GO:0050661

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Name NADP binding
Categary Function
Go Slim No
Go Link GO:0050661
Unique Molecular Interactions 706
Total Molecular Interactions 889
Total Single Events 14536
Pain Genes Associated 45

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for NADP binding. They are ordered first by their pain relevance and then by number of times they were reported for NADP binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT317517 Binding of Nos1 and Oprm1 1 0.17 0.22 3.85
2 INT108472 Binding of NOS1 and PNOC 1 0.32 0.64 3.27
3 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
4 INT251150 Binding of Nos1 and Dlg2 1 0.30 1.98 2.62
5 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
6 INT349658 Nos2 Regulation of Gene_expression of Nos1 1 0.63 2.86 1.84
7 INT142899 Chn1 Negative_regulation of Positive_regulation of NOS1 1 0.01 1.07 1.75
8 INT278223 Binding of NOS3 and ACSM3 1 0.41 6.32 1.65
9 INT168612 Negative_regulation of Nos1 Negative_regulation of Positive_regulation of Mmp9 1 0.23 0.45 1.62
10 INT168607 Negative_regulation of Nos1 Negative_regulation of Mmp9 1 0.23 0.45 1.61
11 INT168611 Binding of Mmp9 and Ndor1 1 0.29 0.41 1.57
12 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56
13 INT351246 Binding of OPN1LW and NNT 1 0.03 0.53 1.45
14 INT134764 Ghrl Regulation of Gene_expression of NOS3 1 0.02 2.66 1.4
15 INT158762 Binding of Vwf and Mthfr 1 0.05 1.85 1.37
16 INT135830 Gch1 Regulation of Nos2 1 0.65 0 1.29
17 INT42580 CAT Negative_regulation of POMC 1 0.20 0.42 1.26
18 INT132465 Ltf Positive_regulation of Nos1 1 0.35 0.05 1.24
19 INT69504 Binding of Nos1 and Gatm 1 0.05 0 1.13
20 INT142572 D5Pas1 Negative_regulation of Nos1 2 0.02 0.14 1.11
21 INT317527 Binding of Hint1 and Nos1 1 0.27 0.1 1.11
22 INT56990 Cat Regulation of Efs 1 0.26 0 1.05
23 INT88875 Ifng Positive_regulation of Transcription of Nos2 1 0.02 0.27 1.03
24 INT132464 Ltf Negative_regulation of Positive_regulation of Nos1 1 0.33 0 1.03
25 INT323278 Dhfr Negative_regulation of Negative_regulation of Igkv1-131 1 0.02 0.93 1.02
26 INT88887 IRF6 Positive_regulation of Transcription of Nos2 1 0.21 0.27 1.02
27 INT88874 Ifng Regulation of Nos2 1 0.01 0.26 1.01
28 INT119914 Olr1714 Negative_regulation of Nos1 1 0.02 0.47 1.01
29 INT88884 IRF6 Regulation of Nos2 1 0.12 0.26 1
30 INT317555 Nos1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
31 INT88886 IRF6 Positive_regulation of Nos2 1 0.22 0.26 1
32 INT88888 Regulation of IRF6 Positive_regulation of Nos2 1 0.20 0.26 1
33 INT130232 Binding of Cat and Sod1 1 0.35 0.3 0.98
34 INT130231 Positive_regulation of Binding of Cat and Sod1 1 0.46 0.3 0.98
35 INT317567 Binding of Akt1 and Nos1 1 0.22 0 0.96
36 INT146579 Hba Negative_regulation of Gene_expression of Nos2 1 0.44 1.01 0.95
37 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
38 INT165280 Tnf Positive_regulation of Gene_expression of Nos2 1 0.24 1.02 0.91
39 INT161655 Gsr Regulation of Gene_expression of Il1b 1 0.20 1.84 0.9
40 INT317530 Negative_regulation of Binding of Nos1 and Oprm1 1 0.21 0.06 0.9
41 INT108687 Nfkb1 Regulation of Positive_regulation of Nos2 1 0.50 1.28 0.88
42 INT108686 Nfkb1 Regulation of Nos2 1 0.69 1.27 0.88
43 INT160412 Tat Positive_regulation of Transcription of Nos2 1 0.37 0.98 0.86
44 INT120825 Adcyap1 Positive_regulation of Localization of Nos1 1 0.26 0.62 0.85
