GO:0048872

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Name homeostasis of number of cells
Categary Process
Go Slim No
Go Link GO:0048872
Unique Molecular Interactions 148
Total Molecular Interactions 168
Total Single Events 1704
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for homeostasis of number of cells. They are ordered first by their pain relevance and then by number of times they were reported for homeostasis of number of cells. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
2 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
3 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
4 INT112699 Bid Regulation of Bax 1 0.25 0.51 0.61
5 INT350150 Binding of LPP and ATXN2 1 0.35 1.82 0.54
6 INT41174 Bak1 Regulation of Localization of Prl 1 0.02 0 0.46
7 INT238638 Gopc Negative_regulation of Gene_expression of Bax 1 0.04 0.85 0.45
8 INT327182 Binding of Mpl and Thpo 1 0.41 0.54 0.37
9 INT155061 Stat3 Negative_regulation of Bax 1 0.22 3.71 0.34
10 INT260870 Binding of HLA-E and IL7R 1 0.19 0.5 0.22
11 INT131963 Binding of CAV2 and ATXN2 1 0.04 1.39 0.21
12 INT353285 Prdx2 Regulation of Gene_expression of Col1a2 1 0.02 0.73 0.21
13 INT350152 Binding of ATXN2 and SNRNP70 1 0.13 1.22 0.2
14 INT155063 Csf2 Negative_regulation of Gene_expression of Bax 1 0.27 1.46 0.18
15 INT285026 Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
16 INT285022 Regulation of Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
17 INT155066 Csf2 Negative_regulation of Bax 1 0.12 1.89 0.17
18 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17
19 INT285024 Bcl2 Regulation of Bak1 1 0.09 0.71 0.17
20 INT275461 Binding of Atxn1 and Atxn2 1 0.39 1.1 0.17
21 INT336891 Epo Negative_regulation of Transcription of Bax 1 0.10 0.68 0.16
22 INT194829 Gata3 Positive_regulation of IL13 1 0.01 0.12 0.15
23 INT194835 Gata3 Positive_regulation of IL5 1 0.01 0.12 0.15
24 INT71328 Cacna1a Regulation of Atxn2 1 0.00 0.71 0.15
25 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15
26 INT194833 Binding of IL5 and Gata3 1 0.01 0.12 0.15
27 INT194827 Binding of IL13 and Gata3 1 0.01 0.12 0.15
28 INT273040 Vip Regulation of Bax 1 0.23 1.69 0.13
29 INT273041 Adcyap1 Regulation of Bax 1 0.21 1.69 0.13
30 INT338428 Il4 Positive_regulation of Gata3 1 0.06 0.75 0.13
31 INT226192 Protein_catabolism of Bax Positive_regulation of Gtf3a 1 0.00 0.53 0.12
32 INT285030 Binding of Bax and Slc25a4 1 0.03 0.84 0.11
33 INT204300 Bcl2 Negative_regulation of Positive_regulation of Bak1 1 0.02 1.13 0.09
34 INT296034 FOXP3 Negative_regulation of Gene_expression of IL7R 1 0.10 0.63 0.08
35 INT204301 Positive_regulation of Hrk Positive_regulation of Positive_regulation of Bak1 1 0.00 1.17 0.07
36 INT285025 Bnip3 Positive_regulation of Bak1 1 0.11 0.78 0.07
37 INT285032 Bnip3 Positive_regulation of Bax 1 0.28 0.77 0.07
38 INT340401 Positive_regulation of Bax Positive_regulation of Binding of Hrk 1 0.01 0.79 0.07
39 INT340395 Binding of Bax and Tg(CAG-EGFP)D4Nagy 1 0.02 0.43 0.07
40 INT273288 Psen1 Regulation of Prdx2 1 0.01 0.7 0.06
41 INT353284 Prdx2 Negative_regulation of Gene_expression of Smad2 1 0.16 0.07 0.05
42 INT339979 Binding of PRDX2 and HDAC9 1 0.02 0.16 0.05
43 INT143993 Prdx2 Positive_regulation of Atp13a4 1 0.00 0 0.05
44 INT280738 Mpl Positive_regulation of gr 1 0.01 0 0.05
45 INT106487 Gene_expression of CD177 Negative_regulation of Gene_expression of Mpl 1 0.02 1.74 0.04
