GO:0048662

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Name negative regulation of smooth muscle cell proliferation
Categary Process
Go Slim No
Go Link GO:0048662
Unique Molecular Interactions 1144
Total Molecular Interactions 1512
Total Single Events 13904
Pain Genes Associated 51

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of smooth muscle cell proliferation. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of smooth muscle cell proliferation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
2 INT24742 Binding of Calca and Vip 1 0.37 0.18 4.68
3 INT7022 Drd1a Positive_regulation of Npr1 6 0.05 0.26 4.32
4 INT3434 Vip Positive_regulation of Localization of Prl 6 0.76 0.16 3.21
5 INT69030 IL18 Positive_regulation of IL12A 3 0.31 5.57 2.72
6 INT111787 Cck Regulation of Gene_expression of Npr1 1 0.22 1.68 2.57
7 INT350148 Binding of IL12A and ERAL1 1 0.21 8.23 2.26
8 INT240131 Binding of Crp and Nppb 7 0.07 11.53 2.12
9 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
10 INT33756 Akr1d1 Positive_regulation of Npr1 3 0.01 0 2.05
11 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
12 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
13 INT21261 Penk Negative_regulation of Npr1 1 0.02 0 2
14 INT7023 Negative_regulation of Drd1a Positive_regulation of Npr1 2 0.05 0.1 1.81
15 INT185143 Elane Positive_regulation of Pik3r1 1 0.01 0 1.72
16 INT68709 Positive_regulation of Crh Regulation of Npr1 1 0.03 0 1.71
17 INT68710 Crh Regulation of Npr1 1 0.03 0 1.7
18 INT96296 Oprm1 Negative_regulation of Npr1 2 0.05 0.32 1.65
19 INT278223 Binding of NOS3 and ACSM3 1 0.41 6.32 1.65
20 INT33757 Hmmr Positive_regulation of Npr1 1 0.01 0 1.59
21 INT306745 Binding of Il12a and IL23A 1 0.10 3.25 1.56
22 INT54844 Negative_regulation of Penk Positive_regulation of Vip 1 0.26 0 1.54
23 INT69031 IL12A Positive_regulation of IFNA1 9 0.13 4.23 1.52
24 INT42001 Cck Regulation of Vip 1 0.28 0 1.51
25 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
26 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
27 INT92057 Ifng Positive_regulation of Gene_expression of Ik 1 0.03 0.45 1.49
28 INT41999 Trpv1 Positive_regulation of Vip 1 0.04 0 1.49
29 INT112034 Gabrb3 Positive_regulation of Pik3r1 1 0.08 0.18 1.48
30 INT172203 Binding of Comt and Maoa 1 0.31 0.98 1.43
31 INT128913 Binding of COMT and PENK 1 0.30 0.07 1.41
32 INT83626 Ifng Positive_regulation of Gene_expression of Cd59 1 0.33 2.19 1.41
33 INT134764 Ghrl Regulation of Gene_expression of NOS3 1 0.02 2.66 1.4
34 INT51213 Vip Regulation of Localization of Calca 1 0.38 0 1.39
35 INT128914 COMT Regulation of OPRM1 1 0.39 0.07 1.39
36 INT108583 Binding of Vip and Fos 1 0.36 0 1.39
37 INT6466 Binding of Npr1 and Oprd1 1 0.01 0 1.37
38 INT160587 IFNG Positive_regulation of Gene_expression of OPRM1 1 0.18 0.54 1.35
39 INT262377 Binding of Comt and Fmod 1 0.06 1.47 1.29
40 INT34052 POMC Regulation of Gene_expression of IFNG 1 0.11 0 1.27
41 INT8409 IL1A Positive_regulation of Positive_regulation of Vip 1 0.01 0.63 1.27
42 INT87026 ZAK Positive_regulation of Gene_expression of IL12A 3 0.12 2.55 1.26
43 INT143620 Ltp Positive_regulation of Npr1 1 0.01 0.16 1.26
44 INT42554 Oprl1 Regulation of Npr1 2 0.06 0 1.22
45 INT56881 Ppbp Regulation of Vip 1 0.00 0 1.22