45 INT243678 Binding of GSR and Ugcg 2 0.03 2.84 0.83
46 INT102931 Nos3 Positive_regulation of Nos2 1 0.43 1.63 0.83
47 INT152236 Tlr4 Regulation of Gene_expression of Nos2 3 0.19 0.64 0.82
48 INT155761 Binding of Nos1 and Tjp1 1 0.13 1.01 0.82
49 INT185937 NOS2 Regulation of Prkaca 1 0.03 1.08 0.82
50 INT322266 Binding of LIG4 and NOS3 1 0.02 2.35 0.82
51 INT102932 Nos3 Positive_regulation of NOS1 1 0.03 1.63 0.82
52 INT155760 Binding of Nos1 and Dlg4 1 0.13 1.01 0.82
53 INT235087 NOS1 Positive_regulation of Localization of ABAT 1 0.02 0.61 0.81
54 INT88885 IRF6 Positive_regulation of Gene_expression of Nos2 1 0.21 0.1 0.81
55 INT88878 Negative_regulation of Nfkb1 Positive_regulation of Gene_expression of Nos2 1 0.06 0.1 0.81
56 INT164607 Positive_regulation of GSR Positive_regulation of Gpx1 1 0.01 0.33 0.81
57 INT164606 GSR Positive_regulation of Gpx1 1 0.01 0.32 0.8
58 INT349657 Nos2 Regulation of Regulation of Nos1 1 0.24 0.9 0.8
59 INT96501 Il11 Regulation of Gene_expression of NOS2 1 0.00 1.04 0.8
60 INT168455 Sult1a1 Negative_regulation of Nos2 1 0.08 1.99 0.79
61 INT168456 Arr3 Positive_regulation of Nos2 1 0.21 1.98 0.79
62 INT132889 Nfkb1 Regulation of Gene_expression of Nos2 1 0.16 0.21 0.79
63 INT132894 CHUK Regulation of Gene_expression of Nos2 1 0.00 0.21 0.79
64 INT168457 Sult1a1 Positive_regulation of Cat 1 0.15 1.56 0.78
65 INT97863 Binding of NOS1 and GRHPR 1 0.05 0.23 0.77
66 INT90120 Jun Positive_regulation of Gene_expression of Nos1 1 0.38 0.39 0.76
67 INT90117 Jun Regulation of Gene_expression of Nos1 1 0.21 0.39 0.76
68 INT90125 Nfkb1 Regulation of Gene_expression of Nos1 1 0.17 0.39 0.76
69 INT178576 CNTN2 Positive_regulation of DPYD 1 0.05 2.18 0.76
70 INT90116 Nfkb1 Positive_regulation of Gene_expression of Nos1 1 0.32 0.39 0.76
71 INT34825 Aap Negative_regulation of Gsr 1 0.01 0.3 0.75
72 INT31776 Positive_regulation of Gclc Positive_regulation of G6pd 1 0.29 0.19 0.75
73 INT108611 Adra2a Regulation of Gene_expression of Nos1 1 0.10 0 0.75
74 INT128815 Mapk14 Regulation of Gene_expression of Nos2 1 0.21 0.46 0.74
75 INT159593 Regulation of Nfkb1 Positive_regulation of Gene_expression of Nos2 1 0.38 0.46 0.74
76 INT128813 Mapk8 Regulation of Gene_expression of Nos2 1 0.23 0.46 0.74
77 INT213026 Hdl1 Positive_regulation of Nos3 5 0.16 7.92 0.73
78 INT314203 Nos2 Positive_regulation of Gli3 1 0.19 1.27 0.73
79 INT220033 Casp3 Positive_regulation of Gene_expression of Nos1 1 0.05 0.52 0.72
80 INT187522 ATIC Negative_regulation of Gene_expression of Nos2 1 0.02 1.46 0.7
81 INT149983 Binding of Cpox and Nos2 1 0.30 0.54 0.69
82 INT26230 Binding of GSR and HTR1D 1 0.12 0.15 0.69
83 INT106154 Calca Positive_regulation of Nos1 1 0.29 0.2 0.68
84 INT347962 Cpox Negative_regulation of Positive_regulation of Nos1 1 0.02 0.59 0.67
85 INT278965 LEP Positive_regulation of Gene_expression of NOS2 2 0.29 2.12 0.66
86 INT26231 Binding of GSR and HTR1B 1 0.12 0.15 0.66
87 INT220032 Nos1 Positive_regulation of Nos3 1 0.32 0.45 0.66
88 INT220035 Nos1 Positive_regulation of Nos2 1 0.29 0.45 0.66
89 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65
90 INT118824 OPA1 Positive_regulation of Gene_expression of Nos1 2 0.03 0.24 0.65
91 INT78663 Dlst Regulation of Nos1 1 0.19 0.91 0.65
92 INT135829 Cat2 Regulation of Nos2 1 0.47 0 0.65
93 INT235082 CA2 Positive_regulation of NOS1 2 0.11 0.62 0.63
