GO:0048870

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Name cell motility
Categary Process
Go Slim Yes
Go Link GO:0048870
Unique Molecular Interactions 322
Total Molecular Interactions 401
Total Single Events 3576
Pain Genes Associated 24

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cell motility. They are ordered first by their pain relevance and then by number of times they were reported for cell motility. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT134215 CRH Positive_regulation of ENG 1 0.13 1.22 2.06
2 INT281381 FSCN1 Positive_regulation of Gene_expression of Gfap 1 0.06 1.13 1.98
3 INT134686 FSCN1 Positive_regulation of Gfap 1 0.00 0.71 1.89
4 INT122964 FSCN1 Positive_regulation of Bdnf 1 0.01 1.14 1.79
5 INT31445 ENG Positive_regulation of Localization of Prl 4 0.01 0 1.77
6 INT167321 Binding of ENG and OPRM1 1 0.27 0.63 1.76
7 INT346217 Braf Positive_regulation of Phosphorylation of Map2k1 1 0.22 3.23 1.72
8 INT199503 ENG Positive_regulation of Oprk1 1 0.01 0.87 1.69
9 INT45306 Pomc Positive_regulation of ENG 2 0.07 1.11 1.68
10 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68
11 INT45307 ENG Positive_regulation of Localization of Avp 1 0.00 0 1.45
12 INT134679 FSCN1 Positive_regulation of MAPK8 1 0.01 0.56 1.39
13 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38
14 INT281382 FSCN1 Positive_regulation of Sds 1 0.02 0.84 1.33
15 INT281383 FSCN1 Positive_regulation of Fig4 1 0.02 0.44 1.19
16 INT281379 Tcf21 Regulation of FSCN1 1 0.01 0.66 1.19
17 INT116730 Rac1 Regulation of Localization of Calca 1 0.13 1.32 1.19
18 INT125284 FSCN1 Positive_regulation of Positive_regulation of EPHB2 1 0.04 0.4 1.14
19 INT31444 ENG Positive_regulation of Prl 1 0.01 0 1.14
20 INT332776 FSCN1 Positive_regulation of Grin1 1 0.02 0.21 1.12
21 INT134213 CRH Positive_regulation of Gene_expression of ENG 1 0.13 0.61 1.03
22 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
23 INT133616 Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
24 INT133614 Map2k1 Regulation of Daxx 1 0.02 0.29 0.97
25 INT133615 Regulation of Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
26 INT281380 Fos Negative_regulation of Gene_expression of FSCN1 1 0.07 0.4 0.96
27 INT253836 Cck Regulation of DST 1 0.03 0.42 0.95
28 INT281377 FSCN1 Positive_regulation of Gene_expression of Fos 1 0.08 0.49 0.93
29 INT116930 OPRK1 Positive_regulation of Binding of PTK2 1 0.28 0.35 0.93
30 INT135446 Map2k1 Positive_regulation of Mapk3 1 0.54 0.25 0.91
31 INT32187 Binding of ENG and Negative_regulation of Localization of LH 1 0.01 0 0.91
32 INT291011 Pomc Regulation of Gene_expression of ENG 1 0.08 0.86 0.91
33 INT53152 Rac1 Regulation of Scg2 1 0.03 0 0.9
34 INT53155 Rac1 Positive_regulation of Gene_expression of Calca 1 0.06 0 0.89
35 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
36 INT117341 ADAM17 Positive_regulation of EGFR 1 0.16 3.56 0.82
37 INT102162 Binding of TNF and Adam17 1 0.14 0.88 0.78
38 INT102159 Binding of Adam17 and Mmp2 1 0.18 0.87 0.77
39 INT161951 Positive_regulation of TGFBR1 Positive_regulation of Gene_expression of Ngf 1 0.27 0.99 0.76
40 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
41 INT43662 Negative_regulation of Binding of Chrna7 and Rac1 1 0.01 0 0.73
42 INT161950 TGFBR1 Negative_regulation of Localization of Ngf 1 0.23 1.01 0.72
