GO:0050768

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Name negative regulation of neurogenesis
Categary Process
Go Slim No
Go Link GO:0050768
Unique Molecular Interactions 84
Total Molecular Interactions 134
Total Single Events 638
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of neurogenesis. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of neurogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT200322 Binding of Rest and Sp3 1 0.39 2.93 3.98
2 INT200335 Binding of Oprm1 and Rest 1 0.40 0.07 1.7
3 INT167278 Binding of OPRM1 and REST 1 0.08 0.94 1.24
4 INT200312 Rest Regulation of Oprm1 1 0.23 0.27 1.16
5 INT200307 Rest Negative_regulation of Rorb 1 0.00 0.1 1.03
6 INT165941 Bmp7 Positive_regulation of Penk 1 0.28 0.43 0.95
7 INT165942 Bmp7 Positive_regulation of Transcription of Pomc 1 0.29 0.43 0.95
8 INT165940 Bmp7 Positive_regulation of Pomc 1 0.29 0.43 0.95
9 INT200308 Binding of Rest and Rorb 1 0.00 0 0.87
10 INT200317 Rest Negative_regulation of Transcription of Oprm1 1 0.31 0 0.64
11 INT200321 Binding of Rest and Negative_regulation of Gene_expression of Oprm1 1 0.36 0.05 0.49
12 INT200327 Oprm1 Negative_regulation of Gene_expression of Rest 1 0.31 0 0.41
13 INT324802 Binding of Cd24a and Siglecg 1 0.03 1.34 0.4
14 INT200314 Oprm1 Regulation of Rest 1 0.20 0.1 0.39
15 INT200353 Rest Negative_regulation of Oprm1 1 0.31 0.1 0.39
16 INT200302 Rest Regulation of Rorb 1 0.00 0.07 0.38
17 INT340609 Bdnf Regulation of Gene_expression of Wnt3a 1 0.53 0.31 0.36
18 INT200333 Binding of Rest and Sp1 1 0.24 0.07 0.35
19 INT200316 Sp1 Regulation of Gene_expression of Rest 1 0.31 0 0.35
20 INT200352 Binding of Rest and Rcor2 1 0.16 0.44 0.34
21 INT200351 Sp1 Positive_regulation of Gene_expression of Rest 1 0.34 0.07 0.3
22 INT130108 DLL3 Negative_regulation of Positive_regulation of MAPK1 1 0.13 0 0.28
23 INT118461 Bmp7 Positive_regulation of Th 1 0.31 0.06 0.25
24 INT200309 Positive_regulation of Binding of Rest and Sp3 1 0.41 0.88 0.24
25 INT97691 Binding of REST and HDAC9 1 0.26 0.09 0.23
26 INT97694 Ngf Negative_regulation of Gene_expression of REST 1 0.01 0.09 0.21
27 INT324824 Positive_regulation of Binding of Cd24a and Siglecg 1 0.03 0.68 0.2
28 INT64964 Binding of Alb and Cd24 1 0.02 0.2 0.2
29 INT324822 Binding of Cd24a and Hsp90aa1 1 0.10 0.71 0.19
30 INT324797 Binding of Cd24a and Hmgb1 1 0.19 0.66 0.19
31 INT104797 Smarce1 Positive_regulation of REST 1 0.01 0.24 0.15
32 INT340608 Binding of Creb1 and Wnt3a 1 0.30 0.24 0.14
33 INT213551 Proc Regulation of Bmp7 1 0.00 0.15 0.14
34 INT88410 BMP7 Negative_regulation of CDK2 1 0.35 0 0.14
35 INT200338 Rest Positive_regulation of Gene_expression of Oprm1 1 0.36 0 0.13
36 INT64966 Binding of AGFG1 and Cd24 1 0.00 0.1 0.1
37 INT153637 Gene_expression of REST Positive_regulation of Gene_expression of Oprm1 1 0.03 0.08 0.1
38 INT153636 Binding of REST and Oprm1 1 0.02 0.09 0.09
39 INT129624 Bmp7 Positive_regulation of Gene_expression of Id2 1 0.26 0.31 0.08
40 INT262939 PAX6 Regulation of CDH4 1 0.02 0.97 0.08
41 INT208299 Binding of Hook3 and IGIP 1 0.03 0.37 0.08
