GO:0048771

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Name tissue remodeling
Categary Process
Go Slim No
Go Link GO:0048771
Unique Molecular Interactions 339
Total Molecular Interactions 454
Total Single Events 3603
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for tissue remodeling. They are ordered first by their pain relevance and then by number of times they were reported for tissue remodeling. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT215943 Binding of Mmp14 and Timp2 1 0.21 1.59 3.33
2 INT243043 Binding of Mmp9 and Timp1 1 0.05 0.25 1.86
3 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85
4 INT192161 Mmp14 Positive_regulation of Mmp2 2 0.19 1.23 1.81
5 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75
6 INT158302 Il23a Regulation of Gene_expression of Il17a 1 0.06 1.45 1.7
7 INT168612 Negative_regulation of Nos1 Negative_regulation of Positive_regulation of Mmp9 1 0.23 0.45 1.62
8 INT168607 Negative_regulation of Nos1 Negative_regulation of Mmp9 1 0.23 0.45 1.61
9 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58
10 INT168611 Binding of Mmp9 and Ndor1 1 0.29 0.41 1.57
11 INT168608 Binding of Grin2b and Mmp9 1 0.22 0.41 1.57
12 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33
13 INT202042 CAMK2N2 Negative_regulation of MMP9 1 0.01 0.73 1.25
14 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24
15 INT187172 RPS3AP9 Negative_regulation of MMP9 1 0.00 0.89 1.2
16 INT120313 Gnrhr Negative_regulation of Mmp2 1 0.03 0.85 1.07
17 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
18 INT187111 TIMP2 Regulation of MMP9 1 0.23 1.47 0.97
19 INT266659 Binding of MMP9 and MOCS1 1 0.01 1.71 0.94
20 INT285561 Il23a Positive_regulation of Gene_expression of Il22 2 0.06 2.45 0.93
21 INT243044 Mmp8 Regulation of Mmp9 1 0.05 1.45 0.91
22 INT111924 Cpb2 Negative_regulation of Positive_regulation of Plg 1 0.02 1.29 0.9
23 INT192158 Binding of Mmp2 and Mmp9 1 0.21 0.94 0.83
24 INT153516 PLG Positive_regulation of Pas5a 1 0.57 0.05 0.83
25 INT309001 Ins1 Positive_regulation of Mmp9 1 0.20 1.96 0.83
26 INT196525 Binding of MMP2 and MMP9 2 0.32 2.49 0.78
27 INT102163 Binding of TNF and Mmp9 1 0.12 0.88 0.78
28 INT102161 Binding of TNF and Mmp2 1 0.10 0.88 0.78
29 INT102159 Binding of Adam17 and Mmp2 1 0.18 0.87 0.77
30 INT113472 TNF Positive_regulation of Localization of MMP14 1 0.47 0.45 0.75
31 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 0.06 0.29 0.74
32 INT295720 PTGER2 Regulation of MMP9 1 0.01 0.53 0.7
33 INT224678 Binding of Mmp14 and Mmp23 1 0.00 0.85 0.69
34 INT263049 Positive_regulation of Binding of Mmp2 and Mmp9 1 0.35 0.83 0.69
35 INT152298 Mmp9 Negative_regulation of Tsc22d1 1 0.13 0.16 0.66
36 INT152299 Mmp2 Negative_regulation of Tsc22d1 1 0.16 0.16 0.66
37 INT152296 Regulation of Mmp9 Negative_regulation of Tsc22d1 1 0.08 0.16 0.66
38 INT152297 Mmp2 Negative_regulation of Mmp9 1 0.39 0.16 0.65
39 INT224683 Mmp14 Positive_regulation of Binding of Mmp9 1 0.01 0.81 0.65
40 INT224693 Timp2 Positive_regulation of Binding of Mmp9 1 0.01 0.81 0.65
41 INT224684 Binding of Mmp14 and Mmp9 1 0.01 0.81 0.64
42 INT113473 RETNLB Positive_regulation of MMP14 1 0.01 0.37 0.64
43 INT99728 Binding of F13A1 and PLG 4 0.02 2.51 0.63
44 INT314051 THL Negative_regulation of Localization of Mmp2 1 0.14 1.1 0.62
45 INT302469 F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.82 0.62
46 INT95431 Il1a Regulation of Mmp2 1 0.48 0.25 0.61