94 INT266489 Dcps Positive_regulation of Gene_expression of Nos2 1 0.06 3.43 0.63
95 INT127778 Mthfd1 Regulation of Positive_regulation of Mthfr 1 0.01 0.71 0.62
96 INT128812 Mapk8 Negative_regulation of Gene_expression of Nos2 1 0.19 0.37 0.61
97 INT128817 Ephb1 Negative_regulation of Gene_expression of Nos2 1 0.16 0.37 0.61
98 INT124831 Fbp1 Positive_regulation of Nos2 1 0.36 0.64 0.61
99 INT802 Aap Regulation of Grhpr 1 0.01 0 0.6
100 INT339072 Eae1 Positive_regulation of Gene_expression of Nos2 1 0.02 3.76 0.59
101 INT175700 Nos3 Negative_regulation of smc 1 0.01 1.05 0.59
102 INT128810 Il1b Positive_regulation of Gene_expression of Nos2 1 0.04 0.31 0.59
103 INT38131 Pag1 Negative_regulation of Gsr 1 0.01 0.72 0.58
104 INT143426 Positive_regulation of B4GALNT1 Negative_regulation of Gene_expression of Nos2 1 0.00 0.83 0.58
105 INT212813 Tlr4 Positive_regulation of Nos2 3 0.34 0.89 0.57
106 INT347362 RYBP Regulation of Gene_expression of GSR 1 0.01 0 0.57
107 INT151459 Olr1745 Negative_regulation of Gene_expression of Nos2 1 0.04 0.82 0.57
108 INT142571 Pnoc Positive_regulation of Nos1 1 0.52 0.06 0.57
109 INT78588 Positive_regulation of Binding of Nfkb1 and Nos2 1 0.01 0.33 0.56
110 INT81546 TNF Positive_regulation of Gene_expression of Nos2 1 0.04 0.54 0.56
111 INT78587 Binding of Nfkb1 and Nos2 1 0.01 0.33 0.55
112 INT278228 Binding of MBNL1 and NOS3 1 0.05 2.06 0.54
113 INT97425 Prkcg Regulation of Regulation of Nos1 1 0.06 0 0.53
114 INT121081 Negative_regulation of NOS1 Negative_regulation of Slep1 1 0.00 0 0.52
115 INT191947 NFKB2 Positive_regulation of Gene_expression of NOS2 1 0.08 1.51 0.52
116 INT347369 RYBP Positive_regulation of GSR 1 0.01 0.43 0.51
117 INT323280 Dhfr Negative_regulation of Igkv1-131 1 0.02 0.47 0.51
118 INT78590 Nos2 Positive_regulation of PTGS1 2 0.00 0.85 0.5
119 INT308656 Pik3r1 Positive_regulation of Nos3 1 0.02 1.8 0.5
120 INT317537 Oprm1 Positive_regulation of Phosphorylation of Nos1 1 0.16 0 0.5
121 INT347395 RYBP Positive_regulation of Gsr 1 0.01 0.43 0.5
122 INT90131 NOS1 Regulation of Fos 1 0.00 0.25 0.49
123 INT235090 Positive_regulation of GRIN1 Positive_regulation of NOS1 1 0.42 0.81 0.49
124 INT132060 NBN Positive_regulation of Nos2 1 0.01 0.21 0.49
125 INT212806 Rngtt Negative_regulation of Gene_expression of Nos2 1 0.03 0.9 0.49
126 INT186713 IK Positive_regulation of Gene_expression of NOS1 1 0.00 0.55 0.49
127 INT90121 Nos1 Regulation of Fos 1 0.27 0.25 0.49
128 INT347367 RYBP Negative_regulation of GSR 1 0.01 0.09 0.48
129 INT347364 RYBP Regulation of GSR 1 0.01 0.06 0.48
130 INT116337 Binding of GRIN1 and NDOR1 1 0.03 0 0.48
131 INT191948 NFKB1 Regulation of Gene_expression of NOS2 1 0.38 1 0.47
132 INT136141 Hsd11b1 Positive_regulation of Gene_expression of Agrp 1 0.64 0.2 0.47
133 INT191950 NFKB2 Regulation of Gene_expression of NOS2 1 0.08 1 0.47
134 INT72928 Magel2 Negative_regulation of Positive_regulation of NOS1 1 0.01 0 0.47
135 INT257220 Binding of Nos1 and Flvcr2 1 0.00 0.17 0.47
136 INT162932 TXNRD1 Negative_regulation of Phosphorylation of AKT1 1 0.14 1.01 0.47
137 INT149652 Zfp36 Regulation of Nos2 1 0.09 0.42 0.47
138 INT161662 Gsr Regulation of Gene_expression of TNF 1 0.01 0.93 0.46
139 INT314200 Positive_regulation of Binding of Nos2 and Tnf 1 0.42 0.34 0.46
140 INT103025 Calca Positive_regulation of Nos3 1 0.25 0.41 0.46
