GO:0048664

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Name neuron fate determination
Categary Process
Go Slim No
Go Link GO:0048664
Unique Molecular Interactions 62
Total Molecular Interactions 66
Total Single Events 243
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for neuron fate determination. They are ordered first by their pain relevance and then by number of times they were reported for neuron fate determination. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT153370 LBX1 Positive_regulation of Gene_expression of Slc6a5 1 0.02 0 0.88
2 INT97949 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of CDC42 1 0.06 0.72 0.51
3 INT97953 ST3GAL3 Positive_regulation of CDC42 1 0.09 0.7 0.5
4 INT228055 WNT1 Positive_regulation of CTNND2 1 0.54 1.75 0.42
5 INT285567 Binding of IL1B and Cdc42 1 0.03 0.77 0.31
6 INT292565 MAP3K5 Positive_regulation of Positive_regulation of CDC42 1 0.02 0 0.23
7 INT244848 Lbx1 Negative_regulation of Cdca3 1 0.07 0.09 0.17
8 INT244858 Lbx1 Negative_regulation of C6 1 0.28 0.09 0.17
9 INT244840 Lbx1 Negative_regulation of C9 1 0.13 0.09 0.16
10 INT244843 Lbx1 Negative_regulation of Hoxd10 1 0.02 0.09 0.16
11 INT244850 Lbx1 Negative_regulation of Hoxd8 1 0.01 0.09 0.16
12 INT244844 Lbx1 Negative_regulation of Hoxd9 1 0.01 0.09 0.16
13 INT244842 Lbx1 Negative_regulation of Hoxc13 1 0.02 0.09 0.16
14 INT244845 Lbx1 Negative_regulation of Grcc10 1 0.09 0.09 0.16
15 INT244855 Lbx1 Negative_regulation of Dio1 1 0.03 0.09 0.16
16 INT244847 Lbx1 Positive_regulation of Skor1 1 0.47 0.08 0.13
17 INT287267 EGF Positive_regulation of CDC42 1 0.12 0.16 0.11
18 INT287887 WNT1 Positive_regulation of Localization of BMP4 1 0.04 1.13 0.1
19 INT233278 Binding of LBX1 and Tgif1 1 0.00 0.25 0.06
20 INT287877 WNT1 Positive_regulation of Localization of WISP1 1 0.03 0.56 0.05
21 INT287889 WNT1 Positive_regulation of KRT20 1 0.00 0.56 0.05
22 INT181083 Binding of Akt1 and Cdc42 1 0.00 0.79 0.03
23 INT244856 Lbx1 Regulation of Isl1 1 0.60 0 0
24 INT244841 Lbx1 Positive_regulation of Gbx1 1 0.41 0 0
25 INT244839 Lbx1 Positive_regulation of Pax2 1 0.39 0 0
26 INT244846 Lbx1 Positive_regulation of Lmx1b 1 0.40 0 0
27 INT234996 Ctnnd1 Positive_regulation of CDC42 1 0.01 0.07 0
28 INT244838 Lbx1 Negative_regulation of Foxd3 1 0.15 0 0
29 INT244853 Lbx1 Positive_regulation of Satb2 1 0.41 0 0
30 INT244849 Binding of Cish and Lbx1 1 0.21 0 0
31 INT311656 Binding of Wnt1 and Spry1 1 0.30 0.39 0
32 INT244860 Lbx1 Negative_regulation of Isl1 1 0.16 0 0
33 INT268521 Binding of WNT1 and MIR221 1 0.02 1.36 0
34 INT297855 Binding of Ndp and Wnt1 1 0.38 1.18 0
35 INT244854 Binding of Lbx1 and Skor1 1 0.31 0 0
36 INT244857 Lbx1 Positive_regulation of Lhx1 1 0.37 0 0
37 INT249149 Binding of Cdc42 and Was 1 0.08 0.18 0
38 INT244851 Lbx1 Negative_regulation of Pou4f1 1 0.38 0 0
39 INT244859 Lbx1 Regulation of Foxd3 1 0.56 0 0
