GO:0050668

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Name positive regulation of homocysteine metabolic process
Categary Process
Go Slim No
Go Link GO:0050668
Unique Molecular Interactions 33
Total Molecular Interactions 44
Total Single Events 581
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of homocysteine metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of homocysteine metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT172203 Binding of Comt and Maoa 1 0.31 0.98 1.43
2 INT128913 Binding of COMT and PENK 1 0.30 0.07 1.41
3 INT128914 COMT Regulation of OPRM1 1 0.39 0.07 1.39
4 INT262377 Binding of Comt and Fmod 1 0.06 1.47 1.29
5 INT261617 SNRNP70 Regulation of Comt 1 0.01 0.4 1.18
6 INT265649 TBK1 Negative_regulation of COMT 1 0.01 0.61 0.94
7 INT165627 Binding of COMT and SLTM 1 0.09 0.86 0.88
8 INT202254 Binding of COMT and DRD2 1 0.41 0.23 0.86
9 INT282506 ocd Positive_regulation of Gene_expression of Comt 1 0.32 1.26 0.84
10 INT340115 Comt Regulation of Localization of Dusp1 1 0.12 0.83 0.83
11 INT340114 Comt Regulation of Localization of Pain1 1 0.02 0.83 0.83
12 INT340113 Comt Regulation of Bdnf 1 0.21 0.74 0.82
13 INT266100 Binding of COMT and SH2B2 1 0.25 1.22 0.74
14 INT327707 Binding of Comt and Drd1a 1 0.18 0.27 0.74
15 INT266108 Binding of COMT and HPS1 1 0.23 1.21 0.74
16 INT327702 Binding of Comt and Drd2 1 0.28 0.27 0.74
17 INT327712 Binding of Comt and Rbm39 1 0.00 0.27 0.74
18 INT287132 Binding of NT5E and Comt 1 0.03 0.11 0.73
19 INT167455 Binding of MSD and Comt 1 0.15 0.28 0.5
20 INT311616 Binding of MET and Comt 1 0.01 0.2 0.37
21 INT327701 Comt Regulation of Npcd 1 0.01 0 0.29
22 INT327706 Comt Regulation of Gopc 1 0.10 0 0.29
23 INT216040 Binding of Comt and Prodh 1 0.30 1.71 0.26
24 INT287131 Negative_regulation of Binding of NT5E and Comt 1 0.03 0.06 0.23
25 INT266103 Binding of COMT and SNRNP70 1 0.04 0.78 0.21
26 INT202252 COMT Regulation of DRD2 1 0.31 0 0.21
27 INT195423 COMT Negative_regulation of GBE1 1 0.00 0.22 0.19
28 INT327700 Binding of Comt and 4930579C15Rik 1 0.08 0 0.15
29 INT202253 Binding of COMT and TCN1 1 0.16 0 0.12
30 INT327703 Cish Regulation of Transcription of Comt 1 0.13 0.77 0.12
31 INT287130 Positive_regulation of Binding of NT5E and Comt 1 0.04 0 0.12
32 INT327709 Uts2r Positive_regulation of Comt 1 0.14 0.47 0.1
33 INT154023 Binding of NOVA2 and Comt 1 0.03 0.08 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of homocysteine metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of homocysteine metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT122953 Gene_expression of COMT 65 0.77 25.84 40.49
2 INT101120 Gene_expression of Comt 63 0.77 34.75 26.13
3 INT110638 Negative_regulation of COMT 43 0.59 21.03 21.05
4 INT519 Negative_regulation of Comt 52 0.59 17.65 20.39
5 INT135629 Binding of COMT 33 0.48 16.68 19.37
6 INT101119 Negative_regulation of Comt 19 0.58 8.77 13.09
7 INT17619 Regulation of COMT 12 0.45 8.46 12.22
