GO:0048645

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Name organ formation
Categary Process
Go Slim No
Go Link GO:0048645
Unique Molecular Interactions 162
Total Molecular Interactions 220
Total Single Events 1604
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for organ formation. They are ordered first by their pain relevance and then by number of times they were reported for organ formation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT101259 Gata6 Negative_regulation of Gene_expression of ALOX15 1 0.42 0.67 0.89
2 INT101258 Gene_expression of Gata6 Negative_regulation of Positive_regulation of ALOX15 1 0.42 0.65 0.87
3 INT137699 AR Regulation of PDYN 1 0.46 0.93 0.75
4 INT185917 Binding of AR and MAPK1 1 0.07 0.5 0.47
5 INT252425 Positive_regulation of AR Positive_regulation of Gene_expression of CXCL10 1 0.00 0.9 0.44
6 INT139047 Negative_regulation of AR Negative_regulation of Positive_regulation of CPOX 1 0.07 0.76 0.4
7 INT252453 Binding of AR and Adora2b 1 0.05 0 0.35
8 INT75641 AR Positive_regulation of Positive_regulation of EIF2B3 1 0.02 0 0.33
9 INT349664 PYCARD Negative_regulation of Localization of AR 1 0.05 0 0.32
10 INT280926 Hoxa3 Positive_regulation of Gene_expression of Ccl2 1 0.53 2.61 0.32
11 INT349662 Binding of PYCARD and Negative_regulation of Localization of AR 1 0.05 0 0.32
12 INT223042 AR Positive_regulation of ADCY1 1 0.01 0.41 0.25
13 INT257776 Phosphorylation of AR Positive_regulation of Localization of TAB2 1 0.26 0.38 0.24
14 INT252427 IGKV2D-29 Regulation of Gene_expression of AR 1 0.02 0 0.24
15 INT139046 Negative_regulation of AR Negative_regulation of Phosphorylation of DYT10 1 0.33 0.34 0.23
16 INT139050 Negative_regulation of AR Negative_regulation of Phosphorylation of PRKCB 1 0.02 0.34 0.23
17 INT139045 Negative_regulation of AR Negative_regulation of CPOX 1 0.07 0.34 0.23
18 INT139048 Negative_regulation of AR Negative_regulation of Positive_regulation of TRAF3IP2 1 0.02 0.34 0.23
19 INT139049 Negative_regulation of AR Negative_regulation of Positive_regulation of DYT10 1 0.33 0.34 0.23
20 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
21 INT198382 Binding of AR and SRD5A1 2 0.06 0.84 0.17
22 INT122361 Binding of AR and OPRM1 1 0.26 0.14 0.16
23 INT122362 AR Positive_regulation of Positive_regulation of OPRM1 1 0.32 0.19 0.14
24 INT209645 AR Regulation of STUB1 1 0.04 0.93 0.13
25 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13
26 INT169128 Trove2 Negative_regulation of Gene_expression of AR 1 0.05 0.94 0.13
27 INT223040 AR Positive_regulation of Negative_regulation of TFPI 1 0.03 0 0.13
28 INT354620 AR Positive_regulation of Hspg2 1 0.00 0 0.12
29 INT251114 Binding of AR and Ctnnb1 1 0.01 1 0.12
30 INT185918 AR Positive_regulation of Gene_expression of NOS2 1 0.12 0.21 0.11
31 INT220743 Binding of AR and EGFR 1 0.01 0.46 0.1
32 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
33 INT178434 Il6 Positive_regulation of Ar 1 0.01 0.93 0.08
34 INT257777 INCENP Positive_regulation of AR 1 0.04 0.49 0.08
35 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
36 INT213933 AR Negative_regulation of Cyp19a1 1 0.07 0.79 0.07
37 INT224293 AR Positive_regulation of Protein_catabolism of ESR1 1 0.24 0.4 0.07
38 INT328380 AR Negative_regulation of Gene_expression of Ghrl 1 0.01 0.55 0.07
39 INT298349 HES3 Positive_regulation of Shh 1 0.12 0.14 0.07
