GO:0048666

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Name neuron development
Categary Process
Go Slim No
Go Link GO:0048666
Unique Molecular Interactions 699
Total Molecular Interactions 914
Total Single Events 7987
Pain Genes Associated 44

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for neuron development. They are ordered first by their pain relevance and then by number of times they were reported for neuron development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106560 Binding of Ntf3 and Ntrk2 3 0.14 2.47 2.84
2 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
3 INT170654 Binding of Ntf3 and Ngf 1 0.38 1.66 1.54
4 INT112033 Gabrb3 Positive_regulation of Plcg1 1 0.05 0.18 1.49
5 INT112034 Gabrb3 Positive_regulation of Pik3r1 1 0.08 0.18 1.48
6 INT298283 Pou4f1 Positive_regulation of Gene_expression of Runx1 1 0.50 1.4 1.48
7 INT96707 Ntf3 Positive_regulation of Localization of SST 1 0.01 0 1.3
8 INT242623 Binding of Ntf3 and Ntrk3 5 0.22 1.31 1.29
9 INT281373 Tcf21 Regulation of Fig4 1 0.03 0.67 1.2
10 INT281383 FSCN1 Positive_regulation of Fig4 1 0.02 0.44 1.19
11 INT298272 Runx1 Positive_regulation of Gene_expression of Ntrk3 1 0.52 0.88 1.09
12 INT8416 LIF Regulation of TAC1 1 0.13 0.36 1.04
13 INT8415 LIF Regulation of VIP 1 0.13 0.36 1.04
14 INT255335 Fig4 Regulation of Phosphorylation of Nav1 1 0.01 0 1.03
15 INT56743 LIF Positive_regulation of Cck 1 0.08 0.18 1.02
16 INT298298 Calca Negative_regulation of Gene_expression of Runx1 1 0.19 0.33 1
17 INT298274 Gene_expression of Runx1 Negative_regulation of Calca 1 0.19 0.33 1
18 INT147506 Binding of Ncam1 and Gtf3a 1 0.03 0.88 0.99
19 INT56742 LIF Positive_regulation of Chat 1 0.02 0.2 0.98
20 INT147504 Binding of Ncam1 and Gdnf 1 0.31 0.87 0.98
21 INT286798 Binding of Il6st and Cntf 1 0.10 1.34 0.97
22 INT137092 Ntf3 Negative_regulation of Gene_expression of Gal 1 0.47 1.01 0.9
23 INT326455 Runx1 Positive_regulation of Gene_expression of Trpv1 1 0.45 0 0.88
24 INT188196 LIF Regulation of MAPK1 1 0.21 2.26 0.87
25 INT298289 Runx1 Negative_regulation of Ntrk2 1 0.60 1.09 0.87
26 INT298295 Runx1 Negative_regulation of Gene_expression of Ntrk1 2 0.38 0.45 0.86
27 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
28 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
29 INT261479 Fig4 Positive_regulation of Ephb1 1 0.07 0.79 0.83
30 INT98479 Lif Regulation of Gene_expression of Grin1 1 0.04 0.35 0.82
31 INT104831 Binding of GLI2 and NFKB1 1 0.08 0 0.8
32 INT220056 Binding of NTF3 and NTRK1 1 0.07 1.12 0.78
33 INT239638 Sst Regulation of Fig4 1 0.12 0.39 0.78
34 INT220063 Binding of NTF3 and NTRK2 1 0.09 1.13 0.78
35 INT215630 Fig4 Regulation of Npy 1 0.01 0.26 0.76
36 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
37 INT170658 Binding of Ntf3 and Csf2 1 0.33 0.8 0.74
38 INT161949 TGFB2 Positive_regulation of Gene_expression of Ngf 1 0.21 0.97 0.74
39 INT202909 Binding of Tacr1 and Fig4 1 0.03 0.33 0.74
40 INT149597 Lif Regulation of Regulation of Gal 1 0.30 0.69 0.73
41 INT326457 Runx1 Regulation of Mrgpra3 1 0.37 0.1 0.71
42 INT326456 Runx1 Regulation of Pip4k2b 1 0.09 0.11 0.71
43 INT149596 Lif Negative_regulation of Negative_regulation of Gal 1 0.10 0.5 0.7
44 INT246335 Fig4 Regulation of Localization of P2rx7 1 0.01 0 0.67
