GO:0050730

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Name regulation of peptidyl-tyrosine phosphorylation
Categary Process
Go Slim No
Go Link GO:0050730
Unique Molecular Interactions 717
Total Molecular Interactions 979
Total Single Events 7015
Pain Genes Associated 24

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of peptidyl-tyrosine phosphorylation. They are ordered first by their pain relevance and then by number of times they were reported for regulation of peptidyl-tyrosine phosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT169218 Binding of EGFR and Coc 1 0.06 2.8 5.85
2 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
3 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
4 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 0.38 0.86 2.63
5 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52
6 INT147659 Prkce Positive_regulation of TRPV1 1 0.04 1.42 2.43
7 INT121216 Prkca Regulation of Positive_regulation of Oprd1 1 0.02 0.32 2.02
8 INT135582 Prok2 Positive_regulation of Localization of Prkce 1 0.06 1.02 1.87
9 INT169468 Binding of Egfr and Spink3 1 0.37 3.73 1.83
10 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
11 INT167765 Prkca Positive_regulation of Sigmar1 1 0.41 0.63 1.74
12 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
13 INT139433 Binding of Prkaca and Prkca 1 0.37 0.13 1.67
14 INT81709 POMC Regulation of Gene_expression of ITGB2 1 0.40 0.34 1.57
15 INT81715 POMC Regulation of ITGB2 1 0.40 0.34 1.55
16 INT136844 Binding of Prkca and Nrgn 1 0.33 0 1.47
17 INT221242 Ros1 Positive_regulation of Prkca 1 0.02 0.39 1.44
18 INT169297 TRPV1 Positive_regulation of EGFR 1 0.64 0.37 1.3
19 INT169289 CNR1 Positive_regulation of EGFR 1 0.62 0.36 1.28
20 INT271602 Binding of Pdgfa and Pdgfrl 1 0.02 0.86 1.25
21 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
22 INT204558 Tens1 Negative_regulation of Pdgfc 1 0.01 0.25 1.2
23 INT220751 EGF Regulation of GOPC 1 0.08 0 1.18
24 INT220752 Negative_regulation of EGF Regulation of NAV1 1 0.26 0 1.18
25 INT220753 Negative_regulation of EGF Regulation of GOPC 1 0.08 0 1.18
26 INT150835 Gper Positive_regulation of Localization of Prkce 1 0.15 0.62 1.18
27 INT220748 EGF Regulation of NAV1 1 0.28 0 1.17
28 INT147660 Positive_regulation of Prkce Positive_regulation of TRPV1 1 0.04 0.69 1.12
29 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
30 INT136989 EGF Negative_regulation of Positive_regulation of KCNJ2 1 0.04 1.09 1.1
31 INT317512 Binding of Oprm1 and Prkca 1 0.07 0.13 1.1
32 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07
33 INT96905 Plxna3 Regulation of Regulation of Prkce 1 0.18 0.71 1.07
34 INT136988 EGF Negative_regulation of KCNJ2 1 0.04 1.09 1.04
35 INT317568 Prkca Regulation of Negative_regulation of Oprm1 1 0.10 0.07 1
36 INT211745 Gnptab Regulation of Positive_regulation of Prkca 1 0.00 0 0.96
37 INT123051 Gpbar1 Regulation of Phosphorylation of Prkca 1 0.43 0 0.94
38 INT123050 Prkca Regulation of Phosphorylation of Grk4 1 0.33 0 0.94
39 INT123048 Grk4 Regulation of Phosphorylation of Prkca 1 0.33 0 0.94
40 INT123053 Prkca Regulation of Phosphorylation of Gpbar1 1 0.43 0 0.94
41 INT72386 Egf Positive_regulation of Phosphorylation of Shc1 1 0.09 0.18 0.93
42 INT161455 Mmp7 Positive_regulation of Egfr 1 0.03 0.19 0.92
43 INT169469 Binding of Egfr and Tgfa 1 0.19 1.87 0.91
44 INT109842 Prkce Positive_regulation of Localization of Trpv1 1 0.13 1.31 0.91
