GO:0048663

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Name neuron fate commitment
Categary Process
Go Slim No
Go Link GO:0048663
Unique Molecular Interactions 348
Total Molecular Interactions 440
Total Single Events 2618
Pain Genes Associated 40

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for neuron fate commitment. They are ordered first by their pain relevance and then by number of times they were reported for neuron fate commitment. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT170447 Binding of Pax3 and Spr 1 0.01 0.1 5.37
2 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27
3 INT113234 Binding of Pax3 and Tacr1 3 0.12 1.54 2.93
4 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
5 INT213973 Binding of Pax3 and Mthfd1 1 0.00 0.16 1.99
6 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
7 INT48790 Negative_regulation of Rtcd1 Negative_regulation of Pax3 1 0.02 0 1.59
8 INT276687 Pax3 Positive_regulation of Nkx1-1 1 0.00 0.59 1.47
9 INT118784 Thop1 Positive_regulation of Protein_catabolism of Pax3 1 0.07 0.07 1.25
10 INT351715 Pax3 Negative_regulation of Adarb1 1 0.00 0 1.19
11 INT189017 Binding of Pax3 and Lmna 1 0.14 0.42 1.16
12 INT65373 Notch1 Regulation of Oprd1 1 0.09 0 1.16
13 INT48809 Pax3 Negative_regulation of Binding of Tac1 1 0.22 0 1.16
14 INT314206 Mapk14 Positive_regulation of Pax3 1 0.08 0.67 1.15
15 INT242625 Gdnf Positive_regulation of Pax3 1 0.01 0.34 1.15
16 INT294911 Pax3 Positive_regulation of Il6 1 0.06 1.78 1.14
17 INT87222 Nrg1 Regulation of Oprd1 1 0.00 0 1.07
18 INT117908 Em Regulation of Localization of Pax3 1 0.00 0.07 1.03
19 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
20 INT49164 Binding of Pax3 and Nka1 1 0.01 0.37 1.01
21 INT49162 Nka1 Negative_regulation of Binding of Pax3 1 0.02 0.37 1.01
22 INT170449 Pax3 Positive_regulation of Spr 1 0.01 0.26 0.99
23 INT49163 Binding of Pax3 and Calca 1 0.03 0.37 0.98
24 INT4916 Binding of Pax3 and Wdyhv1 1 0.00 0 0.98
25 INT107951 Pax3 Positive_regulation of Tac1 1 0.11 1.21 0.95
26 INT196591 Binding of Lpar1 and Pax3 1 0.05 1.1 0.92
27 INT334529 Pax3 Positive_regulation of Gene_expression of Ngf 1 0.03 0.31 0.91
28 INT14626 Binding of Dpep1 and Pax3 1 0.01 0 0.87
29 INT185329 Pax3 Positive_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 0.00 0.22 0.87
30 INT213977 Pax3 Negative_regulation of Gene_expression of Il2 1 0.00 0.25 0.86
31 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
32 INT189018 Nka1 Regulation of Pax3 1 0.01 0.1 0.81
33 INT161951 Positive_regulation of TGFBR1 Positive_regulation of Gene_expression of Ngf 1 0.27 0.99 0.76
34 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
35 INT262563 Negative_regulation of Pax3 Regulation of Calca 1 0.01 0.75 0.76
36 INT294908 Pax3 Positive_regulation of Gene_expression of Il1 1 0.03 0.45 0.76
37 INT262569 Pax3 Regulation of Calca 1 0.00 0.75 0.76
38 INT314203 Nos2 Positive_regulation of Gli3 1 0.19 1.27 0.73
39 INT161950 TGFBR1 Negative_regulation of Localization of Ngf 1 0.23 1.01 0.72
40 INT294906 Binding of Pax3 and Tac4 1 0.01 1.15 0.71
41 INT68561 Binding of Gli3 and Ust 1 0.01 0.68 0.68
42 INT213971 Mthfd1 Positive_regulation of Gene_expression of Pax3 1 0.00 0.14 0.68
43 INT262570 Binding of Pax3 and Trpv1 1 0.02 1.05 0.67