47 INT95434 Mmp9 Positive_regulation of Positive_regulation of Il1a 1 0.42 0.23 0.61
48 INT95433 Mmp3 Regulation of Mmp2 1 0.17 0.24 0.6
49 INT295724 CXCL12 Positive_regulation of MMP9 1 0.02 0.32 0.6
50 INT95432 Il1a Positive_regulation of Positive_regulation of Mmp9 1 0.37 0.25 0.6
51 INT95430 Mmp9 Positive_regulation of Mmp3 1 0.38 0.24 0.6
52 INT295721 CSF2 Positive_regulation of MMP9 1 0.06 0.32 0.6
53 INT202038 MMP9 Positive_regulation of IL8 1 0.05 0.29 0.59
54 INT342624 VEGFA Negative_regulation of Mmp2 1 0.09 1.54 0.58
55 INT144071 TRPV1 Positive_regulation of Gene_expression of MMP14 1 0.21 0.5 0.58
56 INT342619 Mmp2 Negative_regulation of Timp2 1 0.42 1.48 0.57
57 INT175626 TIMP1 Positive_regulation of Gene_expression of MMP9 1 0.03 0.72 0.57
58 INT265463 CSPG4 Negative_regulation of Gene_expression of IL6 1 0.06 1.6 0.56
59 INT173556 TIMP1 Negative_regulation of MMP9 1 0.02 0 0.56
60 INT175623 TIMP1 Positive_regulation of MMP9 1 0.03 0.71 0.56
61 INT99736 Binding of PLG and Serpinf2 1 0.01 0.73 0.55
62 INT282711 Binding of Csf2 and Mmp9 1 0.16 1.35 0.54
63 INT314043 THL Negative_regulation of Mmp2 1 0.22 2.11 0.53
64 INT192162 Furin Positive_regulation of Mmp14 1 0.10 0.79 0.53
65 INT192159 Mmp14 Regulation of Protein_catabolism of Col1a1 1 0.02 1.01 0.52
66 INT205728 Mmp9 Positive_regulation of Gene_expression of Mmp3 1 0.29 0 0.52
67 INT282713 Binding of MUC5AC and Mmp9 1 0.02 1.27 0.52
68 INT205727 Mmp3 Positive_regulation of Gene_expression of Mmp9 1 0.29 0 0.52
69 INT196524 Binding of MMP1 and MMP9 1 0.31 0.74 0.51
70 INT196519 Positive_regulation of Binding of MMP1 and MMP9 1 0.42 0.74 0.51
71 INT187116 TIMP2 Negative_regulation of MMP9 1 0.36 1.37 0.5
72 INT150921 ZNF398 Negative_regulation of Gene_expression of Mmp2 1 0.00 0.46 0.5
73 INT230532 LILRB1 Positive_regulation of Gene_expression of Mmp2 1 0.14 1.04 0.5
74 INT230533 LILRB1 Positive_regulation of Positive_regulation of Mmp9 1 0.20 1.03 0.5
75 INT345306 Binding of MMP14 and TIMP2 1 0.04 0.21 0.48
76 INT127664 Negative_regulation of PDE4A Negative_regulation of MMP9 1 0.37 0.76 0.48
77 INT127665 Negative_regulation of PDE4A Negative_regulation of Transcription of MMP9 1 0.37 0.76 0.48
78 INT314053 VEGFA Positive_regulation of Gene_expression of Mmp2 1 0.02 0.2 0.47
79 INT303445 Mmp3 Positive_regulation of Mmp9 1 0.01 1.19 0.47
80 INT149894 Ihh Positive_regulation of Localization of Mmp14 1 0.04 2.06 0.47
81 INT138152 IL6 Positive_regulation of Transcription of Mmp2 1 0.00 0.23 0.46
82 INT138154 IL1B Positive_regulation of Transcription of Mmp2 1 0.04 0.23 0.46
83 INT138149 Tgfb1 Regulation of Mmp2 1 0.00 0.23 0.46
84 INT224674 S100a4 Positive_regulation of Gene_expression of Mmp9 1 0.03 0.85 0.45
85 INT345305 MMP14 Positive_regulation of MMP13 1 0.00 0.33 0.45
86 INT345304 MMP14 Positive_regulation of MMP2 1 0.08 0.2 0.45
87 INT314044 THL Negative_regulation of Transcription of Mmp9 1 0.20 0.81 0.45
88 INT339648 Binding of IL23A and Il23a 1 0.04 0.13 0.44
89 INT314050 THL Negative_regulation of Transcription of Mmp2 1 0.16 0.81 0.44
90 INT113471 RETNLB Regulation of Localization of MMP14 1 0.01 0.24 0.43
91 INT226070 Binding of CRP and MMP9 1 0.51 1.13 0.42
92 INT314042 THL Negative_regulation of Gene_expression of Mmp2 1 0.19 2.97 0.42
93 INT133002 Mmp9 Regulation of Negative_regulation of Igfbp3 1 0.26 0.39 0.42
94 INT181995 TIMP1 Negative_regulation of Mmp9 1 0.01 1.38 0.4
95 INT265465 CSPG4 Negative_regulation of Gene_expression of IL8 1 0.07 0.98 0.39
