GO:0048859

From wiki-pain
Jump to: navigation, search
Name formation of anatomical boundary
Categary Process
Go Slim No
Go Link GO:0048859
Unique Molecular Interactions 53
Total Molecular Interactions 69
Total Single Events 456
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for formation of anatomical boundary. They are ordered first by their pain relevance and then by number of times they were reported for formation of anatomical boundary. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
2 INT333449 Binding of SMAD2 and SMAD4 1 0.23 0 0.17
3 INT172976 Mras Regulation of Gene_expression of Smad4 1 0.00 0.83 0.12
4 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
5 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
6 INT298349 HES3 Positive_regulation of Shh 1 0.12 0.14 0.07
7 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
8 INT311906 Binding of Smad4 and Insrr 1 0.00 0.18 0.06
9 INT353290 Binding of Smad2 and Smad4 1 0.20 0.08 0.04
10 INT353295 Binding of Smad3 and Smad4 1 0.17 0.08 0.04
11 INT213563 Binding of Ctnnd2 and Shh 1 0.27 0.09 0.04
12 INT270459 Binding of Shh and Gli1 1 0.02 0.65 0.04
13 INT352014 Shh Positive_regulation of Gene_expression of Pax1 1 0.29 0.07 0.03
14 INT280263 Binding of Smad4 and Proc 1 0.00 1.26 0.03
15 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
16 INT270462 Shh Positive_regulation of Ccnd1 1 0.10 0.6 0.03
17 INT213559 Binding of Egf and Shh 1 0.17 0.07 0.03
18 INT277927 WIF1 Negative_regulation of SMAD4 1 0.23 0.37 0
19 INT290910 Pkm2 Negative_regulation of Shh 1 0.07 0.06 0
20 INT205963 GLI1 Positive_regulation of Negative_regulation of SHH 1 0.22 0.58 0
21 INT314850 Shh Regulation of Atoh7 1 0.45 0.22 0
22 INT290908 Regulation of Shh Positive_regulation of Ntn1 1 0.12 0 0
23 INT290911 Gene_expression of Shh Positive_regulation of Pkm2 1 0.07 0 0
24 INT290904 Shh Positive_regulation of Prkcg 1 0.26 0.06 0
25 INT290900 Prkcg Regulation of Shh 1 0.23 0 0
26 INT205960 Binding of PTCH1 and SHH 1 0.21 0.71 0
27 INT290944 Shh Positive_regulation of VEGFA 1 0.04 0.05 0
28 INT270461 Shh Regulation of Gene_expression of Ptch1 1 0.48 0.07 0
29 INT268341 SMAD2 Positive_regulation of SMAD4 1 0.31 0.56 0
30 INT205959 Binding of SHH and SMOX 1 0.12 0.72 0
31 INT270471 Shh Regulation of VEGFA 1 0.39 0.08 0
32 INT290898 Shh Positive_regulation of Nos2 1 0.46 0.05 0
33 INT270466 Ptch1 Regulation of Gene_expression of Shh 1 0.48 0.07 0
34 INT270460 Shh Positive_regulation of Gene_expression of Angpt1 1 0.04 0.08 0
35 INT270470 Shh Regulation of Gene_expression of VEGFA 1 0.39 0.15 0
36 INT290907 Shh Positive_regulation of Ntn1 1 0.32 0.05 0
37 INT205977 Binding of SHH and Ptch1 1 0.31 0.71 0
38 INT268344 SMAD3 Positive_regulation of SMAD4 1 0.17 0.56 0
39 INT270469 Shh Positive_regulation of VEGFA 1 0.29 0.12 0
40 INT172981 PAN3 Negative_regulation of SMAD4 1 0.01 0.98 0
41 INT270468 Shh Positive_regulation of Gene_expression of VEGFA 1 0.44 0.08 0
42 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for formation of anatomical boundary. They are ordered first by their pain relevance and then by number of times they were reported in formation of anatomical boundary. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
2 INT107178 Gene_expression of Smad4 12 0.65 9.85 1.92
3 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
4 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
5 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
6 INT172960 Negative_regulation of Gene_expression of Smad4 7 0.39 5.88 0.71
7 INT103781 Negative_regulation of Smad4 9 0.42 4.42 0.54
8 INT206484 Localization of Shh 2 0.75 1.14 0.46
9 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
10 INT71019 Negative_regulation of SMAD4 12 0.42 6.88 0.43
11 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
12 INT117564 Gene_expression of SMAD4 12 0.71 8.7 0.37
13 INT92100 Binding of Smad4 5 0.31 2.23 0.3
14 INT232795 Positive_regulation of Shh 2 0.70 3.68 0.26
15 INT183062 Gene_expression of SHH 12 0.65 5.28 0.21
16 INT134477 Negative_regulation of SHH 2 0.37 1.13 0.2
17 INT277935 Binding of SMAD4 4 0.28 1.12 0.17
18 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16
19 INT253177 Negative_regulation of Gene_expression of Shh 2 0.55 0.63 0.16
20 INT139977 Regulation of Smad4 1 0.16 1.41 0.15
21 INT253190 Localization of Shh 2 0.77 1.06 0.13
22 INT253183 Negative_regulation of Shh 8 0.55 2.13 0.12
23 INT270442 Transcription of Shh 1 0.53 0.25 0.09
24 INT325510 Transcription of Smad4 1 0.67 0.16 0.09
25 INT213515 Binding of Shh 8 0.37 1.92 0.08
26 INT270453 Regulation of Shh 1 0.27 0.83 0.08
27 INT205973 Binding of SHH 3 0.35 1.03 0.07
28 INT256862 Regulation of Shh 1 0.25 0 0.07
29 INT254790 Localization of Smad4 2 0.37 0.54 0.06
30 INT270445 Positive_regulation of Localization of Shh 1 0.44 0.13 0.05
31 INT181793 Positive_regulation of SHH 3 0.67 2.59 0.04
32 INT208560 Negative_regulation of Shh 2 0.59 2.22 0.04
33 INT334291 Positive_regulation of Gene_expression of SMAD4 1 0.18 0 0.04
34 INT268360 Positive_regulation of SMAD4 3 0.55 1.55 0.03
35 INT253187 Negative_regulation of Transcription of Shh 1 0.41 0.55 0.03
36 INT253181 Transcription of Shh 1 0.68 0.54 0.03
37 INT117563 Negative_regulation of Gene_expression of SMAD4 6 0.54 3.87 0
38 INT334327 Regulation of SMAD4 2 0.35 1.73 0
39 INT268368 Transcription of SMAD4 1 0.54 1.7 0
40 INT173000 Negative_regulation of Localization of SMAD4 1 0.22 0.98 0
41 INT173008 Localization of SMAD4 1 0.38 0.97 0
42 INT290918 Negative_regulation of Positive_regulation of Shh 1 0.41 0.25 0
43 INT334289 Regulation of Binding of SMAD4 1 0.16 0 0
44 INT334288 Regulation of Negative_regulation of SMAD4 1 0.16 0 0
45 INT228250 Positive_regulation of Smad4 1 0.45 1.93 0
46 INT230972 Positive_regulation of Gene_expression of SHH 1 0.18 0.07 0
47 INT290929 Binding of Shh 1 0.31 0.1 0
48 INT290927 Regulation of Positive_regulation of Shh 1 0.23 0 0
49 INT228247 Regulation of Positive_regulation of Smad4 1 0.26 0.97 0
50 INT270449 Negative_regulation of Positive_regulation of Shh 1 0.43 0.24 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox