GO:0050715

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Name positive regulation of cytokine secretion
Categary Process
Go Slim No
Go Link GO:0050715
Unique Molecular Interactions 2162
Total Molecular Interactions 2931
Total Single Events 30897
Pain Genes Associated 40

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cytokine secretion. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of cytokine secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
2 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
3 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
4 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
5 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
6 INT150889 Il1a Regulation of Il10 1 0.22 3.49 2.95
7 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
8 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
9 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
10 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
11 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
12 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
13 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
14 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
15 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
16 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
17 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
18 INT155984 Il1a Negative_regulation of Gene_expression of Cyp3a11 1 0.24 0.92 2.2
19 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
20 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
21 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
22 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
23 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
24 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
25 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
26 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
27 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
28 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
29 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
30 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
31 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
32 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
33 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
34 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78
35 INT203149 Binding of Mif and Osm 1 0.02 2.93 1.78
36 INT149491 PNOC Negative_regulation of Gene_expression of CD14 1 0.40 0.37 1.76
37 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
38 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
39 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
40 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
41 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
42 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
43 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
44 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
45 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
46 INT41100 Mdk Positive_regulation of Localization of INS 1 0.01 0 1.55
47 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
48 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54
49 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
50 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
51 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
52 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
53 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
54 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
55 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
56 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
57 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
58 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
59 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
60 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
61 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
62 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
63 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
64 INT73597 Positive_regulation of BAX Positive_regulation of Casp1 1 0.06 0.69 1.28
65 INT73598 BAX Positive_regulation of Casp1 1 0.06 0.63 1.27