44 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
45 INT170446 Pax3 Positive_regulation of Gene_expression of Spr 1 0.01 0 0.58
46 INT145431 Pax3 Positive_regulation of Positive_regulation of Ros1 1 0.02 0.07 0.57
47 INT265463 CSPG4 Negative_regulation of Gene_expression of IL6 1 0.06 1.6 0.56
48 INT302644 ARSA Positive_regulation of Gene_expression of TGFBR1 1 0.04 0.29 0.51
49 INT302647 ARSA Positive_regulation of TGFBR1 1 0.03 0.29 0.51
50 INT126336 Negative_regulation of Binding of Pax3 and Tac1 1 0.01 0.66 0.49
51 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
52 INT173475 Bcar1 Regulation of Isl1 1 0.01 0 0.47
53 INT335850 Snrpc Negative_regulation of Gene_expression of Isl1 1 0.00 1.51 0.45
54 INT148377 PDP1 Positive_regulation of NOTCH1 1 0.44 0.64 0.44
55 INT148378 CP Positive_regulation of NOTCH1 1 0.11 0.64 0.44
56 INT126337 Pax3 Positive_regulation of Gene_expression of Ifng 1 0.05 0.56 0.44
57 INT126339 Pax3 Regulation of Insrr 1 0.00 0.56 0.44
58 INT126340 Pax3 Regulation of Gene_expression of Ifng 1 0.03 0.56 0.44
59 INT294910 Pax3 Regulation of Positive_regulation of Il1 1 0.02 2.03 0.42
60 INT283714 Positive_regulation of Binding of Id2 and Homer1 1 0.08 1.34 0.42
61 INT283713 Binding of Id2 and Homer1 1 0.06 1.34 0.42
62 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
63 INT265465 CSPG4 Negative_regulation of Gene_expression of IL8 1 0.07 0.98 0.39
64 INT15104 Binding of Pax3 and Penk 1 0.01 0 0.37
65 INT297342 Binding of Gnb5 and Smo 1 0.02 1.67 0.34
66 INT309369 Ptf1a Positive_regulation of Pax2 1 0.10 0 0.3
67 INT339002 Binding of OPRD1 and GSX1 1 0.00 0 0.3
68 INT339000 Binding of LMOD1 and GSX1 1 0.01 0 0.3
69 INT208940 Pax3 Positive_regulation of Tacr1 1 0.07 0.55 0.29
70 INT208944 Pax3 Positive_regulation of Localization of Nfkb1 1 0.03 0.55 0.29
71 INT339001 GSX1 Positive_regulation of ADCY1 1 0.01 0 0.29
72 INT208941 Positive_regulation of Pax3 Positive_regulation of Tacr1 1 0.05 0.55 0.29
73 INT311918 Insrr Negative_regulation of Tgfbr1 1 0.00 0.87 0.26
74 INT311902 Acvrl1 Negative_regulation of Tgfbr1 1 0.13 0.87 0.26
75 INT342164 Binding of Csf2 and Nkx2-1 1 0.01 0.52 0.26
76 INT141634 Binding of Alb and Nrg1 1 0.00 0.3 0.26
77 INT294905 Binding of Hgf and Pax3 1 0.01 1.54 0.25
78 INT294912 Binding of Pax3 and Tacr3 1 0.01 1.54 0.25
79 INT134522 Nrg1 Regulation of Gene_expression of Mpz 1 0.60 0.29 0.25
80 INT134523 Nrg1 Positive_regulation of Gene_expression of Mpz 1 0.49 0.32 0.23
81 INT311911 Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23
82 INT297544 Pou3f3 Regulation of Notch1 1 0.06 0.41 0.2
83 INT342163 Nkx2-1 Regulation of Gene_expression of Aqp1 1 0.06 0.51 0.2
84 INT294904 Binding of Pax3 and Slc12a3 1 0.02 1.9 0.2
85 INT326575 Nrg1 Positive_regulation of Gene_expression of JUN 1 0.38 0.86 0.2
86 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
87 INT231622 Pax3 Positive_regulation of Il17a 1 0.03 1.01 0.19
88 INT333449 Binding of SMAD2 and SMAD4 1 0.23 0 0.17
89 INT244848 Lbx1 Negative_regulation of Cdca3 1 0.07 0.09 0.17
90 INT244858 Lbx1 Negative_regulation of C6 1 0.28 0.09 0.17
91 INT244840 Lbx1 Negative_regulation of C9 1 0.13 0.09 0.16
92 INT244843 Lbx1 Negative_regulation of Hoxd10 1 0.02 0.09 0.16