141 INT161653 Gsr Regulation of Gene_expression of Ifih1 1 0.04 1.05 0.46
142 INT314201 Binding of Nos2 and Tnf 1 0.31 0.33 0.46
143 INT103027 Ptgis Positive_regulation of Nos3 1 0.06 0.42 0.46
144 INT95276 Obfc2a Negative_regulation of Nos3 1 0.02 1.02 0.46
145 INT161652 Gsr Regulation of Gene_expression of Tnf 1 0.17 0.98 0.46
146 INT103030 Calca Positive_regulation of Positive_regulation of Nos3 1 0.26 0.41 0.46
147 INT28863 Mtr Negative_regulation of Dhfr 1 0.04 0.87 0.45
148 INT354981 Cacna1a Negative_regulation of Gene_expression of Nos2 1 0.01 0.99 0.45
149 INT241912 Cat Positive_regulation of Ros1 1 0.03 0.76 0.44
150 INT28864 Mtx1 Negative_regulation of Dhfr 1 0.19 0.87 0.44
151 INT116610 Positive_regulation of Lnpep Regulation of Nos2 1 0.16 0.62 0.44
152 INT116608 Lnpep Regulation of Nos2 1 0.14 0.62 0.44
153 INT27997 Oprd1 Positive_regulation of Localization of Me1 1 0.03 0 0.44
154 INT148634 Abat Negative_regulation of Transcription of Nos2 1 0.19 0.52 0.44
155 INT212809 Il6 Positive_regulation of Gene_expression of Nos2 1 0.08 0.75 0.43
156 INT342998 DUOX1 Positive_regulation of ROS1 1 0.23 0.25 0.43
157 INT212810 Tlr4 Positive_regulation of Gene_expression of Nos2 1 0.03 0.74 0.43
158 INT159349 Zfp956 Negative_regulation of Nos1 1 0.03 0.61 0.43
159 INT161654 Gsr Regulation of Gpx1 1 0.14 0.85 0.42
160 INT116611 Lnpep Positive_regulation of Binding of Nos2 1 0.16 0.62 0.42
161 INT111410 Nos1 Regulation of Vip 1 0.00 0 0.41
162 INT135972 Nfkb1 Positive_regulation of Gene_expression of Nos2 1 0.04 0.54 0.41
163 INT146273 Binding of Nos1 and Rasd1 1 0.34 0.18 0.41
164 INT161074 Ccbl1 Negative_regulation of Gsr 1 0.00 0 0.41
165 INT111409 Nos1 Regulation of Gene_expression of Vip 1 0.01 0 0.41
166 INT156438 Cpox Positive_regulation of Nos2 3 0.14 1.24 0.4
167 INT97789 Positive_regulation of Cnr1 Negative_regulation of Gene_expression of Nos2 1 0.12 0.23 0.4
168 INT187487 Cebpg Positive_regulation of Gene_expression of Nos2 1 0.03 0.38 0.4
169 INT81300 Tlr4 Positive_regulation of Gene_expression of Nos2 1 0.02 0.38 0.39
170 INT146272 Binding of Nos1 and Nos1ap 1 0.28 0.2 0.39
171 INT201274 Car2 Regulation of Gene_expression of Nos1 1 0.05 1.15 0.38
172 INT61954 IFNA1 Positive_regulation of Nos2 1 0.05 0.46 0.38
173 INT109683 NOS1 Positive_regulation of Positive_regulation of ISYNA1 1 0.01 0.11 0.38
174 INT235091 CALM1 Positive_regulation of NOS1 1 0.02 0.63 0.37
175 INT320591 Ca2 Positive_regulation of Nos1 1 0.07 0.09 0.37
176 INT168426 RYBP Regulation of Nos2 1 0.01 0.4 0.36
177 INT80444 Binding of EDNRA and SPR 1 0.05 0.1 0.36
178 INT168424 Ptger2 Regulation of Binding of Nos2 1 0.22 0.52 0.36
179 INT97790 Foxm1 Negative_regulation of Gene_expression of Nos2 1 0.03 0.16 0.36
180 INT152240 Nfasc Regulation of Gene_expression of Nos2 1 0.06 0.19 0.36
181 INT308889 Binding of Idh1 and Adp 1 0.02 0 0.36
182 INT168423 Ptger2 Regulation of Nos2 1 0.13 0.52 0.36
183 INT278226 Binding of FOSB and NOS3 1 0.03 1.22 0.36
184 INT308890 Binding of Idh1 and P2ry13 1 0.06 0 0.35
185 INT89500 Nos2 Positive_regulation of Il6 1 0.04 1.07 0.35
186 INT255803 Cat Negative_regulation of Gene_expression of Il6 1 0.05 0.35 0.35
187 INT198970 GAPDH Negative_regulation of ADAMTS3 1 0.47 0 0.35
188 INT323885 LEP Regulation of Gene_expression of NOS2 1 0.26 1.07 0.35
189 INT198971 GAPDH Negative_regulation of ADAMTS5 1 0.47 0 0.35
