GO:0050785

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Name advanced glycation end-product receptor activity
Categary Function
Go Slim No
Go Link GO:0050785
Unique Molecular Interactions 34
Total Molecular Interactions 67
Total Single Events 390
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for advanced glycation end-product receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for advanced glycation end-product receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT184262 Binding of AGER and HMGB1 1 0.34 4.49 2.17
2 INT266391 Binding of Ager and S100a1 1 0.01 5.63 1.69
3 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57
4 INT266408 Binding of HMGB1 and Ager 1 0.01 2.57 0.76
5 INT266381 Positive_regulation of Ager Positive_regulation of Nfkb1 1 0.00 0.77 0.55
6 INT266376 Binding of Ager and Itgam 1 0.00 2.31 0.54
7 INT184291 Binding of AGER and Crp 1 0.01 1.23 0.46
8 INT184292 Binding of AGER and chromosomal protein 1 1 0.01 0.87 0.41
9 INT266393 Binding of Ager and Fn1 1 0.00 0.82 0.39
10 INT266397 Binding of Ager and Col4a1 1 0.00 0.81 0.38
11 INT266419 HMGB1 Positive_regulation of Ager 1 0.01 1.37 0.37
12 INT266402 Binding of S100P and Ager 1 0.00 2.25 0.35
13 INT266383 Binding of Ager and S100b 1 0.01 3.48 0.33
14 INT266375 S100b Positive_regulation of Ager 1 0.02 1.8 0.31
15 INT238802 Binding of Ager and Renbp 6 0.02 6.46 0.22
16 INT344833 Binding of Ager and Hmgb1 1 0.08 0.72 0.22
17 INT266422 HMGB1 Positive_regulation of Binding of Ager 1 0.01 0.92 0.16
18 INT266412 Binding of S100A12 and Ager 1 0.01 1.03 0.15
19 INT266403 Negative_regulation of Binding of S100P and Ager 1 0.00 0.74 0.13
20 INT308659 Binding of Ager and ecs 1 0.01 1.14 0.12
21 INT308647 Ager Positive_regulation of Gene_expression of Bace1 1 0.09 1.01 0.12
22 INT308660 Binding of Ager and App 1 0.08 1.22 0.12
23 INT266384 Binding of Ager and S100a6 1 0.01 1.32 0.11
24 INT266385 S100a6 Positive_regulation of Ager 1 0.01 0.84 0.1
25 INT266373 Itgam Positive_regulation of Ager 1 0.01 0.84 0.1
26 INT266396 Binding of Ager and S100a4 1 0.01 0.59 0.1
27 INT238803 Ager Positive_regulation of Cbl 1 0.01 1.57 0.04
28 INT266379 S100a8 Positive_regulation of Ager 1 0.01 0.3 0.04
29 INT266392 S100a9 Positive_regulation of Ager 1 0.01 0.3 0.04
30 INT236078 Binding of AGER and HLA-DMA 1 0.08 0.81 0
31 INT262617 Ager Positive_regulation of Rpe 1 0.00 0.81 0
32 INT266407 Binding of ALB and Ager 1 0.00 1.42 0
33 INT266395 Renbp Positive_regulation of Ager 1 0.00 0.31 0
34 INT236079 Binding of AGER and HLA-DQB1 1 0.25 1.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for advanced glycation end-product receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in advanced glycation end-product receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT139830 Gene_expression of AGER 47 0.75 41.71 16.53
2 INT224366 Gene_expression of Ager 111 0.77 125.37 8.49
3 INT184281 Binding of AGER 25 0.37 23.06 7.32
4 INT224369 Binding of Ager 43 0.42 40.57 3.86
5 INT73602 Positive_regulation of Ager 35 0.69 30.66 3.74
6 INT184270 Negative_regulation of AGER 8 0.32 10.48 3.45
7 INT184286 Regulation of AGER 1 0.46 6.7 3
8 INT184280 Positive_regulation of AGER 8 0.52 9.05 2.43
9 INT184284 Regulation of Gene_expression of AGER 1 0.34 4.95 2.11
10 INT184273 Localization of AGER 1 0.60 3.59 1.67
11 INT139829 Negative_regulation of Gene_expression of AGER 2 0.57 3.76 1.3
12 INT184276 Positive_regulation of Negative_regulation of AGER 1 0.35 2.87 1.2
13 INT224368 Negative_regulation of Gene_expression of Ager 8 0.39 13.94 1.03
14 INT184279 Regulation of Regulation of AGER 1 0.20 1.99 0.9
15 INT224365 Positive_regulation of Gene_expression of Ager 13 0.69 11.6 0.88
16 INT224367 Negative_regulation of Ager 15 0.46 25.57 0.78
17 INT139828 Positive_regulation of Gene_expression of AGER 2 0.67 3 0.75
18 INT184290 Regulation of Localization of AGER 1 0.34 1.17 0.59
19 INT184274 Negative_regulation of Binding of AGER 1 0.37 2.02 0.55
20 INT184285 Positive_regulation of Binding of AGER 1 0.38 1.04 0.49
21 INT224372 Regulation of Gene_expression of Ager 6 0.39 4.98 0.43
22 INT266343 Positive_regulation of Positive_regulation of Ager 1 0.02 0.7 0.33
23 INT224370 Localization of Ager 7 0.65 11.64 0.3
24 INT266318 Negative_regulation of Negative_regulation of Ager 1 0.02 0.66 0.29
25 INT224363 Regulation of Ager 3 0.36 4.62 0.26
26 INT184278 Regulation of Binding of AGER 1 0.34 0.52 0.2
27 INT266337 Protein_catabolism of Ager 1 0.02 0.26 0.1
28 INT270684 Positive_regulation of Positive_regulation of AGER 1 0.05 0.87 0.08
29 INT266338 Negative_regulation of Binding of Ager 1 0.02 1.37 0.05
30 INT238794 Positive_regulation of Localization of Ager 1 0.40 1.2 0.03
31 INT224371 Phosphorylation of Ager 1 0.70 0 0
32 INT238789 Regulation of Regulation of Ager 1 0.36 1.1 0
33 INT224364 Negative_regulation of Phosphorylation of Ager 1 0.37 0 0
34 INT238786 Positive_regulation of Binding of Ager 1 0.40 6.84 0
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