GO:0050718

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Name positive regulation of interleukin-1 beta secretion
Categary Process
Go Slim No
Go Link GO:0050718
Unique Molecular Interactions 588
Total Molecular Interactions 758
Total Single Events 5658
Pain Genes Associated 30

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of interleukin-1 beta secretion. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of interleukin-1 beta secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT164362 Binding of NLRP1 and VTA1 1 0.15 2.37 4.67
2 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66
3 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
4 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
5 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
6 INT282398 Binding of Mefv and Nlrp3 1 0.40 6.8 1.72
7 INT114396 Positive_regulation of Vta1 Negative_regulation of Positive_regulation of Nlrp1a 1 0.03 0 1.63
8 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
9 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
10 INT92057 Ifng Positive_regulation of Gene_expression of Ik 1 0.03 0.45 1.49
11 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47
12 INT83626 Ifng Positive_regulation of Gene_expression of Cd59 1 0.33 2.19 1.41
13 INT160587 IFNG Positive_regulation of Gene_expression of OPRM1 1 0.18 0.54 1.35
14 INT73597 Positive_regulation of BAX Positive_regulation of Casp1 1 0.06 0.69 1.28
15 INT34052 POMC Regulation of Gene_expression of IFNG 1 0.11 0 1.27
16 INT73598 BAX Positive_regulation of Casp1 1 0.06 0.63 1.27
17 INT164365 Positive_regulation of Binding of NLRP1 and VTA1 1 0.14 0.6 1.21
18 INT122889 Ifng Positive_regulation of Gene_expression of HLA-E 1 0.02 0.97 1.1
19 INT113235 Tacr1 Regulation of Gene_expression of Ifng 1 0.26 1 1.04
20 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03
21 INT88875 Ifng Positive_regulation of Transcription of Nos2 1 0.02 0.27 1.03
22 INT88874 Ifng Regulation of Nos2 1 0.01 0.26 1.01
23 INT88879 Ifng Positive_regulation of Nfkb1 1 0.01 0.26 1.01
24 INT317836 Binding of Fibp and Pycard 1 0.00 2.68 0.98
25 INT94493 Avp Positive_regulation of Gene_expression of Ifng 1 0.05 1.73 0.97
26 INT275406 Binding of ITIH4 and Ccr5 1 0.09 2.88 0.97
27 INT275390 Binding of Ccr5 and Htatsf1 1 0.01 3.26 0.97
28 INT289173 PYCARD Regulation of MFGE8 1 0.05 0 0.96
29 INT77142 Binding of IFNG and IL4 2 0.03 1.16 0.95
30 INT145853 Casp1 Positive_regulation of Mapk14 1 0.02 0.68 0.93
31 INT94501 Il2 Positive_regulation of Gene_expression of Ifng 1 0.03 1.63 0.92
32 INT85879 Il12a Positive_regulation of Gene_expression of Ifng 1 0.20 0.89 0.92
33 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
34 INT91272 Ifng Positive_regulation of Localization of Il6 1 0.29 0 0.88
35 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
36 INT151779 Calca Positive_regulation of Transcription of P2rx7 1 0.02 0.54 0.87
37 INT181437 Binding of Ccr7 and Ccl21b 1 0.01 2.23 0.87
38 INT222243 Negative_regulation of Binding of Trpv1 and Ccr5 1 0.21 0.57 0.86
39 INT164363 Regulation of Binding of NLRP1 and VTA1 1 0.14 0.45 0.86
40 INT222244 Binding of Trpv1 and Ccr5 1 0.19 0.57 0.86
41 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
42 INT120999 Binding of Oprm1 and Ifng 1 0.22 0.57 0.84
43 INT339293 Casp1 Regulation of Localization of Il1 1 0.07 1.87 0.83
44 INT94331 IFNG Positive_regulation of CXCL10 4 0.11 1.31 0.82