66 INT8409 IL1A Positive_regulation of Positive_regulation of Vip 1 0.01 0.63 1.27
67 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
68 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26
69 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
70 INT172141 IL10 Negative_regulation of Gene_expression of HLA-DRA 2 0.14 0.89 1.23
71 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23
72 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
73 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
74 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22
75 INT70036 LTA Regulation of Negative_regulation of IL10 1 0.03 1.42 1.21
76 INT70046 IL12A Regulation of IL10 1 0.07 1.42 1.21
77 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
78 INT70039 IL1B Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
79 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
80 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
81 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
82 INT70030 IL1B Regulation of IL10 1 0.07 1.42 1.21
83 INT70041 LTA Regulation of IL10 1 0.03 1.42 1.21
84 INT70034 IL12A Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
85 INT70029 IL6 Regulation of Negative_regulation of IL10 1 0.05 1.42 1.21
86 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2
87 INT131462 NGF Regulation of Localization of INS 1 0.40 0.97 1.2
88 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
89 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
90 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18
91 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
92 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
93 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
94 INT227324 Binding of fd and Cd14 1 0.01 2.8 1.13
95 INT72754 Adamts7 Negative_regulation of TNF 1 0.28 1.64 1.13
96 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
97 INT203103 ACAN Negative_regulation of Gene_expression of IL10 1 0.02 1.31 1.12
98 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12
99 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11
100 INT107264 Binding of TNF and NCR3 1 0.30 1.42 1.1
101 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
102 INT107266 Binding of HLA-DRB1 and TNF 1 0.29 1.41 1.1
103 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1
104 INT107267 Binding of HLA-A and TNF 1 0.34 1.41 1.1
105 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
106 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
107 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
108 INT76396 Il10 Negative_regulation of Il1b 2 0.65 1.89 1.08
109 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
110 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
111 INT119108 Binding of LTBR and TNF 2 0.15 1.47 1.07
112 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
113 INT292531 Il10 Negative_regulation of Positive_regulation of Mapk14 1 0.15 1.13 1.06
114 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05
115 INT8410 IL1A Positive_regulation of Vip 1 0.02 0.68 1.05
116 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05
117 INT152504 Binding of CR1 and Tnf 1 0.00 0.49 1.04
118 INT133650 Epo Negative_regulation of TNF 1 0.35 2.7 1.04
119 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03
120 INT156245 NFKB1 Positive_regulation of Regulation of TNF 1 0.45 0.76 1.03
121 INT81545 Tnf Positive_regulation of Gtf3a 2 0.03 1.41 1.02
122 INT182556 Ptger4 Positive_regulation of Ptgir 1 0.08 1.31 1.02
123 INT182567 Ptger4 Positive_regulation of Ptger1 1 0.15 1.31 1.02
124 INT352295 Binding of P2RY2 and Agtr1a 1 0.01 0.08 1.02
125 INT121743 Negative_regulation of Src Negative_regulation of Ephb1 1 0.27 0 1.02
126 INT317518 Src Regulation of Negative_regulation of Oprm1 1 0.16 0.07 1
127 INT308804 Pld1 Positive_regulation of TNF 1 0.05 2.42 0.99
128 INT228498 Il10 Negative_regulation of Hand1 1 0.03 1.4 0.99
129 INT143915 Src Regulation of Rbm39 1 0.03 0.18 0.99
130 INT274895 Positive_regulation of Cbr2 Negative_regulation of Gene_expression of TNF 1 0.06 1.21 0.99
131 INT129216 Negative_regulation of RYBP Positive_regulation of Tnf 1 0.01 1.24 0.98
132 INT182022 TNF Positive_regulation of Gene_expression of Tnfrsf11b 1 0.06 1.56 0.98