96 INT314046 THL Negative_regulation of Localization of Mmp9 1 0.13 0.95 0.39
97 INT226072 Binding of MMP9 and SHBG 1 0.15 1.02 0.39
98 INT285560 Il23a Positive_regulation of Il17a 1 0.09 1.45 0.39
99 INT179851 Il11 Positive_regulation of Mmp2 1 0.04 0 0.38
100 INT342622 Binding of MMP14 and Mmp2 1 0.39 1.15 0.37
101 INT342606 Binding of MMP14 and VEGFA 1 0.08 1.16 0.37
102 INT342617 Binding of Col18a1 and Mmp2 1 0.11 1.15 0.37
103 INT302466 Positive_regulation of F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.1 0.35
104 INT113476 IL1A Positive_regulation of Localization of MMP14 1 0.10 0.22 0.34
105 INT149897 Ihh Positive_regulation of Mmp14 1 0.03 0.93 0.33
106 INT326089 Gopc Positive_regulation of Mmp9 1 0.03 0.63 0.33
107 INT295755 Fgf2 Regulation of MMP9 1 0.07 0.99 0.33
108 INT295717 VEGFA Regulation of MMP9 1 0.01 0.98 0.33
109 INT253142 Positive_regulation of Nr1h2 Negative_regulation of Gene_expression of Mmp9 1 0.05 0.6 0.33
110 INT180928 Binding of Col7a1 and Mmp9 1 0.03 0.96 0.32
111 INT340616 COL4A4 Regulation of MMP9 1 0.12 0.95 0.32
112 INT167596 Il23a Positive_regulation of Gene_expression of Ifng 1 0.13 0.94 0.32
113 INT113475 RETNLB Positive_regulation of Localization of MMP14 1 0.01 0.18 0.32
114 INT142286 Binding of PLG and Plat 2 0.52 0.7 0.31
115 INT313915 Binding of Il12a and Il23a 2 0.16 0.44 0.31
116 INT303446 Timp1 Negative_regulation of Mmp2 1 0.19 0.33 0.31
117 INT326090 Binding of Erbb2 and Mmp2 1 0.09 1.39 0.31
118 INT187102 Negative_regulation of Binding of MMP9 and TIMP2 1 0.36 0.69 0.3
119 INT213062 PTGS1 Regulation of Gene_expression of MMP9 1 0.04 0.25 0.3
120 INT187106 Binding of MMP9 and TIMP2 1 0.30 0.69 0.3
121 INT68977 App Positive_regulation of Localization of Mmp9 1 0.05 0.38 0.3
122 INT187113 Binding of IGHG3 and MMP9 1 0.01 0.63 0.3
123 INT260896 CRH Positive_regulation of Localization of MMP9 1 0.15 0.15 0.3
124 INT272932 Binding of Mmp9 and COPD 1 0.01 0.78 0.29
125 INT187105 TIMP2 Negative_regulation of Positive_regulation of MMP9 1 0.36 0.36 0.29
126 INT272929 Positive_regulation of Binding of Mmp9 and COPD 1 0.01 0.79 0.29
127 INT328223 Mmp14 Regulation of Positive_regulation of Mmp13 1 0.07 0.69 0.29
128 INT275548 Il10 Regulation of Mmp9 1 0.00 0.86 0.28
129 INT300548 Napa Positive_regulation of Gene_expression of Il23a 1 0.05 0.86 0.28
130 INT171050 Negative_regulation of F13A1 Regulation of PLG 1 0.02 0.55 0.28
131 INT328222 Mmp2 Regulation of Positive_regulation of Mmp13 1 0.05 0.69 0.28
132 INT171048 F13A1 Regulation of PLG 1 0.02 0.55 0.27
133 INT149898 Ihh Regulation of Localization of Mmp14 1 0.03 1.29 0.27
134 INT76081 Plg Positive_regulation of Gene_expression of IL6 1 0.03 0.18 0.26
135 INT148223 CXCL14 Regulation of Localization of Mmp2 1 0.01 0.71 0.26
136 INT76082 Plg Regulation of Gene_expression of IL6 1 0.01 0.19 0.26
137 INT302468 INCENP Positive_regulation of Gene_expression of MMP9 1 0.01 0.72 0.26
138 INT166664 Mpzl2 Negative_regulation of Mmp9 1 0.31 0.32 0.25
139 INT244687 Mmp14 Positive_regulation of Mmp2 1 0.23 0.48 0.25
140 INT180964 PLG Positive_regulation of MMP13 1 0.24 0.45 0.25
141 INT300546 Binding of Il23a and Il1 1 0.01 0.5 0.25
142 INT166662 Mpzl2 Negative_regulation of Positive_regulation of Mmp9 1 0.31 0.32 0.25
143 INT31097 Binding of Penk and Plg 1 0.29 0.07 0.24
144 INT178077 EDN1 Positive_regulation of MMP9 1 0.06 0.88 0.24
145 INT344797 Gene_expression of Il6 Negative_regulation of Mmp9 1 0.01 0.41 0.24