93 INT244850 Lbx1 Negative_regulation of Hoxd8 1 0.01 0.09 0.16
94 INT244844 Lbx1 Negative_regulation of Hoxd9 1 0.01 0.09 0.16
95 INT244842 Lbx1 Negative_regulation of Hoxc13 1 0.02 0.09 0.16
96 INT244845 Lbx1 Negative_regulation of Grcc10 1 0.09 0.09 0.16
97 INT244855 Lbx1 Negative_regulation of Dio1 1 0.03 0.09 0.16
98 INT316052 Notch1 Regulation of Binding of Cd8a 1 0.01 0.86 0.15
99 INT316053 Notch1 Regulation of Binding of Cd4 1 0.02 0.86 0.15
100 INT316050 Binding of Notch1 and Regulation of Binding of Cd8a 1 0.01 0.86 0.15
101 INT316051 Binding of Notch1 and Regulation of Binding of Cd4 1 0.02 0.86 0.15
102 INT231274 Nrg1 Regulation of Gene_expression of Akt1 1 0.19 0 0.14
103 INT161086 NOTCH3 Regulation of Notch3 1 0.51 1.06 0.14
104 INT230604 OLIG2 Negative_regulation of IRX3 1 0.34 0.54 0.14
105 INT244847 Lbx1 Positive_regulation of Skor1 1 0.47 0.08 0.13
106 INT345343 PTCH1 Regulation of Negative_regulation of SMO 1 0.09 2.3 0.13
107 INT172976 Mras Regulation of Gene_expression of Smad4 1 0.00 0.83 0.12
108 INT283719 Id2 Regulation of Regulation of Hes7 1 0.00 0.31 0.12
109 INT211996 Erbb3 Positive_regulation of Nrg1 2 0.03 0.67 0.11
110 INT283710 Binding of Id2 and Hes7 1 0.01 0.13 0.11
111 INT297546 Neurod1 Regulation of Notch1 1 0.05 0.2 0.1
112 INT262751 Binding of PTCH1 and SMO 1 0.25 1.29 0.1
113 INT231273 Binding of Egfr and Nrg1 1 0.12 0 0.09
114 INT278217 Binding of Ciita and Notch1 1 0.41 0.22 0.09
115 INT341008 Nrg1 Regulation of Binding of Erbb4 1 0.04 0 0.09
116 INT265466 CSPG4 Regulation of Phosphorylation of TP53 1 0.09 0.15 0.09
117 INT129624 Bmp7 Positive_regulation of Gene_expression of Id2 1 0.26 0.31 0.08
118 INT262939 PAX6 Regulation of CDH4 1 0.02 0.97 0.08
119 INT234222 PSEN1 Regulation of Gene_expression of NOTCH1 1 0.03 0 0.08
120 INT129625 Id2 Positive_regulation of Gene_expression of Bmp7 1 0.24 0.31 0.08
121 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
122 INT311917 Gene_expression of Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.31 0.08
123 INT262937 PAX6 Regulation of CDH8 1 0.03 0.98 0.08
124 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
125 INT262944 PAX6 Regulation of CDH6 1 0.03 0.97 0.08
126 INT283721 Binding of Lpin1 and Id2 1 0.38 0.18 0.08
127 INT201173 Sox2 Positive_regulation of Localization of Ryr2 1 0.40 0.9 0.07
128 INT129627 Bmp7 Positive_regulation of Id2 1 0.24 0.25 0.07
129 INT118416 Gata2 Positive_regulation of Transcription of Tac2 1 0.27 0.2 0.07
130 INT297246 Binding of Notch1 and Ncstn 1 0.04 0.32 0.07
131 INT298349 HES3 Positive_regulation of Shh 1 0.12 0.14 0.07
132 INT327871 Binding of Notch1 and Postn 1 0.38 1.42 0.07
133 INT201172 Sox2 Positive_regulation of Localization of Ca2 1 0.47 0.9 0.07
134 INT297244 Regulation of Binding of Notch1 and Ncstn 1 0.05 0.32 0.07
135 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
136 INT311915 Tgfbr1 Negative_regulation of Gene_expression of Mmp13 1 0.09 0.27 0.06
137 INT189557 Binding of NOTCH1 and ROBO4 1 0.01 0.22 0.06
138 INT286563 Binding of Id2 and P1Ehs1 1 0.00 0.17 0.06
139 INT286591 Binding of PKD1 and Id2 1 0.07 0.17 0.06
140 INT311906 Binding of Smad4 and Insrr 1 0.00 0.18 0.06
141 INT334686 Olig1 Regulation of Plp1 1 0.17 0.55 0.06
