GO:0050544

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Name arachidonic acid binding
Categary Function
Go Slim No
Go Link GO:0050544
Unique Molecular Interactions 95
Total Molecular Interactions 116
Total Single Events 1455
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for arachidonic acid binding. They are ordered first by their pain relevance and then by number of times they were reported for arachidonic acid binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT275850 Binding of NDUFAB1 and SNCA 1 0.00 3.78 3.16
2 INT203168 PTGER2 Negative_regulation of Gene_expression of ALOX5AP 1 0.03 2.4 1.18
3 INT203162 PTGER2 Regulation of Gene_expression of ALOX5AP 1 0.04 1.47 0.94
4 INT158068 Positive_regulation of Pparg Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.28 0.76
5 INT23681 Negative_regulation of Binding of Stx3 and Chrna7 1 0.00 0 0.75
6 INT23680 Binding of Stx3 and Chrna7 1 0.00 0 0.75
7 INT312101 ELANE Regulation of ALOX5AP 1 0.21 1.11 0.73
8 INT164286 Alox5ap Positive_regulation of Cysltr2 1 0.19 1.11 0.61
9 INT164284 Ltb4r Positive_regulation of Alox5ap 1 0.34 1.1 0.6
10 INT23679 Chrna7 Regulation of Binding of Stx3 1 0.00 0 0.56
11 INT107703 PPARG Regulation of Gene_expression of CPOX 1 0.16 0.15 0.41
12 INT203167 Gene_expression of PTGER2 Positive_regulation of Gene_expression of ALOX5AP 1 0.03 0.67 0.38
13 INT312102 Binding of ALOX5 and ALOX5AP 1 0.10 0.65 0.36
14 INT122169 AKR1C3 Regulation of PPARG 1 0.45 0.26 0.33
15 INT116292 Gm9662 Negative_regulation of Pparg 1 0.00 0 0.33
16 INT116291 Gm9662 Negative_regulation of Positive_regulation of Pparg 1 0.00 0 0.32
17 INT148556 PPARG Regulation of Gene_expression of PPARA 1 0.30 1.2 0.31
18 INT122168 AKR1C1 Regulation of PPARG 1 0.12 0.25 0.31
19 INT328407 Nlrp1a Negative_regulation of Gene_expression of Snca 1 0.07 0.31 0.29
20 INT328410 Nlrp1a Negative_regulation of Snca 1 0.07 0.31 0.29
21 INT110373 CYP4A11 Positive_regulation of PPARG 1 0.00 0.94 0.26
22 INT261375 Binding of Nsdhl and Pparg 1 0.05 1.03 0.25
23 INT130056 PPARG Positive_regulation of CAV1 1 0.02 0.53 0.25
24 INT130060 PPARG Positive_regulation of Positive_regulation of Egr1 1 0.22 0.46 0.24
25 INT115148 PPARG Negative_regulation of Gene_expression of INSIG2 1 0.01 0.34 0.21
26 INT312091 ALOX5AP Regulation of Transcription of ALOX5 1 0.13 0.37 0.18
27 INT81296 Positive_regulation of Pparg Regulation of Gene_expression of Hmox1 1 0.25 0.17 0.17
28 INT317322 Snca Regulation of Positive_regulation of Th 1 0.01 0.23 0.17
29 INT81297 Positive_regulation of Pparg Regulation of Gene_expression of Nos2 1 0.23 0.17 0.17
30 INT312089 LTB4R Positive_regulation of ALOX5AP 1 0.01 0.32 0.16
31 INT312126 ELANE Positive_regulation of ALOX5AP 1 0.20 0.25 0.15
32 INT106506 Binding of Pparg and Ptgds 1 0.42 0.31 0.14
33 INT276228 Nrtim1 Positive_regulation of PPARG 1 0.01 2.18 0.14
34 INT115140 PPARG Positive_regulation of EGR1 1 0.36 0.45 0.13
35 INT109410 RASGRP1 Regulation of Gene_expression of PPARG 1 0.03 0.76 0.13
36 INT115145 PPARG Positive_regulation of TFAM 1 0.04 0.45 0.13
37 INT101173 Pparg Regulation of Positive_regulation of Nfkb1 1 0.03 0.07 0.12
38 INT101174 Pparg Regulation of Gene_expression of IK 1 0.00 0.07 0.12
39 INT158141 Binding of HOXD13 and SNCA 1 0.54 0.41 0.11
40 INT312116 Negative_regulation of PTGER2 Regulation of Gene_expression of ALOX5AP 1 0.04 0.2 0.1
