GO:0050427

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Name 3'-phosphoadenosine 5'-phosphosulfate metabolic process
Categary Process
Go Slim No
Go Link GO:0050427
Unique Molecular Interactions 46
Total Molecular Interactions 63
Total Single Events 401
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for 3'-phosphoadenosine 5'-phosphosulfate metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for 3'-phosphoadenosine 5'-phosphosulfate metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT107602 Binding of OPLL and Enpp1 1 0.15 1.12 0.76
2 INT225775 Enpp1 Positive_regulation of Ppi-rs 1 0.06 2.49 0.44
3 INT225776 Enpp1 Positive_regulation of Positive_regulation of Ppi-rs 1 0.08 1.67 0.28
4 INT225784 Il1 Negative_regulation of Gene_expression of Enpp1 1 0.08 0.99 0.28
5 INT319971 App Regulation of Enpp1 1 0.02 0.72 0.21
6 INT278609 PPARA Positive_regulation of Gene_expression of SULT2A1 1 0.33 0 0.17
7 INT319974 App Negative_regulation of Enpp1 1 0.02 0.58 0.16
8 INT118257 Binding of ENPP1 and SUGT1 1 0.00 0.87 0.16
9 INT278614 NR1I2 Regulation of Gene_expression of SULT2A1 1 0.11 0.11 0.15
10 INT319972 App Negative_regulation of Gene_expression of Enpp1 1 0.02 1.87 0.15
11 INT225783 Enpp1 Regulation of Ppi-rs 1 0.07 0.68 0.13
12 INT238036 Binding of ENPP1 and OPLL 1 0.27 0.66 0.12
13 INT278607 SULT2A1 Positive_regulation of Binding of PPARA 1 0.24 0 0.11
14 INT225805 Binding of SNRNP70 and Enpp1 1 0.42 1.43 0.09
15 INT278611 Binding of CASR and SULT2A1 1 0.03 0 0.07
16 INT278602 Binding of SULT2A1 and NR1I3 1 0.04 0 0.07
17 INT278604 GSR Regulation of Gene_expression of SULT2A1 1 0.02 0.05 0.07
18 INT278613 NR3C1 Regulation of Gene_expression of SULT2A1 1 0.02 0.05 0.07
19 INT278601 NR1I2 Negative_regulation of Gene_expression of SULT2A1 1 0.10 0 0.06
20 INT278606 CASR Regulation of SULT2A1 1 0.04 0 0.05
21 INT278612 NR1I2 Regulation of SULT2A1 1 0.13 0 0.05
22 INT225790 Il1 Regulation of Gene_expression of Enpp1 1 0.07 0.43 0.05
23 INT278603 NR1I2 Positive_regulation of Transcription of SULT2A1 1 0.12 0 0.05
24 INT338988 SULT2A1 Positive_regulation of PPARA 1 0.00 0.42 0.05
25 INT225808 SNRNP70 Regulation of Enpp1 1 0.30 0.71 0.04
26 INT247768 Fcer2a Positive_regulation of Enpp1 1 0.00 0.29 0.04
27 INT225801 Binding of Enpp1 and Npp 1 0.17 0.46 0.04
28 INT225800 Binding of Insr and Enpp1 1 0.05 0.67 0.04
29 INT225802 Binding of Enpp1 and Ppi-rs 1 0.04 1 0.03
30 INT301408 Positive_regulation of Binding of Enpp1 and Twist1 1 0.06 0.18 0.03
31 INT206429 Binding of PRCP and SULT1B1 1 0.16 0.14 0.03
32 INT206428 Binding of SULT1B1 and ASAP1 1 0.28 0.13 0.03
33 INT301406 Binding of Enpp1 and Twist1 1 0.04 0.18 0.03
34 INT206426 Binding of SULT4A1 and ASAP1 1 0.41 0 0
35 INT206425 Binding of SULT1C2 and ASAP1 1 0.30 0 0
36 INT169056 Nfe2l2 Regulation of SULT1A2 1 0.00 0.17 0
37 INT122293 Binding of SULT1A1 and SULT1A3 1 0.37 0 0
38 INT122291 Binding of SULT1E1 and SULT1A3 1 0.33 0 0
39 INT206419 SULT4A1 Positive_regulation of Binding of ASAP1 1 0.43 0 0
40 INT301401 Binding of Enpp1 and Enpp2 1 0.23 0.54 0
41 INT225782 Tnfrsf11b Regulation of Enpp1 1 0.12 0.74 0
42 INT169055 Atf2 Regulation of SULT1A2 1 0.00 0.17 0
43 INT122295 Binding of SULT1E1 and SULT1A1 1 0.36 0 0
44 INT206420 Binding of PRCP and SULT1C2 1 0.19 0 0
45 INT206423 ASAP1 Positive_regulation of SULT4A1 1 0.59 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for 3'-phosphoadenosine 5'-phosphosulfate metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in 3'-phosphoadenosine 5'-phosphosulfate metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT8021 Gene_expression of Enpp1 43 0.78 31.46 10.8
2 INT83745 Gene_expression of SULT2A1 34 0.59 15.96 6.66
3 INT224530 Positive_regulation of Enpp1 12 0.70 7.03 5.82
4 INT170182 Negative_regulation of SULT2A1 14 0.34 11.47 3.63
5 INT68445 Gene_expression of ENPP1 10 0.70 10.8 3.3