133 INT129215 RYBP Positive_regulation of Il10 1 0.01 1.24 0.98
134 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 0.43 0.61 0.98
135 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
136 INT292530 Il10 Negative_regulation of Localization of Il1a 1 0.06 1.09 0.97
137 INT40424 CCK Regulation of Localization of INS 1 0.02 0 0.97
138 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
139 INT159111 Il1a Regulation of Gene_expression of Il1b 1 0.49 0.38 0.97
140 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
141 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96
142 INT75283 SST Negative_regulation of Localization of INS 2 0.47 1.45 0.96
143 INT121744 Src Positive_regulation of Positive_regulation of Ephb1 1 0.35 0 0.96
144 INT133652 Epo Negative_regulation of Gene_expression of TNF 1 0.35 2.64 0.96
145 INT171264 TNF Positive_regulation of MMP1 2 0.10 2.05 0.95
146 INT188805 TNF Positive_regulation of Gene_expression of Crp 1 0.15 2.96 0.95
147 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
148 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94
149 INT129213 RYBP Positive_regulation of Gene_expression of Il10 1 0.01 1.04 0.94
150 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94
151 INT129211 RYBP Positive_regulation of Gene_expression of Tnf 1 0.01 1.04 0.94
152 INT227325 Binding of IRF6 and Cd14 1 0.01 2.51 0.93
153 INT155259 RUNX1 Negative_regulation of Tnf 1 0.00 1.48 0.93
154 INT145853 Casp1 Positive_regulation of Mapk14 1 0.02 0.68 0.93
155 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
156 INT165280 Tnf Positive_regulation of Gene_expression of Nos2 1 0.24 1.02 0.91
157 INT254242 TNF Positive_regulation of Gene_expression of DKK1 1 0.14 1.24 0.91
158 INT66536 Il1a Regulation of Gene_expression of Fos 1 0.59 0 0.91
159 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
160 INT78062 Il1a Positive_regulation of Localization of Il6 3 0.24 0.48 0.9
161 INT256646 Tnf Positive_regulation of Positive_regulation of Nfkb1 1 0.22 1.83 0.9
162 INT40636 Mif Negative_regulation of Pomc 1 0.25 0.07 0.9
163 INT343834 Binding of CD14 and IRF6 1 0.02 2.08 0.9
164 INT222988 TNF Positive_regulation of Protein_catabolism of COL1A1 1 0.01 1.66 0.9
165 INT211128 Binding of P4HB and TNF 1 0.09 0.97 0.9
166 INT211129 Negative_regulation of Binding of P4HB and TNF 1 0.10 0.97 0.9
167 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
168 INT80132 Binding of HLA-B and TNF 1 0.04 1.15 0.89
169 INT142278 Slc8a1 Regulation of Tnf 1 0.14 0.07 0.89
170 INT109103 MMP2 Positive_regulation of INS 1 0.33 1.07 0.89
171 INT21944 Il1a Negative_regulation of Gnrh1 1 0.34 0 0.89
172 INT167466 Ccdc80 Negative_regulation of Tnf 1 0.01 0.76 0.88
173 INT134311 Tnf Positive_regulation of Protein_catabolism of Nfkbia 1 0.18 0.57 0.88
174 INT253992 Cxcl12 Positive_regulation of Mif 1 0.46 1.31 0.88
175 INT151779 Calca Positive_regulation of Transcription of P2rx7 1 0.02 0.54 0.87
176 INT116556 Olr1627 Negative_regulation of Regulation of Tnf 1 0.01 1.52 0.87
177 INT203148 Mif Positive_regulation of Gene_expression of S100a8 1 0.00 1.56 0.87
178 INT249491 Efnb2 Positive_regulation of Phosphorylation of Src 1 0.01 0.5 0.87
179 INT97795 IRF6 Positive_regulation of Localization of TNF 3 0.09 1.57 0.86
180 INT152868 Tnf Regulation of Gene_expression of Trpv1 1 0.27 0.25 0.86
181 INT226337 Binding of IL10 and IL10RA 2 0.24 2.51 0.85
182 INT110315 Negative_regulation of ALOX5 Negative_regulation of Gene_expression of TNF 1 0.47 0.74 0.85
183 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
184 INT196638 TNF Positive_regulation of F2RL1 2 0.09 1.52 0.84
185 INT146919 Tnf Positive_regulation of Gene_expression of Ccl2 1 0.16 1.44 0.84
186 INT113237 Il10 Negative_regulation of Gene_expression of Tacr1 1 0.35 0.81 0.84
187 INT221034 IL10 Positive_regulation of Localization of CCL18 1 0.19 1.3 0.84
188 INT238641 Binding of TNF and Ifx 1 0.07 0.86 0.84
189 INT238642 Binding of TNF and Ada 1 0.03 0.86 0.84
190 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83
191 INT149626 Il1b Regulation of Gene_expression of Tnf 1 0.41 0.83 0.83
192 INT339293 Casp1 Regulation of Localization of Il1 1 0.07 1.87 0.83
193 INT102201 Tnf Regulation of Il1b 3 0.39 2.57 0.82