41 INT328413 Binding of Snca and Nlrp1a 1 0.06 0.75 0.1
42 INT157265 PPARG Positive_regulation of PPARA 1 0.22 1.15 0.09
43 INT157276 PPARG Positive_regulation of Adipoq 1 0.29 1.09 0.09
44 INT83270 Snca Regulation of Napepld 1 0.14 0 0.09
45 INT289536 Sirt1 Negative_regulation of Localization of Pparg 1 0.13 0.43 0.08
46 INT313503 Binding of ALOX5AP and CXADRP1 1 0.01 1.51 0.08
47 INT312093 ELANE Regulation of Gene_expression of ALOX5AP 1 0.13 0.15 0.08
48 INT110377 Binding of Ncoa1 and Pparg 1 0.02 0.26 0.08
49 INT289603 Sirt1 Negative_regulation of Localization of PPARG 1 0.02 0.43 0.08
50 INT289533 Sirt1 Negative_regulation of Pparg 1 0.18 0.42 0.07
51 INT289602 Sirt1 Negative_regulation of PPARG 1 0.02 0.37 0.07
52 INT312113 ELANE Positive_regulation of Gene_expression of ALOX5AP 1 0.23 0.14 0.07
53 INT332641 Binding of PPARG and Ins1 1 0.12 1.05 0.05
54 INT313504 Binding of ALOX5AP and SNRNP70 1 0.04 0.5 0.05
55 INT229371 Positive_regulation of Pparg Negative_regulation of Gene_expression of Edn1 1 0.01 0.92 0.04
56 INT120449 Pparg Positive_regulation of Negative_regulation of Il2 1 0.75 0 0.04
57 INT312117 Negative_regulation of ELANE Positive_regulation of ALOX5AP 1 0.17 0.08 0.04
58 INT313551 Binding of ALOX5AP and Cor 1 0.02 1.01 0.03
59 INT348592 Binding of HDAC1 and PPARG 1 0.23 0 0.03
60 INT348583 MECP2 Regulation of PPARG 1 0.46 0.73 0
61 INT348594 MECP2 Regulation of Gene_expression of PPARG 1 0.34 0.43 0
62 INT187621 Gnrh1 Regulation of Gene_expression of Pparg 1 0.00 0.09 0
63 INT290027 Binding of PPARG and NR1H4 1 0.03 0.39 0
64 INT348584 EZH2 Regulation of Gene_expression of PPARG 1 0.30 0.43 0
65 INT317313 Atp13a2 Negative_regulation of Snca 1 0.13 0.59 0
66 INT290031 Binding of INS and PPARG 1 0.11 0.47 0
67 INT290022 Binding of PPARG and DDX12P 1 0.00 1.77 0
68 INT348593 ZACN Regulation of Positive_regulation of PPARG 1 0.14 0.41 0
69 INT313499 Binding of ALOX5AP and CRP 1 0.07 0.45 0
70 INT290030 Binding of PPARD and PPARG 1 0.09 0.38 0
71 INT290024 Binding of PPARG and RXRG 1 0.15 0.39 0
72 INT313502 Binding of ALOX5AP and ADIPOQ 1 0.05 0.44 0
73 INT317315 Gene_expression of Snca Negative_regulation of Psmb10 1 0.00 0.52 0
74 INT317320 Binding of Snca and Atp13a2 1 0.08 0.58 0
75 INT348587 Binding of MECP2 and PPARG 1 0.32 0.25 0
76 INT130602 Pparg Regulation of Pscs 1 0.11 0.29 0
77 INT187623 Lhb Regulation of Gene_expression of Pparg 1 0.02 0.09 0
78 INT348586 RSPH1 Positive_regulation of Gene_expression of PPARG 1 0.02 0.23 0
79 INT290026 Binding of PPARG and CHDH 1 0.10 6.61 0
80 INT298871 ALOX5AP Positive_regulation of RAB7A 1 0.09 0.35 0
81 INT348585 EZH2 Regulation of PPARG 1 0.41 0.73 0
82 INT348595 Binding of PPARG and ZACN 1 0.07 0.38 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for arachidonic acid binding. They are ordered first by their pain relevance and then by number of times they were reported in arachidonic acid binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT67613 Positive_regulation of PPARG 94 0.70 69.15 34.38
2 INT67610 Positive_regulation of Pparg 53 0.70 31.91 25.2
3 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42
4 INT67608 Gene_expression of Pparg 41 0.78 25.09 19.53
5 INT195414 Gene_expression of ALOX5AP 65 0.72 31.22 15.25
6 INT67611 Positive_regulation of Pparg 39 0.69 18.33 13.23
7 INT123593 Gene_expression of Snca 58 0.78 35.76 12.87
8 INT79685 Positive_regulation of Gene_expression of Pparg 17 0.70 14.63 11.03