43 INT43661 Binding of Chrna7 and Rac1 1 0.01 0 0.72
44 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
45 INT104301 Adam17 Regulation of Negative_regulation of Sell 1 0.39 0.58 0.69
46 INT121966 HRAS Positive_regulation of RAC1 1 0.75 0.41 0.67
47 INT124477 MAP2K1 Positive_regulation of Positive_regulation of MAPK1 1 0.12 1.35 0.65
48 INT111936 Binding of PIK3CA and PTK2 1 0.19 0.67 0.65
49 INT32719 ENG Regulation of LH 2 0.00 0 0.64
50 INT111937 Binding of PIK3CG and PTK2 1 0.08 0.67 0.64
51 INT31443 ENG Positive_regulation of Localization of Pomc 1 0.00 0 0.63
52 INT330104 Binding of Sh3rf1 and Rac1 1 0.13 2.41 0.62
53 INT330101 Binding of Map3k11 and Rac1 1 0.16 2.43 0.62
54 INT89012 DST Positive_regulation of Insr 1 0.01 0.86 0.59
55 INT281378 FSCN1 Positive_regulation of Gene_expression of Fig4 1 0.02 0.22 0.56
56 INT253835 Binding of DST and Fos 1 0.02 0 0.55
57 INT134214 CRH Regulation of Localization of ENG 1 0.14 0.39 0.53
58 INT137685 Phosphorylation of Prkca Negative_regulation of Binding of Srpx2 1 0.18 0 0.53
59 INT32151 ENG Positive_regulation of Gene_expression of IFNA1 1 0.37 0 0.53
60 INT32291 ENG Negative_regulation of LH 2 0.00 0 0.52
61 INT292075 FSCN1 Positive_regulation of Gene_expression of Csnk1a1 1 0.03 0.57 0.52
62 INT302644 ARSA Positive_regulation of Gene_expression of TGFBR1 1 0.04 0.29 0.51
63 INT302647 ARSA Positive_regulation of TGFBR1 1 0.03 0.29 0.51
64 INT30618 Slc3a1 Regulation of ENG 1 0.00 0 0.5
65 INT30619 Pomc Regulation of ENG 1 0.00 0 0.5
66 INT102214 ENG Negative_regulation of HP 1 0.01 0 0.49
67 INT60872 Binding of ENG and Abat 1 0.00 0 0.49
68 INT60871 ENG Regulation of Localization of LH 1 0.00 0 0.49
69 INT131508 Gene_expression of Rac1 Positive_regulation of Trpv1 1 0.42 0.21 0.48
70 INT131503 Gene_expression of Rac1 Positive_regulation of Ngf 1 0.38 0.21 0.48
71 INT116932 PTK2 Negative_regulation of Positive_regulation of MAPK8 1 0.35 0.17 0.48
72 INT116935 Positive_regulation of OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.47
73 INT43695 ENG Regulation of Regulation of Prl 1 0.00 0 0.47
74 INT60870 ENG Negative_regulation of Localization of LH 1 0.00 0 0.47
75 INT102213 Binding of ENG and HP 1 0.01 0 0.47
76 INT116939 OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.46
77 INT116928 PTK2 Positive_regulation of JUN 1 0.20 0.15 0.46
78 INT148930 Rac1 Regulation of Chrna7 1 0.13 0.6 0.44
79 INT202516 Positive_regulation of Binding of ENG and Penk 1 0.03 0.58 0.42
80 INT131506 Rac1 Regulation of Positive_regulation of Mapk14 1 0.19 0.39 0.42
81 INT131505 Rac1 Regulation of Gene_expression of Trpv1 1 0.55 0.39 0.42
82 INT244421 Binding of DST and Ctss 1 0.02 0.42 0.41
83 INT202515 Binding of ENG and Penk 1 0.02 0.57 0.41
84 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
85 INT32720 Negative_regulation of ENG Regulation of LH 1 0.00 0 0.41
86 INT67633 Binding of DST and Gabrd 1 0.03 0 0.41
87 INT350698 Mir326 Regulation of Ets1 1 0.01 1.27 0.4
88 INT275156 Agt Positive_regulation of Rac1 1 0.03 2.89 0.4
89 INT346222 Positive_regulation of Braf Positive_regulation of Map2k1 1 0.15 0.67 0.39
90 INT330105 Rac1 Positive_regulation of Mapk8 1 0.15 1.47 0.34
91 INT25526 Dst Regulation of Gh 1 0.00 0.26 0.34
92 INT124475 MAP2K1 Positive_regulation of Positive_regulation of CPOX 1 0.04 0.68 0.33