46 INT280616 Binding of Neu2 and Mpl 1 0.00 0.12 0.04
47 INT340394 Binding of Bax and Bbc3 1 0.01 0.36 0.04
48 INT204298 Bid Positive_regulation of Binding of Bak1 1 0.05 0.57 0.04
49 INT353289 Prdx2 Negative_regulation of Positive_regulation of Smad2 1 0.18 0.17 0.04
50 INT353293 Prdx2 Negative_regulation of Localization of Smad2 1 0.16 0 0.04
51 INT172902 Binding of Bax and Bcl2 5 0.30 3.19 0.03
52 INT353287 Prdx2 Positive_regulation of Phosphorylation of Smad7 1 0.22 0.06 0.03
53 INT297737 Cbr1 Positive_regulation of Bax 1 0.06 0.53 0.03
54 INT353291 Prdx2 Positive_regulation of Smad7 1 0.31 0.06 0.03
55 INT224682 Mcl1 Regulation of Bak1 1 0.01 1.09 0.03
56 INT353286 Prdx2 Positive_regulation of Phosphorylation of Smad2 1 0.24 0.06 0.03
57 INT333259 Bcl2 Regulation of Bax 1 0.03 0.32 0.03
58 INT224689 Binding of Bak1 and Mcl1 1 0.01 1.09 0.03
59 INT224676 Binding of Bax and Mcl1 1 0.01 1.09 0.03
60 INT333249 Cxcl12 Positive_regulation of Positive_regulation of Bak1 1 0.30 0.32 0.03
61 INT353283 Prdx2 Positive_regulation of Phosphorylation of Tgif1 1 0.10 0.06 0.03
62 INT224690 Mcl1 Regulation of Bax 1 0.00 1.09 0.03
63 INT333262 Bcl2 Regulation of Bak1 1 0.04 0.31 0.03
64 INT353292 Prdx2 Positive_regulation of Tgif1 1 0.10 0.06 0.03
65 INT341376 Sod2 Regulation of Bax 1 0.09 0.99 0.03
66 INT283013 Binding of Bak1 and Bcl2 4 0.06 1.03 0
67 INT172906 Binding of Bax and Bcl2l1 2 0.16 2.03 0
68 INT287892 PRDX2 Positive_regulation of HNF4A 1 0.00 0.52 0
69 INT285029 Binding of Bax and Bcl2l1 1 0.25 0.1 0
70 INT330047 Binding of Bax and Bcl2l11 1 0.13 0.62 0
71 INT191058 Binding of Bcl2 and Positive_regulation of Gene_expression of Bax 1 0.21 0.49 0
72 INT333258 Gene_expression of Cxcl12 Positive_regulation of Positive_regulation of Bak1 1 0.15 0.55 0
73 INT322658 Binding of Bak1 and Prdm8 1 0.02 0.89 0
74 INT242483 Negative_regulation of Ciapin1 Negative_regulation of Positive_regulation of Bax 1 0.17 1.76 0
75 INT136914 Mapk8 Positive_regulation of Localization of Bax 1 0.51 0.12 0
76 INT322664 Prdm8 Positive_regulation of Gene_expression of Bax 1 0.01 1.1 0
77 INT285028 Binding of Bcl2 and Bax 1 0.32 0.1 0
78 INT280613 Fig4 Regulation of Gene_expression of Mpl 1 0.03 0 0
79 INT229821 Fos Positive_regulation of Bax 1 0.15 0.27 0
80 INT322668 Prdm8 Positive_regulation of Gene_expression of Bak1 1 0.02 1.1 0
81 INT309517 Binding of Bax and Xrcc6 1 0.15 0.5 0
82 INT201761 BIK Positive_regulation of Positive_regulation of Bax 1 0.01 0.43 0
83 INT330052 Binding of Bax and Bid 1 0.15 0.62 0
84 INT322662 Binding of Bax and Pbrm1 1 0.08 0.9 0
85 INT172908 Binding of Bad and Bax 1 0.01 1.34 0
86 INT330057 Bid Positive_regulation of Bax 1 0.19 0.62 0
87 INT283002 Binding of Bak1 and Mgst1 1 0.01 0.24 0
88 INT313426 Positive_regulation of Ppp2ca Positive_regulation of Bax 1 0.46 0.36 0
89 INT261840 Binding of Mtap7 and Trpv4 1 0.05 0.12 0
90 INT267252 Bax Regulation of Bak1 1 0.05 1.09 0
91 INT201765 Binding of BCL2L1 and Bax 1 0.00 0.28 0
92 INT352151 Binding of Bak1 and Gopc 1 0.02 0.26 0
93 INT201763 BID Positive_regulation of Positive_regulation of Bax 1 0.01 0.43 0
94 INT242476 Negative_regulation of Ciapin1 Positive_regulation of Bax 1 0.19 1.29 0
95 INT322670 Prdm8 Positive_regulation of Bax 1 0.01 1.1 0
96 INT275753 xn Regulation of Bax 1 0.05 1.31 0
97 INT333681 Trp53 Regulation of Negative_regulation of Bax 1 0.15 1.17 0