142 INT334689 Olig1 Regulation of Gene_expression of Cnp 1 0.20 0.55 0.06
143 INT334682 Olig1 Regulation of Cnp 1 0.09 0.55 0.06
144 INT334685 Olig1 Regulation of Gene_expression of Plp1 1 0.17 0.55 0.06
145 INT213562 Ctnnd2 Regulation of Gene_expression of Sox2 1 0.35 0.07 0.05
146 INT352623 Tpt1 Regulation of Olig2 1 0.02 0.54 0.05
147 INT352622 Olig2 Negative_regulation of Tpt1 1 0.06 0.54 0.05
148 INT210261 Bmp4 Regulation of Gene_expression of Tff3 1 0.64 0 0.05
149 INT265456 CSPG4 Regulation of ROS1 1 0.05 0.24 0.04
150 INT262757 SMO Positive_regulation of Regulation of GLI1 1 0.34 0.6 0.04
151 INT265451 CSPG4 Positive_regulation of RNGTT 1 0.03 0.24 0.04
152 INT265453 CSPG4 Regulation of Phosphorylation of ROS1 1 0.05 0.24 0.04
153 INT265457 CSPG4 Negative_regulation of IL6 1 0.06 0.24 0.04
154 INT353290 Binding of Smad2 and Smad4 1 0.20 0.08 0.04
155 INT265462 CSPG4 Negative_regulation of Positive_regulation of CASP9 1 0.07 1.2 0.04
156 INT349314 Binding of Notch1 and Notch3 1 0.11 0.67 0.04
157 INT270458 Binding of Gli1 and Smo 1 0.00 0.65 0.04
158 INT353295 Binding of Smad3 and Smad4 1 0.17 0.08 0.04
159 INT213563 Binding of Ctnnd2 and Shh 1 0.27 0.09 0.04
160 INT265461 CSPG4 Negative_regulation of Gene_expression of CASP9 1 0.06 1.2 0.04
161 INT270459 Binding of Shh and Gli1 1 0.02 0.65 0.04
162 INT341009 Nrg1 Positive_regulation of Gene_expression of Fabp7 1 0.10 0.49 0.04
163 INT231276 Erbb4 Positive_regulation of Nrg1 2 0.35 0.06 0.03
164 INT316057 Binding of Erbb4 and Nrg1 2 0.03 0.38 0.03
165 INT249898 Binding of Neurod1 and Olig2 1 0.09 0.14 0.03
166 INT352014 Shh Positive_regulation of Gene_expression of Pax1 1 0.29 0.07 0.03
167 INT283720 Id2 Negative_regulation of Transcription of Cdkn2b 1 0.18 0.11 0.03
168 INT265347 Binding of Ocln and Tgfbr1 1 0.18 0.06 0.03
169 INT265345 Binding of Tgfbr1 and Tjp1 1 0.09 0.06 0.03
170 INT316061 Positive_regulation of Binding of Erbb4 and Nrg1 1 0.03 0.38 0.03
171 INT283722 Id2 Negative_regulation of Transcription of CDKN1A 1 0.45 0.11 0.03
172 INT249889 Binding of Neurog3 and Olig2 1 0.09 0.14 0.03
173 INT280263 Binding of Smad4 and Proc 1 0.00 1.26 0.03
174 INT347165 Binding of NOTCH1 and PAX5 1 0.05 0.86 0.03
175 INT265464 CSPG4 Regulation of Gene_expression of TP53 1 0.09 0.23 0.03
176 INT249891 Binding of Atoh1 and Olig2 1 0.08 0.14 0.03
177 INT231275 Erbb4 Positive_regulation of Gene_expression of Nrg1 1 0.35 0 0.03
178 INT283712 Id2 Regulation of Gene_expression of Fos 1 0.43 0 0.03
179 INT249899 Binding of Neurog2 and Olig2 1 0.09 0.14 0.03
180 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
181 INT270462 Shh Positive_regulation of Ccnd1 1 0.10 0.6 0.03
182 INT334869 Nrg1 Positive_regulation of Phosphorylation of C3 1 0.08 0 0.03
183 INT327876 Postn Regulation of Gene_expression of Notch1 1 0.56 0.92 0.03
184 INT347163 NOTCH1 Positive_regulation of MSC 1 0.03 0.85 0.03
185 INT249901 Binding of Neurod4 and Olig2 1 0.09 0.14 0.03
186 INT213559 Binding of Egf and Shh 1 0.17 0.07 0.03
187 INT249896 Binding of Neurog1 and Olig2 1 0.09 0.14 0.03
188 INT347164 NOTCH1 Negative_regulation of Gene_expression of EBF1 1 0.03 0.85 0.03
189 INT265343 Positive_regulation of Binding of Tgfbr1 and Tjp1 1 0.12 0.06 0.03
190 INT249902 Binding of Neurod6 and Olig2 1 0.09 0.14 0.03