45 INT271601 Pdgfa Positive_regulation of Pdgfrl 1 0.03 0.83 0.91
46 INT118288 EGF Positive_regulation of Phosphorylation of EGFR 9 0.54 3.85 0.9
47 INT220744 EGF Positive_regulation of Gene_expression of KRT20 1 0.01 1.26 0.9
48 INT167771 Prkca Positive_regulation of Phosphorylation of Sigmar1 1 0.38 0.23 0.89
49 INT134454 EGF Positive_regulation of EGFR 3 0.56 1.32 0.88
50 INT134453 Negative_regulation of EGF Positive_regulation of EGFR 1 0.35 0.35 0.88
51 INT317515 Binding of Hint1 and Prkca 1 0.13 0.17 0.87
52 INT220739 EGF Positive_regulation of Transcription of NAV1 1 0.31 0.16 0.83
53 INT317546 Oprm1 Regulation of Prkca 1 0.06 0.4 0.82
54 INT117341 ADAM17 Positive_regulation of EGFR 1 0.16 3.56 0.82
55 INT190869 Binding of Prkca and Ltp 1 0.03 0.86 0.81
56 INT157915 Prkca Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
57 INT84039 EGF Positive_regulation of Gene_expression of CPOX 2 0.11 1.88 0.8
58 INT84040 EGF Positive_regulation of CPOX 2 0.07 1.91 0.8
59 INT322397 Egfr Positive_regulation of Adarb1 1 0.00 0.08 0.8
60 INT282063 Ngf Positive_regulation of Positive_regulation of Prkca 1 0.09 0.18 0.8
61 INT220747 Binding of PCa and EGF 1 0.05 1.42 0.8
62 INT42797 Egf Regulation of Gene_expression of Penk 1 0.21 0.07 0.8
63 INT108331 EGF Positive_regulation of Phosphorylation of BAD 1 0.49 6.72 0.8
64 INT262579 Ngf Positive_regulation of Prkca 1 0.07 0.36 0.8
65 INT81716 ITGAL Regulation of ITGB2 2 0.30 1.24 0.78
66 INT261834 Itpr3 Positive_regulation of Prkca 2 0.01 0.33 0.78
67 INT110518 Tnf Positive_regulation of Prkce 1 0.26 1.43 0.78
68 INT157914 Trpv1 Regulation of Prkca 1 0.07 0.55 0.78
69 INT262582 F2rl1 Regulation of Positive_regulation of Prkca 1 0.03 0.58 0.78
70 INT81711 ITGAL Regulation of Gene_expression of ITGB2 1 0.30 0.17 0.78
71 INT157917 TRPV1 Regulation of Prkca 1 0.04 0.55 0.78
72 INT190867 Binding of Marcks and Prkca 1 0.17 0.8 0.77
73 INT231031 Egf Positive_regulation of Sec22b 1 0.03 0.05 0.76
74 INT185140 Elane Positive_regulation of Prkca 1 0.00 0 0.74
75 INT262573 Par2 Regulation of Positive_regulation of Prkca 1 0.05 0.57 0.72
76 INT220746 EGF Positive_regulation of Gene_expression of GOPC 1 0.13 0 0.72
77 INT262581 Prkca Positive_regulation of Phosphorylation of Trpv1 1 0.13 0.28 0.71
78 INT262574 Gnaq Positive_regulation of Prkca 1 0.00 0.57 0.71
79 INT148454 Gene_expression of Inhbe Positive_regulation of Prkce 1 0.08 0.67 0.69
80 INT220738 EGF Regulation of Gene_expression of EGFR 1 0.09 0.6 0.67
81 INT169213 Binding of EGFR and CARTPT 1 0.00 0.22 0.67
82 INT154766 Nox1 Positive_regulation of Localization of Prkce 1 0.47 0.45 0.66
83 INT261835 Camk2a Positive_regulation of Prkca 1 0.01 0.32 0.66
84 INT112513 Binding of Prkaca and Prkce 1 0.04 0.4 0.64
85 INT112516 Binding of Prkce and Trib3 1 0.01 0.4 0.64
86 INT169287 EGF Positive_regulation of Localization of IL8 1 0.15 0.13 0.61
87 INT169294 EGF Positive_regulation of Localization of IL6 1 0.18 0.13 0.61
88 INT221246 Prkca Negative_regulation of Ptpn2 1 0.04 0.54 0.6
89 INT100225 Binding of Egf and Src 1 0.01 0.67 0.58
90 INT199976 EGF Regulation of ITGB3BP 1 0.02 0.77 0.57
91 INT169286 CNR1 Positive_regulation of Phosphorylation of EGFR 1 0.45 0.18 0.57
92 INT121994 EGF Positive_regulation of Positive_regulation of MAPK1 1 0.25 0 0.55
93 INT121993 Binding of EGF and SGCG 1 0.40 0 0.55
94 INT296483 Prkca Positive_regulation of Localization of GRIP1 1 0.02 0.31 0.55
95 INT296462 Prkca Positive_regulation of Phosphorylation of Gria2 1 0.15 0.3 0.55