45 INT339291 Casp1 Positive_regulation of Il1 2 0.12 1.63 0.8
46 INT81299 Ifng Positive_regulation of Gene_expression of Hmox1 1 0.52 0.75 0.76
47 INT142057 NLRP1 Regulation of Gene_expression of Fos 1 0.17 0 0.76
48 INT216668 Positive_regulation of NLRP1 Regulation of Vta1 1 0.00 0 0.73
49 INT146460 IFNG Positive_regulation of Gene_expression of TNFRSF10D 1 0.03 1.46 0.72
50 INT151679 Ifng Negative_regulation of Oas1b 1 0.12 1.24 0.71
51 INT146461 IFNG Positive_regulation of NFKB1 1 0.01 1.44 0.71
52 INT123494 Binding of Egr1 and Ccr5 1 0.04 0.94 0.71
53 INT151676 Ifng Negative_regulation of Art2a-ps 1 0.00 1.25 0.71
54 INT281241 Positive_regulation of P2RX7 Negative_regulation of Gene_expression of P2rx3 1 0.03 0.79 0.71
55 INT278812 PYCARD Positive_regulation of VTA1 1 0.09 0.11 0.71
56 INT120018 VEGFA Positive_regulation of CCL3 1 0.01 1 0.7
57 INT120017 CCL2 Positive_regulation of CCL3 1 0.01 0.99 0.7
58 INT205706 P2rx7 Regulation of Gene_expression of Il18 1 0.21 1.35 0.7
59 INT99818 IFNG Positive_regulation of Gene_expression of APP 1 0.04 0.82 0.7
60 INT120019 IL8 Positive_regulation of CCL3 1 0.02 0.99 0.7
61 INT246335 Fig4 Regulation of Localization of P2rx7 1 0.01 0 0.67
62 INT297307 Negative_regulation of Binding of Ccr1 and Ccl3 1 0.27 0.73 0.67
63 INT205702 P2rx7 Regulation of Gene_expression of Il1 1 0.04 1.38 0.67
64 INT103868 IFNG Positive_regulation of Hmox1 1 0.09 0.83 0.65
65 INT70161 Casp1 Regulation of Oprd1 1 0.03 0 0.65
66 INT70162 Casp1 Regulation of Penk 1 0.03 0 0.64
67 INT142076 IL4 Negative_regulation of Gene_expression of IFNG 1 0.01 1.58 0.64
68 INT56235 Ifng Positive_regulation of Gene_expression of RT1-EC2 1 0.23 0.33 0.62
69 INT128811 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Casp1 1 0.06 0.35 0.61
70 INT154530 Positive_regulation of Ifng Negative_regulation of Il10 1 0.33 0.63 0.61
71 INT66766 Casp1 Positive_regulation of Transcription of Pla2g10 1 0.06 0.19 0.6
72 INT179203 NLRP1 Regulation of Gene_expression of TNF 1 0.31 1.73 0.6
73 INT154533 Ifng Negative_regulation of Il4 1 0.11 0.62 0.6
74 INT154531 Ifng Negative_regulation of Il10 1 0.30 0.61 0.6
75 INT128604 Casp1 Positive_regulation of Gene_expression of Fos 1 0.10 0.55 0.59
76 INT56451 Ifng Positive_regulation of Tnf 1 0.00 1.92 0.59
77 INT87024 Positive_regulation of ZAK Positive_regulation of Localization of IFNG 2 0.05 0.81 0.58
78 INT205705 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of Il6 1 0.07 1.42 0.58
79 INT162789 Binding of TLR2 and NOD2 1 0.37 0.51 0.57
80 INT162790 Binding of TLR4 and NOD2 1 0.36 0.51 0.57
81 INT308174 Binding of TNF and P2rx7 1 0.02 0.84 0.56
82 INT244232 Binding of Ccr5 and Ccl4 3 0.17 1.48 0.55
83 INT339290 Casp1 Regulation of Gene_expression of Il1 1 0.11 1.38 0.55
84 INT221783 Nlrp1a Negative_regulation of Camk4 1 0.08 1.39 0.55
85 INT297311 Casp1 Positive_regulation of Il18 1 0.09 1.02 0.55
86 INT137162 IFNG Positive_regulation of Gene_expression of CXCL9 1 0.45 0.62 0.54
87 INT282821 TACR1 Regulation of P2RX7 1 0.01 2.06 0.54
88 INT88024 Ifng Positive_regulation of Gene_expression of Faslg 2 0.50 1.19 0.53
89 INT77098 Nlrp1a Negative_regulation of Positive_regulation of Ppig 1 0.47 0.68 0.53
90 INT185490 Atp5o Negative_regulation of Gene_expression of P2rx7 1 0.01 0.87 0.53
91 INT216941 P2rx7 Regulation of Ryr1 1 0.01 0.55 0.52
92 INT275387 Binding of Lamp1 and Ccr5 1 0.01 1.45 0.52
93 INT275405 Binding of GOLPH3 and Ccr5 1 0.00 1.46 0.52
