GO:0048667

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Name cell morphogenesis involved in neuron differentiation
Categary Process
Go Slim No
Go Link GO:0048667
Unique Molecular Interactions 112
Total Molecular Interactions 161
Total Single Events 1332
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cell morphogenesis involved in neuron differentiation. They are ordered first by their pain relevance and then by number of times they were reported for cell morphogenesis involved in neuron differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT170447 Binding of Pax3 and Spr 1 0.01 0.1 5.37
2 INT101407 Binding of Grin1 and Spr 1 0.14 0.86 3.09
3 INT142527 Binding of Slc1a2 and Slc1a3 2 0.31 0.12 2.13
4 INT352464 Gse1 Positive_regulation of Gene_expression of Slc1a3 1 0.05 1.55 1.83
5 INT187805 Ms18 Regulation of Positive_regulation of Slc1a3 1 0.26 0.87 1.12
6 INT170449 Pax3 Positive_regulation of Spr 1 0.01 0.26 0.99
7 INT116269 Binding of Myc and Mycbp2 1 0.19 0.5 0.87
8 INT250248 Binding of AQP4 and SLC1A3 1 0.11 1.55 0.77
9 INT54942 Rb1 Regulation of Gab1 1 0.02 0.39 0.59
10 INT170446 Pax3 Positive_regulation of Gene_expression of Spr 1 0.01 0 0.58
11 INT311766 INCENP Negative_regulation of Gene_expression of SLC1A3 1 0.04 0 0.55
12 INT311767 INS Negative_regulation of Gene_expression of SLC1A3 1 0.52 0 0.52
13 INT291384 Cntf Positive_regulation of Slc1a3 1 0.26 0.34 0.45
14 INT250251 Binding of SLC1A2 and SLC1A3 1 0.09 1.12 0.43
15 INT85782 Rb1 Regulation of PRKG1 1 0.00 0.38 0.37
16 INT85778 Rb1 Regulation of Prkaca 1 0.00 0.38 0.36
17 INT85779 Rb1 Regulation of Prkcg 1 0.01 0.38 0.36
18 INT250254 Binding of SLC1A3 and GOPC 1 0.02 0.44 0.35
19 INT204080 HP Negative_regulation of Phosphorylation of Rb1 1 0.00 3.53 0.34
20 INT54943 Gab1 Regulation of Rb1 1 0.02 0.2 0.31
21 INT352461 Calca Regulation of Gene_expression of Slc1a3 1 0.03 0 0.27
22 INT352451 Gse1 Regulation of Slc1a3 1 0.01 0 0.27
23 INT352455 Gse1 Regulation of Gene_expression of Slc1a3 1 0.04 0 0.27
24 INT352449 Dusp1 Regulation of Gene_expression of Slc1a3 1 0.05 0 0.27
25 INT297545 Pou3f3 Regulation of Hes1 1 0.05 0.41 0.2
26 INT119264 Binding of RB1 and PPM1E 1 0.00 0.46 0.17
27 INT221899 Rb1 Positive_regulation of Transcription of Ccl20 1 0.01 0.62 0.16
28 INT221908 Rb1 Positive_regulation of Transcription of TNIP2 1 0.01 0.62 0.16
29 INT250241 SLC1A3 Positive_regulation of AQP4 1 0.13 0.21 0.16
30 INT255258 Binding of Rb1 and Tsp1 1 0.38 0.95 0.15
31 INT310263 Rb1 Negative_regulation of Gene_expression of Tnf 1 0.07 0.97 0.15
32 INT268733 Slc1a3 Regulation of Binding of Slc1a2 1 0.39 0.23 0.14
33 INT268735 Slc1a2 Regulation of Binding of Slc1a3 1 0.39 0.23 0.14
34 INT304813 Binding of MNX1 and RT1-CE1 1 0.00 0.34 0.1
35 INT297548 Neurod1 Regulation of Hes1 1 0.05 0.2 0.1
36 INT238392 RB1 Regulation of E2F2 1 0.01 0.36 0.08
37 INT255256 Positive_regulation of Binding of Rb1 and Tsp1 1 0.50 0.48 0.08
38 INT250249 Binding of SLC1A2 and Positive_regulation of SLC1A3 1 0.12 0.69 0.08