190 INT198969 GAPDH Negative_regulation of TIMP1 1 0.47 0 0.35
191 INT187488 Positive_regulation of Ros1 Positive_regulation of Gene_expression of Nos2 1 0.01 0.88 0.35
192 INT175319 Negative_regulation of Nos2 Negative_regulation of Positive_regulation of Pnlip 1 0.01 0.83 0.34
193 INT276214 Binding of Nos2 and Nfkb1 1 0.12 0.31 0.34
194 INT89505 Nos2 Positive_regulation of Ptgs2 1 0.05 1.07 0.34
195 INT105768 Binding of Nos1 and Nqo1 1 0.00 0.26 0.34
196 INT354985 Cacna1a Regulation of Nos2 1 0.01 0.73 0.34
197 INT110758 Tnfaip8 Positive_regulation of Positive_regulation of Nos2 1 0.14 0.88 0.34
198 INT276209 Negative_regulation of Binding of Nos2 and Nfkb1 1 0.14 0.31 0.34
199 INT144448 Nqo1 Regulation of Nos1 1 0.11 0.09 0.34
200 INT303126 Nos2 Positive_regulation of Gene_expression of Il6 1 0.13 4.38 0.34

Single Events

The table below shows the top 100 pain related interactions that have been reported for NADP binding. They are ordered first by their pain relevance and then by number of times they were reported in NADP binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08
2 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07
3 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87
4 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85
5 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71
6 INT49171 Gene_expression of Nos1 241 0.78 140.7 104.76
7 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71
8 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43
9 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32
10 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53
11 INT79093 Positive_regulation of Nos1 101 0.70 46.89 59.61
12 INT49170 Negative_regulation of Nos1 116 0.59 60.66 58.87
13 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15
14 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67
15 INT64110 Positive_regulation of Gene_expression of Nos1 68 0.70 58.11 51.64
16 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57
17 INT49028 Positive_regulation of Nos1 102 0.70 34.73 51.05
18 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65
19 INT65245 Gene_expression of Nos3 121 0.78 98.14 41.56
20 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94
21 INT64558 Negative_regulation of Nos1 88 0.58 26.76 36.78
22 INT79060 Gene_expression of NOS2 116 0.78 69.25 34.84
23 INT92837 Negative_regulation of Gene_expression of Nos2 116 0.59 59.67 31.82
24 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72
25 INT61953 Transcription of Nos2 101 0.72 46.64 25.49
26 INT74688 Regulation of Nos1 55 0.62 22.16 25.3
27 INT48766 Regulation of NOS1 73 0.61 37.01 24.59
28 INT89854 Regulation of Nos2 49 0.61 42.58 24.1
29 INT70503 Regulation of Gene_expression of Nos2 71 0.62 44 24.01
30 INT79061 Positive_regulation of NOS2 92 0.65 58.89 23.96
31 INT49172 Regulation of Nos1 43 0.52 27.53 23.66
32 INT16721 Negative_regulation of Cat 56 0.59 44.44 22.84
33 INT70504 Regulation of Gene_expression of NOS1 30 0.51 21.72 21.72
34 INT74059 Positive_regulation of Gene_expression of Nos1 55 0.70 11.5 21.39
35 INT12951 Negative_regulation of Cat 126 0.57 64.39 20.61
36 INT66281 Transcription of Nos2 81 0.71 39.49 20.37
37 INT9246 Positive_regulation of Cat 113 0.70 52.73 18.04
38 INT83198 Positive_regulation of Nos3 78 0.64 35.69 17.71
39 INT61949 Regulation of Nos2 74 0.58 34.08 16.7
