GO:0048786

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Name presynaptic active zone
Categary Component
Go Slim No
Go Link GO:0048786
Unique Molecular Interactions 225
Total Molecular Interactions 360
Total Single Events 2895
Pain Genes Associated 23

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for presynaptic active zone. They are ordered first by their pain relevance and then by number of times they were reported for presynaptic active zone. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33
2 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25
3 INT106560 Binding of Ntf3 and Ntrk2 3 0.14 2.47 2.84
4 INT67663 Ins1 Positive_regulation of Ntrk2 1 0.00 0.19 2.59
5 INT106558 Binding of Ntrk2 and Ntrk3 3 0.52 2.51 2.28
6 INT161190 CRX Regulation of Gene_expression of Ntrk2 1 0.04 3.05 2.06
7 INT161187 NMS Regulation of Gene_expression of Ntrk2 1 0.43 3.05 2.06
8 INT145940 Binding of Gad1 and Abat 2 0.14 1.44 1.78
9 INT202912 Uchl1 Positive_regulation of Gene_expression of Ntrk2 1 0.08 1.64 1.42
10 INT107104 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.42 1.86 1.34
11 INT154203 Binding of Pick1 and Grm7 1 0.41 1.64 1.28
12 INT287104 Binding of Ntrk2 and T 1 0.20 3.29 1.26
13 INT352269 Binding of Jund and Adora1 1 0.15 1.2 1.25
14 INT215648 Binding of Adora1 and Gabrd 1 0.03 0.06 1.16
15 INT1619 Binding of Gad1 and Oprl1 1 0.14 0 1.13
16 INT1620 Negative_regulation of Binding of Gad1 and Oprl1 1 0.16 0 1.13
17 INT242624 Binding of Ngf and Ntrk2 5 0.24 0.48 1.11
18 INT60047 Oprl1 Negative_regulation of Phosphorylation of Syn1 1 0.05 0.17 1.05
19 INT258170 Binding of Adora1 and Ppap2a 1 0.05 0.26 0.94
20 INT132610 Bdnf Positive_regulation of Ntrk2 4 0.46 1.09 0.93
21 INT215650 Binding of Adora1 and Drd1a 2 0.39 0.54 0.92
22 INT298289 Runx1 Negative_regulation of Ntrk2 1 0.60 1.09 0.87
23 INT215646 Binding of Adora1 and P2rx2 1 0.13 0.51 0.85
24 INT12137 Ngf Regulation of Gad1 1 0.27 0.67 0.83
25 INT140280 Negative_regulation of Binding of Adora2a and Grina 1 0.21 0.64 0.82
26 INT140281 Binding of Adora2a and Grina 1 0.19 0.64 0.82
27 INT245564 Runx3 Negative_regulation of Ntrk2 3 0.61 1.61 0.79
28 INT60102 Adora1 Regulation of Localization of Calca 1 0.46 0 0.79
29 INT72017 Binding of Adora2a and Ptprg 2 0.07 0 0.77
30 INT110130 NR3C1 Regulation of ADORA1 1 0.04 0.73 0.77
31 INT76498 Binding of Tacr1 and Adora2a 1 0.09 0 0.77
32 INT76499 Binding of Insr and Adora2a 1 0.08 0 0.76
33 INT82040 Adora2a Positive_regulation of Phosphorylation of Ppp1r1b 1 0.11 0 0.75
34 INT82041 Positive_regulation of Adora2a Positive_regulation of Phosphorylation of Ppp1r1b 1 0.12 0 0.72
35 INT195545 Rel Regulation of Gene_expression of Grm3 1 0.01 0.46 0.71
36 INT351375 Mir470 Negative_regulation of Ntrk2 1 0.01 1.54 0.7
37 INT161186 Bdnf Regulation of Gene_expression of Ntrk2 1 0.44 1.05 0.68
38 INT194857 Positive_regulation of Adora2a Positive_regulation of Gene_expression of Vegfa 1 0.23 0.74 0.67
39 INT142244 Positive_regulation of Ntrk2 Positive_regulation of Tcrg-C1 1 0.77 0 0.67
40 INT142243 Ntrk2 Positive_regulation of Tcrg-C1 1 0.77 0 0.67
41 INT161184 NMS Positive_regulation of Gene_expression of Ntrk2 1 0.55 1.3 0.67
42 INT128276 ecs Regulation of Transcription of Slc17a7 1 0.01 0.29 0.65
43 INT313435 Syp Regulation of Th 1 0.43 1.6 0.64
44 INT239501 Binding of Adora2a and Mtx1 1 0.24 0.95 0.64