45 INT211915 Fig4 Positive_regulation of Mapk3 1 0.12 0.25 0.66
46 INT69205 Ntf3 Positive_regulation of Penk 1 0.06 0.06 0.66
47 INT211916 Fig4 Positive_regulation of Mapk1 1 0.13 0.25 0.66
48 INT246336 Fig4 Regulation of Localization of Nts 1 0.18 0 0.66
49 INT222253 Binding of Cxcl10 and Fig4 1 0.09 0.66 0.65
50 INT313702 Binding of Edn1 and Fig4 1 0.16 0 0.65
51 INT313703 Binding of Calca and Fig4 1 0.11 0 0.65
52 INT149899 Ihh Positive_regulation of Mmp7 1 0.04 1.69 0.65
53 INT82267 Lif Regulation of Gene_expression of Gal 1 0.40 2.76 0.62
54 INT149595 Lif Negative_regulation of Negative_regulation of Trpv1 1 0.34 0.44 0.61
55 INT79747 Ntf3 Regulation of Positive_regulation of Ntrk1 1 0.35 0 0.6
56 INT79740 Ntf3 Regulation of Positive_regulation of Ntrk2 1 0.28 0 0.6
57 INT59201 ecs Positive_regulation of Ncam1 1 0.01 0.98 0.59
58 INT280895 Runx1 Positive_regulation of Gene_expression of Ret 2 0.33 0.2 0.58
59 INT242602 Binding of Ntf3 and Ntrk1 1 0.10 0.14 0.57
60 INT281378 FSCN1 Positive_regulation of Gene_expression of Fig4 1 0.02 0.22 0.56
61 INT298278 Runx1 Negative_regulation of Gene_expression of Ntrk2 1 0.44 0.8 0.56
62 INT281648 Negative_regulation of Binding of Trpv1 and Fig4 1 0.14 0.69 0.55
63 INT222252 Positive_regulation of Binding of Ccr2 and Fig4 1 0.16 0.67 0.55
64 INT101087 NTF3 Positive_regulation of Gene_expression of IKZF1 1 0.04 0.3 0.55
65 INT281647 Binding of Trpv1 and Fig4 1 0.12 0.68 0.55
66 INT222245 Binding of Ccr2 and Fig4 1 0.12 0.67 0.55
67 INT208984 Binding of Ca2 and Fig4 1 0.02 0 0.54
68 INT291386 Cntf Regulation of Gene_expression of Gria2 1 0.11 0.13 0.53
69 INT245553 Runx1 Positive_regulation of Gene_expression of Ntrk1 2 0.45 1.41 0.52
70 INT8438 Cntf Regulation of TAC1 1 0.20 0.18 0.52
71 INT8439 Cntf Regulation of VIP 1 0.20 0.18 0.52
72 INT79746 Ntf3 Positive_regulation of Gene_expression of Sst 1 0.42 0 0.52
73 INT8440 Cntf Regulation of LIF 1 0.33 0.18 0.52
74 INT56744 CNTF Positive_regulation of Cck 1 0.08 0.09 0.51
75 INT108692 NTF3 Regulation of Gene_expression of IKZF1 1 0.69 0.7 0.49
76 INT228448 PMAIP1 Negative_regulation of Cntf 1 0.00 0.07 0.49
77 INT56736 Cntf Positive_regulation of Chat 1 0.00 0.1 0.49
78 INT228447 Negative_regulation of PMAIP1 Negative_regulation of Cntf 1 0.00 0.07 0.49
79 INT98480 Lif Positive_regulation of Pnoc 1 0.18 0.2 0.49
80 INT56745 CNTF Positive_regulation of Chat 1 0.02 0.1 0.49
81 INT98484 Lif Regulation of Gene_expression of Gal 1 0.04 0.16 0.47
82 INT149894 Ihh Positive_regulation of Localization of Mmp14 1 0.04 2.06 0.47
83 INT96709 Ntf3 Regulation of Localization of SST 1 0.01 0 0.46
84 INT98482 Lif Positive_regulation of Gene_expression of Pnoc 1 0.16 0.17 0.46
85 INT72089 TGFB2 Positive_regulation of POMC 1 0.11 0 0.46
86 INT96710 Ntf3 Regulation of BDNF 1 0.02 0 0.45
87 INT291384 Cntf Positive_regulation of Slc1a3 1 0.26 0.34 0.45
88 INT98481 Lif Regulation of Regulation of Oprl1 1 0.04 0.16 0.45
89 INT291387 Cntf Positive_regulation of Slc1a2 1 0.12 0.34 0.45
90 INT170656 Ntf3 Positive_regulation of Csf2 1 0.35 1.46 0.44
91 INT188205 OSM Regulation of LIF 1 0.09 1.12 0.43
92 INT188207 LIF Regulation of IL6 1 0.17 1.12 0.43
93 INT232293 Abat Regulation of Binding of Fig4 1 0.11 0 0.43
94 INT170657 Ntf3 Regulation of Csf2 1 0.31 0.46 0.43
