GO:0048730

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Name epidermis morphogenesis
Categary Process
Go Slim No
Go Link GO:0048730
Unique Molecular Interactions 38
Total Molecular Interactions 45
Total Single Events 217
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for epidermis morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported for epidermis morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT183176 Binding of FGFR2 and NUDT6 1 0.05 1.07 0.84
2 INT207540 Tfap2a Regulation of Oprm1 1 0.13 0.06 0.7
3 INT135207 Gmeb1 Regulation of Gene_expression of Tfap2a 1 0.07 0.48 0.69
4 INT135206 Ighen Regulation of Gene_expression of Tfap2a 1 0.06 0.48 0.69
5 INT135202 Tfap2a Regulation of Gene_expression of Ighen 1 0.06 0.48 0.69
6 INT135213 Tfap2a Regulation of Gene_expression of Nfkb1 1 0.02 0.48 0.69
7 INT135211 Nfkb1 Regulation of Gene_expression of Tfap2a 1 0.02 0.48 0.69
8 INT135204 Tfap2a Regulation of Gene_expression of Gmeb1 1 0.10 0.48 0.69
9 INT207543 Tfap2a Regulation of Qsox1 1 0.04 0.06 0.67
10 INT244028 Positive_regulation of Binding of Cacnb3 and Tfap2a 1 0.01 0.24 0.49
11 INT244037 Positive_regulation of Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
12 INT244000 Positive_regulation of Binding of Tfap2a and Dnm1 1 0.04 0.24 0.49
13 INT244035 Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
14 INT243997 Binding of Tfap2a and Dnm1 1 0.03 0.24 0.49
15 INT244060 Binding of Cacnb3 and Tfap2a 1 0.00 0.24 0.49
16 INT301054 Tfap2a Regulation of Gene_expression of Faslg 1 0.00 1.23 0.34
17 INT285567 Binding of IL1B and Cdc42 1 0.03 0.77 0.31
18 INT65267 Igf1 Regulation of Gene_expression of Plod3 1 0.07 0 0.13
19 INT65271 Igf1 Positive_regulation of Gene_expression of Plod3 1 0.12 0 0.13
20 INT303561 Binding of Fgf7 and Fgfr2 1 0.42 0.88 0.07
21 INT303560 Binding of Fgfr2 and Fgf22 1 0.41 0.89 0.07
22 INT303562 Binding of Fgf10 and Fgfr2 1 0.40 0.88 0.07
23 INT250855 Binding of Fgfr2 and Fgf8 1 0.12 0.3 0.05
24 INT303558 Binding of Fgfr2 and Dysf 1 0.01 0.44 0.03
25 INT303563 Binding of Fgf10 and Dysf 1 0.00 0.44 0.03
26 INT181083 Binding of Akt1 and Cdc42 1 0.00 0.79 0.03
27 INT183091 Binding of FGF2 and FGFR2 1 0.03 0.79 0
28 INT273949 Binding of Crem and Smarca4 1 0.01 0 0
29 INT245820 Binding of Sp1 and Tfap2a 1 0.03 0.64 0
30 INT337408 Binding of TCF4 and KLF4 1 0.09 0 0
31 INT351982 Smarca4 Positive_regulation of Stk11 1 0.05 0.58 0
32 INT249149 Binding of Cdc42 and Was 1 0.08 0.18 0
33 INT245828 Binding of VEGFA and Tfap2a 1 0.01 0.64 0
34 INT202675 Fgf10 Positive_regulation of Fgfr2 1 0.45 0.07 0
35 INT181085 Binding of Cdc42 and Errfi1 1 0.08 0.67 0
36 INT183089 Positive_regulation of Binding of FGF2 and FGFR2 1 0.04 0.4 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for epidermis morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported in epidermis morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT207521 Gene_expression of Tfap2a 7 0.48 1.89 1.45
2 INT76890 Gene_expression of FGFR2 42 0.65 13.91 1.08
3 INT84511 Positive_regulation of Tfap2a 3 0.27 0.72 1.04
4 INT243974 Binding of Tfap2a 7 0.18 1.36 0.93
5 INT161682 Positive_regulation of Cdc42 8 0.53 4.55 0.9
6 INT183182 Negative_regulation of FGFR2 2 0.29 1.25 0.84
7 INT221796 Positive_regulation of Gene_expression of Tfap2a 2 0.10 1.19 0.83
