GO:0048753

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Name pigment granule organization
Categary Process
Go Slim No
Go Link GO:0048753
Unique Molecular Interactions 211
Total Molecular Interactions 283
Total Single Events 3361
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for pigment granule organization. They are ordered first by their pain relevance and then by number of times they were reported for pigment granule organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
2 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
3 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
4 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
5 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
6 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
7 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
8 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
9 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
10 INT302839 MIR15A Negative_regulation of Bcl2 1 0.15 1.41 0.47
11 INT238639 Cd86 Negative_regulation of Negative_regulation of Bcl2 1 0.01 0.97 0.46
12 INT112772 Binding of Bcl2 and SGSM3 1 0.02 0.69 0.45
13 INT116609 Lnpep Negative_regulation of Bcl2 1 0.05 0.62 0.43
14 INT116606 Lnpep Regulation of Gene_expression of Bcl2 1 0.07 0.62 0.43
15 INT116607 Lnpep Negative_regulation of Gene_expression of Bcl2 1 0.10 0.62 0.43
16 INT309143 Dlat Positive_regulation of Bcl2 1 0.06 1.04 0.42
17 INT309152 Dlat Positive_regulation of Gene_expression of Bcl2 1 0.04 1.05 0.42
18 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
19 INT155062 Csf2 Positive_regulation of Transcription of Bcl2 1 0.31 2.91 0.36
20 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35
21 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34
22 INT155060 Stat3 Negative_regulation of Bcl2 1 0.21 3.7 0.33
23 INT242398 Cyp19a1 Positive_regulation of Bcl2 1 0.00 1.28 0.3
24 INT218928 Cyp3a23/3a1 Regulation of Transcription of Bcl2 1 0.00 0.56 0.28
25 INT260837 NRP2 Negative_regulation of Negative_regulation of Bcl2 1 0.00 0.9 0.28
26 INT172905 Binding of Bad and Bcl2 3 0.08 6.46 0.27
27 INT237927 BCL2 Positive_regulation of BAX 2 0.24 2.22 0.26
28 INT237928 BCL2 Positive_regulation of FAS 1 0.02 1.41 0.26
29 INT272157 Gh1 Negative_regulation of Bcl2 1 0.23 1.2 0.26
30 INT272158 Gh1 Regulation of Bcl2 1 0.15 1.2 0.26
31 INT237925 BCL2 Positive_regulation of Protein_catabolism of PARP1 1 0.02 1.42 0.26
32 INT260840 NRP2 Positive_regulation of Gene_expression of Bcl2 1 0.00 0.85 0.24
33 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23
34 INT176133 AKT1 Regulation of BCL2 2 0.12 1.84 0.17
35 INT285026 Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
36 INT285022 Regulation of Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
37 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17
38 INT155233 TXNIP Regulation of BCL2 1 0.23 0.15 0.17
39 INT285024 Bcl2 Regulation of Bak1 1 0.09 0.71 0.17
40 INT229203 Binding of Bcl2 and Cyp2c11 1 0.36 1.2 0.17
41 INT155068 Csf2 Negative_regulation of Bcl2 1 0.12 1.88 0.17
42 INT347445 CD99 Positive_regulation of BCL2 1 0.17 0.95 0.16
43 INT292750 Akt1 Positive_regulation of Bcl2 1 0.01 1.67 0.15
44 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15
45 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
46 INT95104 TGFBR2 Positive_regulation of BCL2 1 0.08 0.61 0.14