8 INT520 Binding of Comt 24 0.48 8.98 12.21
9 INT144736 Negative_regulation of Gene_expression of COMT 13 0.58 6.47 9.28
10 INT122952 Positive_regulation of COMT 13 0.50 8.1 8.89
11 INT44537 Positive_regulation of Comt 7 0.69 2.62 7.78
12 INT101121 Regulation of Comt 19 0.53 10.66 7.22
13 INT144739 Regulation of Gene_expression of COMT 11 0.61 3.07 7.08
14 INT150825 Binding of Comt 13 0.42 6.65 6.42
15 INT50712 Gene_expression of Comt 13 0.68 6.33 6.23
16 INT2162 Regulation of Comt 13 0.60 2.9 5.18
17 INT2871 Positive_regulation of Comt 9 0.50 2.8 4.78
18 INT172197 Positive_regulation of Gene_expression of Comt 12 0.69 7.61 4.06
19 INT172198 Protein_catabolism of Comt 7 0.88 2.78 3.6
20 INT206598 Regulation of Gene_expression of Comt 9 0.60 6 3.56
21 INT195964 Transcription of Comt 8 0.71 4.72 3.4
22 INT194289 Transcription of COMT 3 0.72 3.56 2.72
23 INT202257 Localization of COMT 7 0.75 2.13 2.65
24 INT128983 Protein_catabolism of Comt 5 0.87 0.22 2.6
25 INT206593 Negative_regulation of Gene_expression of Comt 3 0.56 1.68 2.52
26 INT265662 Negative_regulation of Binding of COMT 4 0.37 1.29 2.42
27 INT136962 Protein_catabolism of COMT 4 0.89 1.12 2.14
28 INT447 Localization of Comt 4 0.75 0.76 1.8
29 INT265659 Positive_regulation of Negative_regulation of COMT 1 0.43 0.78 1.57
30 INT65165 Positive_regulation of Negative_regulation of Comt 1 0.03 0 1.15
31 INT246088 Negative_regulation of Negative_regulation of COMT 2 0.37 2.01 1
32 INT282479 Regulation of Protein_catabolism of Comt 2 0.45 1.17 0.85
33 INT265663 Positive_regulation of Gene_expression of COMT 2 0.50 0.26 0.79
34 INT195983 Localization of Comt 2 0.74 0.93 0.76
35 INT344931 Positive_regulation of Protein_catabolism of Comt 1 0.49 0 0.76
36 INT136963 Regulation of Protein_catabolism of COMT 1 0.24 0.49 0.72
37 INT265655 Regulation of Positive_regulation of COMT 1 0.39 0.38 0.49
38 INT327677 Regulation of Transcription of Comt 2 0.60 1.49 0.48
39 INT266128 Positive_regulation of Transcription of COMT 1 0.44 0.35 0.41
40 INT50711 Regulation of Gene_expression of Comt 2 0.01 0 0.39
41 INT266123 Negative_regulation of Transcription of COMT 1 0.59 0.65 0.3
42 INT287124 Negative_regulation of Protein_catabolism of Comt 1 0.38 0.22 0.29
43 INT266127 Regulation of Binding of COMT 1 0.39 0.54 0.27
44 INT287126 Negative_regulation of Negative_regulation of Comt 1 0.37 0.78 0.25
45 INT266124 Positive_regulation of Binding of COMT 1 0.44 0 0.23
46 INT266122 Regulation of Localization of COMT 1 0.39 0 0.21
47 INT327698 Regulation of Binding of Comt 1 0.39 0 0.2
48 INT327691 Negative_regulation of Transcription of Comt 1 0.37 0.33 0.18
49 INT327679 Regulation of Positive_regulation of Comt 1 0.39 0.39 0.17
50 INT209806 Transcription of Comt 1 0.69 2.12 0.11
51 INT266125 Regulation of Transcription of COMT 1 0.24 0.88 0.08
52 INT292012 Positive_regulation of Localization of COMT 1 0.44 0.13 0
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