GO:0048643

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Name positive regulation of skeletal muscle tissue development
Categary Process
Go Slim No
Go Link GO:0048643
Unique Molecular Interactions 84
Total Molecular Interactions 136
Total Single Events 784
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of skeletal muscle tissue development. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of skeletal muscle tissue development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
2 INT240909 Hmgcr Regulation of Gene_expression of Sod1 1 0.03 0.53 0.14
3 INT238628 Mef2c Regulation of Gene_expression of Arc 1 0.09 0.16 0.08
4 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
5 INT238625 Mef2c Regulation of Gene_expression of Syngap1 1 0.10 0.16 0.08
6 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
7 INT298349 HES3 Positive_regulation of Shh 1 0.12 0.14 0.07
8 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
9 INT329429 Binding of Col7a1 and Hmgcr 1 0.01 0.28 0.06
10 INT239320 Eef1a2 Negative_regulation of Hmgcr 1 0.06 0.89 0.04
11 INT213563 Binding of Ctnnd2 and Shh 1 0.27 0.09 0.04
12 INT270459 Binding of Shh and Gli1 1 0.02 0.65 0.04
13 INT352014 Shh Positive_regulation of Gene_expression of Pax1 1 0.29 0.07 0.03
14 INT217648 Binding of fa and Hmgcr 1 0.00 0.89 0.03
15 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
16 INT270462 Shh Positive_regulation of Ccnd1 1 0.10 0.6 0.03
17 INT290437 Gene_expression of Mef2c Negative_regulation of Upf1 1 0.02 0.25 0.03
18 INT213559 Binding of Egf and Shh 1 0.17 0.07 0.03
19 INT269943 Sox17 Regulation of Binding of Smad3 1 0.37 0.12 0
20 INT290910 Pkm2 Negative_regulation of Shh 1 0.07 0.06 0
21 INT269915 Binding of Smad2 and Sox17 1 0.21 0.07 0
22 INT205963 GLI1 Positive_regulation of Negative_regulation of SHH 1 0.22 0.58 0
23 INT314850 Shh Regulation of Atoh7 1 0.45 0.22 0
24 INT290908 Regulation of Shh Positive_regulation of Ntn1 1 0.12 0 0
25 INT316355 Binding of CR1 and Hmgcr 1 0.01 0.59 0
26 INT269919 Sox17 Negative_regulation of Binding of Smad3 1 0.36 0 0
27 INT290911 Gene_expression of Shh Positive_regulation of Pkm2 1 0.07 0 0
28 INT290904 Shh Positive_regulation of Prkcg 1 0.26 0.06 0
29 INT282288 Binding of Hmgcr and Nos2 1 0.03 1.99 0
30 INT290900 Prkcg Regulation of Shh 1 0.23 0 0
31 INT269948 Sox17 Positive_regulation of Gene_expression of Ccnd1 1 0.61 0.19 0
32 INT269940 Binding of Sox17 and Scn4a 1 0.17 0.15 0
33 INT350706 Binding of Mef2c and Mir223 1 0.02 0.11 0
34 INT290439 Negative_regulation of Mef2c Positive_regulation of Gene_expression of Ppargc1a 1 0.21 0 0
35 INT205960 Binding of PTCH1 and SHH 1 0.21 0.71 0
36 INT290441 Mef2c Regulation of Mef2b 1 0.09 0.11 0
37 INT290944 Shh Positive_regulation of VEGFA 1 0.04 0.05 0
38 INT269955 Positive_regulation of Binding of Smad3 and Sox17 1 0.39 0.05 0
39 INT269928 Binding of Sox17 and Mgst1 1 0.12 0 0
40 INT270461 Shh Regulation of Gene_expression of Ptch1 1 0.48 0.07 0
41 INT297213 Myoz1 Regulation of Mef2c 1 0.02 0.09 0
42 INT269949 Sox17 Positive_regulation of Ccnd1 1 0.61 0.96 0
43 INT269954 Sox17 Regulation of Gene_expression of Foxa2 1 0.43 0 0
44 INT290438 Mef2c Regulation of Mef2a 1 0.26 0.11 0
45 INT269950 Sox17 Negative_regulation of Gene_expression of Cdkn2b 1 0.27 0.24 0
46 INT205959 Binding of SHH and SMOX 1 0.12 0.72 0
47 INT269947 Sox17 Positive_regulation of Gene_expression of Atxn1 1 0.08 0 0
48 INT269957 Sox17 Negative_regulation of Gene_expression of TGFB1 1 0.04 0 0