95 INT326458 Runx1 Negative_regulation of Gene_expression of Calca 1 0.18 0.05 0.43
96 INT298287 Runx1 Negative_regulation of Gene_expression of Ntrk3 1 0.32 0.4 0.43
97 INT228323 PYCARD Positive_regulation of FIG4 1 0.17 0 0.42
98 INT80824 NGF Positive_regulation of NTF3 1 0.47 0.26 0.42
99 INT291393 Cntf Regulation of GTS 1 0.05 0 0.42
100 INT116938 Positive_regulation of GLI2 Positive_regulation of MAPK8 1 0.10 0.07 0.41
101 INT139654 Ntf3 Regulation of Gene_expression of Grin1 1 0.56 0.11 0.41
102 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
103 INT298286 Runx3 Regulation of Gene_expression of Runx1 1 0.47 0.36 0.41
104 INT116936 Positive_regulation of GLI2 Positive_regulation of JUN 1 0.12 0.07 0.41
105 INT298270 Gene_expression of Runx1 Positive_regulation of Ntrk3 1 0.35 0.34 0.4
106 INT330598 Binding of Il6 and Fig4 1 0.11 1.78 0.4
107 INT232292 Abat Positive_regulation of Fig4 1 0.12 0 0.4
108 INT148438 Binding of Bdnf and Ntf3 1 0.33 1.14 0.4
109 INT298261 Pou4f1 Negative_regulation of Gene_expression of Runx1 1 0.45 0.58 0.4
110 INT215629 Binding of Kcnj5 and Fig4 1 0.00 0.37 0.39
111 INT303444 Timp1 Regulation of Fig4 1 0.15 0.43 0.39
112 INT298296 Gene_expression of Runx1 Negative_regulation of Gene_expression of Ntrk2 1 0.44 0.33 0.39
113 INT321292 Fig4 Negative_regulation of Pck1 1 0.10 0.33 0.39
114 INT298266 Gene_expression of Runx1 Positive_regulation of Ntrk1 1 0.28 0.34 0.39
115 INT321301 Fig4 Negative_regulation of G6pc 1 0.07 0.33 0.39
116 INT91719 Binding of BDNF and LIF 1 0.09 1.65 0.38
117 INT266553 Ppp2r1a Positive_regulation of Fig4 1 0.00 0 0.38
118 INT266530 Ppyr1 Positive_regulation of Fig4 1 0.01 0 0.38
119 INT73537 Ntf3 Positive_regulation of Ngfr 1 0.21 0.1 0.38
120 INT215655 Fig4 Regulation of REG1A 1 0.00 0.13 0.38
121 INT91720 Binding of BDNF and CNTF 1 0.09 1.71 0.38
122 INT113040 IHH Regulation of Gene_expression of INS 1 0.12 0.37 0.37
123 INT137625 Ntf3 Positive_regulation of Atp7b 1 0.04 0 0.36
124 INT137438 Ntf3 Regulation of Sema3a 1 0.06 0.82 0.35
125 INT352231 VEGFA Negative_regulation of Cntf 1 0.04 0.22 0.34
126 INT352230 VEGFA Negative_regulation of Gene_expression of Cntf 1 0.04 0.22 0.34
127 INT177426 Izumo1 Positive_regulation of Positive_regulation of Fig4 1 0.16 0.59 0.34
128 INT137439 Ntf3 Negative_regulation of Sema3a 1 0.02 0.77 0.34
129 INT149897 Ihh Positive_regulation of Mmp14 1 0.03 0.93 0.33
130 INT149896 Ihh Regulation of Gene_expression of Col1a1 1 0.06 0.89 0.33
131 INT149895 Ihh Regulation of Localization of Mmp7 1 0.03 0.98 0.33
132 INT149902 Ihh Positive_regulation of SGCG 1 0.45 0.76 0.32
133 INT144210 Bdnf Regulation of Ntf3 1 0.20 0.78 0.3
134 INT298282 Pou4f1 Regulation of Gene_expression of Runx1 1 0.48 0.36 0.29
135 INT245563 Negative_regulation of Runx1 Regulation of Ret 1 0.39 0.76 0.29
136 INT215789 Fig4 Positive_regulation of Localization of P2rx7 1 0.03 0.53 0.29
137 INT244422 Binding of DST and Fig4 1 0.01 0.42 0.29
138 INT245556 Runx1 Regulation of Ret 1 0.56 0.76 0.29
139 INT291383 Fig4 Regulation of Gene_expression of Cntf 1 0.10 0 0.28
140 INT166605 Binding of BDNF and Ntf3 1 0.16 0.46 0.28
141 INT179425 Fig4 Regulation of Creb1 1 0.02 0.32 0.28
142 INT179423 Fig4 Regulation of Mapk3 1 0.02 0.32 0.28