96 INT144129 Prkce Positive_regulation of Phosphorylation of Gja1 1 0.42 0.48 0.55
97 INT182553 Ptger2 Regulation of Localization of Prkca 1 0.08 0.69 0.53
98 INT137685 Phosphorylation of Prkca Negative_regulation of Binding of Srpx2 1 0.18 0 0.53
99 INT235876 Hspg2 Positive_regulation of Prkca 1 0.03 0.23 0.53
100 INT144128 Binding of Gja1 and Prkce 1 0.40 0.5 0.52
101 INT140356 Prkca Regulation of Phosphorylation of Prkce 1 0.18 0.44 0.52
102 INT220745 EGF Positive_regulation of Positive_regulation of PCa 1 0.05 0.79 0.52
103 INT151220 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Prkca 1 0.00 0.13 0.51
104 INT151219 Negative_regulation of SIGMAR1 Negative_regulation of Prkca 1 0.00 0.13 0.51
105 INT150833 Esr1 Positive_regulation of Localization of Prkce 1 0.08 0.29 0.51
106 INT98735 Src Negative_regulation of Egf 1 0.26 0.15 0.5
107 INT235885 Prkca Negative_regulation of Slc6a4 1 0.05 0.14 0.49
108 INT220741 Binding of EGFR and SOAT1 1 0.02 0.37 0.49
109 INT98734 Egf Negative_regulation of Tk1 1 0.13 0.15 0.49
110 INT295708 Binding of EGF and CCL2 1 0.01 0.79 0.49
111 INT108329 EGF Positive_regulation of Phosphorylation of EPHB2 4 0.48 3.96 0.48
112 INT71178 Binding of ITGB2 and Icam1 1 0.45 1.2 0.47
113 INT296466 Prkca Regulation of Phosphorylation of Rbm39 1 0.00 0.27 0.47
114 INT147444 PDGFA Positive_regulation of Gene_expression of Ros1 2 0.00 0.95 0.46
115 INT108332 EGF Positive_regulation of Phosphorylation of MAPK1 5 0.48 1.85 0.45
116 INT244050 Binding of Gnb2l1 and Prkca 1 0.01 0 0.45
117 INT262575 Trpv1 Positive_regulation of Prkca 1 0.13 0.17 0.44
118 INT191896 Pbsn Positive_regulation of Prkca 1 0.04 0.85 0.44
119 INT48383 CSF2 Regulation of Gene_expression of ITGB2 1 0.11 0.2 0.44
120 INT48389 CSF3 Regulation of Gene_expression of ITGB2 1 0.25 0.2 0.44
121 INT295406 Egf Regulation of Gene_expression of Oprk1 1 0.01 0.72 0.43
122 INT311590 EGF Regulation of Gene_expression of CXCL10 1 0.23 0.51 0.43
123 INT311589 EGF Regulation of Gene_expression of VEGFA 1 0.18 0.51 0.43
124 INT311591 CXCL10 Regulation of Gene_expression of EGF 1 0.23 0.51 0.43
125 INT196881 Ly6 Positive_regulation of Prkca 2 0.01 0.25 0.42
126 INT13281 Egf Regulation of Ngf 1 0.66 0.12 0.42
127 INT13279 Ngf Regulation of Egf 1 0.49 0.12 0.42
128 INT13283 Egf Regulation of Fgf2 1 0.49 0.11 0.41
129 INT13284 Fgf2 Regulation of Egf 1 0.49 0.11 0.41
130 INT319308 Socs4 Positive_regulation of Prkca 1 0.05 0.67 0.41
131 INT238384 Tlr4 Positive_regulation of Prkca 1 0.06 0.81 0.4
132 INT235860 Prkca Regulation of Akap5 1 0.16 0 0.39
133 INT90807 EGF Positive_regulation of Oprd1 1 0.00 0.39 0.39
134 INT306693 Prkca Regulation of Positive_regulation of Nav1 1 0.10 0.06 0.39
135 INT244046 Binding of Gabrg1 and Prkca 1 0.06 0 0.39
136 INT283840 Binding of Egf and hb 1 0.21 1.34 0.38
137 INT272751 EGFR Regulation of Negative_regulation of Prkca 1 0.01 0 0.38
138 INT272726 Mdk Regulation of Negative_regulation of Prkca 1 0.00 0 0.38
139 INT118285 Binding of EFNA1 and HLA-B 1 0.03 0.29 0.37
140 INT207643 Prkca Positive_regulation of Mapk1 1 0.09 0.17 0.37
141 INT356274 Egf Positive_regulation of Localization of Stat3 1 0.13 0.22 0.36
142 INT295407 Egf Positive_regulation of Localization of Oprk1 1 0.02 0.67 0.36
143 INT211492 Positive_regulation of GRIN1 Positive_regulation of Prkca 1 0.01 0.87 0.36
144 INT94875 Binding of Calca and Egf 1 0.25 0 0.35
145 INT253944 Positive_regulation of Prkca Positive_regulation of Gene_expression of Ins1 1 0.01 1.53 0.35
