GO:0048842

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Name positive regulation of axon extension involved in axon guidance
Categary Process
Go Slim No
Go Link GO:0048842
Unique Molecular Interactions 39
Total Molecular Interactions 53
Total Single Events 307
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of axon extension involved in axon guidance. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of axon extension involved in axon guidance. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17
2 INT149844 Negative_regulation of Cxcl12 Negative_regulation of C19orf10 1 0.16 0.45 1.26
3 INT149845 Cxcl12 Negative_regulation of C19orf10 1 0.16 0.45 1.24
4 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
5 INT105109 Cxcl12 Positive_regulation of JUN 1 0.01 1.07 1.05
6 INT166135 Regulation of Binding of Cxcl12 and Cxcr4 1 0.30 0.9 0.91
7 INT253992 Cxcl12 Positive_regulation of Mif 1 0.46 1.31 0.88
8 INT254004 Cxcl12 Positive_regulation of Cxcr4 1 0.47 1.29 0.86
9 INT253995 Binding of Cxcl12 and Cyp3a23/3a1 1 0.06 1.28 0.85
10 INT253998 Cyp3a23/3a1 Positive_regulation of Binding of Cxcl12 1 0.10 0.65 0.55
11 INT253990 Cyp3a23/3a1 Positive_regulation of Cxcl12 1 0.09 0.65 0.55
12 INT105110 Cxcl12 Positive_regulation of NFKB1 1 0.06 0.54 0.53
13 INT105108 Negative_regulation of Cxcl12 Positive_regulation of NFKB1 1 0.05 0.54 0.53
14 INT181441 Csf2 Positive_regulation of Cxcl12 1 0.02 1.69 0.39
15 INT322964 Binding of IL8 and Cxcl12 1 0.30 0.2 0.32
16 INT333246 Binding of Cxcr4 and Cxcl12 3 0.34 0.99 0.27
17 INT253991 Negative_regulation of Binding of Cxcl12 and Cxcr4 1 0.43 0.41 0.21
18 INT333250 Binding of Cxcr7 and Cxcl12 1 0.19 1.39 0.18
19 INT353361 Positive_regulation of Binding of Cxcr4 and Cxcl12 1 0.46 0 0.17
20 INT333255 Cxcl12 Regulation of Mcl1 1 0.12 1.12 0.15
21 INT333241 Cxcl12 Regulation of Bcl2l11 1 0.18 1.11 0.15
22 INT353359 Binding of Cxcl12 and Regulation of Nes 1 0.25 0.3 0.15
23 INT353360 Binding of Cxcl12 and Positive_regulation of Gene_expression of Hist1h3f 1 0.03 0.3 0.15
24 INT333242 Bcl2l11 Positive_regulation of Gene_expression of Cxcl12 1 0.18 1.48 0.1
25 INT333251 Binding of Bcl2l11 and Cxcl12 1 0.14 1.74 0.08
26 INT249968 Cxcr4 Positive_regulation of Cxcl12 1 0.17 0.55 0.08
27 INT333256 Gene_expression of Cxcl12 Negative_regulation of Ptk2b 1 0.10 0.99 0.07
28 INT333260 Gene_expression of Cxcl12 Negative_regulation of Gene_expression of Ptk2 1 0.21 1 0.07
29 INT333247 Gene_expression of Cxcl12 Negative_regulation of Pxn 1 0.09 1 0.07
30 INT333243 Gene_expression of Cxcl12 Negative_regulation of Bcar1 1 0.15 1 0.07
31 INT333257 Gene_expression of Cxcl12 Negative_regulation of Ptk2 1 0.21 1 0.07
32 INT333254 Binding of Mcl1 and Cxcl12 1 0.10 0.88 0.04
33 INT333244 Positive_regulation of Binding of Mcl1 and Cxcl12 1 0.13 0.88 0.04
34 INT333249 Cxcl12 Positive_regulation of Positive_regulation of Bak1 1 0.30 0.32 0.03