94 INT138928 Ifng Positive_regulation of Transcription of Cxcl9 1 0.31 0.65 0.51
95 INT254356 Binding of IFNG and IL1B 1 0.00 1.87 0.51
96 INT143504 IFNG Positive_regulation of Gene_expression of Aif1 1 0.04 1.26 0.51
97 INT278122 Negative_regulation of P2rx7 Negative_regulation of Binding of P2RX7 1 0.03 0 0.51
98 INT278105 Negative_regulation of TP63 Negative_regulation of Binding of P2RX7 1 0.00 0 0.51
99 INT70925 Binding of Ifng and Il4 2 0.14 0.9 0.5
100 INT138927 Ifng Positive_regulation of Gene_expression of Stat1 1 0.29 0.7 0.49
101 INT150391 Binding of MEFV and PYCARD 4 0.14 3 0.48
102 INT142155 Ifng Positive_regulation of Il5 1 0.08 0 0.48
103 INT11651 Nlrp1a Negative_regulation of Gpt 1 0.12 0.24 0.47
104 INT338086 PYCARD Positive_regulation of TCEA1 1 0.10 0 0.47
105 INT196634 IFNG Negative_regulation of DNAH8 1 0.03 1.49 0.47
106 INT338083 Binding of LEFTY1 and PYCARD 1 0.02 0 0.46
107 INT275407 Binding of ERVW-1 and Ccr5 1 0.00 1.74 0.46
108 INT222284 Negative_regulation of Casp1 Negative_regulation of Il18 1 0.01 0.79 0.46
109 INT99790 Ifng Positive_regulation of Cxcr2 1 0.12 0.28 0.46
110 INT222283 Negative_regulation of Casp1 Negative_regulation of Il1a 1 0.00 0.78 0.46
111 INT181447 Ccl3 Positive_regulation of Csf2 1 0.06 1.89 0.45
112 INT316694 Binding of BLZF1 and Nlrp2 1 0.00 0.75 0.45
113 INT126337 Pax3 Positive_regulation of Gene_expression of Ifng 1 0.05 0.56 0.44
114 INT279360 ADA Negative_regulation of Gene_expression of IFNG 1 0.06 0.51 0.44
115 INT126340 Pax3 Regulation of Gene_expression of Ifng 1 0.03 0.56 0.44
116 INT126338 Insrr Regulation of Gene_expression of Ifng 1 0.00 0.56 0.43
117 INT146276 Binding of P2RX4 and P2RX7 1 0.38 0.38 0.43
118 INT36743 NLRP3 Regulation of Mbp 1 0.01 0 0.43
119 INT189154 MTNR1B Positive_regulation of Gene_expression of IFNG 1 0.01 0.06 0.43
120 INT90079 Ass1 Positive_regulation of Casp1 1 0.02 0.99 0.43
121 INT169859 P2rx7 Regulation of Gene_expression of Grin1 1 0.17 0 0.43
122 INT228323 PYCARD Positive_regulation of FIG4 1 0.17 0 0.42
123 INT210225 Ptpn2 Positive_regulation of Gene_expression of Ifng 1 0.15 1.44 0.42
124 INT17305 Ifng Positive_regulation of RT1-CE1 1 0.06 0.46 0.41
125 INT17308 Ifng Positive_regulation of Atp8a1 1 0.64 0.45 0.41
126 INT209918 Positive_regulation of Nlrp3 Positive_regulation of Localization of Il1 1 0.42 1.06 0.4
127 INT191493 Binding of AGTR1 and NLRP3 2 0.03 2.35 0.39
128 INT338085 Binding of PYCARD and GOPC 1 0.05 0 0.39
129 INT141016 Il18 Positive_regulation of Gene_expression of Ifng 1 0.39 0.27 0.39
130 INT278813 Binding of NOVA2 and PYCARD 1 0.13 0 0.38
131 INT123511 TIAF1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0.6 0.37
132 INT152361 Binding of Ifng and T2dm2 1 0.00 0.86 0.37
133 INT322015 Binding of IL1B and P2RX7 1 0.07 1 0.37
134 INT278389 Binding of Casp1 and Il1 2 0.09 0.82 0.36
135 INT140569 Ifng Positive_regulation of Gene_expression of Il6 1 0.00 0.82 0.36
136 INT179201 NLRP1 Regulation of Gene_expression of IL10 1 0.06 0.77 0.36
137 INT140571 Ifng Positive_regulation of Ifnb1 1 0.01 0.82 0.36
138 INT88192 IFNG Regulation of Gene_expression of ZAK 1 0.01 0.75 0.36
139 INT123495 Negative_regulation of Binding of Egr1 and Ccr5 1 0.03 0.48 0.36
140 INT152315 Ifng Regulation of Ednrb 1 0.19 0.22 0.36
141 INT123493 Regulation of Binding of Egr1 and Ccr5 1 0.03 0.48 0.36
142 INT140572 Ifng Positive_regulation of Gene_expression of Ifnb1 1 0.01 0.82 0.36
