GO:0048821

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Name erythrocyte development
Categary Process
Go Slim No
Go Link GO:0048821
Unique Molecular Interactions 49
Total Molecular Interactions 63
Total Single Events 441
Pain Genes Associated 17

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for erythrocyte development. They are ordered first by their pain relevance and then by number of times they were reported for erythrocyte development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT31776 Positive_regulation of Gclc Positive_regulation of G6pd 1 0.29 0.19 0.75
2 INT46788 Chrna7 Positive_regulation of G6pd 1 0.50 0 0.33
3 INT93833 Binding of Fos and Srf 1 0.00 0 0.3
4 INT93832 Binding of Elk1 and Srf 1 0.00 0 0.29
5 INT118418 Gata1 Positive_regulation of Transcription of Tac2 1 0.61 0.77 0.25
6 INT118419 Binding of Gata1 and Tac2 1 0.31 0.7 0.24
7 INT115142 TGM7 Positive_regulation of Gene_expression of CITED2 1 0.02 0.45 0.2
8 INT179846 Il11 Regulation of Positive_regulation of Rps6 1 0.04 0.07 0.17
9 INT178269 Slc11a2 Regulation of a 1 0.06 0.97 0.16
10 INT156833 Binding of MED1 and TRPV6 1 0.32 0 0.15
11 INT156837 Binding of CYP24A1 and MED1 1 0.47 0 0.15
12 INT350723 MIR219-1 Negative_regulation of Sox6 1 0.01 0.4 0.15
13 INT204159 Slc11a2 Regulation of Gene_expression of HAMP 1 0.11 1.08 0.14
14 INT288701 Epas1 Regulation of Transcription of Slc11a2 1 0.29 0.38 0.13
15 INT214012 Binding of Ank1 and Nav1 1 0.01 0.51 0.1
16 INT214011 Negative_regulation of Binding of Ank1 and Nav1 1 0.01 0.51 0.1
17 INT350700 Binding of Bcl6 and thd 1 0.00 0.21 0.08
18 INT68008 Binding of DES and Hba-a1 1 0.03 1.3 0.08
19 INT68004 Binding of Hba-a1 and Vim 1 0.00 1.3 0.08
20 INT350692 Binding of Bcl6 and Hand1 1 0.02 0.16 0.08
21 INT350720 Binding of Bcl6 and TBX21 1 0.07 0.22 0.08
22 INT216130 SRF Positive_regulation of Gene_expression of EGR1 1 0.49 0.32 0.07
23 INT216129 SRF Positive_regulation of Gene_expression of FOS 1 0.28 0.32 0.07
24 INT118417 Gata1 Regulation of Gene_expression of Serpinb9g 1 0.17 0.12 0.06
25 INT225490 Med1 Positive_regulation of Ppara 1 0.12 0.26 0.06
26 INT319558 Positive_regulation of Creb1 Regulation of Srf 1 0.31 0.06 0.04
27 INT319559 Creb1 Regulation of Srf 1 0.28 0.06 0.04
28 INT261393 Binding of Nsdhl and Med1 1 0.02 1 0.04
29 INT184209 IL1B Negative_regulation of Gene_expression of SOX6 1 0.46 0.05 0.03
30 INT225585 Regulation of Binding of Med1 and Tpr 1 0.00 0.07 0
31 INT132849 Homer1 Regulation of Srf 1 0.01 0.15 0
32 INT188067 Rps6kb1 Regulation of Rps6 1 0.10 0.1 0
33 INT177262 Binding of MED1 and SV2A 1 0.23 0 0
34 INT190632 Binding of Srf and Yy1 1 0.20 0.14 0
35 INT330048 G6pd Positive_regulation of Gene_expression of Ros1 1 0.03 0.61 0
36 INT225590 Ncoa6 Regulation of Srf 1 0.08 0.21 0
37 INT225481 Binding of Med1 and Acp5 1 0.16 0 0
38 INT177286 Binding of CXADR and MED1 1 0.27 0 0
39 INT304168 Binding of Gata1 and Sfpi1 1 0.08 0.07 0
40 INT192618 Atrx Regulation of Gene_expression of Hba-a1 1 0.08 0.45 0
41 INT225541 Binding of Med1 and Tpr 1 0.00 0.07 0
42 INT207266 INS Negative_regulation of BCL6 1 0.29 0.08 0
43 INT322470 Binding of Bcl6 and Hif1a 1 0.06 0.52 0
44 INT305632 Binding of BCL6 and MME 1 0.00 1.37 0
45 INT177280 Binding of MED1 and FAUP1 1 0.01 0 0
46 INT268508 MIR221 Positive_regulation of BCL6 1 0.03 1.36 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for erythrocyte development. They are ordered first by their pain relevance and then by number of times they were reported in erythrocyte development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5409 Negative_regulation of G6pd 33 0.57 29.21 7.64