194 INT282129 Il10 Positive_regulation of Icam1 1 0.56 3.12 0.82
195 INT317513 Oprm1 Regulation of Positive_regulation of Src 1 0.09 0.4 0.82
196 INT317570 Oprm1 Regulation of Src 1 0.04 0.4 0.82
197 INT162071 Gene_expression of MC1R Negative_regulation of Gene_expression of TNF 1 0.41 0.34 0.82
198 INT66206 Negative_regulation of TNF Positive_regulation of NFKB1 2 0.53 1.71 0.81
199 INT187232 Vip Positive_regulation of Gene_expression of Il10 1 0.16 0.95 0.81
200 INT113239 Il10 Regulation of Transcription of Tacr1 1 0.45 0.79 0.81

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cytokine secretion. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of cytokine secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
3 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
4 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
5 INT6852 Localization of TNF 883 0.81 705.95 270.84
6 INT6481 Binding of TNF 624 0.48 510.2 214.82
7 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
8 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
9 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
10 INT812 Localization of INS 1026 0.81 515.6 145.31
11 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69
12 INT9660 Regulation of TNF 363 0.62 312.94 139.99
13 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52
14 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
15 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84
16 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01
17 INT10166 Localization of Tnf 237 0.81 153.95 88.64
18 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
19 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38
20 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
21 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
22 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
23 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
24 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72
25 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
26 INT251 Regulation of INS 398 0.62 232.47 55.04
27 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69
28 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
29 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43
30 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
31 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
32 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98
33 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5
34 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
35 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07
36 INT13354 Transcription of TNF 108 0.72 85.81 42.32
37 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52
38 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61
39 INT48896 Positive_regulation of Gene_expression of Il10 73 0.70 43.14 35.5
40 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
41 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79
42 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
43 INT52350 Gene_expression of CD14 184 0.75 71.37 33.13
44 INT35406 Localization of Tnf 94 0.81 64.63 31.65
45 INT90792 Localization of Il10 144 0.80 87.88 30.03
46 INT116737 Localization of Mif 63 0.81 52.97 28.11
47 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
48 INT5966 Localization of Il1a 50 0.78 22.91 26.54
49 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66
50 INT11746 Positive_regulation of Il1a 65 0.63 42.94 23.54
51 INT74423 Localization of IL10 91 0.80 61.6 22.95
52 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
53 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
54 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
55 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
56 INT86751 Negative_regulation of Il10 62 0.59 40.1 20.51
57 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28
58 INT69304 Negative_regulation of Il10 47 0.59 36.88 19.79
59 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
60 INT23787 Positive_regulation of P2rx7 36 0.68 23.54 19.45
61 INT74286 Regulation of Il10 42 0.44 28.06 19.44
62 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
63 INT16445 Gene_expression of IL1A 60 0.78 44.46 19.19