191 INT249900 Binding of Neurod2 and Olig2 1 0.09 0.14 0.03
192 INT265348 Positive_regulation of Binding of Ocln and Tgfbr1 1 0.25 0.06 0.03
193 INT258529 Binding of JAG1 and NOTCH1 3 0.06 2.44 0
194 INT258528 Binding of NOTCH1 and DLL1 2 0.07 1.6 0
195 INT277927 WIF1 Negative_regulation of SMAD4 1 0.23 0.37 0
196 INT244856 Lbx1 Regulation of Isl1 1 0.60 0 0
197 INT291330 Binding of ENO1 and NOTCH1 1 0.03 1.33 0
198 INT193946 Binding of Notch1 and Positive_regulation of Psen1 1 0.03 0.06 0
199 INT244841 Lbx1 Positive_regulation of Gbx1 1 0.41 0 0
200 INT290910 Pkm2 Negative_regulation of Shh 1 0.07 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for neuron fate commitment. They are ordered first by their pain relevance and then by number of times they were reported in neuron fate commitment. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT8534 Localization of Pax3 85 0.59 28.71 82.82
2 INT14624 Gene_expression of Pax3 100 0.38 33.22 69.47
3 INT4913 Binding of Pax3 52 0.28 9.57 42.67
4 INT6584 Negative_regulation of Pax3 31 0.39 14.64 27.97
5 INT28336 Positive_regulation of Pax3 37 0.33 20.94 25.66
6 INT70557 Negative_regulation of Localization of Pax3 1 0.36 1.15 17.32
7 INT70556 Positive_regulation of Localization of Pax3 9 0.34 3.13 12.11
8 INT121223 Positive_regulation of Gene_expression of Pax3 17 0.16 4.52 12.06
9 INT70555 Regulation of Pax3 13 0.35 3.62 12.05
10 INT118782 Protein_catabolism of Pax3 7 0.94 0.46 6.95
11 INT4911 Negative_regulation of Binding of Pax3 7 0.22 1.89 6.17
12 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65
13 INT68559 Negative_regulation of Gli3 5 0.37 4.56 4.93
14 INT203443 Gene_expression of Isl1 27 0.67 11.12 4.65
15 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41
16 INT15771 Gene_expression of Nrg1 34 0.67 3.16 4.11
17 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7
18 INT76815 Regulation of Gene_expression of Pax3 4 0.12 3.81 3.65
19 INT67726 Gene_expression of Notch1 36 0.75 9.77 3.54
20 INT233640 Negative_regulation of Olig2 5 0.54 2.02 3.47
21 INT170438 Negative_regulation of Gene_expression of Pax3 4 0.04 1.03 3.42
22 INT75484 Gene_expression of Tgfbr1 21 0.64 13.36 3.15
23 INT139872 Regulation of Notch1 14 0.45 7.69 2.82
24 INT119025 Gene_expression of NOTCH1 46 0.75 31.32 2.64
25 INT48807 Regulation of Binding of Pax3 2 0.13 0 2.59
26 INT126581 Positive_regulation of Gli3 6 0.35 1.59 2.48
27 INT121224 Positive_regulation of Positive_regulation of Pax3 5 0.14 2.32 2.4
28 INT334680 Negative_regulation of Olig1 1 0.43 9.5 2.32
29 INT70558 Regulation of Localization of Pax3 1 0.20 0.07 2.29
30 INT50057 Regulation of Notch1 3 0.39 0.87 2.14
31 INT132383 Gene_expression of Olig2 16 0.75 5.46 2.07
32 INT168983 Negative_regulation of Nrg1 11 0.43 3.4 2.03
33 INT126374 Gene_expression of Gli3 6 0.77 3.67 2.02
34 INT29035 Negative_regulation of Wnt1 3 0.41 1.47 2
35 INT158442 Gene_expression of Nkx2-1 21 0.59 8.47 1.99
36 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
37 INT107178 Gene_expression of Smad4 12 0.65 9.85 1.92
38 INT140036 Positive_regulation of Gene_expression of Notch1 6 0.61 2 1.86
39 INT52633 Negative_regulation of Notch1 4 0.42 2.99 1.84
40 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