40 INT293813 ERBB2 Positive_regulation of Positive_regulation of AR 1 0.09 0.45 0.07
41 INT303562 Binding of Fgf10 and Fgfr2 1 0.40 0.88 0.07
42 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
43 INT201866 Binding of AR and PGR 1 0.07 0.34 0.06
44 INT339110 ERBB2 Positive_regulation of GATA6 1 0.31 0.67 0.06
45 INT338019 Egf Positive_regulation of AR 1 0.07 1.02 0.05
46 INT349665 Positive_regulation of Binding of AR and TFPI 1 0.02 0 0.05
47 INT349667 Binding of AR and TFPI 1 0.02 0 0.05
48 INT209644 Binding of AR and C4B 1 0.00 0.32 0.04
49 INT178441 Binding of Ar and Sra1 1 0.00 0.45 0.04
50 INT213383 Srd5a3 Negative_regulation of Gene_expression of AR 1 0.01 0.7 0.04
51 INT319384 Binding of AR and SCGB2A2 1 0.01 1.36 0.04
52 INT213563 Binding of Ctnnd2 and Shh 1 0.27 0.09 0.04
53 INT270459 Binding of Shh and Gli1 1 0.02 0.65 0.04
54 INT178439 Binding of Ar and Src 1 0.01 0.44 0.04
55 INT178428 Regulation of Il6 Positive_regulation of Ar 1 0.01 0.47 0.04
56 INT352014 Shh Positive_regulation of Gene_expression of Pax1 1 0.29 0.07 0.03
57 INT279632 Positive_regulation of Binding of Ar and Nr4a1 1 0.01 0.86 0.03
58 INT326736 AR Regulation of Gene_expression of ARG2 1 0.34 0.43 0.03
59 INT185651 GOPC Positive_regulation of AR 1 0.03 0.06 0.03
60 INT349661 PYCARD Positive_regulation of AR 1 0.08 0 0.03
61 INT198143 Binding of AR and ANTXR2 1 0.01 0.19 0.03
62 INT303563 Binding of Fgf10 and Dysf 1 0.00 0.44 0.03
63 INT326742 AR Regulation of Gene_expression of ARG1 1 0.24 0.43 0.03
64 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
65 INT270462 Shh Positive_regulation of Ccnd1 1 0.10 0.6 0.03
66 INT279634 Binding of Ar and Nr4a1 1 0.01 0.85 0.03
67 INT213559 Binding of Egf and Shh 1 0.17 0.07 0.03
68 INT218964 Dlst Regulation of AR 1 0.01 0 0.03
69 INT265730 Binding of AR and VEGFA 1 0.09 0 0
70 INT338180 Binding of AR and STAT3 1 0.18 0.3 0
71 INT304020 AR Regulation of TP53 1 0.24 1.11 0
72 INT339404 Binding of Ar and Tymp 1 0.10 0.06 0
73 INT290910 Pkm2 Negative_regulation of Shh 1 0.07 0.06 0
74 INT218963 Dlst Negative_regulation of AR 1 0.00 0.1 0
75 INT209636 TRPV1 Regulation of Gene_expression of AR 1 0.17 0.38 0
76 INT339403 Negative_regulation of Binding of Ar and Tymp 1 0.12 0 0
77 INT250132 Binding of Hoxa3 and Gopc 1 0.07 0 0
78 INT293809 MAPK1 Positive_regulation of AR 1 0.03 0.12 0
79 INT209633 AR Regulation of Gene_expression of PCa 1 0.06 1.19 0
80 INT205963 GLI1 Positive_regulation of Negative_regulation of SHH 1 0.22 0.58 0
81 INT314850 Shh Regulation of Atoh7 1 0.45 0.22 0
82 INT269944 Gata6 Regulation of Gene_expression of Foxj1 1 0.19 0 0
83 INT213365 AR Regulation of Gene_expression of VEGFA 1 0.09 1.52 0
84 INT290908 Regulation of Shh Positive_regulation of Ntn1 1 0.12 0 0
85 INT338018 Binding of AR and Flna 1 0.11 0.33 0
86 INT209634 Binding of AR and PCa 1 0.04 1.03 0
87 INT293818 AKT1 Positive_regulation of Gene_expression of AR 1 0.05 0.31 0
88 INT349666 Binding of AR and PYCARD 1 0.06 0 0
89 INT290911 Gene_expression of Shh Positive_regulation of Pkm2 1 0.07 0 0
90 INT326740 Gene_expression of AR Negative_regulation of Gene_expression of ARG2 1 0.24 0.8 0
91 INT290904 Shh Positive_regulation of Prkcg 1 0.26 0.06 0
92 INT290900 Prkcg Regulation of Shh 1 0.23 0 0
93 INT209630 ALG12 Regulation of Gene_expression of AR 1 0.13 0.38 0
94 INT209635 AR Positive_regulation of ALG12 1 0.14 0.32 0
95 INT338194 Regulation of VAV3 Regulation of AR 1 0.31 0.49 0