45 INT128275 Slc17a7 Positive_regulation of Transcription of Slc17a6 1 0.39 0.27 0.63
46 INT215647 Adora1 Positive_regulation of Kcnj5 1 0.00 0 0.62
47 INT90119 Ntrk2 Regulation of Gene_expression of Nfkb1 1 0.01 0.27 0.6
48 INT79740 Ntf3 Regulation of Positive_regulation of Ntrk2 1 0.28 0 0.6
49 INT346412 Binding of Tesc and Sv2a 1 0.02 0.6 0.59
50 INT90115 Ntrk2 Regulation of Jun 1 0.01 0.27 0.57
51 INT298271 Proc Negative_regulation of Gene_expression of Ntrk2 1 0.01 0.79 0.56
52 INT298278 Runx1 Negative_regulation of Gene_expression of Ntrk2 1 0.44 0.8 0.56
53 INT147273 Bdnf Regulation of Syp 1 0.24 0 0.56
54 INT261481 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.02 0.21 0.56
55 INT215644 Binding of Drd2 and Adora2a 1 0.03 0.23 0.55
56 INT311256 Nt5e Positive_regulation of Positive_regulation of Adora1 1 0.49 0.19 0.54
57 INT193554 Ntrk2 Positive_regulation of Positive_regulation of Ephb1 1 0.01 0.73 0.52
58 INT134533 Binding of Ntrk2 and Psds1 1 0.01 0 0.5
59 INT103535 Obfc1 Negative_regulation of Positive_regulation of Gad1 1 0.03 0.07 0.49
60 INT327806 Binding of ADORA1 and ADORA2A 1 0.06 0.18 0.49
61 INT233527 Tlr4 Positive_regulation of ADORA1 1 0.00 0.45 0.47
62 INT128043 Positive_regulation of Ntrk2 Positive_regulation of Phosphorylation of Trib3 1 0.07 0.34 0.45
63 INT154592 Binding of Ntrk2 and Positive_regulation of Gene_expression of Kcna3 1 0.11 0.16 0.44
64 INT165724 Bdkrb1 Positive_regulation of Adora1 1 0.24 1.65 0.43
65 INT12139 Ins1 Regulation of Gad1 1 0.15 0.33 0.42
66 INT89666 Binding of Adora2a and Drd2 1 0.54 0.4 0.42
67 INT215651 Binding of Adora1 and Cpa1 1 0.00 0 0.42
68 INT160971 Gm2111 Positive_regulation of Grm7 1 0.01 0.16 0.41
69 INT55588 Drd2 Regulation of Transcription of Gad1 1 0.15 0.07 0.4
70 INT302871 Negative_regulation of Adora2a Positive_regulation of Phosphorylation of Th 1 0.26 0.12 0.4
71 INT313455 Binding of Ppp2ca and Syp 1 0.45 0.68 0.4
72 INT55589 Drd2 Regulation of Gad1 1 0.15 0.07 0.4
73 INT298296 Gene_expression of Runx1 Negative_regulation of Gene_expression of Ntrk2 1 0.44 0.33 0.39
74 INT79504 Binding of Gad1 and Chat 1 0.35 0 0.38
75 INT264209 Binding of Igh-Lev and Sv2a 1 0.17 1.78 0.38
76 INT201485 Ntrk2 Positive_regulation of Prkcg 1 0.01 0.73 0.38
77 INT148515 Binding of Penk and Slc17a7 1 0.21 0 0.36
78 INT117789 Binding of CALCA and Slc17a7 1 0.09 0 0.35
79 INT239503 Binding of Adora2a and Aes 1 0.24 0.85 0.35
80 INT115162 Adora2a Regulation of Gene_expression of Jun 1 0.49 0.36 0.34
81 INT53127 Binding of Ntrk2 and Ntf4 1 0.12 0 0.33
82 INT115161 Adora2a Regulation of Gene_expression of Cpe 1 0.04 0.36 0.33
83 INT55087 Binding of Gad1 and Penk 1 0.08 0 0.32
84 INT303063 Akt1 Negative_regulation of Gene_expression of Syn1 1 0.09 0.45 0.31
85 INT42253 Bbx Regulation of Gad1 1 0.15 0 0.3
86 INT254122 Adora2a Regulation of Aliq1 1 0.01 0.85 0.3
87 INT215645 Binding of Adora1 and Kcnj5 1 0.00 0.08 0.29
88 INT349951 Grm7 Regulation of pcp 1 0.00 0.56 0.28
89 INT215653 Binding of Adora1 and Adora3 1 0.39 0.07 0.27
90 INT313446 Syp Regulation of Ppp2ca 1 0.58 0.62 0.26
91 INT35021 Ptz1b Regulation of Phosphorylation of Syn1 1 0.01 0 0.26
92 INT88555 Adora2a Negative_regulation of Vegfc 1 0.00 0.17 0.25
93 INT215652 Binding of Adora1 and Npy1r 1 0.39 0.22 0.24
94 INT298297 Pou4f1 Positive_regulation of Gene_expression of Ntrk2 1 0.50 0.36 0.24