146 INT205155 Negative_regulation of Binding of CD44 and MMP9 1 0.32 1.98 0.23
147 INT213061 PTGER2 Regulation of Gene_expression of MMP9 1 0.03 0.25 0.23
148 INT216911 Positive_regulation of P2rx7 Positive_regulation of Localization of Plg 1 0.02 0.13 0.23
149 INT309000 Ins1 Positive_regulation of Gene_expression of Mmp9 1 0.20 1.03 0.22
150 INT187117 Negative_regulation of TIMP2 Negative_regulation of MMP9 1 0.36 0.6 0.22
151 INT149900 Gli1 Regulation of Localization of Mmp14 1 0.02 1.17 0.22
152 INT311872 IGHE Positive_regulation of Localization of Mmp9 1 0.01 1.35 0.22
153 INT309002 Ins1 Positive_regulation of Positive_regulation of Mmp9 1 0.20 1.03 0.22
154 INT318994 Il17a Regulation of Il23a 1 0.00 1.38 0.22
155 INT175320 Tlr4 Positive_regulation of Gene_expression of Mmp9 1 0.01 0.54 0.21
156 INT301279 Tnfsf11 Regulation of Gene_expression of Mmp9 1 0.13 0.34 0.21
157 INT215944 Mmp14 Regulation of Eae1 1 0.03 0.95 0.2
158 INT282710 Mmp9 Regulation of Gene_expression of Csf2 1 0.15 0.16 0.2
159 INT215942 Regulation of Mmp14 Regulation of Eae1 1 0.03 0.95 0.2
160 INT255259 Binding of Plg and Tsp1 1 0.05 0.84 0.2
161 INT27675 Plg Positive_regulation of Protein_catabolism of F13A1 1 0.00 0.75 0.2
162 INT325470 MMP3 Positive_regulation of MMP9 1 0.17 0.9 0.2
163 INT99735 Binding of PLG and Ppp1r1a 1 0.00 0.24 0.19
164 INT99727 Binding of SERPINE1 and PLG 1 0.02 0.24 0.19
165 INT335298 IRF6 Positive_regulation of MMP9 1 0.01 0.21 0.19
166 INT237777 Il23a Regulation of Localization of Il12a 1 0.19 0.93 0.19
167 INT46306 Asrgl1 Positive_regulation of Negative_regulation of Plg 1 0.01 1.07 0.19
168 INT226071 Binding of HSD11B1 and MMP9 1 0.09 0.47 0.19
169 INT284450 Edn1 Positive_regulation of Gene_expression of MMP9 1 0.01 0.3 0.18
170 INT259934 Plat Positive_regulation of Gene_expression of Mmp9 2 0.33 1.05 0.17
171 INT259633 Mmp9 Positive_regulation of Gene_expression of COPD 1 0.01 0.92 0.17
172 INT348756 Gopc Positive_regulation of Gene_expression of Mmp9 1 0.10 0.77 0.17
173 INT169117 PLAU Regulation of Gene_expression of MMP9 1 0.47 0.49 0.17
174 INT324899 Edn1 Positive_regulation of Positive_regulation of Mmp9 1 0.10 0.66 0.16
175 INT220531 Atf3 Negative_regulation of Gene_expression of Mmp2 1 0.02 1.09 0.16
176 INT301121 Tgm7 Regulation of Gene_expression of Mmp2 1 0.52 2.53 0.16
177 INT85274 SGCG Positive_regulation of Mmp2 1 0.09 0.46 0.16
178 INT220515 Il10 Negative_regulation of Gene_expression of Mmp2 1 0.01 1.1 0.16
179 INT250908 Binding of Mmp2 and Tsp1 1 0.04 0.09 0.15
180 INT270416 PLAT Negative_regulation of Positive_regulation of PLG 1 0.00 0.48 0.15
181 INT179934 Mapk8 Regulation of Gene_expression of Mmp9 1 0.06 0.48 0.15
182 INT250906 Binding of Mmp2 and Thbs2 1 0.06 0.09 0.15
183 INT222022 Binding of Mmp8 and Mmp9 1 0.28 1.98 0.15
184 INT179931 Ephb1 Regulation of Gene_expression of Mmp9 1 0.04 0.48 0.15
185 INT316535 Il23a Regulation of Il12a 1 0.07 1.15 0.15
186 INT319119 SERPINE1 Negative_regulation of Positive_regulation of PLG 1 0.11 1.56 0.15
187 INT188249 PLAT Positive_regulation of PLG 2 0.10 0.86 0.14
188 INT195443 MMP2 Positive_regulation of Protein_catabolism of Mmp9 1 0.15 0.95 0.14
189 INT314039 THL Negative_regulation of Binding of Mmp2 1 0.16 1.62 0.14
190 INT314041 THL Negative_regulation of Gene_expression of Mmp9 1 0.13 1.86 0.14
191 INT250911 Thbs2 Regulation of Mmp2 1 0.05 0.3 0.13
192 INT174917 Negative_regulation of PLG Negative_regulation of Positive_regulation of FUT1 1 0.01 0.68 0.13