46 INT70046 IL12A Regulation of IL10 1 0.07 1.42 1.21
47 INT70045 IL12A Regulation of Negative_regulation of PRF1 1 0.04 1.42 1.21
48 INT70044 IL12A Regulation of PRF1 1 0.04 1.42 1.21
49 INT70034 IL12A Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
50 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2
51 INT83428 Binding of ADIPOQ and FRTS 3 0.18 2.02 1.19
52 INT261617 SNRNP70 Regulation of Comt 1 0.01 0.4 1.18
53 INT13205 Oprd1 Negative_regulation of Npr1 2 0.01 0 1.16
54 INT111221 MMEL1 Negative_regulation of HMOX1 1 0.01 1 1.16
55 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
56 INT13204 Binding of Npr1 and Akr1d1 1 0.00 0 1.14
57 INT7024 Regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.07 1.13
58 INT156545 Il13 Positive_regulation of Gene_expression of Il12a 1 0.27 1.56 1.13
59 INT40700 Vip Regulation of Localization of Sst 1 0.02 0 1.11
60 INT122889 Ifng Positive_regulation of Gene_expression of HLA-E 1 0.02 0.97 1.1
61 INT31549 Binding of Dbh and Vip 1 0.32 0 1.08
62 INT31547 Binding of Th and Vip 1 0.31 0 1.08
63 INT8410 IL1A Positive_regulation of Vip 1 0.02 0.68 1.05
64 INT113235 Tacr1 Regulation of Gene_expression of Ifng 1 0.26 1 1.04
65 INT88875 Ifng Positive_regulation of Transcription of Nos2 1 0.02 0.27 1.03
66 INT128700 BBS9 Negative_regulation of Il12a 1 0.47 0.76 1.03
67 INT33142 Pck1 Positive_regulation of Npr1 4 0.01 0.5 1.02
68 INT88874 Ifng Regulation of Nos2 1 0.01 0.26 1.01
69 INT13502 Penk Positive_regulation of Npr1 1 0.02 0.19 1.01
70 INT13503 Regulation of Penk Positive_regulation of Npr1 1 0.02 0.19 1.01
71 INT88879 Ifng Positive_regulation of Nfkb1 1 0.01 0.26 1.01
72 INT7025 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.08 1.01
73 INT139639 Jun Negative_regulation of Positive_regulation of Vip 1 0.53 1.07 1
74 INT317564 Pik3r1 Regulation of Negative_regulation of Oprm1 1 0.13 0.07 1
75 INT42555 Oprl1 Negative_regulation of Npr1 1 0.02 0 0.99
76 INT110033 Adrb1 Positive_regulation of Gene_expression of Il12a 1 0.05 0 0.99
77 INT139641 Positive_regulation of Jun Positive_regulation of Positive_regulation of Vip 1 0.37 0.95 0.99
78 INT94493 Avp Positive_regulation of Gene_expression of Ifng 1 0.05 1.73 0.97
79 INT77142 Binding of IFNG and IL4 2 0.03 1.16 0.95
80 INT265649 TBK1 Negative_regulation of COMT 1 0.01 0.61 0.94
81 INT84091 Negative_regulation of Nka1 Regulation of Vip 1 0.00 0 0.93
82 INT336017 Vip Regulation of Tlr4 1 0.22 1.23 0.93
83 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92
84 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
85 INT84089 Nka1 Regulation of Localization of Vip 1 0.00 0 0.92
86 INT94501 Il2 Positive_regulation of Gene_expression of Ifng 1 0.03 1.63 0.92
87 INT84088 Nka1 Regulation of Vip 1 0.01 0 0.92
88 INT85879 Il12a Positive_regulation of Gene_expression of Ifng 1 0.20 0.89 0.92
89 INT147474 Nfe2l2 Positive_regulation of Hmox1 1 0.43 0.38 0.9
90 INT78449 Abat Positive_regulation of Localization of Vip 1 0.23 0 0.89
91 INT165627 Binding of COMT and SLTM 1 0.09 0.86 0.88
92 INT28194 Nppb Positive_regulation of CYP2B6 1 0.50 0.05 0.88
93 INT28193 Nppb Positive_regulation of Positive_regulation of RYBP 1 0.29 0.05 0.88
94 INT91272 Ifng Positive_regulation of Localization of Il6 1 0.29 0 0.88