96 INT293803 Negative_regulation of ERBB2 Negative_regulation of Gene_expression of AR 1 0.10 0 0
97 INT205960 Binding of PTCH1 and SHH 1 0.21 0.71 0
98 INT233279 Binding of TLX1 and Tgif1 1 0.00 0.05 0
99 INT293819 EPHB2 Positive_regulation of AR 1 0.23 0.12 0
100 INT290944 Shh Positive_regulation of VEGFA 1 0.04 0.05 0
101 INT270461 Shh Regulation of Gene_expression of Ptch1 1 0.48 0.07 0
102 INT338197 CCND1 Negative_regulation of AR 1 0.24 0 0
103 INT354619 AR Positive_regulation of Gene_expression of Nppa 1 0.00 0.38 0
104 INT338022 Cuedc2 Positive_regulation of Protein_catabolism of AR 1 0.23 0.29 0
105 INT218960 Binding of AR and Esyt1 1 0.00 0 0
106 INT209637 AR Positive_regulation of TRPV1 1 0.18 0.32 0
107 INT217780 MIR181A1 Regulation of GATA6 1 0.17 0.7 0
108 INT293806 AR Positive_regulation of PIK3CG 1 0.06 0.12 0
109 INT205959 Binding of SHH and SMOX 1 0.12 0.72 0
110 INT209629 AR Negative_regulation of Gene_expression of MRFAP1 1 0.26 0.16 0
111 INT185652 Binding of AR and GOPC 1 0.03 0 0
112 INT338182 CDCP1 Positive_regulation of Phosphorylation of AR 1 0.01 0.29 0
113 INT339407 Negative_regulation of Binding of AR and Tymp 1 0.04 0 0
114 INT102124 Binding of AR and ESRRB 1 0.03 0.13 0
115 INT218965 Esyt1 Negative_regulation of AR 1 0.00 0 0
116 INT270471 Shh Regulation of VEGFA 1 0.39 0.08 0
117 INT209641 AR Positive_regulation of PCa 1 0.06 1.17 0
118 INT290898 Shh Positive_regulation of Nos2 1 0.46 0.05 0
119 INT338021 Binding of Flna and Regulation of Transcription of AR 1 0.14 0.33 0
120 INT265737 Binding of AR and NRP1 1 0.10 0 0
121 INT202675 Fgf10 Positive_regulation of Fgfr2 1 0.45 0.07 0
122 INT326743 Gene_expression of AR Negative_regulation of Gene_expression of ARG1 1 0.32 0.8 0
123 INT209638 AR Regulation of MRFAP1 1 0.12 0.41 0
124 INT270466 Ptch1 Regulation of Gene_expression of Shh 1 0.48 0.07 0
125 INT339406 Binding of AR and Tymp 1 0.03 0.06 0
126 INT338023 Psma7 Positive_regulation of AR 1 0.17 0.38 0
127 INT279635 Ar Regulation of Abpe 1 0.01 1.55 0
128 INT270460 Shh Positive_regulation of Gene_expression of Angpt1 1 0.04 0.08 0
129 INT265756 Positive_regulation of Binding of AR and NRP1 1 0.10 0 0
130 INT293816 Binding of AR and PIK3CG 1 0.03 0.27 0
131 INT198110 Ar Positive_regulation of Gene_expression of Aqp9 1 0.13 0 0
132 INT218962 Dlst Regulation of Gene_expression of AR 1 0.01 0 0
133 INT270470 Shh Regulation of Gene_expression of VEGFA 1 0.39 0.15 0
134 INT185654 DBT Negative_regulation of AR 1 0.02 0.09 0
135 INT290907 Shh Positive_regulation of Ntn1 1 0.32 0.05 0
136 INT205977 Binding of SHH and Ptch1 1 0.31 0.71 0
137 INT338020 Binding of AR and Ddr1 1 0.03 0.45 0
138 INT279633 Binding of Ar and Abpe 1 0.01 0.99 0
139 INT293810 Binding of AR and RORC 1 0.01 0.13 0
140 INT270469 Shh Positive_regulation of VEGFA 1 0.29 0.12 0
141 INT338185 VAV3 Regulation of Positive_regulation of AR 1 0.19 0.49 0
142 INT338193 VAV3 Regulation of AR 1 0.31 0.49 0
143 INT209643 AR Positive_regulation of PYCR1 1 0.31 1.17 0
144 INT270468 Shh Positive_regulation of Gene_expression of VEGFA 1 0.44 0.08 0
145 INT213364 AR Regulation of VEGFA 1 0.09 0.68 0
146 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0
147 INT117173 OCM Regulation of Transcription of AR 1 0.18 0.06 0