143 INT63988 Cntf Regulation of Positive_regulation of Sds 1 0.22 0 0.28
144 INT166610 Binding of BDNF and Ntf3 1 0.03 0.46 0.28
145 INT149898 Ihh Regulation of Localization of Mmp14 1 0.03 1.29 0.27
146 INT321288 Fig4 Positive_regulation of Nr0b2 1 0.15 0.47 0.27
147 INT231037 Fig4 Regulation of Gene_expression of Fos 1 0.03 0.31 0.27
148 INT298280 Pou4f1 Negative_regulation of Gene_expression of Neurod4 1 0.38 0.48 0.27
149 INT351391 Binding of Sod2 and Gtf3a 1 0.00 0.18 0.27
150 INT56056 Binding of Ntf3 and Tfg 1 0.04 0.49 0.25
151 INT297547 Pou3f3 Regulation of Psen1 1 0.00 0.41 0.25
152 INT245557 Runx1 Positive_regulation of Gene_expression of Tbx15 1 0.02 0.75 0.25
153 INT245561 Gene_expression of Runx1 Positive_regulation of Gene_expression of Tbx15 1 0.02 0.8 0.25
154 INT56058 Negative_regulation of Binding of Ntf3 and Tfg 1 0.05 0.5 0.25
155 INT146217 Binding of NTF3 and Ngf 1 0.08 0.11 0.24
156 INT290847 Regulation of Binding of Stx1a and Fig4 1 0.05 0.26 0.24
157 INT146212 Binding of Ngf and Ntf3 1 0.00 0.11 0.24
158 INT210798 Ihh Positive_regulation of Itgbl1 1 0.34 0 0.23
159 INT178720 NOVA2 Regulation of Fig4 1 0.01 0 0.23
160 INT356231 Binding of Gabrb3 and Gad1 1 0.32 1.25 0.23
161 INT177425 Binding of Fig4 and Izumo1 1 0.12 0.59 0.23
162 INT245555 Runx1 Negative_regulation of Cdkn1a 1 0.29 1.17 0.23
163 INT245565 Runx1 Negative_regulation of Negative_regulation of Cdkn1a 1 0.29 1.17 0.23
164 INT157211 Binding of AGXT and WNK1 1 0.07 0.68 0.22
165 INT289998 CNTF Negative_regulation of Casp3 1 0.04 0.99 0.22
166 INT104834 Binding of GLI2 and IGKV2OR2-1 1 0.00 0 0.22
167 INT289981 Cntf Negative_regulation of Casp3 1 0.02 1.01 0.22
168 INT290846 Binding of Stx1a and Fig4 1 0.07 0.26 0.22
169 INT157212 Binding of SPTLC1 and WNK1 1 0.07 0.67 0.22
170 INT296172 Fig4 Positive_regulation of Gene_expression of NOVA2 1 0.04 0 0.22
171 INT289999 Binding of CNTF and Casp3 1 0.04 0.99 0.22
172 INT157216 Binding of SPTLC2 and WNK1 1 0.03 0.68 0.22
173 INT309513 Binding of Xrcc6 and Htt 1 0.30 3.69 0.21
174 INT290857 PPR Regulation of Fig4 1 0.02 0.45 0.21
175 INT209851 TGFB2 Negative_regulation of Gene_expression of CD36 1 0.16 0.16 0.21
176 INT261787 Positive_regulation of Bdnf Positive_regulation of Fig4 1 0.02 0.77 0.2
177 INT82268 Lif Regulation of Gene_expression of Iapp 1 0.06 0.9 0.2
178 INT203531 Pou4f1 Negative_regulation of Neurod4 1 0.46 0.54 0.2
179 INT199191 Negative_regulation of Sod2 Positive_regulation of Ros1 1 0.08 0 0.19
180 INT305533 Runx1 Positive_regulation of Il3 1 0.03 0.28 0.19
181 INT352945 Fig4 Regulation of Negative_regulation of Pik3cb 1 0.03 0.38 0.19
182 INT303937 Positive_regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
183 INT303940 Regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
184 INT175073 Fig4 Regulation of Psmc1 1 0.05 0.07 0.18
185 INT316072 Binding of Cd3e and Ncam1 1 0.01 0.4 0.18
186 INT268947 Fig4 Positive_regulation of Ros1 1 0.01 0.06 0.18
187 INT175078 Fig4 Regulation of Klk1c9 1 0.02 0.07 0.18
188 INT303938 Binding of GLI2 and CCL5 1 0.01 0 0.18
189 INT319173 TXN Positive_regulation of Gene_expression of SOD2 1 0.23 0.1 0.18
190 INT210795 Ihh Negative_regulation of Itgb1 1 0.30 0 0.17
191 INT108662 Ntf3 Positive_regulation of Trpv1 1 0.17 0.28 0.17