193 INT313913 Binding of Il23a and Il23r 1 0.24 0.43 0.13
194 INT264397 MMP9 Regulation of Positive_regulation of MMP13 1 0.20 0.06 0.12
195 INT264389 MMP14 Regulation of Positive_regulation of MMP13 1 0.31 0.06 0.12
196 INT289253 Il23a Positive_regulation of Stat3 1 0.04 0.37 0.12
197 INT275462 Negative_regulation of JUN Positive_regulation of Gene_expression of MMP9 1 0.04 0.27 0.12
198 INT266660 PTGER2 Positive_regulation of Gene_expression of MMP9 1 0.06 0.08 0.12
199 INT99732 Serpinf2 Negative_regulation of PLG 1 0.01 0.24 0.12
200 INT264395 MMP9 Regulation of Positive_regulation of MMP1 1 0.13 0.06 0.12

Single Events

The table below shows the top 100 pain related interactions that have been reported for tissue remodeling. They are ordered first by their pain relevance and then by number of times they were reported in tissue remodeling. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81
2 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01
3 INT115384 Positive_regulation of Mmp9 121 0.68 94.74 43.02
4 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55
5 INT99610 Localization of MMP9 126 0.79 48.46 32.67
6 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68
7 INT68973 Positive_regulation of Mmp9 89 0.52 58.56 30.04
8 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42
9 INT135411 Gene_expression of Il23a 76 0.72 72.87 26.15
10 INT86295 Gene_expression of Mmp2 114 0.76 73.68 24.25
11 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73
12 INT50814 Positive_regulation of Mmp2 72 0.68 51.37 20.42
13 INT132997 Localization of Mmp9 59 0.80 45.9 17.61
14 INT95767 Negative_regulation of Mmp9 72 0.57 49.14 17.1
15 INT99898 Gene_expression of Mmp14 37 0.56 28.54 16.39
16 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7
17 INT113606 Positive_regulation of Gene_expression of Mmp9 46 0.64 44 15.07
18 INT93715 Negative_regulation of MMP9 69 0.55 36.05 11.73
19 INT68976 Positive_regulation of Gene_expression of Mmp9 34 0.42 28.21 11.28
20 INT86291 Negative_regulation of Mmp2 33 0.57 20.38 10.76
21 INT74681 Positive_regulation of Gene_expression of Mmp2 23 0.55 15.58 10.74
22 INT89282 Regulation of MMP9 39 0.60 25.45 10.34
23 INT113605 Negative_regulation of Gene_expression of Mmp9 25 0.41 22.92 9.98
24 INT126031 Negative_regulation of Gene_expression of MMP9 40 0.57 22.71 9.79
25 INT125247 Negative_regulation of Mmp9 42 0.43 23.68 9.37
26 INT187190 Positive_regulation of Localization of MMP9 27 0.68 8.1 8.93
27 INT111903 Regulation of Mmp2 9 0.61 3.95 7.98
28 INT10145 Gene_expression of Plg 28 0.62 12.68 7.46
29 INT111398 Localization of Mmp2 37 0.76 23.78 7.17
30 INT168600 Binding of Mmp9 14 0.44 12.79 6.92
31 INT16389 Gene_expression of Plg 80 0.67 36.88 6.74
32 INT10610 Negative_regulation of Plg 22 0.40 11.81 6.74
33 INT150023 Positive_regulation of Il23a 25 0.38 18.33 6.32
34 INT4561 Gene_expression of PLG 32 0.75 17.59 6.21
35 INT152293 Regulation of Mmp9 9 0.49 6.57 6.01
36 INT123551 Regulation of Mmp2 17 0.57 11.6 6
37 INT87468 Negative_regulation of Mmp2 24 0.57 10.79 5.55
38 INT99606 Negative_regulation of Localization of MMP9 23 0.57 7.15 5.47
39 INT12104 Positive_regulation of PLG 45 0.68 28.94 4.81
40 INT29502 Localization of Mmp2 18 0.79 3.49 4.64
41 INT160914 Positive_regulation of Positive_regulation of Mmp9 7 0.57 4.69 4.52
42 INT107605 Gene_expression of MMP14 26 0.64 25.88 4.49
43 INT204783 Positive_regulation of Gene_expression of Il23a 17 0.36 15.53 4.42