93 INT330103 Rac1 Positive_regulation of Positive_regulation of Mapk8 1 0.14 1.24 0.32
94 INT295722 PTGER2 Positive_regulation of RAC1 1 0.02 2.14 0.32
95 INT330109 Binding of Racgap1 and Rac1 1 0.03 1.22 0.32
96 INT55404 Binding of ENG and Th 1 0.02 0 0.3
97 INT244422 Binding of DST and Fig4 1 0.01 0.42 0.29
98 INT29137 ENG Regulation of POMC 1 0.00 0 0.28
99 INT29139 ENG Regulation of Oprl1 1 0.00 0 0.28
100 INT291641 Binding of DST and ESRRG 1 0.16 1.8 0.28
101 INT118848 GNA14 Positive_regulation of RAC1 1 0.01 0.14 0.26
102 INT311918 Insrr Negative_regulation of Tgfbr1 1 0.00 0.87 0.26
103 INT32156 Binding of ENG and Oprd1 1 0.00 0 0.26
104 INT32149 Binding of ENG and LLGL1 1 0.11 0 0.26
105 INT311902 Acvrl1 Negative_regulation of Tgfbr1 1 0.13 0.87 0.26
106 INT235013 Binding of DSG1 and Adam17 1 0.07 1.34 0.26
107 INT234980 Positive_regulation of Egfr Positive_regulation of Adam17 1 0.09 1.33 0.26
108 INT43713 ENG Regulation of Prl 1 0.00 0 0.23
109 INT292561 MAP3K5 Positive_regulation of Positive_regulation of RAC1 1 0.03 0 0.23
110 INT311911 Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23
111 INT346224 Braf Negative_regulation of Phosphorylation of Map2k1 1 0.14 0.62 0.22
112 INT283858 Binding of PTK2 and APOA5 1 0.00 0.67 0.21
113 INT254687 Positive_regulation of Map2k1 Positive_regulation of Gene_expression of Mmp13 1 0.06 0.2 0.2
114 INT178086 Binding of EDNRA and PTK2 1 0.07 0.82 0.2
115 INT143973 Rac1 Positive_regulation of Vti1b 1 0.00 0.16 0.2
116 INT291642 Binding of DST and GGT1 1 0.00 1.4 0.19
117 INT254683 Positive_regulation of Map2k1 Positive_regulation of Gene_expression of Plaur 1 0.01 0.07 0.18
118 INT254698 Gopc Positive_regulation of Positive_regulation of Map2k1 1 0.06 0.07 0.18
119 INT214170 Binding of DST and Lep 1 0.02 0.17 0.18
120 INT178092 EDN3 Positive_regulation of PTK2 1 0.01 1.02 0.17
121 INT178073 EDN1 Positive_regulation of PTK2 1 0.03 1.02 0.17
122 INT304279 ETS1 Positive_regulation of MMP2 1 0.05 1.83 0.17
123 INT274353 DST Regulation of Gopc 1 0.00 0 0.17
124 INT304282 ETS1 Positive_regulation of Gene_expression of MMP2 1 0.05 1.83 0.17
125 INT304537 Map2k1 Positive_regulation of PRKG1 1 0.01 0.66 0.16
126 INT304503 Map2k1 Positive_regulation of Nos1 1 0.07 0.66 0.16
127 INT139538 Binding of CD34 and KIT 2 0.39 2.73 0.14
128 INT147727 Phosphorylation of PTK2 Regulation of Positive_regulation of RAC1 1 0.34 0.32 0.14
129 INT95103 TGFBR2 Positive_regulation of CD34 1 0.11 0.61 0.14
130 INT291644 Binding of DST and ESR1 1 0.05 0.84 0.14
131 INT147726 Phosphorylation of PTK2 Regulation of Positive_regulation of PIK3CA 1 0.09 0.32 0.14
132 INT148594 Binding of BCL2 and CD34 1 0.39 1.17 0.13
133 INT32294 ENG Positive_regulation of Trh 1 0.01 0 0.13
134 INT277986 Negative_regulation of Epo Positive_regulation of Localization of Cd34 1 0.08 0.77 0.12
135 INT259629 Binding of Adam17 and Timp3 1 0.01 0.19 0.11
136 INT156836 ETS1 Positive_regulation of Phosphorylation of MAPK7 1 0.14 0 0.1
137 INT210989 Binding of FSCN1 and SP3 1 0.00 0.17 0.1
138 INT156838 MAPK7 Positive_regulation of Phosphorylation of ETS1 1 0.13 0 0.1
139 INT304499 Map2k1 Positive_regulation of Mapk1 1 0.12 0.8 0.1
140 INT118052 Binding of Pecam1 and Cd34 1 0.22 0.51 0.1
141 INT275157 Binding of Stat3 and Rac1 1 0.05 0.71 0.1
142 INT275158 Rac1 Positive_regulation of Stat3 1 0.07 0.72 0.1
