GO:0048853

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Name forebrain morphogenesis
Categary Process
Go Slim No
Go Link GO:0048853
Unique Molecular Interactions 47
Total Molecular Interactions 78
Total Single Events 328
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for forebrain morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported for forebrain morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
2 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
3 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93
4 INT250861 Fgf8 Positive_regulation of Gene_expression of Ptger2 1 0.04 1.51 0.84
5 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
6 INT250852 Fgf8 Negative_regulation of Gene_expression of Ecm1 1 0.04 1.1 0.54
7 INT250870 Fgf8 Positive_regulation of Ecm1 1 0.04 0.79 0.38
8 INT297342 Binding of Gnb5 and Smo 1 0.02 1.67 0.34
9 INT191616 Binding of Cbln1 and Nf1 1 0.01 0.2 0.32
10 INT191620 Binding of Nf1 and Gopc 1 0.08 0.2 0.32
11 INT191611 Nf1 Regulation of ras 1 0.26 0.18 0.3
12 INT229635 SPINK5 Positive_regulation of NF1 1 0.01 2.17 0.3
13 INT250856 Fgf8 Positive_regulation of Localization of Mmp3 1 0.11 0.51 0.3
14 INT250864 Fgf8 Positive_regulation of Positive_regulation of Ptger2 1 0.03 0.55 0.28
15 INT250854 Fgf8 Positive_regulation of Positive_regulation of Mmp3 1 0.11 0.55 0.28
16 INT250873 Fgf8 Positive_regulation of GAG 1 0.55 0.48 0.23
17 INT103197 Nf1 Negative_regulation of ras 1 0.04 1.19 0.17
18 INT191615 Binding of Nf1 and Flna 1 0.08 0.53 0.17
19 INT191621 Binding of Drd3 and Nf1 1 0.32 0.53 0.17
20 INT103198 NF1 Negative_regulation of ras 1 0.05 1.19 0.16
21 INT250863 Fgf8 Positive_regulation of Ptger2 1 0.03 0.19 0.14
22 INT345343 PTCH1 Regulation of Negative_regulation of SMO 1 0.09 2.3 0.13
23 INT250866 Binding of Fgfr4 and Fgf8 1 0.12 0.35 0.11
24 INT191612 Nf1 Positive_regulation of ras 1 0.25 2.6 0.11
25 INT250860 Fgf8 Regulation of Localization of Ptger2 1 0.02 0.13 0.1
26 INT262751 Binding of PTCH1 and SMO 1 0.25 1.29 0.1
27 INT250862 Fgf8 Regulation of Localization of Mmp3 1 0.13 0.13 0.1
28 INT250859 Fgf8 Negative_regulation of Gene_expression of Mmp3 1 0.09 0.12 0.09
29 INT250872 Fgf8 Positive_regulation of Mmp3 1 0.11 0.12 0.09
30 INT191617 Binding of Nf1 and Rtcd1 1 0.01 0.95 0.08
31 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
32 INT250865 Binding of Fgf8 and Fgfr3 1 0.18 0.3 0.05
33 INT250855 Binding of Fgfr2 and Fgf8 1 0.12 0.3 0.05
34 INT262757 SMO Positive_regulation of Regulation of GLI1 1 0.34 0.6 0.04
35 INT320439 Binding of Uchl5 and Psmb10 1 0.00 0 0.04
36 INT270458 Binding of Gli1 and Smo 1 0.00 0.65 0.04
37 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
38 INT191613 Binding of Nf1 and Rasa1 1 0.06 0.88 0.03
39 INT352148 Ift88 Negative_regulation of Bcl2l2 1 0.00 0.19 0
40 INT205975 Binding of PTCH1 and Smo 1 0.02 0.72 0
41 INT205974 Smo Positive_regulation of GLI1 1 0.04 0.66 0
42 INT352525 SLC25A16 Negative_regulation of SMO 1 0.00 1.1 0
43 INT205965 Binding of Ptch1 and Smo 1 0.03 0.72 0
44 INT352150 Ift88 Negative_regulation of Bcl2 1 0.00 0.19 0
45 INT180836 Binding of CTD and NF1 1 0.15 0.2 0
46 INT352149 Ift88 Negative_regulation of Bcl2l1 1 0.00 0.19 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for forebrain morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported in forebrain morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT250832 Gene_expression of Fgf8 1 0.77 13.36 6.2