35 INT333258 Gene_expression of Cxcl12 Positive_regulation of Positive_regulation of Bak1 1 0.15 0.55 0
36 INT299130 Cxcl12 Positive_regulation of Gene_expression of Fgf2 1 0.15 0.38 0
37 INT299140 Cxcl12 Positive_regulation of Transcription of VEGFA 1 0.03 0.38 0
38 INT333248 Bcl2l11 Regulation of Gene_expression of Cxcl12 1 0.11 0.52 0
39 INT299129 Cxcl12 Positive_regulation of Transcription of Fgf2 1 0.16 0.38 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of axon extension involved in axon guidance. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of axon extension involved in axon guidance. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT222233 Gene_expression of Cxcl12 42 0.69 32.64 10.13
2 INT126478 Gene_expression of Cxcl12 78 0.77 58.69 8.01
3 INT136309 Positive_regulation of Cxcl12 24 0.62 12.45 5.58
4 INT253983 Binding of Cxcl12 8 0.43 5.33 3.71
5 INT181386 Positive_regulation of Cxcl12 12 0.69 15.35 2.84
6 INT253982 Positive_regulation of Binding of Cxcl12 1 0.45 3.85 2.6
7 INT130638 Regulation of Cxcl12 6 0.34 2.91 2.44
8 INT222230 Positive_regulation of Gene_expression of Cxcl12 11 0.59 5.26 2.13
9 INT297679 Positive_regulation of Gene_expression of Cxcl12 6 0.69 8.02 2.02
10 INT253972 Positive_regulation of Positive_regulation of Cxcl12 1 0.45 3.22 1.71
11 INT222227 Localization of Cxcl12 5 0.64 1.61 1.59
12 INT254252 Localization of Cxcl12 9 0.76 7.17 1.49
13 INT211294 Binding of Cxcl12 4 0.45 2.89 1.05
14 INT222231 Transcription of Cxcl12 4 0.55 2.25 0.91
15 INT300848 Negative_regulation of Cxcl12 3 0.40 2.29 0.69
16 INT333232 Negative_regulation of Gene_expression of Cxcl12 4 0.42 3.35 0.57
17 INT222238 Regulation of Localization of Cxcl12 1 0.22 0.6 0.55
18 INT136310 Negative_regulation of Cxcl12 3 0.37 3.29 0.51
19 INT280914 Positive_regulation of Localization of Cxcl12 3 0.44 3.99 0.47
20 INT281148 Negative_regulation of Transcription of Cxcl12 1 0.26 1.12 0.47
21 INT281140 Regulation of Binding of Cxcl12 1 0.28 0.93 0.47
22 INT281149 Positive_regulation of Localization of Cxcl12 1 0.31 0.42 0.45
23 INT274228 Positive_regulation of Positive_regulation of Cxcl12 4 0.44 2.82 0.23
24 INT299139 Positive_regulation of Transcription of Cxcl12 1 0.37 0.28 0.21
25 INT333239 Regulation of Gene_expression of Cxcl12 1 0.43 3.48 0.19
26 INT253969 Regulation of Gene_expression of Cxcl12 3 0.40 1.56 0.15
27 INT253981 Negative_regulation of Gene_expression of Cxcl12 3 0.39 1.7 0.13
28 INT233555 Regulation of Cxcl12 2 0.43 4.12 0.13
29 INT299136 Protein_catabolism of Cxcl12 1 0.56 1.15 0.09
30 INT353357 Regulation of Positive_regulation of Cxcl12 1 0.27 0.62 0.08
31 INT333206 Negative_regulation of Localization of Cxcl12 1 0.41 1.11 0.08
32 INT333233 Negative_regulation of Positive_regulation of Cxcl12 1 0.41 1.11 0.08
33 INT333210 Regulation of Localization of Cxcl12 1 0.58 0.56 0
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