47 INT309139 Edc4 Positive_regulation of Bcl2 1 0.03 0.12 0.13
48 INT148594 Binding of BCL2 and CD34 1 0.39 1.17 0.13
49 INT309142 Edc4 Regulation of Bcl2 1 0.02 0.12 0.13
50 INT246016 Negative_regulation of Timp1 Negative_regulation of Gene_expression of Bcl2 1 0.03 1.07 0.13
51 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
52 INT348542 BCL2 Negative_regulation of NLRP1 1 0.07 2.02 0.13
53 INT246017 Timp1 Negative_regulation of Gene_expression of Bcl2 1 0.03 1.07 0.13
54 INT172899 Binding of Bcl2 and Bcl2l1 3 0.02 5.54 0.12
55 INT178101 EDN1 Negative_regulation of Phosphorylation of BCL2 1 0.03 1 0.12
56 INT305194 Bcl2 Positive_regulation of Epo 1 0.06 0.29 0.12
57 INT273063 Negative_regulation of Fas Negative_regulation of Positive_regulation of Bcl2 1 0.01 0.72 0.11
58 INT221684 Binding of Bcl2 and FRTS 1 0.01 1.19 0.11
59 INT265888 BCL2 Regulation of Gene_expression of BAD 1 0.04 1.08 0.1
60 INT265890 BCL2 Regulation of Gene_expression of BAX 1 0.04 1.08 0.1
61 INT239643 Binding of BCL2 and BCL2L11 3 0.16 2.26 0.09
62 INT282094 Apoa2 Negative_regulation of BCL2 1 0.06 1.15 0.09
63 INT275183 Bad Positive_regulation of Gene_expression of Bcl2 1 0.08 0.63 0.09
64 INT265887 IGF1 Negative_regulation of BCL2 1 0.09 1.02 0.09
65 INT294637 Bcl2a1a Positive_regulation of Gene_expression of Bcl2 1 0.15 0.97 0.09
66 INT204300 Bcl2 Negative_regulation of Positive_regulation of Bak1 1 0.02 1.13 0.09
67 INT350908 Binding of Bcl2 and Twist1 1 0.04 1.9 0.08
68 INT201456 Hmox1 Positive_regulation of Gene_expression of Bcl2 1 0.06 0.74 0.08
69 INT204299 Bcl2 Negative_regulation of Localization of Aifm1 1 0.06 1.22 0.07
70 INT297733 Cbr1 Regulation of Gene_expression of Bcl2 1 0.05 0.94 0.07
71 INT302177 PTGER2 Positive_regulation of BCL2 1 0.04 2.08 0.06
72 INT352299 Regulation of Binding of BCL2 and VIM 1 0.10 1.07 0.06
73 INT352298 Binding of BCL2 and VIM 1 0.09 1.06 0.06
74 INT341375 Sod2 Regulation of Bcl2 1 0.08 1.96 0.05
75 INT190824 Binding of Cl and Bcl2 1 0.02 1.4 0.05
76 INT333252 Positive_regulation of Binding of Bcl2 and Mcl1 1 0.03 0.88 0.04
77 INT268664 Ptger2 Positive_regulation of Bcl2 1 0.02 0.9 0.04
78 INT333245 Binding of Bcl2 and Bcl2l11 1 0.03 0.87 0.04
79 INT268666 Ptger2 Positive_regulation of Gene_expression of Bcl2 1 0.02 0.9 0.04
80 INT350905 Binding of Bcl2 and Pcsk4 1 0.03 0.96 0.04
81 INT333253 Binding of Bcl2 and Mcl1 1 0.02 2.14 0.04
82 INT250025 Map3k1 Positive_regulation of Regulation of Bcl2 1 0.01 1.1 0.04
83 INT172902 Binding of Bax and Bcl2 5 0.30 3.19 0.03
84 INT192164 Binding of BAK1 and BCL2 3 0.04 2.8 0.03
85 INT192167 Negative_regulation of Binding of BAK1 and BCL2 2 0.05 1.89 0.03
86 INT288538 Il2 Positive_regulation of Gene_expression of Bcl2 1 0.04 1.96 0.03
87 INT217148 MIR21 Regulation of BCL2 1 0.32 0.98 0.03
88 INT101159 Gene_expression of Bcl2 Positive_regulation of Gene_expression of CHAT 1 0.31 0.96 0.03
89 INT229204 Olr1254 Negative_regulation of Gene_expression of Bcl2 1 0.02 0.18 0.03
90 INT333259 Bcl2 Regulation of Bax 1 0.03 0.32 0.03
91 INT172894 Negative_regulation of Lox Negative_regulation of Gene_expression of Bcl2 1 0.03 1.12 0.03
92 INT220445 Bcl2 Negative_regulation of Positive_regulation of Casp9 1 0.01 1.37 0.03
93 INT333262 Bcl2 Regulation of Bak1 1 0.04 0.31 0.03
94 INT282995 Binding of Bcl2 and Becn1 21 0.03 9.8 0