98 INT334718 Binding of NOS1 and Bax 1 0.02 0.87 0
99 INT330054 Bcl2l11 Positive_regulation of Bax 1 0.25 0.62 0
100 INT322666 Binding of Bak1 and Pbrm1 1 0.20 0.9 0
101 INT254090 EPO Negative_regulation of Gene_expression of Bax 1 0.10 0.63 0
102 INT340400 Binding of Bax and Mom6 1 0.04 0.28 0
103 INT275746 Binding of xn and Bax 1 0.05 2.57 0
104 INT322663 Prdm8 Positive_regulation of Bak1 1 0.01 1.1 0
105 INT340399 Binding of Bak1 and Bax 1 0.12 0.91 0
106 INT309518 Negative_regulation of Binding of Bax and Xrcc6 1 0.16 0.25 0
107 INT201768 BCL2L11 Positive_regulation of Positive_regulation of Bax 1 0.00 0.43 0
108 INT201743 Bad Positive_regulation of Positive_regulation of Bax 1 0.00 0.43 0
109 INT136915 RYBP Positive_regulation of Localization of Bax 1 0.01 0.12 0
110 INT322660 Binding of Bax and Prdm8 1 0.01 0.89 0
111 INT100425 Bax Regulation of Pcbd1 1 0.06 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for homeostasis of number of cells. They are ordered first by their pain relevance and then by number of times they were reported in homeostasis of number of cells. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
2 INT106484 Gene_expression of Mpl 7 0.78 20.2 16.48
3 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36
4 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51
5 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28
6 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33
7 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41
8 INT145929 Regulation of Bax 20 0.60 18.12 5.35
9 INT109513 Positive_regulation of Gene_expression of Bax 37 0.67 29.52 5.06
10 INT99504 Negative_regulation of Bax 19 0.56 8.89 4.44
11 INT116011 Positive_regulation of Gata3 5 0.31 3.17 4.21
12 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12
13 INT123752 Regulation of Bax 19 0.60 16.45 4
14 INT112692 Localization of Bax 31 0.80 20.97 3.98
15 INT202419 Positive_regulation of Gene_expression of Gata3 6 0.52 5.47 2.6
16 INT102146 Phosphorylation of Bax 4 0.66 3.48 2.35
17 INT327172 Regulation of Gene_expression of Mpl 1 0.62 2.32 2.32
18 INT154970 Localization of Bax 15 0.74 11.12 2.11
19 INT108250 Regulation of Prdx2 5 0.25 2.02 2.08
20 INT98836 Transcription of Bax 6 0.69 5.04 1.96
21 INT134442 Transcription of Bax 14 0.67 7.6 1.9
22 INT135540 Negative_regulation of Bax 16 0.48 11.8 1.89
23 INT134443 Binding of Bax 10 0.47 5.62 1.84
24 INT327178 Transcription of Mpl 1 0.72 4.16 1.81
25 INT104883 Positive_regulation of Positive_regulation of Bax 4 0.45 4.05 1.74
26 INT146785 Positive_regulation of Localization of Bax 7 0.69 6.16 1.47
27 INT116014 Transcription of Gata3 4 0.63 2.24 1.46
28 INT109512 Negative_regulation of Gene_expression of Bax 12 0.42 8.04 1.44
29 INT116015 Regulation of Gata3 3 0.22 1.41 1.42
30 INT116008 Binding of Gata3 2 0.34 1.37 1.41
31 INT108249 Negative_regulation of Prdx2 3 0.32 1.85 1.36
32 INT112695 Negative_regulation of Protein_catabolism of Bax 3 0.36 1.72 1.3
33 INT181961 Gene_expression of IL7R 10 0.75 3.9 1.29
34 INT116016 Positive_regulation of Positive_regulation of Gata3 2 0.21 0.5 1.28
35 INT154969 Positive_regulation of Localization of Bax 4 0.64 3.42 1.27
36 INT235157 Gene_expression of Atxn2 3 0.68 6.74 1.23
37 INT460 Negative_regulation of Atxn2 4 0.43 0.85 1.21
38 INT112693 Protein_catabolism of Bax 5 0.74 3.17 1.2
39 INT141189 Negative_regulation of Transcription of Bax 1 0.41 1.42 1.14