2 INT5411 Positive_regulation of G6pd 20 0.70 4.74 5.11
3 INT30031 Gene_expression of Hba-a1 7 0.60 7.46 4.41
4 INT5412 Regulation of G6pd 9 0.62 1.64 2.87
5 INT4114 Gene_expression of Srf 9 0.70 6.11 2.63
6 INT10447 Negative_regulation of Srf 3 0.40 0.95 1.98
7 INT126457 Gene_expression of BCL6 34 0.66 22.45 1.75
8 INT118412 Gene_expression of Gata1 5 0.62 0.83 1.6
9 INT118413 Positive_regulation of Gene_expression of Gata1 3 0.40 0.68 1.56
10 INT46786 Positive_regulation of Positive_regulation of G6pd 3 0.47 0.47 1.52
11 INT129179 Gene_expression of Ank1 4 0.31 0.47 1.35
12 INT5410 Gene_expression of G6pd 15 0.75 4.59 1.28
13 INT10448 Positive_regulation of Srf 3 0.47 0.89 1.03
14 INT135032 Negative_regulation of SRF 1 0.49 0 1.03
15 INT26531 Regulation of Srf 3 0.18 0.62 0.9
16 INT132883 Gene_expression of Slc11a2 5 0.75 2.96 0.89
17 INT17855 Binding of G6pd 4 0.34 1.42 0.8
18 INT132127 Positive_regulation of Rps6 1 0.49 0.32 0.79
19 INT45293 Transcription of Srf 2 0.47 0.79 0.76
20 INT45489 Gene_expression of SRF 5 0.77 3.29 0.71
21 INT144995 Positive_regulation of Gata1 1 0.37 0.14 0.71
22 INT45292 Negative_regulation of Transcription of Srf 1 0.06 0.65 0.59
23 INT236711 Gene_expression of Bcl6 15 0.30 12.98 0.58
24 INT35131 Regulation of Hba-a1 3 0.45 0.93 0.58
25 INT31603 Regulation of Gene_expression of G6pd 1 0.59 0 0.43
26 INT207299 Binding of BCL6 6 0.30 3.5 0.41
27 INT132128 Positive_regulation of Phosphorylation of Rps6 1 0.49 0.16 0.4
28 INT145045 Gene_expression of Med1 29 0.65 5.37 0.39
29 INT132126 Phosphorylation of Rps6 1 0.80 0.16 0.39
30 INT233917 Gene_expression of MED1 2 0.20 0.17 0.38
31 INT46787 Regulation of Regulation of G6pd 1 0.24 0 0.36
32 INT121388 Positive_regulation of BCL6 2 0.28 2.71 0.32
33 INT18821 Positive_regulation of Gene_expression of Srf 2 0.35 0.63 0.31
34 INT235466 Localization of BCL6 3 0.27 5 0.29
35 INT106734 Phosphorylation of MED1 4 0.74 1.65 0.28
36 INT7610 Localization of Srf 3 0.67 0.98 0.27
37 INT28132 Phosphorylation of Hba-a1 1 0.55 0.1 0.22
38 INT115160 Gene_expression of CITED2 1 0.04 0.45 0.2
39 INT115153 Positive_regulation of Gene_expression of CITED2 1 0.02 0.45 0.2
40 INT144881 Positive_regulation of Gene_expression of BCL6 5 0.43 1.6 0.18
41 INT179828 Regulation of Positive_regulation of Rps6 1 0.04 0.07 0.17
42 INT106730 Regulation of Phosphorylation of MED1 2 0.24 0.7 0.16
43 INT179805 Positive_regulation of Rps6 1 0.10 0.07 0.16
44 INT204148 Regulation of Gene_expression of Slc11a2 1 0.15 1.1 0.15
45 INT89766 Binding of SRF 1 0.17 0.89 0.15
46 INT89767 Positive_regulation of Binding of SRF 1 0.23 0.89 0.15
47 INT236693 Positive_regulation of Gene_expression of Bcl6 3 0.15 2.06 0.14
48 INT220570 Transcription of Gata1 2 0.05 0.91 0.14
49 INT258953 Negative_regulation of Gene_expression of Bcl6 1 0.19 1.53 0.14
50 INT288681 Regulation of Transcription of Slc11a2 1 0.44 0.37 0.13
51 INT288683 Transcription of Slc11a2 1 0.69 0.37 0.13
52 INT254335 Gene_expression of Sox6 2 0.43 0.25 0.12
53 INT288682 Binding of Slc11a2 1 0.47 0 0.12
54 INT106731 Negative_regulation of Phosphorylation of MED1 1 0.02 0.96 0.12
55 INT258955 Localization of Bcl6 1 0.23 0.83 0.11
56 INT214008 Negative_regulation of Ank1 4 0.03 1.49 0.09
57 INT30032 Positive_regulation of Hba-a1 2 0.46 0.32 0.09
58 INT22380 Binding of Hba-a1 1 0.42 0.84 0.09
59 INT350635 Transcription of Bcl6 1 0.09 0.16 0.08
60 INT350649 Negative_regulation of Transcription of Bcl6 1 0.06 0.16 0.08