95 INT187225 Vip Negative_regulation of Gene_expression of Tnfrsf11a 1 0.27 1.92 0.87
96 INT202254 Binding of COMT and DRD2 1 0.41 0.23 0.86
97 INT133176 Regulation of Mastl Negative_regulation of Il12a 1 0.01 0.24 0.86
98 INT133177 Mastl Negative_regulation of Il12a 1 0.01 0.24 0.86
99 INT111790 Penk Regulation of Gene_expression of Npr1 1 0.22 0.56 0.86
100 INT120999 Binding of Oprm1 and Ifng 1 0.22 0.57 0.84
101 INT41156 Sst Negative_regulation of Npr1 1 0.05 0 0.84
102 INT41868 GRP Regulation of Vip 1 0.01 0 0.84
103 INT29781 PDYN Negative_regulation of Npr1 1 0.00 0.22 0.84
104 INT249656 tm Positive_regulation of Il12a 1 0.07 1.17 0.84
105 INT41858 Nts Regulation of Vip 1 0.10 0 0.84
106 INT41860 Agtr2 Regulation of Vip 1 0.02 0 0.84
107 INT41857 Avp Regulation of Vip 1 0.01 0 0.84
108 INT282506 ocd Positive_regulation of Gene_expression of Comt 1 0.32 1.26 0.84
109 INT41861 Vip Regulation of Cck 1 0.02 0 0.84
110 INT340115 Comt Regulation of Localization of Dusp1 1 0.12 0.83 0.83
111 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
112 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
113 INT102931 Nos3 Positive_regulation of Nos2 1 0.43 1.63 0.83
114 INT340114 Comt Regulation of Localization of Pain1 1 0.02 0.83 0.83
115 INT94331 IFNG Positive_regulation of CXCL10 4 0.11 1.31 0.82
116 INT3432 Vip Positive_regulation of Prl 2 0.45 0 0.82
117 INT19299 ANG Regulation of AVP 1 0.25 0 0.82
118 INT113240 Il12a Regulation of Transcription of Tacr1 1 0.21 0.79 0.82
119 INT340113 Comt Regulation of Bdnf 1 0.21 0.74 0.82
120 INT322266 Binding of LIG4 and NOS3 1 0.02 2.35 0.82
121 INT102932 Nos3 Positive_regulation of NOS1 1 0.03 1.63 0.82
122 INT187226 Vip Positive_regulation of Gene_expression of Il1rn 1 0.04 0.96 0.82
123 INT187232 Vip Positive_regulation of Gene_expression of Il10 1 0.16 0.95 0.81
124 INT262564 Ngf Positive_regulation of Pik3r1 1 0.08 0.36 0.8
125 INT8411 IL2 Regulation of Gene_expression of Vip 1 0.00 0.27 0.8
126 INT113238 Il12a Positive_regulation of Transcription of Tacr1 1 0.38 0.78 0.79
127 INT240619 Binding of CRP and ADIPOQ 8 0.18 10.74 0.78
128 INT298457 Binding of Calca and Npr1 1 0.01 0.39 0.77
129 INT166902 NPPB Positive_regulation of TRPA1 1 0.78 0.76 0.77
130 INT81299 Ifng Positive_regulation of Gene_expression of Hmox1 1 0.52 0.75 0.76
131 INT21260 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.05 0 0.76
132 INT147619 Npr1 Positive_regulation of Localization of Calca 1 0.03 0 0.75
133 INT266100 Binding of COMT and SH2B2 1 0.25 1.22 0.74
134 INT327707 Binding of Comt and Drd1a 1 0.18 0.27 0.74
135 INT266108 Binding of COMT and HPS1 1 0.23 1.21 0.74
136 INT57658 ASNA1 Positive_regulation of Npr1 1 0.00 0.15 0.74
137 INT327702 Binding of Comt and Drd2 1 0.28 0.27 0.74
138 INT327712 Binding of Comt and Rbm39 1 0.00 0.27 0.74
139 INT84090 Nka1 Positive_regulation of Localization of Vip 1 0.00 0 0.74
140 INT213026 Hdl1 Positive_regulation of Nos3 5 0.16 7.92 0.73
141 INT287132 Binding of NT5E and Comt 1 0.03 0.11 0.73
142 INT172134 Binding of IL6 and IL15 2 0.01 1.18 0.72
143 INT172147 Binding of IL15 and TNF 2 0.05 1.19 0.72
144 INT209029 Il12b Positive_regulation of Elf1 1 0.24 0.37 0.72
145 INT209031 Il12b Positive_regulation of Ccr1 1 0.02 0.37 0.72