40 INT181085 Binding of Cdc42 and Errfi1 1 0.08 0.67 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for neuron fate determination. They are ordered first by their pain relevance and then by number of times they were reported in neuron fate determination. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT141833 Gene_expression of WNT1 14 0.75 10.57 2.1
2 INT29035 Negative_regulation of Wnt1 3 0.41 1.47 2
3 INT141834 Negative_regulation of Gene_expression of WNT1 3 0.57 1.31 1.2
4 INT97955 Positive_regulation of CDC42 8 0.49 2.47 1.19
5 INT161682 Positive_regulation of Cdc42 8 0.53 4.55 0.9
6 INT153360 Positive_regulation of LBX1 1 0.20 0 0.88
7 INT141835 Negative_regulation of WNT1 2 0.41 1.02 0.83
8 INT202628 Gene_expression of Wnt1 20 0.67 9.2 0.82
9 INT103362 Gene_expression of Lbx1 3 0.78 0.14 0.81
10 INT180107 Regulation of Cdc42 3 0.16 0.18 0.6
11 INT97956 Negative_regulation of CDC42 3 0.27 1.58 0.55
12 INT154268 Gene_expression of LBX1 2 0.12 0.27 0.5
13 INT103360 Positive_regulation of Lbx1 2 0.50 0.07 0.45
14 INT228057 Positive_regulation of WNT1 1 0.49 1.8 0.44
15 INT103361 Negative_regulation of Lbx1 2 0.57 0 0.37
16 INT216379 Positive_regulation of Gene_expression of WNT1 5 0.30 3.1 0.34
17 INT183881 Localization of CDC42 3 0.49 1.92 0.23
18 INT183876 Regulation of CDC42 3 0.30 1.94 0.19
19 INT353965 Negative_regulation of Gene_expression of Wnt1 1 0.41 0 0.18
20 INT197290 Gene_expression of Cdc42 9 0.35 2.52 0.15
21 INT217569 Binding of Wnt1 2 0.36 1.07 0.15
22 INT206133 Binding of CDC42 3 0.25 0.8 0.12
23 INT244763 Positive_regulation of Gene_expression of Lbx1 1 0.49 0.07 0.11
24 INT266241 Regulation of Wnt1 1 0.26 0.59 0.09
25 INT197282 Positive_regulation of Gene_expression of Cdc42 3 0.26 0.12 0.08
26 INT206169 Gene_expression of CDC42 2 0.26 1.05 0.05
27 INT206167 Positive_regulation of Gene_expression of CDC42 1 0.08 0.05 0.05
28 INT304937 Transcription of Wnt1 1 0.22 0.65 0.05
29 INT233259 Binding of LBX1 2 0.01 0.63 0.04
30 INT287956 Regulation of WNT1 2 0.26 2.38 0.04
31 INT311648 Regulation of Gene_expression of Wnt1 1 0.39 0.09 0.04
32 INT287936 Regulation of Gene_expression of WNT1 1 0.20 1.06 0.04
33 INT244779 Binding of Lbx1 1 0.47 0.14 0.03
34 INT202633 Positive_regulation of Gene_expression of Wnt1 3 0.43 0.85 0
35 INT254795 Negative_regulation of Cdc42 2 0.12 1.53 0
36 INT270614 Localization of Cdc42 1 0.55 0.95 0
37 INT197294 Regulation of Gene_expression of Cdc42 1 0.13 0 0
38 INT337424 Phosphorylation of Wnt1 1 0.79 0 0
39 INT282269 Binding of Cdc42 1 0.08 0.33 0
40 INT244803 Transcription of Lbx1 1 0.67 0 0
41 INT244748 Regulation of Binding of Lbx1 1 0.44 0 0
42 INT287281 Positive_regulation of Positive_regulation of CDC42 1 0.26 0 0
43 INT282272 Positive_regulation of Binding of Cdc42 1 0.11 0.33 0
44 INT302375 Regulation of Binding of LBX1 1 0.01 0.45 0
45 INT248590 Negative_regulation of LBX1 1 0.02 0.08 0
46 INT311632 Positive_regulation of Wnt1 1 0.43 0.19 0
47 INT235058 Localization of Wnt1 1 0.64 0.56 0
48 INT244807 Regulation of Lbx1 1 0.26 0 0
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