GO:0050699

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Name WW domain binding
Categary Function
Go Slim No
Go Link GO:0050699
Unique Molecular Interactions 40
Total Molecular Interactions 51
Total Single Events 249
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for WW domain binding. They are ordered first by their pain relevance and then by number of times they were reported for WW domain binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT170832 Cftr Regulation of Scnn1a 2 0.16 1.2 0.67
2 INT151132 Negative_regulation of Map2k7 Negative_regulation of Gene_expression of Litaf 1 0.01 0.29 0.32
3 INT103147 Accn3 Regulation of Scnn1a 1 0.19 0.47 0.23
4 INT343850 Binding of TRAF4 and TICAM1 1 0.03 0.19 0.17
5 INT94864 Regulation of Litaf Positive_regulation of Nos2 1 0.05 0.05 0.15
6 INT94865 Litaf Positive_regulation of Nos2 1 0.08 0.05 0.15
7 INT317071 KCNC4 Regulation of SCNN1G 1 0.03 0.17 0.13
8 INT283539 Binding of Litaf and Mad2l1bp 1 0.00 0.67 0.11
9 INT196624 TNF Negative_regulation of Transcription of SCNN1G 1 0.02 0.07 0.07
10 INT179930 Litaf Positive_regulation of Ephb1 1 0.01 0.4 0.04
11 INT339569 VEGFA Positive_regulation of Litaf 1 0.18 0.6 0.04
12 INT179926 Litaf Positive_regulation of Ldha 1 0.01 0.4 0.04
13 INT179927 Litaf Positive_regulation of Mapk8 1 0.02 0.39 0.04
14 INT317072 SCNN1G Regulation of NA 1 0.00 0.08 0.04
15 INT196617 TNF Negative_regulation of Gene_expression of SCNN1G 1 0.02 0.08 0.03
16 INT196625 TNF Negative_regulation of Positive_regulation of SCNN1G 1 0.02 0.14 0.03
17 INT196607 IFNG Regulation of Gene_expression of SCNN1G 1 0.03 0.08 0.03
18 INT317075 Binding of NA and SCNN1G 1 0.00 0 0
19 INT325904 Binding of F2 and Wbp5 1 0.01 1.22 0
20 INT325910 Wbp5 Positive_regulation of Positive_regulation of F2 1 0.01 0.67 0
21 INT325900 Binding of Dio1 and Wbp5 1 0.00 0.25 0
22 INT329013 Binding of LITAF and Nedd4 1 0.15 1.4 0
23 INT317074 CA2 Regulation of SCNN1G 1 0.01 0.08 0
24 INT322931 Binding of MOCS1 and Litaf 1 0.00 0.82 0
25 INT325908 Binding of Wbp5 and Fgg 1 0.00 1.2 0
26 INT329008 Binding of LITAF and RNF123 1 0.01 1.39 0
27 INT325897 Negative_regulation of Binding of F2 and Wbp5 1 0.01 0.96 0
28 INT182400 E2F2 Regulation of CDC25C 1 0.00 0.09 0
29 INT325905 Wbp5 Positive_regulation of F2 1 0.01 0.37 0
30 INT329005 Binding of TSG101 and LITAF 1 0.04 1.41 0
31 INT182401 NFYA Regulation of CDC25C 1 0.00 0.09 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for WW domain binding. They are ordered first by their pain relevance and then by number of times they were reported in WW domain binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT94863 Gene_expression of Litaf 27 0.65 10.21 4.35
2 INT196687 Positive_regulation of SCNN1G 6 0.06 3.85 1.32
3 INT151126 Negative_regulation of Gene_expression of Litaf 6 0.32 2.48 1.21
4 INT120696 Gene_expression of SCNN1G 9 0.43 5.46 1.03
5 INT151130 Negative_regulation of Litaf 2 0.06 0.34 0.97