39 INT250244 Binding of AQP4 and Positive_regulation of SLC1A3 1 0.14 0.69 0.08
40 INT198079 Ass1 Positive_regulation of Gene_expression of Slc1a3 1 0.01 0 0.07
41 INT76862 Dynll1 Positive_regulation of Rb1 1 0.37 0.1 0.06
42 INT257867 Negative_regulation of Eif4e Positive_regulation of Rb1 1 0.05 0.54 0.06
43 INT197617 Binding of S100a6 and Rb1 1 0.03 0 0.06
44 INT298806 Binding of Hdac3 and Rb1 1 0.02 0.77 0.05
45 INT250245 Binding of FCGR3A and SLC1A3 1 0.00 0.18 0.05
46 INT169962 Binding of Rb1 and E2f4 1 0.25 0.56 0.04
47 INT333848 Binding of Ccna1 and Rb1 1 0.04 0.48 0.04
48 INT197587 Ppt1 Positive_regulation of Rb1 1 0.18 0 0.03
49 INT197593 Dlat Positive_regulation of Rb1 1 0.04 0 0.03
50 INT94157 CDCP1 Negative_regulation of RB1 1 0.02 0.92 0.03
51 INT94159 Positive_regulation of CDK1 Negative_regulation of RB1 1 0.45 0.93 0.03
52 INT94158 CDK1 Negative_regulation of RB1 1 0.41 0.92 0.03
53 INT238393 Binding of E2F2 and RB1 3 0.04 0.24 0
54 INT225610 Ncoa6 Regulation of Rb1 1 0.03 0.21 0
55 INT301244 Rb1 Regulation of Hbp1 1 0.03 0.75 0
56 INT264735 Binding of Hes1 and Mir199b 1 0.08 0.93 0
57 INT334322 Binding of RB1 and TP53 1 0.34 2 0
58 INT273774 Binding of GPER and RB1 1 0.01 0.45 0
59 INT264738 Mir199b Regulation of Gene_expression of Hes1 1 0.08 0.89 0
60 INT305542 Binding of Rb1 and Trp53 1 0.00 0.9 0
61 INT169963 Positive_regulation of Binding of Rb1 and Rbl2 1 0.33 0.1 0
62 INT306825 Positive_regulation of Binding of E2F2 and RB1 1 0.04 0.05 0
63 INT264736 Hes1 Regulation of Notch2 1 0.20 0.13 0
64 INT196958 Phosphorylation of Rb1 Positive_regulation of Localization of E2f1 1 0.45 0.44 0
65 INT169959 Binding of Rb1 and Rbl2 1 0.26 0.1 0
66 INT333448 RB1 Positive_regulation of TFDP1 1 0.05 0 0
67 INT197316 Hes1 Regulation of Atoh1 1 0.01 0.14 0
68 INT330696 Phosphorylation of RB1 Positive_regulation of Gene_expression of E2F2 1 0.01 1 0
69 INT196955 Binding of E2f1 and Rb1 1 0.36 1 0
70 INT330698 PCNA Regulation of RB1 1 0.00 0.3 0
71 INT197304 Ahr Regulation of Hes1 1 0.06 0.17 0
72 INT196943 E2f1 Negative_regulation of Rb1 1 0.42 0.44 0
73 INT264731 Gene_expression of Hes1 Negative_regulation of Positive_regulation of Musd1 1 0.00 0.18 0
74 INT196961 Binding of Hmga2 and Rb1 1 0.48 6.47 0
75 INT247427 CDKN2A Negative_regulation of Negative_regulation of RB1 1 0.07 1.16 0
76 INT196950 Binding of Rb1 and E2f2 1 0.01 0.6 0
77 INT196947 Binding of Rb1 and Positive_regulation of Hmga2 1 0.50 0.3 0
78 INT264729 Mir199b Regulation of Hes1 1 0.05 0.25 0
79 INT196941 Hdac1 Negative_regulation of Rb1 1 0.27 0.44 0
80 INT196945 Rb1 Negative_regulation of Transcription of E2f1 1 0.42 0.35 0
81 INT196944 Binding of Rb1 and Hdac1 1 0.24 0.4 0
82 INT305336 TP53 Negative_regulation of Phosphorylation of RB1 1 0.29 0.96 0
83 INT197310 Hes1 Regulation of Ascl1 1 0.01 0.14 0
84 INT264725 Binding of Hes1 and Notch1 1 0.03 0.84 0
85 INT264734 Mir199b Negative_regulation of Negative_regulation of Hes1 1 0.07 0.1 0
86 INT196953 Hmga2 Negative_regulation of Rb1 1 0.59 0.35 0