49 INT269941 Sox17 Regulation of Gene_expression of Foxa1 1 0.56 0 0
50 INT269942 Sox17 Regulation of Smad3 1 0.37 0.12 0
51 INT270471 Shh Regulation of VEGFA 1 0.39 0.08 0
52 INT269934 Sox17 Regulation of Gopc 1 0.12 0 0
53 INT290898 Shh Positive_regulation of Nos2 1 0.46 0.05 0
54 INT269951 Binding of Sox17 and Gopc 1 0.11 0 0
55 INT269930 Binding of Smad3 and Sox17 1 0.40 1.16 0
56 INT269945 Sox17 Positive_regulation of Localization of Ccnd1 1 0.39 0 0
57 INT270466 Ptch1 Regulation of Gene_expression of Shh 1 0.48 0.07 0
58 INT236171 Binding of LIF and Hmgcr 1 0.02 0 0
59 INT270460 Shh Positive_regulation of Gene_expression of Angpt1 1 0.04 0.08 0
60 INT269922 Sox17 Regulation of Ccnd1 1 0.47 0 0
61 INT269931 Binding of Ccnd1 and Sox17 1 0.33 0.19 0
62 INT270470 Shh Regulation of Gene_expression of VEGFA 1 0.39 0.15 0
63 INT282287 Binding of Cpox and Hmgcr 1 0.01 0.99 0
64 INT269918 Binding of Scn5a and Sox17 1 0.18 0.15 0
65 INT290907 Shh Positive_regulation of Ntn1 1 0.32 0.05 0
66 INT205977 Binding of SHH and Ptch1 1 0.31 0.71 0
67 INT269916 Sox17 Positive_regulation of Pcna 1 0.16 0 0
68 INT270469 Shh Positive_regulation of VEGFA 1 0.29 0.12 0
69 INT329221 Prkag1 Negative_regulation of Hmgcr 1 0.06 0.48 0
70 INT277611 Binding of Mef2c and Hdac4 1 0.34 1.12 0
71 INT270468 Shh Positive_regulation of Gene_expression of VEGFA 1 0.44 0.08 0
72 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0
73 INT295499 Lcat Regulation of Transcription of Hmgcr 1 0.04 0.2 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of skeletal muscle tissue development. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of skeletal muscle tissue development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT182750 Gene_expression of Hmgcr 61 0.58 17.23 7.4
2 INT70801 Gene_expression of Hmgcr 12 0.42 3.08 4.1
3 INT36142 Negative_regulation of Hmgcr 33 0.46 15.91 3.54
4 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
5 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
6 INT113777 Binding of Hmgcr 3 0.09 2.29 1.35
7 INT116903 Negative_regulation of Hmgcr 32 0.43 10.71 1.3
8 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
9 INT236163 Localization of Hmgcr 6 0.64 0.66 1.12
10 INT98975 Positive_regulation of Hmgcr 7 0.16 3.4 1.06
11 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
12 INT277586 Negative_regulation of Mef2c 36 0.59 11.03 0.86
13 INT202361 Gene_expression of Mef2c 28 0.78 5.53 0.67
14 INT203688 Positive_regulation of Hmgcr 10 0.17 6.08 0.52
15 INT206484 Localization of Shh 2 0.75 1.14 0.46
16 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
17 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
18 INT238560 Regulation of Mef2c 9 0.45 2.12 0.33
19 INT232236 Negative_regulation of Gene_expression of Hmgcr 3 0.35 1.36 0.31
20 INT322907 Positive_regulation of Gene_expression of Hmgcr 4 0.03 1.45 0.28
21 INT232795 Positive_regulation of Shh 2 0.70 3.68 0.26
22 INT250545 Regulation of Hmgcr 5 0.11 4.94 0.23
23 INT182749 Binding of Hmgcr 3 0.32 0.55 0.22
24 INT183062 Gene_expression of SHH 12 0.65 5.28 0.21
25 INT202355 Transcription of Mef2c 3 0.69 0.6 0.21
26 INT134477 Negative_regulation of SHH 2 0.37 1.13 0.2
27 INT248543 Positive_regulation of Mef2c 7 0.69 2.82 0.18
28 INT277602 Binding of Mef2c 10 0.39 4.35 0.16
29 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16
30 INT253177 Negative_regulation of Gene_expression of Shh 2 0.55 0.63 0.16
31 INT87196 Regulation of Hmgcr 3 0.45 0.7 0.14
32 INT253190 Localization of Shh 2 0.77 1.06 0.13