40 INT93094 Gene_expression of Bak1 13 0.52 13.94 1.02
41 INT350157 Binding of ATXN2 1 0.33 3.53 1.02
42 INT175507 Regulation of Gene_expression of Bax 13 0.50 10.91 0.95
43 INT108243 Positive_regulation of Prdx2 3 0.34 0.85 0.95
44 INT106746 Gene_expression of Mtap7 1 0.39 2.09 0.95
45 INT135542 Positive_regulation of Bak1 17 0.43 16.12 0.88
46 INT144697 Regulation of Gene_expression of Bax 8 0.37 9.5 0.81
47 INT14040 Binding of Bak1 2 0.30 0.55 0.72
48 INT116012 Regulation of Positive_regulation of Gata3 1 0.20 0.07 0.71
49 INT116006 Positive_regulation of Transcription of Gata3 1 0.21 0.07 0.7
50 INT116010 Positive_regulation of Binding of Gata3 1 0.31 0.07 0.7
51 INT14041 Regulation of Binding of Bak1 1 0.23 0 0.68
52 INT204290 Positive_regulation of Bak1 3 0.22 5.19 0.66
53 INT327176 Positive_regulation of Gene_expression of Mpl 1 0.50 0.14 0.66
54 INT193672 Gene_expression of Prdx2 3 0.50 2.75 0.64
55 INT202416 Negative_regulation of Gata3 2 0.32 1.17 0.64
56 INT290660 Negative_regulation of Gene_expression of Gata3 1 0.25 1.52 0.6
57 INT285007 Regulation of Bak1 1 0.20 3.46 0.56
58 INT275454 Positive_regulation of Atxn2 1 0.50 1.37 0.53
59 INT176242 Binding of Bax 10 0.42 10.18 0.52
60 INT327179 Regulation of Mpl 1 0.62 1.03 0.52
61 INT492 Binding of Atxn2 3 0.48 1.26 0.51
62 INT135541 Negative_regulation of Bak1 6 0.30 4.52 0.49
63 INT102108 Protein_catabolism of Bax 8 0.64 5.69 0.48
64 INT134446 Positive_regulation of Binding of Bax 1 0.49 0.72 0.48
65 INT327175 Localization of Mpl 1 0.75 0 0.43
66 INT152059 Regulation of Transcription of Bax 1 0.26 0.07 0.42
67 INT30733 Localization of Atxn2 4 0.55 0.83 0.41
68 INT98419 Positive_regulation of Mtap7 3 0.38 2.66 0.41
69 INT150946 Negative_regulation of Positive_regulation of Bak1 2 0.29 3.02 0.4
70 INT135802 Positive_regulation of Negative_regulation of Bax 2 0.41 0.57 0.4
71 INT327169 Positive_regulation of Transcription of Mpl 1 0.50 1.81 0.39
72 INT260878 Binding of IL7R 1 0.33 0.87 0.35
73 INT204069 Negative_regulation of Positive_regulation of Bax 5 0.31 3.08 0.34
74 INT169538 Negative_regulation of Localization of Bax 3 0.49 1.41 0.34
75 INT280721 Regulation of Mpl 1 0.18 0 0.34
76 INT184482 Positive_regulation of Positive_regulation of Bax 5 0.41 4.7 0.33
77 INT172216 Binding of Bak1 5 0.25 8.48 0.33
78 INT221191 Negative_regulation of Localization of Bax 4 0.38 2.85 0.33
79 INT93093 Regulation of Gene_expression of Bak1 3 0.30 2.09 0.32
80 INT140379 Positive_regulation of Gene_expression of Bak1 4 0.27 2.27 0.31
81 INT229853 Gene_expression of Bak1 2 0.25 2.04 0.29
82 INT327173 Negative_regulation of Transcription of Mpl 1 0.43 0.87 0.29
83 INT327174 Positive_regulation of Mpl 1 0.47 0.57 0.29
84 INT106483 Negative_regulation of Gene_expression of Mpl 6 0.43 5.87 0.27
85 INT102111 Positive_regulation of Protein_catabolism of Bax 2 0.45 1.14 0.27
86 INT150947 Positive_regulation of Positive_regulation of Bak1 1 0.05 0.6 0.25
87 INT260876 Negative_regulation of IL7R 1 0.29 0.47 0.24
88 INT135543 Negative_regulation of Positive_regulation of Bax 5 0.30 6.4 0.23
89 INT143991 Gene_expression of Prdx2 5 0.61 1.54 0.22
90 INT327181 Negative_regulation of Mpl 1 0.43 1.74 0.21
91 INT161959 Gene_expression of PRDX2 2 0.65 1.38 0.2
92 INT282088 Localization of Bak1 6 0.54 3.78 0.19
93 INT327177 Binding of Mpl 1 0.31 0.79 0.18