143 INT60399 ENG Regulation of Localization of Prl 1 0.04 0.57 0.1
144 INT210991 Binding of FSCN1 and PKDREJ 1 0.00 0.17 0.1
145 INT158011 KLRF1 Positive_regulation of ENG 1 0.03 0.39 0.09
146 INT158012 Binding of ENG and FLT1 1 0.21 0.39 0.09
147 INT299953 Binding of CD34 and FTSJ3 1 0.04 1.07 0.09
148 INT206054 RAC1 Positive_regulation of STAT3 1 0.07 0.11 0.09
149 INT214168 Msx1 Positive_regulation of Gene_expression of DST 1 0.00 0.13 0.09
150 INT178089 Binding of EDNRA and Positive_regulation of PTK2 1 0.09 0.74 0.09
151 INT224531 Positive_regulation of Map2k1 Positive_regulation of Positive_regulation of Ankh 1 0.07 0.54 0.09
152 INT214166 DST Negative_regulation of Gene_expression of Npy 1 0.02 0.07 0.09
153 INT32290 ENG Regulation of Positive_regulation of Trh 1 0.01 0 0.09
154 INT311083 DST Regulation of FOS 1 0.03 0.15 0.08
155 INT348167 Thbs1 Positive_regulation of RAC1 1 0.04 0.71 0.08
156 INT311917 Gene_expression of Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.31 0.08
157 INT353070 ADAM17 Positive_regulation of TNF 1 0.19 1.66 0.08
158 INT355582 VEGFA Regulation of Positive_regulation of PTK2 1 0.05 1.46 0.08
159 INT171709 Rac1 Negative_regulation of Localization of Chrna7 1 0.04 0.75 0.08
160 INT311915 Tgfbr1 Negative_regulation of Gene_expression of Mmp13 1 0.09 0.27 0.06
161 INT209615 Binding of KRT20 and Cd34 1 0.00 1.05 0.06
162 INT25491 TFPI Regulation of Localization of ENG 1 0.27 0.31 0.06
163 INT25490 Binding of ENG and TFPI 1 0.27 0.4 0.06
164 INT135641 Binding of Dst and Ina 1 0.35 0.34 0.06
165 INT209611 Binding of Mme and Cd34 1 0.00 1.05 0.06
166 INT118227 Binding of ACTG2 and CD34 1 0.15 1.17 0.06
167 INT209610 Binding of Cd22 and Cd34 1 0.01 1.05 0.06
168 INT302632 Rac1 Positive_regulation of Gene_expression of Rhog 1 0.37 0.21 0.05
169 INT206087 RAC1 Positive_regulation of Gene_expression of STAT3 1 0.08 0.05 0.05
170 INT346280 Binding of COL5A2 and PTK2 1 0.01 0.1 0.05
171 INT194699 MAP2K1 Positive_regulation of MAPK8 1 0.05 0 0.04
172 INT194703 MAP2K1 Positive_regulation of MAP2K6 1 0.21 0 0.04
173 INT194677 Binding of GADD45A and MAP2K1 1 0.27 0 0.04
174 INT194719 MAP2K1 Positive_regulation of MAPK1 1 0.27 0 0.04
175 INT206073 Negative_regulation of RAC1 Positive_regulation of IL6 1 0.14 0.06 0.04
176 INT32293 ENG Regulation of Positive_regulation of Gnrh1 1 0.00 0 0.04
177 INT206067 Gene_expression of RAC1 Positive_regulation of Positive_regulation of IL6 1 0.16 0.07 0.04
178 INT194701 MAP2K1 Positive_regulation of MAP2K4 1 0.21 0 0.04
179 INT194732 MAP2K1 Positive_regulation of Gene_expression of MAPK1 1 0.27 0 0.04
180 INT32297 ENG Regulation of Positive_regulation of LH 1 0.00 0 0.04
181 INT206068 RAC1 Positive_regulation of IL6 1 0.16 0.06 0.04
182 INT320786 Binding of Eng and Kdr 1 0.04 1.17 0.04
183 INT311082 DST Regulation of MAPK8 1 0.02 0.07 0.04
184 INT194691 MAP2K1 Positive_regulation of MAP2K3 1 0.23 0 0.04
185 INT295479 PRKCA Positive_regulation of MAP2K1 1 0.14 0.35 0.03
186 INT265347 Binding of Ocln and Tgfbr1 1 0.18 0.06 0.03
187 INT265345 Binding of Tgfbr1 and Tjp1 1 0.09 0.06 0.03
188 INT206061 RAC1 Positive_regulation of Positive_regulation of STAT3 1 0.07 0.43 0.03
189 INT194707 RAC1 Positive_regulation of PAK1 1 0.01 0 0.03
190 INT214167 Binding of DST and Pomc 1 0.03 0.22 0.03