143 INT179202 NLRP1 Regulation of Gene_expression of IL6 1 0.07 0.77 0.36
144 INT140573 Positive_regulation of Ifng Positive_regulation of Ifnb1 1 0.01 0.83 0.36
145 INT187219 Vip Negative_regulation of Gene_expression of Ccl3 1 0.32 0.65 0.35
146 INT152316 Ifng Regulation of Edn1 1 0.01 0.22 0.35
147 INT144045 IFNG Negative_regulation of Gene_expression of PTGES 1 0.63 0.47 0.35
148 INT205704 P2rx7 Regulation of Localization of Il18 1 0.09 0.67 0.35
149 INT191128 Positive_regulation of P2RX7 Positive_regulation of Localization of Il1b 1 0.02 0.71 0.34
150 INT189492 Ifng Positive_regulation of Localization of Darc 1 0.00 0.53 0.34
151 INT140667 IFNG Regulation of Gene_expression of SLC6A4 1 0.40 0.41 0.34
152 INT217041 TNF Positive_regulation of Gene_expression of P2RX7 1 0.50 0.81 0.34
153 INT205713 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of IL8 1 0.03 0.77 0.33
154 INT217025 P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
155 INT112023 Binding of Ifng and Il10 1 0.03 0.31 0.33
156 INT112019 Binding of Ifng and Ighg1 1 0.10 0.3 0.33
157 INT217024 Regulation of P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
158 INT205703 P2rx7 Regulation of Positive_regulation of Casp1 1 0.11 0.66 0.33
159 INT205711 P2rx7 Regulation of Localization of IL8 1 0.02 0.92 0.33
160 INT325221 Il13 Regulation of Ccl3 1 0.08 0.17 0.32
161 INT189494 Negative_regulation of Ccr5 Negative_regulation of Gene_expression of Hand1 1 0.16 0.66 0.32
162 INT137168 IFNG Positive_regulation of Gene_expression of CXCR3 1 0.32 0.34 0.32
163 INT167596 Il23a Positive_regulation of Gene_expression of Ifng 1 0.13 0.94 0.32
164 INT349664 PYCARD Negative_regulation of Localization of AR 1 0.05 0 0.32
165 INT112022 Binding of Hand1 and Ifng 1 0.09 0.3 0.32
166 INT98013 Il18 Positive_regulation of Gene_expression of IFNG 1 0.66 0.44 0.32
167 INT349662 Binding of PYCARD and Negative_regulation of Localization of AR 1 0.05 0 0.32
168 INT289178 Regulation of PYCARD Regulation of MFGE8 1 0.05 0 0.32
169 INT145682 Binding of P2rx4 and P2rx7 2 0.25 0.36 0.31
170 INT284229 Binding of ITIH4 and Ccr5 1 0.10 0.27 0.31
171 INT317835 Nlrp3 Positive_regulation of Il18 1 0.08 1.49 0.31
172 INT289175 PYCARD Regulation of behavior 1 0.03 0 0.31
173 INT144500 CCL3 Positive_regulation of Gene_expression of Tnfsf11 1 0.77 1.62 0.31
174 INT191499 CMA1 Positive_regulation of NLRP3 1 0.02 0.42 0.3
175 INT191502 Binding of CMA1 and NLRP3 1 0.01 0.42 0.3
176 INT289179 PYCARD Regulation of TW 1 0.02 0 0.3
177 INT9161 Tnf Negative_regulation of Localization of Ifng 1 0.20 0.85 0.3
178 INT328407 Nlrp1a Negative_regulation of Gene_expression of Snca 1 0.07 0.31 0.29
179 INT93987 Positive_regulation of Rab8a Positive_regulation of Localization of Ifng 1 0.10 0.38 0.29
180 INT215789 Fig4 Positive_regulation of Localization of P2rx7 1 0.03 0.53 0.29
181 INT328410 Nlrp1a Negative_regulation of Snca 1 0.07 0.31 0.29
182 INT164432 Ifng Positive_regulation of Tnf 1 0.01 1.71 0.29
183 INT181446 Csf2 Positive_regulation of Ccl3 1 0.05 0.81 0.29
184 INT164431 Ifng Positive_regulation of Il6 1 0.01 1.71 0.29
185 INT191501 NLRP3 Positive_regulation of ECE1 1 0.01 1.09 0.28
186 INT191505 NLRP3 Positive_regulation of Protein_catabolism of EDN1 1 0.00 1.1 0.28
187 INT136368 RYBP Regulation of Localization of Ifng 1 0.00 0.4 0.28
188 INT171720 IL4 Positive_regulation of Positive_regulation of IFNG 1 0.01 0.67 0.28