192 INT222426 Lif Positive_regulation of Localization of Pomc 1 0.02 0.75 0.17
193 INT330798 Fig4 Negative_regulation of Gene_expression of Accn2 1 0.03 0 0.16
194 INT303939 TRAP Positive_regulation of Protein_catabolism of GLI2 1 0.01 0 0.16
195 INT298293 Runx1 Positive_regulation of Negative_regulation of Ntrk2 1 0.52 0.54 0.16
196 INT245568 Runx1 Regulation of Gtf3a 1 0.00 0.65 0.16
197 INT303941 CCL2 Positive_regulation of Protein_catabolism of GLI2 1 0.01 0 0.16
198 INT210782 Ihh Negative_regulation of Itgbl1 1 0.31 0 0.16
199 INT298256 Runx1 Positive_regulation of Negative_regulation of Ntrk1 1 0.30 0.55 0.16
200 INT210804 Ihh Negative_regulation of Timp4 1 0.32 0 0.16

Single Events

The table below shows the top 100 pain related interactions that have been reported for neuron development. They are ordered first by their pain relevance and then by number of times they were reported in neuron development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32
2 INT133211 Gene_expression of Runx1 169 0.77 83.4 76.16
3 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81
4 INT16258 Gene_expression of Ntf3 121 0.78 53.93 59.03
5 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92
6 INT177581 Regulation of Fig4 113 0.41 39.26 27.75
7 INT171820 Localization of Fig4 144 0.65 27.38 20.88
8 INT18672 Gene_expression of Ncam1 54 0.78 36.64 18.79
9 INT170033 Positive_regulation of Gene_expression of Fig4 59 0.43 20.99 16.69
10 INT69203 Positive_regulation of Ntf3 43 0.66 19.16 16.49
11 INT97871 Gene_expression of Ntf3 47 0.78 25.9 15.94
12 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
13 INT75224 Positive_regulation of Gene_expression of Ntf3 23 0.69 11.79 13.08
14 INT16256 Regulation of Ntf3 15 0.49 9.75 13.07
15 INT174844 Binding of Fig4 81 0.41 18.03 12.87
16 INT245517 Positive_regulation of Gene_expression of Runx1 49 0.69 17.7 12.38
17 INT16255 Negative_regulation of Ntf3 21 0.51 12.92 11.93
18 INT133212 Negative_regulation of Runx1 21 0.58 11.16 11.89
19 INT173272 Phosphorylation of Fig4 45 0.48 13.85 11.42
20 INT133210 Positive_regulation of Runx1 33 0.69 18.25 10.12
21 INT245538 Negative_regulation of Gene_expression of Runx1 20 0.58 11.68 9.97
22 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
23 INT8423 Gene_expression of Cntf 29 0.69 11.69 8.4
24 INT71689 Localization of Ntf3 23 0.73 11.1 7.91
25 INT97870 Positive_regulation of Gene_expression of Ntf3 19 0.70 9.56 7.8
26 INT124297 Gene_expression of Sod2 112 0.77 65.65 7.64
27 INT171146 Negative_regulation of Gene_expression of Fig4 38 0.37 11.41 7.42
28 INT103824 Positive_regulation of SOD2 26 0.70 17.42 7.17
29 INT39282 Negative_regulation of SOD2 27 0.59 16.89 7.03
30 INT195442 Gene_expression of FIG4 23 0.65 5.13 6.92
31 INT2111 Gene_expression of LIF 34 0.77 16.82 6.76
32 INT218698 Negative_regulation of Positive_regulation of Fig4 11 0.20 6.01 6.32
33 INT169596 Transcription of Runx1 12 0.71 5.55 6.27
34 INT245515 Regulation of Runx1 14 0.61 5.07 6.22
35 INT92662 Negative_regulation of Gene_expression of Ntf3 9 0.57 7.44 6.22
36 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
37 INT16257 Regulation of Gene_expression of Ntf3 8 0.43 4 5.63
38 INT126505 Positive_regulation of Ntf3 26 0.70 9.17 4.92
39 INT245536 Regulation of Gene_expression of Runx1 11 0.58 6.22 4.88