191 INT194738 Binding of PAK1 and RAC1 1 0.01 0 0.03
192 INT214171 Binding of DST and Cartpt 1 0.01 0.21 0.03
193 INT269502 Lta Negative_regulation of Map2k1 1 0.17 0.48 0.03
194 INT254511 RAC1 Positive_regulation of Positive_regulation of CYBB 1 0.14 0.39 0.03
195 INT265343 Positive_regulation of Binding of Tgfbr1 and Tjp1 1 0.12 0.06 0.03
196 INT295474 IRF6 Positive_regulation of MAP2K1 1 0.18 0.41 0.03
197 INT265348 Positive_regulation of Binding of Ocln and Tgfbr1 1 0.25 0.06 0.03
198 INT288829 Binding of Rhoa and Rac1 2 0.21 1.88 0
199 INT340614 Binding of ENG and MMP9 1 0.16 0.14 0
200 INT225898 Positive_regulation of RAC1 Positive_regulation of PAK1 1 0.01 0.08 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cell motility. They are ordered first by their pain relevance and then by number of times they were reported in cell motility. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6
2 INT129686 Gene_expression of FSCN1 46 0.15 18.91 34.47
3 INT11764 Positive_regulation of ENG 78 0.61 27.65 33.69
4 INT19396 Regulation of Rac1 66 0.53 37.41 30.01
5 INT10799 Localization of ENG 63 0.78 18.67 27.28
6 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33
7 INT104523 Positive_regulation of FSCN1 14 0.12 10.09 20.08
8 INT104527 Binding of FSCN1 18 0.23 14.75 19.6
9 INT23212 Positive_regulation of Rac1 46 0.55 32.85 15.1
10 INT7674 Regulation of ENG 42 0.30 11.41 14.44
11 INT27627 Binding of Rac1 41 0.41 22.88 13.68
12 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39
13 INT67101 Gene_expression of DST 47 0.54 25.92 9.59
14 INT50055 Negative_regulation of Rac1 36 0.50 19.74 8.98
15 INT49325 Gene_expression of Cd34 102 0.78 82.75 8.97
16 INT109724 Phosphorylation of FSCN1 5 0.07 3.15 8.82
17 INT7673 Negative_regulation of ENG 31 0.42 7.9 8.61
18 INT135443 Phosphorylation of Map2k1 11 0.80 2.44 8.01
19 INT171367 Phosphorylation of Map2k1 31 0.58 32.87 8
20 INT135441 Positive_regulation of Map2k1 15 0.67 6.6 7.87
21 INT38644 Positive_regulation of DST 30 0.53 12.48 6.59
22 INT93137 Negative_regulation of Map2k1 17 0.42 4.51 6.49
23 INT23375 Binding of ENG 17 0.47 6.02 6.46
24 INT130875 Gene_expression of ADAM17 13 0.78 15.46 6.41
25 INT189177 Positive_regulation of Gene_expression of FSCN1 12 0.11 3.77 6.12
26 INT129685 Negative_regulation of FSCN1 7 0.05 3.44 5.69
27 INT69350 Gene_expression of RAC1 23 0.77 12.16 5.54
28 INT135440 Positive_regulation of Phosphorylation of Map2k1 5 0.49 1.32 5.22
29 INT104342 Regulation of FSCN1 4 0.15 3.18 4.84
30 INT104299 Negative_regulation of Adam17 18 0.47 12.03 4.39
31 INT87345 Phosphorylation of PTK2 110 0.82 59.39 4.28
32 INT167174 Negative_regulation of Gene_expression of FSCN1 6 0.06 3.05 4.25
33 INT21681 Positive_regulation of CD34 54 0.66 33.95 4.14
34 INT106065 Negative_regulation of MAP2K1 27 0.57 12.69 3.97
35 INT78619 Positive_regulation of RAC1 27 0.65 10.43 3.75
36 INT11761 Negative_regulation of DST 13 0.42 7.66 3.65
37 INT102076 Regulation of DST 15 0.22 10 3.5
38 INT15844 Positive_regulation of Localization of ENG 7 0.67 4.2 3.47
39 INT121967 Regulation of RAC1 9 0.45 6.14 3.41
40 INT106422 Negative_regulation of Gene_expression of Rac1 4 0.43 3.97 3.41
41 INT67379 Positive_regulation of Cd34 38 0.58 26.18 3.28
42 INT58475 Localization of Rac1 12 0.75 5.94 3.2
43 INT75484 Gene_expression of Tgfbr1 21 0.64 13.36 3.15