87 INT264739 Mir199b Negative_regulation of Gene_expression of Hes1 1 0.07 0.82 0
88 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0
89 INT264733 Hes1 Regulation of Mir199b 1 0.05 0.43 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cell morphogenesis involved in neuron differentiation. They are ordered first by their pain relevance and then by number of times they were reported in cell morphogenesis involved in neuron differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT96533 Gene_expression of Slc1a3 72 0.78 26.85 55.31
2 INT127013 Negative_regulation of Slc1a3 37 0.54 14.16 43.97
3 INT135673 Positive_regulation of Slc1a3 23 0.57 5.45 21.45
4 INT128013 Negative_regulation of Gene_expression of Slc1a3 20 0.59 10.65 16.13
5 INT98109 Regulation of Slc1a3 15 0.52 6.87 14.43
6 INT135674 Positive_regulation of Gene_expression of Slc1a3 11 0.62 5.21 13.61
7 INT182574 Localization of Slc1a3 10 0.73 5.47 11.44
8 INT155680 Gene_expression of Slc1a3 22 0.66 6.76 7.23
9 INT127014 Negative_regulation of Negative_regulation of Slc1a3 6 0.54 2.11 6.98
10 INT136153 Binding of Slc1a3 7 0.40 2.71 6.01
11 INT170443 Gene_expression of Spr 1 0.12 0.07 5.88
12 INT135675 Positive_regulation of Negative_regulation of Slc1a3 4 0.45 0.38 5.87
13 INT135672 Negative_regulation of Positive_regulation of Slc1a3 4 0.38 0.33 5.49
14 INT165460 Gene_expression of SLC1A3 15 0.75 7.19 5.43
15 INT99536 Regulation of Gene_expression of Slc1a3 6 0.60 1.76 5.04
16 INT155681 Negative_regulation of Gene_expression of Slc1a3 5 0.36 2.26 4.86
17 INT80473 Gene_expression of Spr 5 0.46 2.76 3.86
18 INT94164 Phosphorylation of RB1 83 0.80 48.84 3.21
19 INT187803 Negative_regulation of Localization of Slc1a3 1 0.23 1.24 3.2
20 INT29929 Gene_expression of Rb1 20 0.69 5.81 3.1
21 INT101406 Regulation of Spr 3 0.25 1.32 2.95
22 INT155685 Regulation of Gene_expression of Slc1a3 2 0.50 0.77 2.85
23 INT54938 Regulation of Rb1 6 0.44 4.41 2.69
24 INT170439 Positive_regulation of Spr 1 0.10 0.3 2.67
25 INT57970 Positive_regulation of Rb1 17 0.67 7.03 2.36
26 INT73266 Gene_expression of RB1 50 0.70 29.09 2.31
27 INT195110 Positive_regulation of Gene_expression of Slc1a3 5 0.44 2.88 2.27
28 INT52865 Positive_regulation of Spr 2 0.49 0.56 2.06
29 INT127053 Transcription of Slc1a3 4 0.43 0.8 1.9
30 INT165459 Positive_regulation of SLC1A3 3 0.49 1.08 1.73
31 INT151270 Positive_regulation of Positive_regulation of Slc1a3 1 0.57 0 1.69
32 INT198066 Negative_regulation of Slc1a3 2 0.41 1.25 1.68
33 INT57971 Regulation of Rb1 5 0.41 2.36 1.66
34 INT138294 Regulation of Negative_regulation of Slc1a3 1 0.29 0.17 1.62
35 INT80469 Negative_regulation of Spr 2 0.30 1.62 1.61
36 INT155829 Negative_regulation of Protein_catabolism of Slc1a3 1 0.34 0.1 1.6
37 INT155828 Protein_catabolism of Slc1a3 1 0.80 0.1 1.6
38 INT94169 Negative_regulation of Phosphorylation of RB1 16 0.41 8.87 1.57
39 INT165457 Negative_regulation of SLC1A3 3 0.42 1.46 1.56
40 INT179752 Positive_regulation of Gene_expression of SLC1A3 3 0.17 2.35 1.56