44 INT113485 Localization of MMP14 11 0.77 3.44 4.19
45 INT125896 Negative_regulation of Gene_expression of Mmp9 15 0.43 13.73 4.18
46 INT99608 Transcription of MMP9 18 0.65 9.67 4.11
47 INT16478 Positive_regulation of Plg 29 0.45 18.07 4.07
48 INT160915 Regulation of Mmp9 16 0.35 10.25 4.07
49 INT17324 Negative_regulation of Plg 26 0.38 13.5 4.05
50 INT133312 Binding of MMP9 25 0.42 16.79 3.83
51 INT86293 Positive_regulation of Gene_expression of Mmp2 21 0.64 11.69 3.79
52 INT132994 Positive_regulation of Localization of Mmp9 12 0.42 9.4 3.75
53 INT16644 Positive_regulation of Plg 16 0.60 6.38 3.62
54 INT161206 Negative_regulation of Localization of Mmp9 10 0.59 9.68 3.59
55 INT68974 Localization of Mmp9 10 0.80 4.84 3.35
56 INT25344 Localization of Plg 10 0.57 5 3.27
57 INT16390 Regulation of Plg 13 0.48 6.72 3.2
58 INT215926 Regulation of Gene_expression of Mmp14 1 0.45 5.33 3.15
59 INT163269 Binding of Il23a 11 0.44 7.2 3.14
60 INT105985 Transcription of Mmp9 11 0.66 8.55 3.02
61 INT138141 Transcription of Mmp2 10 0.64 6.52 2.99
62 INT170305 Regulation of Gene_expression of Mmp9 11 0.33 5.7 2.8
63 INT143952 Regulation of Gene_expression of MMP9 14 0.53 10.16 2.73
64 INT99895 Positive_regulation of Mmp14 10 0.58 6.64 2.72
65 INT99897 Positive_regulation of Gene_expression of Mmp14 7 0.36 6.33 2.51
66 INT103603 Negative_regulation of Gene_expression of Mmp2 16 0.51 12.29 2.47
67 INT183810 Positive_regulation of Positive_regulation of MMP9 9 0.52 4.15 2.46
68 INT168603 Negative_regulation of Positive_regulation of Mmp9 3 0.37 2.32 2.42
69 INT4560 Protein_catabolism of PLG 18 0.96 11.64 2.32
70 INT180923 Negative_regulation of Localization of Mmp2 6 0.46 7.84 2.17
71 INT152286 Regulation of Gene_expression of Mmp9 5 0.36 3.95 2.15
72 INT263046 Negative_regulation of Gene_expression of Mmp2 7 0.34 5.98 2.09
73 INT125246 Negative_regulation of Positive_regulation of Mmp9 5 0.27 5.34 2.09
74 INT17268 Localization of PLG 9 0.78 11.71 2.06
75 INT103244 Protein_catabolism of MMP9 12 0.72 11.81 2.01
76 INT46332 Binding of Mmp2 10 0.34 5.63 2
77 INT35146 Negative_regulation of PLG 27 0.57 17.63 1.98
78 INT215914 Localization of Mmp14 4 0.59 2.26 1.98
79 INT59283 Positive_regulation of Gene_expression of Plg 6 0.25 2.36 1.97
80 INT258780 Regulation of Il23a 6 0.13 4.77 1.96
81 INT17326 Binding of Plg 14 0.43 11.72 1.94
82 INT102158 Protein_catabolism of Mmp9 7 0.65 5.43 1.91
83 INT107607 Negative_regulation of MMP14 10 0.37 6.05 1.83
84 INT152292 Regulation of Gene_expression of Mmp2 6 0.61 3.46 1.76
85 INT168599 Phosphorylation of Mmp9 2 0.71 1.09 1.73
86 INT192152 Negative_regulation of Mmp14 3 0.24 1.69 1.72
87 INT113479 Transcription of MMP14 3 0.51 1.81 1.7
88 INT215921 Regulation of Mmp14 1 0.33 2.8 1.7
89 INT125245 Positive_regulation of Mmp14 4 0.44 4.38 1.67
90 INT168601 Negative_regulation of Phosphorylation of Mmp9 1 0.50 0.45 1.66
91 INT86294 Regulation of Gene_expression of Mmp2 3 0.60 1.12 1.62
92 INT133443 Transcription of Mmp2 8 0.69 2.48 1.61
93 INT186724 Negative_regulation of Transcription of MMP9 5 0.37 1.59 1.57
94 INT176468 Transcription of Mmp14 3 0.52 2.47 1.51
95 INT295688 Positive_regulation of Regulation of MMP9 1 0.14 0.67 1.51
96 INT16388 Protein_catabolism of Plg 6 0.79 3.46 1.4
97 INT86292 Positive_regulation of Positive_regulation of Mmp2 4 0.46 3.09 1.4
98 INT317979 Positive_regulation of Transcription of Mmp2 4 0.46 2.63 1.37
99 INT17325 Negative_regulation of Protein_catabolism of Plg 1 0.32 0 1.37
