GO:0050178

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Name phenylpyruvate tautomerase activity
Categary Function
Go Slim No
Go Link GO:0050178
Unique Molecular Interactions 98
Total Molecular Interactions 200
Total Single Events 1165
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for phenylpyruvate tautomerase activity. They are ordered first by their pain relevance and then by number of times they were reported for phenylpyruvate tautomerase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
2 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
3 INT203149 Binding of Mif and Osm 1 0.02 2.93 1.78
4 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
5 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
6 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
7 INT40636 Mif Negative_regulation of Pomc 1 0.25 0.07 0.9
8 INT253992 Cxcl12 Positive_regulation of Mif 1 0.46 1.31 0.88
9 INT203148 Mif Positive_regulation of Gene_expression of S100a8 1 0.00 1.56 0.87
10 INT40703 Mif Negative_regulation of Negative_regulation of POMC 1 0.24 0.49 0.7
11 INT253994 Cyp3a23/3a1 Positive_regulation of Localization of Mif 1 0.09 0.96 0.69
12 INT164990 Mif Positive_regulation of Gene_expression of Grina 1 0.24 0.53 0.6
13 INT195773 Binding of Cd74 and Mif 2 0.25 2.78 0.55
14 INT254197 Mif Regulation of Ptgs2 1 0.02 1.08 0.55
15 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
16 INT195769 MIF Regulation of Gene_expression of TP53I11 1 0.19 1.24 0.47
17 INT253997 Binding of Cd200r1 and Mif 1 0.03 1.02 0.46
18 INT195774 Binding of MIF and Cd74 1 0.02 1.15 0.46
19 INT355571 MIF Positive_regulation of IL8 1 0.04 1.05 0.44
20 INT355568 MIF Positive_regulation of IL6 1 0.05 1.05 0.44
21 INT121364 ZNF398 Negative_regulation of Transcription of MIF 1 0.00 0.9 0.43
22 INT121378 Fancl Positive_regulation of MIF 1 0.01 0.92 0.42
23 INT121365 ZNF398 Negative_regulation of Gene_expression of MIF 1 0.00 0.73 0.38
24 INT355570 MIF Positive_regulation of Gene_expression of IL8 1 0.07 1.11 0.36
25 INT32212 POMC Regulation of Gene_expression of Mif 1 0.00 1.01 0.35
26 INT72953 Mif Positive_regulation of Localization of Prl 1 0.42 0 0.34
27 INT353333 Positive_regulation of F2r Positive_regulation of Localization of Mif 1 0.46 0.26 0.32
28 INT72951 Mif Regulation of Prl 1 0.41 0 0.32
29 INT353334 F2r Positive_regulation of Mif 1 0.68 0 0.32
30 INT353335 F2r Regulation of Positive_regulation of Mif 1 0.27 0.11 0.31
31 INT337085 Binding of Cxcr4 and Mif 1 0.21 1.89 0.3
32 INT353336 F2r Regulation of Localization of Mif 1 0.23 0.24 0.28
33 INT72952 Mif Regulation of Localization of Prl 1 0.28 0 0.27
34 INT254000 Regulation of Binding of Cxcr4 and Mif 1 0.29 0.56 0.27
35 INT353330 F2r Positive_regulation of Positive_regulation of Mif 1 0.46 0 0.26
36 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25
37 INT355567 IRF6 Positive_regulation of MIF 1 0.01 0.29 0.25
38 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25
39 INT198649 Binding of HIF1A and MIF 1 0.01 1.53 0.18
40 INT324874 Positive_regulation of Tlr2 Positive_regulation of Gene_expression of Mif 1 0.05 0.66 0.15
41 INT324860 Tlr2 Positive_regulation of Gene_expression of Mif 1 0.05 0.66 0.15
42 INT195770 Binding of CPB1 and MIF 1 0.01 0.47 0.15
43 INT254002 Binding of Cyp3a23/3a1 and Positive_regulation of Gene_expression of Mif 1 0.08 0.56 0.13
44 INT222425 Mif Regulation of Tlr4 1 0.01 0.24 0.09
45 INT337090 Mif Positive_regulation of Gene_expression of Mapk1 1 0.10 1.11 0.08
46 INT337087 Negative_regulation of Binding of Mif and Cops5 1 0.13 1.64 0.08
47 INT222514 Mif Regulation of Localization of Il6 1 0.04 0.23 0.08
48 INT337088 Binding of Mif and Cops5 1 0.12 1.63 0.08