40 INT133905 Gene_expression of Ncam1 24 0.78 10.2 4.62
41 INT173273 Positive_regulation of Phosphorylation of Fig4 16 0.30 7.3 4.62
42 INT137691 Positive_regulation of Gene_expression of Ncam1 9 0.68 2.3 4.24
43 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
44 INT56027 Positive_regulation of Ncam1 12 0.69 4.96 4.1
45 INT64170 Gene_expression of GLI2 31 0.46 14.96 3.99
46 INT79723 Positive_regulation of Sod2 34 0.70 24.61 3.92
47 INT75996 Transcription of Ntf3 13 0.67 4.03 3.88
48 INT141658 Positive_regulation of Gene_expression of Sod2 51 0.69 35.6 3.71
49 INT173751 Transcription of Fig4 31 0.46 8.28 3.7
50 INT32208 Gene_expression of Lif 23 0.74 6.23 3.7
51 INT137688 Regulation of Gene_expression of Ncam1 1 0.60 1.21 3.65
52 INT99453 Gene_expression of SOD2 25 0.77 13.28 3.6
53 INT131308 Gene_expression of Pitx3 11 0.74 3.69 3.5
54 INT82265 Gene_expression of Lif 7 0.50 6.17 3.4
55 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
56 INT81458 Positive_regulation of Cntf 11 0.47 4.18 3.18
57 INT187505 Positive_regulation of Localization of Fig4 16 0.24 1.21 3.17
58 INT76240 Positive_regulation of Lif 6 0.69 6.04 3.13
59 INT87314 Gene_expression of Htt 112 0.78 55.82 3.03
60 INT101239 Gene_expression of NTF3 9 0.76 5.91 2.97
61 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
62 INT113041 Gene_expression of IHH 9 0.78 5.83 2.87
63 INT187499 Positive_regulation of Positive_regulation of Fig4 9 0.21 3.28 2.69
64 INT174876 Regulation of Gene_expression of Fig4 18 0.39 7.83 2.44
65 INT163544 Binding of Psen1 40 0.36 15.28 2.42
66 INT33895 Positive_regulation of LIF 9 0.67 2.47 2.34
67 INT74361 Negative_regulation of Gabrb3 4 0.58 0.73 2.28
68 INT92388 Gene_expression of ALK 16 0.78 22.46 2.26
69 INT139648 Localization of Ntf3 7 0.66 3.73 2.22
70 INT137690 Negative_regulation of Gene_expression of Ncam1 3 0.50 3.37 2.18
71 INT98652 Positive_regulation of Localization of Ntf3 2 0.40 1.42 2.15
72 INT109334 Regulation of SOD2 13 0.60 7.48 2.14
73 INT228442 Localization of Cntf 8 0.63 4.2 2.12
74 INT286801 Positive_regulation of Gene_expression of Cntf 4 0.62 3.01 2.12
75 INT169597 Negative_regulation of Transcription of Runx1 3 0.58 1.92 2.07
76 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
77 INT133906 Positive_regulation of Gene_expression of Ncam1 6 0.70 1.9 2
78 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
79 INT245529 Binding of Runx1 9 0.48 4.42 1.9
80 INT44027 Positive_regulation of Lif 7 0.40 2.76 1.9
81 INT288630 Gene_expression of Cntf 6 0.75 3.99 1.89
82 INT56054 Negative_regulation of Ntf3 7 0.59 2.75 1.86
83 INT89618 Positive_regulation of Map1b 1 0.68 2.48 1.81
84 INT56028 Regulation of Ncam1 6 0.38 3.6 1.78
85 INT111070 Negative_regulation of Gene_expression of Psen1 17 0.42 9.47 1.77
86 INT90926 Positive_regulation of GLI2 12 0.45 4.99 1.74
87 INT129019 Gene_expression of Ndn 31 0.75 11.09 1.73
88 INT8422 Binding of Cntf 8 0.37 4.54 1.72
89 INT68582 Localization of CNTF 4 0.73 2.02 1.68
90 INT8421 Regulation of Cntf 6 0.44 1.46 1.67
91 INT105200 Binding of Ntf3 6 0.31 2.46 1.67
92 INT305526 Negative_regulation of Positive_regulation of Runx1 1 0.42 2.7 1.65
93 INT167145 Regulation of Gene_expression of Ntf3 6 0.54 3.4 1.64
94 INT253751 Localization of Lif 3 0.73 3.94 1.58