40 INT77433 Regulation of Gene_expression of Nos2 49 0.62 35.07 16.33
41 INT12950 Gene_expression of Cat 85 0.75 35.94 15.76
42 INT114025 Transcription of Nos1 20 0.70 16.48 15.63
43 INT74098 Negative_regulation of Gene_expression of Nos1 36 0.59 16.25 14.82
44 INT64112 Regulation of Gene_expression of Nos1 22 0.62 21.45 14.76
45 INT39507 Positive_regulation of TXNRD1 37 0.68 12.47 14.25
46 INT83200 Positive_regulation of Gene_expression of Nos3 48 0.70 24.75 12.99
47 INT121242 Positive_regulation of Gene_expression of Nos3 37 0.69 31.96 12.71
48 INT83201 Gene_expression of NOS3 93 0.78 47.16 12.48
49 INT90909 Negative_regulation of Gene_expression of NOS1 44 0.55 23.83 12.47
50 INT16870 Negative_regulation of Gsr 27 0.59 10.28 11.81
51 INT73431 Positive_regulation of Nos3 82 0.65 53.22 11.61
52 INT97381 Negative_regulation of Positive_regulation of Nos2 34 0.59 16.66 11.6
53 INT95369 Positive_regulation of Gene_expression of NOS2 36 0.55 25.09 11.37
54 INT80251 Binding of Nos1 21 0.30 8.24 11.31
55 INT3845 Gene_expression of GSR 79 0.76 44.69 11.19
56 INT48956 Negative_regulation of Positive_regulation of Nos2 34 0.46 13.15 11.15
57 INT95341 Gene_expression of NDOR1 17 0.75 4.27 10.98
58 INT48912 Localization of NOS1 52 0.77 24.14 10.92
59 INT22132 Positive_regulation of CAT 41 0.67 18.64 10.67
60 INT90114 Regulation of Gene_expression of Nos1 18 0.62 6.38 10.52
61 INT86361 Positive_regulation of Positive_regulation of NOS1 39 0.53 18.93 10.42
62 INT110017 Phosphorylation of Nos1 12 0.60 1.64 10.3
63 INT79720 Positive_regulation of Cat 57 0.70 31.81 10.11
64 INT120509 Gene_expression of Cat 65 0.77 50.9 9.75
65 INT95271 Negative_regulation of Nos3 46 0.53 24.1 9.71
66 INT70850 Positive_regulation of Transcription of Nos2 30 0.70 18.95 9.68
67 INT3846 Positive_regulation of GSR 60 0.50 35.16 9.37
68 INT52924 Negative_regulation of GSR 49 0.58 28.08 9.28
69 INT3703 Negative_regulation of Grhpr 38 0.50 11.43 9.2
70 INT36449 Negative_regulation of G6PD 74 0.59 54.15 8.85
71 INT48908 Transcription of NOS1 27 0.55 13.46 8.39
72 INT84672 Negative_regulation of Positive_regulation of Nos1 12 0.48 3.76 8.27
73 INT116605 Binding of Nos2 28 0.37 16.88 8.18
74 INT72337 Positive_regulation of Positive_regulation of Nos2 37 0.65 17.02 8.11
75 INT114023 Positive_regulation of Transcription of Nos1 7 0.60 5.35 8.06
76 INT71381 Localization of Nos1 33 0.79 11.46 8.05
77 INT76091 Positive_regulation of NOS3 48 0.61 18.4 7.92
78 INT172789 Regulation of Gene_expression of Nos3 15 0.53 16.23 7.86
79 INT112191 Positive_regulation of Transcription of Nos2 22 0.66 12.4 7.74
80 INT85751 Positive_regulation of Positive_regulation of Nos2 40 0.60 23.53 7.72
81 INT5409 Negative_regulation of G6pd 33 0.57 29.21 7.64
82 INT65246 Negative_regulation of Nos3 36 0.50 25.65 7.62
83 INT4228 Gene_expression of CAT 50 0.75 20.62 7.18
84 INT800 Negative_regulation of Grhpr 21 0.42 10.3 7.17
85 INT92741 Positive_regulation of Positive_regulation of Nos1 8 0.47 1.44 6.58
86 INT89131 Negative_regulation of NOS2 20 0.58 9.68 6.56
87 INT83712 Transcription of Nos3 19 0.69 13.09 6.31
88 INT69499 Binding of Nos1 15 0.36 2.56 6.23
89 INT93658 Transcription of Nos1 16 0.72 6.85 6.16
90 INT3645 Positive_regulation of Grhpr 17 0.42 3.64 6.06
91 INT64111 Negative_regulation of Gene_expression of Nos1 22 0.57 8.96 6.02
92 INT48911 Binding of NOS1 24 0.40 11.21 5.89