6 INT151122 Positive_regulation of Litaf 7 0.35 3.58 0.92
7 INT120697 Negative_regulation of SCNN1G 6 0.32 3.53 0.92
8 INT166006 Gene_expression of Scnn1a 2 0.46 0.32 0.83
9 INT151127 Regulation of Gene_expression of Litaf 3 0.18 2.1 0.72
10 INT144953 Localization of LITAF 2 0.02 1.75 0.68
11 INT179918 Negative_regulation of Binding of Litaf 1 0.02 2.52 0.66
12 INT209898 Gene_expression of TRAF4 1 0.52 2.11 0.64
13 INT151124 Localization of Litaf 2 0.10 2.03 0.57
14 INT204860 Positive_regulation of Litaf 2 0.67 1.83 0.51
15 INT78817 Binding of Scnn1a 2 0.35 0 0.48
16 INT217265 Positive_regulation of Gene_expression of Litaf 3 0.06 1.42 0.46
17 INT166007 Negative_regulation of Gene_expression of Scnn1a 1 0.26 0.32 0.46
18 INT23645 Regulation of Scnn1a 2 0.23 1.18 0.44
19 INT170830 Localization of Scnn1a 1 0.37 0.39 0.41
20 INT144954 Negative_regulation of Localization of LITAF 1 0.01 0.79 0.4
21 INT23646 Negative_regulation of Scnn1a 6 0.57 1.8 0.35
22 INT179921 Binding of Litaf 1 0.02 1.25 0.33
23 INT209903 Positive_regulation of TRAF4 1 0.41 1.27 0.28
24 INT103145 Positive_regulation of Scnn1a 1 0.21 0.47 0.24
25 INT179920 Regulation of Litaf 2 0.44 1.13 0.23
26 INT120694 Negative_regulation of Gene_expression of SCNN1G 3 0.32 2.08 0.19
27 INT15699 Binding of Litaf 2 0.01 1.06 0.19
28 INT179923 Negative_regulation of Localization of Litaf 1 0.02 0.85 0.19
29 INT317078 Regulation of SCNN1G 1 0.04 0.58 0.18
30 INT196671 Positive_regulation of Positive_regulation of SCNN1G 2 0.04 1.04 0.13
31 INT196674 Transcription of SCNN1G 1 0.04 0.22 0.1
32 INT196692 Positive_regulation of Gene_expression of SCNN1G 2 0.06 0.35 0.09
33 INT13218 Gene_expression of Litaf 2 0.52 0.8 0.09
34 INT120695 Regulation of Gene_expression of SCNN1G 1 0.22 0.77 0.08
35 INT196680 Negative_regulation of Positive_regulation of SCNN1G 1 0.04 0.28 0.07
36 INT179922 Phosphorylation of Litaf 1 0.03 0.39 0.04
37 INT179925 Negative_regulation of Phosphorylation of Litaf 1 0.02 0.39 0.04
38 INT317082 Positive_regulation of Negative_regulation of SCNN1G 1 0.04 0 0.03
39 INT325863 Localization of Wbp5 1 0.03 4.12 0.03
40 INT185333 Regulation of LITAF 1 0.09 0 0
41 INT325862 Negative_regulation of Wbp5 1 0.02 1.43 0
42 INT182436 Gene_expression of CDC25C 1 0.15 0.09 0
43 INT154855 Positive_regulation of Transcription of Litaf 1 0.13 0 0
44 INT325856 Positive_regulation of Wbp5 1 0.01 0.19 0
45 INT283538 Regulation of Gene_expression of Litaf 1 0.24 0.43 0
46 INT217268 Regulation of Positive_regulation of Litaf 1 0.04 0 0
47 INT317079 Negative_regulation of Binding of SCNN1G 1 0.04 0 0
48 INT325867 Gene_expression of Wbp5 1 0.03 2.15 0
49 INT325853 Binding of Wbp5 1 0.02 1.07 0
50 INT329762 Positive_regulation of CDC25C 1 0.22 0.82 0
51 INT317080 Binding of SCNN1G 1 0.03 0 0
52 INT329010 Protein_catabolism of LITAF 1 0.11 1.06 0
53 INT329772 Phosphorylation of CDC25C 1 0.28 0.81 0
54 INT154857 Transcription of Litaf 1 0.18 0 0
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