95 INT133904 Positive_regulation of Ncam1 7 0.50 4.01 1.57
96 INT244735 Gene_expression of Ascl1 12 0.58 2.48 1.54
97 INT126504 Regulation of Ntf3 5 0.39 4.3 1.54
98 INT50437 Regulation of LIF 6 0.44 2.12 1.53
99 INT282434 Regulation of Gene_expression of Psen1 9 0.50 2.85 1.52
100 INT124299 Negative_regulation of Gene_expression of Sod2 15 0.53 13.8 1.51
101 INT178615 Binding of SOD2 12 0.48 6.93 1.51
102 INT186022 Negative_regulation of Transcription of Fig4 6 0.28 2.09 1.5
103 INT74360 Gene_expression of Gabrb3 2 0.77 3.85 1.49
104 INT50436 Negative_regulation of Positive_regulation of LIF 1 0.37 0.33 1.42
105 INT34933 Positive_regulation of Gene_expression of LIF 6 0.67 3.41 1.38
106 INT181509 Negative_regulation of Psen1 17 0.57 11.53 1.35
107 INT104839 Negative_regulation of GLI2 8 0.35 2.7 1.24
108 INT81368 Binding of Ntf3 5 0.34 2.09 1.23
109 INT166628 Positive_regulation of Gene_expression of Becn1 2 0.67 1.03 1.23
110 INT166632 Gene_expression of Becn1 2 0.75 1.02 1.22
111 INT134061 Transcription of Sod2 5 0.68 3.46 1.19
112 INT245530 Localization of Runx1 2 0.80 1.55 1.17
113 INT140983 Gene_expression of Ihh 7 0.78 2.06 1.15
114 INT77246 Positive_regulation of WNK1 5 0.10 4.24 1.13
115 INT203483 Binding of Neurod4 1 0.36 1.96 1.09
116 INT108997 Localization of Htt 28 0.77 3.76 1.07
117 INT326445 Negative_regulation of Negative_regulation of Runx1 1 0.43 0.77 1.06
118 INT135032 Negative_regulation of SRF 1 0.49 0 1.03
119 INT71690 Negative_regulation of Negative_regulation of Ntf3 2 0.36 1.3 1.01
120 INT149594 Positive_regulation of Gene_expression of Lif 2 0.47 0.89 1
121 INT119674 Localization of GLI2 6 0.52 2.84 0.99
122 INT182322 Negative_regulation of Gene_expression of GLI2 6 0.11 2.37 0.98
123 INT81878 Gene_expression of TGFB2 3 0.42 2.02 0.97
124 INT254875 Positive_regulation of Htt 10 0.47 4.07 0.96
125 INT164400 Positive_regulation of CNTF 3 0.49 1.66 0.96
126 INT75994 Positive_regulation of Transcription of Ntf3 2 0.07 0.62 0.94
127 INT91771 Positive_regulation of Gene_expression of PSEN1 13 0.49 8.93 0.93
128 INT124300 Negative_regulation of Sod2 17 0.45 12.54 0.9
129 INT168888 Transcription of Neurod4 2 0.66 0.62 0.89
130 INT223133 Regulation of Localization of Fig4 5 0.39 0.5 0.88
131 INT64173 Regulation of Gene_expression of GLI2 4 0.37 2.89 0.88
132 INT166630 Negative_regulation of Localization of Becn1 1 0.41 0.51 0.88
133 INT298252 Regulation of Localization of Runx1 1 0.43 0.85 0.88
134 INT102819 Regulation of Lif 8 0.53 2.05 0.87
135 INT289474 Regulation of GLI2 2 0.06 1.08 0.87
136 INT166626 Localization of Becn1 1 0.76 0.5 0.87
137 INT277586 Negative_regulation of Mef2c 36 0.59 11.03 0.86
138 INT166633 Binding of Becn1 1 0.45 0.5 0.86
139 INT166629 Negative_regulation of Binding of Becn1 1 0.41 0.5 0.86
140 INT98478 Negative_regulation of Lif 3 0.42 1.29 0.84
141 INT352587 Transcription of CNTF 1 0.30 5.18 0.84
142 INT166631 Positive_regulation of Becn1 1 0.41 0.52 0.84
143 INT82262 Regulation of Lif 3 0.31 1.67 0.83
144 INT92623 Regulation of Positive_regulation of Ntf3 2 0.09 1 0.83
145 INT354449 Positive_regulation of Localization of Lif 1 0.33 1.24 0.83
146 INT154886 Gene_expression of Htt 18 0.76 15.51 0.82
147 INT237406 Positive_regulation of Binding of Psen1 1 0.29 0 0.8