42 INT129623 Bmp7 Positive_regulation of Gene_expression of Id3 1 0.37 0.31 0.08
43 INT129625 Id2 Positive_regulation of Gene_expression of Bmp7 1 0.24 0.31 0.08
44 INT129622 Id3 Positive_regulation of Gene_expression of Bmp7 1 0.25 0.31 0.08
45 INT262937 PAX6 Regulation of CDH8 1 0.03 0.98 0.08
46 INT262944 PAX6 Regulation of CDH6 1 0.03 0.97 0.08
47 INT196213 REST Regulation of Gene_expression of CACNA1A 1 0.46 0.08 0.08
48 INT129627 Bmp7 Positive_regulation of Id2 1 0.24 0.25 0.07
49 INT129626 Bmp7 Positive_regulation of Id3 1 0.25 0.25 0.07
50 INT201973 Bmp7 Positive_regulation of ap 1 0.00 0.18 0.06
51 INT118462 BMP7 Regulation of Bmp7 1 0.19 0 0.06
52 INT287234 PDLIM7 Positive_regulation of Gene_expression of BMP7 1 0.14 0.12 0.03
53 INT200311 Htt Positive_regulation of Rest 1 0.05 0.75 0.03
54 INT280849 REST Negative_regulation of Gene_expression of Avp 1 0.09 0.09 0
55 INT354123 MIR124-1 Negative_regulation of Gene_expression of CTDSP1 1 0.01 0.15 0
56 INT343744 mn Negative_regulation of Regulation of Wnt7a 1 0.01 0.1 0
57 INT196208 REST Regulation of CACNA1A 1 0.46 0.06 0
58 INT196216 Binding of CACNA1A and REST 1 0.28 0 0
59 INT262938 Binding of PAX6 and SIX3 1 0.13 0.9 0
60 INT121179 Binding of Htt and Rest 1 0.07 0.45 0
61 INT289301 Binding of CD59 and Cd24a 1 0.02 1.06 0
62 INT251072 Wnt3a Positive_regulation of Axin2 1 0.23 0.29 0
63 INT326893 Binding of Tcf4 and Wnt3a 1 0.13 0 0
64 INT196038 Gene_expression of Bmp7 Positive_regulation of ALPP 1 0.03 0.1 0
65 INT326896 Wnt3a Positive_regulation of Transcription of PLD2 1 0.24 0.06 0
66 INT306339 Binding of CRX and PAX6 1 0.53 0.27 0
67 INT251070 Wnt3a Positive_regulation of Cldn3 1 0.30 0.29 0
68 INT326894 Wnt3a Positive_regulation of Transcription of Pld1 1 0.24 0.06 0
69 INT88409 BMP7 Positive_regulation of Gene_expression of ACTA1 1 0.09 0 0
70 INT280848 Binding of REST and Rest 1 0.02 0.09 0
71 INT196022 Bmp7 Regulation of Bmp4 1 0.06 0.06 0
72 INT262940 Regulation of Binding of PAX6 and SIX3 1 0.16 0.91 0
73 INT196215 Binding of L1RE1 and REST 1 0.33 0.47 0
74 INT262942 Binding of PAX6 and SOX2 1 0.18 0.9 0
75 INT262943 Regulation of Binding of PAX6 and SOX2 1 0.17 0.91 0
76 INT196209 Binding of REST and SNAP25 1 0.25 0 0
77 INT121178 Binding of Bdnf and Rest 1 0.10 0.91 0
78 INT280837 Binding of Rest and Negative_regulation of Gene_expression of Avp 1 0.00 0.09 0
79 INT196214 Binding of FRAXD and REST 1 0.00 0.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of neurogenesis. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of neurogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT340600 Gene_expression of Wnt3a 1 0.68 2.14 9.14
2 INT97693 Gene_expression of REST 29 0.75 5.51 5.26
3 INT340603 Regulation of Gene_expression of Wnt3a 1 0.54 0.49 3.75
4 INT200248 Gene_expression of Rest 1 0.66 1.25 3.7
5 INT141148 Gene_expression of BMP7 24 0.71 14.34 3.44
6 INT111482 Gene_expression of Cd24a 23 0.72 13.74 3.37
7 INT100295 Gene_expression of Bmp7 27 0.78 14.34 3.3
8 INT340595 Positive_regulation of Gene_expression of Wnt3a 1 0.61 0.86 3.11