95 INT283013 Binding of Bak1 and Bcl2 4 0.06 1.03 0
96 INT178861 Binding of BAX and BCL2 3 0.27 3.07 0
97 INT292454 Binding of BAD and BCL2 2 0.03 1.73 0
98 INT144032 STAT3 Regulation of BCL2 2 0.07 0.86 0
99 INT217150 MIR16-2 Regulation of BCL2 2 0.09 1.89 0
100 INT217137 MIR15B Regulation of BCL2 2 0.15 1.88 0
101 INT295047 Binding of Bcl2 and Nr4a1 1 0.04 0.96 0
102 INT254089 EPO Regulation of Gene_expression of Bcl2 1 0.03 0.63 0
103 INT285031 Binding of Bcl2 and Bcl2l1 1 0.27 0.1 0
104 INT321406 VEGFA Regulation of BCL2 1 0.01 0.75 0
105 INT295046 Bcl2 Regulation of Gene_expression of Nr4a1 1 0.02 0.92 0
106 INT292503 Mlph Regulation of Gene_expression of BCL2 1 0.00 0.4 0
107 INT253474 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Bcl2 1 0.04 1.27 0
108 INT191058 Binding of Bcl2 and Positive_regulation of Gene_expression of Bax 1 0.21 0.49 0
109 INT333688 Trp53 Positive_regulation of Bcl2 1 0.45 2.51 0
110 INT348531 Binding of BCL2 and BECN1 1 0.06 0.43 0
111 INT221240 Akt1 Positive_regulation of Phosphorylation of Bcl2 1 0.00 0.89 0
112 INT191062 Esr1 Regulation of Gene_expression of Bcl2 1 0.12 0.73 0
113 INT267255 Bcl2 Positive_regulation of Gene_expression of Ptprj 1 0.04 0.63 0
114 INT191061 Akt1 Positive_regulation of Bcl2 1 0.41 0.33 0
115 INT283003 Igkv1-131 Regulation of Binding of Bcl2 1 0.06 0 0
116 INT280566 Binding of ARAF and BCL2 1 0.02 0.69 0
117 INT283009 Binding of Bcl2 and Pdss2 1 0.03 0.56 0
118 INT100424 Bcl2 Regulation of Pcbd1 1 0.14 0.06 0
119 INT202507 Nfasc Positive_regulation of Gene_expression of Bcl2 1 0.10 0.7 0
120 INT283000 Negative_regulation of Binding of Bcl2 and Becn1 1 0.03 0.71 0
121 INT315060 PAR4 Regulation of BCL2 1 0.53 0.48 0
122 INT327972 Negative_regulation of BCL2 Positive_regulation of BAX 1 0.22 0.82 0
123 INT285028 Binding of Bcl2 and Bax 1 0.32 0.1 0
124 INT268516 Gene_expression of MIR16-2 Positive_regulation of Gene_expression of BCL2 1 0.00 1.15 0
125 INT335953 Binding of BCL2 and Bad 1 0.14 0.37 0
126 INT198021 Binding of BCL2 and MCL1 1 0.17 2.88 0
127 INT331231 Binding of Bcl2 and Mapk8 1 0.01 0.77 0
128 INT283011 Binding of Bcl2 and Igkv1-131 1 0.05 0.8 0
129 INT296670 Binding of Bcl2 and Vim 1 0.00 1.31 0
130 INT191065 Binding of Bcl2 and Negative_regulation of Phosphorylation of Akt1 1 0.22 1.02 0
131 INT292458 Negative_regulation of Binding of BAD and BCL2 1 0.01 0.81 0
132 INT327977 TNFRSF11A Regulation of BCL2 1 0.05 0.67 0
133 INT337707 Naf1 Regulation of Gene_expression of Bcl2 1 0.11 0.57 0
134 INT191059 Bcl2 Positive_regulation of Localization of Il12a 1 0.16 0.77 0
135 INT202503 Gtf3a Positive_regulation of Positive_regulation of Bcl2 1 0.02 0.35 0
136 INT286030 Creb1 Regulation of Transcription of Bcl2 1 0.07 0.34 0
137 INT327403 Bcl2 Positive_regulation of Localization of Mmp2 1 0.19 0.93 0
138 INT189673 BCL2 Positive_regulation of Transcription of TERT 1 0.09 0 0
139 INT330056 Bcl2 Regulation of Localization of Cyct 1 0.27 0.97 0
140 INT262515 Positive_regulation of Kcnj6 Positive_regulation of Binding of Bcl2 1 0.00 0.48 0
141 INT201774 Binding of BCL2 and BCL2L1 1 0.00 0.37 0
142 INT292461 PTK2 Regulation of BCL2 1 0.02 0.76 0
143 INT283010 Regulation of Binding of Bcl2 and Becn1 1 0.03 1.45 0
144 INT217141 Binding of BCL2 and MIR15B 1 0.21 1.26 0
145 INT305541 Binding of Bcl2 and Trp53 1 0.05 0.9 0
146 INT282997 Binding of Bcl2 and Om 1 0.00 0.45 0
