation of Gene_expression of LEP 17 0.45 17.96 3.75
43 INT174054 Positive_regulation of Gene_expression of Lep 25 0.69 21.3 3.72
44 INT82077 Positive_regulation of Gene_expression of Lep 32 0.70 17.9 3.5
45 INT10116 Localization of INSR 11 0.57 5.43 3.48
46 INT14060 Negative_regulation of Negative_regulation of Insr 6 0.53 3.53 3.44
47 INT124736 Positive_regulation of Gene_expression of Insr 6 0.31 7.55 3.12
48 INT184365 Negative_regulation of C3 19 0.43 13.86 2.89
49 INT9460 Positive_regulation of C3 6 0.69 3.96 2.81
50 INT97443 Positive_regulation of Positive_regulation of LEP 13 0.50 11.91 2.65
51 INT155160 Binding of C3 20 0.47 7.77 2.61
52 INT23527 Negative_regulation of Localization of Insr 10 0.39 2.58 2.5
53 INT103487 Positive_regulation of Positive_regulation of Lep 9 0.67 4.08 2.38
54 INT59818 Negative_regulation of PLCB1 7 0.57 2.24 2.28
55 INT24621 Regulation of Gene_expression of Insr 9 0.42 2.68 2.18
56 INT82081 Regulation of Gene_expression of Lep 11 0.53 7.78 2.12
57 INT31006 Regulation of Localization of Insr 7 0.50 0.2 2.05
58 INT83392 Transcription of Lep 6 0.54 5.07 2.04
59 INT114059 Localization of Insr 10 0.46 3.49 1.87
60 INT82083 Negative_regulation of Gene_expression of Lep 12 0.56 8.07 1.75
61 INT218303 Protein_catabolism of INSR 3 0.29 0.67 1.73
62 INT232645 Transcription of INSR 2 0.09 1.19 1.71
63 INT114061 Regulation of Gene_expression of Insr 4 0.27 2.03 1.56
64 INT19342 Regulation of Insr 12 0.24 6.11 1.54
65 INT182037 Localization of C3 10 0.68 6.69 1.54
66 INT214115 Regulation of Gene_expression of Lep 9 0.61 7.37 1.44
67 INT10885 Negative_regulation of C3 9 0.38 11.86 1.35
68 INT179539 Positive_regulation of Gene_expression of C3 9 0.70 5.98 1.32
69 INT124738 Negative_regulation of Positive_regulation of Insr 5 0.23 3.73 1.24
70 INT148212 Negative_regulation of Gene_expression of C3 2 0.43 5.47 1.24
71 INT10117 Positive_regulation of INSR 10 0.43 4.71 1.22
72 INT59815 Positive_regulation of PLCB1 9 0.67 1.12 1.22
73 INT167270 Negative_regulation of Gene_expression of Lep 13 0.55 5.48 1.19
74 INT213465 Transcription of Lep 4 0.68 2.11 1.15
75 INT93055 Regulation of C3 4 0.40 1.81 1.12
76 INT253813 Regulation of Negative_regulation of Lep 2 0.45 1.01 1.12
77 INT106339 Positive_regulation of Phosphorylation of Insr 1 0.49 0 1.12
78 INT82084 Positive_regulation of Localization of Lep 11 0.70 4.65 1.11
79 INT32354 Negative_regulation of Regulation of Insr 3 0.33 0.13 1.08
80 INT209218 Gene_expression of Dlg1 3 0.54 0.42 1.03
81 INT238250 Regulation of Gene_expression of C3 2 0.27 2.16 0.98
82 INT171382 Phosphorylation of Insr 6 0.51 3.41 0.94
83 INT41911 Regulation of Positive_regulation of Insr 2 0.21 0.32 0.88
84 INT111668 Binding of C3 4 0.36 3.84 0.87
85 INT171376 Positive_regulation of Phosphorylation of Insr 3 0.31 3.05 0.86
86 INT117308 Negative_regulation of Localization of Lep 3 0.59 2.16 0.86
87 INT91908 Regulation of Negative_regulation of Insr 1 0.03 0.81 0.86
88 INT333883 Positive_regulation of Positive_regulation of Lep 2 0.46 1.06 0.83
89 INT144759 Regulation of Gene_expression of INSR 2 0.44 3.09 0.77
90 INT82080 Regulation of Localization of Lep 2 0.45 1.36 0.76
91 INT156533 Transcription of LEP 9 0.69 4.35 0.74
92 INT213471 Positive_regulation of Localization of Lep 4 0.48 2.65 0.74