2 INT68216 Binding of NF1 40 0.48 51.24 4.59
3 INT61434 Regulation of Nf1 3 0.26 1.39 2.4
4 INT64700 Binding of Nf1 14 0.45 15.24 2.29
5 INT84510 Positive_regulation of Nf1 8 0.69 9.52 1.93
6 INT68181 Binding of Nf1 6 0.48 8.14 1.88
7 INT250841 Positive_regulation of Gene_expression of Fgf8 1 0.69 3.8 1.72
8 INT250850 Negative_regulation of Gene_expression of Fgf8 1 0.42 2.79 1.33
9 INT131645 Negative_regulation of Nf1 10 0.58 8.12 1.24
10 INT61993 Gene_expression of NF1 29 0.78 34.47 1.23
11 INT183068 Gene_expression of SMO 2 0.17 0.27 1.2
12 INT250840 Negative_regulation of Fgf8 1 0.43 1.92 1.11
13 INT277461 Positive_regulation of Gene_expression of Fgf8 1 0.24 0.47 1.05
14 INT270447 Binding of Smo 2 0.07 2.61 0.78
15 INT68179 Gene_expression of Nf1 9 0.78 8.87 0.68
16 INT179133 Localization of Nf1 2 0.80 2.18 0.68
17 INT49650 Gene_expression of Nf1 4 0.76 3.38 0.67
18 INT205957 Negative_regulation of Smo 4 0.08 2.57 0.6
19 INT61992 Positive_regulation of Gene_expression of NF1 3 0.50 4.47 0.51
20 INT250845 Protein_catabolism of Fgf8 1 0.98 1.64 0.48
21 INT268007 Gene_expression of Fgf8 8 0.72 1.38 0.47
22 INT316933 Transcription of Nf1 1 0.18 0.49 0.47
23 INT316939 Positive_regulation of Transcription of Nf1 1 0.16 0.49 0.47
24 INT277465 Regulation of Gene_expression of Fgf8 2 0.25 0.43 0.43
25 INT112334 Regulation of NF1 18 0.52 15.85 0.34
26 INT250826 Transcription of Fgf8 1 0.71 0.71 0.34
27 INT356400 Transcription of Smo 1 0.02 0.05 0.3
28 INT277474 Positive_regulation of Gene_expression of SMO 1 0.11 0 0.29
29 INT216120 Negative_regulation of SMO 2 0.49 3.05 0.27
30 INT250836 Binding of Fgf8 3 0.35 0.66 0.24
31 INT129342 Positive_regulation of Positive_regulation of Nf1 1 0.50 0.79 0.23
32 INT68180 Regulation of Nf1 2 0.27 2.02 0.22
33 INT250833 Localization of Fgf8 1 0.74 0.46 0.21
34 INT250842 Negative_regulation of Binding of Fgf8 1 0.43 0.33 0.21
35 INT177938 Negative_regulation of NF1 9 0.43 10.3 0.2
36 INT129341 Negative_regulation of Gene_expression of Nf1 2 0.43 1.67 0.2
37 INT155285 Positive_regulation of Nf1 1 0.16 0.55 0.17
38 INT103196 Negative_regulation of Gene_expression of Nf1 1 0.57 1.21 0.16
39 INT250835 Positive_regulation of Fgf8 1 0.50 0.42 0.14
40 INT61991 Negative_regulation of Gene_expression of NF1 1 0.59 1.67 0.08
41 INT190026 Positive_regulation of Gene_expression of Nf1 3 0.53 2.45 0.07
42 INT345344 Regulation of SMO 1 0.23 1.07 0.06
43 INT352129 Negative_regulation of Ift88 1 0.00 0.72 0.05
44 INT262772 Binding of SMO 1 0.27 0.59 0.05
45 INT262777 Localization of SMO 1 0.59 0.6 0.04
46 INT320365 Binding of Uchl5 1 0.02 0 0.04
47 INT169558 Positive_regulation of NF1 13 0.59 13.58 0
48 INT112333 Localization of NF1 2 0.51 0.63 0
49 INT216268 Positive_regulation of Positive_regulation of NF1 2 0.40 2.08 0
50 INT252242 Gene_expression of Smo 1 0.01 0.23 0
51 INT286555 Binding of Ift88 1 0.30 0.08 0
52 INT286141 Negative_regulation of Negative_regulation of NF1 1 0.01 0.66 0
53 INT286544 Localization of Ift88 1 0.52 1.26 0
54 INT250830 Regulation of Protein_catabolism of Fgf8 1 0.45 0.08 0
55 INT311651 Positive_regulation of Fgf8 1 0.46 0.26 0
56 INT237279 Regulation of Binding of NF1 1 0.38 0.79 0
57 INT205956 Localization of Smo 1 0.06 0.71 0
58 INT250846 Positive_regulation of Protein_catabolism of Fgf8 1 0.50 0.07 0
59 INT177934 Regulation of Gene_expression of NF1 1 0.19 1.23 0
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