148 INT269956 Gata6 Regulation of Gene_expression of Scgb1a1 1 0.17 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for organ formation. They are ordered first by their pain relevance and then by number of times they were reported in organ formation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5206 Gene_expression of AR 316 0.78 113.83 27.29
2 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66
3 INT35366 Binding of AR 87 0.47 30.52 8.9
4 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61
5 INT99091 Regulation of AR 70 0.45 31.68 5.05
6 INT5205 Localization of AR 43 0.80 12.87 4.63
7 INT84727 Negative_regulation of Gene_expression of AR 38 0.58 12.46 4.63
8 INT5204 Positive_regulation of Gene_expression of AR 60 0.67 23.54 3.53
9 INT101246 Gene_expression of Gata6 6 0.68 3.03 2.68
10 INT185927 Positive_regulation of Positive_regulation of AR 12 0.34 6.35 2.5
11 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
12 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
13 INT101252 Negative_regulation of Gene_expression of Gata6 1 0.51 1.3 1.74
14 INT101244 Regulation of Gata6 3 0.40 1.52 1.7
15 INT84722 Regulation of Gene_expression of AR 20 0.61 7.73 1.69
16 INT10598 Gene_expression of Ar 10 0.64 3.44 1.61
17 INT15969 Negative_regulation of Ar 11 0.43 2.77 1.59
18 INT250114 Gene_expression of Hoxa3 36 0.77 23.04 1.46
19 INT82932 Transcription of AR 14 0.67 5.75 1.34
20 INT68500 Regulation of Ar 6 0.27 4.16 1.32
21 INT213379 Phosphorylation of AR 6 0.63 2.03 1.21
22 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
23 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
24 INT209679 Positive_regulation of Regulation of AR 3 0.37 1.88 0.96
25 INT101248 Negative_regulation of Gata6 1 0.37 0.83 0.85
26 INT101251 Negative_regulation of Positive_regulation of Gata6 1 0.38 0.83 0.85
27 INT101250 Positive_regulation of Gata6 1 0.41 0.83 0.84
28 INT101245 Transcription of Gata6 2 0.47 0.85 0.82
29 INT156529 Positive_regulation of Gene_expression of Ar 1 0.05 0.09 0.8
30 INT185669 Positive_regulation of Localization of AR 7 0.33 1.83 0.73
31 INT156060 Regulation of Binding of AR 2 0.09 0.42 0.69
32 INT17493 Binding of Ar 14 0.48 3.62 0.6
33 INT49343 Positive_regulation of Ar 8 0.42 4.38 0.58
34 INT296583 Gene_expression of Fgf10 3 0.59 2.64 0.57
35 INT296594 Regulation of Fgf10 1 0.15 1.53 0.56
36 INT206484 Localization of Shh 2 0.75 1.14 0.46
37 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
38 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
39 INT104312 Positive_regulation of Transcription of AR 2 0.37 0.96 0.38
40 INT17492 Negative_regulation of Binding of Ar 3 0.59 0.76 0.28
41 INT293387 Regulation of Localization of AR 1 0.05 0 0.28
42 INT266974 Protein_catabolism of AR 2 0.34 1.91 0.27
43 INT250126 Localization of Hoxa3 4 0.74 1.5 0.26
44 INT232795 Positive_regulation of Shh 2 0.70 3.68 0.26
45 INT123520 Gene_expression of Ar 12 0.32 6.98 0.25
46 INT279628 Negative_regulation of Ar 5 0.04 6.1 0.25
47 INT185930 Regulation of Positive_regulation of AR 3 0.20 1.01 0.25
48 INT152667 Negative_regulation of Transcription of AR 3 0.42 0.72 0.24
49 INT112378 Negative_regulation of Regulation of Ar 1 0.43 0.19 0.23
50 INT183062 Gene_expression of SHH 12 0.65 5.28 0.21
51 INT257784 Positive_regulation of Phosphorylation of AR 2 0.45 0.96 0.21
52 INT134477 Negative_regulation of SHH 2 0.37 1.13 0.2
53 INT250111 Negative_regulation of Gene_expression of Hoxa3 2 0.43 1.3 0.19
54 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16
55 INT253177 Negative_regulation of Gene_expression of Shh 2 0.55 0.63 0.16