94 INT353278 Binding of Prdx2 1 0.21 0.05 0.18
95 INT300463 Regulation of Regulation of Bax 1 0.29 1.33 0.18
96 INT353270 Regulation of Binding of Prdx2 1 0.25 0.05 0.18
97 INT491 Positive_regulation of Binding of Atxn2 1 0.35 0.08 0.17
98 INT353274 Transcription of Prdx2 1 0.39 0.51 0.16
99 INT353264 Negative_regulation of Negative_regulation of Prdx2 1 0.24 0.45 0.15
100 INT285005 Negative_regulation of Bak1 1 0.14 0.16 0.13
101 INT194746 Phosphorylation of Gata3 1 0.10 0.08 0.12
102 INT336888 Negative_regulation of Transcription of Bax 1 0.07 0.68 0.11
103 INT280653 Positive_regulation of Mpl 3 0.26 0 0.1
104 INT275455 Negative_regulation of Gene_expression of Atxn2 1 0.43 1.07 0.1
105 INT193676 Positive_regulation of Gene_expression of Prdx2 2 0.06 1.31 0.09
106 INT304137 Regulation of Localization of Bax 2 0.24 1.7 0.09
107 INT280632 Localization of Mpl 1 0.32 0.25 0.09
108 INT280651 Binding of Mpl 4 0.17 0.12 0.07
109 INT285012 Positive_regulation of Positive_regulation of Bak1 1 0.16 0.77 0.07
110 INT322649 Positive_regulation of Localization of Bak1 1 0.47 1.04 0.07
111 INT349640 Transcription of IL7R 1 0.26 0 0.07
112 INT307466 Positive_regulation of Phosphorylation of Bax 1 0.15 0.76 0.07
113 INT285008 Negative_regulation of Regulation of Bak1 1 0.14 0.87 0.07
114 INT349637 Positive_regulation of Transcription of IL7R 1 0.19 0 0.07
115 INT41372 Regulation of Atxn2 1 0.35 0 0.06
116 INT333214 Regulation of Bak1 1 0.18 1.1 0.06
117 INT268304 Negative_regulation of Gene_expression of Bak1 3 0.28 1.95 0.05
118 INT268622 Regulation of Negative_regulation of Bax 1 0.12 0.81 0.05
119 INT309494 Negative_regulation of Binding of Bax 2 0.38 1.31 0.04
120 INT340387 Regulation of Positive_regulation of Bax 1 0.27 0.61 0.04
121 INT340756 Positive_regulation of PRDX2 1 0.02 1.23 0.04
122 INT340390 Regulation of Binding of Bax 1 0.54 0.59 0.04
123 INT123525 Phosphorylation of Bax 3 0.41 1.18 0.03
124 INT309246 Localization of ATXN2 1 0.10 1.45 0.03
125 INT176247 Positive_regulation of Phosphorylation of Bax 1 0.12 0.42 0.03
126 INT143990 Regulation of Prdx2 1 0.22 0 0.03
127 INT280712 Negative_regulation of Mpl 1 0.17 0.05 0.03
128 INT206742 Negative_regulation of PRDX2 5 0.04 5.04 0
129 INT280647 Gene_expression of Mpl 2 0.30 0 0
130 INT94755 Binding of Mtap7 1 0.31 0 0
131 INT280706 Positive_regulation of Gene_expression of Mpl 1 0.20 0 0
132 INT330041 Positive_regulation of Regulation of Bax 1 0.29 1.63 0
133 INT333213 Regulation of Transcription of Bax 1 0.11 0.14 0
134 INT333223 Phosphorylation of Bak1 1 0.32 0.69 0
135 INT249358 Gene_expression of ATXN2 1 0.37 3.59 0
136 INT333207 Regulation of Transcription of Bak1 1 0.18 0.15 0
137 INT333212 Transcription of Bak1 1 0.27 0.15 0
138 INT280672 Positive_regulation of Binding of Mpl 1 0.23 0 0
139 INT235147 Negative_regulation of Localization of Atxn2 1 0.31 0.46 0
140 INT322640 Positive_regulation of Binding of Bax 1 0.12 0.88 0
141 INT339996 Positive_regulation of Negative_regulation of PRDX2 1 0.05 1.27 0
142 INT327171 Phosphorylation of Mpl 1 0.82 0.09 0
143 INT234056 Positive_regulation of Transcription of Bax 1 0.35 0.36 0
144 INT92060 Localization of Mtap7 1 0.22 0.07 0
145 INT92061 Phosphorylation of Mtap7 1 0.20 0.07 0
146 INT285015 Transcription of Bak1 1 0.22 0.09 0
147 INT285001 Positive_regulation of Transcription of Bak1 1 0.16 0.09 0
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