146 INT235859 Binding of Prkca and Akap5 1 0.13 0 0.35
147 INT188193 Negative_regulation of EGF Positive_regulation of MAPK1 1 0.28 0.54 0.34
148 INT156831 EGF Positive_regulation of MAPK1 2 0.45 0.27 0.33
149 INT324525 PGE Positive_regulation of Positive_regulation of Egfr 1 0.41 1.05 0.33
150 INT324522 PGE Positive_regulation of Phosphorylation of Egfr 1 0.56 1.04 0.33
151 INT324524 PGE Positive_regulation of Egfr 1 0.38 1.05 0.33
152 INT220740 EGF Positive_regulation of Regulation of NAV1 1 0.31 0.61 0.32
153 INT220749 EGF Positive_regulation of Positive_regulation of KRT20 1 0.01 0.61 0.32
154 INT299549 Binding of TGFB1 and Egf 1 0.02 0.32 0.32
155 INT207631 Hspg2 Positive_regulation of Gene_expression of Prkca 1 0.03 0.08 0.31
156 INT196883 Prkca Regulation of P2rx1 1 0.05 0.45 0.31
157 INT75769 Egf Positive_regulation of Cpox 1 0.26 0.76 0.31
158 INT170496 Egf Positive_regulation of Mapk1 3 0.21 0.5 0.3
159 INT356288 Egf Positive_regulation of Trib3 1 0.00 0.17 0.3
160 INT307215 Negative_regulation of Prkca Negative_regulation of Ppara 1 0.09 0.21 0.3
161 INT296473 Prkca Regulation of Serac1 1 0.00 0.14 0.3
162 INT333398 CFD Negative_regulation of Gene_expression of Pdgfa 1 0.02 0.64 0.3
163 INT202313 Gene_expression of PDGFB Positive_regulation of Positive_regulation of Pdgfrb 1 0.14 1 0.29
164 INT185799 Binding of EGFR and SPP1 1 0.19 0.64 0.29
165 INT185144 Prkca Positive_regulation of Snrpd1 1 0.00 0.16 0.29
166 INT137683 Positive_regulation of Binding of Cyp27b1 and Prkca 1 0.03 0 0.29
167 INT137684 Binding of Cyp27b1 and Prkca 1 0.02 0 0.29
168 INT202314 Gene_expression of PDGFB Positive_regulation of Phosphorylation of Pdgfrb 1 0.14 1 0.29
169 INT170128 Binding of ITGAL and ITGB2 2 0.04 1.6 0.28
170 INT166093 Negative_regulation of ROS1 Negative_regulation of Positive_regulation of EGFR 1 0.12 0.33 0.28
171 INT303440 Egf Positive_regulation of Gene_expression of Col7a1 1 0.07 0.92 0.28
172 INT207634 Prkca Negative_regulation of Positive_regulation of Mapk1 1 0.08 0.1 0.28
173 INT166094 Negative_regulation of CSK Negative_regulation of Positive_regulation of EGFR 1 0.02 0.33 0.28
174 INT221236 Ros1 Positive_regulation of Localization of Prkca 1 0.01 0.15 0.27
175 INT193027 EGF Positive_regulation of Positive_regulation of MRGPRX1 1 0.02 0 0.27
176 INT285243 EGF Positive_regulation of Egf 1 0.00 1.55 0.27
177 INT285238 EGF Positive_regulation of VEGFA 1 0.01 1.55 0.27
178 INT144255 EGF Regulation of Positive_regulation of NFKB1 1 0.41 0.66 0.27
179 INT355734 Pdgfb Regulation of Bdnf 1 0.22 1.5 0.27
180 INT224457 TNF Positive_regulation of Pdgfa 1 0.34 1.22 0.27
181 INT338039 F2 Positive_regulation of Positive_regulation of Prkca 1 0.04 0.52 0.27
182 INT195898 Negative_regulation of Egf Negative_regulation of Gene_expression of Cpox 1 0.03 0.3 0.26
183 INT171384 Egf Negative_regulation of Positive_regulation of Mapk1 1 0.16 0.24 0.26
184 INT234980 Positive_regulation of Egfr Positive_regulation of Adam17 1 0.09 1.33 0.26
185 INT196880 Binding of Ly6 and Prkca 1 0.01 0.18 0.25
186 INT191894 Prkca Positive_regulation of Mapk3 1 0.05 0.33 0.25
187 INT332242 Binding of Egf and Pdgfa 1 0.07 0.97 0.25
188 INT258521 EGFR Positive_regulation of MMP2 1 0.39 0.91 0.24
189 INT207641 Positive_regulation of Prkca Positive_regulation of Mapk1 1 0.08 0.09 0.24
190 INT356098 Prkca Regulation of Prkaca 1 0.01 0.11 0.24
191 INT207632 Prkca Positive_regulation of Phosphorylation of Mapk1 1 0.08 0 0.23