146 INT209030 Il12b Positive_regulation of Cxcl1 1 0.16 0.37 0.72
147 INT209028 Il12b Positive_regulation of Il17a 1 0.12 0.37 0.72
148 INT209032 Il12b Positive_regulation of Csf2 1 0.08 0.37 0.72
149 INT146460 IFNG Positive_regulation of Gene_expression of TNFRSF10D 1 0.03 1.46 0.72
150 INT151679 Ifng Negative_regulation of Oas1b 1 0.12 1.24 0.71
151 INT317573 Binding of Oprm1 and Pik3r1 1 0.12 0.33 0.71
152 INT146461 IFNG Positive_regulation of NFKB1 1 0.01 1.44 0.71
153 INT151676 Ifng Negative_regulation of Art2a-ps 1 0.00 1.25 0.71
154 INT184125 Il12a Positive_regulation of Stat4 2 0.11 1.04 0.7
155 INT99818 IFNG Positive_regulation of Gene_expression of APP 1 0.04 0.82 0.7
156 INT169603 Nppb Regulation of Npr1 1 0.26 0.95 0.69
157 INT99743 Olr1742 Regulation of Gene_expression of Hmox1 1 0.00 0 0.68
158 INT71988 Drd1a Regulation of Npr1 1 0.10 0 0.68
159 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66
160 INT220032 Nos1 Positive_regulation of Nos3 1 0.32 0.45 0.66
161 INT111555 Negative_regulation of Npr1 Negative_regulation of Positive_regulation of Creb1 1 0.02 0.58 0.66
162 INT86519 Binding of Hmox1 and Hmox2 1 0.08 0.1 0.66
163 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65
164 INT103868 IFNG Positive_regulation of Hmox1 1 0.09 0.83 0.65
165 INT317560 Binding of Pdpk1 and Pik3r1 1 0.13 0 0.65
166 INT309664 Binding of Pik3r1 and Cia1 1 0.02 1.32 0.64
167 INT142076 IL4 Negative_regulation of Gene_expression of IFNG 1 0.01 1.58 0.64
168 INT6464 Sst Regulation of Negative_regulation of Npr1 1 0.01 0 0.64
169 INT99744 Calca Positive_regulation of Positive_regulation of Hmox1 1 0.48 0 0.64
170 INT103870 IRF6 Positive_regulation of Hmox1 1 0.14 0.83 0.64
171 INT6463 Oprd1 Regulation of Negative_regulation of Npr1 1 0.01 0 0.63
172 INT6465 Trh Regulation of Negative_regulation of Npr1 1 0.01 0 0.63
173 INT116752 Ngf Regulation of Pik3r1 1 0.56 0.29 0.63
174 INT255994 Binding of Ang and Il1rn 1 0.09 1.21 0.63
175 INT56235 Ifng Positive_regulation of Gene_expression of RT1-EC2 1 0.23 0.33 0.62
176 INT32782 Binding of Vip and Elane 1 0.17 0 0.61
177 INT154530 Positive_regulation of Ifng Negative_regulation of Il10 1 0.33 0.63 0.61
178 INT176365 IL12A Positive_regulation of Gene_expression of IFNA1 1 0.13 1.35 0.6
179 INT154533 Ifng Negative_regulation of Il4 1 0.11 0.62 0.6
180 INT222521 Vip Positive_regulation of Localization of Ngf 1 0.14 0.08 0.6
181 INT154531 Ifng Negative_regulation of Il10 1 0.30 0.61 0.6
182 INT83424 Binding of CD40LG and ADIPOQ 2 0.13 1 0.59
183 INT83426 ADIPOQ Negative_regulation of Binding of CD40LG 2 0.21 1 0.59
184 INT175700 Nos3 Negative_regulation of smc 1 0.01 1.05 0.59
185 INT250326 Binding of Il12a and Rpsa 1 0.09 0.93 0.59
186 INT56451 Ifng Positive_regulation of Tnf 1 0.00 1.92 0.59
187 INT87024 Positive_regulation of ZAK Positive_regulation of Localization of IFNG 2 0.05 0.81 0.58
188 INT283980 Binding of IL12A and IL23A 2 0.24 1.33 0.57
189 INT333476 IL12B Positive_regulation of Localization of AFP 1 0.03 0.26 0.57
190 INT190988 Vip Positive_regulation of Gene_expression of Scn2a1 1 0.16 0.1 0.57
191 INT110032 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il12a 1 0.36 0 0.57
192 INT187222 Binding of Vip and Vipr2 2 0.19 1.82 0.56