95 INT195547 Lct Positive_regulation of Transcription of Grm3 1 0.00 0.06 0.24
96 INT287103 Binding of FL and Ntrk2 1 0.28 0.67 0.24
97 INT183247 ADA Negative_regulation of ADORA1 1 0.01 0 0.23
98 INT298290 Pou4f1 Regulation of Gene_expression of Ntrk2 1 0.29 0.48 0.23
99 INT356231 Binding of Gabrb3 and Gad1 1 0.32 1.25 0.23
100 INT293505 Binding of Cnr1 and Slc17a7 1 0.11 0 0.23
101 INT195548 Lct Positive_regulation of Grm3 1 0.00 0.06 0.23
102 INT305509 Slc17a7 Positive_regulation of Ex 1 0.05 0.09 0.23
103 INT224130 Positive_regulation of Adora2a Positive_regulation of ADCY1 1 0.01 0.11 0.22
104 INT224087 Adrbk1 Negative_regulation of Adora2a 1 0.10 0.13 0.22
105 INT180247 Binding of Gad1 and Tbca 1 0.02 0.22 0.22
106 INT35023 Ptz1b Positive_regulation of Phosphorylation of Syn1 1 0.01 0 0.22
107 INT154591 Binding of Ntrk2 and Positive_regulation of Kcna3 1 0.11 0.08 0.22
108 INT180248 Binding of Gad1 and Plp1 1 0.08 0.22 0.21
109 INT72015 Binding of Adora2a and Gnai2 1 0.01 0 0.21
110 INT308650 Binding of nt and Ntrk2 1 0.01 0.41 0.21
111 INT316945 Positive_regulation of Ltp Positive_regulation of Positive_regulation of Syp 1 0.01 0 0.21
112 INT298275 Binding of Runx3 and Ntrk2 1 0.37 0.16 0.21
113 INT47694 sps Regulation of Ntrk2 1 0.00 0.98 0.2
114 INT287100 FL Positive_regulation of Ntrk2 1 0.30 0.61 0.2
115 INT298294 Gene_expression of Runx3 Negative_regulation of Ntrk2 1 0.39 0.16 0.19
116 INT154593 Ntrk2 Regulation of Kcna3 1 0.06 0.06 0.19
117 INT316946 Ltp Positive_regulation of Positive_regulation of Syp 1 0.01 0 0.19
118 INT287097 T Positive_regulation of Ntrk2 1 0.21 0.6 0.19
119 INT280485 Ntrk2 Positive_regulation of Localization of Bdnf 1 0.55 0.45 0.19
120 INT338443 Binding of Gad1 and Slc32a1 1 0.31 0.64 0.18
121 INT280486 Binding of Ngfr and Ntrk2 2 0.18 1.21 0.17
122 INT224094 Adrbk1 Regulation of Negative_regulation of Adora2a 1 0.06 0 0.17
123 INT320259 Binding of Ntrk2 and Atf3 1 0.01 0.38 0.17
124 INT320263 Binding of Ntrk2 and Atf4 1 0.01 0.38 0.17
125 INT298265 Runx3 Negative_regulation of Gene_expression of Ntrk2 1 0.61 0.25 0.17
126 INT298293 Runx1 Positive_regulation of Negative_regulation of Ntrk2 1 0.52 0.54 0.16
127 INT241967 Binding of Grm7 and Acpt 1 0.17 0 0.16
128 INT300861 Ngf Positive_regulation of Ntrk2 1 0.29 0.27 0.15
129 INT223475 Binding of Ntrk1 and Ntrk2 2 0.22 0.25 0.14
130 INT321181 Binding of Ntrk2 and Ntf5 1 0.09 0.08 0.14
131 INT249322 Positive_regulation of Adora1 Regulation of Rit2 1 0.10 0 0.14
132 INT224129 Binding of DRD2 and Adora2a 1 0.03 0.19 0.14
133 INT180252 Negative_regulation of Gad1 Positive_regulation of CP 1 0.03 0.75 0.14
134 INT320261 Binding of Myc and Ntrk2 1 0.01 0.36 0.13
135 INT313439 Syp Negative_regulation of Th 1 0.30 0.14 0.13
136 INT313466 Syp Negative_regulation of Siglec1 1 0.05 0.24 0.12
137 INT249321 Positive_regulation of Adora1 Regulation of Preb 1 0.20 0.09 0.12
138 INT349858 Binding of Ngfr and Ntrk2 1 0.09 0.32 0.11
139 INT177490 Binding of Gad1 and Gad2 1 0.10 0.19 0.11
140 INT342405 AAVS1 Positive_regulation of Syp 1 0.05 0.19 0.11
141 INT313454 Negative_regulation of Syp Negative_regulation of Th 1 0.30 0.14 0.1
142 INT346526 Binding of ADORA1 and PTH1R 1 0.01 0 0.1
143 INT303081 Binding of Mafk and Syn1 1 0.07 0.37 0.1
144 INT313430 Syp Positive_regulation of Ppp2ca 1 0.66 0.08 0.09