44 INT134470 Positive_regulation of Map2k1 74 0.49 46.07 3.02
45 INT32222 Negative_regulation of Gene_expression of ENG 9 0.37 2.23 2.89
46 INT102157 Gene_expression of Adam17 3 0.58 4.17 2.86
47 INT332774 Positive_regulation of Phosphorylation of FSCN1 1 0.02 0.69 2.63
48 INT22071 Positive_regulation of Gene_expression of ENG 13 0.50 5.44 2.62
49 INT65928 Positive_regulation of Gene_expression of Rac1 12 0.42 3.34 2.33
50 INT13997 Regulation of Gene_expression of ENG 11 0.36 3.31 2.31
51 INT12133 Regulation of Localization of ENG 3 0.03 0.57 2.24
52 INT70987 Binding of RAC1 14 0.37 12.14 2.13
53 INT127756 Negative_regulation of Map2k1 10 0.41 6.69 2.04
54 INT32135 Positive_regulation of Positive_regulation of ENG 2 0.02 0.98 1.99
55 INT117980 Regulation of Rac1 10 0.45 3.72 1.88
56 INT117346 Positive_regulation of ADAM17 5 0.50 6.69 1.86
57 INT135444 Regulation of Map2k1 4 0.44 1.15 1.77
58 INT130874 Negative_regulation of Gene_expression of ADAM17 3 0.43 5.03 1.76
59 INT104524 Localization of FSCN1 3 0.13 1.76 1.75
60 INT15845 Negative_regulation of Localization of ENG 3 0.05 0.76 1.71
61 INT116110 Positive_regulation of PTK2 20 0.66 10.53 1.64
62 INT130332 Gene_expression of Adam17 14 0.50 4.84 1.56
63 INT135640 Negative_regulation of Dst 5 0.57 2.25 1.56
64 INT111946 Positive_regulation of Phosphorylation of PTK2 8 0.66 11.5 1.53
65 INT21682 Binding of CD34 18 0.47 13.19 1.47
66 INT104121 Positive_regulation of MAP2K1 8 0.61 4.84 1.41
67 INT58930 Negative_regulation of RAC1 14 0.55 7.55 1.4
68 INT175525 Positive_regulation of Phosphorylation of Map2k1 8 0.33 7.02 1.37
69 INT71782 Gene_expression of MAP2K1 7 0.68 3.17 1.37
70 INT78861 Negative_regulation of Transcription of Adam17 2 0.29 1.4 1.32
71 INT78859 Transcription of Adam17 2 0.47 1.39 1.31
72 INT38645 Negative_regulation of Positive_regulation of DST 3 0.29 1.05 1.29
73 INT32717 Negative_regulation of Regulation of ENG 3 0.00 0.43 1.25
74 INT90938 Gene_expression of Eng 48 0.72 15.76 1.24
75 INT268027 Regulation of Gene_expression of FSCN1 3 0.03 0.64 1.23
76 INT234893 Positive_regulation of Adam17 4 0.38 3.78 1.22
77 INT16013 Gene_expression of Rac1 52 0.75 23.79 1.21
78 INT98062 Regulation of Gene_expression of Rac1 4 0.39 1.41 1.21
79 INT87343 Negative_regulation of Phosphorylation of PTK2 34 0.59 18.38 1.19
80 INT87346 Binding of PTK2 6 0.37 4.03 1.18
81 INT101027 Binding of DST 20 0.41 10.9 1.17
82 INT310164 Negative_regulation of Gene_expression of Tgfbr1 9 0.40 6.11 1.17
83 INT98061 Negative_regulation of Binding of Rac1 3 0.43 2.28 1.13
84 INT51863 Negative_regulation of Negative_regulation of ENG 2 0.04 0.51 1.13
85 INT87342 Regulation of Phosphorylation of PTK2 3 0.59 5.7 1.05
86 INT138287 Gene_expression of Map2k1 69 0.65 46.14 1.02
87 INT132435 Negative_regulation of ADAM17 2 0.50 3.75 1.02
88 INT137675 Binding of Srpx2 5 0.37 0.6 1.01
89 INT67174 Negative_regulation of Rac1 22 0.56 10.72 0.99
90 INT119168 Negative_regulation of Cd34 8 0.37 4.91 0.96
91 INT332775 Regulation of Phosphorylation of FSCN1 1 0.02 0.19 0.95
92 INT81211 Transcription of Rac1 4 0.54 1.05 0.89
93 INT87344 Gene_expression of PTK2 90 0.78 59.03 0.87
94 INT126967 Localization of Cd34 9 0.79 3.69 0.87
95 INT265313 Positive_regulation of Tgfbr1 8 0.66 2.95 0.87
96 INT175904 Localization of RAC1 7 0.41 5.05 0.86