33 INT253183 Negative_regulation of Shh 8 0.55 2.13 0.12
34 INT142342 Regulation of Negative_regulation of Hmgcr 1 0.20 0.48 0.1
35 INT270442 Transcription of Shh 1 0.53 0.25 0.09
36 INT213515 Binding of Shh 8 0.37 1.92 0.08
37 INT228554 Negative_regulation of Negative_regulation of Hmgcr 1 0.24 0.44 0.08
38 INT270453 Regulation of Shh 1 0.27 0.83 0.08
39 INT290404 Positive_regulation of Negative_regulation of Mef2c 1 0.50 0.72 0.08
40 INT205973 Binding of SHH 3 0.35 1.03 0.07
41 INT277578 Regulation of Negative_regulation of Mef2c 2 0.45 1.17 0.07
42 INT256862 Regulation of Shh 1 0.25 0 0.07
43 INT290417 Positive_regulation of Gene_expression of Mef2c 1 0.50 1.25 0.06
44 INT153688 Negative_regulation of Negative_regulation of Hmgcr 1 0.42 1.21 0.06
45 INT153690 Localization of Hmgcr 1 0.74 1.21 0.06
46 INT153689 Negative_regulation of Localization of Hmgcr 1 0.42 1.21 0.06
47 INT270445 Positive_regulation of Localization of Shh 1 0.44 0.13 0.05
48 INT181793 Positive_regulation of SHH 3 0.67 2.59 0.04
49 INT208560 Negative_regulation of Shh 2 0.59 2.22 0.04
50 INT290407 Positive_regulation of Binding of Mef2c 1 0.44 0.93 0.04
51 INT282271 Positive_regulation of Regulation of Hmgcr 1 0.12 1.44 0.04
52 INT295501 Negative_regulation of Gene_expression of Hmgcr 1 0.26 0.21 0.04
53 INT311758 Regulation of Gene_expression of Hmgcr 1 0.08 0 0.04
54 INT253187 Negative_regulation of Transcription of Shh 1 0.41 0.55 0.03
55 INT290419 Regulation of Gene_expression of Mef2c 1 0.62 0.41 0.03
56 INT253181 Transcription of Shh 1 0.68 0.54 0.03
57 INT290399 Negative_regulation of Gene_expression of Mef2c 1 0.59 0.59 0.03
58 INT176185 Transcription of Hmgcr 2 0.31 0.56 0
59 INT200864 Positive_regulation of Sox17 2 0.50 0.07 0
60 INT269903 Localization of Sox17 1 0.75 0.07 0
61 INT269907 Positive_regulation of Localization of Sox17 1 0.50 0.2 0
62 INT290400 Regulation of Regulation of Mef2c 1 0.45 0.24 0
63 INT269904 Regulation of Sox17 1 0.45 0 0
64 INT269876 Binding of Sox17 1 0.48 0.72 0
65 INT290429 Negative_regulation of Negative_regulation of Mef2c 1 0.37 0.05 0
66 INT290425 Negative_regulation of Binding of Mef2c 1 0.37 0 0
67 INT269885 Negative_regulation of Sox17 1 0.42 0.32 0
68 INT290918 Negative_regulation of Positive_regulation of Shh 1 0.41 0.25 0
69 INT269891 Positive_regulation of Gene_expression of Sox17 1 0.69 0.4 0
70 INT247129 Positive_regulation of Protein_catabolism of Hmgcr 1 0.06 0.38 0
71 INT290409 Negative_regulation of Transcription of Mef2c 1 0.43 0.08 0
72 INT269878 Negative_regulation of Gene_expression of Sox17 1 0.42 0 0
73 INT176209 Negative_regulation of Transcription of Hmgcr 1 0.25 0.3 0
74 INT269892 Transcription of Sox17 1 0.71 0 0
75 INT173493 Regulation of Gene_expression of Hmgcr 1 0.33 0 0
76 INT247134 Protein_catabolism of Hmgcr 1 0.14 0.38 0
77 INT230972 Positive_regulation of Gene_expression of SHH 1 0.18 0.07 0
78 INT203686 Negative_regulation of Positive_regulation of Hmgcr 1 0.02 0.4 0
79 INT290929 Binding of Shh 1 0.31 0.1 0
80 INT269898 Positive_regulation of Binding of Sox17 1 0.44 0 0
81 INT290927 Regulation of Positive_regulation of Shh 1 0.23 0 0
82 INT269869 Gene_expression of Sox17 1 0.77 2.48 0
83 INT269882 Regulation of Gene_expression of Sox17 1 0.61 0.14 0
84 INT277587 Localization of Mef2c 1 0.65 0.43 0
85 INT295506 Transcription of Hmgcr 1 0.43 0.19 0
86 INT270449 Negative_regulation of Positive_regulation of Shh 1 0.43 0.24 0
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