193 INT8402 Tnf Regulation of Gene_expression of Vip 1 0.02 0.38 0.56
194 INT73368 Ang1 Negative_regulation of Fabp6 1 0.00 0.44 0.56
195 INT81303 Tlr4 Positive_regulation of Gene_expression of Hmox1 1 0.03 0.55 0.56
196 INT34959 Pomc Positive_regulation of Localization of Vip 1 0.08 0 0.56
197 INT34958 Penk Positive_regulation of Localization of Vip 1 0.43 0 0.56
198 INT8395 Il1a Regulation of Gene_expression of Vip 1 0.01 0.38 0.56
199 INT59155 Binding of Adcyap1 and Vip 2 0.34 0.08 0.55
200 INT176371 LBR Positive_regulation of IL12A 1 0.04 1.22 0.55

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of smooth muscle cell proliferation. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of smooth muscle cell proliferation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1303 Negative_regulation of Npr1 278 0.55 35.1 156.78
2 INT4259 Positive_regulation of Npr1 262 0.70 49.37 123.11
3 INT9012 Localization of Vip 283 0.81 31.71 106.16
4 INT1635 Gene_expression of Vip 245 0.78 53.36 88.13
5 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96
6 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57
7 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14
8 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6
9 INT8388 Positive_regulation of Vip 142 0.70 39.72 67.61
10 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57
11 INT8824 Regulation of Vip 95 0.62 15.7 43.63
12 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97
13 INT65245 Gene_expression of Nos3 121 0.78 98.14 41.56
14 INT122953 Gene_expression of COMT 65 0.77 25.84 40.49
15 INT73982 Gene_expression of Hmox1 141 0.78 119.43 32.17
16 INT86780 Positive_regulation of Hmox1 145 0.70 117.09 31.18
17 INT7894 Negative_regulation of Vip 59 0.59 11.76 27.36
18 INT101120 Gene_expression of Comt 63 0.77 34.75 26.13
19 INT56224 Negative_regulation of Gene_expression of Ifng 40 0.58 23.34 25.08
20 INT43486 Positive_regulation of Ifng 52 0.69 32.71 24.77
21 INT8518 Localization of Ifng 53 0.81 36.68 24.13
22 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05
23 INT110638 Negative_regulation of COMT 43 0.59 21.03 21.05
24 INT112029 Positive_regulation of Pik3r1 90 0.67 38.76 20.95
25 INT60690 Positive_regulation of Gene_expression of Il12a 69 0.63 41.41 20.85
26 INT519 Negative_regulation of Comt 52 0.59 17.65 20.39
27 INT7017 Regulation of Npr1 45 0.52 3.38 20.05
28 INT88949 Positive_regulation of Il12a 79 0.60 47.68 19.98
29 INT25222 Positive_regulation of Gene_expression of Ifng 32 0.50 24.18 19.58
30 INT4260 Negative_regulation of Positive_regulation of Npr1 29 0.43 4.39 19.57
31 INT135629 Binding of COMT 33 0.48 16.68 19.37
32 INT19509 Localization of Ifng 55 0.78 28.25 18.67
33 INT35086 Positive_regulation of Gene_expression of Ifng 40 0.69 22.55 18.35
34 INT15148 Gene_expression of Vip 51 0.77 25.61 18.33
35 INT11525 Negative_regulation of Localization of Vip 42 0.49 6.91 18.04
36 INT83198 Positive_regulation of Nos3 78 0.64 35.69 17.71
37 INT80223 Positive_regulation of Hmox1 128 0.68 77.71 17.64
38 INT6461 Gene_expression of Npr1 35 0.75 10.38 17.58
39 INT76406 Gene_expression of Hmox1 140 0.78 85.86 17.15
40 INT24209 Negative_regulation of Ifng 37 0.57 16.52 17.15
41 INT93948 Negative_regulation of Gene_expression of Il12a 48 0.55 27.77 16.87