192 INT9720 Binding of TGFB1 and Egf 1 0.01 0 0.23
193 INT220750 EGF Positive_regulation of PCa 1 0.05 0.45 0.23
194 INT258565 EGFR Positive_regulation of Meta 1 0.39 0.89 0.23
195 INT173294 LPA Positive_regulation of EGF 1 0.01 0.07 0.23
196 INT272753 Positive_regulation of Prkaca Positive_regulation of EGFR 1 0.01 0 0.23
197 INT173292 F2 Positive_regulation of EGF 1 0.00 0.07 0.23
198 INT9717 Binding of Egf and Fgfr1 1 0.15 0 0.22
199 INT9716 Binding of Egf and Pdgfc 1 0.20 0 0.22
200 INT193033 Binding of CHRM1 and EGF 1 0.01 1.96 0.22

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of peptidyl-tyrosine phosphorylation. They are ordered first by their pain relevance and then by number of times they were reported in regulation of peptidyl-tyrosine phosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91
2 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66
3 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97
4 INT57442 Phosphorylation of Prkca 98 0.70 31.58 41.04
5 INT64164 Regulation of Prkca 34 0.62 10.44 30.99
6 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47
7 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69
8 INT11157 Binding of EGF 88 0.48 53.73 21.25
9 INT117527 Binding of Prkca 25 0.48 6.43 21.05
10 INT10918 Gene_expression of ITGB2 93 0.76 71.8 16.34
11 INT79458 Localization of Prkca 30 0.81 11.13 15.78
12 INT96775 Gene_expression of Pdgfa 42 0.54 29.78 15.46
13 INT27739 Positive_regulation of EGF 49 0.70 28.31 13.68
14 INT76469 Positive_regulation of Gene_expression of Prkca 18 0.46 7.9 13.36
15 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32
16 INT13823 Gene_expression of Egf 97 0.78 39.99 12.99
17 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55
18 INT88650 Negative_regulation of Prkce 13 0.57 11.93 11.16
19 INT91948 Positive_regulation of Prkce 16 0.64 11.36 10.32
20 INT112940 Negative_regulation of Positive_regulation of Prkca 12 0.45 5.85 10
21 INT102865 Positive_regulation of Positive_regulation of Prkca 25 0.69 8.34 9.9
22 INT2036 Localization of EGF 42 0.77 21.5 9.74
23 INT72148 Positive_regulation of Prkce 17 0.68 5.06 9.44
24 INT24328 Gene_expression of Egf 97 0.75 59.65 9.42
25 INT22771 Positive_regulation of Egf 44 0.70 16.45 8.64
26 INT113705 Gene_expression of Egfr 228 0.78 149.05 7.59
27 INT96994 Phosphorylation of EGFR 99 0.82 52.75 7.33
28 INT110104 Localization of Prkce 17 0.79 3.75 6.92
29 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9
30 INT2037 Negative_regulation of EGF 30 0.59 15.05 6.81
31 INT13822 Localization of Egf 30 0.81 13.79 6.4
32 INT11154 Binding of EGFR 149 0.48 96.23 6.29
33 INT123045 Negative_regulation of Phosphorylation of Prkca 9 0.46 5.73 5.77
34 INT112124 Positive_regulation of Egfr 71 0.70 47.82 5.61
35 INT101497 Phosphorylation of Prkce 9 0.81 2.55 5.59
36 INT91946 Regulation of Prkce 6 0.44 4.13 5.46
37 INT10919 Positive_regulation of ITGB2 25 0.67 13.75 5.45
38 INT96778 Positive_regulation of Pdgfa 22 0.46 12.7 5.31
39 INT37227 Regulation of EGF 19 0.45 11.16 5.17
40 INT21901 Negative_regulation of Egf 25 0.58 10.46 4.99
41 INT109838 Phosphorylation of Prkce 6 0.67 5.26 4.95
42 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93
43 INT57441 Positive_regulation of Phosphorylation of Prkca 9 0.40 2.72 4.89
44 INT83205 Negative_regulation of Negative_regulation of Prkca 6 0.43 1.14 4.87
45 INT64160 Negative_regulation of Gene_expression of Prkca 8 0.43 3.01 4.72