6 INT207851 Regulation of Enpp1 5 0.45 4.42 2.96
7 INT61231 Gene_expression of SULT1A1 14 0.75 3.01 2.76
8 INT107597 Binding of Enpp1 5 0.37 3.35 2.23
9 INT83744 Gene_expression of SULT1E1 9 0.75 3.12 2.07
10 INT170185 Localization of SULT2A1 4 0.47 4.65 2
11 INT316778 Positive_regulation of Gene_expression of ENPP1 1 0.62 7.2 1.97
12 INT224529 Positive_regulation of Gene_expression of Enpp1 15 0.70 12.75 1.81
13 INT21822 Regulation of SULT1A1 3 0.62 0 1.75
14 INT170181 Regulation of SULT2A1 4 0.26 5.15 1.56
15 INT332460 Regulation of Binding of Enpp1 1 0.05 0.78 1.5
16 INT107599 Negative_regulation of Enpp1 8 0.51 6.02 1.24
17 INT37171 Negative_regulation of SULT1A1 6 0.55 0.18 1.2
18 INT118258 Positive_regulation of ENPP1 3 0.62 4.26 1.16
19 INT83743 Gene_expression of SULT1B1 7 0.76 0.93 0.71
20 INT35098 Localization of Enpp1 4 0.75 0.81 0.67
21 INT278674 Positive_regulation of Gene_expression of SULT2A1 9 0.29 2.04 0.63
22 INT10226 Negative_regulation of SULT1E1 10 0.58 0.57 0.6
23 INT170183 Regulation of Gene_expression of SULT2A1 5 0.26 1.9 0.57
24 INT170184 Negative_regulation of Localization of SULT2A1 1 0.25 1.56 0.54
25 INT10604 Gene_expression of SULT1A2 12 0.76 0.72 0.52
26 INT278679 Negative_regulation of Gene_expression of SULT2A1 5 0.25 2.17 0.52
27 INT170186 Negative_regulation of Regulation of SULT2A1 1 0.25 0.84 0.45
28 INT225772 Regulation of Gene_expression of Enpp1 1 0.62 1.6 0.4
29 INT137602 Positive_regulation of SULT1A2 2 0.05 1.1 0.34
30 INT177597 Gene_expression of SULT4A1 6 0.61 0 0.31
31 INT206436 Binding of SULT4A1 1 0.32 0 0.31
32 INT109156 Negative_regulation of ENPP1 2 0.34 1.34 0.29
33 INT88769 Negative_regulation of SULT1A2 1 0.27 0.19 0.29
34 INT206445 Binding of SULT1A1 2 0.30 0.24 0.23
35 INT278655 Negative_regulation of Gene_expression of SULT1E1 1 0.19 0 0.22
36 INT278659 Transcription of SULT2A1 1 0.40 0.25 0.21
37 INT206433 Negative_regulation of SULT1B1 3 0.48 1.25 0.18
38 INT21821 Localization of SULT1A1 1 0.73 0 0.18
39 INT109870 Binding of SULT1A2 2 0.06 1.6 0.17
40 INT100431 Negative_regulation of SULT4A1 2 0.43 0 0.16
41 INT278669 Positive_regulation of SULT2A1 2 0.41 1.95 0.16
42 INT175900 Regulation of ENPP1 1 0.00 1.96 0.16
43 INT252419 Phosphorylation of Enpp1 1 0.08 0.21 0.16
44 INT225771 Negative_regulation of Gene_expression of Enpp1 4 0.43 3.68 0.13
45 INT278665 Positive_regulation of Transcription of SULT2A1 1 0.29 0 0.12
46 INT326802 Protein_catabolism of SULT1A1 1 0.08 0.38 0.11
47 INT206456 Positive_regulation of SULT4A1 1 0.42 0 0.11
48 INT285392 Transcription of SULT1A2 1 0.01 0.06 0.1
49 INT278654 Phosphorylation of SULT2A1 2 0.60 0.29 0.08
50 INT206462 Positive_regulation of SULT1B1 1 0.39 0 0.08
51 INT290612 Positive_regulation of Negative_regulation of SULT2A1 1 0.23 0.51 0.08
52 INT316393 Binding of SULT2A1 1 0.35 0.07 0.07
53 INT278671 Positive_regulation of Gene_expression of SULT1A2 1 0.05 0.57 0.07
54 INT326140 Transcription of SULT1B1 1 0.17 0.87 0.06
55 INT189231 Binding of ENPP1 1 0.07 0.56 0.06
56 INT326141 Localization of SULT1B1 1 0.24 0.63 0.04
57 INT206458 Localization of SULT1C2 1 0.63 0 0.03
58 INT206453 Binding of SULT1B1 1 0.31 0.13 0.03
59 INT319969 Positive_regulation of Negative_regulation of Enpp1 1 0.06 0.77 0.03
60 INT206434 Positive_regulation of Localization of SULT1C2 1 0.42 0 0.03
61 INT206448 Positive_regulation of SULT1C2 1 0.42 0 0
62 INT206439 Phosphorylation of SULT4A1 1 0.73 0 0
63 INT206449 Gene_expression of SULT1C2 1 0.57 0 0
64 INT326807 Positive_regulation of SULT1A1 1 0.06 0.1 0
65 INT320058 Regulation of SULT4A1 1 0.24 0 0
66 INT278663 Positive_regulation of Positive_regulation of SULT1A2 1 0.03 0.19 0
67 INT290613 Positive_regulation of Positive_regulation of SULT2A1 1 0.23 0.74 0
68 INT326801 Regulation of Gene_expression of SULT1A1 1 0.03 0.06 0
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