145 INT262335 Binding of Sv2a and Bri3 1 0.01 0.71 0.08
146 INT313442 Th Regulation of Phosphorylation of Syp 1 0.32 0 0.08
147 INT251231 Binding of Syp and Slc17a6 1 0.04 0 0.08
148 INT313447 Ppp2ca Regulation of Phosphorylation of Syp 1 0.43 0 0.08
149 INT322969 Binding of Gad1 and Fos 1 0.23 0.23 0.08
150 INT313459 Gene_expression of Syp Negative_regulation of Th 1 0.30 0.49 0.08
151 INT340318 Gopc Regulation of Ntrk2 1 0.24 0.1 0.08
152 INT342404 Binding of AAVS1 and Syp 1 0.04 0.07 0.08
153 INT283352 Binding of Srr and Bsn 1 0.14 0 0.08
154 INT300869 Ntrk2 Positive_regulation of Gene_expression of Ngf 1 0.21 0.16 0.08
155 INT277431 Positive_regulation of Grm3 Positive_regulation of Gene_expression of Gdnf 1 0.18 0 0.07
156 INT261395 Nsdhl Positive_regulation of Syn1 1 0.00 0.59 0.07
157 INT261392 Binding of Nsdhl and Syn1 1 0.00 0.65 0.07
158 INT215188 Binding of Ntrk2 and Nnat 1 0.00 0.15 0.07
159 INT303061 Akt1 Negative_regulation of Syn1 1 0.06 0 0.07
160 INT346415 Binding of Mns1 and Sv2a 1 0.03 0.14 0.07
161 INT195556 Smc2 Regulation of Gene_expression of Grm3 1 0.01 0 0.06
162 INT313450 Th Regulation of Syp 1 0.32 0.6 0.06
163 INT313463 Ppp2ca Regulation of Syp 1 0.43 0.6 0.06
164 INT303057 Binding of Syn1 and Syt1 1 0.07 0.19 0.05
165 INT303060 Akt1 Regulation of Gene_expression of Syn1 1 0.04 0 0.05
166 INT270705 Negative_regulation of Bdnf Positive_regulation of Ntrk2 1 0.22 0 0.05
167 INT257878 Ins1 Positive_regulation of Gene_expression of Ntrk2 1 0.00 0.65 0.04
168 INT303064 Negative_regulation of Akt1 Positive_regulation of Gene_expression of Syn1 1 0.07 0.25 0.04
169 INT236596 Ncoa2 Positive_regulation of PELP1 1 0.36 0.17 0.04
170 INT307462 Gsk3a Regulation of Ntrk2 1 0.04 0.09 0.04
171 INT257877 Ins1 Positive_regulation of Phosphorylation of Ntrk2 1 0.00 0.66 0.04
172 INT342403 Regulation of Binding of AAVS1 and Syp 1 0.04 0 0.04
173 INT307456 Bdnf Positive_regulation of Transcription of Ntrk2 1 0.14 0.25 0.04
174 INT307461 Bdnf Positive_regulation of Ntrk2 1 0.19 0.25 0.04
175 INT346418 Sv2a Positive_regulation of Binding of Tesc 1 0.02 0.1 0.04
176 INT283344 Regulation of Binding of Srr and Bsn 1 0.08 0 0.04
177 INT313462 Syp Positive_regulation of Binding of Ppp2ca 1 0.47 0 0.04
178 INT346407 Negative_regulation of Binding of Tesc and Sv2a 1 0.02 0 0.03
179 INT236586 Binding of Ncoa2 and Psmd4 1 0.12 0.22 0.03
180 INT236590 Binding of Adipoq and Ncoa2 1 0.15 0.2 0.03
181 INT321178 Binding of Ntrk2 and Mgst1 1 0.07 0 0.03
182 INT238086 Binding of C2 and Syp 1 0.00 0 0.03
183 INT85473 Ntrk2 Regulation of Gene_expression of Pdyn 1 0.01 0.38 0.03
184 INT313448 Gene_expression of Syp Positive_regulation of Th 1 0.28 0 0.03
185 INT313468 Negative_regulation of Syp Regulation of Th 1 0.30 0.3 0.03
186 INT195543 Smc2 Regulation of Transcription of Grm3 1 0.01 0 0.03
187 INT243110 Pprc1 Negative_regulation of Ncoa2 1 0.00 0.52 0.03
188 INT236592 Positive_regulation of Binding of Adipoq and Ncoa2 1 0.19 0.2 0.03
189 INT236585 Ncoa2 Positive_regulation of Transcription of Ncoa1 1 0.27 0.23 0.03
190 INT313451 Gene_expression of Syp Negative_regulation of Mapk1 1 0.09 0 0.03
191 INT314397 Binding of Ptpn6 and Slc17a7 1 0.05 0 0
192 INT313443 Syp Positive_regulation of Binding of Th 1 0.35 0.31 0
193 INT177254 Binding of CXADR and NCOA2 1 0.19 0 0