46 INT79460 Positive_regulation of Localization of Prkca 11 0.70 2.72 4.71
47 INT60758 Gene_expression of Prkce 8 0.20 4.12 4.59
48 INT103914 Phosphorylation of Egfr 35 0.82 16.98 4.31
49 INT65926 Positive_regulation of Gene_expression of Egf 26 0.70 12.91 4.18
50 INT23653 Binding of Egf 22 0.36 11.34 4.12
51 INT96776 Positive_regulation of Gene_expression of Pdgfa 8 0.40 7.79 3.93
52 INT76466 Regulation of Gene_expression of Prkca 6 0.45 0.94 3.91
53 INT70326 Positive_regulation of Gene_expression of ITGB2 24 0.67 15.42 3.86
54 INT118154 Positive_regulation of Binding of Prkca 2 0.50 0.58 3.81
55 INT120715 Positive_regulation of Egfr 15 0.68 5.53 3.77
56 INT154225 Negative_regulation of Binding of Prkca 2 0.30 0.06 3.71
57 INT119506 Negative_regulation of Egfr 32 0.55 23.75 3.67
58 INT31758 Positive_regulation of Egf 32 0.66 19.42 3.64
59 INT18920 Binding of Egf 24 0.48 9.43 3.57
60 INT96777 Localization of Pdgfa 12 0.79 5.86 3.52
61 INT8096 Positive_regulation of Gene_expression of EGF 21 0.69 13.43 3.47
62 INT83206 Regulation of Regulation of Prkca 3 0.45 1.34 3.46
63 INT163832 Negative_regulation of Gene_expression of EGFR 50 0.59 39.71 3.45
64 INT109840 Localization of Prkce 5 0.74 3.01 3.45
65 INT22375 Localization of PDGFA 21 0.75 15.46 3.25
66 INT118153 Regulation of Positive_regulation of Prkca 5 0.45 3.15 3.23
67 INT53683 Negative_regulation of Gene_expression of ITGB2 10 0.57 9.11 3.2
68 INT70885 Gene_expression of Pdgfb 48 0.67 42.27 3.19
69 INT110100 Negative_regulation of Prkce 5 0.57 0.68 3.16
70 INT124954 Gene_expression of Egfr 26 0.75 15.08 3.12
71 INT120562 Negative_regulation of Egfr 108 0.59 79.38 3.11
72 INT190860 Regulation of Localization of Prkca 4 0.21 1.61 3.11
73 INT117348 Regulation of EGFR 75 0.61 47.73 3.09
74 INT91173 Gene_expression of Pdgfrb 33 0.65 32.55 3.09
75 INT67333 Negative_regulation of ITGB2 10 0.41 6.92 3.06
76 INT31757 Negative_regulation of Egf 18 0.41 9.7 2.94
77 INT117785 Regulation of Gene_expression of EGF 7 0.44 4.22 2.87
78 INT271599 Phosphorylation of Pdgfa 1 0.11 2.55 2.81
79 INT172963 Negative_regulation of Pdgfa 11 0.21 12.94 2.64
80 INT128184 Positive_regulation of Positive_regulation of Prkce 4 0.41 1.3 2.64
81 INT28878 Negative_regulation of Localization of Egf 6 0.49 10.34 2.57
82 INT77636 Phosphorylation of Egf 11 0.61 1.69 2.56
83 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5
84 INT184583 Regulation of Phosphorylation of Prkca 3 0.21 1.76 2.5
85 INT137908 Phosphorylation of Pdgfrb 14 0.81 8.44 2.45
86 INT223080 Binding of Pdgfa 8 0.18 7.21 2.44
87 INT87323 Binding of ITGB2 16 0.47 9.91 2.24
88 INT128185 Gene_expression of Prkce 4 0.69 1.39 2.23
89 INT163545 Gene_expression of PDGFRB 39 0.78 25.5 2.2
90 INT51461 Gene_expression of Itgb2 7 0.75 5.48 2.2
91 INT103917 Positive_regulation of Phosphorylation of Egfr 12 0.68 7.23 2.18
92 INT82226 Negative_regulation of Gene_expression of EGF 11 0.58 6.36 2.13
93 INT108335 Phosphorylation of EGF 17 0.80 7.3 2.09
94 INT136941 Positive_regulation of Localization of Prkce 3 0.43 1.42 2.06
95 INT124052 Binding of Prkce 2 0.06 2.52 2.03
96 INT102866 Regulation of Negative_regulation of Prkca 2 0.43 1.27 1.95
97 INT137906 Positive_regulation of Phosphorylation of Pdgfrb 6 0.50 2.55 1.94
98 INT144020 Positive_regulation of Pdgfrb 30 0.69 24.8 1.92
99 INT52618 Positive_regulation of Pdgfc 3 0.33 0.82 1.9
100 INT65545 Localization of EGFR 35 0.79 20.8 1.88
101 INT170345 Negative_regulation of Localization of Prkca 5 0.23 0.88 1.88