147 INT193965 Binding of BCL2 and Ps 1 0.05 0.59 0
148 INT296684 Binding of CD99 and Bcl2 1 0.01 1.68 0
149 INT283014 Becn1 Regulation of Bcl2 1 0.03 0.88 0
150 INT104536 Binding of Bcl2 and MIB1 1 0.00 1.61 0
151 INT229816 Fos Regulation of Bcl2 1 0.13 0.31 0
152 INT190681 Binding of Bcl2 and Fkbp1a 1 0.01 0.46 0
153 INT352150 Ift88 Negative_regulation of Bcl2 1 0.00 0.19 0
154 INT327976 PNLIP Negative_regulation of Gene_expression of BCL2 1 0.29 0.53 0
155 INT217146 Binding of BCL2 and MIR16-2 1 0.12 1.25 0
156 INT282998 Binding of Bcl2 and Bbc3 1 0.00 0.43 0
157 INT242479 Negative_regulation of Ciapin1 Negative_regulation of Bcl2 1 0.14 1.28 0
158 INT327974 GOPC Regulation of Gene_expression of BCL2 1 0.13 0.6 0
159 INT201538 Binding of BCL2 and NPC1 1 0.17 1.41 0
160 INT333687 Trp53 Positive_regulation of Localization of Bcl2 1 0.45 1.24 0
161 INT260393 Hmox1 Regulation of Positive_regulation of Bcl2 1 0.22 0.86 0
162 INT254694 Positive_regulation of Map2k2 Regulation of Bcl2 1 0.02 0.89 0
163 INT267254 Binding of Bcl2 and Hspa9 1 0.04 0.54 0
164 INT185853 Binding of BCL2 and BIK 1 0.36 0.59 0
165 INT189993 Binding of Bcl2 and Ptger2 1 0.00 1.43 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for pigment granule organization. They are ordered first by their pain relevance and then by number of times they were reported in pigment granule organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
2 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
3 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
4 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
5 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
6 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
7 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
8 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
9 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
10 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
11 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
12 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
13 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
14 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
15 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
16 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7
17 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22
18 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07
19 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3
20 INT105882 Phosphorylation of Bcl2 11 0.59 8.15 3.73
21 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4
22 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19
23 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16
24 INT105884 Binding of Bcl2 19 0.35 15.67 3
25 INT147349 Localization of Bcl2 13 0.65 7.83 2.31
26 INT142677 Negative_regulation of Positive_regulation of Bcl2 4 0.36 3.09 2.24
27 INT86671 Negative_regulation of Positive_regulation of Bcl2 6 0.57 3.83 2.03
28 INT101108 Localization of Bcl2 16 0.72 11.68 1.86
29 INT105883 Positive_regulation of Phosphorylation of Bcl2 8 0.32 5.67 1.86
30 INT101958 Positive_regulation of Transcription of Bcl2 4 0.50 2.22 1.65
31 INT137513 Negative_regulation of Positive_regulation of BCL2 6 0.35 5.3 1.62
32 INT101107 Positive_regulation of Localization of Bcl2 3 0.48 3.13 1.28
33 INT172855 Binding of Bcl2 37 0.32 23.41 1.09