9 INT199255 Binding of Rest 14 0.41 1.43 2.94
10 INT55090 Positive_regulation of Wnt7a 13 0.37 2.25 2.2
11 INT130112 Gene_expression of DLL3 1 0.25 0 2
12 INT153635 Positive_regulation of Gene_expression of REST 10 0.54 1.38 1.6
13 INT28367 Positive_regulation of REST 10 0.54 2.07 1.52
14 INT340596 Negative_regulation of Gene_expression of Wnt3a 1 0.51 0.38 1.4
15 INT165005 Binding of REST 26 0.43 2.81 1.39
16 INT165538 Binding of Bmp7 5 0.37 1.87 1.39
17 INT287241 Positive_regulation of BMP7 10 0.43 2.68 1.38
18 INT216380 Gene_expression of PAX6 49 0.78 15.63 1.22
19 INT127647 Regulation of Wnt7a 3 0.07 1.28 1.01
20 INT340604 Regulation of Wnt3a 1 0.24 0 0.95
21 INT190591 Positive_regulation of Rest 3 0.37 2.52 0.92
22 INT200255 Localization of Rest 1 0.68 0.14 0.86
23 INT340843 Binding of Cd24a 1 0.02 0.24 0.8
24 INT141150 Localization of BMP7 4 0.56 2.84 0.76
25 INT28958 Negative_regulation of Wnt7a 3 0.45 0.49 0.65
26 INT100294 Positive_regulation of Gene_expression of Bmp7 8 0.46 5.41 0.61
27 INT89126 Regulation of BMP7 7 0.45 2.5 0.58
28 INT127648 Gene_expression of Wnt7a 2 0.13 1.11 0.56
29 INT200273 Negative_regulation of Rest 1 0.43 0.69 0.55
30 INT153634 Regulation of REST 4 0.48 1.42 0.54
31 INT340842 Regulation of Gene_expression of Cd24a 1 0.42 0.08 0.53
32 INT165537 Negative_regulation of Bmp7 2 0.43 0.55 0.52
33 INT159214 Positive_regulation of Gene_expression of BMP7 6 0.46 2.16 0.51
34 INT64961 Binding of Cd24 4 0.15 0.64 0.5
35 INT326696 Regulation of Cd24a 2 0.44 0 0.48
36 INT129620 Regulation of Gene_expression of Bmp7 3 0.42 3.2 0.47
37 INT340598 Binding of Wnt3a 1 0.33 0.15 0.46
38 INT118460 Binding of Bmp7 3 0.46 1.3 0.4
39 INT165006 Positive_regulation of Binding of REST 1 0.23 0.94 0.4
40 INT340606 Positive_regulation of Wnt3a 1 0.61 0.49 0.4
41 INT130109 Negative_regulation of Gene_expression of DLL3 1 0.14 0 0.38
42 INT200269 Negative_regulation of Transcription of Rest 1 0.31 0.08 0.35
43 INT200245 Transcription of Rest 1 0.51 0.08 0.35
44 INT130110 Regulation of Gene_expression of DLL3 1 0.20 0 0.33
45 INT200270 Regulation of Rest 1 0.20 0.07 0.32
46 INT200256 Negative_regulation of Regulation of Rest 1 0.32 0.07 0.32
47 INT196032 Positive_regulation of Gene_expression of Bmp7 10 0.17 1.31 0.31
48 INT196024 Gene_expression of Bmp7 20 0.26 1.88 0.3
49 INT51514 Positive_regulation of Wnt3a 3 0.04 3.32 0.28
50 INT130115 Positive_regulation of DLL3 1 0.07 0 0.25
51 INT104789 Negative_regulation of REST 3 0.33 0.44 0.23
52 INT339267 Negative_regulation of BMP7 1 0.43 0.55 0.17
53 INT200275 Positive_regulation of Gene_expression of Rest 1 0.59 0.92 0.17
54 INT55089 Positive_regulation of Positive_regulation of Wnt7a 2 0.27 0.06 0.16
55 INT118459 Regulation of Bmp7 3 0.43 0.25 0.15
56 INT201968 Positive_regulation of Bmp7 2 0.43 1.11 0.14
57 INT51512 Negative_regulation of Positive_regulation of Wnt3a 1 0.04 1.3 0.13
58 INT51513 Positive_regulation of Positive_regulation of Wnt3a 1 0.04 1.31 0.13
59 INT200281 Negative_regulation of Negative_regulation of Rest 1 0.31 0.44 0.11
60 INT254742 Gene_expression of Cd24 1 0.11 0.46 0.09