194 INT307458 Ntrk2 Positive_regulation of Phosphorylation of Gsk3a 1 0.05 0 0
195 INT225520 Binding of Ncoa2 and Ncoa6 1 0.05 0.11 0
196 INT321180 Ntrk2 Regulation of Ntrk1 1 0.16 0 0
197 INT321179 Negative_regulation of Binding of Bdnf and Ntrk2 1 0.38 0 0
198 INT313429 Syp Regulation of Phosphorylation of Siglec1 1 0.04 0.57 0
199 INT235697 Binding of Clcn1 and Syn1 1 0.00 0.48 0
200 INT283342 Binding of Bsn and Erc1 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for presynaptic active zone. They are ordered first by their pain relevance and then by number of times they were reported in presynaptic active zone. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT26788 Gene_expression of Gad1 93 0.78 27.05 42.71
2 INT27798 Gene_expression of Ntrk2 111 0.78 56.08 42.68
3 INT102902 Gene_expression of Ntrk2 152 0.78 81.52 39.43
4 INT40160 Positive_regulation of Adora1 74 0.70 26.36 33.03
5 INT10453 Positive_regulation of Gad1 65 0.70 10.75 31.9
6 INT1616 Regulation of Gad1 46 0.61 10.2 28.64
7 INT16326 Transcription of Gad1 58 0.71 15.78 20.45
8 INT47689 Positive_regulation of Ntrk2 44 0.68 16.84 19.59
9 INT107930 Gene_expression of Slc17a7 39 0.78 6.53 18.86
10 INT66039 Positive_regulation of Ntrk2 53 0.69 15.87 17.23
11 INT62564 Gene_expression of Syp 40 0.76 15.56 17
12 INT22143 Gene_expression of Gad1 35 0.76 14.4 15.4
13 INT25872 Positive_regulation of Adora1 19 0.69 4.9 15.01
14 INT60044 Gene_expression of Syn1 38 0.78 4.98 14.61
15 INT15042 Gene_expression of Adora2a 37 0.77 3.77 14.24
16 INT60046 Positive_regulation of Syn1 16 0.70 2 13.9
17 INT108063 Gene_expression of Adora2a 29 0.78 13.11 13.78
18 INT65172 Negative_regulation of Ntrk2 35 0.59 9.89 13.08
19 INT50227 Positive_regulation of Adora2a 32 0.50 5.17 12.75
20 INT72784 Positive_regulation of Adora2a 26 0.70 16.52 11.47
21 INT19155 Binding of Adora1 25 0.47 6.41 10.72
22 INT106477 Positive_regulation of Syp 21 0.68 8.69 10.3
23 INT336 Negative_regulation of Gad1 19 0.58 7.71 9.51
24 INT114406 Gene_expression of Adora1 28 0.72 6.83 9.13
25 INT26789 Positive_regulation of Gene_expression of Gad1 22 0.70 7.39 9.02
26 INT6499 Localization of Ntrk2 44 0.79 11.78 8.75
27 INT47682 Transcription of Ntrk2 19 0.69 6.32 8.6
28 INT23209 Binding of Adora2a 17 0.38 2.04 8.35
29 INT139930 Gene_expression of Slc17a7 35 0.75 6.22 8.33
30 INT73544 Gene_expression of Grm7 34 0.64 31.28 8.04
31 INT9350 Regulation of ADORA1 9 0.12 1.53 7.79
32 INT54755 Negative_regulation of Adora2a 17 0.58 2.7 7.75
33 INT101699 Regulation of Adora1 14 0.61 3.7 7.59
34 INT40159 Negative_regulation of Adora1 13 0.51 3.51 7.13
35 INT76197 Positive_regulation of ADORA1 7 0.59 5.06 7
36 INT47691 Positive_regulation of Gene_expression of Ntrk2 17 0.62 13.64 6.96
37 INT9167 Binding of Adora1 6 0.40 0.53 6.9
38 INT76255 Gene_expression of ADORA1 11 0.78 2.51 6.85
39 INT47681 Regulation of Ntrk2 17 0.62 3.61 6.31
40 INT115677 Positive_regulation of Gene_expression of Syp 15 0.63 4.69 6.25
41 INT49011 Regulation of Gene_expression of Gad1 10 0.62 0.55 6.07
42 INT63728 Transcription of Syn1 6 0.72 0.38 6.07
43 INT63726 Positive_regulation of Transcription of Syn1 1 0.70 0.39 5.99
44 INT106552 Positive_regulation of Gene_expression of Ntrk2 19 0.68 9.72 5.51
45 INT83014 Binding of Adora2a 13 0.48 5.57 5.33
46 INT160853 Gene_expression of Syp 87 0.72 20.06 5.31