102 INT112131 Positive_regulation of Positive_regulation of Egfr 10 0.49 9.95 1.85
103 INT120563 Positive_regulation of Gene_expression of Egfr 56 0.70 46.19 1.82
104 INT172961 Localization of Egf 26 0.71 16.74 1.81
105 INT73721 Negative_regulation of Gene_expression of Egf 5 0.43 2.28 1.8
106 INT90800 Negative_regulation of Positive_regulation of EGF 5 0.40 2.78 1.77
107 INT124953 Negative_regulation of Gene_expression of Egfr 6 0.42 1.97 1.75
108 INT20992 Regulation of ITGB2 11 0.37 9.04 1.73
109 INT19747 Regulation of Egf 14 0.46 4.67 1.68
110 INT118286 Binding of EFNA1 3 0.21 4.95 1.55
111 INT118292 Negative_regulation of Phosphorylation of EGFR 27 0.59 13.62 1.54
112 INT114525 Negative_regulation of Positive_regulation of Egf 4 0.35 2.93 1.5
113 INT138699 Gene_expression of Pdgfc 5 0.30 3.32 1.46
114 INT111162 Negative_regulation of EFNA1 2 0.03 2.78 1.45
115 INT86382 Negative_regulation of Localization of EGF 5 0.43 1.75 1.44
116 INT96993 Positive_regulation of Phosphorylation of EGFR 15 0.59 5.44 1.37
117 INT44529 Positive_regulation of Pdgfb 11 0.43 7.98 1.36
118 INT56365 Regulation of Gene_expression of ITGB2 5 0.60 3.87 1.36
119 INT127725 Negative_regulation of Positive_regulation of EGFR 6 0.57 2.69 1.3
120 INT91947 Negative_regulation of Negative_regulation of Prkce 1 0.42 0.69 1.3
121 INT95116 Negative_regulation of PDGFA 24 0.57 19.56 1.29
122 INT144019 Negative_regulation of Pdgfrb 21 0.58 14.93 1.26
123 INT110099 Positive_regulation of Localization of Prkce 4 0.68 1.3 1.25
124 INT91949 Regulation of Positive_regulation of Prkce 1 0.44 0.72 1.24
125 INT100909 Negative_regulation of Gene_expression of Itgb2 2 0.41 1.79 1.22
126 INT27108 Positive_regulation of Localization of Egf 5 0.50 2.91 1.21
127 INT61094 Gene_expression of Pdgfc 3 0.09 1.97 1.21
128 INT110106 Regulation of Prkce 4 0.44 0.4 1.2
129 INT70886 Positive_regulation of Gene_expression of Pdgfb 13 0.45 12.57 1.17
130 INT58311 Regulation of Localization of EGF 3 0.54 1.06 1.16
131 INT162124 Positive_regulation of Phosphorylation of Egf 3 0.45 0.77 1.14
132 INT110102 Negative_regulation of Localization of Prkce 3 0.49 0.17 1.13
133 INT210392 Regulation of PDGFA 10 0.36 11.41 1.12
134 INT22770 Regulation of Gene_expression of Egf 5 0.44 2.56 1.12
135 INT131238 Negative_regulation of Positive_regulation of Prkce 1 0.41 0.44 1.12
136 INT118293 Regulation of Phosphorylation of EGFR 2 0.61 1.01 1.1
137 INT37207 Positive_regulation of Positive_regulation of Egf 4 0.50 0.76 1.07
138 INT13817 Protein_catabolism of EGF 3 1.00 1.44 1.06
139 INT70329 Positive_regulation of Positive_regulation of ITGB2 3 0.67 0 1.06
140 INT105860 Positive_regulation of Positive_regulation of EGF 6 0.64 2.37 1.05
141 INT184240 Positive_regulation of Localization of Egf 2 0.27 3.58 0.99
142 INT100911 Positive_regulation of Itgb2 1 0.51 1.62 0.99
143 INT86384 Negative_regulation of Localization of EGFR 4 0.43 2.5 0.97
144 INT11160 Regulation of Gene_expression of EGFR 27 0.62 22.05 0.96
145 INT135111 Regulation of Gene_expression of Prkce 1 0.51 0.15 0.96
146 INT135115 Regulation of Localization of Prkce 1 0.38 0.15 0.96
147 INT96774 Positive_regulation of Localization of Pdgfa 3 0.69 1.21 0.95
148 INT46485 Positive_regulation of Pdgfc 3 0.18 2.74 0.92
149 INT188317 Positive_regulation of Gene_expression of PDGFA 15 0.46 12.7 0.91
150 INT271598 Negative_regulation of Phosphorylation of Pdgfa 1 0.05 0.77 0.88
151 INT178803 Gene_expression of Itgb2 10 0.44 5.13 0.87