64 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
65 INT5967 Negative_regulation of Il1a 51 0.57 27.09 18.24
66 INT72564 Localization of Il10 41 0.78 28.62 17.6
67 INT48892 Transcription of Il10 31 0.71 27.26 16.77
68 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
69 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
70 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
71 INT68913 Gene_expression of Cd14 55 0.76 38.99 15.67
72 INT116736 Positive_regulation of Mif 40 0.70 31.93 15.37
73 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
74 INT10173 Binding of Tnf 45 0.48 35.6 14.32
75 INT79703 Gene_expression of Agtr1a 46 0.76 14.18 13.77
76 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
77 INT121241 Positive_regulation of P2rx7 65 0.69 40.94 13.59
78 INT14572 Binding of INS 205 0.48 175.43 13.38
79 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31
80 INT89842 Phosphorylation of Src 34 0.69 9.57 13.08
81 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83
82 INT2385 Gene_expression of MIF 57 0.68 40.74 12.78
83 INT86950 Negative_regulation of Gene_expression of Il10 26 0.42 18.92 12.73
84 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71
85 INT70050 Negative_regulation of IL10 56 0.58 37.45 12.39
86 INT60461 Positive_regulation of Gene_expression of Il1a 40 0.61 17.23 12.35
87 INT53038 Positive_regulation of Agtr1a 35 0.67 23.76 11.68
88 INT72949 Binding of Mif 31 0.46 23.12 11.65
89 INT19527 Negative_regulation of Gene_expression of Il1a 26 0.51 15.4 11.58
90 INT79835 Regulation of Il10 28 0.61 21.22 11.29
91 INT71766 Transcription of Il10 31 0.69 24.66 10.78
92 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75
93 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75
94 INT69035 Positive_regulation of Casp1 43 0.69 25.18 10.67
95 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64
96 INT135022 Gene_expression of Cd14 79 0.76 36.37 10.63
97 INT71768 Regulation of Gene_expression of Il10 27 0.62 19.17 10.4
98 INT71769 Negative_regulation of Gene_expression of Il10 40 0.57 22.53 10.37
99 INT10982 Negative_regulation of Agtr1a 42 0.58 22.42 10.29
100 INT81929 Negative_regulation of Gene_expression of IL10 41 0.57 27.99 9.87
101 INT73427 Localization of P2rx7 24 0.79 8.65 9.87
102 INT80110 Regulation of Positive_regulation of TNF 34 0.44 25.79 9.78
103 INT68960 Gene_expression of Ptger4 42 0.67 15.75 9.64
104 INT73497 Regulation of IL10 33 0.45 22.6 9.19
105 INT89845 Positive_regulation of Src 19 0.44 7.5 9.01
106 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
107 INT15768 Gene_expression of Il1a 20 0.71 9.31 8.78
108 INT117553 Regulation of MIF 10 0.56 12.76 8.67
109 INT53573 Negative_regulation of Localization of Tnf 19 0.59 11.57 8.54
110 INT70848 Gene_expression of Casp1 24 0.77 10.97 8.52
111 INT22481 Gene_expression of CADM1 28 0.65 30.26 8.5
112 INT48257 Negative_regulation of P2rx7 18 0.41 7.82 8.42
113 INT25152 Gene_expression of SAA1 37 0.75 53.56 8.07
114 INT99163 Positive_regulation of Cd14 18 0.49 16.02 7.91
115 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89
116 INT32210 Gene_expression of Mif 13 0.75 28.48 7.79
117 INT117543 Regulation of Gene_expression of CD14 21 0.59 6.66 7.67
118 INT49490 Positive_regulation of Transcription of TNF 19 0.70 14.76 7.58
119 INT19475 Positive_regulation of IL1A 20 0.67 17.99 7.57
120 INT4606 Regulation of Gene_expression of INS 67 0.61 54.69 7.53
121 INT69033 Negative_regulation of Casp1 21 0.58 13.15 7.52
122 INT68299 Binding of Tnf 17 0.39 12.55 7.49
123 INT103289 Binding of Il10 15 0.35 13.67 7.42
124 INT5308 Regulation of Il1a 17 0.44 10.8 7.31
125 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26
126 INT91906 Regulation of Gene_expression of Il10 13 0.58 8.92 7.06
127 INT72532 Regulation of Gene_expression of Il1a 13 0.54 4.91 6.71
128 INT117544 Regulation of CD14 24 0.45 5.85 6.66
129 INT517 Regulation of Mif 16 0.62 5.43 6.55
130 INT81586 Negative_regulation of Casp1 11 0.57 6.55 6.45
131 INT60527 Transcription of IL10 16 0.56 13.57 6.42
132 INT69985 Positive_regulation of Negative_regulation of TNF 21 0.50 13.26 6.31
133 INT23034 Positive_regulation of Il1a 15 0.70 8.75 6.29
134 INT90077 Gene_expression of Casp1 29 0.76 20.79 6.26