47 INT107103 Negative_regulation of Ntrk2 21 0.59 10.38 5.28
48 INT89664 Negative_regulation of Adora2a 11 0.59 7.81 5.07
49 INT106555 Binding of Ntrk2 15 0.48 6.31 5.05
50 INT51468 Regulation of Adora2a 8 0.48 1.5 4.84
51 INT66388 Positive_regulation of Transcription of Gad1 14 0.67 2.45 4.67
52 INT79682 Gene_expression of Grm7 6 0.75 4.74 4.5
53 INT65056 Binding of Ntrk2 20 0.36 3.72 4.42
54 INT122882 Regulation of Ntrk2 13 0.62 9.7 4.3
55 INT35019 Phosphorylation of Syn1 11 0.82 0.33 4.28
56 INT47686 Regulation of Gene_expression of Ntrk2 5 0.44 5.24 4.14
57 INT195522 Gene_expression of Grm3 12 0.24 2.32 4.13
58 INT50228 Positive_regulation of Positive_regulation of Adora2a 8 0.39 0.1 4
59 INT200047 Negative_regulation of Gene_expression of Ntrk2 8 0.56 10.78 3.95
60 INT65527 Positive_regulation of Positive_regulation of Adora1 4 0.46 0.67 3.71
61 INT134527 Phosphorylation of Ntrk2 7 0.69 3.72 3.65
62 INT101701 Regulation of Adora2a 8 0.45 2.3 3.63
63 INT79680 Binding of Grm7 6 0.47 2.83 3.58
64 INT215604 Localization of Adora1 10 0.78 1.47 3.49
65 INT42251 Regulation of Gad1 10 0.44 5.25 3.45
66 INT63727 Positive_regulation of Gene_expression of Syn1 4 0.50 2.1 3.31
67 INT35017 Negative_regulation of Phosphorylation of Syn1 5 0.59 0.24 3.22
68 INT115407 Transcription of Slc17a7 2 0.72 1.28 3.12
69 INT101477 Binding of ADORA1 8 0.31 0.42 3.07
70 INT67952 Regulation of Transcription of Gad1 6 0.51 1.23 2.98
71 INT54170 Positive_regulation of Positive_regulation of Gad1 5 0.69 0 2.89
72 INT54178 Regulation of Adora1 5 0.39 0.29 2.85
73 INT61311 Negative_regulation of Gene_expression of Syn1 4 0.59 0.48 2.85
74 INT121759 Localization of Syp 8 0.73 1.78 2.84
75 INT142237 Phosphorylation of Ntrk2 8 0.82 2.24 2.82
76 INT128268 Positive_regulation of Gene_expression of Slc17a7 4 0.70 1.34 2.78
77 INT215608 Negative_regulation of Binding of Adora1 5 0.41 1.35 2.73
78 INT280459 Regulation of Gene_expression of Ntrk2 13 0.62 8.48 2.71
79 INT163206 Transcription of Grm3 2 0.45 2.03 2.68
80 INT215601 Regulation of Positive_regulation of Adora1 9 0.60 1.74 2.66
81 INT215599 Positive_regulation of Positive_regulation of Adora1 7 0.47 2.29 2.58
82 INT114020 Gene_expression of Adora1 2 0.33 4.24 2.55
83 INT42255 Negative_regulation of Gad1 7 0.56 4.83 2.54
84 INT67621 Negative_regulation of Gene_expression of Ntrk2 7 0.41 2.71 2.52
85 INT129695 Binding of Sv2a 6 0.47 4.96 2.51
86 INT254118 Negative_regulation of Gene_expression of Adora2a 3 0.42 2.54 2.43
87 INT90566 Positive_regulation of Gene_expression of Gad1 5 0.48 1.46 2.42
88 INT183167 Positive_regulation of Gene_expression of Adora2a 4 0.70 2.37 2.31
89 INT156373 Binding of Sv2a 4 0.39 1.54 2.3
90 INT106476 Regulation of Gene_expression of Syp 3 0.60 2.32 2.3
91 INT47687 Positive_regulation of Transcription of Ntrk2 5 0.45 2.42 2.24
92 INT264600 Negative_regulation of Gene_expression of Syp 8 0.31 2.88 2.23
93 INT107102 Negative_regulation of Positive_regulation of Ntrk2 6 0.54 1.61 2.21
94 INT215611 Negative_regulation of Positive_regulation of Adora1 6 0.43 1.18 2.16
95 INT195525 Regulation of Gene_expression of Grm3 1 0.04 0.82 2.14
96 INT67951 Negative_regulation of Gene_expression of Gad1 4 0.43 1.08 2.13
97 INT129505 Regulation of Slc17a7 5 0.37 1.09 2.11
98 INT42256 Positive_regulation of Gad1 4 0.66 1.1 2.09
99 INT57939 Negative_regulation of Gene_expression of Adora2a 4 0.36 0.15 2.02