189 INT279265 Binding of MEFV and NLRP3 1 0.07 2.79 0.28
190 INT207442 IFNG Negative_regulation of Gene_expression of PLA2G7 1 0.08 0.9 0.28
191 INT162599 Wnt5a Regulation of Gene_expression of IL4I1 1 0.00 0.1 0.28
192 INT191495 NLRP3 Positive_regulation of Protein_catabolism of ECE1 1 0.01 1.09 0.28
193 INT171726 TNF Positive_regulation of IFNG 1 0.01 0.6 0.27
194 INT219156 NLRP3 Positive_regulation of IL1B 1 0.01 1.03 0.27
195 INT191497 Binding of REN and NLRP3 1 0.02 0.55 0.27
196 INT171725 IFNG Positive_regulation of CXCL9 1 0.02 0.6 0.27
197 INT93352 Ifng Positive_regulation of Positive_regulation of Fas 1 0.26 0.17 0.27
198 INT137167 Binding of IFNG and TLR3 1 0.24 0.32 0.27
199 INT191504 CPN2 Positive_regulation of NLRP3 1 0.00 0.37 0.27
200 INT219194 Nlrp3 Positive_regulation of IL1B 1 0.04 1.03 0.26

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of interleukin-1 beta secretion. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of interleukin-1 beta secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57
2 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14
3 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6
4 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
5 INT56224 Negative_regulation of Gene_expression of Ifng 40 0.58 23.34 25.08
6 INT43486 Positive_regulation of Ifng 52 0.69 32.71 24.77
7 INT151758 Gene_expression of PYCARD 91 0.63 14.54 24.27
8 INT8518 Localization of Ifng 53 0.81 36.68 24.13
9 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05
10 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
11 INT25222 Positive_regulation of Gene_expression of Ifng 32 0.50 24.18 19.58
12 INT23787 Positive_regulation of P2rx7 36 0.68 23.54 19.45
13 INT19509 Localization of Ifng 55 0.78 28.25 18.67
14 INT35086 Positive_regulation of Gene_expression of Ifng 40 0.69 22.55 18.35
15 INT167679 Gene_expression of Ccr5 74 0.75 59.03 18.16
16 INT71680 Gene_expression of CCL3 43 0.75 33.7 18.01
17 INT24209 Negative_regulation of Ifng 37 0.57 16.52 17.15
18 INT164366 Localization of NLRP1 26 0.71 5.9 16.54
19 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89
20 INT114395 Positive_regulation of Nlrp1a 15 0.45 4.61 15.37
21 INT10360 Positive_regulation of Ifng 33 0.68 21.73 15.19
22 INT127046 Gene_expression of P2RX7 65 0.78 34.28 14.76
23 INT4931 Localization of IFNG 53 0.78 33.25 13.65
24 INT121241 Positive_regulation of P2rx7 65 0.69 40.94 13.59
25 INT20376 Gene_expression of Ccl3 39 0.75 45.42 13.15
26 INT7532 Negative_regulation of Gene_expression of Ifng 33 0.59 18.56 13.14
27 INT5057 Negative_regulation of Gene_expression of IFNG 23 0.58 8.33 12.3
28 INT145425 Positive_regulation of NLRP1 19 0.47 6.93 12.09
29 INT9160 Negative_regulation of Ifng 31 0.58 16.37 11.84
30 INT19944 Negative_regulation of IFNG 39 0.58 22.35 10.91
31 INT69035 Positive_regulation of Casp1 43 0.69 25.18 10.67
32 INT128364 Positive_regulation of Ccl3 20 0.70 23.96 10.65
33 INT87393 Gene_expression of Ccr5 19 0.65 11 10.51
34 INT137980 Positive_regulation of P2RX7 30 0.67 22.49 10
35 INT73427 Localization of P2rx7 24 0.79 8.65 9.87
36 INT35707 Gene_expression of Nlrp1a 20 0.75 9.61 9.32
37 INT70848 Gene_expression of Casp1 24 0.77 10.97 8.52
38 INT48257 Negative_regulation of P2rx7 18 0.41 7.82 8.42
39 INT97516 Binding of PYCARD 46 0.36 7.06 7.85
40 INT69033 Negative_regulation of Casp1 21 0.58 13.15 7.52