49 INT337084 Negative_regulation of Binding of Cd74 and Mif 1 0.29 1.64 0.08
50 INT353341 F2r Positive_regulation of Negative_regulation of Mif 1 0.49 0 0.05
51 INT121545 Mif Negative_regulation of Regulation of Ptgs2 1 0.13 0.15 0
52 INT127731 Binding of A2m and Mif 1 0.19 0 0
53 INT253993 Positive_regulation of Binding of Cxcr4 and Mif 1 0.50 0 0
54 INT127732 Binding of Mif and Ilf3 1 0.10 0 0
55 INT353337 F2r Positive_regulation of Gene_expression of Mif 1 0.46 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for phenylpyruvate tautomerase activity. They are ordered first by their pain relevance and then by number of times they were reported in phenylpyruvate tautomerase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT116737 Localization of Mif 63 0.81 52.97 28.11
2 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28
3 INT116736 Positive_regulation of Mif 40 0.70 31.93 15.37
4 INT2385 Gene_expression of MIF 57 0.68 40.74 12.78
5 INT72949 Binding of Mif 31 0.46 23.12 11.65
6 INT117553 Regulation of MIF 10 0.56 12.76 8.67
7 INT32210 Gene_expression of Mif 13 0.75 28.48 7.79
8 INT517 Regulation of Mif 16 0.62 5.43 6.55
9 INT121370 Positive_regulation of MIF 22 0.70 17.79 6.08
10 INT516 Negative_regulation of Mif 13 0.59 6.69 6.08
11 INT83442 Negative_regulation of MIF 18 0.57 9.51 5.12
12 INT174339 Positive_regulation of Localization of Mif 7 0.61 8.27 4.95
13 INT121372 Positive_regulation of Gene_expression of MIF 17 0.60 14.78 4.73
14 INT116738 Positive_regulation of Gene_expression of Mif 14 0.68 10.99 3.8
15 INT130226 Positive_regulation of Gene_expression of Mif 4 0.58 15.75 3.03
16 INT163290 Binding of MIF 9 0.31 7.57 2.8
17 INT203137 Binding of Mif 6 0.31 9.46 2.71
18 INT120011 Localization of MIF 6 0.58 5.72 2.6
19 INT40748 Negative_regulation of Mif 6 0.56 8.33 2.46
20 INT103304 Positive_regulation of Mif 6 0.48 8.66 2.05
21 INT44149 Regulation of Gene_expression of Mif 6 0.54 2.45 1.63
22 INT353326 Negative_regulation of Localization of Mif 1 0.45 1.28 1.59
23 INT253987 Regulation of Localization of Mif 3 0.43 1.65 1.27
24 INT41418 Regulation of Mif 2 0.40 3.86 1.24
25 INT121368 Transcription of Mif 5 0.72 2.71 1.15
26 INT121375 Transcription of MIF 4 0.62 2.85 1.1
27 INT102827 Protein_catabolism of Mif 1 0.33 0 1.06
28 INT121369 Negative_regulation of Gene_expression of MIF 3 0.50 2.48 0.92
29 INT121376 Negative_regulation of Transcription of MIF 3 0.37 2.26 0.87
30 INT353328 Regulation of Positive_regulation of Mif 1 0.40 0.89 0.81
31 INT2108 Localization of Mif 5 0.77 2.7 0.73
32 INT32209 Regulation of Gene_expression of Mif 3 0.59 3.41 0.66
33 INT130229 Regulation of Negative_regulation of Mif 1 0.39 1.36 0.66
34 INT353322 Negative_regulation of Positive_regulation of Mif 1 0.38 0.35 0.66
35 INT44148 Negative_regulation of Gene_expression of Mif 6 0.41 0.95 0.64
36 INT337079 Negative_regulation of Gene_expression of Mif 1 0.41 4.17 0.51
37 INT116735 Positive_regulation of Positive_regulation of Mif 1 0.70 0.61 0.38
38 INT253977 Positive_regulation of Binding of Mif 1 0.48 0.97 0.32
39 INT121374 Regulation of Gene_expression of MIF 2 0.39 1.01 0.29
40 INT121366 Regulation of Transcription of Mif 1 0.02 0.61 0.24
41 INT121367 Negative_regulation of Transcription of Mif 1 0.02 0.59 0.24
42 INT337077 Positive_regulation of Localization of Mif 1 0.58 0.96 0.21
43 INT337076 Positive_regulation of Negative_regulation of Mif 1 0.48 1.44 0.12
44 INT174340 Protein_catabolism of Mif 1 0.89 0.09 0.04
45 INT353329 Positive_regulation of Regulation of Mif 1 0.36 0 0
46 INT337082 Phosphorylation of Mif 1 0.68 0.97 0
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