41 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
42 INT209366 Negative_regulation of GSX1 1 0.42 0.92 1.72
43 INT129610 Gene_expression of Id2 7 0.74 17.07 1.69
44 INT6830 Positive_regulation of Notch1 20 0.55 7.91 1.57
45 INT244735 Gene_expression of Ascl1 12 0.58 2.48 1.54
46 INT213959 Transcription of Pax3 2 0.03 0.68 1.54
47 INT105784 Binding of Nrg1 7 0.37 1.29 1.52
48 INT163381 Transcription of Notch1 2 0.69 0.41 1.52
49 INT140245 Binding of Gli3 3 0.36 2.65 1.46
50 INT130098 Negative_regulation of NOTCH1 11 0.42 5.45 1.33
51 INT110784 Protein_catabolism of Notch1 8 0.21 2.32 1.31
52 INT189015 Negative_regulation of Positive_regulation of Pax3 1 0.12 0.31 1.31
53 INT158056 Localization of Nrg1 13 0.79 3.11 1.28
54 INT170442 Positive_regulation of Binding of Pax3 2 0.17 2.05 1.24
55 INT55599 Gene_expression of GSX1 3 0.65 3.72 1.23
56 INT216380 Gene_expression of PAX6 49 0.78 15.63 1.22
57 INT149295 Regulation of NOTCH1 10 0.13 4.26 1.22
58 INT183068 Gene_expression of SMO 2 0.17 0.27 1.2
59 INT118779 Positive_regulation of Protein_catabolism of Pax3 1 0.47 0.05 1.2
60 INT200838 Positive_regulation of Isl1 6 0.60 0.73 1.19
61 INT244768 Gene_expression of Olig1 2 0.77 3.56 1.19
62 INT110780 Localization of Notch1 2 0.06 0.47 1.19
63 INT310164 Negative_regulation of Gene_expression of Tgfbr1 9 0.40 6.11 1.17
64 INT149292 Localization of NOTCH1 7 0.54 6.11 1.14
65 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
66 INT123727 Negative_regulation of Notch1 6 0.21 1.22 1.11
67 INT265491 Gene_expression of CSPG4 16 0.58 7.27 1.07
68 INT101994 Positive_regulation of Nrg1 10 0.50 1.24 1.05
69 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
70 INT177615 Gene_expression of PAX7 20 0.65 13.5 1.03
71 INT49505 Binding of NOTCH3 6 0.47 6.4 1.03
72 INT104284 Positive_regulation of Notch3 7 0.50 5.57 0.99
73 INT6833 Binding of Notch1 4 0.36 0.05 0.94
74 INT185261 Gene_expression of OLIG2 9 0.65 5.76 0.93
75 INT118783 Negative_regulation of Protein_catabolism of Pax3 1 0.35 0.09 0.89
76 INT265313 Positive_regulation of Tgfbr1 8 0.66 2.95 0.87
77 INT142122 Regulation of Gene_expression of Bmp4 5 0.43 2.69 0.86
78 INT15247 Negative_regulation of Negative_regulation of Pax3 1 0.16 0 0.86
79 INT173472 Positive_regulation of Isl1 1 0.03 0.2 0.83
80 INT202628 Gene_expression of Wnt1 20 0.67 9.2 0.82
81 INT334674 Regulation of Olig1 1 0.27 2.13 0.82
82 INT103362 Gene_expression of Lbx1 3 0.78 0.14 0.81
83 INT210247 Positive_regulation of Bmp4 6 0.65 4.36 0.8
84 INT270447 Binding of Smo 2 0.07 2.61 0.78
85 INT93737 Gene_expression of Tgfb2 2 0.03 1.16 0.77
86 INT93736 Positive_regulation of Gene_expression of Tgfb2 2 0.02 1.16 0.77
87 INT161947 Positive_regulation of TGFBR1 2 0.52 1.6 0.76
88 INT209367 Binding of GSX1 1 0.47 0.56 0.76
89 INT139846 Protein_catabolism of Nrg1 5 0.60 1.78 0.74
90 INT172960 Negative_regulation of Gene_expression of Smad4 7 0.39 5.88 0.71
91 INT126736 Positive_regulation of Gene_expression of Nrg1 3 0.50 0.42 0.71
92 INT140037 Positive_regulation of Positive_regulation of Notch1 2 0.22 1.34 0.69
93 INT68560 Regulation of Gli3 3 0.18 1.51 0.68
94 INT243779 Negative_regulation of Gene_expression of Isl1 2 0.30 2.62 0.68
95 INT209368 Positive_regulation of GSX1 1 0.49 0.51 0.67