152 INT118290 Regulation of Phosphorylation of EGF 1 0.32 0.72 0.87
153 INT271597 Regulation of Gene_expression of Pdgfa 1 0.05 0.81 0.87
154 INT317485 Regulation of Binding of Prkca 1 0.17 0.17 0.87
155 INT144415 Regulation of Positive_regulation of Egfr 2 0.27 0.42 0.86
156 INT136944 Positive_regulation of Positive_regulation of Prkce 2 0.46 0.8 0.85
157 INT171372 Positive_regulation of Gene_expression of Egf 16 0.66 9.82 0.84
158 INT117347 Positive_regulation of Positive_regulation of EGFR 15 0.69 11.17 0.84
159 INT144416 Regulation of Egfr 5 0.57 4.97 0.83
160 INT171361 Regulation of Egfr 16 0.62 8.36 0.81
161 INT144414 Positive_regulation of Positive_regulation of Egfr 1 0.49 0.65 0.8
162 INT171096 Transcription of PDGFA 5 0.47 4.42 0.79
163 INT131286 Binding of Egfr 26 0.44 13.58 0.78
164 INT138955 Transcription of EGFR 18 0.71 11.39 0.78
165 INT31759 Negative_regulation of Gene_expression of Egf 6 0.53 5.33 0.77
166 INT186119 Protein_catabolism of EGFR 6 0.98 3.68 0.76
167 INT95118 Negative_regulation of Gene_expression of PDGFA 4 0.54 5.03 0.76
168 INT164756 Negative_regulation of PDGFRB 32 0.57 21.69 0.72
169 INT100910 Regulation of Positive_regulation of Itgb2 1 0.20 0.53 0.72
170 INT22772 Positive_regulation of Negative_regulation of Egf 1 0.50 1.48 0.71
171 INT109839 Positive_regulation of Phosphorylation of Prkce 1 0.18 1.27 0.71
172 INT114246 Positive_regulation of Negative_regulation of EGFR 13 0.49 8.67 0.7
173 INT70652 Negative_regulation of Binding of EGF 7 0.43 4.23 0.7
174 INT51459 Positive_regulation of Gene_expression of Itgb2 2 0.37 1.92 0.7
175 INT154761 Positive_regulation of Gene_expression of Prkce 1 0.44 0.5 0.7
176 INT154762 Negative_regulation of Phosphorylation of Prkce 1 0.38 0.48 0.69
177 INT171364 Localization of Pdgfrb 6 0.37 4.98 0.68
178 INT111161 Positive_regulation of EFNA1 6 0.40 4.62 0.68
179 INT91172 Positive_regulation of Gene_expression of Pdgfrb 4 0.38 2.83 0.68
180 INT186117 Negative_regulation of Protein_catabolism of EGFR 1 0.42 0.67 0.68
181 INT186118 Positive_regulation of Protein_catabolism of EGFR 1 0.68 0.66 0.68
182 INT110854 Phosphorylation of Egf 8 0.75 5.62 0.67
183 INT94211 Positive_regulation of Negative_regulation of Prkca 1 0.43 0 0.67
184 INT171380 Positive_regulation of Localization of Pdgfrb 1 0.21 0.48 0.66
185 INT228279 Regulation of Gene_expression of Egf 7 0.43 6.64 0.65
186 INT210390 Binding of PDGFA 12 0.36 6.78 0.63
187 INT79459 Protein_catabolism of Prkca 2 1.00 0.09 0.6
188 INT277699 Gene_expression of Pdgfb 5 0.20 4.84 0.59
189 INT320644 Binding of Egfr 7 0.34 5.9 0.56
190 INT260422 Positive_regulation of Localization of EGF 3 0.10 1.58 0.56
191 INT61945 Negative_regulation of Positive_regulation of ITGB2 3 0.41 1.35 0.56
192 INT152068 Regulation of Gene_expression of Prkce 1 0.05 0.74 0.56
193 INT115532 Negative_regulation of Positive_regulation of Egf 3 0.28 1.38 0.52
194 INT144024 Negative_regulation of Phosphorylation of Pdgfrb 6 0.42 3.48 0.51
195 INT198048 Protein_catabolism of PDGFA 2 0.28 2.05 0.5
196 INT224442 Negative_regulation of Gene_expression of Pdgfa 2 0.30 2.48 0.5
197 INT343801 Negative_regulation of Transcription of PDGFA 1 0.29 0.37 0.5
198 INT73200 Positive_regulation of PDGFRB 10 0.67 9.67 0.48
199 INT136942 Negative_regulation of Positive_regulation of Prkce 1 0.39 0.66 0.48
200 INT103916 Negative_regulation of Phosphorylation of Egfr 12 0.59 7.03 0.47
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