93 INT257199 Positive_regulation of Phosphorylation of Nos1 2 0.45 0.68 5.78
94 INT94428 Negative_regulation of Gene_expression of NOS2 20 0.47 11.61 5.62
95 INT84673 Localization of Nos1 19 0.80 5.01 5.62
96 INT35536 Negative_regulation of CAT 26 0.57 14.39 5.38
97 INT38366 Regulation of Cat 45 0.62 23.45 5.34
98 INT120511 Positive_regulation of Gene_expression of Cat 26 0.69 19.82 5.2
99 INT86717 Negative_regulation of Positive_regulation of NOS1 18 0.30 8.88 5.2
100 INT5411 Positive_regulation of G6pd 20 0.70 4.74 5.11
101 INT112190 Regulation of Negative_regulation of Nos2 8 0.62 5.83 5.09
102 INT73608 Localization of Nos2 21 0.75 9.58 5.05
103 INT91475 Binding of NDOR1 3 0.27 0.61 4.97
104 INT89132 Regulation of NOS2 9 0.61 7.34 4.95
105 INT61950 Regulation of Positive_regulation of Nos2 17 0.43 9.01 4.87
106 INT100772 Negative_regulation of TXNRD1 10 0.41 3.47 4.74
107 INT121954 Binding of Mthfr 17 0.44 13.47 4.66
108 INT35765 Gene_expression of TXNRD1 47 0.56 9.16 4.43
109 INT76581 Regulation of Negative_regulation of NOS1 14 0.45 7.49 4.4
110 INT94427 Positive_regulation of Positive_regulation of NOS2 14 0.47 11.15 4.3
111 INT89784 Regulation of Transcription of Nos2 14 0.42 8.39 4.24
112 INT70801 Gene_expression of Hmgcr 12 0.42 3.08 4.1
113 INT83991 Regulation of Nos3 25 0.44 9.89 4.06
114 INT33951 Regulation of TXNRD1 18 0.51 6.97 4.02
115 INT102515 Binding of Nos3 19 0.45 9.41 4.01
116 INT116349 Positive_regulation of Gene_expression of NDOR1 3 0.47 2.56 3.86
117 INT26233 Binding of GSR 45 0.46 18.22 3.74
118 INT35683 Gene_expression of Gsr 24 0.46 16.94 3.6
119 INT3842 Positive_regulation of Gsr 14 0.69 3.48 3.55
120 INT36142 Negative_regulation of Hmgcr 33 0.46 15.91 3.54
121 INT134875 Phosphorylation of Nos1 5 0.70 1.21 3.44
122 INT91070 Regulation of GSR 27 0.59 16.64 3.42
123 INT61952 Negative_regulation of Transcription of Nos2 17 0.54 5.1 3.34
124 INT60610 Negative_regulation of Gsr 7 0.26 6.88 3.32
125 INT271575 Gene_expression of MIOX 25 0.06 11.26 3.31
126 INT142568 Negative_regulation of Positive_regulation of Nos1 2 0.37 0.25 3.3
127 INT70958 Binding of NOS3 19 0.37 11.84 3.29
128 INT126223 Binding of Nos2 17 0.37 6 3.22
129 INT41312 Gene_expression of Gsr 13 0.44 4.62 3.18
130 INT116235 Negative_regulation of Transcription of Nos2 23 0.58 7.91 3.14
131 INT12948 Positive_regulation of Gene_expression of Cat 17 0.67 6.46 3.12
132 INT92814 Negative_regulation of NOS3 25 0.51 20.67 3.07
133 INT22944 Regulation of Grhpr 12 0.26 0.78 3
134 INT3644 Regulation of Grhpr 7 0.28 0.92 3
135 INT83351 Positive_regulation of Gene_expression of GSR 15 0.64 12.03 2.97
136 INT168604 Phosphorylation of Ndor1 1 0.68 0.75 2.97
137 INT89133 Transcription of NOS2 13 0.71 6.84 2.93
138 INT138652 Negative_regulation of Mthfr 13 0.54 7.3 2.88
139 INT5412 Regulation of G6pd 9 0.62 1.64 2.87
140 INT79722 Regulation of Cat 14 0.62 5.88 2.86
141 INT91869 Transcription of NOS3 13 0.67 6.81 2.86
142 INT85750 Regulation of Positive_regulation of Nos2 10 0.54 7.78 2.83
143 INT101883 Regulation of Gene_expression of Nos3 11 0.52 6.71 2.73
144 INT90675 Negative_regulation of Gene_expression of Nos3 15 0.46 11.11 2.7
145 INT57957 Localization of TXNRD1 14 0.64 4.01 2.7
146 INT49169 Regulation of Negative_regulation of Nos1 3 0.45 4.67 2.7
147 INT72757 Negative_regulation of Negative_regulation of Nos2 8 0.42 4.23 2.68