96 INT101726 Gene_expression of Notch3 4 0.77 4.87 0.64
97 INT96422 Gene_expression of Bmp4 18 0.69 3.26 0.63
98 INT185244 Gene_expression of Sox2 27 0.65 4.71 0.61
99 INT148387 Positive_regulation of NOTCH3 1 0.55 1.23 0.61
100 INT205957 Negative_regulation of Smo 4 0.08 2.57 0.6
101 INT226838 Transcription of Isl1 2 0.28 0.36 0.6
102 INT6831 Negative_regulation of Binding of Notch1 1 0.27 0 0.6
103 INT136920 Positive_regulation of Gene_expression of NOTCH1 12 0.49 8.25 0.59
104 INT144922 Gene_expression of TGFBR1 4 0.72 0.19 0.57
105 INT129615 Positive_regulation of Id2 2 0.66 2.22 0.57
106 INT110782 Negative_regulation of Localization of Notch1 1 0.03 0.33 0.56
107 INT55598 Regulation of GSX1 1 0.44 0.95 0.55
108 INT55600 Regulation of Gene_expression of GSX1 1 0.44 0.96 0.55
109 INT334676 Regulation of Negative_regulation of Olig1 1 0.27 2.39 0.55
110 INT149294 Regulation of Localization of NOTCH1 1 0.10 0.9 0.55
111 INT334678 Localization of Olig1 1 0.70 1.23 0.55
112 INT110785 Positive_regulation of Protein_catabolism of Notch1 1 0.05 0.33 0.55
113 INT103781 Negative_regulation of Smad4 9 0.42 4.42 0.54
114 INT135062 Transcription of Gli3 1 0.05 0 0.52
115 INT149297 Protein_catabolism of NOTCH1 2 0.15 0.87 0.51
116 INT15770 Negative_regulation of Gene_expression of Nrg1 3 0.43 1.27 0.5
117 INT142972 Gene_expression of ID2 6 0.54 5.92 0.49
118 INT206484 Localization of Shh 2 0.75 1.14 0.46
119 INT158426 Binding of NOTCH1 10 0.36 7.95 0.45
120 INT103360 Positive_regulation of Lbx1 2 0.50 0.07 0.45
121 INT170437 Regulation of Positive_regulation of Pax3 1 0.03 0 0.45
122 INT142124 Binding of Bmp4 1 0.35 0.46 0.45
123 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
124 INT71019 Negative_regulation of SMAD4 12 0.42 6.88 0.43
125 INT185255 Positive_regulation of Sox2 3 0.26 1.22 0.42
126 INT180688 Transcription of Bmp4 3 0.58 0.35 0.41
127 INT180702 Positive_regulation of Transcription of Bmp4 3 0.42 0.35 0.41
128 INT248931 Positive_regulation of Tgfb2 1 0.03 0 0.4
129 INT334681 Positive_regulation of Olig1 1 0.46 0.96 0.4
130 INT231524 Localization of PAX7 5 0.56 4.2 0.39
131 INT292484 Negative_regulation of TGFBR1 3 0.19 0.75 0.39
132 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
133 INT117564 Gene_expression of SMAD4 12 0.71 8.7 0.37
134 INT103361 Negative_regulation of Lbx1 2 0.57 0 0.37
135 INT17937 Gene_expression of Isl1 4 0.27 0.48 0.36
136 INT283683 Binding of Id2 5 0.35 0.8 0.35
137 INT254816 Negative_regulation of Tgfbr1 20 0.55 9.24 0.34
138 INT334851 Positive_regulation of Localization of Nrg1 1 0.30 0.68 0.34
139 INT265490 Localization of CSPG4 3 0.20 1.5 0.33
140 INT265480 Negative_regulation of CSPG4 5 0.32 2.37 0.31
141 INT92100 Binding of Smad4 5 0.31 2.23 0.3
142 INT258685 Regulation of Gene_expression of Notch1 2 0.40 1.45 0.3
143 INT356400 Transcription of Smo 1 0.02 0.05 0.3
144 INT85426 Transcription of CSPG4 1 0.23 1.03 0.3
145 INT202646 Gene_expression of Ptf1a 10 0.48 0.46 0.29
146 INT277474 Positive_regulation of Gene_expression of SMO 1 0.11 0 0.29
147 INT311881 Regulation of Positive_regulation of Tgfbr1 1 0.22 0.97 0.29
148 INT126059 Positive_regulation of Gata2 1 0.02 0.87 0.28
149 INT161085 Positive_regulation of Notch3 4 0.41 4.36 0.27
