GO:0048787

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Name presynaptic active zone membrane
Categary Component
Go Slim No
Go Link GO:0048787
Unique Molecular Interactions 26
Total Molecular Interactions 56
Total Single Events 288
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for presynaptic active zone membrane. They are ordered first by their pain relevance and then by number of times they were reported for presynaptic active zone membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT154203 Binding of Pick1 and Grm7 1 0.41 1.64 1.28
2 INT64077 Trpv1 Positive_regulation of Kcnma1 1 0.00 0.37 1.27
3 INT320021 Prkaca Regulation of Positive_regulation of Kcnma1 1 0.00 0.54 1
4 INT128602 Binding of Kcnma1 and Gtf2ird2 1 0.00 0 0.97
5 INT112642 Positive_regulation of Kcnma1 Positive_regulation of Nav1 1 0.02 0 0.89
6 INT160971 Gm2111 Positive_regulation of Grm7 1 0.01 0.16 0.41
7 INT349951 Grm7 Regulation of pcp 1 0.00 0.56 0.28
8 INT165478 Prok2 Positive_regulation of Positive_regulation of Kcnma1 1 0.02 0 0.25
9 INT288582 Binding of Cav1 and Kcnma1 1 0.11 0 0.22
10 INT216487 Ca2 Negative_regulation of Kcnma1 1 0.00 0.1 0.17
11 INT208983 Binding of Ca2 and Kcnma1 2 0.01 0.28 0.1
12 INT216570 Gene_expression of cx Positive_regulation of Kcnma1 1 0.00 0.25 0.06
13 INT216545 Gene_expression of Cftr Negative_regulation of Kcnma1 1 0.00 0.59 0.06
14 INT288595 Binding of CYTIP and Kcnma1 1 0.00 0 0.04
15 INT323286 CYP4A11 Positive_regulation of Kcnma1 1 0.01 0.45 0.04
16 INT100747 Kcnma1 Positive_regulation of sar 1 0.03 0 0
17 INT288584 Cav1 Regulation of Gene_expression of Kcnma1 1 0.14 0 0
18 INT288594 Regulation of Binding of CAV1 and Kcnma1 1 0.01 0 0
19 INT288587 Cav1 Regulation of Binding of Kcnma1 1 0.14 0 0
20 INT288597 Binding of CAV1 and Kcnma1 1 0.01 0.17 0
21 INT288596 Positive_regulation of Binding of CAV1 and Kcnma1 1 0.01 0.1 0
22 INT288593 Cav1 Positive_regulation of Binding of Kcnma1 1 0.15 0 0
23 INT288591 Cav1 Positive_regulation of Kcnma1 1 0.15 0 0
24 INT288586 Cav1 Positive_regulation of Regulation of Kcnma1 1 0.21 0 0
25 INT288583 Negative_regulation of Binding of Cav1 and Kcnma1 1 0.13 0 0
26 INT288589 Cav1 Regulation of Kcnma1 1 0.19 0.05 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for presynaptic active zone membrane. They are ordered first by their pain relevance and then by number of times they were reported in presynaptic active zone membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT72252 Gene_expression of Kcnma1 63 0.64 20.47 29.56
2 INT64076 Positive_regulation of Kcnma1 47 0.40 11.52 24.19
3 INT7458 Negative_regulation of Kcnma1 30 0.43 6.61 10.4
4 INT13051 Regulation of Kcnma1 12 0.12 2.09 5.06
5 INT79682 Gene_expression of Grm7 6 0.75 4.74 4.5
6 INT79680 Binding of Grm7 6 0.47 2.83 3.58
7 INT91471 Positive_regulation of Gene_expression of Kcnma1 4 0.22 2.88 2.56
8 INT64075 Positive_regulation of Positive_regulation of Kcnma1 2 0.02 0.55 1.96
9 INT122435 Positive_regulation of Grm7 3 0.00 1.89 1.79
10 INT79683 Negative_regulation of Grm7 3 0.41 2.22 1.75
11 INT79681 Localization of Grm7 5 0.78 2.57 1.34
12 INT130323 Regulation of Grm7 3 0.26 1.9 1.21
13 INT72255 Binding of Kcnma1 4 0.02 0.2 0.99
14 INT158378 Transcription of Grm7 1 0.00 0.65 0.94
15 INT7457 Localization of Kcnma1 3 0.60 2.75 0.85
16 INT139928 Negative_regulation of Kcnma1 6 0.37 1.19 0.84
17 INT69771 Positive_regulation of Kcnma1 6 0.52 0.31 0.74
18 INT215809 Gene_expression of Kcnma1 11 0.58 0.53 0.66
19 INT288019 Regulation of Gene_expression of Kcnma1 3 0.00 0.7 0.63
20 INT154199 Regulation of Localization of Grm7 1 0.60 0.92 0.62
21 INT101705 Negative_regulation of Positive_regulation of Kcnma1 2 0.03 0 0.59
22 INT120995 Positive_regulation of Gene_expression of Grm7 1 0.00 0.57 0.57
23 INT307752 Negative_regulation of Regulation of Kcnma1 1 0.01 0.18 0.52
24 INT320019 Regulation of Positive_regulation of Kcnma1 1 0.01 0.05 0.49
25 INT99793 Regulation of Negative_regulation of Kcnma1 1 0.01 0.1 0.3
26 INT288561 Regulation of Kcnma1 5 0.21 0.49 0.26
27 INT72251 Phosphorylation of Kcnma1 2 0.05 0.07 0.13
28 INT288560 Binding of Kcnma1 1 0.16 0.16 0.05
29 INT288573 Regulation of Gene_expression of Kcnma1 1 0.21 0 0.04
30 INT288559 Regulation of Positive_regulation of Kcnma1 1 0.21 0 0
31 INT288577 Regulation of Localization of Kcnma1 1 0.21 0 0
32 INT295285 Positive_regulation of Negative_regulation of Kcnma1 1 0.08 0 0
33 INT288568 Regulation of Regulation of Kcnma1 1 0.09 0 0
34 INT288567 Localization of Kcnma1 1 0.27 0 0
35 INT253798 Protein_catabolism of Kcnma1 1 0.57 0 0
36 INT288566 Negative_regulation of Binding of Kcnma1 1 0.15 0 0
37 INT202851 Positive_regulation of Negative_regulation of Kcnma1 1 0.01 0.38 0
38 INT286831 Positive_regulation of Positive_regulation of Kcnma1 1 0.38 0.08 0
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