41 INT101405 Binding of Spr 1 0.20 0.43 1.55
42 INT169907 Gene_expression of Rb1 25 0.60 21.95 1.32
43 INT116262 Gene_expression of Mycbp2 6 0.76 1.72 1.32
44 INT63905 Regulation of RB1 13 0.62 12.67 1.28
45 INT22815 Positive_regulation of RB1 20 0.49 14.58 1.26
46 INT187801 Negative_regulation of Binding of Slc1a3 1 0.26 0.25 1.26
47 INT41124 Negative_regulation of Rb1 11 0.44 3.17 1.22
48 INT170440 Positive_regulation of Gene_expression of Spr 1 0.10 0 1.21
49 INT80471 Negative_regulation of Gene_expression of Spr 1 0.22 1.19 1.16
50 INT165458 Regulation of Gene_expression of SLC1A3 1 0.23 0.26 1.08
51 INT187804 Positive_regulation of Localization of Slc1a3 1 0.26 0.84 1.06
52 INT179751 Negative_regulation of Gene_expression of SLC1A3 1 0.19 0.75 1.05
53 INT230633 Positive_regulation of MNX1 3 0.30 1.4 0.97
54 INT174188 Positive_regulation of Gene_expression of RB1 9 0.45 6.22 0.94
55 INT127051 Positive_regulation of Transcription of Slc1a3 2 0.14 0.37 0.89
56 INT101402 Positive_regulation of Gene_expression of Spr 1 0.27 0.26 0.88
57 INT101403 Transcription of Spr 1 0.29 0.26 0.88
58 INT101400 Positive_regulation of Transcription of Spr 1 0.25 0.26 0.88
59 INT191831 Positive_regulation of Slc1a3 6 0.49 3.66 0.87
60 INT147867 Localization of Spr 1 0.65 1.16 0.84
61 INT305483 Negative_regulation of MNX1 1 0.04 0.73 0.82
62 INT352660 Transcription of SLC1A3 1 0.05 0.76 0.8
63 INT101404 Regulation of Gene_expression of Spr 1 0.34 0.28 0.8
64 INT169911 Phosphorylation of Rb1 35 0.73 18.58 0.79
65 INT41123 Positive_regulation of Rb1 12 0.44 3.03 0.73
66 INT116267 Binding of Mycbp2 1 0.35 0.37 0.71
67 INT183037 Gene_expression of MNX1 12 0.53 4.27 0.69
68 INT140874 Binding of MNX1 4 0.36 0.85 0.69
69 INT179748 Regulation of SLC1A3 1 0.15 0.09 0.66
70 INT169931 Localization of Rb1 6 0.70 4.79 0.65
71 INT193196 Regulation of MNX1 2 0.19 2.53 0.64
72 INT264709 Gene_expression of Hes1 24 0.76 7.04 0.63
73 INT62266 Phosphorylation of Rb1 4 0.71 2.68 0.54
74 INT94165 Negative_regulation of RB1 30 0.52 27.29 0.51
75 INT116263 Regulation of Gene_expression of Mycbp2 1 0.60 0.58 0.5
76 INT93397 Negative_regulation of Phosphorylation of Rb1 1 0.51 0.32 0.48
77 INT352659 Positive_regulation of Transcription of SLC1A3 1 0.04 0.39 0.43
78 INT147866 Regulation of Localization of Spr 1 0.43 0.49 0.41
79 INT194993 Binding of RB1 15 0.37 10.96 0.4
80 INT196916 Negative_regulation of Rb1 13 0.42 14.29 0.4
81 INT41125 Positive_regulation of Localization of Rb1 2 0.38 0.78 0.39
82 INT41126 Localization of Rb1 2 0.61 0.78 0.39
83 INT198078 Positive_regulation of Negative_regulation of Slc1a3 1 0.40 0.15 0.38
84 INT150431 Regulation of Transcription of Slc1a3 1 0.10 0.33 0.37
85 INT198071 Regulation of Slc1a3 1 0.36 0.08 0.35
86 INT196925 Positive_regulation of Gene_expression of Rb1 4 0.45 3.16 0.33
87 INT169918 Negative_regulation of Phosphorylation of Rb1 8 0.37 6.64 0.32
88 INT197599 Transcription of Rb1 4 0.63 0.87 0.3