93 INT179530 Transcription of C3 4 0.69 2.59 0.7
94 INT117392 Binding of Insr 8 0.23 4.88 0.68
95 INT171366 Positive_regulation of Localization of Insr 3 0.18 0.63 0.66
96 INT59817 Gene_expression of PLCB1 4 0.75 0.73 0.65
97 INT18445 Regulation of Transcription of Insr 1 0.12 0.84 0.63
98 INT18446 Transcription of Insr 2 0.18 0.84 0.62
99 INT101484 Regulation of Positive_regulation of Lep 3 0.45 1.68 0.61
100 INT345957 Positive_regulation of Binding of Lep 2 0.38 2.03 0.6
101 INT83391 Negative_regulation of Transcription of Lep 1 0.43 0.34 0.6
102 INT306798 Protein_catabolism of LEP 1 0.65 2.45 0.58
103 INT308979 Regulation of Localization of Insr 1 0.24 0.44 0.53
104 INT45447 Positive_regulation of Gene_expression of C3 2 0.42 0.9 0.49
105 INT82819 Negative_regulation of Negative_regulation of LEP 3 0.56 2.22 0.46
106 INT157955 Phosphorylation of PLCB1 1 0.01 0.46 0.46
107 INT220886 Regulation of C3 2 0.36 1.04 0.43
108 INT102934 Positive_regulation of Regulation of Lep 2 0.50 0.55 0.42
109 INT241407 Phosphorylation of C3 2 0.24 0.16 0.42
110 INT323765 Negative_regulation of Binding of Lep 1 0.37 0.91 0.42
111 INT187726 Positive_regulation of Localization of LEP 5 0.50 5.31 0.41
112 INT238253 Localization of C3 1 0.37 1.76 0.41
113 INT114062 Negative_regulation of Localization of Insr 1 0.19 0.31 0.39
114 INT144755 Negative_regulation of INSR 5 0.41 2.09 0.36
115 INT74604 Negative_regulation of Gene_expression of PLCB1 1 0.41 0.25 0.35
116 INT179532 Protein_catabolism of C3 5 0.26 1.61 0.34
117 INT1121 Protein_catabolism of C3 1 0.96 1.8 0.34
118 INT83030 Positive_regulation of Binding of INSR 2 0.49 2.35 0.31
119 INT59816 Positive_regulation of Gene_expression of PLCB1 2 0.49 0.22 0.31
120 INT303962 Phosphorylation of Lep 2 0.80 5.2 0.31
121 INT213467 Negative_regulation of Localization of Lep 2 0.40 1.11 0.31
122 INT156534 Positive_regulation of Transcription of LEP 1 0.14 0.34 0.3
123 INT141781 Positive_regulation of Negative_regulation of LEP 1 0.46 0.37 0.29
124 INT235857 Binding of PLCB1 1 0.36 0.35 0.29
125 INT319280 Positive_regulation of Dlg1 1 0.45 0.42 0.28
126 INT278530 Regulation of Positive_regulation of Insr 1 0.01 1.96 0.28
127 INT124735 Positive_regulation of Positive_regulation of Insr 1 0.08 0 0.25
128 INT115253 Negative_regulation of Phosphorylation of Insr 1 0.27 0.56 0.25
129 INT209224 Binding of Dlg1 3 0.13 0.22 0.23
130 INT150977 Regulation of Regulation of LEP 3 0.37 2.07 0.23
131 INT238247 Transcription of C3 1 0.43 0.12 0.23
132 INT238248 Negative_regulation of Transcription of C3 1 0.26 0.12 0.23
133 INT142417 Positive_regulation of Transcription of Lep 2 0.52 2.63 0.22
134 INT157956 Regulation of Phosphorylation of PLCB1 1 0.00 0.22 0.22
135 INT181039 Negative_regulation of Positive_regulation of C3 1 0.32 1.42 0.22
136 INT236354 Negative_regulation of Negative_regulation of C3 2 0.25 2.19 0.21
137 INT245266 Positive_regulation of Localization of C3 1 0.23 1.11 0.21
138 INT181041 Negative_regulation of Gene_expression of C3 1 0.32 1.37 0.2
139 INT74602 Negative_regulation of Positive_regulation of PLCB1 1 0.41 0.25 0.19
140 INT163816 Phosphorylation of Lep 2 0.63 2.2 0.17
141 INT333880 Protein_catabolism of Lep 1 0.65 0.34 0.17
142 INT220895 Negative_regulation of Binding of C3 3 0.28 0.95 0.16