56 INT49346 Transcription of Ar 3 0.63 0.8 0.14
57 INT123527 Negative_regulation of Gene_expression of Ar 2 0.10 0 0.14
58 INT253190 Localization of Shh 2 0.77 1.06 0.13
59 INT152669 Negative_regulation of Localization of AR 2 0.25 0.75 0.13
60 INT253183 Negative_regulation of Shh 8 0.55 2.13 0.12
61 INT185673 Negative_regulation of Negative_regulation of AR 3 0.28 1.12 0.12
62 INT243079 Regulation of Ar 3 0.08 1.22 0.12
63 INT280917 Regulation of Gene_expression of Hoxa3 1 0.45 2.12 0.12
64 INT162432 Positive_regulation of Ar 3 0.23 2.34 0.11
65 INT270442 Transcription of Shh 1 0.53 0.25 0.09
66 INT213515 Binding of Shh 8 0.37 1.92 0.08
67 INT270453 Regulation of Shh 1 0.27 0.83 0.08
68 INT162428 Localization of Ar 4 0.37 2.4 0.07
69 INT205973 Binding of SHH 3 0.35 1.03 0.07
70 INT256862 Regulation of Shh 1 0.25 0 0.07
71 INT162430 Negative_regulation of Positive_regulation of Ar 1 0.21 1.52 0.07
72 INT243082 Binding of Ar 2 0.11 1.81 0.06
73 INT339183 Positive_regulation of GATA6 1 0.16 0.66 0.06
74 INT270445 Positive_regulation of Localization of Shh 1 0.44 0.13 0.05
75 INT181793 Positive_regulation of SHH 3 0.67 2.59 0.04
76 INT185666 Positive_regulation of Binding of AR 2 0.33 0.19 0.04
77 INT250125 Positive_regulation of Hoxa3 2 0.50 0.74 0.04
78 INT208560 Negative_regulation of Shh 2 0.59 2.22 0.04
79 INT213380 Regulation of Negative_regulation of AR 1 0.35 0.72 0.04
80 INT260760 Positive_regulation of Fgf10 2 0.53 0.43 0.03
81 INT213363 Regulation of Gene_expression of Ar 2 0.11 1.63 0.03
82 INT303535 Positive_regulation of Gene_expression of Fgf10 1 0.53 0.34 0.03
83 INT276355 Gene_expression of TLX1 1 0.17 3.95 0.03
84 INT253187 Negative_regulation of Transcription of Shh 1 0.41 0.55 0.03
85 INT253181 Transcription of Shh 1 0.68 0.54 0.03
86 INT123526 Positive_regulation of Gene_expression of Ar 2 0.11 1.29 0
87 INT209673 Negative_regulation of Binding of AR 2 0.27 0.5 0
88 INT182748 Positive_regulation of Transcription of Ar 1 0.46 0.43 0
89 INT217818 Gene_expression of GATA6 1 0.17 1.07 0
90 INT250120 Negative_regulation of Hoxa3 1 0.40 0.09 0
91 INT287660 Negative_regulation of Negative_regulation of Ar 1 0.03 0.07 0
92 INT276353 Positive_regulation of Gene_expression of TLX1 1 0.10 1.39 0
93 INT185672 Positive_regulation of Negative_regulation of AR 1 0.27 0 0
94 INT335677 Regulation of Localization of Ar 1 0.00 0 0
95 INT146803 Negative_regulation of Gene_expression of Ar 1 0.16 0.08 0
96 INT293401 Regulation of Gene_expression of Ar 1 0.06 0.07 0
97 INT152665 Negative_regulation of Regulation of AR 1 0.25 0.38 0
98 INT290918 Negative_regulation of Positive_regulation of Shh 1 0.41 0.25 0
99 INT276367 Regulation of Gene_expression of TLX1 1 0.10 1.4 0
100 INT230972 Positive_regulation of Gene_expression of SHH 1 0.18 0.07 0
101 INT290929 Binding of Shh 1 0.31 0.1 0
102 INT328768 Positive_regulation of Gene_expression of Gata6 1 0.19 0.61 0
103 INT152664 Regulation of Transcription of AR 1 0.16 0.25 0
104 INT293772 Negative_regulation of Positive_regulation of AR 1 0.19 0 0
105 INT290927 Regulation of Positive_regulation of Shh 1 0.23 0 0
106 INT123516 Phosphorylation of Ar 1 0.19 0.07 0
107 INT339154 Negative_regulation of GATA6 1 0.14 0.86 0
108 INT270449 Negative_regulation of Positive_regulation of Shh 1 0.43 0.24 0
109 INT250127 Regulation of Localization of Hoxa3 1 0.43 0.1 0
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