42 INT9299 Positive_regulation of Positive_regulation of Npr1 32 0.53 6.65 16.72
43 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
44 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58
45 INT103757 Negative_regulation of Il12a 37 0.55 21.62 16.38
46 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
47 INT112027 Gene_expression of Pik3r1 58 0.75 30.9 15.95
48 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89
49 INT10360 Positive_regulation of Ifng 33 0.68 21.73 15.19
50 INT7040 Binding of Vip 43 0.48 4.57 15.05
51 INT133549 Gene_expression of Il15 42 0.69 27.84 14.74
52 INT8989 Binding of Npr1 25 0.36 5.52 14.58
53 INT26975 Gene_expression of Adipoq 113 0.75 106.71 14.46
54 INT80228 Positive_regulation of Gene_expression of Hmox1 68 0.70 62.88 14.01
55 INT4931 Localization of IFNG 53 0.78 33.25 13.65
56 INT172171 Gene_expression of IL15 47 0.37 46.23 13.41
57 INT7532 Negative_regulation of Gene_expression of Ifng 33 0.59 18.56 13.14
58 INT101119 Negative_regulation of Comt 19 0.58 8.77 13.09
59 INT61624 Positive_regulation of Gene_expression of IL12A 50 0.56 33.07 13.07
60 INT83200 Positive_regulation of Gene_expression of Nos3 48 0.70 24.75 12.99
61 INT114420 Negative_regulation of Pik3r1 67 0.54 34.86 12.82
62 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8
63 INT121242 Positive_regulation of Gene_expression of Nos3 37 0.69 31.96 12.71
64 INT17811 Positive_regulation of Localization of Vip 35 0.67 0.85 12.67
65 INT83201 Gene_expression of NOS3 93 0.78 47.16 12.48
66 INT5057 Negative_regulation of Gene_expression of IFNG 23 0.58 8.33 12.3
67 INT17619 Regulation of COMT 12 0.45 8.46 12.22
68 INT520 Binding of Comt 24 0.48 8.98 12.21
69 INT9083 Gene_expression of Nppb 74 0.78 70.96 12.19
70 INT87239 Localization of Il12a 51 0.75 31.95 12.05
71 INT117502 Positive_regulation of Adipoq 70 0.63 40.43 12.03
72 INT9084 Positive_regulation of Nppb 74 0.70 69.77 11.85
73 INT9160 Negative_regulation of Ifng 31 0.58 16.37 11.84
74 INT73431 Positive_regulation of Nos3 82 0.65 53.22 11.61
75 INT67401 Gene_expression of Il12a 25 0.55 20.04 11.12
76 INT111223 Positive_regulation of HMOX1 47 0.70 39.14 10.92
77 INT19944 Negative_regulation of IFNG 39 0.58 22.35 10.91
78 INT133172 Gene_expression of Il12b 98 0.75 52.16 10.68
79 INT25989 Localization of Vip 31 0.68 10.53 10.35
80 INT95565 Positive_regulation of IL12A 47 0.56 33.96 10.16
81 INT13606 Negative_regulation of Negative_regulation of Npr1 13 0.40 1.21 10.01
82 INT29740 Gene_expression of ANG 55 0.78 24.53 9.86
83 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
84 INT95271 Negative_regulation of Nos3 46 0.53 24.1 9.71
85 INT30488 Regulation of Localization of Vip 16 0.44 0.58 9.41
86 INT144736 Negative_regulation of Gene_expression of COMT 13 0.58 6.47 9.28
87 INT122952 Positive_regulation of COMT 13 0.50 8.1 8.89
88 INT38173 Gene_expression of Ang 40 0.75 32.63 8.86
89 INT131788 Positive_regulation of NPPB 87 0.67 86.1 8.81
90 INT26487 Positive_regulation of Npr1 17 0.70 10.01 8.78
91 INT8424 Positive_regulation of Gene_expression of Vip 11 0.70 8.01 8.31
92 INT48725 Gene_expression of IGFBP3 128 0.78 78.83 8.19
93 INT82450 Negative_regulation of Hmox1 33 0.55 19.07 8.12