148 INT113892 Binding of Cat 6 0.48 3.95 2.65
149 INT108608 Positive_regulation of Positive_regulation of Nos1 8 0.49 1.66 2.58
150 INT97523 Phosphorylation of NOS1 3 0.46 0.59 2.58
151 INT89852 Localization of Nos2 22 0.78 14.89 2.56
152 INT124417 Gene_expression of Mthfr 8 0.60 8.65 2.53
153 INT145101 Transcription of Nos3 8 0.70 6.04 2.47
154 INT79609 Positive_regulation of Negative_regulation of Nos2 5 0.49 3.6 2.43
155 INT38384 Regulation of Por 5 0.47 0.58 2.4
156 INT22129 Positive_regulation of Gene_expression of CAT 11 0.67 4.23 2.37
157 INT76094 Localization of NOS2 8 0.72 2.76 2.34
158 INT165434 Regulation of SPR 4 0.24 2.14 2.33
159 INT73809 Regulation of Nos3 18 0.45 10.05 2.27
160 INT144792 Negative_regulation of Transcription of Nos1 2 0.43 1.74 2.27
161 INT79658 Transcription of GSR 8 0.68 3.59 2.19
162 INT132669 Positive_regulation of Transcription of NOS1 7 0.44 4.43 2.19
163 INT12131 Gene_expression of POR 17 0.77 9.42 2.17
164 INT141299 Negative_regulation of Gene_expression of Nos3 9 0.55 5.38 2.17
165 INT110016 Negative_regulation of Phosphorylation of Nos1 3 0.28 0.47 2.16
166 INT104263 Regulation of Positive_regulation of NOS1 5 0.28 3.15 2.15
167 INT121884 Regulation of Binding of Nos1 2 0.33 1.63 2.15
168 INT89130 Positive_regulation of Transcription of NOS2 7 0.50 3.32 2.14
169 INT127777 Positive_regulation of Mthfr 4 0.38 3.8 2.09
170 INT82166 Regulation of NOS3 14 0.54 7.57 2.08
171 INT13605 Localization of Me1 5 0.68 0.31 2.03
172 INT91594 Localization of NOS3 12 0.78 5.39 2.02
173 INT209439 Localization of Gsr 8 0.26 3.25 2
174 INT142049 Regulation of Mthfr 6 0.41 4.73 2
175 INT45723 Gene_expression of Grhpr 5 0.52 1.04 1.96
176 INT59302 Positive_regulation of POR 19 0.49 15.18 1.95
177 INT17890 Negative_regulation of HMGCR 26 0.42 12.05 1.94
178 INT58432 Positive_regulation of Gsr 12 0.70 9.4 1.94
179 INT110580 Regulation of Transcription of GSR 2 0.27 0.98 1.94
180 INT168605 Positive_regulation of Ndor1 2 0.57 0.43 1.89
181 INT76532 Binding of Nos3 13 0.37 9.32 1.87
182 INT123873 Positive_regulation of Negative_regulation of Cat 7 0.50 2.86 1.86
183 INT10724 Positive_regulation of Grhpr 6 0.31 0.6 1.78
184 INT60999 Localization of Nos3 12 0.74 5.28 1.75
185 INT107923 Regulation of Gene_expression of NOS3 11 0.61 2.73 1.73
186 INT79063 Regulation of Gene_expression of NOS2 6 0.43 3.68 1.7
187 INT64559 Positive_regulation of Negative_regulation of Nos1 2 0.41 1.58 1.68
188 INT97418 Regulation of Regulation of Nos1 2 0.41 0.94 1.68
189 INT168598 Negative_regulation of Phosphorylation of Ndor1 1 0.35 0.45 1.67
190 INT163666 Localization of Cat 8 0.80 5.84 1.57
191 INT181574 Phosphorylation of Nos2 9 0.70 2.92 1.55
192 INT46786 Positive_regulation of Positive_regulation of G6pd 3 0.47 0.47 1.52
193 INT152569 Positive_regulation of Gene_expression of NOX1 1 0.31 0.67 1.51
194 INT152560 Gene_expression of NOX1 3 0.49 0.73 1.49
195 INT12290 Gene_expression of Dhfr 7 0.76 2.04 1.47
196 INT96047 Positive_regulation of Localization of NOS1 6 0.38 4.24 1.47
197 INT181639 Positive_regulation of Positive_regulation of NOS3 8 0.41 3.72 1.41
198 INT61951 Regulation of Negative_regulation of Nos2 5 0.58 3.08 1.39
199 INT83713 Positive_regulation of Transcription of Nos3 3 0.67 2.92 1.38
200 INT89785 Regulation of Transcription of Nos3 1 0.32 0.85 1.36
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