41 INT114394 Negative_regulation of Positive_regulation of Nlrp1a 4 0.42 1.09 7.37
42 INT103909 Gene_expression of NOD2 37 0.77 21.9 7.36
43 INT5326 Regulation of Ifng 12 0.55 4.56 7.19
44 INT153271 Localization of Ccl3 7 0.81 11.29 7.14
45 INT153268 Positive_regulation of Ccr5 25 0.66 19 7.02
46 INT1766 Negative_regulation of PYCARD 25 0.37 6.54 6.76
47 INT206603 Localization of Nlrp1a 9 0.16 1.37 6.57
48 INT23174 Gene_expression of NLRP3 51 0.72 35.49 6.47
49 INT81586 Negative_regulation of Casp1 11 0.57 6.55 6.45
50 INT90077 Gene_expression of Casp1 29 0.76 20.79 6.26
51 INT88326 Negative_regulation of P2rx7 16 0.58 8.77 6.25
52 INT74154 Transcription of Ifng 14 0.67 10.33 6.21
53 INT94608 Regulation of P2rx7 19 0.23 8.06 6.19
54 INT137052 Positive_regulation of PYCARD 30 0.43 4.72 6.17
55 INT68882 Binding of P2rx7 16 0.23 4.33 6.17
56 INT17641 Gene_expression of NLRP1 33 0.73 8.85 6.02
57 INT15803 Regulation of IFNG 21 0.44 12.57 5.98
58 INT120089 Negative_regulation of Ccr5 7 0.58 10.36 5.91
59 INT5186 Regulation of Ifng 11 0.45 8.78 5.9
60 INT71220 Positive_regulation of Casp1 15 0.38 10.23 5.84
61 INT103847 Positive_regulation of Ccr5 11 0.55 6.04 5.79
62 INT181406 Binding of Ccr5 16 0.45 17 5.78
63 INT166765 Localization of PYCARD 21 0.70 3.89 5.66
64 INT145680 Regulation of P2rx7 22 0.61 11.92 5.42
65 INT166878 Regulation of Ccl3 9 0.44 8.21 4.81
66 INT62132 Regulation of Gene_expression of Ifng 12 0.62 1.28 4.77
67 INT153269 Binding of Ccl3 10 0.48 8.87 4.69
68 INT36221 Positive_regulation of Nlrp3 25 0.68 19.7 4.5
69 INT133231 Regulation of PYCARD 18 0.39 5.02 4.44
70 INT99020 Gene_expression of Nlrp3 23 0.75 18.86 4.4
71 INT185484 Positive_regulation of Gene_expression of P2rx7 8 0.31 7.44 4.28
72 INT166966 Gene_expression of Ccr7 14 0.48 7.36 4.2
73 INT79234 Positive_regulation of CCL3 15 0.67 11.43 4.15
74 INT127047 Negative_regulation of P2RX7 10 0.39 7.17 4.01
75 INT144830 Positive_regulation of Gene_expression of P2rx7 22 0.68 9.78 3.92
76 INT103843 Positive_regulation of Gene_expression of Ccr5 5 0.42 2.31 3.89
77 INT144083 Positive_regulation of Gene_expression of Ccl3 10 0.50 8.16 3.81
78 INT108481 Positive_regulation of CCL19 4 0.44 15.22 3.77
79 INT34054 Regulation of Gene_expression of IFNG 8 0.42 3.69 3.76
80 INT108484 Gene_expression of CCL19 4 0.50 12.56 3.63
81 INT125622 Regulation of NLRP1 7 0.44 1.84 3.62
82 INT15982 Positive_regulation of NLRP3 25 0.65 23.19 3.57
83 INT181357 Negative_regulation of Ccl3 12 0.59 13.09 3.38
84 INT87027 Positive_regulation of Localization of IFNG 12 0.67 5.78 3.35
85 INT129441 Regulation of Gene_expression of P2rx7 8 0.24 4.29 3.32
86 INT156268 Regulation of Nlrp1a 4 0.08 1.95 3.18
87 INT144828 Binding of P2rx7 19 0.47 7.84 3.16
88 INT166879 Localization of Ccr5 4 0.71 3.62 2.97
89 INT191120 Regulation of P2RX7 8 0.41 5.29 2.96
90 INT103910 Binding of NOD2 19 0.47 12.24 2.93
91 INT137978 Localization of P2RX7 6 0.73 5.04 2.84
92 INT67078 Binding of Ifng 7 0.48 4.84 2.73
93 INT15197 Regulation of Gene_expression of Ifng 8 0.34 2.66 2.69
94 INT107433 Localization of Casp1 6 0.56 2.44 2.64
95 INT107216 Negative_regulation of Gene_expression of P2rx7 10 0.56 3.39 2.61
96 INT111145 Negative_regulation of Positive_regulation of Ifng 7 0.41 2.21 2.61
97 INT87395 Binding of Ccr5 5 0.29 2.5 2.6
98 INT257950 Regulation of Localization of NLRP1 3 0.08 0.27 2.6
99 INT156876 Positive_regulation of Gene_expression of Casp1 10 0.50 10.25 2.58