94 INT35802 Positive_regulation of Vip 16 0.40 21.5 7.95
95 INT76091 Positive_regulation of NOS3 48 0.61 18.4 7.92
96 INT172789 Regulation of Gene_expression of Nos3 15 0.53 16.23 7.86
97 INT44537 Positive_regulation of Comt 7 0.69 2.62 7.78
98 INT65246 Negative_regulation of Nos3 36 0.50 25.65 7.62
99 INT91667 Localization of IL12A 39 0.74 25.51 7.36
100 INT81293 Positive_regulation of Gene_expression of Hmox1 53 0.70 41.54 7.25
101 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
102 INT125136 Regulation of Adipoq 24 0.56 16.82 7.23
103 INT101121 Regulation of Comt 19 0.53 10.66 7.22
104 INT5326 Regulation of Ifng 12 0.55 4.56 7.19
105 INT144739 Regulation of Gene_expression of COMT 11 0.61 3.07 7.08
106 INT26489 Negative_regulation of Npr1 15 0.59 5.7 6.79
107 INT61114 Gene_expression of Ppard 23 0.75 14.98 6.62
108 INT62950 Gene_expression of NPPB 73 0.75 65.91 6.54
109 INT6459 Regulation of Negative_regulation of Npr1 10 0.53 0.16 6.44
110 INT150825 Binding of Comt 13 0.42 6.65 6.42
111 INT77945 Regulation of Gene_expression of Il12a 19 0.58 6.55 6.4
112 INT7021 Positive_regulation of Negative_regulation of Npr1 8 0.22 1.02 6.36
113 INT15147 Regulation of Vip 16 0.47 12.59 6.34
114 INT83712 Transcription of Nos3 19 0.69 13.09 6.31
115 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
116 INT50712 Gene_expression of Comt 13 0.68 6.33 6.23
117 INT74154 Transcription of Ifng 14 0.67 10.33 6.21
118 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2
119 INT146043 Positive_regulation of Gene_expression of Adipoq 39 0.67 29.93 6.12
120 INT15803 Regulation of IFNG 21 0.44 12.57 5.98
121 INT6195 Transcription of Npr1 9 0.69 3 5.94
122 INT5186 Regulation of Ifng 11 0.45 8.78 5.9
123 INT82451 Negative_regulation of HMOX1 18 0.51 13.29 5.74
124 INT83119 Negative_regulation of Gene_expression of IL12A 24 0.42 17.52 5.69
125 INT7018 Positive_regulation of Gene_expression of Npr1 10 0.59 5.09 5.66
126 INT81326 Positive_regulation of Gene_expression of Ang 17 0.67 18.5 5.46
127 INT45347 Transcription of Vip 10 0.67 2.59 5.43
128 INT13706 Localization of Npr1 10 0.59 0.83 5.42
129 INT106189 Regulation of Il12a 18 0.44 12.4 5.3
130 INT2162 Regulation of Comt 13 0.60 2.9 5.18
131 INT117499 Negative_regulation of Adipoq 28 0.56 24.15 5.07
132 INT116744 Binding of Pik3r1 22 0.36 12.77 5.01
133 INT116527 Positive_regulation of Gene_expression of HMOX1 29 0.70 25.79 4.87
134 INT49130 Positive_regulation of IGFBP3 49 0.63 27.55 4.78
135 INT11064 Positive_regulation of NPR1 24 0.49 14.63 4.78
136 INT2871 Positive_regulation of Comt 9 0.50 2.8 4.78
137 INT62132 Regulation of Gene_expression of Ifng 12 0.62 1.28 4.77
138 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
139 INT25991 Negative_regulation of Vip 11 0.53 6.76 4.64
140 INT116748 Positive_regulation of Gene_expression of Pik3r1 18 0.49 9.83 4.63
141 INT98251 Binding of IL12A 20 0.37 16.03 4.51
142 INT45159 Regulation of Nppb 16 0.54 13.57 4.46
143 INT116747 Regulation of Pik3r1 18 0.60 9.33 4.34
144 INT64338 Negative_regulation of Hmox1 16 0.56 12.72 4.2
145 INT83991 Regulation of Nos3 25 0.44 9.89 4.06
146 INT172197 Positive_regulation of Gene_expression of Comt 12 0.69 7.61 4.06
147 INT102515 Binding of Nos3 19 0.45 9.41 4.01
148 INT97096 Regulation of Hmox1 18 0.61 6.42 3.9