97 INT111943 Negative_regulation of Positive_regulation of RAC1 2 0.46 1.33 0.86
98 INT330097 Positive_regulation of Positive_regulation of Rac1 1 0.37 2.47 0.86
99 INT96188 Binding of Cd34 11 0.31 10.4 0.82
100 INT71778 Positive_regulation of Gene_expression of MAP2K1 2 0.36 0.37 0.81
101 INT264629 Localization of Rac1 8 0.72 5.7 0.79
102 INT111945 Protein_catabolism of RAC1 1 0.31 0.67 0.79
103 INT87341 Regulation of Gene_expression of PTK2 2 0.62 8.34 0.77
104 INT161947 Positive_regulation of TGFBR1 2 0.52 1.6 0.76
105 INT211909 Regulation of Positive_regulation of Map2k1 1 0.21 0.47 0.76
106 INT115596 Regulation of Regulation of Rac1 1 0.36 0.29 0.7
107 INT11763 Positive_regulation of Regulation of ENG 1 0.01 0.97 0.64
108 INT252860 Negative_regulation of Binding of FSCN1 1 0.02 0.85 0.61
109 INT244420 Positive_regulation of Gene_expression of DST 4 0.41 2.05 0.59
110 INT341563 Positive_regulation of ITGB4 1 0.38 2.58 0.59
111 INT94713 Regulation of CD34 11 0.45 8.02 0.58
112 INT128472 Negative_regulation of CD34 7 0.42 3.92 0.58
113 INT147734 Phosphorylation of RAC1 3 0.64 1.33 0.58
114 INT228103 Positive_regulation of Rac1 25 0.67 18.92 0.57
115 INT90939 Positive_regulation of Eng 9 0.64 4.62 0.57
116 INT144922 Gene_expression of TGFBR1 4 0.72 0.19 0.57
117 INT138678 Transcription of ADAM17 1 0.69 4.9 0.56
118 INT104120 Positive_regulation of Positive_regulation of MAP2K1 1 0.49 0 0.54
119 INT16012 Binding of Rac1 17 0.37 6.9 0.53
120 INT127736 Regulation of Gene_expression of RAC1 2 0.27 2 0.53
121 INT196003 Regulation of Cd34 4 0.30 3.38 0.5
122 INT138676 Localization of ADAM17 4 0.73 4.91 0.5
123 INT236915 Binding of Map2k1 2 0.15 1.51 0.49
124 INT292074 Transcription of FSCN1 1 0.04 0.56 0.48
125 INT87819 Localization of CD34 21 0.81 7.69 0.47
126 INT164267 Negative_regulation of Phosphorylation of RAC1 1 0.33 0.96 0.46
127 INT81212 Negative_regulation of Transcription of Rac1 1 0.01 0 0.46
128 INT164266 Positive_regulation of Phosphorylation of RAC1 1 0.39 0.95 0.45
129 INT119251 Positive_regulation of Gene_expression of CD34 12 0.49 5.2 0.44
130 INT87847 Regulation of Positive_regulation of Rac1 2 0.36 1.49 0.43
131 INT214136 Localization of DST 7 0.65 2.59 0.42
132 INT138282 Positive_regulation of Gene_expression of Map2k1 13 0.49 7.46 0.39
133 INT292484 Negative_regulation of TGFBR1 3 0.19 0.75 0.39
134 INT251556 Localization of Adam17 2 0.38 2 0.39
135 INT350671 Gene_expression of Ets1 1 0.10 1.25 0.39
136 INT135638 Binding of Dst 4 0.36 2.76 0.38
137 INT304528 Gene_expression of Map2k1 3 0.58 1.76 0.37
138 INT156860 Gene_expression of ETS1 2 0.30 0.84 0.37
139 INT200744 Regulation of Gene_expression of DST 5 0.20 2.64 0.36
140 INT232153 Regulation of Negative_regulation of Cd34 1 0.05 0.07 0.35
141 INT254816 Negative_regulation of Tgfbr1 20 0.55 9.24 0.34
142 INT124986 Positive_regulation of Localization of Rac1 3 0.50 1.22 0.33
143 INT78862 Negative_regulation of Adam17 3 0.36 1.76 0.32
144 INT304526 Binding of Map2k1 1 0.11 0.6 0.32
145 INT75628 Gene_expression of Dst 4 0.60 0.78 0.31
146 INT112551 Protein_catabolism of Rac1 2 0.66 0.29 0.3
147 INT187284 Positive_regulation of Gene_expression of Adam17 3 0.20 1.32 0.29
148 INT314672 Positive_regulation of Srpx2 1 0.58 0.7 0.29
149 INT116729 Regulation of Localization of Rac1 1 0.01 0.07 0.29