100 INT91669 Negative_regulation of Localization of IFNG 5 0.57 4.1 2.58
101 INT164367 Negative_regulation of Localization of NLRP1 3 0.34 1.43 2.5
102 INT16964 Binding of IFNG 27 0.48 14.31 2.45
103 INT205692 Positive_regulation of Positive_regulation of Casp1 5 0.46 3 2.44
104 INT71681 Positive_regulation of Gene_expression of CCL3 8 0.54 8.21 2.41
105 INT73980 Transcription of Ifng 12 0.72 5.42 2.4
106 INT70918 Positive_regulation of Localization of Ifng 5 0.45 2.79 2.33
107 INT67437 Negative_regulation of Localization of Ifng 7 0.47 2.23 2.28
108 INT10612 Localization of NLRP3 13 0.78 8.91 2.27
109 INT181356 Positive_regulation of Gene_expression of Ccr5 11 0.66 8.3 2.24
110 INT137972 Binding of P2RX7 12 0.36 8.01 2.18
111 INT112784 Positive_regulation of Positive_regulation of IFNG 11 0.49 7.84 2.18
112 INT96743 Transcription of Ccr5 2 0.54 2.72 2.17
113 INT92260 Binding of Nlrp3 14 0.46 8.94 2.13
114 INT144829 Localization of P2rx7 12 0.79 2.92 2.12
115 INT140818 Positive_regulation of Positive_regulation of Ifng 2 0.47 4.2 2.06
116 INT142056 Binding of NLRP1 7 0.47 1.7 2.02
117 INT131920 Positive_regulation of Gene_expression of Nlrp1a 4 0.08 2.23 2.02
118 INT111530 Positive_regulation of Regulation of Ifng 1 0.41 0.32 2.01
119 INT24453 Binding of NLRP3 18 0.48 13.7 1.93
120 INT11136 Positive_regulation of Localization of Ifng 4 0.49 3.13 1.89
121 INT216936 Negative_regulation of Gene_expression of P2rx7 5 0.42 2.59 1.84
122 INT117221 Positive_regulation of Gene_expression of NOD2 7 0.65 4.39 1.83
123 INT61627 Transcription of IFNG 6 0.69 4.28 1.83
124 INT264622 Regulation of Positive_regulation of Nlrp1a 1 0.02 0 1.83
125 INT120014 Transcription of CCL3 5 0.69 3.03 1.82
126 INT108486 Positive_regulation of Gene_expression of CCL19 2 0.45 6.2 1.79
127 INT162793 Regulation of NOD2 6 0.45 7.61 1.78
128 INT206592 Negative_regulation of Localization of Nlrp1a 2 0.06 0.47 1.75
129 INT87394 Negative_regulation of Ccr5 3 0.32 1.3 1.74
130 INT141385 Positive_regulation of Gene_expression of P2RX7 7 0.62 3.95 1.73
131 INT113716 Positive_regulation of Transcription of Ifng 1 0.53 2.56 1.61
132 INT23786 Positive_regulation of Positive_regulation of P2rx7 5 0.44 2.21 1.58
133 INT126759 Negative_regulation of Nlrp3 5 0.41 2.95 1.58
134 INT125735 Transcription of P2rx7 3 0.62 1.34 1.58
135 INT264620 Positive_regulation of Localization of Nlrp1a 1 0.04 0.59 1.54
136 INT23171 Negative_regulation of NLRP3 7 0.37 4.15 1.53
137 INT216666 Positive_regulation of Localization of NLRP1 2 0.09 0.5 1.49
138 INT215757 Transcription of P2rx7 3 0.21 1.84 1.45
139 INT205691 Regulation of Gene_expression of P2rx7 5 0.44 3.25 1.42
140 INT56228 Positive_regulation of Positive_regulation of Ifng 2 0.43 2.83 1.4
141 INT69034 Regulation of Casp1 3 0.27 3.56 1.36
142 INT117219 Positive_regulation of NOD2 9 0.69 4.66 1.31
143 INT205690 Positive_regulation of Positive_regulation of P2rx7 14 0.68 6.26 1.3
144 INT204766 Gene_expression of Nod2 4 0.75 4.14 1.3
145 INT96073 Localization of Casp1 11 0.78 4.91 1.29
146 INT73590 Positive_regulation of Positive_regulation of Casp1 2 0.19 1.94 1.28
147 INT11137 Negative_regulation of Localization of Ifng 3 0.38 2.45 1.26
148 INT65699 Localization of CCL3 7 0.78 2.56 1.25
149 INT19923 Regulation of Localization of Ifng 3 0.22 1.1 1.25
150 INT123828 Regulation of CCL3 3 0.60 0.79 1.25
151 INT206595 Negative_regulation of Nlrp1a 1 0.06 0.5 1.25