61 INT156864 Positive_regulation of Phosphorylation of MED1 1 0.45 0 0.07
62 INT22789 Binding of Srf 1 0.37 0.07 0.07
63 INT22790 Positive_regulation of Binding of Srf 1 0.50 0.07 0.07
64 INT190544 Transcription of Srf 1 0.19 0.43 0.06
65 INT190570 Localization of Srf 1 0.20 0.49 0.06
66 INT8558 Negative_regulation of Hba-a1 2 0.11 0.57 0.05
67 INT159766 Positive_regulation of Ank1 1 0.07 0.1 0.04
68 INT208887 Regulation of Ank1 1 0.01 0.08 0.04
69 INT354957 Binding of Ank1 1 0.02 0 0.04
70 INT184219 Gene_expression of SOX6 4 0.59 0.13 0.03
71 INT207276 Transcription of BCL6 3 0.45 0.64 0.03
72 INT229428 Localization of G6pd 2 0.73 0 0.03
73 INT225411 Positive_regulation of Srf 1 0.05 0.27 0.03
74 INT297433 Phosphorylation of G6pd 1 0.06 0.12 0.03
75 INT289614 Positive_regulation of CITED2 1 0.37 0.41 0.03
76 INT268102 Transcription of SRF 1 0.53 0.85 0.03
77 INT225413 Binding of Srf 1 0.10 0.27 0.03
78 INT271907 Phosphorylation of Rps6 4 0.09 0.67 0
79 INT307189 Localization of Med1 3 0.53 0.32 0
80 INT157800 Gene_expression of Srf 2 0.45 0.88 0
81 INT144882 Negative_regulation of Gene_expression of BCL6 2 0.26 0.93 0
82 INT225400 Positive_regulation of Gene_expression of Med1 2 0.35 0.82 0
83 INT322454 Positive_regulation of Bcl6 2 0.10 1.6 0
84 INT269895 Binding of Sox6 2 0.27 0.33 0
85 INT225358 Negative_regulation of Gene_expression of Med1 2 0.30 1.16 0
86 INT271935 Positive_regulation of Phosphorylation of Rps6 1 0.02 0.17 0
87 INT177336 Positive_regulation of Binding of MED1 1 0.24 0 0
88 INT307197 Negative_regulation of Med1 1 0.30 0.7 0
89 INT105753 Positive_regulation of Gene_expression of SRF 1 0.01 0.13 0
90 INT271551 Localization of Ank1 1 0.03 0.11 0
91 INT192611 Negative_regulation of Gene_expression of Hba-a1 1 0.07 0.86 0
92 INT337050 Negative_regulation of Phosphorylation of Rps6 1 0.06 0 0
93 INT307188 Transcription of Med1 1 0.48 0.7 0
94 INT207269 Regulation of BCL6 1 0.38 0.1 0
95 INT184226 Regulation of Negative_regulation of SOX6 1 0.34 0 0
96 INT185701 Negative_regulation of Gene_expression of G6pd 1 0.12 0.23 0
97 INT225389 Regulation of Binding of Med1 1 0.17 0.07 0
98 INT177320 Binding of MED1 1 0.25 0 0
99 INT251809 Localization of SOX6 1 0.45 0 0
100 INT313601 Regulation of CITED2 1 0.00 0.8 0
101 INT225457 Binding of Med1 1 0.35 0.28 0
102 INT184225 Regulation of Gene_expression of SOX6 1 0.47 0 0
103 INT277796 Binding of Bcl6 1 0.17 1.33 0
104 INT105752 Positive_regulation of SRF 1 0.01 0.13 0
105 INT341851 Positive_regulation of MED1 1 0.01 0.5 0
106 INT308843 Regulation of Phosphorylation of Rps6 1 0.03 0.16 0
107 INT334482 Regulation of Gene_expression of Med1 1 0.17 0.1 0
108 INT347438 Regulation of Gene_expression of BCL6 1 0.07 0.7 0
109 INT268104 Negative_regulation of Gene_expression of SRF 1 0.38 0.16 0
110 INT337051 Negative_regulation of Rps6 1 0.06 0.29 0
111 INT213446 Regulation of Gene_expression of SRF 1 0.22 0.71 0
112 INT184224 Negative_regulation of Gene_expression of SOX6 1 0.44 0 0
113 INT192612 Regulation of Gene_expression of Hba-a1 1 0.07 0.99 0
114 INT262679 Phosphorylation of Gata1 1 0.18 0.55 0
115 INT352006 Negative_regulation of Sox6 1 0.31 0.08 0
116 INT225408 Negative_regulation of Srf 1 0.05 0.39 0
117 INT184221 Negative_regulation of SOX6 1 0.32 0 0
118 INT157799 Negative_regulation of Gene_expression of Srf 1 0.18 0.07 0
119 INT262696 Binding of Gata1 1 0.08 0.56 0
120 INT334481 Negative_regulation of Localization of Med1 1 0.16 0.09 0
121 INT157794 Phosphorylation of Srf 1 0.26 0.07 0
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