8 INT207535 Transcription of Tfap2a 3 0.31 0.98 0.74
9 INT135197 Gene_expression of Tfap2a 1 0.45 0.48 0.69
10 INT158136 Binding of FGFR2 9 0.26 4.5 0.63
11 INT180107 Regulation of Cdc42 3 0.16 0.18 0.6
12 INT207529 Localization of Tfap2a 2 0.34 0.13 0.6
13 INT296583 Gene_expression of Fgf10 3 0.59 2.64 0.57
14 INT243970 Phosphorylation of Tfap2a 2 0.25 0.56 0.56
15 INT296594 Regulation of Fgf10 1 0.15 1.53 0.56
16 INT146778 Negative_regulation of Fgfr2 1 0.32 0.66 0.48
17 INT202626 Negative_regulation of Fgfr2 2 0.41 2.48 0.42
18 INT65266 Gene_expression of Plod3 1 0.17 0 0.3
19 INT176080 Gene_expression of Fgfr2 4 0.68 2.34 0.24
20 INT223739 Binding of Fgfr2 3 0.30 0.94 0.22
21 INT65264 Positive_regulation of Gene_expression of Plod3 1 0.11 0 0.18
22 INT162939 Binding of Tfap2a 1 0.26 0.34 0.17
23 INT162940 Negative_regulation of Tfap2a 1 0.32 0.34 0.17
24 INT162941 Negative_regulation of Binding of Tfap2a 1 0.32 0.34 0.17
25 INT197290 Gene_expression of Cdc42 9 0.35 2.52 0.15
26 INT99718 Positive_regulation of Gene_expression of FGFR2 9 0.49 4.47 0.12
27 INT282593 Gene_expression of KLF4 8 0.61 1.09 0.09
28 INT197282 Positive_regulation of Gene_expression of Cdc42 3 0.26 0.12 0.08
29 INT303546 Binding of Fgfr2 1 0.46 0.74 0.06
30 INT282606 Positive_regulation of Gene_expression of KLF4 2 0.54 0.8 0.04
31 INT260760 Positive_regulation of Fgf10 2 0.53 0.43 0.03
32 INT260908 Positive_regulation of Smarca4 2 0.21 0.53 0.03
33 INT303535 Positive_regulation of Gene_expression of Fgf10 1 0.53 0.34 0.03
34 INT303525 Localization of Fgfr2 1 0.72 0.28 0.03
35 INT282592 Regulation of KLF4 1 0.26 0.14 0.03
36 INT303547 Positive_regulation of Negative_regulation of Fgfr2 1 0.48 1.07 0.03
37 INT207729 Regulation of FGFR2 4 0.22 2.35 0
38 INT238985 Positive_regulation of FGFR2 3 0.49 1.19 0
39 INT99716 Transcription of FGFR2 2 0.34 0.22 0
40 INT305351 Positive_regulation of Regulation of FGFR2 2 0.37 0.97 0
41 INT254795 Negative_regulation of Cdc42 2 0.12 1.53 0
42 INT99715 Regulation of Gene_expression of FGFR2 2 0.22 0.19 0
43 INT294852 Negative_regulation of KLF4 2 0.20 0.49 0
44 INT303555 Negative_regulation of Gene_expression of FGFR2 2 0.41 0.31 0
45 INT294855 Negative_regulation of Gene_expression of KLF4 1 0.13 0.49 0
46 INT202623 Negative_regulation of Gene_expression of Fgfr2 1 0.32 0 0
47 INT319036 Gene_expression of Fgfr2 1 0.48 0.08 0
48 INT270614 Localization of Cdc42 1 0.55 0.95 0
49 INT197294 Regulation of Gene_expression of Cdc42 1 0.13 0 0
50 INT337469 Binding of KLF4 1 0.17 0 0
51 INT282269 Binding of Cdc42 1 0.08 0.33 0
52 INT294846 Positive_regulation of Negative_regulation of KLF4 1 0.15 0.49 0
53 INT339596 Localization of KLF4 1 0.26 0 0
54 INT282272 Positive_regulation of Binding of Cdc42 1 0.11 0.33 0
55 INT260913 Negative_regulation of Smarca4 1 0.18 0.29 0
56 INT99717 Positive_regulation of Transcription of FGFR2 1 0.10 0.08 0
57 INT183117 Positive_regulation of Binding of FGFR2 1 0.09 0.81 0
58 INT273916 Binding of Smarca4 1 0.01 0 0
59 INT303524 Positive_regulation of Fgfr2 1 0.66 0.22 0
60 INT311630 Negative_regulation of Tfap2a 1 0.34 0.23 0
61 INT294861 Positive_regulation of KLF4 1 0.15 0.49 0
62 INT319128 Positive_regulation of Binding of Tfap2a 1 0.23 0.5 0
63 INT311626 Negative_regulation of Gene_expression of Tfap2a 1 0.34 0.29 0
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