61 INT254732 Localization of Cd24 1 0.12 0.46 0.09
62 INT355318 Positive_regulation of Gene_expression of Cd24a 1 0.47 1.17 0.09
63 INT214463 Binding of Wnt3a 2 0.26 0.23 0.08
64 INT235781 Positive_regulation of PAX6 2 0.50 0.36 0.08
65 INT196248 Localization of REST 1 0.66 0.15 0.08
66 INT208271 Binding of Hook3 1 0.03 0.36 0.08
67 INT355332 Localization of Bmp7 1 0.09 1.92 0.08
68 INT316570 Binding of BMP7 3 0.37 0.95 0.07
69 INT287244 Transcription of BMP7 1 0.66 0.15 0.07
70 INT254740 Negative_regulation of Cd24 1 0.07 0.08 0.07
71 INT287242 Positive_regulation of Transcription of BMP7 1 0.64 0.15 0.07
72 INT262953 Binding of PAX6 13 0.48 5.28 0.06
73 INT262951 Transcription of PAX6 6 0.72 3.33 0.06
74 INT262955 Regulation of PAX6 2 0.27 0.87 0.06
75 INT153022 Negative_regulation of Bmp7 1 0.01 0.27 0.06
76 INT159426 Positive_regulation of Gene_expression of Wnt7a 1 0.10 0.51 0.05
77 INT262963 Negative_regulation of PAX6 4 0.59 4.92 0.04
78 INT235783 Positive_regulation of Gene_expression of PAX6 7 0.50 1.59 0.03
79 INT201965 Transcription of Bmp7 2 0.49 0.93 0.03
80 INT262954 Regulation of Transcription of PAX6 1 0.62 2.33 0.03
81 INT326709 Negative_regulation of Gene_expression of Cd24a 3 0.40 0.86 0
82 INT200854 Transcription of Cd24a 2 0.66 0.4 0
83 INT214465 Localization of Wnt3a 2 0.52 0.29 0
84 INT251053 Gene_expression of Wnt3a 2 0.47 0.5 0
85 INT151839 Positive_regulation of Bmp7 2 0.27 0.24 0
86 INT262959 Localization of PAX6 2 0.75 1.65 0
87 INT262964 Negative_regulation of Binding of PAX6 1 0.43 0.44 0
88 INT326853 Positive_regulation of Gene_expression of Wnt3a 1 0.36 0.2 0
89 INT260766 Negative_regulation of Gene_expression of Bmp7 1 0.35 0 0
90 INT266460 Positive_regulation of Binding of Wnt7a 1 0.04 0.06 0
91 INT354177 Negative_regulation of Gene_expression of CTDSP1 1 0.15 0.18 0
92 INT346707 Negative_regulation of Gene_expression of PAX6 1 0.37 0.5 0
93 INT355323 Negative_regulation of Cd24a 1 0.40 0.08 0
94 INT251054 Regulation of Localization of Wnt3a 1 0.27 0.07 0
95 INT201963 Positive_regulation of Binding of Bmp7 1 0.05 0 0
96 INT266459 Binding of Wnt7a 1 0.03 0.06 0
97 INT314125 Regulation of Transcription of Bmp7 1 0.25 0.88 0
98 INT354163 Regulation of CTDSP1 1 0.16 0.17 0
99 INT354180 Binding of CTDSP1 1 0.13 0.15 0
100 INT354145 Regulation of Gene_expression of CTDSP1 1 0.16 0.18 0
101 INT235782 Negative_regulation of Positive_regulation of PAX6 1 0.24 0 0
102 INT354173 Gene_expression of CTDSP1 1 0.27 0.32 0
103 INT251066 Regulation of Gene_expression of Wnt3a 1 0.31 0.07 0
104 INT314127 Regulation of Bmp7 1 0.25 0.88 0
105 INT196244 Negative_regulation of Gene_expression of REST 1 0.38 0.09 0
106 INT343743 Negative_regulation of Regulation of Wnt7a 1 0.04 0.1 0
107 INT262956 Protein_catabolism of PAX6 1 0.66 0.14 0
108 INT326843 Negative_regulation of Gene_expression of Wnt3a 1 0.22 0.29 0
109 INT196028 Transcription of Bmp7 1 0.18 0 0
110 INT262952 Regulation of Binding of PAX6 1 0.27 0.06 0
111 INT196029 Localization of Bmp7 1 0.27 0.09 0
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