9 INT127123 Positive_regulation of Snca 35 0.70 14.76 10.1
10 INT67612 Binding of PPARG 38 0.48 22.67 8.94
11 INT103399 Positive_regulation of Positive_regulation of Pparg 11 0.66 7 7.36
12 INT67609 Binding of Pparg 17 0.46 9.53 6.06
13 INT100078 Positive_regulation of Positive_regulation of PPARG 11 0.70 3.6 5.86
14 INT123594 Negative_regulation of Snca 19 0.59 4.43 4.59
15 INT127122 Positive_regulation of Gene_expression of Snca 11 0.69 15.36 4.56
16 INT73626 Positive_regulation of Gene_expression of PPARG 22 0.70 18.82 4.4
17 INT79692 Negative_regulation of PPARG 24 0.59 16 4.31
18 INT72936 Gene_expression of Pparg 39 0.77 19.01 4.02
19 INT112070 Negative_regulation of Gene_expression of Pparg 6 0.59 3.72 3.96
20 INT78845 Binding of Pparg 16 0.44 11.67 3.53
21 INT119412 Gene_expression of Snca 15 0.66 11.27 3.39
22 INT110245 Gene_expression of SNCA 11 0.77 8.29 3.36
23 INT195415 Regulation of Gene_expression of ALOX5AP 10 0.45 6.43 3.13
24 INT110956 Negative_regulation of Positive_regulation of Pparg 5 0.41 3.68 3.11
25 INT112071 Regulation of Gene_expression of Pparg 4 0.62 4.62 3.09
26 INT123595 Regulation of Snca 7 0.62 4.3 3.06
27 INT99187 Negative_regulation of Positive_regulation of PPARG 5 0.42 5.07 2.99
28 INT195421 Positive_regulation of Gene_expression of ALOX5AP 12 0.49 5.17 2.82
29 INT81294 Negative_regulation of Positive_regulation of Pparg 7 0.58 4.39 2.2
30 INT78844 Regulation of Pparg 6 0.41 4 2.19
31 INT127124 Regulation of Gene_expression of Snca 2 0.62 0.17 2.03
32 INT127125 Localization of Snca 6 0.81 8.24 1.88
33 INT200779 Negative_regulation of Gene_expression of ALOX5AP 7 0.41 3.75 1.79
34 INT148266 Positive_regulation of SNCA 5 0.67 3.17 1.74
35 INT164275 Gene_expression of Alox5ap 3 0.55 3.79 1.72
36 INT200778 Positive_regulation of ALOX5AP 3 0.49 2.54 1.7
37 INT117438 Positive_regulation of Gene_expression of Pparg 11 0.69 8 1.63
38 INT79691 Regulation of Gene_expression of PPARG 10 0.50 10.44 1.62
39 INT79690 Negative_regulation of Gene_expression of PPARG 10 0.59 10.48 1.55
40 INT122204 Positive_regulation of Alox5ap 1 0.26 0.23 1.53
41 INT201271 Phosphorylation of Snca 3 0.82 4.22 1.45
42 INT124247 Negative_regulation of Gene_expression of Snca 12 0.59 3.87 1.39
43 INT23668 Binding of Stx3 1 0.01 0 1.31
44 INT110244 Positive_regulation of Gene_expression of SNCA 5 0.69 4.66 1.19
45 INT151753 Transcription of Snca 6 0.69 1.99 1.11
46 INT79689 Regulation of PPARG 10 0.62 8.04 1.07
47 INT292945 Positive_regulation of Positive_regulation of Snca 4 0.69 2.42 1.05
48 INT98817 Regulation of Pparg 3 0.26 1.62 1.03
49 INT286344 Positive_regulation of Gene_expression of Snca 1 0.41 2.84 1.03
50 INT151752 Positive_regulation of Transcription of Snca 2 0.50 0.99 0.92
51 INT107714 Localization of PPARG 4 0.73 0.88 0.91
52 INT124246 Binding of Snca 10 0.37 6.53 0.9
53 INT103400 Transcription of Pparg 2 0.67 3.15 0.85
54 INT68926 Binding of ALOX5AP 8 0.36 4.02 0.84
55 INT23671 Negative_regulation of Stx3 1 0.01 0 0.75
56 INT110089 Positive_regulation of Binding of PPARG 1 0.70 1.04 0.7
57 INT94148 Positive_regulation of Binding of Pparg 2 0.43 1.16 0.66
58 INT116288 Negative_regulation of Pparg 4 0.42 1.69 0.62
59 INT164276 Localization of Alox5ap 1 0.61 1.1 0.6
60 INT165706 Negative_regulation of Negative_regulation of PPARG 3 0.23 1.05 0.58
61 INT115156 Regulation of Positive_regulation of PPARG 2 0.25 0.86 0.54