135 INT88326 Negative_regulation of P2rx7 16 0.58 8.77 6.25
136 INT94608 Regulation of P2rx7 19 0.23 8.06 6.19
137 INT68882 Binding of P2rx7 16 0.23 4.33 6.17
138 INT121370 Positive_regulation of MIF 22 0.70 17.79 6.08
139 INT516 Negative_regulation of Mif 13 0.59 6.69 6.08
140 INT172084 Positive_regulation of Binding of TNF 21 0.50 15.31 6.06
141 INT67060 Negative_regulation of Transcription of TNF 17 0.59 12.94 5.88
142 INT173974 Positive_regulation of Localization of Il10 25 0.68 16.81 5.87
143 INT71220 Positive_regulation of Casp1 15 0.38 10.23 5.84
144 INT135028 Positive_regulation of Cd14 34 0.59 16.19 5.73
145 INT6487 Positive_regulation of Positive_regulation of Tnf 21 0.56 16.06 5.64
146 INT58468 Negative_regulation of Gene_expression of IL1A 10 0.58 9.39 5.57
147 INT58145 Positive_regulation of Localization of Tnf 20 0.67 13.33 5.44
148 INT145680 Regulation of P2rx7 22 0.61 11.92 5.42
149 INT100222 Binding of Src 9 0.26 5.41 5.37
150 INT126751 Regulation of Gene_expression of IL10 16 0.44 10.84 5.22
151 INT301263 Gene_expression of Clec5a 22 0.77 14.64 5.18
152 INT58338 Negative_regulation of Localization of Il1a 8 0.25 3.13 5.18
153 INT170470 Binding of CD14 27 0.35 14.89 5.16
154 INT83442 Negative_regulation of MIF 18 0.57 9.51 5.12
155 INT69310 Negative_regulation of IL1A 10 0.43 7.83 5.05
156 INT92054 Positive_regulation of Transcription of Tnf 8 0.50 4.93 5.05
157 INT80712 Gene_expression of PTGER4 21 0.65 13.08 5.03
158 INT89844 Positive_regulation of Phosphorylation of Src 10 0.43 4.71 4.95
159 INT174339 Positive_regulation of Localization of Mif 7 0.61 8.27 4.95
160 INT88062 Gene_expression of Ptger4 13 0.77 2.4 4.94
161 INT100220 Negative_regulation of Src 13 0.41 6.37 4.93
162 INT142162 Binding of IL10 30 0.37 21.9 4.84
163 INT130290 Positive_regulation of Localization of IL10 16 0.47 9.38 4.75
164 INT55698 Regulation of Binding of TNF 13 0.44 8.98 4.74
165 INT121372 Positive_regulation of Gene_expression of MIF 17 0.60 14.78 4.73
166 INT71767 Positive_regulation of Transcription of Il10 10 0.67 5.55 4.66
167 INT98453 Positive_regulation of Src 19 0.47 7.84 4.62
168 INT92821 Positive_regulation of Gene_expression of Cd14 15 0.66 9.82 4.5
169 INT50309 Binding of Il1a 22 0.40 5.4 4.49
170 INT59083 Positive_regulation of Gene_expression of IL1A 11 0.70 9.09 4.48
171 INT88059 Positive_regulation of Ptger4 9 0.69 1.41 4.4
172 INT185484 Positive_regulation of Gene_expression of P2rx7 8 0.31 7.44 4.28
173 INT23035 Regulation of Il1a 6 0.60 5.69 4.25
174 INT97131 Positive_regulation of CD14 25 0.67 12.03 4.21
175 INT15462 Negative_regulation of Il1a 4 0.59 4.68 4.17
176 INT53040 Binding of Agtr1a 22 0.47 7.36 4.15
177 INT45975 Positive_regulation of SAA1 17 0.67 19.7 4.15
178 INT28983 Regulation of Htr2b 3 0.22 0.26 3.96
179 INT66754 Negative_regulation of Transcription of Tnf 11 0.43 8.43 3.93
180 INT144830 Positive_regulation of Gene_expression of P2rx7 22 0.68 9.78 3.92
181 INT89394 Phosphorylation of INS 37 0.82 35.84 3.9
182 INT23088 Phosphorylation of Tnf 15 0.79 9.85 3.82
183 INT116738 Positive_regulation of Gene_expression of Mif 14 0.68 10.99 3.8
184 INT172173 Protein_catabolism of TNF 16 0.96 9.95 3.79
185 INT19189 Localization of IL1A 14 0.78 9.02 3.78
186 INT25464 Binding of SAA1 11 0.42 6.89 3.72
187 INT194846 Positive_regulation of Positive_regulation of Il10 9 0.57 5.07 3.71
188 INT122327 Regulation of Src 6 0.59 0.59 3.6
189 INT74157 Negative_regulation of Positive_regulation of Il10 5 0.43 5.83 3.56
190 INT89521 Positive_regulation of Localization of Il10 8 0.44 6.45 3.51
191 INT194848 Negative_regulation of Localization of Il10 11 0.36 8.29 3.38
192 INT97138 Positive_regulation of Gene_expression of CD14 17 0.48 9.07 3.35
193 INT137350 Phosphorylation of Src 13 0.45 4.14 3.32
194 INT129441 Regulation of Gene_expression of P2rx7 8 0.24 4.29 3.32
195 INT48893 Positive_regulation of Transcription of Il10 3 0.69 4.29 3.29
196 INT174807 Gene_expression of IL26 7 0.37 8.06 3.26
197 INT185738 Binding of Cd14 28 0.45 14.41 3.25
198 INT119470 Regulation of Ptger4 6 0.43 3.94 3.24
199 INT65427 Regulation of Positive_regulation of Tnf 7 0.60 3.49 3.22
200 INT144828 Binding of P2rx7 19 0.47 7.84 3.16
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