143 INT157134 Regulation of Localization of LEP 1 0.09 0.5 0.16
144 INT333882 Regulation of Binding of Lep 1 0.45 0.07 0.16
145 INT204088 Regulation of Negative_regulation of LEP 1 0.59 1.16 0.16
146 INT300489 Negative_regulation of Binding of LEP 1 0.41 1.12 0.15
147 INT278979 Negative_regulation of Positive_regulation of LEP 2 0.40 0.81 0.14
148 INT187723 Regulation of Positive_regulation of LEP 3 0.42 2.29 0.13
149 INT323898 Regulation of Phosphorylation of LEP 1 0.42 1.25 0.13
150 INT323895 Phosphorylation of LEP 1 0.76 1.23 0.13
151 INT157241 Negative_regulation of Localization of LEP 5 0.56 2.1 0.12
152 INT163815 Negative_regulation of Negative_regulation of Lep 1 0.43 0.32 0.12
153 INT92634 Negative_regulation of Binding of Insr 1 0.25 0.08 0.12
154 INT181582 Phosphorylation of C3 1 0.34 1.2 0.12
155 INT308981 Positive_regulation of Negative_regulation of Insr 1 0.27 0.95 0.11
156 INT323945 Positive_regulation of Binding of Insr 1 0.08 0.94 0.11
157 INT226984 Regulation of Transcription of Lep 1 0.27 0.3 0.11
158 INT1122 Positive_regulation of Protein_catabolism of C3 1 0.45 0.45 0.09
159 INT59820 Regulation of Gene_expression of PLCB1 1 0.44 0 0.09
160 INT115930 Regulation of PLCB1 1 0.02 0.29 0.08
161 INT187729 Positive_regulation of Binding of LEP 1 0.18 0.3 0.08
162 INT213475 Negative_regulation of Positive_regulation of Lep 2 0.40 1.79 0.07
163 INT74606 Regulation of Negative_regulation of PLCB1 1 0.44 0.19 0.07
164 INT213466 Negative_regulation of Regulation of Lep 1 0.41 0 0.06
165 INT334858 Positive_regulation of Phosphorylation of C3 1 0.13 0 0.06
166 INT184013 Protein_catabolism of Insr 1 0.05 0.4 0.04
167 INT59814 Positive_regulation of Negative_regulation of PLCB1 1 0.45 0 0.04
168 INT247840 Regulation of Gene_expression of C3 1 0.45 0.13 0.04
169 INT117362 Positive_regulation of Positive_regulation of INSR 1 0.22 0.1 0.03
170 INT334843 Negative_regulation of Phosphorylation of C3 1 0.15 0 0.03
171 INT235634 Phosphorylation of INSR 24 0.70 3.64 0
172 INT215947 Positive_regulation of Gene_expression of INSR 2 0.14 0.25 0
173 INT253406 Negative_regulation of Positive_regulation of Lep 2 0.41 0.74 0
174 INT150408 Regulation of Regulation of Lep 1 0.27 0 0
175 INT305226 Negative_regulation of Phosphorylation of Lep 1 0.42 1.89 0
176 INT305239 Positive_regulation of Phosphorylation of Lep 1 0.43 1.09 0
177 INT144758 Negative_regulation of Negative_regulation of INSR 1 0.41 0 0
178 INT235628 Negative_regulation of Phosphorylation of INSR 1 0.16 0.25 0
179 INT230481 Positive_regulation of Regulation of Insr 1 0.01 0.24 0
180 INT144756 Positive_regulation of Negative_regulation of INSR 1 0.49 0 0
181 INT332954 Regulation of Transcription of Lep 1 0.11 1.4 0
182 INT144757 Negative_regulation of Gene_expression of INSR 1 0.41 0 0
183 INT157243 Negative_regulation of Transcription of LEP 1 0.02 0.09 0
184 INT279446 Regulation of Binding of C3 1 0.18 0 0
185 INT174279 Positive_regulation of Negative_regulation of Lep 1 0.46 0.16 0
186 INT309421 Positive_regulation of Regulation of Lep 1 0.41 0.61 0
187 INT288213 Positive_regulation of Negative_regulation of Lep 1 0.47 0.06 0
188 INT263679 Transcription of Dlg1 1 0.12 0.07 0
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