149 INT92653 Gene_expression of IL12B 21 0.75 17.28 3.89
150 INT83431 Binding of ADIPOQ 35 0.48 33.63 3.83
151 INT71374 Positive_regulation of Gene_expression of Il12a 5 0.22 7.49 3.8
152 INT34054 Regulation of Gene_expression of IFNG 8 0.42 3.69 3.76
153 INT16408 Negative_regulation of Nppb 14 0.53 5.49 3.74
154 INT81188 Gene_expression of Vipr2 16 0.78 4.38 3.7
155 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
156 INT83433 Positive_regulation of ADIPOQ 40 0.69 34 3.67
157 INT144231 Gene_expression of Il12b 18 0.75 12.93 3.65
158 INT133169 Positive_regulation of Il12b 25 0.49 13 3.64
159 INT172198 Protein_catabolism of Comt 7 0.88 2.78 3.6
160 INT159472 Localization of NPPB 32 0.79 33.67 3.59
161 INT28021 Positive_regulation of Adipoq 42 0.67 30.79 3.58
162 INT206598 Regulation of Gene_expression of Comt 9 0.60 6 3.56
163 INT80224 Regulation of Hmox1 19 0.32 10.53 3.52
164 INT9085 Localization of Nppb 32 0.81 15.1 3.47
165 INT174160 Binding of Il12a 19 0.24 12.61 3.4
166 INT195964 Transcription of Comt 8 0.71 4.72 3.4
167 INT70051 Transcription of IL12A 7 0.25 5.61 3.39
168 INT87027 Positive_regulation of Localization of IFNG 12 0.67 5.78 3.35
169 INT135773 Negative_regulation of Gene_expression of HMOX1 31 0.53 28.31 3.32
170 INT102634 Transcription of Hmox1 22 0.62 4.5 3.3
171 INT240127 Binding of Nppb 19 0.37 22.42 3.3
172 INT70958 Binding of NOS3 19 0.37 11.84 3.29
173 INT165911 Localization of Pik3r1 15 0.51 7.94 3.2
174 INT102034 Positive_regulation of Ppard 10 0.69 3.97 3.17
175 INT79553 Localization of Il12a 9 0.31 5.85 3.16
176 INT117501 Positive_regulation of Gene_expression of Adipoq 24 0.63 12.99 3.1
177 INT92814 Negative_regulation of NOS3 25 0.51 20.67 3.07
178 INT78467 Negative_regulation of IL12A 18 0.38 11.29 2.98
179 INT133174 Positive_regulation of Gene_expression of Il12b 29 0.15 13.04 2.92
180 INT37734 Positive_regulation of Ang 18 0.46 9.17 2.87
181 INT112758 Binding of Ppard 7 0.37 3.6 2.87
182 INT91869 Transcription of NOS3 13 0.67 6.81 2.86
183 INT114181 Negative_regulation of Positive_regulation of Il12a 7 0.34 3.65 2.82
184 INT54449 Positive_regulation of Transcription of Npr1 3 0.45 1.73 2.81
185 INT127904 Negative_regulation of Gene_expression of Hmox1 11 0.42 9.54 2.8
186 INT19203 Positive_regulation of Regulation of Vip 6 0.49 0.9 2.8
187 INT99104 Gene_expression of Npr1 5 0.78 3.31 2.8
188 INT101883 Regulation of Gene_expression of Nos3 11 0.52 6.71 2.73
189 INT67078 Binding of Ifng 7 0.48 4.84 2.73
190 INT194289 Transcription of COMT 3 0.72 3.56 2.72
191 INT90675 Negative_regulation of Gene_expression of Nos3 15 0.46 11.11 2.7
192 INT15197 Regulation of Gene_expression of Ifng 8 0.34 2.66 2.69
193 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
194 INT202257 Localization of COMT 7 0.75 2.13 2.65
195 INT204340 Localization of ADIPOQ 20 0.75 25.18 2.64
196 INT111145 Negative_regulation of Positive_regulation of Ifng 7 0.41 2.21 2.61
197 INT128983 Protein_catabolism of Comt 5 0.87 0.22 2.6
198 INT26974 Negative_regulation of Adipoq 27 0.52 26.01 2.59
199 INT91669 Negative_regulation of Localization of IFNG 5 0.57 4.1 2.58
200 INT19202 Regulation of Positive_regulation of Vip 4 0.45 2.07 2.58
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