100 INT44109 Localization of Gad1 7 0.74 1.06 1.97
101 INT110242 Regulation of Syp 4 0.32 1.72 1.96
102 INT72785 Positive_regulation of Positive_regulation of Adora2a 2 0.10 1.34 1.96
103 INT128267 Positive_regulation of Transcription of Slc17a7 1 0.70 0.82 1.9
104 INT194847 Negative_regulation of Positive_regulation of Adora2a 3 0.32 4.52 1.88
105 INT245663 Phosphorylation of Syp 2 0.76 7.4 1.88
106 INT32558 Negative_regulation of ADORA1 5 0.12 2.77 1.86
107 INT55587 Negative_regulation of Positive_regulation of Gad1 6 0.49 1.1 1.82
108 INT128269 Positive_regulation of Slc17a7 3 0.50 1.06 1.82
109 INT115674 Negative_regulation of Syn1 3 0.41 1.22 1.81
110 INT124556 Negative_regulation of Positive_regulation of Adora1 3 0.51 1.2 1.81
111 INT122435 Positive_regulation of Grm7 3 0.00 1.89 1.79
112 INT168519 Positive_regulation of Gene_expression of Adora1 4 0.61 0.75 1.75
113 INT79683 Negative_regulation of Grm7 3 0.41 2.22 1.75
114 INT100135 Negative_regulation of Syp 6 0.57 2.76 1.74
115 INT128273 Regulation of Gene_expression of Slc17a7 3 0.62 0.82 1.72
116 INT195535 Positive_regulation of Grm3 8 0.25 3.37 1.67
117 INT24238 Phosphorylation of Syn1 11 0.45 2.97 1.65
118 INT29763 Negative_regulation of Adora1 3 0.42 0 1.64
119 INT346404 Gene_expression of Sv2a 1 0.72 3.2 1.62
120 INT76496 Localization of Adora2a 3 0.48 0.3 1.54
121 INT326192 Negative_regulation of Binding of Ntrk2 1 0.10 1 1.47
122 INT62015 Gene_expression of Sv2a 3 0.30 0.99 1.45
123 INT142241 Positive_regulation of Positive_regulation of Ntrk2 3 0.66 0.87 1.43
124 INT103531 Regulation of Positive_regulation of Gad1 3 0.61 0.31 1.43
125 INT195526 Positive_regulation of Transcription of Grm3 1 0.04 1.12 1.43
126 INT241721 Positive_regulation of Transcription of Adora1 3 0.50 1.39 1.41
127 INT90567 Negative_regulation of Gene_expression of Gad1 4 0.41 2.88 1.36
128 INT96641 Transcription of Gad1 3 0.60 0.84 1.36
129 INT79681 Localization of Grm7 5 0.78 2.57 1.34
130 INT60043 Regulation of Syn1 2 0.27 0.33 1.33
131 INT245544 Localization of Ntrk2 7 0.77 4.52 1.32
132 INT53548 Negative_regulation of Transcription of Gad1 3 0.43 0.46 1.32
133 INT241737 Transcription of Adora1 3 0.72 0.89 1.32
134 INT1618 Binding of Gad1 6 0.37 2.01 1.3
135 INT245670 Positive_regulation of Gene_expression of Syp 37 0.65 7.34 1.25
136 INT227150 Localization of Gad1 4 0.49 0.15 1.22
137 INT130323 Regulation of Grm7 3 0.26 1.9 1.21
138 INT255271 Positive_regulation of Gene_expression of Slc17a7 3 0.59 1.48 1.19
139 INT91595 Regulation of Gene_expression of Adora2a 1 0.52 0 1.19
140 INT63729 Regulation of Gene_expression of Syn1 2 0.62 0.43 1.14
141 INT76254 Positive_regulation of Positive_regulation of ADORA1 2 0.43 1.27 1.14
142 INT305488 Binding of Slc17a7 2 0.32 2.61 1.13
143 INT165513 Negative_regulation of Regulation of Gad1 1 0.41 1.59 1.11
144 INT11934 Regulation of Sv2a 4 0.44 1.72 1.1
145 INT354246 Negative_regulation of Slc17a7 1 0.40 0.28 1.09
146 INT136284 Binding of Syp 3 0.36 0.73 1.08
147 INT266292 Localization of Slc17a7 3 0.51 0.73 0.98
148 INT52090 Transcription of Adora2a 3 0.41 0.33 0.96
149 INT214113 Transcription of Ntrk2 2 0.72 1.84 0.96
150 INT138941 Regulation of Transcription of Ntrk2 2 0.47 0.76 0.95
151 INT72006 Positive_regulation of Negative_regulation of Adora2a 2 0.40 0.26 0.94