34 INT70021 Localization of BCL2 23 0.74 21.6 1.09
35 INT151115 Regulation of Regulation of Bcl2 4 0.21 4.12 0.88
36 INT92117 Phosphorylation of BCL2 26 0.80 9.93 0.86
37 INT70019 Binding of BCL2 25 0.47 17.55 0.79
38 INT109404 Transcription of BCL2 6 0.69 4.49 0.77
39 INT124844 Regulation of Positive_regulation of Bcl2 3 0.43 2.55 0.75
40 INT155392 Negative_regulation of Negative_regulation of Bcl2 3 0.21 1.64 0.74
41 INT134444 Positive_regulation of Binding of Bcl2 3 0.47 2.67 0.72
42 INT70025 Positive_regulation of Positive_regulation of BCL2 3 0.27 0.96 0.58
43 INT178128 Negative_regulation of Phosphorylation of BCL2 7 0.27 3.94 0.56
44 INT155090 Regulation of Positive_regulation of BCL2 3 0.26 1.78 0.54
45 INT144696 Regulation of Transcription of Bcl2 5 0.44 2.96 0.51
46 INT134445 Positive_regulation of Positive_regulation of Bcl2 3 0.47 2.43 0.49
47 INT221676 Protein_catabolism of Bcl2 4 0.24 2.77 0.48
48 INT204052 Transcription of Bcl2 5 0.51 3.25 0.45
49 INT140295 Protein_catabolism of BCL2 4 0.64 5.7 0.44
50 INT220424 Positive_regulation of Negative_regulation of Bcl2 2 0.14 1.81 0.44
51 INT155724 Negative_regulation of Transcription of Bcl2 6 0.53 2.35 0.37
52 INT178114 Positive_regulation of Phosphorylation of BCL2 11 0.49 4.44 0.28
53 INT292743 Negative_regulation of Binding of Bcl2 1 0.05 1.97 0.24
54 INT285003 Positive_regulation of Regulation of Bcl2 1 0.46 0.68 0.23
55 INT108563 Negative_regulation of Regulation of Bcl2 1 0.32 0.74 0.22
56 INT220426 Regulation of Negative_regulation of Bcl2 1 0.05 0.81 0.18
57 INT238507 Regulation of Regulation of BCL2 3 0.44 5.14 0.16
58 INT101109 Negative_regulation of Localization of Bcl2 1 0.03 0.62 0.16
59 INT229235 Regulation of Localization of BCL2 2 0.29 3.7 0.15
60 INT102109 Protein_catabolism of Bcl2 1 0.65 0.55 0.15
61 INT110957 Positive_regulation of Positive_regulation of Bcl2 3 0.35 2.3 0.13
62 INT179038 Positive_regulation of Regulation of Bcl2 1 0.39 3.49 0.12
63 INT302229 Negative_regulation of Negative_regulation of BCL2 3 0.21 2.69 0.04
64 INT258045 Positive_regulation of Regulation of BCL2 2 0.36 1.78 0.03
65 INT221673 Negative_regulation of Protein_catabolism of Bcl2 1 0.11 0.15 0.03
66 INT123521 Phosphorylation of Bcl2 8 0.81 5 0
67 INT310419 Negative_regulation of Localization of BCL2 3 0.41 2.51 0
68 INT185909 Regulation of Phosphorylation of BCL2 3 0.24 1.63 0
69 INT155391 Positive_regulation of Negative_regulation of Bcl2 2 0.22 0.92 0
70 INT185887 Regulation of Binding of BCL2 2 0.24 2.22 0
71 INT183619 Negative_regulation of Regulation of BCL2 2 0.33 1.01 0
72 INT191056 Negative_regulation of Binding of Bcl2 2 0.37 0.48 0
73 INT153083 Positive_regulation of Negative_regulation of BCL2 2 0.32 2.9 0
74 INT204053 Negative_regulation of Transcription of Bcl2 1 0.04 0.86 0
75 INT330962 Negative_regulation of Transcription of BCL2 1 0.10 1.21 0
76 INT282976 Positive_regulation of Binding of Bcl2 1 0.29 0.76 0
77 INT191048 Positive_regulation of Phosphorylation of Bcl2 1 0.69 0.44 0
78 INT341935 Regulation of Phosphorylation of Bcl2 1 0.04 0 0
79 INT282971 Positive_regulation of Localization of Bcl2 1 0.29 0 0
80 INT356124 Positive_regulation of Transcription of BCL2 1 0.45 0.3 0
81 INT191049 Regulation of Binding of Bcl2 1 0.39 0.52 0
82 INT184508 Positive_regulation of Localization of BCL2 1 0.07 0.87 0
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