100 INT237772 Localization of Il23a 5 0.42 4.16 1.34
101 INT105983 Positive_regulation of Transcription of Mmp9 3 0.48 2.82 1.34
102 INT157817 Negative_regulation of Il23a 6 0.39 3.34 1.33
103 INT125897 Binding of Mmp9 3 0.36 2.36 1.32
104 INT238074 Negative_regulation of Positive_regulation of Mmp2 4 0.34 1.79 1.31
105 INT135406 Transcription of Il23a 3 0.32 3.15 1.31
106 INT41381 Positive_regulation of Gene_expression of Plg 8 0.44 3.29 1.3
107 INT18422 Regulation of Plg 6 0.45 1.71 1.22
108 INT187123 Negative_regulation of Positive_regulation of MMP9 7 0.42 2.54 1.17
109 INT86063 Positive_regulation of Positive_regulation of Mmp9 4 0.35 2.34 1.17
110 INT143956 Regulation of Positive_regulation of MMP9 5 0.40 2.61 1.11
111 INT265491 Gene_expression of CSPG4 16 0.58 7.27 1.07
112 INT125248 Negative_regulation of Mmp14 1 0.06 3.06 1.07
113 INT96579 Negative_regulation of Negative_regulation of MMP9 5 0.40 4.55 1.04
114 INT180925 Positive_regulation of Localization of Mmp2 4 0.54 3.21 0.95
115 INT29501 Positive_regulation of Localization of Mmp2 3 0.60 0.42 0.94
116 INT192155 Negative_regulation of Negative_regulation of Mmp14 1 0.17 0.88 0.94
117 INT90370 Gene_expression of Mmp14 3 0.49 3.71 0.93
118 INT187135 Positive_regulation of Negative_regulation of MMP9 3 0.43 1.87 0.92
119 INT29500 Regulation of Localization of Mmp2 3 0.53 0.47 0.92
120 INT258782 Regulation of Regulation of Il23a 1 0.13 0.77 0.92
121 INT97768 Positive_regulation of Gene_expression of PLG 5 0.49 2.49 0.89
122 INT140904 Negative_regulation of Gene_expression of Il23a 3 0.06 2.69 0.86
123 INT35141 Regulation of PLG 6 0.44 2.64 0.85
124 INT160913 Regulation of Positive_regulation of Mmp9 1 0.26 0.86 0.82
125 INT191101 Regulation of Localization of MMP9 6 0.38 2.49 0.81
126 INT187132 Negative_regulation of Binding of MMP9 5 0.36 3.15 0.81
127 INT152290 Regulation of Transcription of Mmp2 1 0.27 0.15 0.8
128 INT256052 Protein_catabolism of Mmp9 3 0.85 2.44 0.79
129 INT30926 Regulation of Gene_expression of Plg 11 0.45 2.14 0.78
130 INT290922 Regulation of Protein_catabolism of Mmp9 2 0.28 0.78 0.75
131 INT123773 Positive_regulation of Positive_regulation of Mmp2 2 0.17 1.83 0.75
132 INT265557 Protein_catabolism of Mmp2 3 0.55 3.15 0.73
133 INT79169 Binding of PLG 10 0.47 5.88 0.72
134 INT144073 Positive_regulation of Gene_expression of MMP14 4 0.24 6.13 0.72
135 INT266797 Negative_regulation of Negative_regulation of Mmp2 1 0.05 0.96 0.7
136 INT13702 Protein_catabolism of Plg 4 0.12 0.88 0.69
137 INT224633 Binding of Mmp14 1 0.06 0.83 0.69
138 INT263047 Transcription of Mmp9 7 0.53 3.61 0.65
139 INT205724 Regulation of Positive_regulation of Mmp9 1 0.32 0.25 0.65
140 INT263044 Negative_regulation of Regulation of Mmp9 1 0.31 0.12 0.65
141 INT204767 Negative_regulation of Transcription of Il23a 2 0.19 2.24 0.62
142 INT149889 Localization of Mmp14 5 0.47 2.58 0.61
143 INT113484 Positive_regulation of Localization of MMP14 1 0.58 0.34 0.6
144 INT196352 Positive_regulation of Transcription of MMP14 1 0.06 0.91 0.58
145 INT283569 Protein_catabolism of Mmp2 5 0.77 3.25 0.56
146 INT215918 Negative_regulation of Positive_regulation of Mmp14 1 0.31 0.45 0.56
147 INT244679 Binding of Mmp2 4 0.30 3.75 0.54
148 INT46340 Positive_regulation of Negative_regulation of Plg 2 0.15 1.71 0.54
149 INT342614 Positive_regulation of Binding of Mmp2 1 0.46 0.6 0.54
150 INT138125 Positive_regulation of MMP14 5 0.49 4.04 0.52
151 INT192153 Protein_catabolism of Mmp14 1 0.31 1.01 0.52