150 INT311881 Regulation of Positive_regulation of Tgfbr1 1 0.22 0.97 0.29
151 INT314670 Positive_regulation of Protein_catabolism of Srpx2 1 0.39 0.7 0.29
152 INT314669 Protein_catabolism of Srpx2 1 0.55 0.69 0.29
153 INT326154 Regulation of ETS1 1 0.07 1.69 0.29
154 INT240205 Regulation of MAP2K1 3 0.26 0.44 0.28
155 INT176492 Positive_regulation of Gene_expression of ETS1 1 0.09 0.84 0.28
156 INT99682 Phosphorylation of Rac1 1 0.54 0.72 0.28
157 INT162873 Negative_regulation of Negative_regulation of Rac1 1 0.34 0.35 0.26
158 INT330090 Regulation of Negative_regulation of Rac1 1 0.36 0.53 0.25
159 INT180101 Phosphorylation of Adam17 3 0.37 0.25 0.24
160 INT119080 Negative_regulation of PTK2 15 0.56 8.88 0.23
161 INT232504 Negative_regulation of Gene_expression of CD34 4 0.38 1.89 0.23
162 INT75626 Positive_regulation of Dst 2 0.50 0.52 0.23
163 INT175506 Regulation of Positive_regulation of Map2k1 2 0.32 1.58 0.23
164 INT330093 Negative_regulation of Positive_regulation of Rac1 1 0.34 0.88 0.23
165 INT78865 Localization of Adam17 1 0.43 0.34 0.23
166 INT304519 Positive_regulation of Gene_expression of Map2k1 1 0.15 0.41 0.22
167 INT282322 Regulation of Binding of DST 1 0.04 0.35 0.22
168 INT87338 Regulation of PTK2 10 0.62 4.75 0.21
169 INT135637 Regulation of Dst 3 0.44 1.03 0.2
170 INT311886 Phosphorylation of Tgfbr1 1 0.40 0.7 0.19
171 INT292483 Negative_regulation of Positive_regulation of PTK2 2 0.41 3.51 0.18
172 INT131558 Protein_catabolism of ENG 1 0.01 0 0.18
173 INT200745 Negative_regulation of Gene_expression of DST 3 0.10 2.75 0.17
174 INT189311 Gene_expression of ITGB4 2 0.41 0.53 0.16
175 INT168055 Regulation of Transcription of Rac1 1 0.36 0.34 0.16
176 INT135706 Negative_regulation of Binding of CD34 1 0.40 1.19 0.16
177 INT138679 Regulation of ADAM17 1 0.19 1.13 0.16
178 INT137457 Positive_regulation of Localization of Cd34 1 0.46 0.55 0.16
179 INT138680 Binding of ADAM17 1 0.36 1.42 0.16
180 INT133599 Positive_regulation of Binding of Rac1 2 0.40 0.4 0.15
181 INT330085 Regulation of Binding of Rac1 1 0.36 0.28 0.15
182 INT147730 Regulation of Positive_regulation of PTK2 1 0.35 0.33 0.15
183 INT254671 Regulation of Map2k1 5 0.43 1.83 0.14
184 INT137682 Positive_regulation of Binding of Srpx2 1 0.38 0 0.14
185 INT265533 Negative_regulation of Phosphorylation of Map2k1 1 0.41 0 0.14
186 INT90940 Binding of Eng 5 0.35 1.92 0.13
187 INT175527 Localization of Map2k1 4 0.31 2.41 0.13
188 INT232508 Regulation of Gene_expression of CD34 4 0.43 2.73 0.13
189 INT282160 Regulation of Binding of RAC1 1 0.18 0.45 0.13
190 INT302662 Negative_regulation of Negative_regulation of TGFBR1 1 0.14 0 0.13
191 INT169349 Regulation of Adam17 1 0.37 0.97 0.13
192 INT75625 Localization of Dst 1 0.75 0.15 0.13
193 INT254673 Positive_regulation of Positive_regulation of Map2k1 3 0.35 1.65 0.11
194 INT138677 Negative_regulation of Transcription of ADAM17 1 0.42 1.18 0.1
195 INT156854 Phosphorylation of ETS1 1 0.24 0 0.1
196 INT26064 Regulation of Positive_regulation of ENG 1 0.01 0.1 0.09
197 INT254819 Regulation of Negative_regulation of Tgfbr1 1 0.15 1.2 0.09
198 INT156847 Negative_regulation of ETS1 1 0.16 0 0.09
199 INT187285 Protein_catabolism of Adam17 1 0.12 0.94 0.09
200 INT90941 Negative_regulation of Eng 1 0.31 0.25 0.09
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