152 INT158378 Transcription of Grm7 1 0.00 0.65 0.94
153 INT185969 Regulation of Syp 5 0.57 2.58 0.92
154 INT90568 Regulation of Gene_expression of Gad1 3 0.27 0.46 0.89
155 INT185973 Negative_regulation of Syp 16 0.54 2.83 0.87
156 INT215606 Positive_regulation of Localization of Adora1 3 0.49 0.44 0.87
157 INT180240 Binding of Gad1 7 0.47 2.99 0.86
158 INT287686 Positive_regulation of Positive_regulation of Syp 2 0.36 1.08 0.86
159 INT228443 Regulation of Positive_regulation of Ntrk2 3 0.22 0.81 0.84
160 INT92880 Localization of ADORA1 2 0.80 0.09 0.84
161 INT302869 Phosphorylation of Adora2a 1 0.49 0.25 0.78
162 INT302868 Positive_regulation of Phosphorylation of Adora2a 1 0.41 0.25 0.78
163 INT80147 Negative_regulation of Binding of Adora2a 2 0.43 0.15 0.77
164 INT107101 Positive_regulation of Negative_regulation of Ntrk2 1 0.46 0.56 0.77
165 INT228439 Positive_regulation of Regulation of Ntrk2 1 0.01 0.28 0.76
166 INT316932 Regulation of Positive_regulation of Syp 1 0.33 0.72 0.76
167 INT89663 Localization of Adora2a 1 0.74 0.74 0.75
168 INT194852 Protein_catabolism of Adora2a 1 0.56 0.6 0.75
169 INT142239 Regulation of Phosphorylation of Ntrk2 1 0.45 0 0.74
170 INT113512 Regulation of Gene_expression of ADORA1 1 0.11 0.19 0.73
171 INT234494 Positive_regulation of Syp 12 0.65 2.47 0.69
172 INT91056 Negative_regulation of Gene_expression of Grm7 2 0.18 1.21 0.69
173 INT224109 Phosphorylation of Adora2a 1 0.52 0.07 0.69
174 INT255276 Positive_regulation of Slc17a7 5 0.59 1.88 0.68
175 INT345211 Positive_regulation of Grm7 1 0.02 0.64 0.66
176 INT54183 Regulation of Positive_regulation of Adora1 1 0.17 0 0.65
177 INT128271 Regulation of Transcription of Slc17a7 1 0.45 0.29 0.64
178 INT215607 Positive_regulation of Negative_regulation of Adora1 1 0.45 0 0.63
179 INT154199 Regulation of Localization of Grm7 1 0.60 0.92 0.62
180 INT346381 Localization of Sv2a 1 0.69 1.12 0.61
181 INT215637 Regulation of Regulation of Adora2a 1 0.14 0.16 0.61
182 INT346389 Negative_regulation of Sv2a 1 0.47 0.41 0.61
183 INT261850 Regulation of Positive_regulation of Slc17a7 1 0.10 0.49 0.58
184 INT141458 Regulation of Gene_expression of Adora2a 2 0.45 0.67 0.57
185 INT120995 Positive_regulation of Gene_expression of Grm7 1 0.00 0.57 0.57
186 INT251227 Binding of Syp 2 0.45 2.42 0.55
187 INT100136 Negative_regulation of Negative_regulation of Syp 1 0.42 0.62 0.55
188 INT215639 Positive_regulation of Binding of Adora2a 1 0.24 0.24 0.55
189 INT216748 Regulation of Localization of ADORA1 1 0.07 0.09 0.53
190 INT150459 Positive_regulation of Phosphorylation of Ntrk2 2 0.42 0.24 0.52
191 INT123645 Negative_regulation of Transcription of Gad1 2 0.42 0.76 0.52
192 INT35018 Regulation of Phosphorylation of Syn1 1 0.44 0 0.52
193 INT224106 Regulation of Negative_regulation of Adora2a 1 0.17 0.26 0.51
194 INT279525 Negative_regulation of Transcription of Adora1 1 0.43 0.26 0.51
195 INT231296 Gene_expression of Syn1 8 0.23 0.65 0.49
196 INT249309 Regulation of Gene_expression of Adora1 6 0.39 0.51 0.49
197 INT69892 Regulation of Regulation of Ntrk2 1 0.62 0.14 0.49
198 INT215600 Regulation of Binding of Adora1 1 0.08 0.09 0.48
199 INT224107 Negative_regulation of Negative_regulation of Adora2a 1 0.28 0.32 0.48
200 INT47688 Negative_regulation of Positive_regulation of Ntrk2 2 0.41 1.79 0.47
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