152 INT282919 Regulation of MMP14 1 0.12 1.53 0.52
153 INT58591 Negative_regulation of Positive_regulation of PLG 4 0.42 2.46 0.51
154 INT345323 Protein_catabolism of MMP14 1 0.33 0.12 0.49
155 INT96864 Localization of Plg 7 0.67 2.07 0.48
156 INT151903 Positive_regulation of Positive_regulation of PLG 3 0.45 1.53 0.48
157 INT130732 Binding of MMP14 4 0.36 2.58 0.47
158 INT145144 Positive_regulation of Negative_regulation of Mmp2 1 0.11 0.7 0.46
159 INT17269 Negative_regulation of Localization of PLG 1 0.03 0.54 0.45
160 INT308987 Regulation of Regulation of Mmp9 1 0.17 0.95 0.44
161 INT158577 Negative_regulation of Gene_expression of Plg 7 0.17 3.36 0.43
162 INT244683 Regulation of Positive_regulation of Mmp2 2 0.36 0.78 0.43
163 INT175299 Positive_regulation of Binding of Mmp9 2 0.28 1.17 0.42
164 INT113481 Regulation of Localization of MMP14 1 0.43 0.24 0.42
165 INT204768 Regulation of Gene_expression of Il23a 3 0.11 1.25 0.41
166 INT181988 Negative_regulation of Negative_regulation of Mmp9 1 0.39 1.39 0.41
167 INT39640 Negative_regulation of Gene_expression of Plg 2 0.25 1.13 0.39
168 INT125895 Negative_regulation of Binding of Mmp9 1 0.43 1.15 0.39
169 INT92242 Binding of Plg 2 0.32 1.09 0.37
170 INT269825 Negative_regulation of Transcription of Mmp9 2 0.27 1.61 0.36
171 INT96865 Regulation of Positive_regulation of Plg 1 0.01 0.05 0.36
172 INT257524 Positive_regulation of Negative_regulation of Mmp9 1 0.27 0.15 0.36
173 INT187022 Positive_regulation of Transcription of MMP9 3 0.45 3.27 0.34
174 INT107608 Regulation of Negative_regulation of MMP14 1 0.17 0.4 0.34
175 INT265490 Localization of CSPG4 3 0.20 1.5 0.33
176 INT295690 Negative_regulation of Regulation of MMP9 1 0.11 0.99 0.33
177 INT152276 Regulation of Positive_regulation of PLG 2 0.44 1.53 0.32
178 INT265480 Negative_regulation of CSPG4 5 0.32 2.37 0.31
179 INT68972 Positive_regulation of Localization of Mmp9 1 0.50 0.38 0.3
180 INT85426 Transcription of CSPG4 1 0.23 1.03 0.3
181 INT166099 Phosphorylation of MMP9 2 0.41 0.52 0.29
182 INT204786 Positive_regulation of Transcription of Il23a 1 0.17 1.08 0.29
183 INT586 Positive_regulation of Lipa 2 0.64 1.69 0.28
184 INT216976 Positive_regulation of Positive_regulation of Il23a 3 0.08 0.16 0.27
185 INT180969 Positive_regulation of Protein_catabolism of PLG 1 0.36 0.47 0.27
186 INT29504 Negative_regulation of Localization of Mmp2 1 0.58 0.13 0.26
187 INT212868 Gene_expression of LIPA 4 0.25 0.44 0.25
188 INT148219 Regulation of Localization of Mmp2 1 0.02 0.69 0.25
189 INT200522 Negative_regulation of Negative_regulation of PLG 2 0.41 1.53 0.24
190 INT153877 Positive_regulation of Binding of Plg 1 0.44 0.41 0.23
191 INT38039 Positive_regulation of LIPA 2 0.37 1.36 0.22
192 INT216887 Positive_regulation of Localization of Plg 1 0.04 0.13 0.22
193 INT348918 Negative_regulation of Negative_regulation of CSPG4 1 0.06 0.59 0.2
194 INT220857 Negative_regulation of Transcription of Mmp14 1 0.05 1.04 0.2
195 INT291081 Positive_regulation of Protein_catabolism of Mmp2 1 0.29 0.96 0.2
196 INT291083 Negative_regulation of Protein_catabolism of Mmp2 1 0.24 0.96 0.2
197 INT215917 Regulation of Regulation of Mmp14 1 0.33 0.95 0.2
198 INT291078 Negative_regulation of Protein_catabolism of Mmp9 1 0.26 0.96 0.2
199 INT291079 Positive_regulation of Protein_catabolism of Mmp9 1 0.31 0.96 0.2
200 INT25345 Negative_regulation of Localization of Plg 1 0.08 0.81 0.19
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