148 INT103823 Positive_regulation of Gene_expression of SOD2 10 0.68 4.69 0.79
149 INT286804 Negative_regulation of Gene_expression of Cntf 2 0.38 0.71 0.79
150 INT120603 Negative_regulation of Cntf 6 0.35 3.57 0.78
151 INT93737 Gene_expression of Tgfb2 2 0.03 1.16 0.77
152 INT93736 Positive_regulation of Gene_expression of Tgfb2 2 0.02 1.16 0.77
153 INT305528 Regulation of Binding of Runx1 1 0.27 1.06 0.77
154 INT286313 Transcription of Psen1 9 0.70 2.26 0.76
155 INT104840 Binding of GLI2 6 0.08 1.89 0.72
156 INT45489 Gene_expression of SRF 5 0.77 3.29 0.71
157 INT68794 Negative_regulation of LIF 6 0.41 1.38 0.7
158 INT77247 Binding of WNK1 5 0.46 3.45 0.7
159 INT89621 Gene_expression of Map1b 1 0.76 1.48 0.7
160 INT176460 Protein_catabolism of Fig4 6 0.71 3.23 0.69
161 INT78800 Negative_regulation of Ncam1 2 0.36 0.58 0.69
162 INT96704 Negative_regulation of Positive_regulation of Ntf3 2 0.37 0 0.68
163 INT202361 Gene_expression of Mef2c 28 0.78 5.53 0.67
164 INT266894 Positive_regulation of Positive_regulation of Sod2 5 0.41 3.26 0.67
165 INT112173 Regulation of Transcription of SOD2 3 0.60 2.25 0.67
166 INT108857 Transcription of SOD2 5 0.70 3.51 0.66
167 INT2109 Negative_regulation of Gene_expression of LIF 4 0.41 0.89 0.66
168 INT115297 Positive_regulation of TGFB2 4 0.29 1.91 0.65
169 INT228327 Positive_regulation of Gene_expression of FIG4 1 0.22 0 0.64
170 INT270033 Regulation of Gene_expression of Sod2 5 0.45 2.34 0.63
171 INT70418 Negative_regulation of CNTF 1 0.58 0.62 0.63
172 INT113042 Localization of IHH 1 0.70 0.77 0.61
173 INT98239 Negative_regulation of Htt 13 0.43 7.84 0.6
174 INT249452 Localization of NTF3 4 0.48 1.21 0.6
175 INT80825 Binding of NTF3 3 0.37 0.42 0.6
176 INT171717 Regulation of Positive_regulation of Fig4 2 0.36 0.66 0.6
177 INT111960 Binding of Sod2 4 0.37 2.03 0.59
178 INT136102 Positive_regulation of Gene_expression of ALK 3 0.70 3.21 0.59
179 INT115292 Regulation of TGFB2 4 0.17 2.79 0.58
180 INT108856 Regulation of Gene_expression of SOD2 3 0.44 0.79 0.58
181 INT74362 Regulation of Gabrb3 1 0.28 0 0.58
182 INT287206 Regulation of Gene_expression of Htt 6 0.50 3.27 0.57
183 INT140984 Regulation of Ihh 5 0.54 2.81 0.56
184 INT240718 Negative_regulation of Negative_regulation of Fig4 5 0.18 1.57 0.56
185 INT215340 Localization of Htt 10 0.61 5.12 0.55
186 INT79725 Regulation of Sod2 8 0.61 4.95 0.54
187 INT216271 Positive_regulation of Protein_catabolism of Fig4 2 0.13 1.21 0.54
188 INT287204 Protein_catabolism of Htt 6 0.99 2.8 0.53
189 INT130047 Localization of TGFB2 3 0.16 3.65 0.53
190 INT217394 Regulation of Binding of PSEN1 1 0.44 1.58 0.53
191 INT154151 Positive_regulation of TP73 5 0.67 5.71 0.52
192 INT107118 Positive_regulation of ALK 4 0.49 3.64 0.52
193 INT249520 Negative_regulation of Phosphorylation of Fig4 3 0.15 0.52 0.52
194 INT251694 Regulation of Regulation of Fig4 3 0.06 0.05 0.52
195 INT286805 Positive_regulation of Localization of Cntf 1 0.40 1.3 0.52
196 INT170652 Positive_regulation of Regulation of Ntf3 1 0.43 0.99 0.51
197 INT86339 Positive_regulation of Gabrb3 1 0.14 0.14 0.51
198 INT119230 Negative_regulation of Htt 5 0.42 2.99 0.5
199 INT95163 Binding of Ncam1 3 0.32 1.02 0.5
200 INT108693 Transcription of NTF3 1 0.67 0.71 0.5
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