62 INT130600 Negative_regulation of Binding of Pparg 1 0.42 1.96 0.54
63 INT144098 Localization of Pparg 2 0.59 0.73 0.52
64 INT158946 Negative_regulation of Pparg 3 0.43 1.53 0.51
65 INT73624 Transcription of PPARG 7 0.72 3.25 0.49
66 INT122205 Negative_regulation of Alox5ap 1 0.24 0 0.45
67 INT148264 Transcription of SNCA 1 0.40 0.25 0.42
68 INT98818 Regulation of Positive_regulation of Pparg 1 0.03 0.14 0.41
69 INT343972 Negative_regulation of Binding of SNCA 1 0.36 0.2 0.39
70 INT78849 Transcription of Pparg 3 0.53 2.31 0.38
71 INT195416 Regulation of ALOX5AP 2 0.53 0.8 0.38
72 INT195413 Negative_regulation of ALOX5AP 5 0.37 1.39 0.37
73 INT169628 Binding of SNCA 4 0.47 3.53 0.36
74 INT81290 Positive_regulation of Positive_regulation of Pparg 1 0.45 0.37 0.36
75 INT107713 Positive_regulation of Localization of PPARG 1 0.59 0.07 0.36
76 INT78847 Positive_regulation of Transcription of Pparg 2 0.44 0.47 0.35
77 INT343973 Localization of SNCA 1 0.63 0.07 0.3
78 INT166885 Negative_regulation of Gene_expression of Pparg 5 0.41 2.6 0.26
79 INT158945 Negative_regulation of Negative_regulation of Pparg 1 0.43 0.73 0.26
80 INT78848 Regulation of Binding of Pparg 1 0.45 0.5 0.25
81 INT142052 Binding of Snca 4 0.47 1.02 0.22
82 INT203173 Localization of ALOX5AP 3 0.48 0.78 0.21
83 INT259884 Negative_regulation of Binding of ALOX5AP 1 0.10 0.46 0.21
84 INT178257 Positive_regulation of Transcription of Pparg 1 0.49 2.25 0.21
85 INT292944 Regulation of Positive_regulation of Snca 1 0.45 0.36 0.21
86 INT161753 Regulation of Gene_expression of Pparg 2 0.35 1.28 0.19
87 INT312127 Positive_regulation of Positive_regulation of ALOX5AP 1 0.35 0.37 0.19
88 INT257418 Negative_regulation of Transcription of Snca 1 0.43 0.93 0.19
89 INT312137 Transcription of ALOX5AP 1 0.50 0.37 0.18
90 INT81292 Regulation of Positive_regulation of Pparg 1 0.41 0.17 0.17
91 INT166361 Phosphorylation of SNCA 1 0.70 0.72 0.17
92 INT157084 Localization of Snca 1 0.51 0.17 0.16
93 INT343974 Negative_regulation of Gene_expression of SNCA 1 0.31 0.09 0.16
94 INT319289 Protein_catabolism of Snca 1 0.35 0.93 0.15
95 INT286343 Negative_regulation of Gene_expression of Snca 1 0.26 0.65 0.15
96 INT115155 Phosphorylation of PPARG 1 0.58 0.44 0.13
97 INT312135 Negative_regulation of Regulation of ALOX5AP 1 0.30 0.19 0.13
98 INT101172 Localization of Pparg 6 0.58 3.62 0.12
99 INT78846 Negative_regulation of Regulation of Pparg 1 0.32 0.23 0.12
100 INT229009 Positive_regulation of Localization of Pparg 1 0.39 1.86 0.1
101 INT166890 Regulation of Binding of ALOX5AP 1 0.44 0.1 0.1
102 INT288642 Negative_regulation of Positive_regulation of Snca 1 0.07 0.93 0.09
103 INT292946 Positive_regulation of Localization of Snca 1 0.50 0.52 0.06
104 INT312129 Positive_regulation of Transcription of ALOX5AP 1 0.35 0.1 0.05
105 INT312132 Regulation of Regulation of ALOX5AP 1 0.28 0.06 0.03
106 INT317275 Positive_regulation of Binding of Snca 1 0.37 0.53 0
107 INT229010 Phosphorylation of Pparg 1 0.63 2.95 0
108 INT290036 Regulation of Binding of PPARG 1 0.45 0.66 0
109 INT348617 Regulation of Negative_regulation of PPARG 1 0.24 0.42 0
110 INT332933 Regulation of Transcription of PPARG 1 0.43 1.71 0
111 INT332925 Protein_catabolism of PPARG 1 0.63 1.04 0
112 INT343971 Positive_regulation of Positive_regulation of SNCA 1 0.42 0.35 0
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