152 INT228328 Positive_regulation of Gene_expression of PYCARD 7 0.34 0.27 1.23
153 INT109243 Regulation of Positive_regulation of IFNG 1 0.45 1.27 1.23
154 INT267652 Negative_regulation of Gene_expression of PYCARD 6 0.37 2.35 1.22
155 INT111536 Positive_regulation of Negative_regulation of Ifng 1 0.41 0.35 1.18
156 INT150074 Gene_expression of WNT5A 8 0.75 6.3 1.17
157 INT191527 Positive_regulation of Gene_expression of NLRP3 6 0.50 8.65 1.15
158 INT152010 Positive_regulation of Ccr7 3 0.47 1.46 1.15
159 INT153267 Negative_regulation of Binding of Ccl3 2 0.43 2.06 1.14
160 INT181410 Regulation of Gene_expression of Ccl3 2 0.33 3.52 1.06
161 INT209912 Gene_expression of Pycard 17 0.22 12.04 1.04
162 INT122884 Positive_regulation of Transcription of Ifng 1 0.39 1.08 1.03
163 INT267750 Binding of Casp1 4 0.35 1.53 1.02
164 INT307280 Regulation of Gene_expression of PYCARD 2 0.39 0.27 1.02
165 INT181354 Binding of Ccr7 2 0.23 1.94 1.01
166 INT166880 Negative_regulation of Gene_expression of Ccl3 1 0.57 0.81 1.01
167 INT169319 Regulation of Gene_expression of Nlrp1a 2 0.60 0.31 1
168 INT216661 Regulation of Positive_regulation of P2rx7 1 0.07 0 1
169 INT191121 Regulation of Gene_expression of P2RX7 3 0.36 3.69 0.99
170 INT154227 Regulation of Gene_expression of NOD2 3 0.44 3.38 0.99
171 INT113887 Positive_regulation of Negative_regulation of P2rx7 1 0.22 1.02 0.96
172 INT278350 Regulation of Nlrp3 3 0.38 2.8 0.95
173 INT219135 Positive_regulation of Gene_expression of Nlrp3 4 0.49 3.52 0.93
174 INT215567 Positive_regulation of Positive_regulation of P2RX7 2 0.45 0.07 0.93
175 INT87396 Negative_regulation of Gene_expression of Ccr5 1 0.12 1.02 0.92
176 INT202174 Negative_regulation of CCL3 2 0.26 1.77 0.9
177 INT115238 Positive_regulation of Gene_expression of Casp1 5 0.68 1.78 0.88
178 INT79235 Binding of CCL3 3 0.36 2.2 0.88
179 INT96074 Negative_regulation of Gene_expression of Casp1 4 0.57 2.77 0.87
180 INT189482 Regulation of Gene_expression of Ccr5 4 0.44 3.38 0.86
181 INT151776 Positive_regulation of Transcription of P2rx7 1 0.03 0.53 0.86
182 INT35706 Protein_catabolism of Nlrp1a 1 0.52 0.07 0.84
183 INT103303 Negative_regulation of Transcription of Ifng 6 0.43 2.7 0.83
184 INT160410 Positive_regulation of Positive_regulation of Ccr5 2 0.38 1.31 0.83
185 INT43488 Regulation of Positive_regulation of Ifng 1 0.42 0.71 0.83
186 INT64635 Binding of Ifng 2 0.36 0.57 0.81
187 INT228326 Positive_regulation of Localization of PYCARD 3 0.41 0 0.8
188 INT153272 Positive_regulation of Localization of Ccl3 2 0.50 2.02 0.79
189 INT205685 Regulation of Positive_regulation of Casp1 3 0.11 1.62 0.78
190 INT271589 Regulation of Transcription of P2rx7 1 0.05 0.5 0.78
191 INT278119 Positive_regulation of Localization of P2RX7 2 0.45 1.14 0.77
192 INT11138 Regulation of Localization of Ifng 2 0.56 0.8 0.77
193 INT73240 Negative_regulation of Transcription of IFNG 1 0.41 0.92 0.76
194 INT182049 Protein_catabolism of Casp1 3 0.20 1.64 0.73
195 INT163783 Transcription of Casp1 1 0.58 0.88 0.73
196 INT163785 Positive_regulation of Transcription of Casp1 1 0.42 0.89 0.73
197 INT120013 Negative_regulation of Transcription of CCL3 1 0.41 1 0.72
198 INT70156 Regulation of Casp1 2 0.15 0.79 0.7
199 INT153270 Positive_regulation of Binding of Ccl3 1 0.47 1.44 0.69
200 INT138237 Negative_regulation of Negative_regulation of Casp1 1 0.30 0.56 0.69
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