89 INT116266 Positive_regulation of Gene_expression of Mycbp2 1 0.68 0.4 0.29
90 INT207163 Regulation of Gene_expression of Rb1 3 0.39 1.08 0.22
91 INT230622 Negative_regulation of Gene_expression of MNX1 3 0.26 0.61 0.22
92 INT264701 Negative_regulation of Gene_expression of Hes1 1 0.42 0.73 0.18
93 INT293677 Transcription of RB1 1 0.62 0.8 0.18
94 INT206487 Binding of SLC1A3 2 0.36 0.21 0.17
95 INT169930 Binding of Rb1 15 0.43 5.91 0.16
96 INT94168 Positive_regulation of Phosphorylation of RB1 12 0.60 6.6 0.15
97 INT197627 Localization of RB1 3 0.69 4.16 0.13
98 INT314724 Regulation of Localization of RB1 1 0.15 1.25 0.13
99 INT190563 Regulation of Binding of Rb1 1 0.08 0.7 0.13
100 INT169940 Positive_regulation of Localization of Rb1 2 0.61 1.74 0.11
101 INT183057 Positive_regulation of Gene_expression of MNX1 2 0.38 0.75 0.1
102 INT257732 Regulation of Positive_regulation of RB1 2 0.39 2.35 0.09
103 INT62267 Negative_regulation of Gene_expression of Rb1 1 0.12 0.82 0.07
104 INT62265 Negative_regulation of Positive_regulation of Rb1 1 0.12 0.85 0.07
105 INT197606 Binding of Rb1 2 0.28 0.14 0.06
106 INT198065 Binding of Slc1a3 3 0.30 0 0.05
107 INT277525 Transcription of Slc1a3 1 0.59 0.09 0.05
108 INT250271 Localization of SLC1A3 1 0.20 0.77 0.04
109 INT245909 Positive_regulation of Transcription of Rb1 1 0.05 0.49 0.04
110 INT250268 Regulation of Localization of SLC1A3 1 0.12 0.77 0.04
111 INT264717 Negative_regulation of Hes1 7 0.42 0.77 0.03
112 INT236701 Negative_regulation of Gene_expression of Rb1 4 0.10 4.55 0.03
113 INT264704 Regulation of Hes1 4 0.44 1.03 0.03
114 INT169945 Positive_regulation of Phosphorylation of Rb1 4 0.41 1.75 0.03
115 INT193195 Localization of MNX1 1 0.59 1.01 0.03
116 INT298776 Regulation of Phosphorylation of Rb1 1 0.04 0.39 0.03
117 INT264702 Positive_regulation of Gene_expression of Hes1 1 0.68 1.39 0.03
118 INT174197 Negative_regulation of Gene_expression of RB1 4 0.47 4.25 0
119 INT348463 Protein_catabolism of RB1 2 0.11 2.22 0
120 INT225170 Regulation of Phosphorylation of RB1 2 0.36 1.12 0
121 INT264719 Regulation of Gene_expression of Hes1 2 0.28 0.12 0
122 INT225167 Negative_regulation of Binding of RB1 2 0.34 1.25 0
123 INT247431 Positive_regulation of Negative_regulation of RB1 2 0.45 2.58 0
124 INT196935 Negative_regulation of Binding of Rb1 1 0.38 0.24 0
125 INT264708 Transcription of Hes1 1 0.67 0.83 0
126 INT197596 Negative_regulation of Transcription of Rb1 1 0.38 0.22 0
127 INT293681 Positive_regulation of Positive_regulation of RB1 1 0.39 0.27 0
128 INT197608 Positive_regulation of Gene_expression of Rb1 1 0.44 0 0
129 INT293672 Positive_regulation of Transcription of RB1 1 0.45 0.4 0
130 INT264705 Binding of Hes1 1 0.35 0.07 0
131 INT196910 Positive_regulation of Binding of Rb1 1 0.45 0.81 0
132 INT273783 Regulation of Gene_expression of RB1 1 0.29 0.67 0
133 INT264706 Positive_regulation of Hes1 1 0.40 0.14 0
134 INT204055 Positive_regulation of Negative_regulation of Rb1 1 0.03 0.55 0
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