150 INT216120 Negative_regulation of SMO 2 0.49 3.05 0.27
151 INT78132 Binding of Isl1 1 0.16 0 0.27
152 INT349313 Positive_regulation of Gene_expression of Notch3 1 0.36 0.98 0.27
153 INT181808 Gene_expression of Pax7 18 0.54 6.22 0.26
154 INT201143 Regulation of Sox2 6 0.44 2.71 0.26
155 INT173797 Negative_regulation of Isl1 3 0.37 0.15 0.26
156 INT232795 Positive_regulation of Shh 2 0.70 3.68 0.26
157 INT173792 Negative_regulation of Negative_regulation of Isl1 1 0.08 0.15 0.26
158 INT135061 Protein_catabolism of Gli3 1 0.04 0 0.25
159 INT230631 Positive_regulation of Gene_expression of OLIG2 2 0.58 0.74 0.24
160 INT334679 Regulation of Gene_expression of Olig1 1 0.27 0.89 0.24
161 INT202632 Negative_regulation of Ptf1a 2 0.27 0 0.23
162 INT107611 Regulation of Notch3 2 0.42 0.89 0.23
163 INT244742 Gene_expression of Gata2 2 0.54 0.18 0.23
164 INT309358 Positive_regulation of Ptf1a 1 0.17 0 0.23
165 INT353967 Positive_regulation of Gene_expression of Gata2 1 0.42 0.18 0.23
166 INT316049 Regulation of Regulation of Notch1 1 0.03 0.92 0.23
167 INT309357 Negative_regulation of Positive_regulation of Ptf1a 1 0.14 0 0.23
168 INT129612 Positive_regulation of Gene_expression of Id2 4 0.67 3.61 0.22
169 INT310471 Regulation of Ascl1 1 0.34 0.19 0.22
170 INT183062 Gene_expression of SHH 12 0.65 5.28 0.21
171 INT130099 Negative_regulation of Positive_regulation of NOTCH1 4 0.43 2.56 0.21
172 INT178280 Regulation of PAX7 4 0.44 1.34 0.21
173 INT142121 Positive_regulation of Gene_expression of Bmp4 3 0.47 7 0.21
174 INT297241 Positive_regulation of Positive_regulation of Notch1 2 0.40 1.02 0.2
175 INT134477 Negative_regulation of SHH 2 0.37 1.13 0.2
176 INT348918 Negative_regulation of Negative_regulation of CSPG4 1 0.06 0.59 0.2
177 INT193945 Binding of Notch1 7 0.15 1.28 0.19
178 INT311886 Phosphorylation of Tgfbr1 1 0.40 0.7 0.19
179 INT135060 Negative_regulation of Transcription of Gli3 1 0.03 0 0.19
180 INT243778 Binding of Isl1 1 0.26 0 0.19
181 INT130096 Positive_regulation of Positive_regulation of NOTCH1 2 0.50 1.15 0.18
182 INT186648 Negative_regulation of OLIG2 1 0.23 0.75 0.18
183 INT353965 Negative_regulation of Gene_expression of Wnt1 1 0.41 0 0.18
184 INT234156 Negative_regulation of Gene_expression of Olig2 1 0.40 0.79 0.18
185 INT120085 Negative_regulation of Gene_expression of Bmp4 5 0.55 0.61 0.17
186 INT277935 Binding of SMAD4 4 0.28 1.12 0.17
187 INT146421 Binding of Notch3 2 0.35 1.94 0.17
188 INT310462 Positive_regulation of Gene_expression of Ascl1 1 0.37 0.52 0.17
189 INT136921 Gene_expression of NOTCH3 5 0.67 4.27 0.16
190 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16
191 INT98772 Localization of Isl1 2 0.65 0 0.16
192 INT253177 Negative_regulation of Gene_expression of Shh 2 0.55 0.63 0.16
193 INT64253 Localization of NOTCH3 1 0.78 0.97 0.16
194 INT64252 Negative_regulation of Localization of NOTCH3 1 0.41 0.97 0.16
195 INT310488 Binding of Ascl1 1 0.28 0.25 0.16
196 INT177614 Positive_regulation of PAX7 8 0.54 2.14 0.15
197 INT231261 Regulation of Nrg1 3 0.31 1.32 0.15
198 INT217569 Binding of Wnt1 2 0.36 1.07 0.15
199 INT110209 Localization of Notch3 2 0.75 1.82 0.15
200 INT185263 Positive_regulation of OLIG2 2 0.58 0.36 0.15
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